LOCUS       DBERAE010000001       172154 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.01, whole genome shotgun sequence.
ACCESSION   DBERAE010000001 DBERAE010000000
VERSION     DBERAE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 172154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 172154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..172154
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.01"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL70N_000001"
     CDS             371..598
                     /locus_tag="ACL70N_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588905.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL70N_000002"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL70N_000002"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGS0588906.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWIKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="ACL70N_000003"
                     /pseudo
     CDS             4798..5250
                     /locus_tag="ACL70N_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            5269..6606
                     /locus_tag="ACL70N_000004"
     CDS             5269..6606
                     /locus_tag="ACL70N_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0588907.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="ACL70N_000005"
     CDS             6685..7569
                     /locus_tag="ACL70N_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0588908.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="ACL70N_000006"
     CDS             7569..8402
                     /locus_tag="ACL70N_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0588909.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLITIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8421..10514
                     /gene="nanB"
                     /locus_tag="ACL70N_000007"
     CDS             8421..10514
                     /gene="nanB"
                     /locus_tag="ACL70N_000007"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGS0588910.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10527..11630
                     /locus_tag="ACL70N_000008"
     CDS             10527..11630
                     /locus_tag="ACL70N_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0588911.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11804..12502
                     /locus_tag="ACL70N_000009"
     CDS             11804..12502
                     /locus_tag="ACL70N_000009"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS0588912.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12521..14038
                     /locus_tag="ACL70N_000010"
     CDS             12521..14038
                     /locus_tag="ACL70N_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS0588913.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14163..15491
                     /locus_tag="ACL70N_000011"
     CDS             14163..15491
                     /locus_tag="ACL70N_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0588914.1"
                     /translation="MKFRKLACTVLAGAVVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15743..16609
                     /locus_tag="ACL70N_000012"
     CDS             15743..16609
                     /locus_tag="ACL70N_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0588915.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16625..17464
                     /locus_tag="ACL70N_000013"
     CDS             16625..17464
                     /locus_tag="ACL70N_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0588916.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17737..18189
                     /locus_tag="ACL70N_000014"
     CDS             17737..18189
                     /locus_tag="ACL70N_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0588917.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18286..18630
                     /locus_tag="ACL70N_000015"
     CDS             18286..18630
                     /locus_tag="ACL70N_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588918.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGAY
                     AAKYGISMARSILSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFAYNIAAAWDA
                     HDKIPNNGRINF"
     gene            18640..18831
                     /locus_tag="ACL70N_000016"
     CDS             18640..18831
                     /locus_tag="ACL70N_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588919.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKK"
     gene            18914..19558
                     /locus_tag="ACL70N_000017"
     CDS             18914..19558
                     /locus_tag="ACL70N_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS0588920.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19727..20644
                     /locus_tag="ACL70N_000018"
     CDS             19727..20644
                     /locus_tag="ACL70N_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGS0588921.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20662..21546
                     /locus_tag="ACL70N_000019"
     CDS             20662..21546
                     /locus_tag="ACL70N_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0588922.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGLVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21562..22413)
                     /locus_tag="ACL70N_000020"
     CDS             complement(21562..22413)
                     /locus_tag="ACL70N_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS0588923.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22613..24670
                     /gene="pbp2b"
                     /locus_tag="ACL70N_000021"
     CDS             22613..24670
                     /gene="pbp2b"
                     /locus_tag="ACL70N_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGS0588924.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24681..25277
                     /gene="recR"
                     /locus_tag="ACL70N_000022"
     CDS             24681..25277
                     /gene="recR"
                     /locus_tag="ACL70N_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGS0588925.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25453..26496
                     /locus_tag="ACL70N_000023"
     CDS             25453..26496
                     /locus_tag="ACL70N_000023"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGS0588926.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26580..27953
                     /gene="murF"
                     /locus_tag="ACL70N_000024"
     CDS             26580..27953
                     /gene="murF"
                     /locus_tag="ACL70N_000024"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGS0588927.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            27940..28551
                     /locus_tag="ACL70N_000025"
     CDS             27940..28551
                     /locus_tag="ACL70N_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGS0588928.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGQREQYLD"
     gene            28642..29346
                     /locus_tag="ACL70N_000026"
     CDS             28642..29346
                     /locus_tag="ACL70N_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGS0588929.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29565..30938
                     /gene="ftsA"
                     /locus_tag="ACL70N_000027"
     CDS             29565..30938
                     /gene="ftsA"
                     /locus_tag="ACL70N_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGS0588930.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30955..32214
                     /gene="ftsZ"
                     /locus_tag="ACL70N_000028"
     CDS             30955..32214
                     /gene="ftsZ"
                     /locus_tag="ACL70N_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGS0588931.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32219..32890
                     /locus_tag="ACL70N_000029"
     CDS             32219..32890
                     /locus_tag="ACL70N_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGS0588932.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32900..33439
                     /locus_tag="ACL70N_000030"
     CDS             32900..33439
                     /locus_tag="ACL70N_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGS0588933.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33439..33702
                     /locus_tag="ACL70N_000031"
     CDS             33439..33702
                     /locus_tag="ACL70N_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGS0588934.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33759..34484
                     /locus_tag="ACL70N_000032"
     CDS             33759..34484
                     /locus_tag="ACL70N_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGS0588935.1"
                     /translation="MEWIKKVEDSYAPFLTPFINPHQEKLLKILAKTYGLACSSSGEF
                     VSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHLTHAKILGTVINQLGIERKLF
                     GDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEERPFTEKIDKLEQYRELDLSV
                     SSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDKSDYTVQVGDLISVRKFGRLR
                     LLQDKGQTKKEKKKITVQLLLSK"
     gene            34493..35281
                     /gene="divIVA"
                     /locus_tag="ACL70N_000033"
     CDS             34493..35281
                     /gene="divIVA"
                     /locus_tag="ACL70N_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGS0588936.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35629..38421
                     /gene="ileS"
                     /locus_tag="ACL70N_000034"
     CDS             35629..38421
                     /gene="ileS"
                     /locus_tag="ACL70N_000034"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGS0588937.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKIIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            38978..39340
                     /locus_tag="ACL70N_000035"
                     /pseudo
     CDS             38978..39340
                     /locus_tag="ACL70N_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            39875..40567
                     /locus_tag="ACL70N_000036"
     CDS             39875..40567
                     /locus_tag="ACL70N_000036"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGS0588938.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            40620..43031
                     /locus_tag="ACL70N_000037"
     CDS             40620..43031
                     /locus_tag="ACL70N_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS0588939.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            43281..43982
                     /locus_tag="ACL70N_000038"
     CDS             43281..43982
                     /locus_tag="ACL70N_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0588940.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            43984..46692
                     /locus_tag="ACL70N_000039"
     CDS             43984..46692
                     /locus_tag="ACL70N_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS0588941.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGCFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NVFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46788..47279)
                     /gene="tpx"
                     /locus_tag="ACL70N_000040"
     CDS             complement(46788..47279)
                     /gene="tpx"
                     /locus_tag="ACL70N_000040"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGS0588942.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(47402..48331)
                     /gene="psaA"
                     /locus_tag="ACL70N_000041"
     CDS             complement(47402..48331)
                     /gene="psaA"
                     /locus_tag="ACL70N_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGS0588943.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKATTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(48363..49211)
                     /locus_tag="ACL70N_000042"
     CDS             complement(48363..49211)
                     /locus_tag="ACL70N_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGS0588944.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(49208..49930)
                     /locus_tag="ACL70N_000043"
     CDS             complement(49208..49930)
                     /locus_tag="ACL70N_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0588945.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            50221..52113
                     /gene="pepO"
                     /locus_tag="ACL70N_000044"
     CDS             50221..52113
                     /gene="pepO"
                     /locus_tag="ACL70N_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGS0588946.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(52236..52865)
                     /locus_tag="ACL70N_000045"
     CDS             complement(52236..52865)
                     /locus_tag="ACL70N_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS0588947.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            53861..56083
                     /locus_tag="ACL70N_000046"
     CDS             53861..56083
                     /locus_tag="ACL70N_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015968 - stringent response [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HGS0588948.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            56113..56556
                     /gene="dtd"
                     /locus_tag="ACL70N_000047"
     CDS             56113..56556
                     /gene="dtd"
                     /locus_tag="ACL70N_000047"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGS0588949.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGANMQVELVNNGPVTIILDTKKR"
     gene            complement(56595..57010)
                     /locus_tag="ACL70N_000048"
                     /pseudo
     CDS             complement(56595..57010)
                     /locus_tag="ACL70N_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            57348..57731
                     /locus_tag="ACL70N_000049"
     CDS             57348..57731
                     /locus_tag="ACL70N_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588950.1"
                     /translation="MQKENVRMRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVR
                     EYVPKKERIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQ
                     AKRIHRAFCVRLCLKAQFLLSNNDS"
     gene            57912..58211
                     /locus_tag="ACL70N_000050"
     CDS             57912..58211
                     /locus_tag="ACL70N_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588951.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(58306..58743)
                     /locus_tag="ACL70N_000051"
     CDS             complement(58306..58743)
                     /locus_tag="ACL70N_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588952.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(58845..59510)
                     /locus_tag="ACL70N_000052"
     CDS             complement(58845..59510)
                     /locus_tag="ACL70N_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HGS0588953.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(59698..60348)
                     /locus_tag="ACL70N_000053"
     CDS             complement(59698..60348)
                     /locus_tag="ACL70N_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGS0588954.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            60460..61302
                     /locus_tag="ACL70N_000054"
     CDS             60460..61302
                     /locus_tag="ACL70N_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0588955.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQENFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            61378..61815
                     /locus_tag="ACL70N_000055"
     CDS             61378..61815
                     /locus_tag="ACL70N_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGS0588956.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            61884..62186
                     /locus_tag="ACL70N_000056"
     CDS             61884..62186
                     /locus_tag="ACL70N_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588957.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(62277..63350)
                     /locus_tag="ACL70N_000057"
     CDS             complement(62277..63350)
                     /locus_tag="ACL70N_000057"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGS0588958.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            63506..64183
                     /locus_tag="ACL70N_000058"
     CDS             63506..64183
                     /locus_tag="ACL70N_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0588959.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            64176..65150
                     /locus_tag="ACL70N_000059"
     CDS             64176..65150
                     /locus_tag="ACL70N_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGS0588960.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLFLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(65199..67142)
                     /gene="thrS"
                     /locus_tag="ACL70N_000060"
     CDS             complement(65199..67142)
                     /gene="thrS"
                     /locus_tag="ACL70N_000060"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGS0588961.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNIAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVNYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(67200..67523)
                     /locus_tag="ACL70N_000061"
     CDS             complement(67200..67523)
                     /locus_tag="ACL70N_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS0588962.1"
                     /translation="MELQELVEHSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(67780..68147)
                     /locus_tag="ACL70N_000062"
                     /pseudo
     CDS             complement(67780..68147)
                     /locus_tag="ACL70N_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            68388..69018
                     /locus_tag="ACL70N_000063"
                     /pseudo
     CDS             68388..69018
                     /locus_tag="ACL70N_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            69159..69428
                     /gene="rpsO"
                     /locus_tag="ACL70N_000064"
     CDS             69159..69428
                     /gene="rpsO"
                     /locus_tag="ACL70N_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGS0588963.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            70244..70858
                     /locus_tag="ACL70N_000065"
     CDS             70244..70858
                     /locus_tag="ACL70N_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGS0588964.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(71151..71900)
                     /locus_tag="ACL70N_000066"
     CDS             complement(71151..71900)
                     /locus_tag="ACL70N_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGS0588965.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMILKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            72033..74369
                     /locus_tag="ACL70N_000067"
     CDS             72033..74369
                     /locus_tag="ACL70N_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS0588966.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            74470..75147
                     /locus_tag="ACL70N_000068"
     CDS             74470..75147
                     /locus_tag="ACL70N_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGS0588967.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            75134..75931
                     /locus_tag="ACL70N_000069"
     CDS             75134..75931
                     /locus_tag="ACL70N_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGS0588968.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            75948..77051
                     /locus_tag="ACL70N_000070"
     CDS             75948..77051
                     /locus_tag="ACL70N_000070"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0588969.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWLSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLSILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            77058..77249
                     /locus_tag="ACL70N_000071"
     CDS             77058..77249
                     /locus_tag="ACL70N_000071"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0588970.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            77352..78371
                     /gene="galE"
                     /locus_tag="ACL70N_000072"
     CDS             77352..78371
                     /gene="galE"
                     /locus_tag="ACL70N_000072"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0588971.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            78373..79338
                     /locus_tag="ACL70N_000073"
     CDS             78373..79338
                     /locus_tag="ACL70N_000073"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0588972.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(79389..79595)
                     /locus_tag="ACL70N_000074"
     CDS             complement(79389..79595)
                     /locus_tag="ACL70N_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGS0588973.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            79647..80123
                     /locus_tag="ACL70N_000075"
     CDS             79647..80123
                     /locus_tag="ACL70N_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGS0588974.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            80132..80803
                     /gene="cmk"
                     /locus_tag="ACL70N_000076"
     CDS             80132..80803
                     /gene="cmk"
                     /locus_tag="ACL70N_000076"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGS0588975.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            80933..81271
                     /locus_tag="ACL70N_000077"
     CDS             80933..81271
                     /locus_tag="ACL70N_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGS0588976.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIHIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            81274..81903
                     /locus_tag="ACL70N_000078"
     CDS             81274..81903
                     /locus_tag="ACL70N_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGS0588977.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            82143..83294
                     /locus_tag="ACL70N_000079"
     CDS             82143..83294
                     /locus_tag="ACL70N_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0588978.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGARLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            83612..84361
                     /gene="truA"
                     /locus_tag="ACL70N_000080"
     CDS             83612..84361
                     /gene="truA"
                     /locus_tag="ACL70N_000080"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGS0588979.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRYYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            84351..85124
                     /locus_tag="ACL70N_000081"
     CDS             84351..85124
                     /locus_tag="ACL70N_000081"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS0588980.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            85102..85563
                     /locus_tag="ACL70N_000082"
     CDS             85102..85563
                     /locus_tag="ACL70N_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0588981.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(85822..86070)
                     /locus_tag="ACL70N_000083"
     CDS             complement(85822..86070)
                     /locus_tag="ACL70N_000083"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0588982.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(86018..87100)
                     /locus_tag="ACL70N_000084"
     CDS             complement(86018..87100)
                     /locus_tag="ACL70N_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS0588983.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(87226..88008)
                     /gene="gatD"
                     /locus_tag="ACL70N_000085"
     CDS             complement(87226..88008)
                     /gene="gatD"
                     /locus_tag="ACL70N_000085"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGS0588984.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(88008..89351)
                     /gene="murT"
                     /locus_tag="ACL70N_000086"
     CDS             complement(88008..89351)
                     /gene="murT"
                     /locus_tag="ACL70N_000086"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGS0588985.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDVQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(89450..90766)
                     /locus_tag="ACL70N_000087"
     CDS             complement(89450..90766)
                     /locus_tag="ACL70N_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGS0588986.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDINGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            90959..92185
                     /locus_tag="ACL70N_000088"
     CDS             90959..92185
                     /locus_tag="ACL70N_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGS0588987.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            92384..93958
                     /locus_tag="ACL70N_000089"
     CDS             92384..93958
                     /locus_tag="ACL70N_000089"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0588988.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            94222..95010
                     /gene="codY"
                     /locus_tag="ACL70N_000090"
     CDS             94222..95010
                     /gene="codY"
                     /locus_tag="ACL70N_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGS0588989.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            95010..95585
                     /locus_tag="ACL70N_000091"
     CDS             95010..95585
                     /locus_tag="ACL70N_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS0588990.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            95667..95752
                     /locus_tag="ACL70N_000092"
     tRNA            95667..95752
                     /locus_tag="ACL70N_000092"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:95701..95703,aa:Leu,seq:aag)
     gene            96035..97165
                     /locus_tag="ACL70N_000093"
     CDS             96035..97165
                     /locus_tag="ACL70N_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0588991.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            97664..98422
                     /locus_tag="ACL70N_000094"
     CDS             97664..98422
                     /locus_tag="ACL70N_000094"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0588992.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            98510..99022
                     /locus_tag="ACL70N_000095"
     CDS             98510..99022
                     /locus_tag="ACL70N_000095"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGS0588993.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            99204..100148
                     /gene="metA"
                     /locus_tag="ACL70N_000096"
     CDS             99204..100148
                     /gene="metA"
                     /locus_tag="ACL70N_000096"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGS0588994.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            100157..100834
                     /locus_tag="ACL70N_000097"
     CDS             100157..100834
                     /locus_tag="ACL70N_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS0588995.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            100932..101690
                     /gene="tpiA"
                     /locus_tag="ACL70N_000098"
     CDS             100932..101690
                     /gene="tpiA"
                     /locus_tag="ACL70N_000098"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGS0588996.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            101728..103233
                     /gene="lytC"
                     /locus_tag="ACL70N_000099"
     CDS             101728..103233
                     /gene="lytC"
                     /locus_tag="ACL70N_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGS0588997.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRNGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            103729..104247
                     /locus_tag="ACL70N_000100"
     CDS             103729..104247
                     /locus_tag="ACL70N_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGS0588998.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            104377..104883
                     /locus_tag="ACL70N_000101"
     CDS             104377..104883
                     /locus_tag="ACL70N_000101"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGS0588999.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            104883..105053
                     /locus_tag="ACL70N_000102"
     CDS             104883..105053
                     /locus_tag="ACL70N_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589000.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            105085..106317
                     /gene="clpX"
                     /locus_tag="ACL70N_000103"
     CDS             105085..106317
                     /gene="clpX"
                     /locus_tag="ACL70N_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGS0589001.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            106326..106913
                     /gene="yihA"
                     /locus_tag="ACL70N_000104"
     CDS             106326..106913
                     /gene="yihA"
                     /locus_tag="ACL70N_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGS0589002.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            106924..107304
                     /locus_tag="ACL70N_000105"
     CDS             106924..107304
                     /locus_tag="ACL70N_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGS0589003.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            107356..108246
                     /gene="rapZ"
                     /locus_tag="ACL70N_000106"
     CDS             107356..108246
                     /gene="rapZ"
                     /locus_tag="ACL70N_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGS0589004.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            108243..109220
                     /locus_tag="ACL70N_000107"
     CDS             108243..109220
                     /locus_tag="ACL70N_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGS0589005.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            109217..110128
                     /gene="whiA"
                     /locus_tag="ACL70N_000108"
     CDS             109217..110128
                     /gene="whiA"
                     /locus_tag="ACL70N_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGS0589006.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(110162..111130)
                     /locus_tag="ACL70N_000109"
     CDS             complement(110162..111130)
                     /locus_tag="ACL70N_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0589007.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            111266..112123
                     /gene="cdaA"
                     /locus_tag="ACL70N_000110"
     CDS             111266..112123
                     /gene="cdaA"
                     /locus_tag="ACL70N_000110"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGS0589008.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            112110..112889
                     /locus_tag="ACL70N_000111"
     CDS             112110..112889
                     /locus_tag="ACL70N_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGS0589009.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            112913..114265
                     /gene="glmM"
                     /locus_tag="ACL70N_000112"
     CDS             112913..114265
                     /gene="glmM"
                     /locus_tag="ACL70N_000112"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGS0589010.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGNIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            114339..114713
                     /locus_tag="ACL70N_000113"
     CDS             114339..114713
                     /locus_tag="ACL70N_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGS0589011.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            114715..115563
                     /locus_tag="ACL70N_000114"
     CDS             114715..115563
                     /locus_tag="ACL70N_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0589012.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            115840..116607
                     /gene="dapB"
                     /locus_tag="ACL70N_000115"
     CDS             115840..116607
                     /gene="dapB"
                     /locus_tag="ACL70N_000115"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGS0589013.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMHIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            116604..117803
                     /locus_tag="ACL70N_000116"
     CDS             116604..117803
                     /locus_tag="ACL70N_000116"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGS0589014.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            117800..119671
                     /locus_tag="ACL70N_000117"
     CDS             117800..119671
                     /locus_tag="ACL70N_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0589015.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(119814..120998)
                     /gene="mntE"
                     /locus_tag="ACL70N_000118"
     CDS             complement(119814..120998)
                     /gene="mntE"
                     /locus_tag="ACL70N_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGS0589016.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            121302..123998
                     /locus_tag="ACL70N_000119"
     CDS             121302..123998
                     /locus_tag="ACL70N_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS0589017.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVDLATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            124011..124802
                     /gene="yghU"
                     /locus_tag="ACL70N_000120"
     CDS             124011..124802
                     /gene="yghU"
                     /locus_tag="ACL70N_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGS0589018.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRQTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QENLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            124918..125328
                     /locus_tag="ACL70N_000121"
     CDS             124918..125328
                     /locus_tag="ACL70N_000121"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS0589019.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            125340..126935
                     /locus_tag="ACL70N_000122"
     CDS             125340..126935
                     /locus_tag="ACL70N_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589020.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            127102..127266
                     /locus_tag="ACL70N_000123"
     CDS             127102..127266
                     /locus_tag="ACL70N_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGS0589021.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            127345..128073
                     /gene="yaaA"
                     /locus_tag="ACL70N_000124"
     CDS             127345..128073
                     /gene="yaaA"
                     /locus_tag="ACL70N_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGS0589022.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(128351..128899)
                     /locus_tag="ACL70N_000125"
     CDS             complement(128351..128899)
                     /locus_tag="ACL70N_000125"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS0589023.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            129220..129729
                     /locus_tag="ACL70N_000126"
     CDS             129220..129729
                     /locus_tag="ACL70N_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGS0589024.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GLWNYPTVF"
     gene            129705..130892
                     /locus_tag="ACL70N_000127"
     CDS             129705..130892
                     /locus_tag="ACL70N_000127"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0589025.1"
                     /translation="MELSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            130885..131250
                     /locus_tag="ACL70N_000128"
     CDS             130885..131250
                     /locus_tag="ACL70N_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0589026.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            131266..132612
                     /gene="asnS"
                     /locus_tag="ACL70N_000129"
     CDS             131266..132612
                     /gene="asnS"
                     /locus_tag="ACL70N_000129"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGS0589027.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            132765..133055
                     /gene="rpsF"
                     /locus_tag="ACL70N_000130"
     CDS             132765..133055
                     /gene="rpsF"
                     /locus_tag="ACL70N_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGS0589028.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            133067..133537
                     /gene="ssbA"
                     /locus_tag="ACL70N_000131"
     CDS             133067..133537
                     /gene="ssbA"
                     /locus_tag="ACL70N_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGS0589029.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            133569..133808
                     /gene="rpsR"
                     /locus_tag="ACL70N_000132"
     CDS             133569..133808
                     /gene="rpsR"
                     /locus_tag="ACL70N_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGS0589030.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            134103..135503
                     /locus_tag="ACL70N_000133"
     CDS             134103..135503
                     /locus_tag="ACL70N_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGS0589031.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            135505..135864
                     /locus_tag="ACL70N_000134"
     CDS             135505..135864
                     /locus_tag="ACL70N_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGS0589032.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            135918..136667
                     /locus_tag="ACL70N_000135"
     CDS             135918..136667
                     /locus_tag="ACL70N_000135"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGS0589033.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            136657..136956
                     /locus_tag="ACL70N_000136"
     CDS             136657..136956
                     /locus_tag="ACL70N_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGS0589034.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            137027..137962
                     /locus_tag="ACL70N_000137"
     CDS             137027..137962
                     /locus_tag="ACL70N_000137"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGS0589035.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            138048..138560
                     /locus_tag="ACL70N_000138"
     CDS             138048..138560
                     /locus_tag="ACL70N_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGS0589036.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            138544..139193
                     /locus_tag="ACL70N_000139"
                     /pseudo
     CDS             138544..139193
                     /locus_tag="ACL70N_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            139294..139491
                     /locus_tag="ACL70N_000140"
     CDS             139294..139491
                     /locus_tag="ACL70N_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS0589037.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(139534..140979)
                     /locus_tag="ACL70N_000141"
     CDS             complement(139534..140979)
                     /locus_tag="ACL70N_000141"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGS0589038.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            141085..142707
                     /locus_tag="ACL70N_000142"
     CDS             141085..142707
                     /locus_tag="ACL70N_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS0589039.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEDSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            142910..144868
                     /locus_tag="ACL70N_000143"
     CDS             142910..144868
                     /locus_tag="ACL70N_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589040.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYRGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            145079..146133
                     /locus_tag="ACL70N_000144"
                     /pseudo
     CDS             145079..146133
                     /locus_tag="ACL70N_000144"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            146121..146714
                     /locus_tag="ACL70N_000145"
     CDS             146121..146714
                     /locus_tag="ACL70N_000145"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589041.1"
                     /translation="MRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVL
                     SGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQ
                     RLQIARTYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDV
                     DCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            146871..147965
                     /locus_tag="ACL70N_000146"
     CDS             146871..147965
                     /locus_tag="ACL70N_000146"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS0589042.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            147973..149139
                     /locus_tag="ACL70N_000147"
     CDS             147973..149139
                     /locus_tag="ACL70N_000147"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGS0589043.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            149232..152330
                     /locus_tag="ACL70N_000148"
     CDS             149232..152330
                     /locus_tag="ACL70N_000148"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0589044.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGLTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            152378..152995
                     /locus_tag="ACL70N_000149"
     CDS             152378..152995
                     /locus_tag="ACL70N_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS0589045.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            153006..154340
                     /gene="murC"
                     /locus_tag="ACL70N_000150"
     CDS             153006..154340
                     /gene="murC"
                     /locus_tag="ACL70N_000150"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGS0589046.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            154350..154814
                     /locus_tag="ACL70N_000151"
     CDS             154350..154814
                     /locus_tag="ACL70N_000151"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589047.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            154811..155305
                     /locus_tag="ACL70N_000152"
     CDS             154811..155305
                     /locus_tag="ACL70N_000152"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589048.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            155386..157041
                     /gene="mltG"
                     /locus_tag="ACL70N_000153"
     CDS             155386..157041
                     /gene="mltG"
                     /locus_tag="ACL70N_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGS0589049.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            157112..157594
                     /gene="greA"
                     /locus_tag="ACL70N_000154"
     CDS             157112..157594
                     /gene="greA"
                     /locus_tag="ACL70N_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGS0589050.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            157922..158320
                     /locus_tag="ACL70N_000155"
     CDS             157922..158320
                     /locus_tag="ACL70N_000155"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589051.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            158765..159772
                     /locus_tag="ACL70N_000156"
                     /pseudo
     CDS             158765..159772
                     /locus_tag="ACL70N_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            159847..160047
                     /locus_tag="ACL70N_000157"
     CDS             159847..160047
                     /locus_tag="ACL70N_000157"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGS0589052.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            160082..160798
                     /gene="atpB"
                     /locus_tag="ACL70N_000158"
     CDS             160082..160798
                     /gene="atpB"
                     /locus_tag="ACL70N_000158"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGS0589053.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQTIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            160812..161306
                     /gene="atpF"
                     /locus_tag="ACL70N_000159"
     CDS             160812..161306
                     /gene="atpF"
                     /locus_tag="ACL70N_000159"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGS0589054.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            161306..161842
                     /locus_tag="ACL70N_000160"
     CDS             161306..161842
                     /locus_tag="ACL70N_000160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGS0589055.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            161857..163362
                     /gene="atpA"
                     /locus_tag="ACL70N_000161"
     CDS             161857..163362
                     /gene="atpA"
                     /locus_tag="ACL70N_000161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGS0589056.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            163378..164256
                     /locus_tag="ACL70N_000162"
     CDS             163378..164256
                     /locus_tag="ACL70N_000162"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGS0589057.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            164342..165748
                     /gene="atpD"
                     /locus_tag="ACL70N_000163"
     CDS             164342..165748
                     /gene="atpD"
                     /locus_tag="ACL70N_000163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGS0589058.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            165759..166199
                     /locus_tag="ACL70N_000164"
     CDS             165759..166199
                     /locus_tag="ACL70N_000164"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGS0589059.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAKLRAERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(166244..167257)
                     /locus_tag="ACL70N_000165"
     CDS             complement(166244..167257)
                     /locus_tag="ACL70N_000165"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGS0589060.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            167401..168567
                     /locus_tag="ACL70N_000166"
     CDS             167401..168567
                     /locus_tag="ACL70N_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGS0589061.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            168557..169786
                     /locus_tag="ACL70N_000167"
     CDS             168557..169786
                     /locus_tag="ACL70N_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS0589062.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            169932..170573
                     /locus_tag="ACL70N_000168"
     CDS             169932..170573
                     /locus_tag="ACL70N_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0589063.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGVVTIISKKVEKKYSYYR"
     gene            170583..171212
                     /locus_tag="ACL70N_000169"
     CDS             170583..171212
                     /locus_tag="ACL70N_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0589064.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            171225..172061
                     /locus_tag="ACL70N_000170"
     CDS             171225..172061
                     /locus_tag="ACL70N_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589065.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
BASE COUNT        51425 a        31534 c        38656 g        50539 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttagatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggctcgt gtcgaagaaa atggtgagtt gacttggatc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttat ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgcgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 ttaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4621 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagccg tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgttatc
     4921 gatggtaatc gattgtttgg gaattgattt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg cgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gatgctttgg ttccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aagtttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttgacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ttcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7441 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctc attacgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctatattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa atgaataaaa gaggtcttta ttcaaaacta ggaatttctg
     8461 ttgtaggcat tagtctttta atgggagttc ctactttgat tcatgcgaat gaattaaact
     8521 atggtcaact gtccatatct cctatttttc aaggaggttc atatcaactg aacaataaga
     8581 gtatagatat cagctctttg ttattagata aattgtctgg agagagtcag acagtagtaa
     8641 tgaaatttaa agcagatgaa ccaaactctc ttcaagcttt gtttggccta tctaatagta
     8701 aagcaggctt taaaaataat tacttttcaa ttttcatgag agattctggt gagataggtg
     8761 tagaaataag agacgcccaa aagggaataa attatttatt ttctagacca gcttcattat
     8821 ggggaaagca taaaggacag gcagttgaaa atacactagt atttgtatct gattctaaag
     8881 ataaaacata cacaatgtat gttaatggaa tagaagtgtt ctctgaaaca gttgatacat
     8941 ttttgccaat ttcaaatata aatggtatag ataaggcaac actaggagct gttaatcgtg
     9001 aaggtaagga acattacctc gcaaaaggaa gtattgatga aatcagtcta tttaacaaag
     9061 caattagtga tcaggaagtt tcaaatattc ccttgtcaaa tccatttcag ttaattttcc
     9121 aatcaggaga ttctactcaa gctaactatt ttagaatacc gacactatat acattaagta
     9181 gtggaagagt tctatcaagt attgatgcac gttatggtgg gactcatgat tctaaaagta
     9241 agattaatat tgccacttct tatagtgatg ataatgggaa aacgtggagt gagccaattt
     9301 ttgctatgaa gtttaatgac tatgaggagc agttagttta ctggccacga gataataaat
     9361 taaagaatag tcaaattagt ggaagtgctt cattcataga ttcatccatt gttgaagata
     9421 aaaaatctgg gaaaacgata ttactagctg atgttatgcc tgcgggtatt ggaaataata
     9481 atgcaaataa agccgactca ggttttaaag aaataaatgg tcattattat ttaaaactaa
     9541 agaagaatgg agataacgat ttccgttata cagttagaga aaatggtgtc gtttatgatg
     9601 aaacaactaa taaacctaca aattatacta taaatgataa gtatgaagtt ttggagggag
     9661 gaaagtcttt aacagtcgaa caatattcgg ttgattttga tagtggctct ttaagagaaa
     9721 aacataatgg aaaacaggtc cctatgaatg ttttctacaa agattcgtta tttaaagtga
     9781 ctcctactaa ttatatagca atgacaacta gtcagaatag aggagagagt tgggaacaat
     9841 ttaagttgtt gcctccgttc ttaggagaaa aacataatgg aacttactta tgtcccggac
     9901 aaggtttagc attaaaatca agtaacagat tgatttttgc aacatatact agtggagaac
     9961 taacctatct catttctgat gatagtggtc aaacatggaa gaaatcctca gcttcaattc
    10021 cgtttaaaaa tgcaacagca gaagcacaaa tggttgaact gagagatggt gtgattagaa
    10081 cattctttag aaccactaca ggtaagatag cttatatgac tagtagagat tctggagaaa
    10141 catggtcgaa agtttcgtat attgatggaa tccaacaaac ttcatatggc acacaagtat
    10201 ctgcaattaa atactctcaa ttaattgatg gaaaagaagc agtcattttg agtacaccaa
    10261 attctagaag tggccgtaag ggaggtcaat tagttgttgg tttagtcaat aaagaagatg
    10321 atagtattga ttggaaatac cactatgata ttgatttgcc ttcgtatggt tatgcctatt
    10381 ctgcgattac agaattgcca aatcatcaca taggtgtgct gtttgaaaaa tatgattcgt
    10441 ggtcgagaaa tgaattgcat ttaagcaatg tagttcagta tatagatttg gaaattaatg
    10501 atttaacaaa ataaaggaga aaaaacatgg ttaaatacgg tgttgttgga gcagggtatt
    10561 ttggagctga attggctcgc tacatgcaaa agaatgatgg agcagagatt actcttctct
    10621 atgatccaga taatgcagag gcgattgcag aagaattggg agcaaaagta gcaagttcct
    10681 tagatgagtt ggtttctagc gatgaagtag attgtgttat cgtcgcaact ccaaataatc
    10741 ttcataagga accggttatt aaggctgcac agcatggtaa aaatgttttc tgtgaaaaac
    10801 caattgcgct ttcttatcaa gattgtcgcg agatggtaga tgcgtgtaaa gaaaacaatg
    10861 taacctttat ggcaggacat attatgaatt tctttaatgg tgttcatcat gcaaaagaac
    10921 tcattaatca aggagttatc ggagacgttc tatattgtca tacagctcgt aatggttggg
    10981 aagaacaaca accgtcagta tcatggaaaa aaattcgtga aaaatcaggt ggtcacttgt
    11041 atcaccacat ccatgaattg gattgcgttc aattccttat ggggggcatg cctgaaactg
    11101 taaccatgac aggtggaaat gtggcccatg aaggtgaaca tttcggtgat gaagatgata
    11161 tgatttttgt caatatggaa ttttctaata agcgttttgc cttgttagaa tggggttcag
    11221 cttatcgttg gggtgaacat tatgtcttaa tccaaggaag caaaggtgcc atccgcttag
    11281 acttattcaa ctgtaaagga actcttaagc tagatgggca agaaagctat ttcttgattc
    11341 acgaatcgca agaagaagat gatgatcgga ctcgtatcta tcatagtaca gagatggatg
    11401 gagcaattgc ttatggtaaa ccaggtaaac gtactccatt atggctatca tctgtcattg
    11461 ataaagaaat gcgctatctg catgagatta tggaaggagc cccagtatca gaagaatttg
    11521 caaaactttt gacaggtgaa gctgccctag aagcaattgc tactgcagat gcttgtaccc
    11581 agtctatgtt tgaagatcgc aaagtaaaat tgtcagaaat tgtaaaataa attttggtat
    11641 tctcctattt ataggtcgac ttgctcctct gaaagtactt ttagaggagc tgtttgactt
    11701 tgctagtttt tgaaactgaa atctattata ctacaaacta ttgaaagcgt tttaatttta
    11761 aggtataata atctcataga aataaagaaa aggaggaaag aggatgccac agattagcaa
    11821 agaagccttg attgagcaaa tcaaagatgg aatcatcgtt tcttgtcagg ctcttcctca
    11881 tgaaccgctt tatacagaag cgggaggggt gattcccttg ctggtcaaag cggctgagca
    11941 aggtggagca gtcggtatcc gagcaaacag tgttcgcgat atcaaggaaa ttaaggaagt
    12001 cactaaactt ccaatcattg ggattatcaa acgtgattat ccacctcagg aacccttcat
    12061 cacggctact atgaaagaag ttgatgaatt ggcagaactg gacatcgagg tgattgctct
    12121 ggattgtacc aagcgtgaac gctacgatgg tttggaaatt caagagttca ttcgtcaggt
    12181 taaggagaaa tatcctaatc agcttttgat ggctgatact agtatcttcg aagaagggct
    12241 agcagctgta gaagcaggaa ttgactttgt cggaacaacc ttatcaggct acacatccta
    12301 cagtccaaaa gtagacggtc cagattttga attgattaag aaactctgtg atgccggtgt
    12361 agatgtcatt gcagaaggaa aaattcatac accagaacaa gccaaacaaa tccttgaata
    12421 tggagtgcga ggcatcgttg ttggtggcgc cattactaga ccaaaagaga ttacagaacg
    12481 cttcgttgct agtcttaaat aagatgtgag agggagtttt atgtttaaag ttttacaaaa
    12541 agttggaaaa gcttttatgt tacctatagc tatacttcct gcagcaggtc tacttttggg
    12601 gattggtggt gcactttcaa acccaaccac gatagcaact tatccaatac tagacaatag
    12661 tatttttcaa tcaatattcc aagtaatgag ctctgcagga gaggttgtat tcagtaattt
    12721 gtcactactt ctctgtgtgg gattatgtat tggcttagcg aaacgagata aaggaaccgc
    12781 tgcgttagca ggagtaactg gttacttagt tatgactgca acgatcaaag ctttggtaaa
    12841 actttttatg gcagaaggat ctgcaattga tactggagtt attggagcat tagttgtcgg
    12901 aatagttgcc gtatatttgc acaaccgata taacaatatt caattacctt ccgctttagg
    12961 attctttgga ggttcacgct tcgttcctat tgttacatcg ttctcttcta tcttgattgg
    13021 ctttgtcttc tttgttattt ggccaccttt ccaacaactt cttgtttcta caggtggata
    13081 tatttctcag gcgggtccaa ttggaacttt tctatatgga tttttaatga gactttctgg
    13141 agcagtaggc ttacatcata taatttaccc tatgttttgg tatactgaac ttggtggtgt
    13201 tgaaactgtt gcaggacaaa cagtggttgg agctcaaaaa atattttttg ctcaattagc
    13261 cgatccggcc cattctggat tatttacaga aggaacaagg ttttttgcag gtcgtttctc
    13321 aacaatgatg ttcggtttac cggctgcctg tttagcgatg taccatagtg ttcctaaaaa
    13381 tcgtcgtaaa aaatacgcgg gtttgttttt tggagttgct ttaacatctt ttattaccgg
    13441 tattacagaa ccaattgaat ttatgtttct attcgtcagt ccggttctat atgttgttca
    13501 cgcattcctt gatggtgtta gcttctttat tgcagacgtc ttaaatattt caataggaaa
    13561 cacattttca ggaggtgtaa tcgatttcac tttatttgga attttgcagg ggaacgctaa
    13621 gacgaattgg gttcttcaga ttccaattgg acttatttgg agtgttttgt attatattat
    13681 ttttagatgg ttcattactc aattcaacgt tctaacgcca ggacgaggag aagaagtaga
    13741 ttctaaagaa atttctgaat ccgcagattc aacttcaaat actgcagatt atttaaaaca
    13801 ggatagccta caaattatca gagccttggg tggatcaaat aatatagaag atgtagatgc
    13861 ttgtgtgaca cgtttacgtg tagctgtaaa agaagttaat caagttgata aagcactttt
    13921 aaaacaaatt ggtgcagttg atgtcttaga agtgaagggt ggcattcaag caatctatgg
    13981 agcaaaagca atcttatata aaaatagtat taatgaaatt ttaggtgtag atgattaagt
    14041 acttactgac ttaataaaaa acagaggaga gtgatggatg agtaggatga aatgaaatcg
    14101 tatacaagaa ataaagaact cattatccaa gttggatacg cttattacat aggagaatac
    14161 aaatgaaatt tagaaaatta gcttgtacag tacttgcggg tgctgtggtt cttggtcttg
    14221 ctgcttgtgg caattctggc ggaagtaaag atgctgccaa atcaggtggt gacggtgcca
    14281 aaacagaaat cacttggtgg gcattcccag tatttaccca agaaaaaact ggtgacggtg
    14341 ttggaactta tgaaaaatca atcatcgaag cgtttgaaaa agcaaaccca gatataaaag
    14401 tgaaattgga aaccatcgac ttcaagtcag gtcctgaaaa aatcacaaca gccatcgaag
    14461 caggaacagc tccagacgta ctctttgatg caccaggacg tatcatccaa tacggtaaaa
    14521 acggtaaatt ggctgagttg aacgacctct tcacagatga atttgttaaa gatgtcaaca
    14581 atgaaaacat cgtacaagca agtaaagctg gagacaaggc ttatatgtat ccgattagtt
    14641 ctgccccatt ctacatggca atgaacaaga aaatgttaga agatgctgga gtagcaaacc
    14701 ttgtaaaaga aggttggaca actgatgatt ttgaaaaagt attgaaagca cttaaagaca
    14761 agggttacac accaggttca ttgttcagtt ctggtcaagg gggagaccaa ggaacacgtg
    14821 cctttatctc taacctttat agcggttctg taacagatga aaaagttagc aaatatacaa
    14881 ctgatgatcc taaattcgtc aaaggtcttg aaaaagcaac tagctggatt aaagacaatt
    14941 tgatcaataa tggttcacaa tttgacggtg gggcagatat ccaaaacttt gccaacggtc
    15001 aaacatctta cacaatcctt tgggcaccag ctcaaaatgg tatccaagct aaacttttag
    15061 aagcaagtaa ggtagaagtg gtagaagtac cattcccatc agacgaaggt aagccagctc
    15121 ttgaatacct tgtaaacggg tttgcagtat tcaacaataa agacgacaag aaagtcgctg
    15181 catctaagaa attcatccag tttatcgcag atgacaagga gtggggacct aaagacgtag
    15241 ttcgtacagg tgctttccca gtccgtactt catttggaaa actttatgaa gacaaacgca
    15301 tggaaacaat cagcggctgg actcaatact actcaccata ctacaacact attgatggat
    15361 ttgctgaaat gagaacactt tggttcccaa tgttgcaatc tgtatcaaat ggtgacgaaa
    15421 aaccagcaga tgctttgaaa gccttcactg aaaaagcgaa cgaaacaatc aaaaaagcta
    15481 tgaaacaata gtccttagtt attctataaa aagtagtttt ttaaagaacc taagagtgta
    15541 tacccccttt tccctctaca cagatagtgt aagaaaaggg ggcttttgtt taaaatgtaa
    15601 gaaactgtca cgaaattaaa atgaagttct tacataagcg aatcataaaa aatttcattt
    15661 tgattttaaa acagttcaag aaagtcaaaa aattattcta tttgaaagag aggtgccgac
    15721 tgtgaaagtc aataaaatcc gtatgcggga aacagtgatt tcctacgctt tcctagcacc
    15781 agtattattc ttctttgtca tctttgtgtt ggctccgatg gtgatgggct tcattacaag
    15841 tttctttaac tactcaatga ctaaatttga gtttgtaggc ttggataact atatccgtat
    15901 gtttaaagat cctgtcttta caaaatctct gattaacaca gttattttgg ttattggatc
    15961 tgtaccagtt gttgttctat tctcactctt tgtagcatct cagacctatc atcaaaatgt
    16021 cattgccaga tccttctacc gtttcgtctt cttccttcct gttgtaacgg gtagtgttgc
    16081 cgtgacagtt gtttggaaat ggatttatga cccactatca gggattctaa actttgtcct
    16141 taagtcaagc cacatcatca gccaaaacat ttcttggttg ggagataaaa actgggcatt
    16201 gatggcgatt atgattattc tcttgaccac ttcagttggt cagcccatca tcctttatat
    16261 cgctgccatg gggaatattg acaattcact ggttgaagcg gcgcgtgttg atggtgcaac
    16321 tgagtttcaa gttttttgga agattaaatg gccaagcctt cttccaacaa ctctttatat
    16381 tgcaatcatc acaacaatta actcattcca gtgtttcgcc ttgattcagc ttttgacatc
    16441 tggtggtcca aactactcaa caagtacctt gatgtactac ctttacgaaa aagccttcca
    16501 attgacagaa tacggctatg ccaacacaat tggtgtcttc ttggcagtca tgattgctat
    16561 cgtaagcttt gttcaattta aagtacttgg aaacgacgta gaatactaaa gaaaggagac
    16621 agctatgcaa tctacagaaa aaaaaccatt aacagccttt actgttattt caacaatcat
    16681 tttgctcttg ttgactgtgc tgttcatctt tccattctac tggattttga caggggcatt
    16741 caaatcacaa cctgatacaa ttgttattcc tcctcagtgg ttccctaaaa tgccaaccat
    16801 ggaaaacttc caacaactca tggtgcagaa ccctgccttg caatggatgt ggaactcagt
    16861 atttatctca ttggtaacca tgttcttagt ctgtgcaacc tcatctctag caggttatgt
    16921 attggctaaa aaacgtttct atggtcaacg cattctattt gctatcttta tcgctgctat
    16981 ggcacttcca aaacaagttg tccttgtacc attggtacgt atcgtcaact tcatgggaat
    17041 ccacgatact ctctgggcag ttatcttgcc tttgattgga tggccattcg gtgtcttcct
    17101 catgaaacag ttcagtgaaa atatccctac agagttgctt gaatcagcta aaatcgacgg
    17161 ttgtggtgag attcgtacct tctggagtgt agccttcccg attgtgaaac cagggtttgc
    17221 agcccttgca atctttacct tcatcaatac ttggaatgac tacttcatgc aattggtaat
    17281 gttgacttca cgtaacaatt tgaccatctc acttggggtt gcgaccatgc aggctgaaat
    17341 ggcaaccaac tatggtttga ttatggcagg agctgccctt gctgctgttc caatcgtcac
    17401 agtcttccta gtcttccaaa aatccttcac acagggtatt actatgggag cggtcaaagg
    17461 ataatactct gcgaaaatcg aatgcaaact acgtcagctt caccttgcca tacttaagta
    17521 ttgcctgtgg ttagcttcct agtttgttct tcaattttca ttgagtatag gaaaatcaat
    17581 ctatcaagat acagaagtat attttataga tttagagaat atagaagtta taagtgtcta
    17641 caaaatggag ggtatgcagt tactttatga agttttgtca gacacttatc aacttaagaa
    17701 tggttttagt taactatcag aaacgaagga aagagtatga tttttgacga tttgaaaaac
    17761 atcacctttt acaaagggat tcatcccaat ttagacaagg ctatcgacta cctctaccaa
    17821 catcgtaaag attcattcga attaggaaag tatgagattg atggagataa agtctttcta
    17881 gttgttcagg aaaatgtcct caatcaagtt gagaataatc aatttgaaca ccataagaac
    17941 tatgcagatt tgcatttgct gatagaaggg catgaatatt cgagctacgg ttcacgtatc
    18001 aaagacgagg cagtagcatt cgacgaagcg agtgacattg gctttgttca ttgttatgaa
    18061 cactacccac tcttattggg ttatcacaat tttgcgattt tcttcccagg tgagccacat
    18121 cagccaaatg gttatgcagg catggaagaa aaggttcgaa aatatctctt taaaatcttg
    18181 attgattaaa aataggatga attgtttttt tgtaaagctt tgataatact ctaccatgaa
    18241 attgatcttt gtgaggtaga gaaatgagaa taaaatattt aaaaattggt atcttctaag
    18301 tatgctgcaa gagctagttt cttggatgga cagggaatta cagttgatga gatggcttgg
    18361 ataattaggg gcattgtgaa tgcattgatt ggtagataca taaaattagg tgcttatgcg
    18421 gctaagtatg gtattagtat ggcacgctcg atcttaagta gggcagctgc aactgcagca
    18481 gcaagagtag gattatcgac caagatttct ggatggattt tacgagtagc tgtgaatgta
    18541 gctgatgtat atggtaattt tgcctacaat attgctgcag cttgggatgc acatgataaa
    18601 atccctaaca atggtcgtat aaacttttaa aatgcgagaa tgaaagcact ttgtattttt
    18661 ttattgaata tgttagcttg gacagtgctt gcaatgataa ttcgtggagg gctagatgga
    18721 tttaatgagc atacttggag tactatttta attgcttcgc tgttcggggt atatgattat
    18781 aagcccatag ataaaaatag aaaaaagtcc aaaagaaaaa agaaaaaata gatttgttca
    18841 tggtagggac ttatgaaagc tttactgaca aaaaagaaaa cagtttacaa agaaaaatga
    18901 tggaggagca aacatggcac aaaaaggagt aagccttatc aaggcagcat ttgatacaga
    18961 caactttctc atgcgtttta gtgagaaagt cttggacatc gtgacagcca atcttctttt
    19021 tgtcgtctct tgtttgccca tcgtgacgat tggagtggct aaaatcagcc tctacgagac
    19081 catgttcgaa gttaagaaga gcagacgggt gcctgttttt aaaatctatc taagatcttt
    19141 caagcaaaat ctgaaactag gtcttcagct gggtttaatg gagttaggaa ttgtgtttct
    19201 taccctttca gatctctatc ttttctgggg tcaaacagct ctgcccttcc aattgctgaa
    19261 agccatttgt ttaggtattc tgatttttct tactatcgtg atgctggcta gttaccctat
    19321 cgcggcacgt tatgacctat cttggaaaga aattcttcaa aaaggattga tgttggctag
    19381 ttttaacttt ccttggttct tcctcatgtt agccattctt gtcctcattg tgatggttct
    19441 ttatctgtcc gccttcagtc tactcttagg tggctcagtc ttcctacttt ttgggtttgg
    19501 actattggtc tttatccaga ctggattgat ggagaaaatt ttcgcaaaat accaatagga
    19561 gctttatttc tgaaactact ttcaaaggct ccaaacgcta ttctataagc gagaaactaa
    19621 aatctaagtg tctataagat attgaaagcc ttttcgggaa agtgtatact aaagaagtaa
    19681 agaaaaatct gctttagcag aaaataaaaa taataggaga aaatctatgt cagatttgaa
    19741 aaaatacgaa ggtgtcattc cagccttcta cgcatgttat gatgatcaag gagaagtaag
    19801 cccagaacgt acgcgtgcct tggttcaata cttcattgat aaaggtgttc aaggtcttta
    19861 tgtcaatggt tcttctggtg aatgtatcta ccaaagcgtt gaagatcgca agttgatttt
    19921 ggaagaagtc atggcggtag ccaaaggtaa attgaccatc attgctcatg ttgcctgcaa
    19981 caatactaaa gacagtatgg aacttgctcg ccatgctgaa agcttgggag tagatgctat
    20041 tgcaacgatt ccaccaattt acttccgctt gccagaatac tcagttgcca aatactggaa
    20101 cgatatcagt tctgcagctc caaacacaga ctacgtgatt tacaacattc ctcaattggc
    20161 aggggttgct ttgactccaa gcctttacac agaaatgttg aaaaatcctc gtgttatcgg
    20221 tgttaagaac tcttctatgc cagttcaaga tatccaaacc tttgtcagcc ttggtgggga
    20281 agaccatatc gtctttaacg gtccagatga acagttccta ggtggccgcc tcatgggtgc
    20341 taaggctggt atcggtggta cttatggtgc tatgccagaa ctcttcttga aactcaatca
    20401 gttgattgcg gataaggacc tagaaacagc gcgtgaattg cagtatgcta tcaacgcaat
    20461 cattggtaaa ctcacttctg ctcatggaaa tatgtacggt gtcattaaag aagttttgaa
    20521 aatcaatgaa ggcttgaata ttggatctgt tcgttcacca ttgacaccag tgactgaaga
    20581 agatcgtcca gttgtagaag cggctgctgc cttgattcgt gaaaccaagg agcgcttcct
    20641 ctaatctaaa aggaggtatt tatgacatac tacgttgcaa ttgatatcgg tggaaccaac
    20701 atcaagtatg gtttggttga tcaagagggg caacttcttg aatcgcatga aatgccaact
    20761 gaggcgcata agggtggacc tcatatctta caaaagacca aagatatcgt agctagttat
    20821 ttagaaaaag gcctagtagc aggtgttgcc atatcttctg ctgggatggt ggatccggat
    20881 aagggtgaga ttttctatgc tgggccgcaa atccctaact acgcaggcac ccagttcaaa
    20941 aaggaaatcg aagaaagctt tactattcct tgtgagattg aaaatgatgt caactgtgca
    21001 ggtcttgctg aggcagtatc tggttcaggc aagggagcaa gtatgacact ttgcttgacc
    21061 attggaacag gtatcggtgg ttgcttgatt atggatagga aagtcttcca tggttttagc
    21121 aattcagcct gtgaagtcgg gtatatgcat atgcaggatg gagcttttca agacttggct
    21181 tctacaacag ctttagtgaa atatgtagct gaagcccatg gagaagatgt tgatcagtgg
    21241 aatggccgta gaattttcaa agaagccact gaaggaaaca aaatctgcat ggaaggtatt
    21301 gaccgtatgg ttgactatct aggaaaaggt ctggcaaata tttgctacgt tgccaatcca
    21361 gaagtggtta ttcttggtgg tggtatcatg gggcaagagg ctatcctcaa acctaagatt
    21421 cgcacagcct tgaaagaggc tttggtacca agtttagcag aaaaaacacg attagaattt
    21481 gcccatcacc aaaatacagc agggatgttg ggtgcatatt atcattttaa gacaaaacaa
    21541 tcctagtttg gctcagccaa actaggattt tcttacacgt ttttgtctac gatagccgtt
    21601 gagtttttta ttttcccagt agctattaaa gattttttcc ttgctttcgc gattgatttc
    21661 caaaaagtag gcataaatca aatcgataaa gaagagcata ggaagttgag cggatattcg
    21721 ttggatatag gagggttggc tgtgggtggc tacaagaaca gtctctgtat aggtctggct
    21781 atttttattg ggaacacttg taaagagtac agtctttgcc cccatctcct tggcatctaa
    21841 tagactatct aaaatagaag gagttgagcc tgaaagtgag aagcccagta ctagacaatt
    21901 ttcatccatg atgctggttg tccaggcaaa gccgtcttgg tctgtcaaag cttcgcagac
    21961 cacgcctagt cgcataaaac gtaatttcat ttcacgggcg acgagaccag aactccctgt
    22021 tccaaagaag tagatacgct cagcatcttc gattagctgg gcaattcgtt ctagttggat
    22081 ttcgtcaatc aagtcttgtg tttgttccct catattgcta taacttctga ggactcgttt
    22141 ggtcagtgga ctgtgcttgg agacttggtt ggcttgattt tctgcctgat gttggtattg
    22201 gaaaataaat tctcggtagc cagtaaagcc acacttttta gcaaagcggg tcaaagcagc
    22261 ttgagaaata tgtaattttt gggtgacttg ttgagaagat aaatcatctg taatcgtttc
    22321 agcttgcaaa aaatagcgag cgatttcttg ctctaggtct gtcatttctt caaaatgtga
    22381 atcaatgata gttgcgatat ctggtttgtc catagggaaa gctcctttac atgagtcata
    22441 ctggaagact agatcaggga atagtcacac ttcattataa cacataatat aaggatagat
    22501 aaataaaaac gcatttctgt tttaaaaacg aaaaaatcga aaaagcttct ctcttttcca
    22561 taattttcta ctcaaattgt ggtacaatta agagtaagat tttaagttag aaatgagact
    22621 gatttgtatg agaaaattta acagccattc gattccgatt cggcttaatt tattgttttc
    22681 aatcgtcatt ttactcttta tgaccattat tggtcgtttg ttgtatatgc aggttttgaa
    22741 caaggatttt tacgaaaaaa agctagcctc agctagtcag accaagatta caagcagttc
    22801 agcccgtggg gaaatttatg atgctagtgg aaaacctttg gtagaaaata cgttaaagca
    22861 ggttgtttcc tttacgcgta gcaataaaat gacggctaca gacttaaaag aaacagctaa
    22921 aaagttactg acttatgtga gcatcagttc tccaaatttg acagaacgcc agctggcgga
    22981 ttactatttg gctgatcctg aaatctataa aaaaacagtg gaagctctcc caagcgagaa
    23041 acgcttggat tcagatggaa atcgtctatc cgaatcagaa ctgtataaca atgcggtcga
    23101 tagtgtccaa acaagtcaac taaactatac agaggatgaa aagaaagaaa tctatctttt
    23161 tagtcagtta aatgctgttg gaaactttgc gacaggaacc attgctacag atcctctaaa
    23221 tgattctcag gtggctgtta ttgcctctat ttcaaaggag atgcctggca ttagtatttc
    23281 gacttcttgg gatagaaagg ttttggaaac ttccctttct tctatagttg ggagtgtatc
    23341 cagtgaaaaa gctggtctcc cagcggaaga agcagaagcc tatcttaaaa aaggctattc
    23401 tctaaatgac cgtgtaggaa cctcctattt ggaaaagcaa tatgaagaga ccttacaagg
    23461 aaaacgatcg gtaaaagaaa tccatctgga taaatatggc aatatggaaa gcgtggatac
    23521 aattgaggaa ggtagtaagg gaaacaatat caaactgacc attgatttgg ccttccaaga
    23581 tagcgtggat gctttgctga aaagttattt caattctgag ctagaaaatg gtggagccaa
    23641 gtattctgaa ggtgtctatg cagtcgccct taacccaaaa acaggtgcgg ttttgtctat
    23701 gtcagggatt aaacatgact tgaaaacagg agagttgacg cctgattcct tgggaacggt
    23761 aaccaatgtc tttgttccag gttcggttgt caaggcggcg accatcagct caggttggga
    23821 aaatggagtc ttgtcaggaa accagacctt gacagaccag tccattgtct tccaaggttc
    23881 agctcccatc aattcttggt atactcaggc ttacggttca ttccctatca cagcggtcca
    23941 agctctggag tattcatcaa atacctatat ggtccaaaca gccttaggtc ttatggggca
    24001 aacctatcaa cccaatatgt ttgtcggcac cagcaatcta gagtctgcta tggagaaact
    24061 gcgttcaacc tttggcgaat atggcttggg tactgcgaca ggaattgacc taccagatga
    24121 atctactgga tttgttccca aagagtatag ctttgctaat tacattacta atgcctttgg
    24181 gcagtttgat aactatacgc cgatgcagtt ggctcagtat gtagcaacta ttgcaaatga
    24241 tggtgttcgt gtggctcctc gtattgttga aggcatttat ggtaataatg ataagggagg
    24301 actgggtgac ttgattcagc aactgcaacc gacagagatg aataaggtca atatatccga
    24361 ctccgatatg agcatcttgc accaaggttt ttatcaggtt gcccatggta ctagtgaatt
    24421 gacaactgga cgtgcctttt caaatggtgc cttggtatcc attagcggaa aaacaggtac
    24481 agccgaaagc tatgtggcag atggtcagca agcaaccaat accaatgcgg tggcctatgc
    24541 cccatctgat aatccccaaa tcgctgtcgc agtggtcttt cctcataata ccaatctaac
    24601 aaatggtgta ggaccttcca ttgcacgtga cattatcaat ctgtatcaaa aataccatcc
    24661 aatgaactag aaaggaaatt atgctttatc caacacctat tgccaagttg attgacagtt
    24721 attctaagtt accaggtatc gggattaaga cggctacgcg tctggccttt tatacgattg
    24781 ggatgtctgc tgatgatgtc aatgaatttg caaaaaatct cctttctgct aagagagaat
    24841 tgacatattg ttctatttgt ggacgtttga cagacgacga tccttgttct atctgtactg
    24901 atccgactcg tgaccagaca acaattttag ttcttgagga tagtagagat gtggcagcca
    24961 tggaaaatat ccaagaatac catggactct atcatgtcct tcatggcctc atttctccta
    25021 tgaatggtat cagtccggac gatatcaatc tcaagagcct tatgactcgt cttatggata
    25081 gtgaggtttc agaagtgatt gtggcgacta atgctacagc ggatggtgaa gcgacttcca
    25141 tgtatctttc acgtttgctc aagccggctg gtatcaaggt tacgcgtcta gcacgaggtc
    25201 tcgctgtggg agcggacatt gagtatgcgg acgaagtgac actcttacga gccattgaaa
    25261 atcggacaga gttgtaagtg taggcaaatt tacgaactcc attcatttat aaaaaatcaa
    25321 agaggctgga aatcgttcct atcggcctct ttttgtatag tgtgatgagt aggatcaggt
    25381 tcaagtttta aaaaaccaag caaatatgat atactaaaga gcgagtattc tagtagaatt
    25441 aggacaaata atatgaaaca aacgattatt cttttatatg gtggacggag tgcggaacgc
    25501 gaagtctctg tcctttcagc tgagagtgtc atgcgtgcgg tcgattacga ccgcttcaca
    25561 gtcaagactt tctttatcag tcagtcaggt gactttatca aaacacagga atttagtcat
    25621 gctccggggc aagaagaccg tctcatgacc aatgaaacca ttgattggga taagaaagtt
    25681 gcaccaagtg ctatctacga agaaggtgca gtggtctttc cagtccttca cgggccaatg
    25741 ggagaagatg gctctgttca aggattcttg gaagttttga aaatgcctta cgttggttgc
    25801 aacattttgt catcaagtct tgccatggat aaaatcacga ctaagcgtgt tctggaatct
    25861 gctggtattg cccaagttcc ttatgtggct atcgttgaag gcgatgatgt gactgctaaa
    25921 atcgctgaag tggaagaaaa attggcttat ccagtcttca ctaagccgtc aaacatgggg
    25981 tctagtgtcg gtatttctaa gtctgaaaac caagaagaac tccgtcaagc cttagaactt
    26041 gccttccgat atgatagccg tgtcttggtt gagcaaggag tgaatgcccg tgaaattgag
    26101 gttggcctct tgggtaacta cgatgtcaag agcacgctac caggagaagt tgtcaaggac
    26161 gttgcctttt atgactacga tgccaagtat attgataaca agattactat ggatattcct
    26221 gccaaaatca gtgatgatgt ggtggctgtc atgcgtcaaa atgcagaaac agccttccgt
    26281 gccattggtg gccttggtct atctcgttgc gatttcttct atacagataa gggagagatt
    26341 tttctcaacg agctcaatac catgccaggt ttcacccagt ggtctatgta cccactactt
    26401 tgggacaata tggggatcag ctacccagaa ctaatcgagc gtttggttga ccttgccaag
    26461 gaaagttttg acaagcgcga agcgcatttg atataaaatg aaagagaggg tagaagccag
    26521 aaccatcact gcaaggtgac tagagttctc ggacttcagc cctttttaaa ggagtagaaa
    26581 tgaaattaac aatccatgaa attgcccaag ttgttggagc caaaaatgat atcagtatct
    26641 ttgaggacac ccagttagaa aaagctgagt ttgatagtcg tttgattgga actggagatt
    26701 tatttgtgcc acttaaaggt gcgcgtgatg gccatgactt tattgaaaca gcctttgaaa
    26761 atggtgcagc agtaaccttg tctgagaaag aggtctcaaa tcatccttac attctagtag
    26821 atgatgtttt gacagccttt caatccctag catcctacta tcttgaaaaa acgactgttg
    26881 atgtctttgc tgttacaggt tcaaatggca agacaacgac taaggatatg ttggcgcatt
    26941 tactgtcaac aagatacaag acctacaaaa cacaaggcaa ttacaataac gagattggcc
    27001 ttccttacac agttcttcat atgcctgaag ggacagaaaa gttggtcttg gagatggggc
    27061 aggatcactt gggagatatt catctcttgt ctgaactggc tcgtccaaaa acagccatcg
    27121 tgaccttggt tggagaagct catttggcct ttttcaaaga tcgttctgag attgctaaag
    27181 gaaaaatgca aattgcggac ggaatggctt caggttcctt gcttttagcg ccggctgacc
    27241 ctatcgtaga ggactatttg ccaactgata aaaaagtggt tcgttttggg caaggggcag
    27301 agctggaaat tactgacttg gttgagcgca aagatagtct gaccttcaag gccaatttct
    27361 tagagcaagc ccttgatttg ccagtaactg gtaagtacaa tgctaccaat gctatgattg
    27421 catcctatgt tgccctacaa gaaggagttt cagaggagca aatccgtttg gccttccaag
    27481 gtcttgaatt gacgcgtaat cgtactgagt ggaagaaagc agccaatgga gcagatatcc
    27541 tgtcagacgt atataatgcc aatccaactg ctatgaagct gattttagag actttctctg
    27601 ccattccagc caatgaaggt ggcaagaaaa ttgcagtgtt ggcggatatg aaggagcttg
    27661 gtgaccagtc tattcaactc cataaccaga tgattttgag cctttcgcca gatgtgcttg
    27721 ataccgttat tttctatgga gaagacattg ctgaattagc ccaattggcc agtcaaatgt
    27781 tcccaattgg ccacgtttac tacttcaaga aaacagaaga ccaagaccaa tttgaagacc
    27841 tagtcaagca ggtcaaggaa agcctcagtg ccaatgatca aatcttgctc aagggctcta
    27901 actctatgaa cctagccatg ttggtagaaa gtttagaaaa tgaaaccaag tgattttgtt
    27961 aagtatctgc aaagaatgat tgcccttaca gatactggct taacctttac aaaagatcct
    28021 tttgaccgtg agcgctacga ggacttgcga agtctgttat ctgaaatgtt gaatcaggga
    28081 tcagacctgg atgcagaaga agtagcagaa gtcttgaaac caacttcagc ttatgcgact
    28141 cccttaatgg acgtccgtgc ttggattgtt gaggatgaga agatttgtct ggttagggga
    28201 caaggagagg atagttgggc tttgccaggt ggctttggtg aagtcggcta ttctccaact
    28261 gaaaatattc tcaaggaaat tgaagaagaa accggtttta aagccaaagt tgaaagactg
    28321 ctagctgttt ttgataccaa tcgtttccaa ctacagagca aacaatatgc aaagtttgtt
    28381 tttgaatgta agcttctcga tggacaattc caagaaaatc aagaaatcgc tgaccttcaa
    28441 ttttttgcaa ttgaccaact gccgaattta tctgaaaaac gcattaccaa ggagcaaata
    28501 gagcttcttt ggcaggttta tcaaggtcag agggagcaat atcttgacta agaagatgat
    28561 tatcgtattt ctaaattcat ttttcttaag tagcatggta taataaaatg caggaaaatt
    28621 ttgaatcatg aggaagacta gatgaattta tgggatattt tctttacgac tcaggcaacc
    28681 gagccgccca aatttgacct tttttggtat gttagcctat ttacgctctt agccttaacc
    28741 ttttatacag cccatcgcta tcgtgaaaag aaggtttacc aacgattttt ccaaatcttg
    28801 cagactgttc agttaatcct tctttatggt tggtactggg tcaatcatat gccactgtca
    28861 gaaagcctac ccttttacca ttgccgtatg gctatgtttg tggtactctt gcttcctggt
    28921 cagtccaaat ataaacaata ctttgcatta ttgggaacat ttgggacatt agcagccttt
    28981 gtttatccag tgccagatgc ttaccctttt ccacatatca ccattctatc ctttatcttt
    29041 ggtcatttag cactcttggg gaactctcta gtttatctat tgagacagta taatgcgcga
    29101 ttgctggatg tgaagggaat ttttctcatg acctttgccc taaatgcctt gatttttgtg
    29161 gtcaatttgg tgacaggtgg cgattacgga tttttgacaa aaccgccatt ggttggggat
    29221 cacggtctag tagctaatta tttacttgtt tcaattgtgc tggtagctac tatcagtttg
    29281 actaagaaaa tcttagaatt ctttttagct caagaagcag aaaaaatgat tgcaaaggaa
    29341 gcttaacaca gagctttctt ttttgctctt agagagtttt tacaagcagc ttataaaata
    29401 agaatttctg aatagacaaa ctcaaaaaat ggctgggaaa tttaggaaaa aagcaagcac
    29461 gattaaattt tttgtgttat aatattttgt gaatagctat gcctatgttt agctatggaa
    29521 taatacgaag tgcgaaactt ggaagataga gaggaagcga tgtaatggct agagaaggct
    29581 tttttacagg tctagatatt ggaacaagct ctgtcaaggt gcttgtggcc gagcagagaa
    29641 ctggtgaatt aaatgtaatt ggcgtgagta atgccaaaag taaaggtgta aaggatggaa
    29701 ttattgttga tattgatgca gcagcaactg ctatcaagtc agccatttcc caagcggaag
    29761 aaaaggcagg catttcgatt aaatcagtaa atgtcggctt gcctggtaat cttttgcagg
    29821 tagaaccaac tcaggggatg attccagtaa catctgatac taaggaaatt acggatcaag
    29881 atgttgaaaa tgttgtcaaa tcagctttga caaagagtat gacacctgac cgtgaagtca
    29941 ttacctttat tcctgaagaa tttattgtgg atggtttcca agggattcgt gacccacgtg
    30001 gcatgatggg ggttcgcctt gaaatgcgtg gtttgcttta tacaggacct cgtactatct
    30061 tgcacaattt gcgtaagacg gttgagcgtg caggtgttca ggttgaaaat gttatcattt
    30121 caccactagc aatggttcag tctgttttga acgaagggga acgtgaattt ggtgctacag
    30181 tgattgatat gggggcaggt caaacgactg tcgctacaat ccgtaatcaa gaactccagt
    30241 tcacacatat tctccaagaa ggtggagatt atgtaactaa agatatctcc aaggttttga
    30301 aaacctctcg caaattagcg gaaggcttga aactgaatta cggggaagcc tatccgcctc
    30361 ttgcaagcaa agaaaccttc caagtagagg ttattggaga agtagaagca gtcgaagtga
    30421 cggaagccta cttgtcagaa attatttctg cacgaatcaa gcacatcctt gaacaaatca
    30481 agcaagaatt agatagaagg cgtctattgg acctccctgg tggtattgtc ttaatcggtg
    30541 ggaatgccat tttaccaggt atggttgagc ttgctcagga agtctttggc gtccgtgtca
    30601 agctttatgt tccaaatcaa gttggtatcc gtaatccagc ctttgcgcat gtgattagtt
    30661 tatcagaatt tgcgggtcaa ttaacagaag ttaatctttt ggctcaggga gcgataaaag
    30721 gtgagaatga cttaagtcat cagccaatta gttttggtgg gatgctgcaa aaaacagctc
    30781 agtttgtaca atcaacgcct gttcaaccag ctcctgctcc agaagtagag ccggtggcgc
    30841 ctacagaacc aatggcggat ttccaacaag cttcacaaaa taaaccgaaa ttagcagatc
    30901 gtttccgtgg cttgatcgga agcatgtttg acgaataaag aggaaaaata aattatgaca
    30961 ttttcatttg atacagctgc tgctcaaggg gcagtgatta aagtaattgg tgtcggtgga
    31021 ggtggtggca atgccatcaa ccgtatggtc gacgaaggtg ttacaggcgt agaatttatc
    31081 gcagcaaaca cagatgtaca agcattgagt agtacaaaag ctgagactgt tattcagttg
    31141 ggacctaaat tgactcgtgg tttgggtgca ggaggtcaac ctgaggttgg tcgtaaagcc
    31201 gctgaagaaa gcgaagaaac actgacggaa gctattagtg gtgccgatat ggtcttcatc
    31261 actgctggta tgggaggagg ctctggaact ggagctgctc ctgttattgc tcgtatcgcc
    31321 aaagatttag gtgcgcttac agttggtgtt gtaacacgtc cctttggttt tgaaggaagt
    31381 aagcgtggac aatttgctgt agaaggaatc aatcaacttc gtgagcatgt agacactcta
    31441 ttgattatct caaacaacaa tttgcttgaa attgttgata agaaaacacc gcttttggag
    31501 gctcttagcg aagcggataa cgttcttcgt caaggtgttc aagggattac cgatttgatt
    31561 accaatccag gattgattaa ccttgacttt gccgatgtga aaacggtaat ggcaaacaaa
    31621 gggaatgctc ttatgggtat tggtatcggt agtggagaag aacgtgtggt agaagcggca
    31681 cgtaaggcaa tctattcacc acttcttgaa acaactattg acggtgctga ggatgttatc
    31741 gtcaacgtta ctggtggtct tgacttaacc ttgattgagg cagaagaggc ttcacaaatt
    31801 gtgaaccagg cagcaggtca aggagtgaac atctggctcg gtacttcaat tgatgaaagt
    31861 atgcgtgatg aaattcgtgt aacagttgtc gcaacgggtg ttcgtcaaga ccgcgtagaa
    31921 aaggttgtgg ctccacaagc tagatctgct actaactacc gtgagacagt gaaaccagct
    31981 cattcacatg gctttgatcg tcattttgat atggcagaaa cagctgaatt gccaaaacaa
    32041 aatccacgtc gtttggaacc aactcaggca tctgcttttg gtgattggga tcttcgccgt
    32101 gaatcgattg ttcgtacaac agattcagtc gtttctccag tcgagcgctt tgaagcccca
    32161 atttcacaag atgaagatga attggataca cctccatttt tcaaaaatcg ttaagtaaat
    32221 gaatgtaaaa gaaaatacag aacttgtttt tcgagaagtt gcagaggcta gtctgagtgc
    32281 tcatcgagag agtggttcgg tctctgtcat tgcagttacc aagtatgtag atgtaccgac
    32341 agcggaagcc ttgcttccgc taggtgttca tcatatcggt gaaaatcgtg tagataagtt
    32401 tctggaaaaa tatgaagctt taaaagatcg agatgtgact tggcatttga ttggtacctt
    32461 gcaaagacgt aaggtgaaag atgtcattca atacgttgat tatttccatg cattggactc
    32521 agtaaagcta gcaggggaaa ttcaaaaaag aagtgaccga gtcatcaagt gtttccttca
    32581 agtaaatatt tctaaagaag aaagcaaaca cggtttttcg agagaggaac tgctggaaat
    32641 cttgccagag ttagccagac tagataagat tgaatatgtt ggtttaatga cgatggcacc
    32701 ttttgaggct agcagtgagc agttgaaaga gattttcaag gcgacccaag atttacaaag
    32761 agaaattcaa gagaaacaaa ttccaaatat gcctatgacc gagttaagta tgggaatgag
    32821 tcgtgattat aaagaagcga ttcaattcgg ttccactttt gttcgtatag gtacatcatt
    32881 ttttaagtag gagagaacca tgtctttaaa agatagattc gatagattta tagattattt
    32941 tacggaggat gaggattcaa gtctccctta tgaaaaaaga gatgagcctg tgtttactcc
    33001 agtaaattct tcacaggaac cggctctccc aatgaatcaa ccttcacagt cggctggtac
    33061 aaaagagaac aatatcacca gacttcatgc aagacaacag gaattggcaa atcagagtca
    33121 gcgtgcaacg gataaggtca ttatagatgt tcgttatcct agaaaatatg aggatgcaac
    33181 agaaattgtt gatttattgg caggaaacga aagtatcttg attgattttc agtatatgac
    33241 agaggtgcag gctcgtcgtt gtttggacta tttggatgga gcttgtcatg ttttagctgg
    33301 aaatttgaaa aaggtagctt ctaccatgta tttgttgaca ccagtgaatg ttattgtaaa
    33361 tgttgaagat atccgtttac cagatgaaga tcaacagggt gagttcggtt ttgatatgaa
    33421 gcgaaataga gtacgataat gattttttta attcgtatga tttataatgc agtggatatt
    33481 tactccctga ttttggtagc cttcgctgtc atgtcttggt ttccaggtgc ctacgaatcc
    33541 agtttaggtc gttggattgt agcgttggtg aaaccagtgc ttgctccctt gcaacgcctg
    33601 cctttacaga tagcgggtct tgatttatct gtttgggtcg cgattgtttt ggttcgattt
    33661 ttaggagaaa acctagtgcg ttttctggcg atgataggat gaataaaggg atttattagc
    33721 atttctccat agaagatcgt ccatttcttg acaagggaat ggaatggata aagaaggtag
    33781 aagatagcta tgctcctttt ttaactcctt ttatcaatcc tcatcaggag aagctattaa
    33841 agattttggc caaaacctat ggtcttgctt gtagcagtag tggggaattc gtctcgagtg
    33901 agtatgttcg agttttatta tacccagatt atttccaacc agagttttca gattttgaaa
    33961 tatctctcca ggaaattgtg tattccaata aatttgaaca tttaacgcat gctaagattt
    34021 tagggacagt catcaatcaa ttagggattg aacggaaact ttttggagat atcctagtag
    34081 atgaagaacg ggcgcagatt atgattaatc agcagtttct tcttctcttt caagatggac
    34141 taaagaaaat tggtcgtata cctgtttcgc tggaggaacg tcctttcacc gagaaaatag
    34201 ataagctaga acagtatcga gaactggatt tatctgtgtc tagttttcga ttagatgttc
    34261 ttttatcaaa tgttttgaaa ctatctagga atcaagcaaa ccagttgatt gaaaagaaac
    34321 ttgtccaagt aaattatcat gtggtagaca aatcagatta cactgttcaa gttggagact
    34381 tgattagtgt gagaaaattt ggtcgcttga gattacttca agataaggga caaacgaaaa
    34441 aagagaagaa aaaaataacc gtccagttat tattaagtaa gtgaggaata gaatgccaat
    34501 tacatcatta gaaataaagg acaagacttt tggaactcga ttcagaggtt ttgatccaga
    34561 agaagtcgat gaatttttag atattgtggt tcgtgattac gaagatcttg tgcgtgcgaa
    34621 tcatgataaa aatttgcgta ttaagagttt agaagagcgt ttgtcttact ttgatgaaat
    34681 aaaagattca ttgagccagt ctgtattgat tgctcaggat acagctgaga gagtgaaaca
    34741 ggcggcgcat gaacgttcaa acaatatcat tcatcaagca gagcaagatg cgcaacgctt
    34801 gttggaagaa gctaaatata aggcaaacga gattcttcgt caagcaactg ataatgctaa
    34861 gaaagtcgct gttgaaacag aagaattgaa gaacaagagc cgtgtcttcc accaacgtct
    34921 caaatctaca attgagagtc agttggctat tgttgaatct tcagattggg aagatattct
    34981 ccgtccaaca gctacttatc ttcaaaccag tgatgaagcc tttaaagaag tggttagcga
    35041 agtacttgga gaaccgattc cagttccaat tgaagaagaa ccaattgata tgacacgtca
    35101 gttctctcaa gcagaaatgg aagaattaca agctcgtatt gaggtagccg ataaagaatt
    35161 gtctgaattt gaagctcaga ttaaacagga agtggaagct ccaactcctg tagtgagtcc
    35221 tcaagttgaa gaagagcctc tgctcatcca gttggcccaa tgtatgaaga accagaagta
    35281 gctccagtgc atccgacagg tccaacacca gctacagaaa ctgttgattc agcaccggga
    35341 tttgaagcac cgcaagaatc tgttacaatt ttataagaaa tattctgaga acaatatctt
    35401 atccttatat tcccagcgag caggagatgg tgtgagtcct gcattcccta tcgataagat
    35461 tatcctctca aaaactcaag tctgaatcta gtaagatttg acgttcccca cgttacggga
    35521 taagagggag aaagactaaa actttttccg aataaaggtg gtaccacgat tttcgtcctt
    35581 tttggaagtt gtggttttta atttgttatt atttataaag gagataccat gaaactcaaa
    35641 gacaccctta atcttgggaa aactgaattc ccaatgcgtg caggccttcc taccaaagag
    35701 ccagtttggc aaaaggaatg ggaagatgca aaactttatc aacgtcgtca agaattgaac
    35761 caaggaaaac ctcatttcac cttgcatgat ggccctccat acgctaacgg aaatatccac
    35821 gttggacatg ctatgaacaa gatttcaaaa gatattattg ttcgttctaa gtctatgtca
    35881 ggattttacg caccatttat tcctggttgg gatactcatg gtctgccaat cgagcaagta
    35941 ttgtcaaaac aaggtgtcaa acgtaaagaa atggacttgg ttgagtactt gaaactttgc
    36001 cgtgagtacg ctctttctca agtagataaa caacgtgaag attttaaacg tttgggtgtt
    36061 tctggtgact gggaaaatcc atatgtgacc ttgactcctg actatgaagc agctcaaatt
    36121 cgtgtatttg gtgagatggc taataagggt tatatctacc gtggtgccaa gccagtttac
    36181 tggtcatggt catctgagtc agcccttgct gaagcagaga ttgaatacca tgacttggtt
    36241 tcaacttccc tttactatgc caacaaggta aaagatggca aaggagttct agatacagat
    36301 acttatatcg ttgtctggac aacgactcca tttaccatca cagcttctcg tggtttgacg
    36361 gttggtgcag atattgatta cgttttggtt caacctgctg gtgaagctcg taagtttgtc
    36421 gttgctgctg aattattgac tagcttgtct gagaaatttg gctgggctga tgttcaagtt
    36481 ttggaaactt accgtggcca agaactcaac cacatcgtaa cagaacaccc atgggataca
    36541 gctgtagaag agttggtaat tcttggtgac cacgttacga ctgactctgg tacaggtatt
    36601 gttcatacag cccctggttt tggtgaggac gattacaatg ttggtattgc taataatctt
    36661 gaagtcgcag tgactgttga tgaacgtggt atcatgatga agaatgctgg tcctgaattt
    36721 gaaggtcaat tctatgaaaa ggtagttcca actgtgattg aaaaacttgg taacctcctt
    36781 cttgcccaag aagaaatctc tcactcatat ccatttgact ggcgtactaa gaaaccaatc
    36841 atctggcgtg cagttccaca atggtttgcc tcagtttcta aattccgtca agaaatcttg
    36901 gacgaaattg aaaaagtgaa attccactca gaatggggta aagtccgtct ttacaatatg
    36961 atccgtgacc gtggtgactg ggttatctct cgtcaacgtg cttggggtgt tccacttcct
    37021 atcttctacg ctgaagatgg tacagctatc atggtagctg aaactattga acacgtagct
    37081 caactttttg aagaacatgg ttcaagcatt tggtgggaac gtgatgccaa agacctcttg
    37141 ccagaaggat ttactcatcc aggttcacca aacggcgagt tcaaaaaaga aactgatatc
    37201 atggacgttt ggtttgactc aggttcatca tggaatggag tggtggtaaa ccgtcctgaa
    37261 ttgacttacc cagccgacct ttacctagaa ggttctgacc aataccgtgg ttggtttaac
    37321 tcatcactta tcacatctgt tgccaaccat ggcgtagcac cttacaaaca aatcttgtca
    37381 caaggttttg cccttgatgg taaaggtgag aagatgtcta aatctcttgg aaataccatt
    37441 gctccaagcg atgttgaaaa acaattcggt gctgaaatct tgcgtctctg ggtaacaagt
    37501 gttgactcaa gcaatgacgt gcgtatctct atggatattt tgagccaagt ttctgaaact
    37561 taccgtaaga ttcgtaacac tcttcgtttc ttgattgcca atacatctga ctttaaccca
    37621 gctcaagata cagtcgctta cgatgagctt cgttcagttg ataagtacat gacgattcgc
    37681 tttaaccagc ttgtcaagat cattcgtgat gcctatgcag actttgaatt cttgacgatc
    37741 tacaaggcct tggtgaactt tatcaacgtt gacttgtcag ccttctacct tgattttgcc
    37801 aaagatgttg tttacattga aggtgccaaa tcactggaac gccgtcaaat gcagactgtc
    37861 ttctatgaca ttcttgtcaa aatcaccaaa ctcttgacac caatccttcc tcacactgcg
    37921 gaagaaattt ggtcatatct tgagtttgaa acagaagact tcgtccaatt gtcagaatta
    37981 ccagaggctc aaacttttgc taatcaagaa gaaatcttgg atacatgggc agccttcatg
    38041 gacttccgtg gacaagctca aaaagccttg gaagaagctc gtaatgcaaa agtaatcggt
    38101 aaatcacttg aagcacactt gacagtttat ccaaacgaag ttgtgaaaac tctactcgaa
    38161 gcagtaaaca gcaatgtggc tcaacttttg atcgtgtcag acttgaccat cgcagaagga
    38221 ccagctccag aagctgccct tagcttcgaa gatgtagcct tcacagttga acgcgctgca
    38281 ggtgaagtat gtgaccgttg ccgtcgtatt gacccaacaa cagcagaacg tagctaccag
    38341 gcagttatct gtgaccactg tgcaagtatc gtagaagaaa actttgcaga tgcagtcgca
    38401 gaaggatttg aagagaaata agattgaaaa gtctaggcaa aattcaattt gagaagaaaa
    38461 gacaactaat tttatagtct attaaacgca ttgtatcacg tttttgaaca cctgatatga
    38521 tgcgtttttt atttttaaaa tttgcaaggt gtgacttttt atactcatac tcaatgaaaa
    38581 tcaaaaagca aactaggaag ctagccgcag gctgctcaaa acactgtttt gaggttgtag
    38641 ataagactga cgaagtcagt aacatatata tggtaaggcg acgctgacgt ggtttgaaga
    38701 gattttcgaa gagtatcaac aagaatcaaa gagaaactta gcaagctaac agtagtaaga
    38761 taaaatagga atttgatatt agggataaga ttggtaaata gtgtaatatt tttacaacaa
    38821 taaatttata tagttatttc tggtttctga aaagtattat attatatttt atttcatatt
    38881 atacaaattt ttattttata atatcagaaa atactttttt taaaaagcaa atatgataca
    38941 attttatttg aaaaaaaata aaaaaggaga ttttattatg aaatcaagtg gtatcgtcgg
    39001 tcttgtggga ggaattttac ttcttatttg tccttttgtc ttgttgggaa cagcggtaaa
    39061 tacagctgct acaactctta atggaggagc tactgcaggg gctttttcag gtgttgcctt
    39121 actcttgaat accttgaaga ttgcaaatct tgttcttggt atcattgcta ttgtttacta
    39181 taaaggagat aagcatgtag gtgcagctcc gtctgtacta atgattgttt ctggtgaagt
    39241 tagtctcatt ccattcttag gatgagttgg ggggattctt gctattatcg gaggatctct
    39301 attccttgca acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa
    39361 gaacaaaaaa gtttatcggt ataggagtag ctctattatc tctttctctt ctagttgcat
    39421 gtggaacata aagttcaaag aatacttcaa caagtaatga tgagaagaca gtagcaacat
    39481 ccaatagttc aaaagaaaca atcactttcg atacaccggt tgtaacagac gatgcgattg
    39541 aatcaatacg cacttatgca gattatatag atctttataa aaatattttt gatgattatt
    39601 ttactaaagc tgaggaaggt ttcaaaggca cagttatgga aaataatgac tcgtttacta
    39661 aactaaaaga gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta aataatgaag
    39721 atagaataga aacagccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct
    39781 ttttggtttt gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg
    39841 gaaacctcgg aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca
    39901 cggtgagtct gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc
    39961 tgaaaaaggt acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga
    40021 atttgaccaa gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct
    40081 tgaagcttct gaccaattgt gggttccagt tgaaaaatca tggcgcttga acgaacgtca
    40141 ctacggtggt ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca
    40201 agttcacatc tggcgtcgtt catacgatgt attgcctcca aatatggacc gtgatgatga
    40261 gcactcagct cacacagacc gtcgttatgc ttcacttgac gactcagtaa tcccagatgc
    40321 tgaaaacttg aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc
    40381 agctcttaaa gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct
    40441 tgtaaaacac atcaaaggtt tgtcagatga tgagatcatg gacgtggaaa tccctaactt
    40501 cccaccattg gtattcgaat tcgacgaaaa attgaacgtt gtttctgaat actaccttgg
    40561 aaaataaaaa attgtaagcc taggattgat ttctaggctt tttatgttag tatggaagta
    40621 tgataaggaa taaaaaacaa gattatgtac tggcctacaa acaaccagct tcaaccactt
    40681 acatgggttg ggaagaagaa gctttaccga taggtaatgg ttctttagga gcaaaagtat
    40741 ttggccgtat aggggctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc
    40801 cacttcctga tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag
    40861 ctgagattcg gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc
    40921 agcacctaat tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc
    40981 acattgagtt cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagc
    41041 tgaatattag taaggcactt gtgacgactt cttatgtcta taagggaacg cgatttgaac
    41101 gtgaagcttt tgcgagtttt ccagatgatc tcttggttca gcgttttact aaggaagggg
    41161 cggaaactct agattttact atagaactat ccttgacctg tgatttggct tctgatgaaa
    41221 agtatgagca ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata
    41281 tcttgatgaa gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg
    41341 aaacggatgg agatattaga gtttggtcag atagggttca gatatcagga gccagttatg
    41401 ccaatctctt cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca
    41461 agaaactaga tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct
    41521 atacccaatt gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat
    41581 tggatttgga agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc
    41641 cacaagaagg gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta
    41701 gttcgtccag agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg
    41761 tcgacaatcc tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt
    41821 ggccagccta tgttaccaat ctcctagagg cggtctttcc ggtcatcaac tatgtagatg
    41881 atttgcgtgt ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcagaaag
    41941 gtgaggaaaa tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg
    42001 gttgggatta ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt
    42061 atgaagccta ttcattttat agggaccaag actatctcag ggagaaaatt tatcccatgt
    42121 tgagggaaac ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt
    42181 gggtgtcttc tccgtcttat tctccagaac atgggccgat ttcgattggc aatacctatg
    42241 accaatctct gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac
    42301 tggatgagga cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa
    42361 tcactcaatc tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg
    42421 agaaagtgga ggcccagcac cggcacgctt cccatctagt gggactctat cctggcaatc
    42481 tctttagcta caagggacaa gagtatattg aagcggcgcg tgctagcctc aatgatcgtg
    42541 gagatggcgg cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag
    42601 atggcaatcg agcccataaa ttattggcag agcagttaaa gacatccacc ttgccaaatc
    42661 tttggtgtag ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg
    42721 cagaaatgtt actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg
    42781 cttggtcaac aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga
    42841 gctgggaaga taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc
    42901 gagtttctta tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag
    42961 cgaaatgcat ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat
    43021 tttattttta agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta
    43081 agaatataag cagttttcaa ctagttgaaa aagcgttata atgataatag gaagtaatac
    43141 tcaatgaaaa tcaaagagca caaacaagga agctagccgc aggttgctca aaacagtgtt
    43201 ttgaggttgc agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg
    43261 tttgatagag ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc
    43321 aggttgggga cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg
    43381 agctggttat tatccttggt gcttcaggtg caggcaagtc aacagtgctt aaccttcttg
    43441 ggggaatgga taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt
    43501 atagttccca ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt
    43561 ataatctagt ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga
    43621 cagatgcctt gaatcctgat caggtcttga cagatgtagg tctggctcat cgtctaaata
    43681 actttccagc ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag
    43741 ccaaaaatcc taaaattctt ctttgtgatg aacctactgg agccttggat tatcagacgg
    43801 gcaagcaggt tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca
    43861 tcgtgactca taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg
    43921 ccagtgtcaa ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact
    43981 agtatgatca agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag
    44041 gggtgttttt tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc
    44101 aaagtaacca gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc
    44161 ttggatttgg cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa
    44221 cagacggagg gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg
    44281 caggatgcca ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag
    44341 ggacgacttc ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac
    44401 agcgtgggac aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac
    44461 catacttata ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg
    44521 ggctacgcag gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcag
    44581 tttgatcaga aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat
    44641 gtcttttcat cagcttatga agaaaaatcc aagcaacatc aggaagagct tgaacaaatt
    44701 ttatcagata atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta
    44761 gacaaggggc aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt
    44821 ttagcagctg ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa
    44881 gttcagagag agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa
    44941 gaggacaaac taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa
    45001 catcagcaag tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc
    45061 atgccaggtg gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg
    45121 ggcaatatct ttcctgtggt actttatgcc gtagcagcca tggtgacctt tacgaccatg
    45181 actcgctttg tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttatcgt
    45241 agtaaggata ttatcgccaa gtttctcctt tatggactag tagctgggac tgtcggaacg
    45301 gctctaggta gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca
    45361 aaaggcatgg tggtgggaga aacccagatt cagttctatt ggacctatag cttactagct
    45421 tttgtcttga gcttgttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt
    45481 catgacgaag cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatctta
    45541 ttggagcgta tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc
    45601 aacatctttc gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta
    45661 gctctgctct ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag
    45721 tttcaacaaa tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag
    45781 gacaaggtag agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc
    45841 tattctaaag cgctatacaa ggatttcaaa ggcaaagctg gtcttcaaaa cattactctt
    45901 atgatgatag agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag
    45961 ctgacattaa aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag
    46021 gttgggcaga ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac
    46081 tacgttggtc actttattta tatgagtcag gctagctatg agcaacttta cggacagcta
    46141 ccccaagcca acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt
    46201 caggcgggct tgcttatgaa tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc
    46261 attcgactct tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc
    46321 gtatcggttc tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag
    46381 agaatccgtg aactctccac tatcaaggtt cttggttttc ataataatga agtcaccctc
    46441 tacatttacc gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg tctgatagct
    46501 ggtttctatt tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat
    46561 ccgcaggtag gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc
    46621 ttgcttggtt tcttcgtcaa ttattatctg agaaaggttg atatgttaga agccctgaaa
    46681 tctgtagagt aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa
    46741 tcctccgttt caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta
    46801 gcagctgcaa ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg
    46861 tagcgaatcg tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg
    46921 ttgatcaaga gggcataatc gtgcccgaaa gaatggtcaa agtagtctga aagcataatg
    46981 gcattgtcaa ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa
    47041 acagtcaata cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga
    47101 gttgagcaga tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca
    47161 aaatcagcca gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg
    47221 tcgccgactt gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata
    47281 ggatactcca atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt
    47341 gaccggaaat gtgggcatag aaaaaacgcc agctcatatg agaatgacgt ttttcagagg
    47401 cttattttgc caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc
    47461 tgtcgccttc tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga
    47521 tgtttgtgtc ttgagaaacg gttttcattg gacggtcatc cacacttgat tctacaaaga
    47581 gtgatggaac ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc
    47641 cttcttcttc agtattgatt tcccagatgt aggcacttgg aacaccatag gctttagaga
    47701 agtatttgaa tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa
    47761 atttatcctt actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt
    47821 tttcatagaa ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag
    47881 caaaaataat accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat
    47941 tttgaccttc aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt
    48001 cagttttctt ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt
    48061 tgataccgtt atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg
    48121 gttcgtattc gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac
    48181 cagcaatatt tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt
    48241 gaccagaagt tgttgctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa
    48301 agagaacgag taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc
    48361 ccttatttta acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag
    48421 aagctaatga gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta
    48481 aaactatagc caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg
    48541 aaaatcatgc ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc
    48601 atggctacaa tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg
    48661 agtaccatga gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt
    48721 tcatcaaagg aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct
    48781 gcccccacac ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa
    48841 aggatatgga aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct
    48901 aagaaagaag aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg
    48961 atgtaggtaa tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca
    49021 aggcccaaga tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc
    49081 atgagtgaca tcccgcgtag aataatgaaa catcccacgg ctccagctac aatcccgacg
    49141 acaatagctg ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat
    49201 tctgcaatca taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat
    49261 tggtttcggt aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta
    49321 agacttgatc gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct
    49381 tcccagcttt tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa
    49441 tcccagcaaa gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa
    49501 tcaagacccg ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag
    49561 ctaggccgac gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc
    49621 gaaagagagg aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa
    49681 agttgtagtc gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa
    49741 cttccttgtc atcgagaaat gcctgacctt gatgtgggat aattcccagc atacctttta
    49801 atagtgttga tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga
    49861 gcactagtga aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga
    49921 tacgtatcat aaacttgtat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt
    49981 caagttaatt tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa agataacttt
    50041 caggataaat ttctaaatta taaaacgcat agtatcaagt gtaaaaaact tggaattatg
    50101 cgttttatca tggaaagatt ttttataata gctaaaaaat aatagttaaa tggttattaa
    50161 ttgcattccc tagtgatttt tgttaagata aatgcaaata caaatgaaag cgagaacaag
    50221 atgacacgtt atcaagatga tttttatgat gctatcaatg gagaatggca acagacagct
    50281 gaaatcccag cagataagtc tcaaactgga ggttttgttg atttagacca ggaaattgaa
    50341 gacctgatgc tggcgacaac agacaagtgg ttagcaggtg aagaagtgcc tgaggatgct
    50401 atcttggaaa actttgtcaa ataccaccgc ctagttcgtg attttgacaa gagagaagct
    50461 gacggtatca cacctgtctt accactcctt aaagaattcc aagaattgga aacttttgcg
    50521 gattttacag ctaaactagc agagtttgag cttgcaggaa aaccaaactt ccttcctttt
    50581 ggtgtatcgc cagactttat ggatgctaga atcaatgttc tatgggctag cgctccaagc
    50641 acaatcttgc cagatacgac ctactatgca gaagaacatc ctcagcgcga agagctcttg
    50701 actctttgga aagaaagcag cgcaaatctc ctcaaggctt atgatttctc tgatgaagaa
    50761 attgaagact tgctagaaaa aagacttgaa ttggaccgcc gagttgcgac agtggtgctc
    50821 tctaatgaag aaagttcaga atatgctaaa ctctatcatc catattctta cgaagatttc
    50881 aagaaattcg cgcctgccct acctttggat gacttcttca aagcagttat tgggcaatta
    50941 ccagacaagg ttattgtaga cgaggaacgt ttctggcaag cagcagagca attctacagt
    51001 gaggaagcct ggtctctcct taaagcaacc ttgattttga gtgttgtcaa tctttcaacc
    51061 agctatttaa cagaggatat ccgtgttttg tctggtgcct acagccgtgc cctttctgga
    51121 gttccagagg caaaagataa ggtcaaagca gcttatcatc tagcacagga acctttcaag
    51181 caagccctgg ggctttggta cgcccgtgag aagttctctc cagaagccaa ggcggatgtg
    51241 gagaaaaaag tggcaaccat gattgatgtc tataaggagc gtctgcttaa gaatgactgg
    51301 ctcactccag aaacctgtaa acaggctatc gtgaagctca atgtgatcaa accttatatt
    51361 ggctatccag aagaattgcc tgcacgttac aaggataagg tagtgaatga aactgccagt
    51421 ctttttgaga atgctctagc ctttgcgcgt gtggaaatca agcacagttg gagtaagtgg
    51481 aaccagcctg tagactataa ggaatggggc atgcctgctc atatggtcaa tgcctactac
    51541 aatcctcaga agaacctgat tgtctttcca gcggccattt tacaggcgcc tttctatgac
    51601 ttgcatcagt catcttctgc taactacggt ggtattgggg cagtgattgc ccatgaaatt
    51661 tcccacgcct ttgatactaa cggggcttcc tttgacgaaa atggtagcct caaggattgg
    51721 tggacagaga gcgactatgc tgccttcaag gagaaaacac aaaaagtcat tgaccaattt
    51781 gatggacagg attcttatgg agcaaccatt aacggtaaat tgactgtatc agaaaacgtg
    51841 gctgacttgg gaggaatcgc agcagcgctt gaagcagcta agagagaagc agacttctca
    51901 gcagaagagt tcttctacaa cttcggtcgc atctggcgca tgaaaggtcg tccagaattt
    51961 atgaaacttt tggctagcgt cgatgtgcac gcaccagcca aactccgtgt caatgtgcaa
    52021 gtaccaaact tcgacgattt ctttacaacc tatgatgtca aagaaggaga cggaatgtgg
    52081 cgttcaccag aggagcgcgt gattatttgg taatacaaaa aatctagtca tcagaaaaaa
    52141 ggcatccaat cacgtgtgaa aaccttgata ggatgccttt tgtaatagaa agatttgctg
    52201 gatagtttac ttaaatttcg attgtcatca tcttgctaga aaaagggatt gaaggccttt
    52261 tcgtgagcga tagtagtagc tggaccatgt cctggataga catcgtagtt tggtagggtg
    52321 aagagttggg tctggatact atgaaggagt tgctccatgc taccagtcgg aaggtcggtc
    52381 cgtccgatag tttcgcggaa tagagcatct cccgtcaaga ctaggtgagc atcaggaaag
    52441 actagggaaa caccaccgat agagtgccct ggggtcggta gaaccttaaa acgaaattcc
    52501 tctagttggt attcttcgtg aaagacaaag gtgtgttctg caggttttgt gaccacatct
    52561 gccatatcat cgtggcgagg gagaccggag agattatcga caggagtgta gagccagctg
    52621 gcttcgctct ctgcgatata gacaggagga ttgccaaacg tctcgcgaac caagtccaga
    52681 ctcatgatat ggtcataatg ggcgtgggtc aagagaatag cacagatcgg tttgttgatc
    52741 ttctcgattg tctgacgaat ggcttcccaa tgactaccag gatcgacgac gatgaggtgc
    52801 ttttcgcctt ctagataata ggtattttca taggcaacag gattcacggt tttatggatt
    52861 ttcatactag ctccaatctc aaagaatgta ctaatactct tcgaaaatct cttcaaaccg
    52921 cgtcaacttt atctgcaacc tcaaagcagt gctttgaaca gcctgcggct agctttctag
    52981 tttgctcttt gattttcatt gagtataaat taagtatagc acagttaggg agaataggta
    53041 aggatttaaa atgaacttaa aaaccagcat gactagatga agacaggctg gttatcaatt
    53101 tatcaatatt ggaaaggtgt caattgccct tcataggttg cataaactcc gtcattagct
    53161 tgtttgatag acgtgatgtt tagagtgcta ccgtagttgg cttctcattt gtcgctatat
    53221 tcactataag ttatcctact gggcaggttc tggtcgttag catagtattg aacgactgtt
    53281 ttttatagtt ttgctggctg aataggaaca ggcagcaaac tcctaacatt aggagagcaa
    53341 agatagaaat agcagttttt ttcataggta ttctccttat aaactaaagg atagaagaaa
    53401 gtatcttgag gatttttata ctcttcaaaa atctcttcaa accgcgtcaa cgtcgccttg
    53461 ccgtatatat gtgactgact ttgtcagtct tatctacaac ctcaaagcag tgctttgaac
    53521 agcctgcggc tagtttccta gtttgctctt ggattttcat tgagtattaa ttccaaaatc
    53581 cagtcaaggt accagtgtat gtgatacgag ttccaccgtt tatctttcgt atcttcaatg
    53641 gaattgggga aatcagaaag tatttgggtt acaatatggt ttccgttctt ctatctctcc
    53701 ttctatcacc taagtttaaa atctaacttc gtagtatatt atgggccaat aattcagaat
    53761 tatcaagcaa ttttgaatta tttttttctt attctgttcc aatctagttt tcatattctt
    53821 aaaaaagtga taaaatggta ggaagaattg gagagtagag atgccgaaag aagtgaattt
    53881 aacaggcgaa gaagttgtcg ctttaaccaa agaatattta acggaagagg atgttcattt
    53941 tgtccataag gccttggtct atgctgttga atgccacagt ggtcaatatc gcaaatcagg
    54001 cgagccttat atcattcacc ctatccaagt ggcaggtatt ttagctaagc taaagctgga
    54061 tgctgtaaca gtagcttgtg gattcttgca tgatgtggtg gaagatacag atgcgacctt
    54121 ggacgatttg gaaagagagt ttggtcctga tgtgcgggtg attgttgacg gagttaccaa
    54181 gcttggcaag gtcgagtaca aatcgatcga ggagcaatta gcggaaaatc atcgcaagat
    54241 gctcatggcc atgtctgagg acatccgcgt tattttggtc aaactgtctg accgcttgca
    54301 caatatgcgg accctgaaac atcttcgaaa agacaagcag gagcgtattt ccaaagaaac
    54361 catggaaatc tatgccccac ttgcccatcg tttggggatt tccagtgtca aatgggaatt
    54421 agaagacttg tctttccgtt atctcaatcc aacggagttt tacaagatta cccatatgat
    54481 gaaggaaaag cgcagggagc gtgaggcctt ggtggatgag gtagtcacaa aattagagga
    54541 gtatacgaca gaacgtcact tgaaagggaa gatttatggt cgtcccaagc atatttactc
    54601 aattttccgc aaaatgcagg acaagagaaa acggtttgag gaaatctatg atctgattgc
    54661 tattcgttgt attttagata cccaaagtga tgtttatgcc atgcttggtt acgtgcatga
    54721 attttggaaa ccgatgccag gtcgcttcaa agactatatt gccaaccgca aggccaatgg
    54781 ttatcagtct atccatacga ctgtttatgg accaaaaggg ccgattgaat tccagattcg
    54841 aaccaaggaa atgcacgagg tggctgagta cggggttgcg gctcactggg cttataagaa
    54901 aggtataaag gggcaagtta acagcaagga atcagctatt ggaatgaact ggatcaagga
    54961 gatgatggag ctccaagacc aggctgatga tgctaaggaa tttgtggact ctgttaagga
    55021 aaactatttg gctgaggaga tttacgtttt taccccagat ggagctgtcc gttcccttcc
    55081 caaagattca ggaccgattg attttgccta cgaaatccat accaaggtcg gtgaaaaagc
    55141 aactggtgcc aaggtcaatg gccgcatggt tccactgaca accaagttaa agacagggga
    55201 tcaggttgaa attatcgcca acccgaactc ctttggacct agccgtgact ggctcaatat
    55261 ggtcaagact agcaaggcgc gcaataagat tcgccagttc tttaaaaacc aagataagga
    55321 attgtctgtc aacaagggtc gtgagatgct gatggctcag ttccaagaaa atggctatgt
    55381 ggcaaataaa tttatggaca agcgccacat ggatcaagtt ctgcaaaaga ccagttacaa
    55441 gacagaagac tccctctttg cggccattgg ttttggggaa atcggtgcga ttaccgtctt
    55501 taaccgtctg actgaaaagg agcgccgtga ggaagagcgt gccaaggcca aggctgaggc
    55561 agaggagctt gtcaaaggtg gcgaggtcaa ggttgaaaat aaagaaactc tcaaggtcaa
    55621 gcatgagggg ggagtggtta ttgaaggtgc ttctggtctc ctagtgcgga ttgctaagtg
    55681 ttgtaacccc gtgcctggtg acgatattgt tggctacatt accaagggtc gtggtgtggc
    55741 tattcaccgt gtggactgta tgaacctgcg tgcccaagaa aactacgagc aacgtctcct
    55801 tgatgtggaa tgggaagacc agtactctag ctcaaataag gagtatatgg cccatatcga
    55861 tatctacggt ctcaaccgta caggactgtt gaacgatgta ctgcaagttc tttcaaatac
    55921 aaccaagaat atttcaacgg tcaatgccca accaaccaag gatatgaagt ttgctaatat
    55981 ccatgtgtcc ttcggtattg ccaacctctc tacactgact acggttgtcg ataaaattaa
    56041 gagtgtgcca gaagtttact ctgtcaaacg gaccaacggc tagttgtcct agctcttact
    56101 agaaaggcta ttatgaaaat cattatccaa cgggttaaaa aagcccaagt gagtatagaa
    56161 ggccagattc agggaaaaat caatcaggga cttttattgc tggttggtgt tggaccagag
    56221 gaccaagagg aagatttgga ctatgctgtg agaaaactgg tcaatatgcg aattttttca
    56281 gacgcagaag gcaagatgaa cctatctgtc aaagatattg aaggagaaat cctctctatt
    56341 tctcagttta ccctctttgc ggatactaag aaaggcaatc gtccagcctt tacaggggta
    56401 gctaaacctg atatggcatc agacttctat gatgctttca atcaaaaatt agcgcaagaa
    56461 gtgcccgttc agacaggtat ctttggagca aatatgcagg ttgagctggt taataacgga
    56521 cctgttacca ttatcctaga tactaaaaag agataagaaa gaccaagccc agtcggcttg
    56581 gtctttctca tctatcataa aatactccaa aaagaaatcg gttcttgata tgcttggggg
    56641 aagtctcttt tcaggctttg gcagatgcga taggaaggga tgagatgtcc taggatgagg
    56701 agagttccct gaaggaaaag tggaatatca cttaaagaca ccaaggagag aatcatcagg
    56761 ctatcccata ggagaatttg taaagcaaaa cgccagaatc tcggtctaat ctgggaatag
    56821 agttgactaa agtggtcaca aagttggttt gaaagatagg tcaatagcac aggatgaaag
    56881 aaaatgagcc aaccgctata aatcaaaatc cagtcccaag taagcccccc tttttaaatg
    56941 tcaaaaatgc cagcatgatt ccatcaatga caaggagttg aatggttttg atgaagatga
    57001 tttttttcat gctaaaacct ccttttcctt agagacactc ccctacaggt attttagaat
    57061 gtatattgct tagatattcc ttattttatt agctttttaa ggtattaaag tagttatata
    57121 agtttatgaa gggtatccta tcctgcacgg ctaattttga gttcgaaact gaggagttta
    57181 taactcaaaa tttcgattaa atcagcattt aacgatagta tgtttgtcat aaaatgataa
    57241 atttttagat tgtggaaatt ttttttaact taattcttga ttttttttct aaatgtgata
    57301 tacttaattt acgggataaa aaaaccacct tagaaaggtg tgataatgtg caaaaagaga
    57361 atgttagaat gcgtttagcg tctgaatcca gacagatatt agataagctt aaagatgatg
    57421 tttacaataa attaggctat gaagtaagct attccagtat tgttagtcaa gctgttagag
    57481 aatacgttcc taaaaaagaa cgtatagatt ggataaaatt aaaagagaca gctataccct
    57541 tttcatcgtt aaaacagagc aataattggg agtaccagac atcacttatg ttagaggaag
    57601 atgtattaat cttactgtct gaactacaaa attttttctt agatgtcttc caagcgaaac
    57661 gtatacatag ggcattttgt gtacgcctat gcttgaaagc acaattttta ttaagtaata
    57721 atgattctta atactatcaa tattaatgcg gagtgtaatg ctccgctaaa ataaaaccta
    57781 ttacgggata aaaacactac tttatttagg atggaaagag gaacgaatga agatgaaagc
    57841 tagagattca ccattgaatt gattttgttt ttagaaaaaa tcaataatta gaaaaaatac
    57901 gaggtaaaaa aatgaataga gatgtattag agtttctgag aacagagacc gctgaaaaaa
    57961 ttagtcttta tataagcgag gctaatagat tggagggcga tgtaactcta ctcgcaccta
    58021 gttctcaaga tttggaagat attaaaaatg ctatgctttc caattctaat ctcggattaa
    58081 aagttgcgag actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt
    58141 taacaggggc tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa
    58201 gttatgtcta atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa
    58261 gtataaaaat gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga
    58321 agaaatcgat aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt
    58381 ttctcctagg tagtcagctg tcatataata aaaagtagaa tggcaagcag tgataattgg
    58441 cataagagat gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc
    58501 aatggtgaga acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc
    58561 agcgaattga tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa
    58621 gaaaattaaa ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa
    58681 tgcaaatagt agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt
    58741 catgacaaga ccttcctctt ttatctaact tcattctact ccaaaagaat gggagttaca
    58801 actaaaatga taaaaatagc agaagggaga ttctcttaag ttggctagta ttctttattt
    58861 gagtttcctt ctatgtatct aacttcttca tcattccaga caaataaagc tccgattgca
    58921 ttgaggatat aaaagatgta tttaccgata ttggcgaagt ttccttgaat accagctttt
    58981 gtcagctgaa cgaaattgta aatcaaccaa aagccccact gagttgttag tttcaatgca
    59041 ttcaaagcat tggcaatgag ggacagtgca aaggcaatag ttgttacgta ggcaaggaga
    59101 ttcatcttgc cctcatatcc gatatagttg gtcacaaagg caaagaggaa ggcgatgatg
    59161 gaaatgatga tggccgccaa ttttacctgt ttttggctca tttggttggg tctgccttct
    59221 tgcgaagctt tccatttctt tatagcaaag gtataaatga ggaaggtgac gggataggta
    59281 atgatggccg ccttatttcc aaggatataa tcaatagcac cggacaaaat ggtattaaca
    59341 ataccaaagt aatttcccca tttgcttaat ttccccgtga aacgagtgga caacatggaa
    59401 atcccaacgt tggttacgga aatcaatcca aagggtacaa gagctgtcca tggtccccag
    59461 tctacaaatt tatcgaggcg tgagttgagg taaccagatg caatcgcaat ccaacgacca
    59521 aagcaacccc gaagaggtca aactatttag atgtagcaaa aatttttagt gattttttca
    59581 taggttaaac tacctttctt tttttcaaat attctcccac caaatgaaag taaaataaaa
    59641 tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact tgagaaatta
    59701 gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta aatcctcgtc
    59761 gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttgactt ggagctggtc
    59821 accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat cgtgcacccg
    59881 agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat tgatttcaac
    59941 gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag ggaaacctag
    60001 cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga cctcagcttc
    60061 ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt caatcaagcg
    60121 gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta gatagccaca
    60181 ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt cagttacggc
    60241 agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat gcaggtctat
    60301 gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc gtttcctctt
    60361 gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg tgacttttta
    60421 tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat agctcttctt
    60481 tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc tcagcagcta
    60541 ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg acgtagaagg
    60601 attttggact tgttggatca actaccgatt acggctagag ttttgggaaa ctgggaagac
    60661 agtctttggc atggtgtccg taaggaattg gatagtactc gccctagtca acgctatctc
    60721 ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga agtgctccac
    60781 aatcaacctc ttcaaattca tcgtcagttt ggggatttga cagtgggaat tagccatcat
    60841 ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga gaattttgac
    60901 cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacatattca ccagcagttg
    60961 cttcgtcacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg ccaacctttc
    61021 tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt ggagtttgat
    61081 ggcaagggcc tggtagatat ggacttccga cgggtagact acgatgtggc agctgaattg
    61141 cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag tctggtcaat
    61201 gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa agagggttgc
    61261 gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa ctaaaaaggg
    61321 tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga gaagaggatg
    61381 caaattccaa gtagatttac cattgcgact catatgctga taatcattgc cctcgagggg
    61441 aaggaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa tcctgtcatt
    61501 atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc gcgtggaacg
    61561 ggcggaacag agattgtcaa ggaccttaag gatattagtc ttttagatgt ttatcaggcg
    61621 gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc gaatccaaat
    61681 tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag aattcagttg
    61741 actatggagg cagaacttgg tcagaccagt ctagaaaaag tcgtggccga tgcagagagt
    61801 cagatgaagg attaagaggg ataaatgccc tctttttttc tttggataat tatgataaaa
    61861 tgtagctatt aaaggagtaa gaaatgtatc tcgttataga aattgtatta gcctttatag
    61921 tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta ttatccctca
    61981 tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag aatgttcagt
    62041 tagcttttta tgtatttacc tttgtcttac ttcctttttt gctttttcta agtggcatct
    62101 ttttaatcta taatggggtc attttgttga aacgagaggg acgttccaag ccccattatc
    62161 tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac ttagaatgca
    62221 catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca agagtattat
    62281 ctatttttcc atgcatggta acgagtatca atcaataact gggtaaggcg acccaaggtt
    62341 tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat gtattcaagc
    62401 gcctttaagg aagccaagtc attgatagag ctaataccag catcaagaat agtgccaaag
    62461 aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca ttctttaaag
    62521 gttgtgtcta cttgccggct atcactgttg gtcttatcca gttgaacgaa gtgcttgtcc
    62581 tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt actctgaacg
    62641 atgatttggt gagcaggaat ttccagcatc ataccgataa tagacccttg tggaatgaat
    62701 atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc ttgatggaga
    62761 ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg ctcaatttgg
    62821 ctagcagcat agatagcgag atttcctccc ttggaatgcc cagccagaat aaccttttgc
    62881 ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg agcaggaatt
    62941 tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc atctgtccca
    63001 cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc aaattgcttt
    63061 tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt gaagcgcttg
    63121 tgttgagcca attcatctaa taattgaagg cgatttttgc tagtaagcat ggtgggctct
    63181 cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac cagattatca
    63241 aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa gggaaggtcg
    63301 taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat aagagctcct
    63361 ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag cctgtttgta
    63421 ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg aaaaatctgt
    63481 tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag atgatcaggt
    63541 cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg tcctggtaga
    63601 agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg tcctcatgga
    63661 tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca agatttccaa
    63721 ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca tggcaatcaa
    63781 tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt tagctaaggt
    63841 tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc tggaatatgc
    63901 tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag tcttgaattt
    63961 gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca acatcgtagc
    64021 acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg ataataccct
    64081 ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg taggatttat
    64141 cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa caattttttc
    64201 tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttttttg gcatttcttg
    64261 tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac tttttcttct
    64321 tgtgttgctt tgtaaccatc ttatttttca cttgggacat attggtggaa acgcaggtct
    64381 atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa atagctttag
    64441 cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa gcagaaagaa
    64501 aactgacgga tttgctggat tactatacct tgtgggttca tcagataaag acccccattg
    64561 cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag cagctagaac
    64621 aggaaatttt caaaatcgac tcctatacca acctagtttt acagtacctg cgtttagaaa
    64681 gtttccatga tgatttggtc ttaaagcagg ttcaaattga ggacttggtc aaggaaataa
    64741 ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta catgaccttg
    64801 ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa atcatctcaa
    64861 acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac caagagcttt
    64921 gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta tttgaacgtg
    64981 gcttttcagg atacaatggc cgtttgaccc agcagtcctc tggacttggc ctttatctat
    65041 ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag gtcggaaaag
    65101 gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa aaatagatga
    65161 gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac gcgtgatttg
    65221 ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt ttgtgtttct
    65281 ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc tccaacaatt
    65341 aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat tttttcattg
    65401 cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggccac ttcccaagcg
    65461 tagttcacgt gtttttcgtt agatactggg atgagggtta cttggtgtgg tgccagccat
    65521 gttgggaagg cccccttgta gttctcaatc aagatagctg tgaagcgttc catagttgag
    65581 ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc gatgtatttg
    65641 aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt ttcttctttt
    65701 ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggctgc ttcaccttcg
    65761 gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt ttgggcattt
    65821 tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg aagagagagg
    65881 cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa ctgaagggca
    65941 cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc gttgagtgac
    66001 atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg gtgcatcata
    66061 ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg tttgaaaact
    66121 tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc acccatgtcc
    66181 atggttggga acatgtcttc ttggtaatga tcccagtgac cagaagtctt gtaaagctca
    66241 acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc tttgtttacg
    66301 atgtagcgtt ccaattcacg acggatagtc gcaccatttg gcaaccagaa tggcaaacct
    66361 tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt acggtggtca
    66421 cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt gtcaaaccaa
    66481 gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca gtaagcacca
    66541 gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacgtg aggtccacgg
    66601 cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc ttctgagtgt
    66661 tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc ctcgtcttta
    66721 gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat ttcttcttcg
    66781 atacgaggaa ggtcttcgtt agagatttga ccagctatgt tgtcagtatc gtagtagaaa
    66841 ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg acgagctgct
    66901 tgggcgaaca agtgagctgc tgagtgacgc aagattggaa gggcatcttc gtgatcaggt
    66961 gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat gagtttgccg
    67021 ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg ggcaatttca
    67081 aaagttgtta cgccagattc gaattcacga acagcgccat ctgggaaagt aatgttaatc
    67141 atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt atcagcagac
    67201 tacttccaag tcctaacgtt caattgcttt tctttatcag agaggaagtt ttccatttcc
    67261 gtcagaatgt ctatatccaa acgttgagaa agttctaata gccaccagat attttctgaa
    67321 agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt tgtcatcacc
    67381 aatcgttgga aatttccaat atcattagat aaagccaaga ggtcttcttc taccgtccac
    67441 ttggaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc ccaactgtgc
    67501 tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga catcctcgaa
    67561 aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg gacacctctg
    67621 atcggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag tagtatcagt
    67681 ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg actaagtgac
    67741 ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt gtgaaagttt
    67801 tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca tgcccaccag
    67861 agcaactgtt tcatagatta gcaagtaaat tagtataaac tcaccaaaga ttatgatagt
    67921 gaagtaaaag agcagtccgt taccaactaa ccatcaaagt gagaaacgga aacggtagct
    67981 atagagtaac gatacaatca agattaccag aggtgtaaag aagagaagat tgtttatata
    68041 gagtcccttg agtgtaaggg ggtcagaaac aactagcaag aacaactcat aaagtggcca
    68101 ataaatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat aatcacctcg
    68161 ttttaaaaaa aacagacaac ttagatctct tgctatgatt attataagca tgtttaaaac
    68221 aagaaagtaa atttgttgac aaagaagatt tttcttttca ctagaatcat agttagtttt
    68281 cttggtagaa atattttgat aataattaag caagactatt gacattgatt attaagagtg
    68341 tcacaattgc tgtaactaaa ataattacaa caagagaggt ataaaaaatg aaactagcag
    68401 ttattgcagc aaatggacaa gtggggaaag caattgttga agaagcagtc aaacgaggac
    68461 atgaagtaac ggctattgtt cgttctgaaa acaaaagtca agctgagtct attattaaaa
    68521 aagatttatt tgagttgaca aaagatgatc ttactggatt tgatgctgtt atttcagcgt
    68581 ttggtgctta tacaccagat acgctaccgc tccatagcaa atcaatcgaa ctatttaatc
    68641 agcttcttgc tggaacacag acacgttttc tagttgtagg gggagcagaa agtctttata
    68701 tagatgaaac aaaaacgaca cgacttttag atacgtctga ttttcctgaa gaatttaagt
    68761 cactagcaaa agctcaagcg gatgaattgg atcttcttcg tacaaaaaat aatctcaact
    68821 ggacttttgt cagtcctgct gtagatttta ttcccgatgg tgaaaaaaca ggaaactaca
    68881 ttctagcagg agaaattttt actactaatg aaaaaaggaa taagccagat tagttatgca
    68941 gattatgcta ttggattggt agatgaactt gaaaaaggtc atcatataaa agaacgtatc
    69001 tctttacttg aaaaataata actatgagag tattaatgtt tgacagaaaa tttaaatctt
    69061 ggtaaaatag ggattgtcgt aaagacaaat aacttcttct tggttacagg catgccaacc
    69121 tgtcactcgg atgaagccaa ataaaaagga gaaacatcat ggcaatctca aaagagaaaa
    69181 aaaatgaaat cattgcacaa tatgcacgtc acgaaggtga tacaggttca gtagaggttc
    69241 aagttgctgt ccttacttgg gaaatcaacc accttaacga acacatcaaa caacacaaaa
    69301 aagaccacgc tacttaccgt ggattgatga aaaaaatcgg tcgtcgtcgt aacttgcttg
    69361 catacttgcg taaaaacgac gttaaccgtt accgtgagtt gatcaactct ctaggacttc
    69421 gtcgctaatt caagatacaa aggccgtcaa aagcacaaag caaaaatagg aaaattgacg
    69481 aagaaacttc agtttctagg agattttatc ttttttgcca agtgcttagg ccgtgttcaa
    69541 ttgagcatat cttgataata aagctactct aaattgggta gcttttttgc gttgtcacct
    69601 tacctcgcta tactcaagta taatctttgg ttacggttcc tagcactgta aggtaaaata
    69661 aaccagcttt tctcccttcg gggagatttt ttttgtttca ctgaaagttt cgtacgatct
    69721 tcgcctcgtc gcctagtcta taaacgattt atctagcaag aatcatgatg ctaagggcgt
    69781 caaaaatccg tatgaaaata gggaaatgac acagtgttcg atgagcacaa ggagtttcat
    69841 ctttttcact aggattttag cccgggctaa aatcagctct ctgacttcag agggcttttt
    69901 tattgaggtt ttatcggtaa caattttgga gactacaaaa acctcaaatg gtatcagcta
    69961 attacaccat aaaggtgcgc agttactcgg cttttcaagc cgagtagctg tatgcaagcc
    70021 ccctagaaga gcccactctt tacaaagtaa agtatagtat gttatacttt acatggaagt
    70081 agtcactgaa ttccagttag aaattacttt gtaactacgt tttgaggagg agtaaaatgc
    70141 tttcctacgt tcgacattac ccactagcga tagctaaatt aatgtgtctg tgctctcctg
    70201 aaatctgctg atttattact gactaataca ggaggttttt tttatgggac agacaatcat
    70261 atctgctatt ggtgtttata tttccaccag tatcgattat ttaattattt taattatttt
    70321 atttgcacag ctatcacaga ataaacagaa atggcatatt tatgcggggc aatatctagg
    70381 cacaggctta cttgtagggg cgagtttagt tgctgcttat gtcgttaatt tcgtgcctga
    70441 agaatggatg gttggattgc ttggtttaat ccctatctat ttagggattc gctttgcaat
    70501 tgttggagaa gatgcggaag aagaagagga agaaattatt gaaagattag aacaaagcaa
    70561 ggcaaatcaa ctgttttgga cagttacatt gctgacaatt gcgtctggcg gagataattt
    70621 aggtatctat ataccttatt ttgcttcgtt agattggtca cagaccctcg tggccttgct
    70681 tgtgtttgta atcggcataa ttatcttttg cgagattagt cgggtgttat cctctattcc
    70741 gttaatattc gagacaattg aaaaatacga gcgaatcatt gtgcccttag tattcattct
    70801 acttggacta tacatcatgt atgaaaatgg cacgatagag acttttctga tcgtgtagat
    70861 ttttttgttt cactaggatt ttagcccgag ctcaaatcag ctctctgatt ttcagagggc
    70921 tttttcattg agtataaatg gacaatctta aagttactct attgtagagt ggcttttgat
    70981 ttgattagga gattcttata aatatagtaa aatgaaacaa aaacaggaca aatcgatcag
    71041 gacagtcaaa tcgatttcta aaaatgtttt aagaagtaga ggtgtactat tctagtttca
    71101 atttgctata taaatgaaaa ccttagctgt ttggccaagg ttcatttctt ctatgcaagt
    71161 tcttctcttt tcttatctgg gttccagatg aagcttgcga taaagctaaa gatgatggtt
    71221 aggatagcga ggataatagc aaggatgagg gcagggatgc ggataaacca ccagagtgga
    71281 tttggttttt tatcattgtg ccattgtttc gtttcttcgt ccagacgttg gaattctgtt
    71341 tgaatacgat tggcgactgt ttcaatgcct tcatcattca ttttcttgat atctgagata
    71401 tcgattggat ttccaaagtt catatcgaca cgttcacggc taatcaagcc cttcaaaatc
    71461 atgggaccgg tgtaggtaac cggcatgata cggaccttgg ccattttggc aatcagtgct
    71521 gcgcccccct tgacatcgtt tgagtggcgg ctaccacttg gaaacatgat gagagagcgg
    71581 tcactttttt tgagaacgtt gataggatat ttgatggctg aggcgctggg attttcacgg
    71641 tcgatgggaa aggcgccaca catacgaatc caccaaccaa agatacggtt ggtaaagagt
    71701 tctttttttg ccataaagat gaactgtttt ggcttggtcg caaaggccat ataaacagga
    71761 tcccaccagg tacggtgagg cgcaactaaa atataatttt catcttgatt aggaatttta
    71821 tcagtattat gatagtgagc attgccattg atggaccata agagcaacac aactaatcca
    71881 cgcaaataag tataaaacat gcgatctcct tcgattgttt tcttgttatt attatacctt
    71941 atcaaaggag ggctggcaaa cttttccctt gactagatgc atatttggga tgaaattaga
    72001 attctgttaa aaaaaatggt ataatagaat ttatggataa aaataagatt atgggattaa
    72061 cccaaagaga agtcaaggaa agacaggctg agggtttggt caatgacttt accgcatcag
    72121 ccagtaccag cacttggcaa atcgttaaac gaaatgtctt tacccttttt aacgctttga
    72181 actttgccat tgctttggcc cttgcctttg tgcaggcttg gagcaatctg gtcttctttg
    72241 ctgttatctg ctttaacgct ttttctggga ttgtgaccga gctacgagcc aaacacatgg
    72301 tggacaagct caatctcatg accaaggaaa aggtcaaaac catccgtgat ggtcaggaag
    72361 ttgctcttaa tcctgaagaa ttagtgctag gagatgtcat tcgtttgtct gcaggagagc
    72421 agattcctag tgatgccttg gttttggaag gctttgcgga agtcaatgaa gccatgttaa
    72481 cgggagaaag tgatttggtg caaaaggaag ttgacggctt acttttgtca ggaagtttcc
    72541 tagccagtgg gtcagtttta tctcaagttc accatgtcgg tgcagacaac tatgctgcca
    72601 aactcatgct tgaggctaag accgttaaac ccatcaactc ccgtatcatg aaatcgctgg
    72661 acaagttggc tggttttact gggaagatta tcattccctt tggtctggct ctcttgctgg
    72721 aagccttgct tttaaaaggc ctgcctctca agtcatccgt tgtaaactcg tcgacagctc
    72781 ttttgggaat gttgcctaag ggaattgccc ttttgaccat tacttcgctc ttgactgcag
    72841 tgattaagtt gggcttgaaa aaggtcttgg tgcaggagat gtactctgtt gagaccttgg
    72901 cgcgcgtgga tatgctctgt ctggacaaga cgggcaccat cacccaagga aagatgcagg
    72961 tggaggctgt tcttccactg acggaaactt acggtgaaga ggctattgcc agcatcttga
    73021 ctagctacat ggcccatagt gaggataaga atccaactgc ccaagccatt cgccagcgtt
    73081 ttgtgggaga tgttgcttat cctatgattt ccaatcttcc cttctcgagc gaccgcaagt
    73141 ggggggctat ggagttagaa ggcttgggga cagttttctt aggggcacct gagatgttgc
    73201 tggattctga agtcccagaa gccagggagg ccttggagag aggatcacgt gtcttggtct
    73261 tagctctcag tcaggagaaa ttagaccatc acaaaccaca gaaaccatct gatattcagg
    73321 ctctagcctt gctggaaatc ttggacccca ttcgagaggg agcagcagag acgctggact
    73381 atctccgttc tcaggaggtg ggactcaaga ttatctctgg tgacaatcca gttacggtgt
    73441 ccagcattgc ccagaaggct ggttttgcgg actatcacag ctatgtagat tgctcaaaaa
    73501 tcaccgatga ggaattgatg gccatggcgg aggagacagc tattttcgga cgtgtttccc
    73561 ctcatcaaaa gaaactcatc atccaaacgt tgaaaaaagc gggtcataca acggctatga
    73621 caggggacgg ggttaatgat atcttggccc ttcgtgaggc ggattgttct atcgtgatgg
    73681 cggaggggga tccagcaacc cgtcagattg ccaatctggt tctcttgaac tcagacttta
    73741 atgatgttcc tgagattctc ttcgagggtc gtcgcgtggt caataacatt gcccacatcg
    73801 ccccgatttt cttgataaag accatctatt ccttcctgtt agcagtcatc tgtattgcca
    73861 gtgctttact aggtcggtca gagtggattt tgattttccc cttcattccg atccagatta
    73921 ccatgattga ccagtttgtg gaaggtttcc caccattcgt tctgactttt gagcgaaata
    73981 tcaaacctgt tgagccaaat ttcctcagaa aatccatgct tcgtgcccta ccaagcgctc
    74041 tcatggtcgt cttcagcgtc ctgtttgtga aaatatttgg gagtagccaa ggttggtctg
    74101 agttagaaat ctcaactcta ctctattatc tcttggggtc aattggtttc ttatccgtat
    74161 ttagagcctg catgccattt accctatggc gtgtcctctt gattgtttgg tcagtaggag
    74221 gtttcctagc cacagctctc ttcccaagaa ttcaaaaact gcttgaaatt tcaaccttaa
    74281 caggacaaac attacctgtt tatggtgtca tgatgttggt ctttaccgtg attttcatcc
    74341 tgaccagtcg ttaccaagcg aaaaaataaa gaaagactgc aatctgtgga ttgcggtttt
    74401 tttaggtaca agattgccag ccgaaatgtg gtataataag aggtaataga gtttggaaag
    74461 tgagagaaaa tgatttcaaa gagattagaa ttggtagctt cctttgtgtc acagggggct
    74521 attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt tgagagaggc
    74581 caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc tgcggttaaa
    74641 aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa tggcttggca
    74701 gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg tggtcgtttg
    74761 attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg tttgatcctc
    74821 cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg attccagatt
    74881 gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt ggtggaagca
    74941 ggacaaatga agctatcagc cagtgatgtt cgctttggtc ccttcttgtc caaagaagtc
    75001 agtccagtat ttgtccaaaa atggcaaaaa gaagctgaga agctagagtt cgccctcgga
    75061 caaatcccag aaaaaaatct ggaagaacgt caagttctag tagataagat tcaagctatc
    75121 aaggaggtgc cccatgttag caagtgaagt gatccaagct tatgaagcct tttgccctca
    75181 ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag acaagggtat
    75241 ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg ccattgaaaa
    75301 gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca aggacttgct
    75361 tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgata tcgcagttta
    75421 tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt tttgtcagat
    75481 gctaggaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg gaattggacg
    75541 tattgggaat attcagcctc agacattttg ggaattggcc caacaggtca agcaagtctt
    75601 tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga agcctatttc
    75661 aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt tggcaaaggg
    75721 ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata tgctgtctga
    75781 tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg aaaaaatcgc
    75841 agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt tacctagtca
    75901 agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg aaaaaagttg
    75961 ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg agagaaagtg
    76021 acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc gcagcaggaa
    76081 ttatcagtcc ttggctttca aaacgccgca ataaggcctg gtacaagatg gcgcgattgg
    76141 gggctgactt ttatgtggat ttattagctg atttagagaa atcaggacaa gaaatcgact
    76201 tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaagttg gaagaactct
    76261 atcaactggc tctccagcgc agagaagaat ctcccttgat aggccagtta tccattctgg
    76321 accaagcccc agctaatgaa ttattccctg gcttgcaggg attcgacaac ttgctctatg
    76381 cttctggtgg agcgagagta gatggtcacc tcttagtaac tcgtttgctg gaagccagtc
    76441 aggtcaagtt ggtcaaagaa aaagtgactc tgacactctt atcatcaggc taccagattg
    76501 gcgaagaggt gtttgatcag gttattttgg caacgggagc ttggttgggg gacatgttag
    76561 agcctttagg ttatgaagtg gatgtccgtc ctcaaaaagg acaactacga gattatcagc
    76621 ttgcccaaga catggaagat taccctgttg tcatgccaga aggggagtgg gatttgattc
    76681 cctttgcagg tgggaaatta tccttgggcg ctacccatga aaatgacatg ggatttgatt
    76741 tgacggtaga tgaacccttg ctccaacaaa tggaggaggc ggccttgcct cattacccag
    76801 ttttagctag agtgacttca agggctgagc gtgtgggaat ccgtgcctat accagtgatt
    76861 tctctccctt ctttgggcag gtgccagaat tggcaggtgt ctatgcagcc agtggactag
    76921 gttcatcagg cctcacaact ggtcctatca ttggttacca tctagcccaa ctgatccaag
    76981 acaaggagtt gaccttggac cctgaaaact acccaattga aaactatgtc aaacgagtaa
    77041 aaagcgaata atactcaatg aaaatcaaag aacaaactag gaaactagcc gcggattact
    77101 caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg
    77161 aggttgtgga tagaactgac gaagtcagta accataccca tggcaaggcg acgttgacgt
    77221 ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc aggtagttta
    77281 ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa tctgagaatc
    77341 gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt attggaaccc
    77401 acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat aatcttgtca
    77461 atagcaatcg taagagttta gaagttgttg aaagaatcac aggagttgag attcctttct
    77521 atgaggcaga tattcgtgac acagataccc tcagagatat tttcaagcag gaagaaccga
    77581 ctggtatcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt atccctcttg
    77641 cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg gaagaaaaca
    77701 actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg cacacagtgc
    77761 ccatcttgga agatttccca ctttcagtga ccaacccata cggtcgtact aagctcatgc
    77821 tagaggaaat tttgactgat atttacaaag cagactcaga atggaatgtt gtcttgcttc
    77881 gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat ccaaacggta
    77941 ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta gagcaagtgc
    78001 aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgat tatatccacg
    78061 ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa ggttcaggac
    78121 taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt atccaaaaca
    78181 tggaaaaagc ggtgggacgt cctattcctt accgcatcgt agaacgtcgc ccaggtgata
    78241 tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg gaagcagaac
    78301 tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat ccaaatggat
    78361 ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga ggaagtactt
    78421 cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga aatcgagtat
    78481 gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc ctatcgggag
    78541 caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga agcagccctt
    78601 tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc agacctccaa
    78661 gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt agacttggac
    78721 tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag tttctgtgct
    78781 gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc gggtgtccgt
    78841 gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac cgagtccaat
    78901 cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt ggactatcca
    78961 aatgtcgaaa ggcaggctgg caagacaagt tggagtttta ggcaactctt tttctactcc
    79021 attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt agctggtctc
    79081 ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac cctcattttg
    79141 ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct tggaggcatt
    79201 caactcttga ccattgggat tctcggcaag tatatcagta agatttattt agagactaaa
    79261 aaaagaccac tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat
    79321 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    79381 ccattgattt aggcttcctg gtttccaatc agggcgcgcg ttgggcaatt tttaacagcc
    79441 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    79501 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag
    79561 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    79621 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg
    79681 atcaagaaga atcaagagca gagcgtcggc atcgaaacca cggaggggct gataggatgg
    79741 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    79801 tcgttctcat ctatctatca tcggggggaa gtaatcgcac agcagcctta aaagactttc
    79861 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    79921 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    79981 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    80041 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    80101 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    80161 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    80221 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    80281 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    80341 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    80401 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    80461 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg
    80521 cgatattgga actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt
    80581 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagacct
    80641 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    80701 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    80761 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    80821 gattgatatc ggttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    80881 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa tcatgaacaa
    80941 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    81001 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    81061 tgtcgctatc gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa
    81121 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    81181 ccacatcgta gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    81241 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    81301 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag
    81361 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    81421 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aagaccaagt
    81481 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    81541 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    81601 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    81661 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    81721 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    81781 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    81841 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    81901 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    81961 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    82021 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    82081 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    82141 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    82201 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    82261 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    82321 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    82381 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggagcac
    82441 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    82501 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    82561 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    82621 tctttctagc ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt
    82681 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    82741 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    82801 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    82861 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    82921 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    82981 tggggcaaat tgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    83041 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    83101 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    83161 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    83221 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    83281 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    83341 gcaaactata gttgattgag tttggaatag tacgctgtag ctgctaaaat atttctagaa
    83401 attaatttga ctttcctaat agagttattc atatcttatt tcaatctact atagaaagct
    83461 agccgcaggt tgctcaaaat agtgttttga ggttgcagat ggaaactgac gtggtttgaa
    83521 gagattttcg aagagtatga gatttttata cccatacaat atttgtttta ggtccttgtt
    83581 tacagactaa tttcttgata aaatagaggt tatgacgaga tataaagcaa ctatttccta
    83641 tgatggttat gcctttgctg gctttcagcg ccagtctcat gcgcgtagcg ttcaggaaga
    83701 aattgaaaaa accttgacca gattaaataa agggcaagcc attactgttc acggtgctgg
    83761 taggacagat agtggggttc atgccctggg acaggtcatt cattttgacc tgccttatca
    83821 gattgatgag gagaaactcc gttttgcctt ggatacccag tctcctgaag atattgatgt
    83881 gatttcgatt gagcttgtgg cagatgattt tcattgccgt tatgccaagc atagcaagac
    83941 ctatgagttt attgtggata gaggacgtcc caaaaatccg atgcgccgtt actatgccac
    84001 ccactttccc tacccactcg atgtggaacg aatgcagatt gcaatcaaaa agctagaggg
    84061 aacccatgat tttaccggtt ttacagcctc tgggactagt gtagaggata aggttcgcac
    84121 catcacagaa gctagtttaa tagtcgatga gacaggacaa tttttgacct ttaccttttc
    84181 cggaaatggt ttcttgtata aacagattcg caatatggtg gggactcttc tcaaaatcgg
    84241 taacaaccgc atgccagtag agcagattga tctcatcttg gagaagaagg acaggcaact
    84301 tgcaggtccc actgcagcac caaatggttt gtatttaaag gagattcgtt atgaagaata
    84361 atcgtatttt agcactttct ggaaatgata tttttagtgg tggtggactg tcagctgatt
    84421 tggctaccta taccttgaac ggcttgcatg ggtttgtagc agtgacttgt ttgacagcct
    84481 tgacagaaaa aggatttgaa gtctttccaa ctgatgatac catttttcaa catgaattag
    84541 atagcttgcg tgatgtggaa tttgggggaa ttaagattgg tcttctccct actgtcagtg
    84601 tggctgagaa ggccttggac tttatcaaac aacgcccagg agtacctgtg gtgttggatc
    84661 ctgtcttggt ctgcaaggaa acgcatgatg tagctgtcag tgagctctgc caagagttga
    84721 ttcgcttttt cccttatgtc agtgtgatta cgcctaatct cccagaagca gaattattat
    84781 ccggtcagga aattaaaacc ttggaagaca tgaaaactgc agcgcagaaa ttgcatgatt
    84841 taggagcgcc agcagtcatt atcaagggag gcaatcgtct tagtcaggac aaggctgtgg
    84901 atgtctttta tgatggacag acctttacta tcctagaaaa tccagttatc caaggccaaa
    84961 atgctggtgc aggttgtacc tttgcctcta gcattgccag tcacttgatt aaaggtgata
    85021 aacttttgcc agcagtagaa agctctaagg ctttcgttta tcgtgctatt gcacaagcag
    85081 atcagtatgg agtaagacaa tatgaagcaa acaaaaacaa ctaaaatcgc ccttgtatcc
    85141 ctattaaccg ccctttctgt ggttctaggt tatttcttaa aaatcccaac acctacagga
    85201 attctaactc ttttagatgc tggtgtcttc tttgcggcct tttactttgg tagtcgtgaa
    85261 ggagcggtag tcggaggact agcaagtttc ttgattgacc tcttatcagg ctaccctcag
    85321 tggatgttct ttagcttggt caaccatggc ttgcagggat ttttcgcagg atttaaagga
    85381 aaaagtcagt ggttaggcct tattttagca actattgcca tggtaggagg ctacgccttg
    85441 ggttctactt tgatgaatgg ctgggcagca gccctcccag aaattctacc aaatttcatg
    85501 caaaatatgg tagggatgat tgtaggattt attcttagtc aaagtatcaa gaagattaag
    85561 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    85621 gttttgagca gcctgcggct agctttctag tctgattttc attgagcata aagaggttga
    85681 gtaaaaagtc tttcaaataa gaaaaacgca tagtatcagg tgttgaatga acacctgata
    85741 ctatgcgttt tattgtggga agattttcct cattttctag tgaaattgaa ctttttctaa
    85801 catcttttga tagatgactt cttaatcaat tatcatttcc attgttgttt cttggggttt
    85861 catcccttgt ctttgataaa agcggagagc accctcgtta tcattccaga cacttagggt
    85921 tagattattg cagccaattt ctttagcata atagcagaaa aatgacaata aaatagcccc
    85981 tagatatttt gaaaggaaag cataggggct atatagttta atcaaaataa agcaaatctt
    86041 tgctggtgct tgtaaagagg tcgaagccat ccttggtaac aacaccgcag tcttcaatac
    86101 gaacaccgac tttaccaggg atatagatac ctggttcaac agagaagcac atgccttctt
    86161 cgatgaccat gtcgtttcct tccatgatag atgggaattc atggacatcc ataccgatac
    86221 catgcccgag acggtggttg aagtactcac cataaccagc tttttcgatg acctcacggg
    86281 cagcgcggtc cacttcatga gcagtcacac ctggcttgat aaagtcaaga gcagcttgtt
    86341 gggcttcaag agtcaagttg taaatatctt tcttgaattg gtctggtttg ccgacagcga
    86401 ctgtacgagt catatctgac gcatagccat tgaccagaac acccaggtca aagaggagaa
    86461 gagcatcatt ttcaacctta ttagctgctg gaatgccgtg tggattcgca gcattatcac
    86521 cagtcaagac catggtatca aagctcattt cgtaaccttc acgtttcatg gcaaagtcaa
    86581 tttgtgcgat gatatctgtc tcagtcttat caagagaaat attgtcaaaa ccaacatgaa
    86641 cagccttgtc agcataaaga cctgcaacca tcattttttg cacttcatca gctgatttga
    86701 tgaggcgcat gcgttggata cgaggagtga ggttgtcaaa ctcagcagtc tcaaaaactg
    86761 ttttcaaacc atggtatttg gtcaagatga gattgtcaaa ctcaacagcg acacgtttga
    86821 agtcaagttg tggaagagca tgtttgattt tttgccatgg attttcagaa tcgacatagc
    86881 ccactactgg gaaggaaacg gtgctacttg cacgttctac ttcaagagct gggacaaaga
    86941 ggagaggttc ctgatctgct aggacaaaga ggaacatttg gcgttcatgg ggatcactgt
    87001 aaaaaccagt gaggtaattg attgtgacgg ggtcagatac gacagcgacg tctagttttt
    87061 ctgattcaag atatgttagg atttgttgta atttagacat atgctacctt ctttctatcc
    87121 ctctattttg gcaaaaaatg agagaaaatg caagggagaa gggtaaaaga aaagacaaaa
    87181 aactccgaca agataacgga gttctttgat atcattttcc tttgtttaag aaaagtcagc
    87241 cttgcttttg acgtcactgt actcttcagc gatttcttgg ctgaggatat cctcataggc
    87301 agggagttgg atgtcctgac catatttctt cttgagggca gtagtaacta ggcgataagc
    87361 cagattggca ttacgagaga ggataggccc gtggaagtag gaaccaaaga cattcttata
    87421 atgaacccct tcaccgacct tttcttcgtt gtttccattt ccatagacaa cctgtcccag
    87481 cggtttttgg tcatcagaga ggaaggtacg gccttggtga ttttcaaatc catagtaggt
    87541 ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata aaacggttat tggtctggtt
    87601 gagcgtgtag tgtcccatga cccctagccc ttcgatacgt tttcctgaag cttcaacata
    87661 atattgaccc aatagttgga aaccaccgca gatagccaga actacaccgt cgttttggat
    87721 gtagttgtca atgctctctt ttttagcagg taggtcgtct gcaatgatac tttgttcaaa
    87781 gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt tcatcaaagt catcatggag
    87841 agaaacgatg tcaacggtca catgggctcc cagtttttca gccacatact tgagcatgag
    87901 gatgtttcca ttgtccccgt aggtattcat gagatttccg tagaggtggg caatgttgag
    87961 ctgatagggg taattgccat cttttgagga aagtgaagta taaaccatta gttcatctcc
    88021 tttctaacaa tctgacgact agccagcagt tcacgaaatt ccagcatggc agtataagtt
    88081 gccagaatat aggcatgctt gcagtcttga ttctcaatgg tcttgagaac ttgctccaga
    88141 ttactcgttt cagtgatttt ctcagctgga tagccagtca ctcggaggcg acgagcgatt
    88201 tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt ccatgtcagt gatttgttca
    88261 aagtctgcat cccagatcca gctagtgtca attccatctg catagttggc attaaggagg
    88321 acagataggc taaatggata aggtgctagt ttgatcattt cgatagcttg ggttgcaccg
    88381 actggatttt taatcaagac aagggtacat tccttgtcac cgatatgaaa ggtttcttgg
    88441 cgtccaaaga cagcacggct cttgtcaaat ccctgtttga tgagttgcga atcggcacct
    88501 aggaaacggg cgatggccac agcagctagg gcgttataga tattatagag cccgccgatt
    88561 tggataccgt attcttggac gtctatgaca aagcgagagc gattgttggt caactcaacc
    88621 agttttgtca aacgatagtc gagatcagga cgtttacatc cacaaccttc acagatatag
    88681 gtacccaagt ttgcataggt attatgctca tatttgagga tgccttggca gtcaggacag
    88741 agaatccctt cggtattgta gtgagccagt tgggctggtc ctttttccaa gtcaaaacca
    88801 aaatactcta tagggtttgg aatagttggc ttgtagaaaa gtggactgtc tccgttaagg
    88861 agaacagtag cagttggaac tttccgaatg gcatccaata tcatgttata ggtagtatag
    88921 atttcaccga aacggtccat ctggtcacgg aagatattag taatgacaaa aagactaggc
    88981 tggatatagt cacagatacg agatagactg gcttcgtcaa tttcgaggac ggcaatattt
    89041 tttccagttt tagaagattt ggctgttagg aaggttgttg caatccctgt aatcatgttg
    89101 gcaccgcttg gattggttag aacttgacca tagacctctt ttaaaatgcc gacagtgagg
    89161 gcagttgtca gggtttttcc atttgttcca gtgacaacga caatctcgta gttcttagct
    89221 aggttttgta aaatatcttt atcaaattga agggcgactt tacctgggag cgtacttcca
    89281 cggccaagac ggcttaaaat gaagtgggaa gaacgcccag caagaaggcc caaagtagtt
    89341 tttaagttca tgtttctatt atatcataaa agaggagaaa gacagatttg agattccgca
    89401 gaagtaaaaa cagcccaaag agggctgttc gatacgatta aatctcaact taaatcgcaa
    89461 acaagtcatt caagttctca gccaaggttg ggtgagtgaa gatttgtttt gtgaagtaag
    89521 tgtaaggaat cttgttgtcc atagcaacag tgatgatgtt gatgatttct tgagaacctt
    89581 ctgagaagat gcttgctcca agaatttctt ttgtttcagt attgacaaca gctttgaagg
    89641 caccgcgaag gtctccattt acgtgaccac gaggcatggc tgcaacgggg atttccttaa
    89701 cagcgtatgg aagtttcaaa tcagctgctt ggctttcagt caaaccaact tgtgaaagtg
    89761 caggtgtgat gaacatagta tttggcacat tgagacggtc ttcaagtgtg tagctgccat
    89821 ctccagcaag gtagctgtaa acaacacgga agtcatcaag tgaaatgtaa gtaaattgaa
    89881 ggccaccgtt gatatctcca actgcaaaga caccaggaac gtttgtttga cagtgtttgt
    89941 ctactttaat agcaccacgt tcagttagtt caatatctgt attttcaagt tgaagtggtt
    90001 ctacatttgg tttgcgtcca gttgcgtaga gaagggcgtc gaaacggtaa gtttcgtctt
    90061 cagttacgac aagcacttgg tcaccatcgt ttttgatttc agtagtatgg atattttgaa
    90121 gcaattcaat gccatcttct tccatgtatt gtttagcaag agctgcgatg gaaggttctg
    90181 cacgaggaag gaaagtatcc aaggcatcta ggactgtgac cttgcttcca agtttgttgt
    90241 aaaggccggc aaattcaaga ccgatatttc cgccaccaag gattccaagt ttttcaggta
    90301 atttgtccaa gttttggata cctgttgagt caaagatgtt tttgcttgta gcaagtccag
    90361 ggattggcaa gacgtttgaa acagcaccag tgttgatgac gattgtttca gcagtcagtt
    90421 ctttcttttc atcaccagct tggatttcga tgactttatt tgaaaggaag tgagcttccg
    90481 catcaaagat atctacgcct gtaccagcaa cagtcgcata gtttttaccg ttgaggcgac
    90541 cagtgatcgt gtttttagta gcaatcactt cttcaaaaga caagtccttt tcagcagcaa
    90601 ctagcaaggt tttagttggg atacaaccaa tgttgataca agttccaccg tacatagcct
    90661 tgctgcgttc aacgagggca acttttttgc cagctgaagc caatttacct gctagtgttt
    90721 taccagcttt accaaatcca ataacaatta aatcgtatgt taacatttat cttcctccta
    90781 ttcgaatttc attctagcac aagaaaaaaa cttttgcaca attctgctac ggaaaagaca
    90841 gaaaaagata aaaacgcttt ccagacaaaa aactagtaat tttttgacaa gcttgataaa
    90901 ctaaaatcct atctattttt atataagata gaataaatgt tcgaaaatag gaggttttat
    90961 gaaatcgaat cgttatatta ttgcctttgc tggggtcatt ttacacttaa tgctgggttc
    91021 gacttatgct tggagtgttt atcgtaaccc tattattgaa aaaacgggat gggatcaggc
    91081 ttctgttgcc tttgccttta gtctagcaat cttttgtttg ggcttatcgg ctgcatttat
    91141 ggggcgtttg gtagaaaaat ttggtccgag agtcatgggg agtctatctg cttttctata
    91201 cgcaggtgga aatatcttaa caggatttgc aatagaccgt caggagctgt ggttgttgta
    91261 tctcgcttat ggcattttag gtgggcttgg tttgggagca ggctatatta cccctgtgtc
    91321 gacgattata aaatggtttc ctgataaacg tggtctcgca acaggtttag cgattatggg
    91381 gtttggtttt gcttctttat tgactagtcc catagcgcaa cacctcatcg caggggtagg
    91441 gcttgtagaa actttttata ttttaggagc aagttacttt attatcatgc tcctagcttc
    91501 acaattcatt aagcgtccaa atgagcaaga gcttgcaatt ttatcttctt cagggaaaga
    91561 aaaaacagcc tctttgacgc aaggaatggc tgcaaatcag gctctaaaaa gcaatcggtt
    91621 ttatatactt tggattattt tctttatcaa catagcttgt ggtttaggct taatttcagc
    91681 ggcatcgcca atggcacagg agatggctgg cttgtctaca agtcatgcag cagtaatggt
    91741 gggcgtttta gggattttca atggatttgg tcgcttgctc tgggcgagct tatctgacta
    91801 tatcggtcgc cctctaacct ttagtatatt actgcttgtt aatcttttct tttctctctc
    91861 actttggctc tttacagatt ccgttttatt tgtagtcgct atgtctattt tgatgacttg
    91921 ctatggagct ggtttttcat tgatcccagc ttatctcagt gatatttttg gaaccaagga
    91981 attggccgct ctgcatggat atattttaac agcttgggca atggctggtt tagcgggacc
    92041 tattttatta gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt
    92101 tctcatttta tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa
    92161 agaaagtcaa aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt
    92221 cttgtgttat actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc
    92281 aacacgattt tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag
    92341 ccctataggg tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt
    92401 aaacttgtct gctgatttgc tggcagaaat tgaaaaagct ggttttgtag aagctagtcc
    92461 tatccaagaa caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca
    92521 gactggtaca ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga
    92581 agaagcgact atccaagcct tggtcatcgc tccaactcgt gaactagctg tccaaagtca
    92641 agaagaactc ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg
    92701 atcaagcatt gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac
    92761 tccaggtcgc ctcttggact tgattaaacg caaggccttg aaattacaaa acattgaaac
    92821 ccttatcctt gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc
    92881 cattatttcc cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga
    92941 tgccatcaaa cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcagc
    93001 taaggaattg acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa
    93061 atttgacacc atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg
    93121 tcgtaccaaa cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc
    93181 agaaggaatt catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa
    93241 aaatggcaat cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc
    93301 aggtgtgacc catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg
    93361 tatcggtcgt acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa
    93421 cgaaatgggt taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa
    93481 acctgcaagt gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga
    93541 acgtgatttt gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg
    93601 caaattggct gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt
    93661 ccaagaccca gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa
    93721 accatcaggt aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga
    93781 cgaccgtcga gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag
    93841 tcgtggcaac gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg
    93901 caatacttta agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga
    93961 aaaagcggtt caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat
    94021 aaaattatta tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata
    94081 gaaaaggaac aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa
    94141 gtcaataagg aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag
    94201 cgattaaatt cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca
    94261 attttgaaac gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt
    94321 cagttagcgg atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt
    94381 ggctatttta tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag
    94441 attttcccag atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg
    94501 cctgttgagc atgatatgag tattttccct gttgagagta gagatgattt tccagatggc
    94561 ttgacgacta ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg
    94621 cgtaatgata aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt
    94681 gttgggattc agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt
    94741 actgctgtca ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca
    94801 attttagggg aattaaatgg aaatgaaggg cagttgactg cgtcagtgat tgcagatcgt
    94861 atcggaatca ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt
    94921 attgaaagtc gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt
    94981 tttgaagaag tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata
    95041 cagaagattt tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt
    95101 cggatgccat tagcaaggta actcgattag cttttgaacg aggagattat atcttcttta
    95161 ctattgatgc tcatgaagaa aacgattttt tccatccgga aagtaagtta tttcctcctc
    95221 ataatctgat tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag
    95281 agcatggttc agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag
    95341 ggactgacct agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg
    95401 tcttgacgga tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca
    95461 tcgagattgt taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag
    95521 gtcatttcaa aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg
    95581 agtaacctgg ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa
    95641 gttgatatac tagtaaagta atcgatgcgg ggatggcgga attggcagac gcgcaggact
    95701 aaggatcctg tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa
    95761 gagttagcta aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta
    95821 gtggagaatc agcgaaaata tgggaaaact gatccttgtt tctgcttttg tcatagaaga
    95881 ataataaaga ttatcttctt caaattctcc gatattctct aaagttttgt gcaagttgca
    95941 cagaactttt ttattttttt ggtcatcttg ccatagaaat ataaagcgtt ttcatatata
    96001 atataattat caaaagacaa aaggagttca cctcatggta gaattgaatc ttaaaaatat
    96061 ttacaaaaaa tatccaaaca gcgaacacta ttcagttgaa gatttcaact tgaacataaa
    96121 agataaagaa tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg
    96181 tatgattgct ggtcttgaag acattacaga aggtactgca tctatcgatg gcgtggttgt
    96241 caacgacgta gctccaaaag accgtgatat cgccatggta ttccaaaact acgctcttta
    96301 cccacacatg actgtttatg acaacatggc tttcggcttg aaattgcgta aatacagcaa
    96361 agaagacatt aacaaacgtg ttcaagaagc agctgaaata cttggattga aagaattctt
    96421 ggaacgtaaa ccagctgacc tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc
    96481 gattgtccgt gatgcgaaag tattcttgat ggacgaacct ttgtcaaact tggatgccaa
    96541 acttcgtgta tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac
    96601 tatctatgta actcacgacc aaacagaagc gatgacactt gcagaccgta tcgttattat
    96661 gtcagctact aagaaccctg ctggtacagg tactatcgga cgtgtagaac aaatcggtac
    96721 tcctcaagaa gtttacaaaa atccagttaa caaattcgtt gcaggattca tcggaagccc
    96781 agctatgaac ttcatcaccg tgaaattggt tggtagcgaa attgtttctg acggtttccg
    96841 tttgaaagtg ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga
    96901 attgatcttt ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt
    96961 cccagactgt gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt cagaatctca
    97021 cctttactgc caagttggta aagacgagtt tgttgcaaaa gttgatgctc gtgactactt
    97081 gcaaacaggt gcaacagttg agcttggatt tgacttgaac aaagcacact tcttcgatgt
    97141 agaaactgaa aaaacaatct actaaaataa ataaaattca aagcactaca agaaaagata
    97201 tctctttatc aattgtagtg gagagatatc agttaatcta gggagagaaa caaaatgctt
    97261 ctctcctttt tgctagggaa gtcatattat gcatctatat tgtgatgctc tttatactct
    97321 tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt acgtatgatt actgatttcg
    97381 tcagttttat ctgcaacctc aaagatgtac tttgagcagc ttacggctag tttcctagtt
    97441 tgctctttga tttccattga gtattattgt gagtaccatc tacaagtgaa gctatatgcg
    97501 taaactacgt gagcaattga attcgaacta gagaggtaat aataaattta tgctatagtt
    97561 atggtgactt gtatgctttt gattctagtt tatcaaataa tagattagaa ttgtcagata
    97621 atatcatttt gtgttataat gaagaaaaaa cagaggtgtt caaatgtcag aagcaggtca
    97681 taagttttta gcaaaattgg ggaaaaaacg cttacgtcca ggtggaaagc gtgccacaga
    97741 ttggttaatt gcagaaggag gattttcaaa agaaaagaga atactagagg ttgcgtgtaa
    97801 taggggaact acagcaattg agttggcaca gcgttttggt tgcaagataa ctgctgttga
    97861 tatggatgct caagctttag aagtggctaa aaaatctgct ggaacggcag gtgttgctca
    97921 tttaatcagt tttgaaagag caaatgcaat gaaacttcct tatcaagatg ctagttttga
    97981 tattgttata aatgaagcta tgctgactat gcaagccgat caagctaaga aaaaatgtgt
    98041 aatggaatat ctaagggtat taaaacctgg aggtcttctc ttgacacatg atgtgcttct
    98101 taaggaagct aaagagtcta tcagacagga attatcacaa gcaattcatg taaatgtagg
    98161 tcctttaact caagatggtt gggaacaggt gatgatagaa tcaggttatt gtgatgtgaa
    98221 agcattgact ggtgaaatga cattaatgaa attatcgggt atgatttatg acgaaggttt
    98281 gctaggaact ttgaaaattt gtgtaaatgc ttgtaaaaag gagaatagaa agcagttttt
    98341 aactatgtat aaaatgtttg ctaagaataa acagaaattg ggctttattg cgatggctag
    98401 ttataaatcg tcaaaacgtt agataattat tgaagttaac ttttcctttt ttctttctta
    98461 aaaaatatgc tataatagag agtaaaaaac tttgaaagaa agaaaaaaga tgaatttaaa
    98521 agattacatt gcaacaattg aaaattatcc aaaggaaggc attaccttcc gtgatattag
    98581 tcctttgatg gctgatggaa atgcttatag ctacgctgtt cgtgaaatcg ttcagtatgc
    98641 tactgacaag aaagtcgaca tgatcgtggg acctgaagct cgtggattta tcgtgggttg
    98701 tccagttgcc tttgagttgg gaattggttt tgcgcctgtt cgtaagccag gtaaattgcc
    98761 acgtgaagtt atttctgctg actatgaaaa agagtacggt gtcgatacct tgactatgca
    98821 cgcggatgcc attaagccag gtcaacgtgt tcttattgta gatgaccttt tggcgacagg
    98881 tggaactgtt aaggcaacta tcgagatgat tgaaaaactt ggtggtgtta tggcaggttg
    98941 tgccttcctt gttgaattgg atgaattgaa cggccgtgaa aaaattggtg actacgacta
    99001 caaagttctt atgcattatt aatgaaaaca gtccctaggg ctgttttctc tacactagga
    99061 tataaaaata gactataact agttagagaa aaactataat tgaaaactat atcttcttgc
    99121 agtataataa aaggactaag tgtttgagat ttgtcttcaa acatatgcaa ttattcctga
    99181 aagagtacag ttaggagagg gttatgccga ttcgaattga taaaaaattg ccagctgttg
    99241 agattttacg gacagagaat atctttgtca tggatgatca acgtgctgcc caccaagata
    99301 tccgtccttt gaagatttta attttaaatc tcatgccaca gaaaatggtc acagagaccc
    99361 agttgttgcg ccacttggct aatacacccc tacaactgga tattgatttt ctctatatgg
    99421 agagccaccg ttctaaaaca actcgttcag agcacatgga gaccttctat aaaacttttc
    99481 ctgaagtcaa ggatgagtat tttgatggga tgatcatcac gggtgctcca gttgagcatt
    99541 taccatttga ggaagtggac tattgggagg aatttagaca gatgcttgag tggtctaaga
    99601 ctcatgtcta ttcgaccctt catatctgtt ggggggctca ggctgggctt tatctgcgct
    99661 atggtgtaga aaaataccag atggacagta agctatcagg tatttatcct caggacaccc
    99721 taaaagaggg tcaccttcta tttagaggct ttgatgatag ctatgtatcc cctcattcac
    99781 ggcacacgga gatttctaag gaagaggtct taaacaagac caatctcgag attttatcag
    99841 aaggacctca ggttggggtt tctattttgg ccagtcgtga tttacgagaa atttatagtt
    99901 ttggtcattt ggagtatgac cgtgatacct tggcaaaaga gtattttcga gatcgtgatg
    99961 caggtttcga cccacatatt ccagaaaatt actttaaaga tgatgatgtt aatcaggtac
   100021 cttgtctttg ttggtcttca tctgcagccc tctttttcag taattgggta aaccatgcgg
   100081 tctatcagga gacgcctttt gattggagaa agatagaaga tgatgcatct gcatatgggt
   100141 atttataaga ggaattatga catatttaga cgcttttaaa tcaggtacct tggttttacc
   100201 gagtgccctg ctcttgcatt ttaaggaact ctttccttct agcgacgatt ttctggtttg
   100261 gcaatttttc tatttgcaaa atacgacagg cttagaagaa atgtcgccaa gccagattgc
   100321 tgaaaggatt ggcaaggaaa tttcggatgt caaccagtcc atttctaatc tgacggaaag
   100381 gggactgctc cagtatcgta ctatcgaatt aaatggcgaa attgaattgc tctttgatgc
   100441 tagtttggcc ttggaacgtt tggatgacct gtttggagca gttcattcaa gttcagacca
   100501 gctaacacct caaaaccagc tcaaggattt ggtggaaacc ttccagcagg agttgggacg
   100561 attgttgacg ccttttgaga ttgaggattt gaccaagaca ctaaaggaag atggaaccag
   100621 tgctgacttg attaaggagg ctcttcgtga agctgttttg aatggaaaac caaactggaa
   100681 gtacattcag gctattttga gaaactggcg ccatgaagga atcaagagtg tggctcaaat
   100741 tgaggccaag agagcagaaa gagaagcaag caatcctcag ttgacacagg tatctgcaga
   100801 tttcagaaat gccatggatc tctggaagga ttaatccatg caagtaggct tgaaatccga
   100861 gtaagatttg caagctgtgt ataattgtga tagaataaat agaaaataaa ttgaaaaaag
   100921 aggtatgtga aatgtcacgt aaaccattta tcgctggtaa ctggaaaatg aacaaaaatc
   100981 cagaagaagc taaagcattc gttgaagcag ttgcatcaaa acttccttca tcagatcttg
   101041 ttgaagcagg tatcgctgct ccagctcttg atttgacaac tgttcttgct gttgcaaaag
   101101 gctcaaacct taaagttgct gctcaaaact gctactttga aaatgcaggt gctttcactg
   101161 gtgaaactag cccacaagtt ttgaaagaaa tcggtactga ctacgttgtt atcggtcact
   101221 cagaacgccg tgactacttc catgaaactg acgaagatat caacaaaaaa gcaaaagcaa
   101281 tctttgcgaa cggtatgctt ccaatcatct gttgtggtga atcacttgaa acttacgaag
   101341 ctggtaaagc tgctgaattc gtaggtgctc aagtatctgc tgcattggct ggattgactg
   101401 ctgaacaagt tgctgcctca gttatcgctt atgagccaat ctgggctatc ggtactggta
   101461 aatcagcttc acaagacgat gcacaaaaaa tgtgtaaagt tgttcgtgac gttgtagctg
   101521 ctgactttgg tcaagaagtc gcagacaaag ttcgtgttca atacggtggt tctgttaaac
   101581 ctgaaaatgt tgcttcatac atggcttgcc cagacgttga cggtgccctt gtaggtggtg
   101641 cgtcacttga agctgaaagc ttcttggctt tgcttgactt tgtaaaataa tcagtaagta
   101701 gcaaaagcta ggtggaacag cattcagatg tctgttacat tttttatagg agagcaaaga
   101761 ttgaaaacaa aaattggatt agcaagtatc tgtttactag gcttggcaac tagtcatgtc
   101821 gctgcaaatg aaactgaagt agcaaaaact tcgcaggata caacgacagc ttcaagtagt
   101881 tcagagcaaa atcagtcttc taataaaacg caaacgagcg cagaagtaca gactaatgct
   101941 gctgcccact gggatgggga ttattatgta aaggatgatg gttctaaagc tcaaagtgaa
   102001 tggatttttg acaactacta taaggcttgg ttttatatta attcagatgg tcgttactcg
   102061 cagaatgaat ggcatggaaa ttactacctg aaatcaggtg gatatatggc ccaaaacgag
   102121 tggatctatg acagtaatta caagagttgg ttttatctca agtcagatgg ggcttatgct
   102181 catcaagaat ggcaattgat tggaaataag tggtactact tcaagaagtg gggttacatg
   102241 gctaaaagcc aatggcaagg aagttatttc ttgaatggtc aaggagctat gatgcaaaat
   102301 gaatggctct atgatccagc ctattctgct tatttttatc taaaatccga tggaacttat
   102361 gctaaccaag agtggcaaaa agtgggcggc aaatggtact atttcaagaa gtggggctat
   102421 atggctcgga atgagtggca aggcaactac tatttgactg gaagtggtgc tatggcgact
   102481 gacgaagtga ttatggatgg tgctcgctat atctttgcgg cctctggtga gctcaaagaa
   102541 aagaaagatt tgaatgtcgg ctgggttcac agaaacggta aacgctattt ctttaataat
   102601 agagaagaac aagtgggaac cgaacatgct aagaaaatca ttgatattag tgagcacaat
   102661 ggtcgtatca atgattggaa aaaggttatt gatgagaacg aggtggatgg tgtcattgtt
   102721 cgtctaggtt atagcggtaa agaagacaag gaattggcgc ataacattaa ggagttaaac
   102781 cgtctgggaa ttccttatgg tgtctatctc tatacctatg ctgaaaatga gaccgatgct
   102841 gagaatgacg ctaaacagac cattgaactt ataaagaaat acaatatgaa cctgtcttac
   102901 cctatctatt atgatgttga gaactgggaa tatgtaaata agagcaagag agctccaagt
   102961 gatacagaca cttgggttaa aatcatcaac aagtacatgg acacgatgaa gcaggcgggt
   103021 tatcaaaatg tgtatgtcta tagctatcgt agtttattac agacgcgttt aaaacaccca
   103081 gatattttaa aacatgtaaa ctgggtagcg gcctatacga atgctttaga atgggaaaac
   103141 ccttattatt caggagaaaa aggttggcaa tatacctctt ctgaatacat gaaaggaatc
   103201 caagggcgcg tagatgtcag cgtttggtat taagcgatga tttgaaagag ggatgtgata
   103261 gtagcaccct ctttttcttt gttttatgat agttcatcct cgagtaaatt caagatcttg
   103321 ctcggaaatg aagcttatat agtagattga atatagacaa ataccttgtg attggtaaaa
   103381 cattttagaa attcatttac ctttcctaat cgacttggtt tcatcttatt tcaatctatt
   103441 atagtattgg ggaatttctt caaaccacat cagcttggtc agttctacct gcgacctcaa
   103501 aacttgtgct ttggtcaagc tgggtttagt ttcctagttt gctgatggat ttccattgac
   103561 tataagcatc caaccctctt tttgtcttct aaagaattct taaattatca gtctattgca
   103621 acttttctca tataagttct ttgtcttgct atttgttttc cttagtagta tactaaggta
   103681 gtaatcatta agaagtggtt acaaaaaata atgaatgagg taaagaaaat ggtagaattg
   103741 aaaaaagaag cagtaaaaga cgtaacatca ttgacaaaag cagcgccagt agcattggca
   103801 aaaacaaagg aagtcttgaa ccaagctgtt gctgatttgt atgtagctca cgttgctttg
   103861 caccaagtgc actggtatat gcatggtcgt ggtttccttg tatggcatcc aaaaatggat
   103921 gagtacatgg aagctcttga cggtcaattg gatgaaatca gcgaacgctt gattacactc
   103981 ggtggaagcc cattctctac attgacagag ttccttcaaa atagtgaaat cgaagaagaa
   104041 gctggtgaat accgtaatgt tgaagaaagc ttggaacgtg ttcttgttat ctaccgttac
   104101 ttgtcagaac ttttccaaaa aggtttggat gtcactgatg aagaaggtga cgatgtgaca
   104161 aacggtatct ttgcaggcgc taaaactgaa acagataaaa caatttggat gcttgcagcc
   104221 gaacttggac aagcacctgg tttgtaagaa ataaggaaac atagataaat ctgtaggaaa
   104281 tttcttacag attttttcta ttttgtaagc tattccaaac cagtcttttt ttgagttttt
   104341 tgataaaata gtactatcag tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt
   104401 tgggcccagg atgaagaggg tgtgattggt aaggaaaatc gtctgccttg gcatttgcca
   104461 gcagaattgc agcactttaa agaaacaact ctgaatcatg ctatcttgat ggggcgtgtg
   104521 acctttgatg ggatggggcg tcgcttgctt ccaaaacggg aaaccctgat tttgacgcgt
   104581 aatccggaag aaaagataga tggggttgct acttttcagg acgtccagtc tgttcttgac
   104641 tggtatcagg atcaagaaaa gaatctctac attatcggtg ggaagcaaat ttttcaggct
   104701 tttgaacctt accttgatga agtgattgtc actcacattc atgctcgggt ggaaggagat
   104761 acctatttcc ctgaagagct tgacttgtct ctttttgaga cagtttcaag caaattttac
   104821 gccaaagatg agaagaatcc ttatgatttt accatccaat accgcaagag aaaggaagta
   104881 taatggaacg gagtttattt ggtctattca cggcttttct gtgtttcatc tgctttctgg
   104941 caggagcaca ggcttttcgt aaaaagcgtt acgggctttc tatcctcctt tggttaaatg
   105001 cctttaccaa tctggtcaat agtattcatg ctttttacat gaccttattt tagatagaat
   105061 gacagtatag aatggaagga aatcatgtct acaaatagaa aaaatgatat gatggtttat
   105121 tgctcatttt gtggcaaaaa ccaagaagaa gtacaaaaaa taattgctgg caacaatgct
   105181 tttatttgta atgaatgcgt ggagttagct caggaaatca ttcgagaaga attggttgag
   105241 gaagtcttgg cagacttgtc tgaggtgcca aaaccaattg aactcctcca tatcttgaac
   105301 cactatgtaa ttggtcaaga tcgtgccaag cgtgccttgg cagtggcggt ttataaccac
   105361 tacaaacgca tcaatttcca cgatacacgc gaagagtcag aagatgtgga tttgcagaag
   105421 tcaaacattt tgatgattgg cccaactggt tcagggaaaa ctttccttgc ccagaccttg
   105481 gctaagagct tgaatgtgcc ttttgctatt gcggatgcga cagctctgac ggaggctggt
   105541 tatgtgggtg aggacgtgga aaatatcctc ctcaaactct tgcaggttgc tgactttaac
   105601 atcgaacgtg cagagcgtgg cattatctat gtggatgaaa ttgacaagat tgccaagaag
   105661 agtgagaatg tgtctatcac acgtgatgtt tctggtgaag gggtgcaaca agcccttctc
   105721 aagattatcg agggaactgt tgctagcgtg ccgcctcaag gtggacgcaa acatccacaa
   105781 caagagatga ttcaagtgga tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat
   105841 ggtattgaag aaattgtcaa acaacgtctg ggtgaaaaag tcatcggatt tggtcaaaat
   105901 aataaggcga ttgacgaaaa cagctcatat atgcaagaaa tcatcgctga agacattcaa
   105961 aaatttggta ttatccctga gttgattgga cgcttgcctg tttttgcggc tcttgagcaa
   106021 ttgaccgttg atgacttggt tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa
   106081 taccaaactt tgctttctta tgatgatgtt gagttggaat ttgacgacga agcccttcaa
   106141 gagattgcta ataaagcaat cgaacggaag acaggggcgc gtggacttcg ctccattatc
   106201 gaagaaacca tgctagatgt tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt
   106261 cgcatcacta aagaaactgt cgatggaacg gataaaccga tcctagaaac agcctagagg
   106321 tgactatgga acttaataca cacaatgctg aaatcttgct cagtgcagct aataagtccc
   106381 actatccgca ggatgaactg ccagagattg ccctagcagg gcgttcaaat gttggtaaat
   106441 ccagctttat caacactatg ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg
   106501 gtaaaaccca gctcctgaac ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc
   106561 ctggttatgg ctatgctcgt gtttctaaaa aggaacgtga aaagtggggg tgcatgattg
   106621 aggagtactt aacgactcgg gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc
   106681 atgacccgtc agcagatgat gtgcagatgt acgaatttct caagtattat gagattccag
   106741 tcatcattgt ggcgaccaag gcggacaaga ttcctcgtgg taaatggaac aagcatgaat
   106801 cagcaatcaa aaagaaatta aactttgacc cgagtgacga tttcatcctc ttttcatctg
   106861 tcagcaaggc agggatggat gaggcttggg atgcaatctt agaaaaattg tgaggaaaag
   106921 aaaatggcaa aaacaattca tacagataag gccccaaagg ctatcggacc ctatgttcaa
   106981 ggaaaaatcg ttggcaacct tttgtttgct agcggtcaag ttcccctatc ccctgaaact
   107041 ggggaaattg taggagagaa tatccaagaa cagacagagc aagtcttgaa aaacatcggt
   107101 gctattttgg cagaagcagg aacagacttt gaccatgttg tcaaaacaac ttgtttcttg
   107161 agcgatatga acgactttgt tccttttaat gaggtttacc aaacggcctt caaagaggaa
   107221 ttcccagctc gttcagctgt ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt
   107281 gaagtcatcg cagagattgg ataagctagt tgaagtttgg tgttgccaaa cttcttttga
   107341 tataaggaga aaaagatgac aaagaaacaa cttcacttgg tgattgtgac agggatgagt
   107401 ggcgcaggga aaactgtagc cattcagtcc ttcgaggatc taggttattt caccattgat
   107461 aatatgccgc cagctctctt gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat
   107521 cctaagttgg ccttggtagt ggatatgcgt agccgttctt tcttttcaga gattcaagct
   107581 gttttggatg agttggaaaa tcaagatggt ttggatttca aaatcctctt tttggatgcg
   107641 gctgataagg aattggtcgc tcgttacaag gaaaccagac ggagtcaccc actagcagca
   107701 gacggtcgta ttttagatgg aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat
   107761 atgagccaaa atgtggtgga tacgactgaa ctcactccac gtgagctgcg caaaaccctt
   107821 gcagagcagt tttcagacca agaacaagcc cagtctttcc gtatcgaagt catgtctttc
   107881 ggatttaagt atggaatccc gattgatgcg gacttggtct ttgatgtccg tttcttgcca
   107941 aatccctatt atttaccaga actgagaaac caaacgggtg tggatgaacc tgtttatgat
   108001 tatgtcatga accatcctga gtcagaagac ttttatcaac atttattggc cttgattgag
   108061 ccgattctgc caagttacca aaaggaaggt aagtccgttt tgaccattgc catgggatgt
   108121 acgggtggac aacaccgtag tgtggcattt gctaaacgct tggtgcagga cttatccaag
   108181 aattggtctg ttaatgaagg gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt
   108241 tcatgagaaa accaaagata acggtgattg gtggagggac tggaattccc gtcattctaa
   108301 aaagtctgcg ggaaaaagat gtggaaatcg cagctatcgt gacggtggca gatgatggtg
   108361 gttcttcagg tgaactccga aaaaatatgc aacagttgac accgccaggt gattttcgta
   108421 atgtccttgt ggccatgtcg gatatgccta agttttatga gaaggtcttt cagtatcggt
   108481 tctctgagga tgccggagcc tttgctggcc atccattggg aaatctcatc attgctggct
   108541 tgtcagaaat gcagggttca acctataatg ccatgcagtt attgagcaaa tttttccata
   108601 caacagggaa aatttatcct tccagtgacc atcctttgac ccttcatgca gtctttcagg
   108661 atgggacaga agtggctgga gagagtcata ttgtagacca tcgaggcata attgacaatg
   108721 tctatgtgac caatgcccta aacgatgata cgcctctggc cagccgtcga gtagtgcaga
   108781 ccatccttga aagtgacatg attgtcctag ggccaggttc tctctttacc tctattttgc
   108841 ccaatatcgt gattaaggaa attgggcggg ctcttttgga aaccaaggca gaaattgcct
   108901 atgtctgcaa tatcatgacc caacgtgggg agacggaaca ctttacagat agcgaccacg
   108961 tggaagtctt gcatcgtcac cttggtcgcc cttttatcga cactgtcttg gtgaatattg
   109021 aaaaagtgcc tcaggaatac atgaattcca accgttttga tgaatacttg gtgcaagtgg
   109081 aacacgattt tgtaggtctt tgtaagcaag tttcgcgcgt gatttcatct aacttccttc
   109141 gtctggaaaa tggcggtgcc ttccacgatg gagatttgat tgtggacgag ttgatgcgca
   109201 ttatacaggt gaaaaaatga gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca
   109261 ccatctgagc tggcatgaat tatctgccat tatcaaaatg tctggtagca tcggtctctc
   109321 gacttcgggc ttgactttgt cagttgtgac agaaaatgcc aaactggccc gtcacctcta
   109381 tgagtccttt ctccatttct atgaaatcaa atctgaaatt cgtcaccacc aacggagcaa
   109441 tcttcgcaag aatcgcgtct ataccgtttt tacagatgaa aaggtgcagg atttgttaag
   109501 tgatttgcac ttggcagact ctttctttgg cctggaaaca ggtattgatg aggcgatttt
   109561 atcggatgag gaagcaggtc gtgcctatct ctgtggcgct ttcttggcaa atgggagcat
   109621 tcgtgaccct gagtcaggca agtaccagtt ggaaatcagt tctgtttatc tggaccacgc
   109681 gcaaggaatt gcctcccttc tccaacagtt tttactggat gccaaggtgc ttgagcgcaa
   109741 gaagggggct gtgacctatc tccagcgagc agaagacatt atggacttct tgatagtaat
   109801 cggagccatg caggcacgtg atgattttga gcgggttaag attttgcgag aaacccgtaa
   109861 cgacctcaat cgggctaata atgccgagac agctaatatc gctcggacag tttctgccag
   109921 catgaagacc attaacaata tcagtaaaat aaaagatatc atgggcttag aaaatttgcc
   109981 agtagatttg caggaagtgg cgcaactgag gattcagcac ccagactact ctatccaaca
   110041 gttggcagat agcctcagca cccctctgac caaaagtggt gtcaatcaca gactcagaaa
   110101 aatcaataag atagccgatg aattataaaa ccacgaatcc tatgtgactc gtggttcttt
   110161 tttataaact agtagagtgt tttggttgta ctttttgttc agggtcaatg tagttgatag
   110221 cgttgttgac agcagttgga gcttctccga ggcctgtcgc aatcagatca atttttccgt
   110281 catagtagca gcagtcaccg atagcataga tacctgcttg gctggattcc tgtttgctgt
   110341 tgacgataat cttgtgacgg ttgaggtcga gcccccagtt tttaaggtta ccgacagaag
   110401 atttgaaacc atagttgaca aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt
   110461 tgacttttgt gatttcaagt ttatcaagtg tttttccatt tccaaggagt tggctagggg
   110521 cgaatggtgt cttgatggtt acagatgatt cttgcaaggc ttgaacactg tgttccaagg
   110581 cacggaaatt atctctgcgg tgaacaaggg tagttggtgc gattttttca aaagccaaag
   110641 cccaatccac agccgagtct cccccaccaa gaatcgtcac tttcttacca gcgtattgct
   110701 gaatgttaga aacgtggtag tggatatttt catagccctc aacactttca agttccagcg
   110761 gacgtggttt gaaggcaccg ccacccatag cgatgataac tgttttagtc aggtgacttc
   110821 ctttagaagt tgtgatggca aattcttctt cttgtttgtc aatctcaaga accgtttcat
   110881 tgagatgaat aggggtatca aatccattta gctgttcaat caagcggtta gtcaactctt
   110941 ctccagtcag gtttgggaag cctggtacgt ctaggatttc cttttcaggg tagagaatag
   111001 caggttgtcc acctagctgg ggaagagagt cgatgatttg aaccttggct tggcgtaggt
   111061 gggcataaaa ggctgcaaaa agcccgacag gaccaccacc cacaatggta atatcataga
   111121 gttgagacat agtttctcct ttgttttttc tagtcagttt attttatcat atttttgttc
   111181 aatgtaaaat ggactaggat agggaaaaaa atgccagaaa atggtataat aggacgaaag
   111241 tgttttgata gggaggatat cagggatgaa ttttcaacaa ttatccaatc tgcaatattg
   111301 gaccagtttg tttgcaagtc catggacgat agctatcaat ctgattgata ttttgattgt
   111361 tgcttatatt ttataccatt ttacaaaagc tattgcagga accaagatta tgattttggt
   111421 acgtggagtt ttggtgttta ttttagctca aatccttgca aatatgattg gtttgactac
   111481 gatttcttgg ttaatcaatc aaattattac ttatggggtt attgcggcgg ttgttatctt
   111541 ctctccagag attcggactg gtttggaacg tttgggaaga gcgacagatt tcttttccaa
   111601 tgcccctatt agtgctgagg aacagatgat tcgtgccttt gttaagtctg ttgaatacat
   111661 gagtcctcgt aaaatcgggg ccttggttgc tattcagcgt gtacgtacct tgcaggagta
   111721 tatgtcgaca ggaattccct tggatgctaa gatttctgca gaacttctca ttaacatttt
   111781 tattcccaac actcccctac atgacggtgc ggtgattatc aaagaagaac gtatcgctgt
   111841 gacgtctgcc tatctgccct tgacaaaaaa cacagggatt tccaaggaat ttgggaccag
   111901 acaccgggcg gctatcggtt tatcagaagt ctcagatgcc ttgacttttg tcgtatcaga
   111961 ggaaacggga ggaatttcga taacctataa tggaaggttt aagcacaacc taacacttga
   112021 tgaatttgaa acagaattac gtgaaatctt acttccaaaa gaggaagtgg gtcttagttt
   112081 taaagaacga ttgctaggag gatggaaaca tgaaaaaaaa tagtttatat atcatatcct
   112141 cactcttttt tgcttgtgtc ttatttgtct atgctacggc gacgaatttt caaaacagta
   112201 ccagtgctag gcaggtaaaa acggaaacct atactaatac agtaacaaat gtccctattg
   112261 acatacgcta taatagtgat aagtatttta ttagcggttt tgcttcagaa gtatcagtgg
   112321 tcttgactgg tgcaaatcgc ctatcgctag ctagtgaaat gcaagaaagt acacgtaaat
   112381 tcaaggttac tgctgaccta acagatgccg gtgttggaac gattgaagtt cctttgagca
   112441 ttgaagattt acccaatggg ctgaccgctg tggcgactcc gcaaaaaatt acagtcaaga
   112501 ttggtaagaa ggctcaaaag gataaggtaa agattgtacc agagattgac cctagtcaaa
   112561 ttgatagtcg ggtacaaatt gaaaatgtca tggtgtcaga taaagaagtg tcgattacga
   112621 gtgaccaaga gacattggat agaattgata agattatcgc tgttttgcca actagcgaac
   112681 gtataacagg taattacagt ggttcagtac ctttgcaggc aatcgaccgc aatggtgttg
   112741 tcttaccggc agttatcact ccgtttgata caataatgaa ggtgactaca aaaccagtag
   112801 caccaagttc aagcacatca aattcaagta caagcagttc atcggagaca tcttcgtcaa
   112861 cgaaagcaac tagttcaaaa acgaattaaa aatagaaaag gattttataa caatgggtaa
   112921 atattttggg actgatggag tccgtggaga agctaaccta gaactaacac cagaattagc
   112981 ctttaaacta ggacgttttg gaggctatgt tcttagtcaa catgaaacgg aagcgccgaa
   113041 agtctttgta ggacgtgaca cacgtatttc aggggaaatg ctggaatcgg ccttggtggc
   113101 aggtctcctt tcagtaggga ttcacgtata caaacttggt gtccttgcaa caccagcagt
   113161 agcttacttg gttgaaactg aaggagcaag tgccggtgtc atgatttctg ctagccacaa
   113221 cccagccctt gataacggaa tcaagttctt tggcggtgat ggcttcaaac tagatgatga
   113281 aaaagaagca gaaattgaag ccttgctaga tgctgaggaa gacactcttc ctcgtccaag
   113341 tgcagaaggc ttaggaattt tggtagatta tccagaaggc ttgcgtaagt atgaaggata
   113401 ccttgtttca actggaactc ctcttgatgg aatgaaggtt gccttggata cagctaatgg
   113461 agcagcttct accagtgccc gtcaaatctt tgcagacctt ggtgcccaat tgacggttat
   113521 cggggaaaca ccagacggtc ttaacatcaa ccttaatgtt ggttcaacac atccagaagc
   113581 ccttcaagaa gtggtcaaag aaagtgggtc agctattggt ttggcctttg atggagacag
   113641 tgaccgcttg attgctgttg atgagaatgg taacatcgtc gatggtgaca agattatgta
   113701 catcatcgga aaataccttt ctgaaaaagg acaattggct caaaatacaa ttgtgacaac
   113761 tgttatgtct aaccttggtt tccacaaggc cttgaatcgc gaaggtatta acaaggcagt
   113821 tactgcagtt ggtgaccgct acgttgttga agaaatgaga aaatcaggct acaaccttgg
   113881 tggtgaacag tctggtcacg ttatcttgat ggattacaat accacaggtg atggtcaatt
   113941 atcagcagtt caattgacta aaatcatgaa ggaaactggt aagagcttat cagagttggc
   114001 ggcagaagta acgatttatc cacaaaaatt agttaatatc cgagtggaaa acgtcatgaa
   114061 ggaaaaggcc atggaagtgc cagctatcaa ggccatcatc gagaagatgg aagaagaaat
   114121 ggcggggaac ggccgtatcc ttgttcgtcc aagtggaaca gaacccctct tgcgtgttat
   114181 ggcagaagcg cctacaacag aagaagtaga ctactatgtt gataccatca cagatgtagt
   114241 tcgtgctgaa attgggattg actaaatcct agaaaactag atgaaaataa aaaattatgg
   114301 tacaatagct tataatattg tagccgatgg agaaagacat gaatcttaaa cgtgaacaag
   114361 aatttgttag tcagtatcat tttgatgcgc gtaattttga atgggaaaat gaaaatggag
   114421 ctcctgaaac caaggtggat gtgaatttcc aattgctcca acatgaccaa gaaaatcaag
   114481 tgacttcctt gattgtcatc ttgagcttta tgattgtatt tgataagttt gtcattagtg
   114541 gaacaatctc acaagtaaac catatcgatg gccgtattgt caatgaacca agtgaattga
   114601 accaagaaga ggtggaaacc ttggctcgtc catgtttgaa catgctcaat cgtttgactt
   114661 acgaagtgac tgaaattgca ttagacttac caggaattaa tttggagttc taatatgaaa
   114721 ttagctgttt tcacagattc ctctgcttat ctcagtgaag agaccttgca aagagaagac
   114781 ttgtttgtct tggatattcc tgtcaatatt gatggtgagg aatatgtcga aggcatcaat
   114841 ctgtctgctg aggaatttta ccaaaaaatg gctcaggctt ctgaattgcc taagaccagt
   114901 caaccaagta ttgccaagtt agatgagatc ttaacttcgc tcaaagaaca aggctataca
   114961 catgccttgg ggcttttcct atcttctgga atttcaggtt tttaccaaaa tatccagtat
   115021 atggtcgatg actatgaggg cttaaccatt gctttcccag acactttgat tacaagtgct
   115081 cccctaggca tcatggttga aagcgtcttt aattggcgtg atcagggcga tgattttgcc
   115141 agcattcagg ataagctagc cattcaaatc agccgtacgt cagcctttat catggtagat
   115201 gacttggatc atttggtaaa aggtggacgc ctttcaaatg gggctgccat tttgggcaat
   115261 ttgcttagca ttaagccaat cctttatttt aacgatcaag gtgtgattga agtttacgaa
   115321 aaagttcgta ctgaaaagaa ggccaccaag cgcttaattg aaattatcaa ggaaacaacg
   115381 gcttcaggtc aataccgggt cattgtcatt catgggaatg ctcctgaaaa ggctgaagaa
   115441 ttgcgtcagc acttgcttga ttttggcttg ggttcggatg tttcacttgc tacatttggt
   115501 agtgtcattg gaacgcacct aggagcagga agtattgctc tgggttatat tccagtgatt
   115561 tagttggcgc ttctaggcta gttaagatgc cttgtatctt agaaattgaa cacggactac
   115621 ctgcctcttg aaaaaagatg cctgtcttgc ctttcgtgga aagtcagtgc cattccctat
   115681 ttttcagagg cagctaaggt cctttgtatc ttgataattg aacacgcctg gaaccctgtg
   115741 tgaaaaagat agttcttcca agaagtagac acttcttgat tggaattcct attttcactt
   115801 tgtgttctta cggactttgt atcttagaca ggagtagaga tgagtattcg agtaattatt
   115861 gccggtttta agggaaagat gggccaggct gcttgtcaga tggtattgac tgatccagac
   115921 ttggacttgg tagcagtttt ggatcctttt gagtctgagt cagaatggca gggtattcct
   115981 gttttcaagg ataaggctga tttagctggt tttgaagcgg atgtctgggt agattttact
   116041 actccagctg ttgcctacga aaatacacgt tttgctcttg aaaatggctt tgctccagta
   116101 gttggaacga ctggtttcac gagtgaagaa attgcagagc taaaagaatt ttctcgtgcc
   116161 caagacttgg gtggcctgat tgcccctaac tttgccttgg gtgctgtctt actcatgcaa
   116221 tttgcgacgc aggctgccaa atatttccca aatgtggaga ttattgagct ccatcatgac
   116281 aagaaaaagg atgctccgag tggaacagcc attaaaacag ctgagttgat ggcagaggtt
   116341 cgagagtcca ttcagcaagg cgcagcagat gaggaagagc tgattgctgg tgctcgtggt
   116401 gctgactttg atggtatgca catccactca gttcgtttgc caggtttggt agcccatcag
   116461 gaagtcatct ttggcaatca gggagaaggg ttgaccctcc gtcatgactc ctatgatcgc
   116521 atctccttca tgacaggagt caatttggga attaaagaag ttgtcaagcg tcatgagctt
   116581 gtctatggat tagaacactt attatgagat taacgcaaat gccttctgaa tttcagaagg
   116641 ctttaccagt attagaaaaa attaaagaag caggctttga ggcttatttt gttgggggct
   116701 ctgttcgaga tgcccttctc cataacccta tccacgatgt ggatattgcg acgtcttctt
   116761 atccagaaga gaccaagcag atttttccgc gaacagccga tatcggaatc gagcatggaa
   116821 ccgtcttggt cttagatggg gatgaggagt atgaggtaac aacctttcgg acagaggatg
   116881 tctatgtgga ctatcgcaga cccagtgcgg tttcctttgt gcgctcgcta gaagaagacc
   116941 tcaaacgccg tgatttcaca gtcaacgcct ttgccttgga tgagacagga gaaatcgttg
   117001 acttgttcca tggtttagaa gatttggaaa agcaagtctt gcgagcagtt ggagtggcta
   117061 gtgagcgttt caacgaagat gctttacgga ttatgcgtgg tttccgtttt caggctagtc
   117121 ttggttttgc acttgaacca gaaacattta aagctatgaa gaccttgacg ccgcttttgg
   117181 agaacatttc tgtagagcgt accttcgtcg agtttgataa actcttgctg gctccatttt
   117241 ggagaagggg cttggcttcc atgattgaga gtcaagctta tgactatctc cctgatatgg
   117301 catctagcca ggacaagctc aacagactgt ttgatttgga gactgatttt acttttgaat
   117361 cctctgaaca agcctgggcg gctttactat gggctttgga gattgaaaat gcgcagtcat
   117421 ttttgaaatc ttggaagacc tcacgccagt ttgccaagca agttcaggat ttgctgatta
   117481 ttttggctct gcgtgaaaat ggagaattga gcaagcgaga ttgttatcgc tttgacatag
   117541 atttgctttt acaggctgaa aatcttcgtc aagctcaagg aaaagaagtc aacccacaag
   117601 ccatcacaga aaaataccaa agcttgacta tccatgacaa gaaagagatt cagattaatg
   117661 gcggtatttt gatcaaggaa tatggctatc agccaggccc agacttggga gagattttaa
   117721 cagagattga gtttgccatt gtcgatggag aattggagaa taatcgtgaa gccatccatg
   117781 cttacctgag ggagaaaaaa tgagtgattt tatcgttgaa aaactaagta aatccgttgg
   117841 tgacaagacc gtttttaggg atatttcctt tattatccat gacttagaca gaattggttt
   117901 aatcggtgtc aatgggactg gcaagaccac ccttttggac gtcctttctg gtgtttctgg
   117961 atttgatggg gatgtcagtc ctttttcagc taaaaatgat taccagattg gttacttgac
   118021 tcaggatcct gattttgatg atagaaagac agttttggat acggttctat ctagtgaact
   118081 caaggaaatc cagctcattc gtgagtatga attgattatg ctcgactata gtgaggacaa
   118141 gcaggcgcgt ttggaacgtg tcatggcaga gatggactct ctccaagctt gggaaatcga
   118201 aagtcaggtc aagaccgttc ttagcaaatt gggcattcaa gacttatcta ctcctgttgg
   118261 ggaattgtca ggtggtctga gaagacgggt acagttggca caagtcttac ttggcaacca
   118321 cgacctcttg cttttggatg agccgaccaa ccatctggat attgcgatta ttgagtggct
   118381 gaccctcttt ttgaaaaatt ctaagaagac cgtccttttt atcactcacg atcgttattt
   118441 cttagacgct ttgtcaacac ggattttcga gttggatcgt gcaggcttga ccgagtacca
   118501 gggaaattac caggactatg ttcgcctaaa ggcggaacag gatgagcgcg acgcggctct
   118561 tcttcacaaa aaagaacaac tctacaaaca agaattggcc tggatgcgca gacaaccgca
   118621 ggcgcgtgcg accaagcagc aggcccgtat caatcgattc catgatctga aaaaggaagt
   118681 ttcaggcagt agtgctgaga cagacttgac catgaacttt gaaaccagtc ggattgggaa
   118741 gaaagtcatc gagtttcagg ctgtttcctt tgcctatgaa aacaagccta ttttgcaaga
   118801 ttttaatctc ttggtgcagg ccaaagaccg tatcggaatc gttggggaca atggtgttgg
   118861 aaaatcaacc ctgctcaact tgattgcagg aagtcttgag ccaactaaag gacaagttgt
   118921 gattggggaa actgttcgca tcgcctattt ctctcagcaa attgagggtt tggatgaaag
   118981 caagagagtt atcaattacc tgcaggaagt ggcagaagag gtcaagacca gtggcggttc
   119041 tacgacttcg attgcagagt tgctggagca gttccttttc ccacgttcga cgcatggaac
   119101 cttgattgag aaattgtcag ggggtgagaa aaaacgtctt tatctcctca aactgctttt
   119161 ggaaaaacca aatgttcttc ttttagacga gccaaccaat gacctagata ttgcaacttt
   119221 gacagtctta gagaatttct tgcaaggttt tgcaggtccc gttttaacag tcagtcacga
   119281 ccgctatttc ttggataagg tagcgaccaa gattctcgct tttgaggatg gcaagattcg
   119341 tcctttcttt ggtcattaca ccgactatct tgatgaaaaa gcttttgaaa cagatatggc
   119401 caatcaagtg caaaaggtcg aaaaggaaaa agtggtcaag gttcgagaag acaagaaacg
   119461 catgacctac caagaaaagc aggagtgggc aagtattgaa ggtgatattg aaaccttgga
   119521 aaaacgtatc gctgctattg aagaggaaat gcaggctaac ggctctgact ttggtaagct
   119581 ggctactctc caaaaagaat tggatgagaa aaatgaagca ctccttgaaa aatacgaacg
   119641 ctatgagtat ctcagtgaat ttgatagtta agactattcg aaaatcaaag tgcaaactat
   119701 gtcggcttca cattgccgac tcaagtacag cctgtgaccg gcttcctaat ttgcactttg
   119761 atttttattg agtataaacg aatagaaaaa tcccgtctca tgaaaggatt tctctattct
   119821 tttttggttt cttgatgaaa gatattttgc caggtttcgt ggcgacgcca gatactggta
   119881 tggatgatac catctaactc atagcagata agtttggttt tttgactgat ggaagtaatt
   119941 tgaatgtcct tgatagcaga atttaactct tttttggtct tataagcctc tttatccatc
   120001 tgctctccat cttggcgaat atagacaaaa tcatcagtca agagttcttc tagttggttt
   120061 ccttggtcga tcaattgttc acgcataagc aattttttat agacattgtc taaaatttca
   120121 tcctcaggga taggtgctgg ttcgatatgg acatcggtat caaagacgcc aaaacgctcc
   120181 tccagcatag actcgacctg atccgcgatt tcatggcttt caaaaacaga caagtcagga
   120241 ttcatctcta gtgtaatatc caggtagatg ttgctaccgt aggtgcgacc tctttgcgat
   120301 ttgaccttgc tgattttggg aatttccatg atagcctttt ggtagtcctc gagcaggcgg
   120361 tcgtcaaagc catctgaaag actaaaggaa gactcgatga agatatcata ggcagtcttc
   120421 aagataaaga aagtgatgat gatagcaacc agtttatcca caatcggata attgaaacta
   120481 ctagctagga tggcaatggc ggttccaagt gaggtaacag cgtcagaaag attgtcctta
   120541 gcagctgcct tcagcgcctt ggagttggat ttcttactga ggcgagtatt gtagagatag
   120601 accacaaaca taatcgctgc agaaatgatt cctagagttg caccaagagg atcaatgacc
   120661 gtttcttccc gactgagaat cttttgaatg gtatctctta gaacatcgaa accgacatag
   120721 aacatgatga tagaagtgat caagcttgcc aaatcttcaa tcttccaatg accaaaacgg
   120781 tggtcacggt ctgcaggctg gcgcgccatc cgaatcccga ttaagagggc cacatttcca
   120841 atgatgtccg atacgttatt aaaaccatcg gccaccaaac tggatgaatg aaggagatga
   120901 ccagttgcta atttggctgc agacaagatc aaataggtcg aaatactgat aatggctcca
   120961 cgctcagcta acttgagatt tgagatagat tgcttcattc aacttccttt ctagtcacat
   121021 agcattctac cattatactg gttttcaagg aaaaattcaa ataaggcagt ttttactctt
   121081 tgaaaactcc ccaaaatttg gtataatggt actactcaag ggagtagctg gcagaaacct
   121141 gtgatagtgt cgtcattccg aattttatgc tgaaaagtat gctttccggc cctatcttaa
   121201 acagcgagac ttgttatgat taacaggtct ctttttgttt gtcgtgaaaa gatatgacag
   121261 aaagagagtc tgttttgcac acaatgtcaa ggaggagaca catgtcaaaa gaacaaaaac
   121321 gccaagcgtt ttatactcag agccctgaag aggtcttgca ggctgtggat gcgaccgagc
   121381 aaggtttgtc atcaagtgag gcggaaaagc gccttgccga atttgggcac aatgaactcg
   121441 aagaaggcga gaaacgatca atcttggtca aattcatcga gcaatttaag gatttgatga
   121501 ttatcatcct agttgcggca gcaatcttgt cagtcgtgac ttctggtggg gaagatatcg
   121561 cagatgccat tatcatccta gctgtggtta tcatcaacgc tgcctttggt gtttaccaag
   121621 aaggaaaagc tgaagaagct atcgaagccc tcaaatccat gtctagtcca gttgcccgcg
   121681 ttcttcgtga tggacacatg gcagagattg actctaaaga attggtacca ggcgatatcg
   121741 ttgcccttga agcaggtgac gtggtaccag cggacctacg tttgctagaa gccaactctc
   121801 ttaaaattga agaagcagcc ttgacaggtg aatctgtacc agtcgaaaaa gacttgtcag
   121861 tcgatcttgc gacagatgct ggtattggtg accgtgtcaa catggccttc caaaactcaa
   121921 acgtaaccta tggtcgtggg atgggtgttg ttgtcaatac aggtatgtat actgaagttg
   121981 gtcatattgc tggtatgctt caagatgcgg atgagactga tacaccactc aaacaaaact
   122041 tgaacaacct ttctaaggtc ttgacctatg ctatcttggt cattgccctt gttacttttg
   122101 tagtgggtgt cttcattcaa gggaaaaatc cacttggtga gttgttgact tctgttgccc
   122161 ttgccgttgc agccattcca gaaggacttc ctgctatcgt taccatcgtt ctttctcttg
   122221 gtactcaagt tttggccaaa cgacattcca tcgttcgtaa gttgccagca gttgaaacac
   122281 ttggttcaac tgaaatcatc gcttctgata agactggtac gctgactatg aacaagatga
   122341 cagtcgaaaa agtcttctac gatgcggttc tacatgactc agctgatgat attgaactag
   122401 gtcttgaaat gccactactt cgttcagttg tcttggccaa tgatacgaaa atcgatgtgg
   122461 aaggtaactt gattggtgac ccaaccgaaa cagcctttat ccaatatgcc ttggacaagg
   122521 gctatgatgt caaaggtttc ttagagaaat atcctcgtgt agctgaattg ccatttgact
   122581 ctgaccgtaa gctcatgtca acagttcacc cattgccaga tggtcgtttc cttgtagcag
   122641 tcaagggtgc gccagaccaa ctcttaaaac gttgtcttct tcgtgataag gctggggata
   122701 ttgctccgat tgatgagaag gttacaaatc tcattcatac aaacaattct gaaatggctc
   122761 atcaagcctt gcgtgtcctt gcaggtgctt ataagattat cgatagtatt ccagaaaatc
   122821 tcacttctga agagcttgaa aatgatttaa tttttactgg tttgattggg atgattgacc
   122881 ctgaacgtcc tgaagccgct gaggctgttc gtgtggctaa ggaagcggga atccgtccaa
   122941 ttatgattac aggtgaccac caagacacag cggaagccat tgccaaacgt ttgggaatca
   123001 ttgacgcaaa cgatacagaa ggtcacgttt taactggtgc tgaactcaat gaactgtcag
   123061 atgaagaatt tgaaaaagtc gttggtcaat actctgttta tgcccgtgtg tctccagaac
   123121 acaaggttcg tatcgtcaag gcttggcaaa aacaaggtaa agtcgttgcc atgacaggtg
   123181 acggtgtcaa tgacgcgcca gctctgaaaa cagccgatat cggtatcggt atgggaatca
   123241 ctggtacaga ggtttctaag ggggcttctg acatgattct tgcagatgat aactttgcga
   123301 ctattatcgt cgcagtggaa gaaggacgta aggtcttctc aaacattcaa aagactattc
   123361 agtacctact ttctgctaat actgctgaag tattaaccat cttcctatca accttgtttg
   123421 gttgggatgt cttgcagccg gttcatcttt tgtggatcaa cttggtaacg gataccttcc
   123481 cagctatcgc tcttggtgtt gaacccgcgg agcctggtgt catgaatcat aaaccacgtg
   123541 gacgcaaggc aagcttcttc tcaggtggtg ttttgagttc tatcatttat caaggtgtac
   123601 tccaagcagc tcttgttatg agtgtttatg gccttgcgat tgcttaccca gttcatgtgg
   123661 gtgacaatca tgctattcat gcagatgccc taacgatggc ctttgcaacc cttggtttga
   123721 ttcagctctt ccatgcctac aatgtcaagt ctgtctacca atccatcttg acagttggcc
   123781 cattcaagtc taagaccttt aactggtcca tcttggtatc ctttatcctt ctcatggcaa
   123841 caatcgttgt agaaccgctt gaaggaatct tccacgtaac caaactagac ttgtcacaat
   123901 ggggaattgt tatggctgga agcttctcaa tgattatcat cgtcgaaatc gttaagttta
   123961 ttcaacgcaa actcggtttt gacaagaatg cgatttaagg gaggtttcgg atgtcagcat
   124021 atcaattacc gaccgtatgg caggatgaag ctagtaatca aggagctttt acggggctaa
   124081 acagacaaac agcaggtgcc cgtttcgaac aaaacttgcc aaaaggagaa caagcttttc
   124141 agctttattc actgggaaca ccaaatggtg tgaaggttac tatcttattg gaagaattac
   124201 tagaagctgg ttttaaggaa gcggcttacg acttgtataa gattgctatc atggatgggg
   124261 atcaattcgg atcagacttt gtgaagctca atccaaattc caagattcca gccttattgg
   124321 accagtcagg tactgaagat gtaagagtct ttgagtctgc tcatattctt ctttaccttg
   124381 ctgagaaatt tggagccttt ttaccaagta atcctgtgga aaaggtagaa gttttgaatt
   124441 ggctattctg gcaagcaggt gcagcacctt ttctaggtgg gggatttgga catttcttca
   124501 attatgctcc tgaaaaattg gaatatccta ttaaccgttt tacgatggaa gtgaaacgcc
   124561 agttggattt attggataag gaattggctc agaaacctta tattgcaggc aatgactata
   124621 cgattgcaga tattgctatc tggtcttggt atggacagtt agttcaagaa aatctttacc
   124681 aaggttctgc aaaattcttg gatgcctcaa gttatcaaaa tctagtaaaa tgggcagaaa
   124741 aaattgccaa tcgtccagct gttaagcgtg gcttggaagt aacttataca gaaattaaat
   124801 agcaaaaaag tcatcttcgg atggcttttt gctacagttg agggaaaggg tttgcagtta
   124861 tcggcttttg tgctataatt gctataatat agtaaaaagc aagaggagtg tgaggaagtg
   124921 gaaaagaaaa ttgtgaagga taacttattt ttatctcaag tgtctcagcc ggcaagtcag
   124981 gaggaccttt atcttgccag agatttgcag gatacactct tagcaaatcg tgatacctgt
   125041 gttggtctag ctgccaatat gattggggtg cagaagcgcg tgattatctt taatcttggc
   125101 ttggttcccg tggtcatgtt taacccagtg cttctgtcct ttgaaggatc ctatgaggca
   125161 gaagaaggct gtttgtcctt ggtaggtgtg agatcaacta agcgttatga aaccataagg
   125221 cttgcctatc gtgacagcaa gtggcaggaa cagaccatta ccttgacagg cttcccagct
   125281 cagatttgcc agcatgagct ggatcacttg gaaggacgaa tcatttagga ggaaagcaaa
   125341 tgaaacgaat agtctttgaa cttattttta tcgcaacgac ctggtatatc tttttaccgc
   125401 cccttaacct gaccagctgg gaatttctct tcttcctctg tgggcatttg ttagttgtgg
   125461 caatcttatt tggctttggc aaggggataa accttgtcaa aacggttcat gtgcgccacg
   125521 gtaaggcgga agctgcctta aatcttgagg gtttcaaaat caatcggtta gggaaaattc
   125581 tgttagcttc gattggagga attcttctct tggcagcttt ggtttccttg gtaacttcca
   125641 gcatgtttca ggctaaaaat tatgccaatg tagtcacggt tacggaaaaa gactttactg
   125701 aatttcctag gagtgacacc agtaaggttc ctatcctaga tagaagtact gctgaaaaaa
   125761 ttggagaccg ctacttgggt tccctaaccg ataaggtgtc gcaatacgta gcggcagata
   125821 cctataccca attgacaatt gatgggaaac cttatcgggt cacaccacta gaatatgcag
   125881 accctatcaa atggtttaac aatcaagcca agggaatcgg tgagtatatc aaggtggaca
   125941 tggtaactgg aaatgcggat ttggtggact tgaagacacc aatcaagtat tcagactcgg
   126001 agtattttaa ccgtgatgtc aaacgtcacc tgcgcttgaa gtacccgacc aaaatcttta
   126061 aaactccatc ttttgaggtg gacgatgagg gcaatccttt ctatgtagca acggtttacc
   126121 aaaagcaatt tggacttgct gttcctcgtc ctgcttcagt cattatcttg gatgctacaa
   126181 atggagaaac caaggaatac agcttatcag atgttccaga atgggtggac aggatctatc
   126241 cagcagagga aaccattgag caaattaact acaacggcaa gtacaaggac ggtttcttga
   126301 atgccatgat ttccaagaaa aacgtgaccc agactaccaa gggctataat tacttgtcta
   126361 tcggtaatga catctatctc tacacaggtg tgacgtcggc taatgcggat gagagtaatc
   126421 ttggtttcat ccttgaaaat atgcgaacag gagaaatcac taagtatagc ttggcttctg
   126481 cgacagaaga atcagcccgt gaatcagcag aaggtgctgt tcaggagaaa tcctacaaag
   126541 caaccttccc aatcctcatc aacctcaatg acaagcctct ctacatcatg ggcttgaagg
   126601 acaatgctgg cttggtcaaa gagtacgccc tggtagacgc agtcgagtac caaaatgtta
   126661 tcgttgctac tacagtggaa gagatgctca gcaagtatgc caataaaaac gaccttgaaa
   126721 ttgacaatgc aacgacagaa agcatcaatg gagtagtagc agacctcaaa tcagctgtta
   126781 tcaagggaga cactgtctac ttctttaaag ttgatggcaa gatatacaag gtcaaggctt
   126841 cagtatccga tgaccttcct taccttgaaa atggtaaaac cttcgaaggt caagtaggaa
   126901 aagacaatta tctcaagacc tttaaagtac aataatactc ttcgaaaatc tctagctcta
   126961 tctgcaacct caaaacagtg ttttgagcag cctgcggcta gtttcctagt ttgctttttg
   127021 attttcattg agtataaaaa aggtttattt aataaatata tgttataata aggtaaatta
   127081 agcctaatgg aggacaaaga aatgggtttt tatttgatgg ttgcttcaat gctactcgga
   127141 ctgctcgctt tgaagatagg tttttctcag ttcaaggaga aaaaagataa attcttatct
   127201 atcttaacaa gtttagctgg cacagccctt gttctcgtgg ctgtctggtt aggatggccc
   127261 aaataaatag aaaaacctcg gtcaaaccga ggtttttcaa atgaatttct tggttgtggc
   127321 taaaaaatat gctacactat caatatgaaa attttaatcc caacagcaaa agaaatgaac
   127381 acagacttgc caagtatcga ggcaattcct ttaaaaccag aaagtcagac cgtgcttgat
   127441 gccttggctc tctattctgc cagtcaattg gagagtttct acaaggtatc agctgagaaa
   127501 gcggcggaag aatttcaaaa tatccaagct ttgaaaaggc aaactgctca acactatcca
   127561 gccttgaaac tttttgatgg gcttatgtac cgcaacatta agagagataa gctgaccgag
   127621 gcggaacaag attatcttga aaatcatgtc ttcattacct cggctttgta cggtgttgtt
   127681 ccagccttgt cacccatggc tcctcaccgt ttggattttt tgatgaaatt aaaagtcgct
   127741 ggtaagactt tgaagagcca ttggaaggca gtctatgatg aagctctgaa gaaggaagaa
   127801 gtgattttct ctctcttgtc atcagagttt gagactgtat tttctaagga aatcagagca
   127861 aagatggtga ccttcaaatt catggaggat agaggcggtc agctgaagat tcactcaact
   127921 atctccaaga aagcgcgcgg ggcctttcta acagctttaa tagaaaatca agtacaaact
   127981 gtgggggaag cacgtcgctt gaactttgct ggatttgttt accgagaaga tttgtcacaa
   128041 ccacagggat tggtttttgt aaaggaagta tagaaatcag atattttgta tttggcaata
   128101 tgtatcatca gctgttttag tttataaatg agaaaaaaag cgaacaagct agtcttctga
   128161 gtgtcagaaa agtagtcttg ttcgctttta ttatgttata ctcttcgaaa atctcttcaa
   128221 gccacgtcag cgtcgcctta ccgtatatat gtcactgact tcgtcagttc tatctacaac
   128281 ctcaaagcag tgctttgagc agcttgcggc tagcttccta gtttgctttt tgatttttat
   128341 tgagtgttag ttacttgata gcttcgacca agtcttgagc ttgtttttca agtgagttta
   128401 ggactgtttc ttcaagaacc aattttccgt ctgcccaggc agagtcatta acacgtgcag
   128461 cagtgaaatc accaacgcct tgtgtacgga taaatggcaa gaggtctttg tagatagcga
   128521 aaagttgatc gtgccctgca ttggctacag atgatactgt gacaaacttg tcttgaaggg
   128581 cagaaacgcc acgtgtatca gacaagtcaa gggcacgaga tagccagtca agcaagtttt
   128641 tcactgtacc agggatagag aagttgtaga ctggagagaa aatccagata gcatccgcaa
   128701 cgagaactgc ttcacgagcg gcagctacag ctggatgtgt tgggacttcc aaatcttggc
   128761 tgaagagagg gagggctgaa taatcaaggt agctaacttc cgctttacta gcaagtgctt
   128821 tctcagcttc gagcgccatt tggtggttga aagaaccttg acgtagtgat ccgacgataa
   128881 ataatacttt tttagacatg atgtgtctcc tttttcttaa aatttcgaga actctctcgt
   128941 tgttataaaa tatattacaa caaaacaaaa gaacttgcaa gaaatttgct cagagtttat
   129001 ttgaaaattg taaaatttcg gaaactctag tcatttgtga ctgaaaaagt aagaactgtt
   129061 tcactttcaa aatcggtttt gtttgaaggg agaaatagaa ttggttgctc aaagcacagc
   129121 tttgaggttg cagataaagc tgacgtggtt tgaagagatt ttcgaagagt attcttatat
   129181 tcacttgtaa taaagcttaa tagatggtaa aatagacgag tgaaaaaaag acaaaacaaa
   129241 gcaaaaaata atctactgtg gcagtatggt ctagggatga cgattttgtt tgtggttatc
   129301 agtggttcct ttctgtatat ggtttctctt agcatgaaac cctatcaaac agctaaaagt
   129361 gaaggagaaa aattagctca gcagtatgca ggattagagc aggtcgatca ggttgattta
   129421 tacaatggct tggaatctta ttacagcgtt cttggtcgta ataaacagca agaagcgctt
   129481 gctgtcctga ttggtaaaga tgatcataag atttacgttt atcagctaaa tcagggtgtt
   129541 tcacaagaaa aagcagaaac ggtttctaag gaaaagggag ctggcgaaat tgacaagatt
   129601 atctttggtc gttatcaaga taagccaatc tgggaagtca agtcaggatc tgatttttat
   129661 ctagtagatt ttgaaacagg agcattggtc aacaaggagg gcctatggaa ttatccaacc
   129721 gtgttttaga aatggaagaa agtgtgactt tggctgctgg agcccgtgcc aaagcactga
   129781 aggctgaggg tagagatatt ttgtctctaa ccttgggtga gccagatttc actactccca
   129841 aaaatatcca agatgccgcc attgcatcga ttcgagatgg gcgtgcttct ttttatacag
   129901 taacctcagg tctgccagag cttaaggcgg cggtcaatag ctactttgag cgcttttacg
   129961 gctattctgt agcgtcaaat caagtgacag tcgctgcggg agccaaatat tctctctata
   130021 ccttctttat ggctgtggtc aatccaggtg atgaagtcat catcccaacc ccatactggg
   130081 ttagctatgg agatcaggtc aagatggcag aaggcgttcc cgtctttgtt tctgctaagg
   130141 aagacaatca ctttaaggtg accgtagagc agttagaagc agctcgcact gacaagacca
   130201 aggttttggt gctgaattcg ccatctaatc ccacaggtat gatttacacc cgtgaggaac
   130261 tcttggcaat tggaaactgg gctgtagaaa atgatattct catcctagca gatgatatct
   130321 atggccgctt ggtttataat ggtcatgagt tcacaccgat ttctagccta tcggaagcga
   130381 ttcgcaagca aacagtggtc atcaatggtg tgtctaaaac ctatgccatg actggttggc
   130441 ggattggtta tgccgttgga gaagcagaca ttatcgctgc catgtccaag attgcaggtc
   130501 aaacaacttc gaatccgtca gcagtagccc aatatgcagc agttgaggct ctatcaggtg
   130561 agcaagatac tgtagaaagc atgcgtcagg cctttgagga acgtcttaat accatctatc
   130621 ccctccttgc agaagtgcca ggatttgaag tggtcaaacc gcaaggggcc ttctatctct
   130681 tcccaaatgt caaaaaggcc atggagatga aaggctacac ggatgtgaca gactttacaa
   130741 ctgttatctt agaagaagcc gaagtggcct tggtaacagg agctggattt ggagcaccag
   130801 aaaatgtccg cctcagctat gcgacagacc tagacacgct taaagaagca gtcgaacgct
   130861 tgaaagcatt tatgggtagt gagaatgatt gatcattttg agattaaggt aaaggattta
   130921 caaatttcag aaggatttta taggagtttt ctcgctcctt tggactataa attggctttt
   130981 aagactagtt ctctaattag ttttctatcc ccgaacagcc ctcatcctgg tggtgatttt
   131041 tggctgactc agggaacaca agatcctgtt cattttgctt ttttagcaga aaataaggaa
   131101 gaagttcagg cttgttatga ggctggctta gaggcaggtg ggcgagacaa tggggctcct
   131161 ggttatcgaa gtgagcatcc gatttactat gctgctttta tgattgacct ggatgggaac
   131221 aatatagagg tggtttgcca taaagaataa aaaagaaaag gaaaaataat gacaaaacgt
   131281 gtaacgatta ttgacgtaaa agactatgtt ggtcaggaag tgacgattgg cgcttgggtt
   131341 gccaacaaat caggaaaagg gaaaatcgct ttcttacaat tgcgtgatgg aacagccttc
   131401 tttcaaggtg tggcttttaa accaaacttt gtcgaaaaat ttggtgaaga agtgggactt
   131461 gagaagtttg atgttatcaa acgcttgagc caagaaacgt ctgtttatgt gacaggtatt
   131521 gtcaaagagg acgaacgttc taaatttggc tatgagttgg acatcacaga catcgaagtg
   131581 atcggtgaat ctcaagacta cccaatcaca ccaaaagaac acggaacaga ctttttgatg
   131641 gataaccgtc acttgtggct acgctctcgt aagcaagtag ctgtgttgca aatccgtaac
   131701 gctattatct atgcaactta tgagttcttt gacaagaacg gttttatgaa gtttgacagc
   131761 ccaattcttt caggaaatgc ggcagaagat tctacagaac tctttgaaac tgactacttc
   131821 ggaacgccag cctacttgag ccaatcaggt caactttacc tagaagcagg ggctatggct
   131881 cttggtcgtg tctttgactt tggtccagtt ttccgtgctg aaaaatcaaa aacacgccgt
   131941 cacttgactg agttctggat gatggatgct gagtactcat acttgacaca tgatgagtcg
   132001 cttgacttgc aagaagctta tgtgaaagct cttctacaag gtgttcttga ccgcgcgcct
   132061 caagccttgg aaaccttgga acgtgataca gaactcttga aacgctacat tgcagagcca
   132121 ttcaaacgta tcacttacga tcaagccatt gacctcttgc aagagcatga aaatgatgaa
   132181 gatgctgact acgagcatct tgagcatggt gatgactttg ggtcaccaca cgaaacttgg
   132241 atttcaaacc actttggtgt gccaacattt gtcatgaact atccagcagc catcaaggcc
   132301 ttctacatga aaccagttcc tggaaatcca gagcgcgtgc tttgtgcaga cttgcttgct
   132361 ccagaaggct atggagaaat tatcggtggg tctatgcgtg aggaagatta cgatgccctt
   132421 gtcgctaaga tggatgaact tggcatggat cgtacagaat atgaattcta ccttgacctt
   132481 cgtaaatacg gtacagttcc acacggagga tttggtatcg gtatcgaacg tatggtaacc
   132541 ttcgcagcag gaacaaaaca tatccgtgaa gctattccat tcccacgtat gttgcaccgt
   132601 atcaaaccat aagaacagga aaacgcccat gtggcgtttt ttcgaattct agtgttttta
   132661 cttgcgtaaa aaaatttttt ctagtataat agtttattgt gagcgaacct cacttacccc
   132721 ttgcaaagtc ttggggtcat tagaccaaaa ggaggaacat atcaatggct aaatacgaaa
   132781 ttctttatat cattcgtcca aacattgaag aagaagctaa aaacgctttg gtagcacgtt
   132841 ttgactctat tttgactgac aacggtgcaa ctgttgttga atcaaaaact tgggaaaaac
   132901 gtcgtcttgc atacgaaatc caagatttcc gtgaaggact ttaccacatc gttaacgttg
   132961 aagcaaatga cgatgcagct cttaaagagt ttgaccgtct ttcaaaaatc aacgctgaca
   133021 ttcttcgtca catgatcgtc aaaattgacg cgtaagaagg taaactatga ttaacaatgt
   133081 tgtacttgta gggcgtatga cacgtgacgc tgagttgcgt tataccccat caaatgtagc
   133141 agttgcgact tttactcttg cagtaaaccg tacatttaag agtcaaaatg gtgaacgtga
   133201 ggctgatttt atcaatgtcg ttatgtggcg ccaacaggct gaaaatcttg ctaactgggc
   133261 taaaaaaggc tcacttatcg gggtgacagg tcgtatccag actcgtagtt acgataacca
   133321 gcaaggacaa cgtgtctacg tgacagaggt cgtggctgag aatttccaaa tgttggaaag
   133381 ccgtagtgtg cgtgagggcc acacaggtgg agcttactct gcaccaactg caaactattc
   133441 agcacctaca aattcagtac cagacttttc acgtaatgaa aatccatttg gagcaacaaa
   133501 cccattggat atttcagatg atgatttacc attctaatgg acaactaaac ttataaagga
   133561 gaaaaaacat ggctcaacaa cgtcgtggcg gattcaaacg ccgtaaaaaa gttgattaca
   133621 tcgcagcaaa caaaattgaa tatgttgatt acaaagatac tgagcttctt agccgtttcg
   133681 tttcagaacg tgggaaaatc cttcctcgtc gtgtaacagg aacttcagct aaaaaccaac
   133741 gtaaagtaac aacagctatc aaacgcgctc gcgtaatggc tttgatgcct ttcgtaaacg
   133801 aagattaaag aaaagacccg gttgggtctc tttttcatga gcttgaaaac aagaaagcga
   133861 attaagaccc caacgggtct tttttcacaa gctttgaaat gagagagcga gttaggctca
   133921 gtggctccct ttttacgagt ttgaaaacaa gagaacacat taaaagcacg atggagcttt
   133981 ttcataaata tgtctttttt ctcatccaag aaattaaaat aaaaatgata aactttttga
   134041 aaatagggga tttgcctact ttatgatata atggaaagag ttagattgaa agaggtagtg
   134101 agatggacgc gaaattaaga tacaaggcaa agaagatcaa gattgtcttt tttgatattg
   134161 atgatacatt gcggaattca aagacagggt ttattccaac tacaattccc actgttttta
   134221 aacagttgcg tgaaaaagga attttaacag gaatcgcctc tggacgtggc atttttggtg
   134281 ttgttccaga gattcgtgat ctcaagcctg acttttttgt aactttgaat ggagcttata
   134341 tcgaagataa aaaaggtcag gtcatttatc agcatcagat tgaaaagtca gatgttgagg
   134401 agtatatctc ttgggctaag caagaaggaa ttgaatatgg cttggttggg agtcatgatg
   134461 ccaagttgtc gactcgcacc gatatgatga gtgaagctat caatccaatt tatcccgact
   134521 tagatgtaga tcccgatttc catgaaaaag aagatatcta tcagatgtgg acttttgaag
   134581 ataagggaga tgacttgcac ttgcctgaca gtctctcaga caaacttcgc atggttcgtt
   134641 ggcatcaaca ttcgtctgat attgtgccga tttcaggctc caaagcgacg ggggtggaaa
   134701 aggttgtgga acaccttggc ttgaaaccag agaaggtcat ggtttttgga gatggtctca
   134761 acgacttgga actctttgat tatgctggaa tcagcgttgc catgggaatt tctcatgata
   134821 aaatcaaaga aaaagcagat tatattacaa aaacattaga agaagatggc atttttgatg
   134881 ccttagaagt atttggtatg gtagaaaaag aattgcattt tccacaagta gacattgaaa
   134941 cagtagaagg tcctcttgcg actattaaga ccaatcacgg agacttacgt atcaagcttt
   135001 tccctgaaca tgctcctaaa acagtggcta actttgtatc tctttcaaaa gatggctact
   135061 atgatggtgt cattttccac cgtattatca aggactttat gatccaaggt ggagacccaa
   135121 ctggaactgg tatgggtggc gagtcaatct acggcgaatc ttttgaggat gaattctcag
   135181 aagagcttta caatatccgt ggtgctcttt ccatggcaaa tgctggtcca aataccaacg
   135241 gcagccagtt ctttatcgtg caaaaccaac acctacctta ttcgaagaaa gaaattactc
   135301 gtggtggttg gccagaaccg attgcagaaa tctatgccaa tcaaggtggg acacctcacc
   135361 tagaccgccg tcacacggtt tttggtcagt tagctgatga agcatcttac gctgtcttgg
   135421 atgccattgc tgctgttgag acaggagcta tggacaagcc agttgaagat gttgtaattg
   135481 aaactattga aatcgaggac taagatgaaa atcggtgata agctaaaggg gcgtattaca
   135541 gggattcagc cctacggtgc ctttgttgag ttagagacgg gtgatacggg gctgattcac
   135601 atttcagaaa ttcggacagg atttattgaa aatattcatg aaaccttgaa agtcgatgaa
   135661 gaggttcaag ttcaggtagt ggatttagat gaatttacgg ggaaagccag tctttctatc
   135721 cgcactttgg aggaagaaaa gtaccagttt cctagacgga gacgcttttc aagcgaccgc
   135781 tttaactacg gttttgctcc ctttcgacga atgctaccaa tctggactgg agaagccctg
   135841 caccatttaa aaaagaagaa gtagtttaga gttttatatt ttttgtaatg ttaatatgaa
   135901 tttgctataa taggaccatg gaagaagaac aattattaaa atcaggagag cgcattaacc
   135961 agctcttttc gacagatatc aaaatcattc aaaatagaga ggtttttagc tattcggtgg
   136021 atagtgttct cttatcacga tttccacgtt ttcctaagaa ggggttgatt gtggatttct
   136081 gtgctgggaa tggagcagtg gggctttttg ctagcactcg tactcaagca cagatattgt
   136141 ctgttgagat tcaggagcgt ttggcggata tggctgaacg ctctgtccgt ttgaatggat
   136201 tagaggagca aatgcaggtc atctgcgatg atttgaaaaa tatgcctgct cacattcagg
   136261 ggagtaaggt ggatatgatt ttgtgtaatc caccctattt caaggtgaat ccttattcta
   136321 atctgaacga gagtgaacat tatctcttgg ctcgacacga aatcacgact aatttggaag
   136381 aaatctgtcg tagtgcccag agtattctca agtctaatgg gcgtttggcc atggttcatc
   136441 gtcctgatcg acttctggat attttggata cgttaaaacg acataatcta gcccctaagc
   136501 gcctgcagtt tgtttatcca aaaagagaaa aggaagccaa tatgcttttg attgaggcga
   136561 tcaaggatgg ctcaacaagt ggctttaagg tcttacctcc tttgattgtc cacaatgatg
   136621 atggctctta tacgcccgaa atcgaagaga tttattatgg atcataaggc ttatatgtac
   136681 gttctggagt gtcgtgatgg atcctactat ataggctata cgactgatat gagaagacgc
   136741 ctcgctatcc acaatagtgg gaagggagcc aaatatacac gagcacgctt gccagtcaaa
   136801 cttatctatg ctcaaggttt tgccagtaag gaagaagcca tgtcggctga agctcttctc
   136861 aagcgtaaga agaggccaca gaaggaagaa tttttatctg aaaatcaaga tagaaattta
   136921 ctcagttatt ttgaagaatc gtggggagtc ctttgactcc tcttaccttt gtcaaaaagc
   136981 gaaaaaaatg ctacaataaa gaaaataaac aaaatgaggt attatcatgt ccaagattct
   137041 agtatttggt caccaaaatc cagactcaga tgccatcgga tcatctgtag cttttgccta
   137101 ccttgcaaaa gaagcttacg gtttggatac ggaagctgtt gcccttggaa ctccaaatga
   137161 agaaacagcc tttgtcttga actattttgg tgtggaagca ccacgtgtta tcacttctgc
   137221 caaagcagag ggggcagagc aagttatctt gactgaccac aatgaattcc aacaatctgt
   137281 atcagatatc gctgaagtag aagtttacgg tgttgtagac caccaccgtg tggctaactt
   137341 tgaaactgca agcccacttt acatgcgttt ggagccagtt ggatcagcgt cttcaatcgt
   137401 ttaccgtatg ttcaaagaac atggtgtagc tgtgcctaaa gagattgcag gtttgatgct
   137461 ttcaggtttg atttcagata cccttctttt gaaatcacca acaacacacc caacagataa
   137521 aatcattgct cctgaattgg ctgaattggc tggtgtgaac ttggaagaat atggtttggc
   137581 aatgttgaaa gctggtacca acttggctag caaatctgct gaagaattga ttgatatcga
   137641 tgctaagact tttgaactca acggaaataa tgtccgtgtt gcccaagtga acacagttga
   137701 catcgctgaa gttttggaac gccaagcaga aattgaagct gcaatgcaag ctgccaacga
   137761 atcaaacggc tactctgact ttgtcttgat gattacagat atcgtcaact caaactcaga
   137821 aatcttggct cttggtgcca atatggacaa ggtcgaagcg gctttcaact tcaaacttga
   137881 aaacaatcat gccttccttg ctggtgccgt ttcacgtaag aaacaagtgg tacctcaatt
   137941 gactgaaagc tttaatgcgt aagattttgg gtgtcagctc aaaatcggaa agtctagttt
   138001 gccttatatc gaaaggagtt tcggctcctt ttttctagga gtgaagtatg ttagaaaatg
   138061 gcgatttgat ttttgtgaga gatgggtcag acatgggaca ggccatccag acttccacag
   138121 gtaactatag ccatgttgcc atttatttgg atgggatgat ttatcatgct agtggacagg
   138181 ctggtgttgt ctgtcaagaa ccggcagact tctttgagtc caatcattta tacgacctct
   138241 atgtttaccc agaaatggat atccagtcgg tgaaggaaag agcttgcaaa catcttggag
   138301 caccctacaa tgcttctttc tatccagatg cacctggttt ctactgctcc cagtatatag
   138361 cagaaatcct acctattttt gaaactattc ctatgaaatt tggagatggg gagcaggaga
   138421 ttagtgattt ttggagggag tattacatag aactaggtct gcctgttcct ctgaaccaag
   138481 ctggtaccaa tcctagtcag ttggcagcat cgcctctgtt acaatgtaaa gaaaggaatc
   138541 ttcatgattc agatttttaa tccatctcgt ttgacgagac agccattttt ggagaattga
   138601 tccgctatct ggaccagtat gaggatgtga ttctacggga aattaaggct caatttccag
   138661 atgttgcagt tgataaactc atggaagagt atataaaggc aggcttgatt ctacgtgaaa
   138721 ataagcgcta ttacctcaat tttcctacgc ttgaatcact tgatagtctt gaactggatc
   138781 aagagatttt tgtcagagaa gctagtccgg tctatcaagc cttgttggag cagagttttg
   138841 agacggaatt gcgcaatcaa atcaatgcag ctattttagt tgaaaagacg gactttgcgc
   138901 gcattaaaat gactctgtcc aattattttt acaaggtcaa acagcagtat cctttgacag
   138961 aaaaacagca ggagctctat gacattttag gagatgttaa tcctgagtat gcactcaagt
   139021 atatgacggc ttttttgttg aaatttctca aaaaagacca gcttatgcag aaatgccgtg
   139081 atatctttgt ggacagtttg gttgtcttag gctatattgt gcaaaatgaa gatggaaagt
   139141 atgagttggc tatcgatttt gataaggaga gattaacttt ctacttagcg tgatttcttg
   139201 tttctgagta cattgtttga ctttccttag tattcggtat aaactatatg taaccggtaa
   139261 cacatatcgg aataaactaa aggagacaat catatgtcac ttgaaaacaa attggaacaa
   139321 gcaacaggcg ctgtcaaaga aggttttggt aaagttactg gagacagcaa gacagaactt
   139381 gaaggagctg ttgaaaaaac agttgctaag gcaaaagacg ttgtagaaga cgcaaaaggt
   139441 gctgtagaag gtgccgttga aggtttgaaa aacgttttta ctaaagaata ggaaaaaatc
   139501 aagggtttca ttttcccttg attttttcta ttcttataaa taattttctg cgacggctgt
   139561 atctcctggg taggattctt tcttgccctg gatgatttgg taacaatcgg ctcccttacc
   139621 cgcaataata actgcatcta attcgtgatt tgtgatagcc attgccgcct tgatggcttc
   139681 ttggcgatcc gcaatcttct caacaggatg attgatgtag ctactaattt catctgcaat
   139741 ggccattggg tcttcatagt tagggtcatc agcagtcaga aagacttgaa tctcagggtg
   139801 ttgattgagg aggaggccaa agtccttacg acgactttct cccttgtttc ctgttgatcc
   139861 cagaaccaga gcaatctttc cggtttgatg agtttcaacc acattgatga gttttttcag
   139921 actatcccca ttgtgggcat agtcgatgaa gaccttggct ccatttttct gagtgaggac
   139981 ttccatacga ccaggaacgc gggttgcagc gatgcctttt ttgatgtcct caagacttgc
   140041 tccgagacgg agacaagcaa gtccagcagc aactgcattt tcttggttga agttgccaat
   140101 gagttggata tcataatctc cagcgagttt acccgtagct gaaaagctaa aggctttgga
   140161 attctcgatt tggttatcaa attggctacc atagaaatca tggtcttgat cttcaacctg
   140221 ttctttcaag actgagaagt ggtccatgtc actgttaatg atgactgctc ggctattttc
   140281 catcaagaga cgcttgtggt agaaatagtc ttcaaagcta gggtgttcaa tcgggccgat
   140341 atggtctggg ctgatattga ggaaaactcc cacatcaaag gttagaccat agacacgtct
   140401 gaccagatag gattgactgg agacttccat gatgaggtgg gtacggtcat tttgcacagc
   140461 ctgattcatc atgtcaaaga ggtcaatact ctcaggggtt gtcaacgctg acttaaagaa
   140521 agtctcgcca tcaagagttg tgttcatggt cgacaacata gcaggtcgat gcccttgaga
   140581 taagatgtta taggcgaaat aggctgctgt tgtcttaccc ttagtaccag taaaggcaag
   140641 gagtttgagt ttttcctgtg gattaccata gaactccatg gcaatcaaac tcatggcttt
   140701 ctttatatcg ttcacaatga tgacagggat accgacttcg tagtcctttt cagctacata
   140761 ccaagctaag ccttgtgtta tagcagaaag aaggtattct tttttaaagg cagcgccttt
   140821 tgcaaaaaaa agagtgtctt ctgttacttt tcggctatcg tagctgatgc tatcaaaaac
   140881 aactttgctg tagttgtagt ggtaatgacc ttggtcaata atttcgcgaa aaaggccatc
   140941 tttctttaaa atatctaata cagtttcaat ttttatcata ctttctattg taaaccgaaa
   141001 gtcgcaaatt tacaagtaac aaggaaaagt ttataatgga agataaggag tttttcctag
   141061 ttatcaaaat tgaatgagga atctatgtcg cacgaaaaca atcaccagca ggcccagatg
   141121 ttacggggga ctgcttggct aacggctagt aactttatca gtcgcctact cggggctgtt
   141181 tacattatcc cttggtacat ctggatgggg gcttatgcag ctaaggcaaa tggtctcttt
   141241 accatgggtt acaatatcta tgcttggttc ttgttggttt caacagcggg gattccagtt
   141301 gcggtggcca agcaagttgc caagtataat accatgcgag aagaagagga tagctttgcc
   141361 ctgattcgga gcttcttagg ctttatgaca ggactaggcc tggtttttgc tttagtcttg
   141421 tatgtctttg ctccttggct agcagacttg tctggcgtgg gcaaagactt gatcccaatc
   141481 atgcaaagct tggcttgggg agtcttgatt ttcccgtcta tgagtgttat ccgaggattt
   141541 ttccaaggga tgaataacct caaaccttat gccatgagcc aaattgctga gcaggtcatt
   141601 cgtgttatct ggatgctcct agcaaccttt atcattatga agctcggttc aggagattat
   141661 ctagcagccg ttacccaatc aacctttgct gcctttgtcg gtatggtagc cagttttgca
   141721 gtcttgattt atttccttgc ccaagaaggt tcactcaaaa gagtctttga aacaggagat
   141781 aagattaaca gtaagcgtct cttggttgat accattaagg aagccattcc ttttatcctg
   141841 acagggtctg ccatccagct cttccagatt ttggatcagc tgacctttat caatagtatg
   141901 agctggttta ccaactacag caatgaggac ttggttgtca tgttttctta tttctcagcc
   141961 aatcctaata aaatcacgat gattttgatt tctgtagggg tttcgattgg gagtgttggt
   142021 ttgccacttt tgacggaaaa ctatgtcaag ggggacttga aagcagcttc tcgtctggtt
   142081 caggacagtc tcaccctact ctttatgttc ttgctaccag caacggttgg agtggttatg
   142141 gtaggagaac ctctatatac agtcttctat ggtaagccag atagtttggc tctgggctta
   142201 tttgtctttg cagttttgca gtctattatt ttaggcttgt acatggtctt gtctccaatg
   142261 cttcaggcca tgttccgcaa ccgcaaggcc gttctctatt ttatctatgg ttctattgcc
   142321 aagctagtct tgcaactacc taccatcgcc ctcttccaca gttatggtcc tttgatttca
   142381 acaaccattg ctctcatcat tcctaacgtc ttgatgtatc gggatatttg taaagtaact
   142441 ggtgtcaagc gcaaggtgat tttgaagcga accattttaa tcagtttgct gaccctagtc
   142501 atgtttctgt taataggaac catccagtgg ctgttaggat ttttcttcca accaagtgga
   142561 cgtttgtgga gcttctttta tgtagctctt gtcggtgcca tggggggtgg actttatatg
   142621 gttatgagtc tgcgtaccta tttattagat aaggtaatag gaaaagccca agcagatcgc
   142681 ctgcgagcaa aatttaagct ttcgtaaggt agcatttata aataaaagga ataagttgaa
   142741 caatctttta ggagaacttg aaacttattc cttttttagc gtcaaaatag ctaaaattat
   142801 ctttcaaaaa tagaaaatga ggtttttttg attttttgga aaaaacaatt gactaaacaa
   142861 accaagagtt gtataataaa acaaatattt aaagcaggag gttctggaaa tgaaaaagtc
   142921 taagagcaaa tatctaacct tggcaggtct tgtcctgggt acaggagttt tattgagcgc
   142981 gtgtggaaat tctagcactg catcaaaaac ctataactat gtttattcaa gtgatccatc
   143041 tagtttgaac tatctagcag aaaaccgcgc agcaacatcc gatattgttg caaatttggt
   143101 agacgggtta ttagaaaatg accaatatgg gaatattatt ccatcattag cagaggattg
   143161 gactgtttct caggacggtt tgacctatac ctacaaactt cgtaaggatg ccaagtggtt
   143221 tacttctgag ggagaagaat atgcgcctgt aactgcccag gattttgtga caggtttgca
   143281 atatgcagct gataaaaaat cagaagcttt gtatctagtg caggactctg ttgctggttt
   143341 ggatgactat atcactggta aaacaagcga cttttcaact gtcggtgtca aggcacttga
   143401 tgaccaaacg gttcaatata ctttggttaa accagaactt tactggaatt caaaaacact
   143461 tgcaacgata ctttttcctg ttaatgcaga tttcctgaaa tcaaaagggg atgattttgg
   143521 gaaggcggat ccatctagta ttttgtacaa tggacctttc ttgatgaaag cacttgtctc
   143581 aaaatctgct attgaatata agaaaaaccc taattactgg gatgctaaga atgtctttgt
   143641 agacgatgtg aaattgacct actatgatgg tagcgaccaa gaatcactgg aacgtaattt
   143701 tacagctggt gcttatacta cggctcgtct ttttcctaac agctccagct atgaagggat
   143761 taaagaaaaa tacaaaaaca atatcatcta tagtatgcaa aattcaactt catatttctt
   143821 taattttaac ctagatagga agtcttacaa ttatacttct aaaacaagtg acattgaaaa
   143881 gaaatcgacc caggaagcag ttctcaataa aaacttccgt caggctatca attttgcttt
   143941 tgacagaaca tcttatgggg ctcagtctga agggaaagaa ggtgcaacaa agattttgcg
   144001 taacctagtg gttcctccaa actttgtcag tatcaaggga aaagactttg gtgaagttgt
   144061 agcctctaag atggtcaact atggtaagga atggcaaggt atcaactttg cggatggtca
   144121 agacccttac tacaatcctg agaaagccaa ggctaagttt gcggaagcta agaaagaact
   144181 cgaagcaaag ggtgttcaat tcccaatcca cttggataag actgtggaag taacagataa
   144241 agtaggcata caaggagtta gttctatcaa acaatcaatt gaatctgttt taggttctga
   144301 taatgtagtg attgacattc agcaattaac atcagatgag tttgacagtt caggctactt
   144361 tgctcaaaca gctgctcaga aagactatga tttatatcgt ggcggttggg gacctgatta
   144421 tcaagacccg tcaacctatc tcgatatttt taatactaat agtggaggag ttctacaaaa
   144481 tcttggacta gagcctggag aagccaatga caaggctaag gcagttggac tggatgtcta
   144541 tactcaaatg ttggaagaag ctaataaaga gcaagatcca gccaaacgtt atgagaaata
   144601 tgctgatatt caagcttggt tgattgatag ttctttagtt cttccaagtg tttcgcgtgg
   144661 gggaacacca tcattgagaa gaaccgtacc atttgctgct gcctatggtt taaccggtac
   144721 aaaaggggtt gaatcatata aatacctcaa agtacaagat aagattgtca caacagacga
   144781 atatgcaaaa gccagagaaa aatggttgaa agaaaaagaa gaatccaata aaaaagccca
   144841 agaagaattg gcaaaacatg tcaaataaaa tctaattgta gataagtttg tgtaagaagt
   144901 ctttgtgctt aaaaacgcat aatatcaggt atataaaatc ctagatgtta tgcgttttgt
   144961 tataggaaga tttattagat tttatcctca aattgagtta ttcccgactt tatccgttga
   145021 aatattataa ggagtattta tgaaattaaa attattaaga gtagatacta aggtgattat
   145081 ggggagtttc ttacttgttc tgtctagtct acttgctttg ttgcttcccc ttatcttaaa
   145141 gggtttaata gatgggagtt ctattgaaaa tataggttcc aaagtatttc aatcgttttt
   145201 gatttttatt ggtcaagcct tgttttcttc tattggttac tatctgttta gtcaatcggg
   145261 tgaaaaaaag atagcaaaaa tcaggaaaaa agtgatagag gggttgattt atgcagagaa
   145321 atccttcttt gataagagcc aaagtgggga gttgacttct gccattgtca atgacatgag
   145381 tgtcattcgt gagtttttaa ttacgacttt cccaaatatt attctgagtt tagttatggt
   145441 acttggttcc attgtagtct tatttagtct tgattggaat ctttctctac ttttattcat
   145501 cactcttcct tgtatgatgt ttattatctt gcccctttcc aatatcagtg aaaagtatag
   145561 tcgtcgttta caggaggaaa tttaacaggg caattgactg aaaagattca agaacatgaa
   145621 ttaattaaga ctaaccaagc agagaaaagt gtacaggatg ttttggataa ttgtattgaa
   145681 agggtacaaa acaattcact gaaatcagat agggttactt cttttgagac ctcgtttgct
   145741 ctcttattta tctttgcgac tatagttgtg atgctaacct atgggggtta tcgggtcagc
   145801 gcaggatata tatctgtggg aaccttggtt tcgtttttga tttacctctt tcaattactt
   145861 aatcctatta gtaatatagc taattttgta actgtttatt ctaggagcaa gggatcttca
   145921 gttgcactgg ataacttgct tgcagttcct aaagaaaaat ttgagggagg aaaatcggta
   145981 tcaggacaag ggttgaattt taaccatgtc tattttggtt atgatgaaaa tcgacctgtc
   146041 ttaaaggata ttacttgttc aattttcaag gggcaaaaat tgcttttgtt ggaccatctg
   146101 gatcaggaaa atcaacgatt gtgcgtttgt tagagcggtt ttataaaccg ctttcaggag
   146161 atattctaat ggagcaatca agtatatatg attttaactt aaaagaatgg agaagtaaaa
   146221 tcgcttgggt ttcacaaaat aatgcagtct tatctggcag tattcgtgac aatctttgtc
   146281 tcggtttgaa tcgcttagta actgatgatg aattgatgaa agtgctagac ttagtatcac
   146341 taggtgatga gattcgctcc atgaaagagg gactagatac tgaagttggt gaacgcggac
   146401 gattcttgtc aggggggcaa agccaaagac ttcaaatagc tagaacctac ttaaaagatg
   146461 ctgaaattct tatatttgat gaagctactg ctaatcttga tgcggattct gagtatgcga
   146521 ttatcagtag cctctattct gtattaaagg agaagacggt tgtgattata gcgcatagtt
   146581 tgtcaacggt aaaagatgtg gattgtattt tcttcttaga ggaggggaaa atcactggct
   146641 caggaactca taaggaacta ctggaaaatc atgagcgtta tgctcgtttt gtgcaggagc
   146701 aaatgataga gtgaagtgtc ttttgagatt caccatttta tagtctatta aagggagcag
   146761 gaaaaactcc ctttttatat agtttgaaac tataactagc tcttgaaaag aagaaaatga
   146821 gttgatgaaa ataagtggta caatagttac tatagatttg gaggtattgt atgagcaagg
   146881 aattacacat taacacaatt ttggcccagg cgggtattaa gtcagatgaa gcgacaggtg
   146941 cattggtgac accgcttcat ttttcaacga cctatcagca tccagagttt ggtcgatcta
   147001 ctgggtttga ctatacgcgc actaaaaatc caactcgtag taaggctgag gaagtcttgg
   147061 cggctattga gtcagcagac tatgccttag cgactagctc agggatgtca gctattgtac
   147121 tggcctttag cggctttcca gtaggaagta aggtcttggc agtgcgtgat ctttacggcg
   147181 gttcttttcg ctggtttaac caagtggagc aggaaggtcg tttccatttt acctatgcca
   147241 atacagaaga agagttgatt gccgagttag aaaaggatgt ggatgttctc tatatcgaaa
   147301 ccccaaccaa tcccttgatg ttggaatttg atatcgaaaa actagcaaaa ttggctcatg
   147361 ctaagggtgc caaagtggtg gtggacaata ccttctatag ccctatctac caacgtccga
   147421 ttgaagatgg agcagatatc gttctccatt cagcaaccaa gtatctagca ggccacaatg
   147481 atgtcttggc tggagtggtt gtgaccaata gtttagaact atacgagaag cttttttaca
   147541 atcttaatac aacaggggca gtcttgtctc catttgacag ctatcagttg cttcgtggtc
   147601 tcaagacctt gtctcttcgt atggagcgct caacagctaa cgcccaagaa gtggttgcct
   147661 ttttgaagga ttctccagca gttaaggaag ttctctacac tggtcgtgga ggcatgattt
   147721 cctttaaagt agccgatgaa acacgcattc ctcatatttt gaacagtctc aaggtcttct
   147781 cttttgcgga aagtttgggt ggagtggaaa gtcttattac ttatccaacg actcaaactc
   147841 atgctgatat tccagcagag gtacgccatt cttatggttt gacagatgac ctcttgcgtt
   147901 tgtctattgg gattgaggat gctagagatt tgattgcaga tttgcgccaa gccatagaag
   147961 gataagacaa agatgggaaa atatgatttt acaagcctgc ccaaccgttt agggcaccat
   148021 acctataaat ggaaagaaac agaaacggat agtgaagttc taccagcttg gatagcggat
   148081 atggactttg tggtcttgcc tgaaatccgc caagccgtgc aaacttacgc agaccaactg
   148141 gtttatggtt atacctatgc cagtgaagac ttaattaagg aagttcaaaa gtgggaagct
   148201 acacaatacg gttacaactt tgacaaagag gctcttgtct ttatcgaggg tgtggtacca
   148261 gccatctcaa cagctattca aacctttaca aaagaaggcg aggcggtttt aattaacacg
   148321 cctgtctacc caccctttgc tcgcagtgtc aagttgaata atcgtagatt gattactaat
   148381 tccttagtgg aaaaggatgg tctgtttgag attgactttg accaacttga aaaggatttg
   148441 gtggaagagg aggttaaact ctatattctt tgcaaccctc acaatcctgg tggacgtgtt
   148501 tgggaaaaag aagtgttgga gaagattggc caactctgcc aaaaacacgg tgttttgtta
   148561 gtttcggatg agattcacca agatttgacc ctctttggtc acaaacacca gtctttcaat
   148621 accatcaatc ctgccttcaa aaattttgct atcgtcttga gcagtgccac taaaacattt
   148681 aatattgctg gaacaaaaaa ttcctatgca gtcattgaaa atcctaagtt gagactagct
   148741 ttccagaaac gcctgttggc caataatcag catgaaattt caggcttggg ttatttggcg
   148801 acagaagctg cctatcgata cggtaaagat tggctagagg aactcaagca agtctttgaa
   148861 gaccacatca attatgtggt ggatctattt ggaaaagaga ctaaaatcaa ggtcatgaaa
   148921 ccgcaaggta cctacttgat ttggcttgac ttttcagctt atgacctgac tgatgaaaca
   148981 ttgcaagagt tgttgagaaa tgaagccaag gttatcctca accgtggttt ggattttgga
   149041 gaggaaggaa gtctccatgc ccgcatcaat atagctatgc ccaaatctct gttgcaagaa
   149101 gtctgtcagc ggattgtggc tacttttgcc aaacgttaaa aatccagcct tctaggagaa
   149161 aagtcttcct agaaggctat tttcataggc gaaaatatgg tataataaaa agataaggta
   149221 aaggtgaaaa tatggctaaa ttgattccgg ggaaaattcg tatcgaaggt gttgcccttt
   149281 atgaaactgg taaggttgat atcatcaagg aaaagaacaa tcggctctac gctcgcgttg
   149341 cagaagaaga actgcgctat agtttagagg atgatttggt tttttgtgcc tgtgattttt
   149401 ttcaaaagag gggttactgt gtgcatttgg cagcgctaga gcattttctg aaaaatgatg
   149461 agcgtggtca ggaaatcttg tggagtctgg aagaaggtca tgaagaaaaa gaggctgttg
   149521 aaaccaaggt gaccttgggt ggcaagtttt tggatcgaat tttatctcca aaatcagaat
   149581 gcgcctatga gttatcagct gtgggtcagg tggaagcagg aaccaatcat atcttgtgga
   149641 ctctgagaat cggccaaatc aatagccaaa aatactatgt cattcgggat attccacttt
   149701 ttttaaggat tgtcgagcag agaaagtcgt atatgattgg caagatttat gaggagtctc
   149761 tttcttggga agcctttgat gatgccagcc aagaactttt gactttcttg cacggactaa
   149821 cggaggaagg gctggtttca gacctctttt tccaaaacca aggtcggcac ctctttttcc
   149881 ctctgacctt ttttgagcag ggtgtgaatt tactgatggc cttgccccat tttcaatttg
   149941 accatcaagt ggatagctac caaaccctgc tttttcagga tatgcatgct gatgccaatc
   150001 tatttgcctt tacagtaaca gaatactcgg actattttga aatggaaatc agtgagagtc
   150061 ctagggtcaa tgtcttttat cagggagcag tacttttcca taaaggtcag gtttattttt
   150121 taacagacca gcagatgcgt cttctcaagg aaattaaagc gttacctgtg ggtcaacaag
   150181 gaaagaaata cctgcaattt gatagcagtg atcgagacaa attggcctcc tgtctgactc
   150241 tttttatcca gatgggcacc gtttcagctc cagaacgtct acaaatcaaa acttttgcgc
   150301 cctcttttta ctttgacagg gaagaagata atcggattcg tttagaaatt cagtttgatt
   150361 atggaaatag acaggtatct agccgacaag agctagaaga attaccattt tcaagtgacg
   150421 cggacttaga agaaagaatt ttccaagtct gtttggctgc gggctttgaa gccgattttc
   150481 aatcttggcg tcaggcctta aaagcggagt ctgtctatca tttttttcat gatatcattc
   150541 cagtctttga aaaactcggg catgttgacc tatcagataa actagaagag ctttatagcc
   150601 tagcgagtcc tcaggtgcag attgcctcca agggaggtct cttggaaatc cagtttgatt
   150661 ttcaagatat tgcccaggag gaaatcgacc aagccatgca ggccttggtt gccaatcagg
   150721 atttttatat tgattcgtct aatcaagttt actttttcga tgaagaaacc aagaaaattc
   150781 gccaaaatct acaggaactg gggcaatttg aattaaaaga tgggaccttg caggctcgga
   150841 aatccttggc ctacagttta gctcatctct ttgaagggcg agaccgtgtt tctttttcac
   150901 aagaattcca gaatctggcc caggatttga cacatccaga ggactttcct cgacaggcaa
   150961 ctcaggttca ggctgacttg cgagattatc aggaaaaggg aattggctgg ttgcagatgc
   151021 tccatcatta tggttttggt gggattttgg ctgatgatat gggacttggg aaaacccttc
   151081 agaccattgc ttttttgact agtcaagtga caaaagaaag tcgggttttg attctcgctc
   151141 cgtcaggttt gatttacaac tgggcagatg agtttcagaa atttgcccca cagttggatg
   151201 tggctgttgt tcatggtttg aaagcaagtc gtgaggagat tcttgccgag agccatcaaa
   151261 tctatgtgac tagctatgcc accttccgtc aggacagtga gttttatcag gggatggcct
   151321 ttgacttcct tttcttagat gaggctcagg tcatgaaaaa tgcccagacc aagattgccc
   151381 agaccttgag acaatttgtg gtgccgtcgg tctttgcctt gtcaggaact ccgattgaaa
   151441 accatctggg tgagttgtgg tctattttcc aaatcgtcat gcccggactt ttgccaagca
   151501 agaaagaatt tatgaaattg ccagcagagc gagtggctca gtttatcaag cctttcgtga
   151561 tgcgacgcaa gaaagaagaa gttctgactg aattgccaga cttgattgag gtggtttata
   151621 aaaatgaact ggaagaccag caaaaggcta tttaccttgc ccagttacaa cagatgcgag
   151681 accatctggc tcaagtgtca gaacaggaat ttcagcgaag tcgtgtggaa attttatctg
   151741 gtttgatgcg cttgcgtcaa atatgtgaca ctcctgccct gtttatggaa gattatcagg
   151801 gagccagcgg caaactagat agtctccgag atctactggt acaggtggca gacggcggac
   151861 accgtgtctt gattttctct cagttcaagg gaatgttgga aaaaattgaa caagaactgc
   151921 cagacttggg cctgacatcc tttaaaatta cgggtttaac cccagccaag gaaagacaag
   151981 acatgaccaa ggcctttaac caaggagaaa gagatgcctt tctgatttcc ctcaaggctg
   152041 gtggggtcgg tctgaacctg acaggtgcag atacagtgat cttggttgac ctttggtgga
   152101 atcctgcggt ggaagcgcaa gccattggcc gtgcccatcg gatgggtcag gaagaaacgg
   152161 ttgaggtcta tcgcttggtg accaagggaa ccattgaaga aaaaattcag gaactccaag
   152221 aacaaaagaa acatctggtg tcacaagtat tggatggcac agagtcacgt ggtagtctga
   152281 ccctagcaga aattagagaa attttgggaa tttctgaagc cagcacttga aaaatcaaga
   152341 caatacgcta taatgaagtg ttgaaaggaa atagaaaatg aaacaagaac gatttccatt
   152401 ggtgtcagat gacgaggtca tgttgactga aatgccagtc atgaatctct atgatgagtc
   152461 tgatctgatc agtaatatca agggtgagta tcgagataaa aattatttag aatgggctcc
   152521 tattactgaa gaaaaaccag taaaaccgat tgaaaagcaa gtcgaaaaac ctaaaaaggc
   152581 tcctttaggg gttaaaaaag aaggaaagag ctatgcggag gtggcgcgtg aagaagcgcg
   152641 tgcggacttg aaaaagaaac gctctgctaa ctacctaact caggatttca gccttgcgag
   152701 acgtcattct cagcccagtc tagttagaca gggcaatcaa ccgacaactc ctttccaaaa
   152761 ggaaaatcct ggtgaatttg tcaaatatag ccaaaaattg acccagtctc attatatctt
   152821 ggcggaagaa gttcattcta tccctaccaa gaatgaagaa gtgtcagcac ctgctccaaa
   152881 gaaaaacaat tatgattttc taaagaagag ccaaatctac aataaaaaaa gtaaacaaac
   152941 agaacaagaa cgtcgggttg cccaagagtt gaatctgacc agaatgacag aataggggag
   153001 aaaacatgtc aaagacatat cattttatcg gaattaaggg atcagggatg agtgccttgg
   153061 ccttgatgtt gcaccagatg gggcacaagg ttcagggatc agatgttgaa aagtactact
   153121 ttacccaacg cggtcttgag caggcaggaa ttaccattct tccttttgat gaaaagaatc
   153181 tagacggtga tatggaaatt atcgctggaa atgcctttcg tccagataac aacgtcgaaa
   153241 ttgcctatgc ggaccaaaat ggtatcagct acaaacgtta ccatgagttt ctaggtagct
   153301 ttatgcgtga ctttgttagc atgggagtag caggagcaca tggaaaaact tcaacgacag
   153361 gtatgttgtc tcatgtcttg tctcacatta cagataccag cttcttgatt ggagatggga
   153421 caggtcgtgg ttcggctaat gccaaatatt ttgtctttga atctgacgaa tatgagcgtc
   153481 acttcatgcc ttaccaccca gaatactcta ttatcaccaa cattgacttt gaccatccag
   153541 attatttcac aagtctcgag gatgttttca atgcctttaa cgactatgcc aaacaaatta
   153601 ccaagggtct ttttgtctat ggtgaagatg ctgaattgcg taagattacg tctgatgcac
   153661 caatttatta ttatggtttt gaagctgaag gcaatgactt tgtagctagt gatcttcttc
   153721 gttcaacaac tggttcaacc ttcaccgttc atttccgtgg acaaaacttg gggcaattcc
   153781 acattccaac ctttggtcgt cacaatatca tgaatgcgac agccgttatt ggtcttcttt
   153841 acacagcagg atttgatttg aacttggtgc gtgagcactt gaaaacattt gccggtgtta
   153901 aacgtcgttt cactgagaaa attgtcaatg atacagtgat tattgatgac tttgcccatc
   153961 atccaacaga aattattgcg accttggatg cggctcgtca gaaataccca agcaaggaaa
   154021 ttgtagcagt ctttcaaccg cataccttta caagaaccat tgccctgttg gacgactttg
   154081 cccatgcttt aaaccaagca gatgctgttt atctagcgca aatttatggc tcggctcgtg
   154141 aagtagatca tggtgacgtt aaggtagaag acctagccaa taaaatcaac aaaaaacacc
   154201 aagtgattac tgttgaaaat gtttctccac tcctagacca tgacaatgct gtttacgtct
   154261 ttatgggagc aggagacatc caaacctatg aatactcatt tgagcgtctc ttgtctaact
   154321 tgacaagcaa tgttcaatag gatgttccca tggaaattcc aattaagatc attcaggcaa
   154381 gcaagtttga tttgcctgag ataggggcac ttcagacctc gtcttttcca gctgaaaagc
   154441 agcaactttc ccatatttta gaagaaagta tccgtaagtg tgcggatacc tttcttctag
   154501 ctagggatga aaatcaactt ttaggctata ttttatcaag tccccagtca gacaatccgc
   154561 aatgtctaaa agtacattct ttagtcatcg agtctgacca tcagagacag ggcctgggaa
   154621 cacttcttct tgcagccttg aaagaggtgg cagttgagct ggattacaaa gggattcgtt
   154681 tggagagtcc tgatgagctg ctttcctatt ttgaaatgaa cggttttgtt gatgaagaag
   154741 aaattttgct ctatgcaact agccagggct atagtatgat ttggtttaat cccttttatc
   154801 tggaggaaca atgaaaatca gacaagcaag attagaagat ttggatcgga ttgttgaact
   154861 tgaatttgaa aatttttcgg tcgaagaagc cattcctcct tctgtctttg aagcacattt
   154921 gagagaaatt cagacctctt ttctggttgc tgaaaaagaa ggaagaatca tgggttatat
   154981 cgaaggacca gttggcctgc accgccatct gcaagaccag tcttttacag aagaaataaa
   155041 agactatagt catgagcctg gtggttatat ctctgtgacc tgtctgtcta ttgccaagga
   155101 ggcacaggga ctcggactgg gtcagaaatt gctgacagcc ttgaaagaag ttgctcttga
   155161 agatgagaga gatggcatta atctaacctg tcatgactat ctcatcgcct attatgaaaa
   155221 acatggattt gtcaacgaag gccagtccca gtcaaccttt gcaggggaaa catggtatga
   155281 tatggtctgg gaaatgaaaa aataagttag gaaaagtatc atagattgct ttttttggac
   155341 ttttaagata taatattatg gattatcaac aaggaggaaa aacttttgag tgaaaagtca
   155401 agagaagaag agaaattaag ctttaaagag cagattctga gagatttaga aaaagtaaaa
   155461 ggctatgatg aagttctgaa agaagatgag gcagtagttc gcactcctgc aaatgaacct
   155521 tcagctgaag aactcatggc tgattccttg tcaacggtag aggagattat gagaaaagct
   155581 cctaccgtgc ctactcaccc aagtcaaggt gtaccagctt ctccagcaga tgagattcaa
   155641 agagaaactc ctggtgttcc aagtcatcca agtcaagatg taccttcttc tccagcggaa
   155701 gaaagtggat caagaccagg tccaggtcct gttagaccta agaaacttga aagagaatac
   155761 aatgaaaccc caacaagggt agctgtttcc tatacgacgg cagagaaaaa agcagaacaa
   155821 gcaggtccag aaacacctac gcctgctaca gaaacagtgg atatcatcag agatacatca
   155881 cgtcgtagcc gtagagaagg agcaaaaccc gttaagccta agaaagagaa gaagtcacat
   155941 gtgaaagctt ttgtgatttc attccttgta ttccttgcct tgctctcagc aggtggttac
   156001 tttggttacc agtacgtgct agattcctta ttacctatcg atgctaattc taagaaatat
   156061 gtgacggttg gaattccaga aggttcaaac gttcaagaaa tcggtacgac gcttgaaaaa
   156121 gctggtttgg taaagcatgg tctgattttt agtttttatg ccaagtataa aaattatacc
   156181 gacttgaaag caggttacta caatttgcaa aagagtatga gtacagaaga cttactcaaa
   156241 gagttgcaaa aaggtggaac agatgaaccg caagaacctg tacttgcgac tttgacaatt
   156301 ccagaaggtt ataccttgga tcagattgct caaactgtgg gtcaattgca aggtgacttc
   156361 aaagagtctt tgacagcgga ggctttcttg gctaaagttc aagatgagac gtttatcagt
   156421 caagcagtag cgaaatatcc tactttactg gaaagtttgc ctgtaaaaga cagcggtgcg
   156481 cgttatcgtt tggaaggata ccttttccca gctacatact ctatcaagga aagcacaact
   156541 attgagagct tgattgatga gatgttagct gctatggata agaacctatc tccttactat
   156601 agtactatca aatctaaaaa cttgactgtc aatgagttgt tgaccattgc ttccttggtc
   156661 gaaaaagaag gtgccaagac agaagatcgt aagctcattg caggtgtatt ctacaatcgt
   156721 ttgaatcgtg atatgccact tcaaagtaat attgcaatct tgtatgccca aggaaaactg
   156781 gggcaaaata tcagtctagc tgaggatgtt gcgattgata ccaacattga ttcaccttat
   156841 aatgtttata aaaatgtagg tctcatgcct ggtccagtcg atagtccaag tctggatgcg
   156901 attgagtcaa gcatcaatca aactaagagc gataacctct actttgtagc agatgtcaca
   156961 gaaggcaagg tctactatgc taacaatcaa gaagaccacg accgcaatgt cgctgaacat
   157021 gtcaacagca aattaaacta aacaaactaa aattatgtga tacttcacat aattttcttt
   157081 agaaaatatt atcagaagaa agttgagaaa aatggcagaa aaaacatatc ctatgaccct
   157141 tgaggaaaag gaaaaacttg aaaaagaatt agaagaattg aaattggttc gtcgaccaga
   157201 agtggtagaa cgcattaaga ttgcccgttc atacggtgac ctttcagaaa acagtgagta
   157261 cgaagcagct aaggatgaac aagcctttgt cgaaggacaa atctctagct tagaaacaaa
   157321 aatccgctat gctgaaatcg tcaatagcga cgcagttgcc caggacgaag tagcgattgg
   157381 taaaacagtc accatccaag aaattggtga ggacgaagaa gaagtttata ttatcgtagg
   157441 ttcagctggt gcggatgcct ttgcaggtaa ggtttcaaat gaaagcccaa ttgggcaggc
   157501 cttgattggc aagaaaacag gtgatacagc aaccattgaa acgcctgttg gtagctatga
   157561 tgtaaaaatc ttgaaggttg aaaaaacagc ctaaaaacag aaaaaggagt ggggaggcga
   157621 tgtgcttcac tcactccttt ttccattttg ctactcttcg aaaatctctt caaaccacgt
   157681 cagcgtcgcc ttgccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
   157741 acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt ttattgagta
   157801 ttagatgtat agtgcattga agttaaaata gtacactttg atttctaaga cattgttaga
   157861 aattagatta aattccttaa tcgatttgcg catgttttat ttcatttcac tatactttag
   157921 attggaaaat aaggaatcac ataaatcgca agaaataggg aatctgattc gtgtttataa
   157981 ccgttcaaaa agagaagagg ctgaaagtga gccacttaat ctttatgtcg aagatgaaaa
   158041 gggcaatctc ctggcaggtt tgatagcaga gacttttgga aattggctag aaatcgagta
   158101 tttgtttgta aaagaggaac tgcgagggca aggaatcggt tcaaaactat tgcaacaggc
   158161 agaaagtgaa gctaagaatc gaaattgttg ttttgccttt gtcaatactt accagttcca
   158221 ggcaccggac ttttatcaga aacatggcta caaggaagtt ttttctttgc aagactatct
   158281 ctacattagg caaagatatt attaccaaaa gaatctgtaa ggtgagtatg gaggtataat
   158341 acaaagagag gctcgcacat aagtatggag gtggactgat gtatatgagt aactattgat
   158401 aaataccagt tataacctag aaattgtgtc tttctagacg atattgagga caatataatc
   158461 gtagccccaa aattaggaat caagacttat caggttaaga aaagaagtga tgttgttgat
   158521 attttaaaca atttatttaa actaaaaact ctctatctat taatccgaga ttcccctctc
   158581 ggattttgtg ttgctttcat taaatttaca ggtaagactt gctagcttca gtaaatatac
   158641 acaagttttt cagaatagag tgaaatccaa aagaaaatgg aaataatgaa agctcttgta
   158701 ggcataagaa aacacctctg tgttatactt gttgttcaac cacaaacaca agaaaggcac
   158761 agaaatgcaa gacaattata ctacaaaagg taaacatttg acaatcgata gccgtcgctt
   158821 aatcgaaaga tggaaaaaag aaggaaaatc aaatagagaa attgcctctc tacttggaaa
   158881 agctcctcaa actatccaca ctaaaatcaa gcgtaggaca gtccgaaaat gtcttggaaa
   158941 agggcgcttc aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaataatcg
   159001 caagcactcg gtcaagagat caagcgtgac caaggaacta aaggaaaaga ttctccacta
   159061 tcataaccaa aaatttttgc ctgaaatgat ggttatggct aaaggggtta acgtgggaat
   159121 ttcaaccatt tactattgga ttcatcatgg aaaattgggg taaagcaagc aggatctgct
   159181 ttaccctaga aaaggaaaag cgcttaagaa acaggccagc accaacttta aacctgctgg
   159241 tcaatccatc gaacagcggc ctgaagctat caattttcgc ttggagaatg ggcattatga
   159301 gattgatacg gttctactta cgagagcgaa aaactactgc ttgcttgtct tgacggatcg
   159361 aaaaagtaga catcagatca tccgattgat tccaaataaa agtgctgagg tggtcaatca
   159421 ggctctaaaa ctcatcttaa aacaacacaa gattctttcc atcacggcag ataatggaac
   159481 ggaattcaat cgcttgtcta atgtattttc tgaggagcac atttattatg cacatcccta
   159541 tgcctcttgg gaaaggggaa ctaatgagaa tcacaacagg ctcattcgta gatggttacc
   159601 taagggaacc aagaaaatga ctcccaaaga agtcgcattc atcgaaaagt ggattaacaa
   159661 ctatcctaaa aaatgcttgg actacaagtc acccagagaa gacttctgga tggctaactt
   159721 gaacttgaaa tttagcaaaa tggaaataat ttttattaaa cgcttccaat agcggttaaa
   159781 agttgacaaa tttaaatttt aggactacac taagtaagta aattttattt taaaggagaa
   159841 tttgttatga atttaacatt tttaggctta tgtattgcct gtatgggcgt atctgtcggt
   159901 gaaggtttat tgatgaatgg actgtttaaa tcagtagcac gccaaccaga tatgctttct
   159961 gagtttcgta gtttgatgtt tttaggtgtt gcctttattg aaggaacttt ctttgtaact
   160021 cttgtcttct catttattat caaataaata catggaacga gaagaaaagg gaggatttta
   160081 gatggaagaa agtattaatc caatcatctc tattggtcct gttatcttca atctgactat
   160141 gttagccatg actttgttga ttgtgggagt tatttttgtc tttatttatt gggcaagccg
   160201 caatatgacc ttgaaaccca aaggaaagca aaatgtactt gagtatgtct atgactttgt
   160261 tattggattt acagaaccta acattggttc gcgctacatg aaagattact cactcttttt
   160321 cctttgttta ttccttttca tggtgattgc caataacctt ggcttaatga caaagcttca
   160381 aacgatcgat gggactaact ggtggagttc gccaaccgct aatttacagt atgacttaac
   160441 cttatctttt cttgtcattt tgttgacaca tatagaaagc gttcgtcgtc gtggatttaa
   160501 aaaaagtata aaatctttta tgagtcctgt ttttgtcata ccgatgaata tcttggaaga
   160561 atttacaaac ttcttatctt tggctttgcg gatttttggg aatatctttg caggagaggt
   160621 catgacgagt ttgttacttc ttctttccca ccaaactatt tattggtatc cagtagcctt
   160681 tggagctaat ttggcttgga ctgcattttc tgtctttatt tcctgcatcc aagcttatgt
   160741 ttttactctt ttgacatctg tgtatttagg gaataagatt aatattgaag aggaatagaa
   160801 aggagtaact gatgcacgta acagtaggtg aattaattgg taattttatt ttaatcactg
   160861 gctcttttat tcttttgcta gtcttgatta aaaaatttgc atggtctaat attacaggca
   160921 ttttcgaaga aagagctgaa aaaattgctt cagatattga cagagctgaa gaagcccgtc
   160981 aaaaagcaga agtattggct caaaaacgcg aagatgaatt ggctggtagc cgtaaagaag
   161041 ctaagacaat cattgaaaat gcaaaggaaa cagctgagca aagtaaggct aatatcttag
   161101 cagatgctaa actagaagca ggacacttaa aagaaaaagc caatcaagaa attgctcaaa
   161161 ataaagtaga agctttacag agtgttaagg gtgaggtcgc agatttgacc atcagcttag
   161221 ctggtaaaat catctcacaa aaccttgaca gtcatgccca taaagcactc attgatcagt
   161281 atatcgatca gctaggagaa gcttaatgga caagaaaaca gtaaaggtaa ttgaaaaata
   161341 cagcatgcct tttgtccaat tggtacttga aaaaggagaa gaagaccgta tcttttcaga
   161401 cttgactcaa atcaagcaag ttgttgaaaa aacaggtctg ccttcttttt taaaacaagt
   161461 ggcagtagac gagtcggata aggaaaaaac aattgctttt ttccaagatt ctgtgtcgcc
   161521 tttattacaa aactttatcc aggttctggc ctacaatcac agagcaaatc ttttttatga
   161581 tgtgcttgta gattgcttga accgacttga aaaagaaaca aatcgatttg aagtgacgat
   161641 tacgtctgct catcctctaa ctgatgaaca gaagactcgt ttgctccctt tgattgagaa
   161701 aaaaatgtct ctgaaagtaa ggagtgtaaa agaacaaatc gatgaaagtc tcattggtgg
   161761 ttttgtcatt tttgccaatc acaagacaat tgatgtgagt attaaacaac aacttaaagt
   161821 tgttaaagaa aatttgaaat agaaagtggt gttcttttgg caattaacgc acaagaaatc
   161881 agcgctttaa ttaagcaaca aattgaaaat ttcaaaccca attttgatgt gactgaaaca
   161941 ggtgttgtaa cctatatcgg ggacggtatc gcgcgtgctc atggccttga aaatgtcatg
   162001 agtggagagt tgttgaattt tgaaaacggc tcttatggta tggctcaaaa cttggagtca
   162061 acagacgttg gtattatcat cctaggtgac tttacagata tccgtgaagg cgatacaatc
   162121 cgccgtacag ggaaaatcat ggaagtccct gtaggtgaaa gtctgattgg tcgtgttgtg
   162181 gatccgcttg gtcgtccagt tgacggtctt ggagaaatcc acactgataa aactcgtcca
   162241 gtagaagcac cagctcctgg tgttatgcaa cgtaagtctg tttcagaacc attgcaaact
   162301 ggtttgaaag ctattgacgc ccttgtaccg attggtcgtg gtcaacgtga gttgattatc
   162361 ggtgaccgtc agacagggaa aacaaccatt gcgattgata caatcttgaa ccaaaaagat
   162421 caagatatga tctgtatcta cgtcgcgatt ggacaaaaag aatcaacagt tcgtacgcaa
   162481 gtagaaacac ttcgtcagta cggtgccttg gactacacaa tcgttgtgac agcctctgct
   162541 tcacaaccat ctccattgct cttcctagct ccttatactg gggttgctat ggcggaagaa
   162601 tttatgtatc aaggtaagca tgttttgatt gtatacgatg atctatcaaa acaagcggta
   162661 gcttatcgtg aactatcgct cttgcttcgt cgtcctccag gtcgtgaagc cttcccaggg
   162721 gatgttttct atctccacag ccgtttgctt gagcgctcag ctaaagtttc tgatgaactt
   162781 ggtggtggat caattacagc cctaccattt atcgagacac aagcaggaga tatctcagcc
   162841 tatatcgcaa ccaacgtgat ttctatcact gatggacaaa tcttccttgg cgatggcctc
   162901 ttcaatgcag gtattcgtcc agccatcgat gcgggttcat ctgtatctcg tgtaggtggt
   162961 tctgcacaaa tcaaagccat gaagaaggtt gctggtacac ttcgtatcga ccttgcttca
   163021 taccgtgagt tggaagcctt tactaagttt ggttctgact tggacgcagc aacacaggct
   163081 aagttgaacc gtggacgtcg taccgttgag gtcttgaaac aacctgttca caaaccatta
   163141 cctgttgaga aacaagtaac cattctttat gctttgacac atggtttctt ggatactgtt
   163201 ccagtagatg atattgttcg tttcgaggaa gagttccatg ccttctttga tgctcaacat
   163261 ccagagattt tggaaaccat tcgtgataca aaagacttgc cagaagaagc agtcttggat
   163321 gctgcgatta cagagtttct caatcaatct agcttccaat aagaatagag gtgtcagatg
   163381 gcagtgtctc taaatgatat taaaacaaaa atcgcctcaa caaaaaatac gagtcaaatc
   163441 actaatgcca tgcaaatggt atcggctgct aagttaggtc gctctgaaga agctgctcgc
   163501 aacttccaag tttacgctca gaaagtgcgt aaacttttga cagatatcct tcatggtaat
   163561 ggagctggtg cttcaactaa tccgatgttg attagccgtt ctgtgaagaa gacaggctat
   163621 atcgttatca cttcagaccg cggtttggtt ggaggttata attcctctat tttgaaagct
   163681 gttatggagt tgaaagaaga ataccaccca gacggtaaag gttttgaaat gatctgtatc
   163741 ggtgggatgg gagctgattt ctttaaggct cgcggtattc aaccacttta tgaattacgt
   163801 ggcttggcag accaacctag ctttgatcaa gttcgtaaga ttatttcaaa aactgttgaa
   163861 atgtaccaaa atgaactctt tgatgagctt tatgtttgct acaaccacca tgtcaatacg
   163921 ctaaccagtc aaatgcgtgt ggaacaaatg cttccgattg ttgacttgga tccaaatgaa
   163981 gcggatgaag agtacagctt gacttttgaa ttggaaacca gccgagaaga aattctggag
   164041 cagttgttgc ctcagtttgc agaaagtatg atttacggtg ccattatcga tgccaagaca
   164101 gctgagaatg ctgcgggtat gacagccatg caaacagcga cagataatgc taagaaagtc
   164161 atcaatgatt tgacaattca gtataaccgt gccagacagg cggcgattac acaagaaatt
   164221 acagaaatcg tagcaggtgc tagtgcctta gaataggccc tagtccagct cgtatgaaaa
   164281 tgaacttagg acctagttga gctaggaacc gacagtatct tatatagaat aggagaagga
   164341 gatgagttca ggtaaaattg ctcaggttat cggtcccgtt gtagacgttt tgtttgcagc
   164401 aggggaaaaa cttcctgaga ttaacaatgc acttgtcgtc tacaaaaatg acgaaagaaa
   164461 aacaaaaatc gtccttgaag tagccttgga gttaggagat ggtatggttc gtactatcgc
   164521 catggaatca acagatgggt tgactcgtgg aatggaagta ttggacacag gtcgtccaat
   164581 ctctgtacca gtaggtaaag aaactttggg acgtgtcttc aacgttttgg gagataccat
   164641 tgatttggaa gctcctttta cagaagacgc agagcgtcag ccaattcata aaaaagctcc
   164701 aacttttgat gagttgtcta cctcttctga aatccttgaa acagggatca aggttattga
   164761 ccttcttgcc ccttacctta aaggtggtaa agttggactt ttcggtggtg ccggagttgg
   164821 taaaaccgtc ttaatccaag aattgattca caacattgcc caagagcacg gtggtatttc
   164881 agtatttgct ggtgttgggg aacgtactcg tgaggggaat gacctttact gggaaatgaa
   164941 agaatcaggc gttatcgaga aaacagccat ggtctttggt cagatgaatg agccaccagg
   165001 agcacgtatg cgtgttgccc ttactggttt gacaatcgct gaatacttcc gtgatgtgga
   165061 aggccaagac gtgcttctct ttatcgataa tatcttccgt ttcactcagg ctggttcaga
   165121 agtatctgcc cttttgggtc gtatgccatc agccgttggt taccaaccaa cacttgctac
   165181 ggaaatgggt caattgcaag aacgtatcac atcaaccaag aagggttctg taacctctat
   165241 ccaggctatc tatgtgccag cggatgacta tactgaccca gcgccagcaa cagccttcgc
   165301 tcacttggat tcaacaacaa acttggaacg taagttggta caattgggta tctacccagc
   165361 cgttgaccca cttgcttcaa gctcacgtgc cttggcacct gaaatcgttg gagaagagca
   165421 ctatgcagtt gctgctgaag taaaacgtgt ccttcaacgt taccatgaat tgcaagatat
   165481 cattgctatc cttggtatgg atgagctttc tgatgaagaa aagaccttgg ttgctcgcgc
   165541 ccgtcgtatc cagttcttct tgtcacaaaa cttcaacgtt gcggaacaat ttactggtca
   165601 gccaggttct tatgttccag ttgctgaaac tgtacgtggc tttaaggaaa tccttgatgg
   165661 taaatacgac cacttgccag aagatgcctt ccgtggtgta ggttctatcg aagatgtgat
   165721 tgcaaaagct gaaaaaatgg gattttaaga ggtgatctat ggctcagtta actgtccaga
   165781 tcgtgacacc agatggtctc gtctatgatc accatgccag ctatgtatcg gttcgaactc
   165841 tggatggtga gatggggatc ttgccacgac atgaaaatat gattgcagtt ttagcagttg
   165901 atgaagtaaa ggtaaaacgt atcgatgata aagatcacgt gaactggatt gcagtaaacg
   165961 gtggtgttat tgaaattgcc aatgatatga tcacaatcgt cgctgactct gcagaacgtg
   166021 ctcgtgatat cgatatcagt cgtgcagaac gtgccaaact tcgtgcagaa cgtgccaaac
   166081 ttcgtgcaga acgtgcaatt gaagaagcac aagacaaaca tttgattgac caagaacgtc
   166141 gtgctaagat tgctttgcaa cgtgctatta accgtattaa tgtcggaaat agactataag
   166201 aaaaaatgaa cttgaaaata ccaagttcat tttttatggt gttttaagga gcaaaacgga
   166261 tgcagactgc ttcgggaaca tggaagtcgt tggagagttc tgctagacga ccattgtcac
   166321 aattacgttt aaagacagtt gcattgtcag agtcttgatg gacaacaatg agaaattttt
   166381 ggtcgggtgt caaatcaaaa tcacgtggag tctgaccatg cgttggaacg atttctaata
   166441 actctaagct accgtccgca aggatggtat atactgcgat agaatcatgg ccacggttag
   166501 aagcgtagag gtatttaccg tctttagaga gatgaatagc agcggttcca ttaaagcctt
   166561 cgtaagcttc cggtaaagtt gaaatgacct gcatacgttc aaattcgcca acgccatcgt
   166621 agattaaaac ttcgatagta ctattgagtt cacaaatgag ataagcgatt ttatagtggt
   166681 tatggaaaat gatatggcgt gagcctgctc ctggcttgct gtgataggta tagagcttag
   166741 ataattttcc ttcttgatcg aggtcatagg tgatgacttg gtcagttccc aagtcgcagg
   166801 tcactagata gtggtcaggt gttaaatctg tatagtgaac atggggggaa gcttgatttt
   166861 catgtggacc ttggccactg tgttgatcca tatcactaag tagaagacta ccatcttcct
   166921 ggcgtttata aacaaggact tgtcccttgt gatagttggc tgcgtaaacc aaatcacgct
   166981 tttcatcgac agcaacataa cagtggggag ctccttcttc aacaacatga tttaacacag
   167041 tcccgtcagt ttgataggct gcaattcccc ccttatcgtc ttggctacca acagtgtata
   167101 aatgttggtg ctggtcaaag gcaaggtagg ttggacttgg ctcagctgca aaaagttcta
   167161 gatttgaaag ctgaccagtt tctgtatcaa agtctgcctt gtaaatccct tgagaagtac
   167221 gacgtgtata agttccaaaa taaacagttt ctttcattac tatacctctg tgtaaagata
   167281 agactattat atcacaaaaa caagcaaatt aaagacattc aattagatgt aagcacttta
   167341 aaaaagagtt attttgtttc aaaaatggta taatgagaga acaatagaaa ggaagtattt
   167401 atggagcaaa aagagaaaca ttttagccta tcttggtttt tcaagtggtt tttagataac
   167461 aaggcaatta cggtattttt agtaacctta ttattgggat tgaatctttt tattttaagt
   167521 aagattagtt ttctattttc acctgtttta gactttttag cagttgtgat gttgccagtc
   167581 attttgtctg gtttgttata ttatttgttg aatcctattg ttgattggat ggagaagcat
   167641 aaggttaatc gtgttatagc tatcactatt gtctttgtta tcatcgctct ctttatcatt
   167701 tggggcttgg cagtcgccat tccaaatctg caacgtcagg ttttgacctt tgcaagaaac
   167761 gttcctgttt acttagaaga tatagatagg attgttaatg gattggtagc ccagcatctg
   167821 ccagatgatt tcagacctca attagagcaa gttttgacca atttttctag ccaggctaca
   167881 gttttggcaa gtaaggtttc atctcaggca gtcaactggg tgagtgcctt tattagcggg
   167941 gcttctcaag tgattgttgc cttgattatc gttcctttca tgctctttta tctcttgcgt
   168001 gatgggaaag gcttgcgtaa ctatttgacc caattcattc caagaaaatt gaaggaacct
   168061 gttggacaag ttctatcaga tgtgaatcaa cagttgtcca actatgttcg agggcaagtg
   168121 acagtggcta ttattgtagc agtaatgttt atcatcttct tcaagattat tggtctacgc
   168181 tatgcggtta cgctgggggt tactgctggt attttaaatc tggtccctta tcttggtagc
   168241 tttctagcca tgcttcctgc cctagtattg ggtttgattg ctggtccagt catgcttttg
   168301 aaagtagtga ttgtctttat tgtagaacaa actattgaag gccgttttgt ctctccattg
   168361 attttgggaa gtcaattaaa catccaccct attaatgttc tctttgtttt gttaacttca
   168421 ggatctatgt ttggtatctg gggagtttta cttggtattc cagtttatgc ctctgctaag
   168481 gttgtcattt cagccatttt cgaatggtat aaggtagtca gtggtctata tgaattagag
   168541 ggtgaggaag tcaagagtga acaatagtca acagatgtta caggctttgg aggagcaaga
   168601 tttaactaag gctgagcatt atttcgccaa agctttagaa aatgattcaa gtgatcttct
   168661 gtatgagttg gcaacttatc ttgaagggat tggtttctat cctcaggcca aggaaattta
   168721 cctgaaaatt gtagaggatt ttccagaggt tcatcttaat ctagctgcaa ttgctagcga
   168781 ggatggtcaa atagaagaag cctttaccta tcttgaggaa atccaagctg acagtgactg
   168841 gtatgtctcg tctttggttt tgaaggcaga cctttaccag ctggaaggtt tgacagatgt
   168901 ggcacgtgag aaattattgg aggccttgac ctactcagag gattctctct tgatattggg
   168961 tttggcagag ttggatagtg agttggaaaa ttaccaagcg gctattcaag cctatgccca
   169021 gttagataat cgctcgattt atgagcaaac gggcatttcc acctatcaac gaattggctt
   169081 tgcctatgct cagttaggga aatttgaaac ggctactgag tttttagaaa aagccctgga
   169141 gttagaatac gatgacttaa cagcttttga gttggccagt ctttattttg atcaagaaga
   169201 atatcaaaaa gccaccctct actttaagca gcttgatacc atttctcctg actttgaagg
   169261 ctatgagtat gggtacagtc aggctttaca taaggaacat caagttcaag aagccctgcg
   169321 tatcgctaag caaggattag agaaaaatcc ctttgaaact cgcctcttgc tagctgcttc
   169381 acaattttct tatgaattgc atgatgctag tggtgcagaa aattatctcc ttactgcaaa
   169441 agaagacgct gaggatacag aagaaatctt gcttcgttta gccactattt atctggagca
   169501 ggagcgttat gaggatattc tagacttgca gagtgaggag ccagaaaatc ttttgaccaa
   169561 gtggatgatt gctcgttctt atcaagaaat ggacgatttg gatactgctt atgagcatta
   169621 tcaagagttg acaggagatt tgaaggacaa tccagaattt ctggaacact atatctatct
   169681 cttgcgtgaa ttgggacatt ttgaagaagc aaaagtccat gctcacactt acttaaaact
   169741 ggttccagat gatgtgcaaa tgcaagaact gtttgagaga ttgtaagaat gtttaaacat
   169801 atagaactgt agtttatctc ttttgatagc tgcggttttt atttgtatat ggtagaatct
   169861 ttttacaaaa atacttggta atcttgttta ttcatgctat aataggaaca attactttta
   169921 ggaggtgcag tatgtcttat ttatttgaga tattaccgag tttactgaat ggtgcgagca
   169981 cgactgtaca ggtctttgca ctggtcttgc tattttcgat tccgttgggc gttttgattg
   170041 cctttgcctt gcaagtccat tggaagcccc tccattatct gattaacatt tacatctggg
   170101 ttatgcgagg aaccccctta ctcttgcaac tgatttttat ctattatgtg ctcccaagta
   170161 ttgggattcg tttagaccgc cttcctgcag ctattattgc ctttgttctc aactatgcag
   170221 cttactttgc agaaattttc cgtgggggaa ttgacactat tccaagagga cagtatgagg
   170281 ctgccaaggt cttgaagttt agcccttttg acagagtgcg ctatattatc ttgccccaag
   170341 tgaccaagat cgttcttcct agtgtcttta atgaagttat gagtttggtc aaggatactt
   170401 ctttggtcta tgctctcgga atttcagacc ttatcttggc tagtcgaaca gctgctaacc
   170461 gcgatgctag tctggttcct atgttcttgg caggagccat ttacttgatt ttaattgggg
   170521 ttgtgacaat tatttccaaa aaagttgaga agaagtatag ttattataga tagggggcag
   170581 ctatgttaga attacgaaat atcaataaag tctttggaga caaacaaatc ctgtctgatt
   170641 tcagtctaag tattcctgaa aagcaaatcc tggctatcgt tggaccttct ggtggaggta
   170701 agacaactct tttacgtatg cttgcaggtc ttgaaaccat tgattcaggg caaatctttt
   170761 ataatggaca acctttagag ctagatgaat tgcagaagcg caacctactg ggatttgtct
   170821 tccaagattt tcaactattt cctcatctat cagttctgga aaatttgact ttatcgcctg
   170881 tgaagaccat gggaatgaag caggaagagg ctgagaagaa ggcgagtgaa ctcttggaac
   170941 agttaggact aggaggacac gcagaggcct atcctttctc actatctggt gggcaaaagc
   171001 agcgggtggc tttggcgcgt gctatgatga ttgacccaga aatcattggc tacgatgaac
   171061 caacttctgc cctggatcca gaattacgtt tggaagtgga gaagctaatc ttgcaaaata
   171121 gggaacttgg gatgacccag attgtggtta cccatgattt gcagtttgct gaaaatatcg
   171181 cagatgtatt attgaaagta gaacctaaat aggaggaaaa atggatgaaa aaatggatgc
   171241 ttgtattagt cagtctgatg actgctttgt tcttagtagc ttgtgggaaa aattctagcg
   171301 aaactagtgg agataattgg tcaaagtacc agtctaacaa gtctattact attggatttg
   171361 atagtacttt tgttccaatg ggatttgctc agaaagatgg ttcttatgca ggatttgata
   171421 ttgatttagc tacagctgtt tttgaaaaat acggaatcac ggtaaattgg caaccgattg
   171481 attgggattt gaaagaagct gaattgacaa aaggaacgat tgatctgatt tggaatggct
   171541 attccgctac agacgaacgc cgtgaaaagg tggctttcag taactcatat atgaagaatg
   171601 agcaggtatt ggttacgaag aaatcatctg gtatcacgac tgcaaaggat atgactggaa
   171661 agacattagg agctcaagct ggttcatctg gttatgcgga ctttgaagca aatccagaac
   171721 ttttgaagaa tattgtcgct aataaggaag cgaatcaata ccaaaccttt aatgaagcct
   171781 tgattgattt gaaaaacgat cgaattgatg gtctattgat tgaccgtgtc tatgcaaact
   171841 attatttaga agcagaaggt gttttaaacg attataatgt ctttacagtt ggactagaaa
   171901 cagaagcttt tgcggttgga gcccgtaagg aagatacaac cttggttaag aagataaatg
   171961 aagctttttc tagtctttac aaggacggca agttccaaga aatcagccaa aaatggtttg
   172021 gagaagatgt agcaaccaaa gaagtaaaag aaggacagta agataaaata gtggctgaaa
   172081 ctgcgttttg attagcaaaa cgtagttttt ttgtaatcta ggaaaacgat aatagcgatt
   172141 gaatctggat aatt
//
LOCUS       DBERAE010000002        90842 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.02, whole genome shotgun sequence.
ACCESSION   DBERAE010000002 DBERAE010000000
VERSION     DBERAE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 90842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.02"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..162
                     /locus_tag="ACL70N_000171"
     CDS             <1..162
                     /locus_tag="ACL70N_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HGS0589066.1"
                     /translation="IMSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPW
                     TKVVQEKCK"
     gene            complement(617..1981)
                     /locus_tag="ACL70N_000172"
     CDS             complement(617..1981)
                     /locus_tag="ACL70N_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589067.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(1969..2526)
                     /locus_tag="ACL70N_000173"
     CDS             complement(1969..2526)
                     /locus_tag="ACL70N_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0589068.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            complement(2427..3056)
                     /locus_tag="ACL70N_000174"
     CDS             complement(2427..3056)
                     /locus_tag="ACL70N_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS0589069.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYIVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            complement(3067..4788)
                     /locus_tag="ACL70N_000175"
     CDS             complement(3067..4788)
                     /locus_tag="ACL70N_000175"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589070.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            complement(4772..6526)
                     /locus_tag="ACL70N_000176"
     CDS             complement(4772..6526)
                     /locus_tag="ACL70N_000176"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589071.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6686..7678
                     /locus_tag="ACL70N_000177"
     CDS             6686..7678
                     /locus_tag="ACL70N_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0589072.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            complement(8193..9383)
                     /locus_tag="ACL70N_000178"
     CDS             complement(8193..9383)
                     /locus_tag="ACL70N_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS0589073.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGSDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(9380..9964)
                     /locus_tag="ACL70N_000179"
                     /pseudo
     CDS             complement(9380..9964)
                     /locus_tag="ACL70N_000179"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            10561..11847
                     /locus_tag="ACL70N_000180"
     CDS             10561..11847
                     /locus_tag="ACL70N_000180"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGS0589074.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     TLIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            11862..12173
                     /locus_tag="ACL70N_000181"
     CDS             11862..12173
                     /locus_tag="ACL70N_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGS0589075.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            12408..13136
                     /locus_tag="ACL70N_000182"
                     /pseudo
     CDS             12408..13136
                     /locus_tag="ACL70N_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            13471..14362
                     /locus_tag="ACL70N_000183"
                     /pseudo
     CDS             13471..14362
                     /locus_tag="ACL70N_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            14378..15106
                     /locus_tag="ACL70N_000184"
     CDS             14378..15106
                     /locus_tag="ACL70N_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589076.1"
                     /translation="MKLNKFNFIKENIRDLYSSGVIYLGLIISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            15492..15701
                     /locus_tag="ACL70N_000185"
     CDS             15492..15701
                     /locus_tag="ACL70N_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0589077.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            15691..16179
                     /locus_tag="ACL70N_000186"
     CDS             15691..16179
                     /locus_tag="ACL70N_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGS0589078.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            16295..17755
                     /locus_tag="ACL70N_000187"
     CDS             16295..17755
                     /locus_tag="ACL70N_000187"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGS0589079.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            17752..18576
                     /gene="nadE"
                     /locus_tag="ACL70N_000188"
     CDS             17752..18576
                     /gene="nadE"
                     /locus_tag="ACL70N_000188"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGS0589080.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            18873..19424
                     /locus_tag="ACL70N_000189"
     CDS             18873..19424
                     /locus_tag="ACL70N_000189"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589081.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            20468..20689
                     /locus_tag="ACL70N_000190"
     CDS             20468..20689
                     /locus_tag="ACL70N_000190"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS0589082.1"
                     /translation="MKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVT
                     TITYNVDGKSGQVTESTLSQKKRLSNKSC"
     gene            20885..21274
                     /locus_tag="ACL70N_000191"
     CDS             20885..21274
                     /locus_tag="ACL70N_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS0589083.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(21935..22963)
                     /gene="queA"
                     /locus_tag="ACL70N_000192"
     CDS             complement(21935..22963)
                     /gene="queA"
                     /locus_tag="ACL70N_000192"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGS0589084.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            23114..23821
                     /locus_tag="ACL70N_000193"
     CDS             23114..23821
                     /locus_tag="ACL70N_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGS0589085.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            23899..24408
                     /locus_tag="ACL70N_000194"
     CDS             23899..24408
                     /locus_tag="ACL70N_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589086.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSKADMEEMV
                     NYIINHYEE"
     gene            24488..24664
                     /gene="rpsU"
                     /locus_tag="ACL70N_000195"
     CDS             24488..24664
                     /gene="rpsU"
                     /locus_tag="ACL70N_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGS0589087.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            24794..25729
                     /gene="hprK"
                     /locus_tag="ACL70N_000196"
     CDS             24794..25729
                     /gene="hprK"
                     /locus_tag="ACL70N_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGS0589088.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            25722..26510
                     /gene="lgt"
                     /locus_tag="ACL70N_000197"
     CDS             25722..26510
                     /gene="lgt"
                     /locus_tag="ACL70N_000197"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGS0589089.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            26511..26937
                     /locus_tag="ACL70N_000198"
                     /pseudo
     CDS             26511..26937
                     /locus_tag="ACL70N_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            26910..27299
                     /locus_tag="ACL70N_000199"
     CDS             26910..27299
                     /locus_tag="ACL70N_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGS0589090.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            27383..28513
                     /gene="hemW"
                     /locus_tag="ACL70N_000200"
     CDS             27383..28513
                     /gene="hemW"
                     /locus_tag="ACL70N_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGS0589091.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            28518..29255
                     /locus_tag="ACL70N_000201"
     CDS             28518..29255
                     /locus_tag="ACL70N_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGS0589092.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            29266..30039
                     /locus_tag="ACL70N_000202"
     CDS             29266..30039
                     /locus_tag="ACL70N_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGS0589093.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            30029..30646
                     /locus_tag="ACL70N_000203"
     CDS             30029..30646
                     /locus_tag="ACL70N_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGS0589094.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            30856..31257
                     /locus_tag="ACL70N_000204"
     CDS             30856..31257
                     /locus_tag="ACL70N_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGS0589095.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            31257..31535
                     /locus_tag="ACL70N_000205"
     CDS             31257..31535
                     /locus_tag="ACL70N_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGS0589096.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            31525..32298
                     /locus_tag="ACL70N_000206"
     CDS             31525..32298
                     /locus_tag="ACL70N_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGS0589097.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            32299..33603
                     /locus_tag="ACL70N_000207"
     CDS             32299..33603
                     /locus_tag="ACL70N_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGS0589098.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            34177..35055
                     /gene="pstS"
                     /locus_tag="ACL70N_000208"
     CDS             34177..35055
                     /gene="pstS"
                     /locus_tag="ACL70N_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGS0589099.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            35055..35972
                     /gene="pstC"
                     /locus_tag="ACL70N_000209"
     CDS             35055..35972
                     /gene="pstC"
                     /locus_tag="ACL70N_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS0589100.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            35962..36846
                     /gene="pstA"
                     /locus_tag="ACL70N_000210"
     CDS             35962..36846
                     /gene="pstA"
                     /locus_tag="ACL70N_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS0589101.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            36857..37660
                     /gene="pstB"
                     /locus_tag="ACL70N_000211"
     CDS             36857..37660
                     /gene="pstB"
                     /locus_tag="ACL70N_000211"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0589102.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            37673..38431
                     /gene="pstB"
                     /locus_tag="ACL70N_000212"
     CDS             37673..38431
                     /gene="pstB"
                     /locus_tag="ACL70N_000212"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0589103.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            38443..39096
                     /gene="phoU"
                     /locus_tag="ACL70N_000213"
     CDS             38443..39096
                     /gene="phoU"
                     /locus_tag="ACL70N_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS0589104.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            39253..40068
                     /locus_tag="ACL70N_000214"
     CDS             39253..40068
                     /locus_tag="ACL70N_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0589105.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(40088..41359)
                     /locus_tag="ACL70N_000215"
     CDS             complement(40088..41359)
                     /locus_tag="ACL70N_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGS0589106.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            41501..42232
                     /gene="budA"
                     /locus_tag="ACL70N_000216"
     CDS             41501..42232
                     /gene="budA"
                     /locus_tag="ACL70N_000216"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGS0589107.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            42242..42994
                     /locus_tag="ACL70N_000217"
     CDS             42242..42994
                     /locus_tag="ACL70N_000217"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS0589108.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            43106..44056
                     /gene="murB"
                     /locus_tag="ACL70N_000218"
     CDS             43106..44056
                     /gene="murB"
                     /locus_tag="ACL70N_000218"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGS0589109.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            44115..45272
                     /locus_tag="ACL70N_000219"
     CDS             44115..45272
                     /locus_tag="ACL70N_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589110.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            45253..46059
                     /locus_tag="ACL70N_000220"
     CDS             45253..46059
                     /locus_tag="ACL70N_000220"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589111.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            46056..46829
                     /locus_tag="ACL70N_000221"
     CDS             46056..46829
                     /locus_tag="ACL70N_000221"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589112.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            46826..47896
                     /locus_tag="ACL70N_000222"
     CDS             46826..47896
                     /locus_tag="ACL70N_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0589113.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            48157..48396
                     /locus_tag="ACL70N_000223"
     CDS             48157..48396
                     /locus_tag="ACL70N_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589114.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            48671..49156
                     /locus_tag="ACL70N_000224"
     CDS             48671..49156
                     /locus_tag="ACL70N_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGS0589115.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            49178..51796
                     /gene="alaS"
                     /locus_tag="ACL70N_000225"
     CDS             49178..51796
                     /gene="alaS"
                     /locus_tag="ACL70N_000225"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGS0589116.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(51886..53340)
                     /locus_tag="ACL70N_000226"
     CDS             complement(51886..53340)
                     /locus_tag="ACL70N_000226"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGS0589117.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            53519..54268
                     /locus_tag="ACL70N_000227"
     CDS             53519..54268
                     /locus_tag="ACL70N_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589118.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            54249..55883
                     /locus_tag="ACL70N_000228"
     CDS             54249..55883
                     /locus_tag="ACL70N_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589119.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            56568..57731
                     /locus_tag="ACL70N_000229"
     CDS             56568..57731
                     /locus_tag="ACL70N_000229"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGS0589120.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            57728..58405
                     /gene="aroD"
                     /locus_tag="ACL70N_000230"
     CDS             57728..58405
                     /gene="aroD"
                     /locus_tag="ACL70N_000230"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGS0589121.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            58395..59249
                     /locus_tag="ACL70N_000231"
     CDS             58395..59249
                     /locus_tag="ACL70N_000231"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGS0589122.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            59268..60335
                     /gene="aroB"
                     /locus_tag="ACL70N_000232"
     CDS             59268..60335
                     /gene="aroB"
                     /locus_tag="ACL70N_000232"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS0589123.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            60345..61511
                     /gene="aroC"
                     /locus_tag="ACL70N_000233"
     CDS             60345..61511
                     /gene="aroC"
                     /locus_tag="ACL70N_000233"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGS0589124.1"
                     /translation="MRYLTAGESHGPRLTAIIDGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            61521..62624
                     /locus_tag="ACL70N_000234"
     CDS             61521..62624
                     /locus_tag="ACL70N_000234"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGS0589125.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            62635..62973
                     /locus_tag="ACL70N_000235"
     CDS             62635..62973
                     /locus_tag="ACL70N_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGS0589126.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            63065..64348
                     /gene="aroA"
                     /locus_tag="ACL70N_000236"
     CDS             63065..64348
                     /gene="aroA"
                     /locus_tag="ACL70N_000236"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGS0589127.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLSPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            64341..64817
                     /locus_tag="ACL70N_000237"
     CDS             64341..64817
                     /locus_tag="ACL70N_000237"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGS0589128.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            64814..65662
                     /gene="pheA"
                     /locus_tag="ACL70N_000238"
     CDS             64814..65662
                     /gene="pheA"
                     /locus_tag="ACL70N_000238"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS0589129.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            65659..66933
                     /gene="psr"
                     /locus_tag="ACL70N_000239"
     CDS             65659..66933
                     /gene="psr"
                     /locus_tag="ACL70N_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGS0589130.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     RNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            67212..68057
                     /locus_tag="ACL70N_000240"
     CDS             67212..68057
                     /locus_tag="ACL70N_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0589131.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            68047..69150
                     /locus_tag="ACL70N_000241"
     CDS             68047..69150
                     /locus_tag="ACL70N_000241"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0589132.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            69152..70138
                     /locus_tag="ACL70N_000242"
     CDS             69152..70138
                     /locus_tag="ACL70N_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0589133.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            70154..71587
                     /locus_tag="ACL70N_000243"
     CDS             70154..71587
                     /locus_tag="ACL70N_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGS0589134.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            71616..72650
                     /locus_tag="ACL70N_000244"
     CDS             71616..72650
                     /locus_tag="ACL70N_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS0589135.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            72792..73529
                     /gene="mecA"
                     /locus_tag="ACL70N_000245"
     CDS             72792..73529
                     /gene="mecA"
                     /locus_tag="ACL70N_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGS0589136.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            73680..74966
                     /locus_tag="ACL70N_000246"
     CDS             73680..74966
                     /locus_tag="ACL70N_000246"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGS0589137.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVVHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            74968..75837
                     /gene="thrB"
                     /locus_tag="ACL70N_000247"
     CDS             74968..75837
                     /gene="thrB"
                     /locus_tag="ACL70N_000247"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGS0589138.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            76087..77025
                     /gene="msrB"
                     /locus_tag="ACL70N_000248"
     CDS             76087..77025
                     /gene="msrB"
                     /locus_tag="ACL70N_000248"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS0589139.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            77083..78807
                     /locus_tag="ACL70N_000249"
     CDS             77083..78807
                     /locus_tag="ACL70N_000249"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589140.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            78809..80560
                     /locus_tag="ACL70N_000250"
     CDS             78809..80560
                     /locus_tag="ACL70N_000250"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589141.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            80907..82166
                     /locus_tag="ACL70N_000251"
     CDS             80907..82166
                     /locus_tag="ACL70N_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGS0589142.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    82242..82377
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            82416..82916
                     /gene="rplJ"
                     /locus_tag="ACL70N_000252"
     CDS             82416..82916
                     /gene="rplJ"
                     /locus_tag="ACL70N_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGS0589143.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            82992..83360
                     /gene="rplL"
                     /locus_tag="ACL70N_000253"
     CDS             82992..83360
                     /gene="rplL"
                     /locus_tag="ACL70N_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGS0589144.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            83547..83717
                     /locus_tag="ACL70N_000254"
     CDS             83547..83717
                     /locus_tag="ACL70N_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589145.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            83717..83965
                     /locus_tag="ACL70N_000255"
                     /pseudo
     CDS             83717..83965
                     /locus_tag="ACL70N_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            83979..84319
                     /locus_tag="ACL70N_000256"
                     /pseudo
     CDS             83979..84319
                     /locus_tag="ACL70N_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            84312..84692
                     /locus_tag="ACL70N_000257"
     CDS             84312..84692
                     /locus_tag="ACL70N_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS0589146.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            84705..84938
                     /locus_tag="ACL70N_000258"
                     /pseudo
     CDS             84705..84938
                     /locus_tag="ACL70N_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            84941..85528
                     /locus_tag="ACL70N_000259"
     CDS             84941..85528
                     /locus_tag="ACL70N_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0589147.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            85730..85867
                     /locus_tag="ACL70N_000260"
     CDS             85730..85867
                     /locus_tag="ACL70N_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS0589148.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            86157..87560
                     /locus_tag="ACL70N_000261"
     CDS             86157..87560
                     /locus_tag="ACL70N_000261"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HGS0589149.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            87749..88333
                     /locus_tag="ACL70N_000262"
     CDS             87749..88333
                     /locus_tag="ACL70N_000262"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589150.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDI"
     gene            88382..89122
                     /locus_tag="ACL70N_000263"
     CDS             88382..89122
                     /locus_tag="ACL70N_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589151.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            89125..90444
                     /locus_tag="ACL70N_000264"
     CDS             89125..90444
                     /locus_tag="ACL70N_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589152.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLGDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            90578..90715
                     /locus_tag="ACL70N_000265"
     CDS             90578..90715
                     /locus_tag="ACL70N_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS0589153.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT        27296 a        16239 c        19214 g        28093 t
ORIGIN      
        1 attatgagtt tgttggaaac agctaaacgt catcaactaa atagtgagaa atatctatcc
       61 tatcttctag aatgtcttcc aaacgaggaa actctcgtaa acaaagaagt tttagaggct
      121 tatttaccat ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc cagattagga
      181 actatccgtg agttctctag tctggagatt tttcaataga cttcgttatt gggcggttac
      241 aatttattat atgaaaatcc catatcattc tccaattcta tattttacct ttctaaatgt
      301 atagattaac cacctaatta tagcatataa agcagattcc tttcaatcgt atgatttact
      361 gcattaaatt aagtaaaaaa ataaaggcag tccgaagact gccgatattt atctctcatc
      421 tctttaatta tggtaagtaa ataaagaatt tccctaaaga tatggaaatt attaatacta
      481 taaatacata ttataaagtt tataaatact gtaaaaatcc tgaagttaat tttctaataa
      541 atatcaatat gtgttagtat cttttaaatt tttagacaat ttactagttc tatagacatg
      601 tttaacagac tctattttac aattcaaaaa tttcatctgc cacttcattt aaaaattcta
      661 tatcatggga aacaataaaa attattttat ccatggtttt atacttatta atcagttcag
      721 atatttttat catattggaa taatccatac cacttgaagg ttcgtcaaaa aagacaaatg
      781 gagaattctt gcacataaca gatgctattg caagcctttg cttttgccct cctgataaac
      841 tcatcggatg cctttcaata aattcgtcca ggcctaaatc ttttaagatg attttcgcct
      901 tttcttcatc aaaattcttt actcctaatc taagctcgtt gaatacttca tctgtgaata
      961 attgatgatt tacatcttgc ataacaagtg aagagttttt gagtctttct tttttagata
     1021 gcttctctcc cttaaaataa atttcttctt ttgatttttt ctcaagacct attaaacatc
     1081 ttaaaagcgt tgattttcct cgtccgttgg atcctattat gccataaatt ttcccaagct
     1141 tgaacgaaat atcttttaag cttaaacact catcatcagt aaatttgtag ctaagatttt
     1201 ttatctgata ctctccacct tcttttaaat aaggaacttt taatttactt aattctttat
     1261 ctcttaaact taaagcattt aattcatttt tatctagctt taaaaattca cttctagtat
     1321 aagttttttt aagctttcct ttatctatta aaaatacacg gtcaactatg tccatcaaat
     1381 aataaattct atgctctgca acaattatgc ttatgccttt ctcttttaat atctttagca
     1441 tctttgccaa aacacttatg cttttaatat ctaaattcga tgaaggctca tccataacta
     1501 taatctttgt acctgctata taagaagctg caatgcaaag aatttgtttt tcaccgccgg
     1561 atagattaaa tatatttctg tttaaaagat tttttatcgg gaatatctca agcatatcct
     1621 tcaaacgcct gtccatctct tctcttgcaa gaccgatatt ttccaaataa aataataatt
     1681 ctaatgtcgt attgacatta aaaaaatatg tcttaggatt ttgaaaaaca gttgaaacaa
     1741 gcattgagat ttgataaagt tccaaatttt ttatattctt accatcaata attatttcgc
     1801 cctttgtctt tgcgttgtca taccttacag ctagtccatt gattgaattt attaaagatg
     1861 acttaccatt tccacttttt cctgtaaata gcacgcactc tccctcggct atggatagtg
     1921 atatatcatc taatatatgc tcttcaccat aatcaagact taaatttttt atttcaacca
     1981 tattaatcct cccacaataa gtccagcaac cgctaaaaca taaacaaaat caattagctg
     2041 tatctttacg cgaatgtatc tggtcttggc aattggattt tctattgcct ttgtttctgc
     2101 cgcttttgca atgtcatctg atatattaga tgatataatg agtagtggca cagaaacata
     2161 ttcaagatat ttgactgggt ttttaaaatt tatccctctt actctcatag ccattttgat
     2221 gtttttcttc tcctccttaa aagatgggaa gaatctaaac ataaccgcaa taggtatgga
     2281 tacattcttt gaaatcttaa gcttatccat cgatgaaatt attgcgccta catccgaggt
     2341 ctttatcata aagcttgctg ccataaatgg taaaataaac attctaataa caataggtat
     2401 actcaaaaac atcttaacta tagggtttaa ttcagataac accataaaat taggcaagga
     2461 gtaaagtatc ccacacaata taatccattt gaaaagtgtt ttttcaatag agccttgcct
     2521 atatatgctc caagaattcc tcctaagaaa gcacctaagg ctactaaagc catgtgagga
     2581 taagttatta acttttctaa tacatcaaca taatcttttc ccatcgtcat caaagaccac
     2641 tccatatatt tttcttttgc taaaagcatt tgcattaaag agctacatat ccatgtgctg
     2701 aagattgcat aagaaagcat attgtattta aatgaattat aattaccaat ctttctaatt
     2761 aattctgcta ttatcattac tataagtgat aaaaccacaa ctatgtaggt atgaccagct
     2821 gcaaacatca caagtggtga tatcatacca aatataaata gtgcccatgg cttttgaacc
     2881 ttagccataa ataacataac aacagttcct gcaactatgg ctaatactgt cgggtatatt
     2941 aagaacaata ttggaatcaa gcccatcata ccaactccaa acatgaaggc aaaataaatt
     3001 acgccaaaaa caccgatact tactaaatct tttactttta attttttatt atccattgta
     3061 gtcctcctaa taaataaatt cttctgccat ttttgtcttt tctattaaat ttttgtaaat
     3121 ttttgatttt tgtaaaagct cttcatgctt accttcgctt tctactcttc cgttttgaag
     3181 aactactatc ttgtctgcat tttctatgga tttcattcta tgtgaaatga ttacaacagt
     3241 tttatcttta actaaattat ttaaagactc ttgaatcttt ttctcgttgt taacatcaag
     3301 gcttgctgtt atctcatcta agatcaatat cggcgcatct tttaagaagg ctctggctat
     3361 tgataatctt tgtctttctc ctcctgatag ctcagctccg ttctcaccaa taactgtatc
     3421 gaaaccttta tccatttttt ctataaaatc tgtgcaattt gcaagttttg ctgctctttt
     3481 aacctcttcg tcacttgcat cttgctttcc gattctaata ttttccataa cgctttgatt
     3541 aaagagaacc acatcttgga aaactataga gaccttatca aaaagagatt ctgttgatat
     3601 ttcttttata tctttgccat cgattaagat ttgtcccttg tcataatcat aaagtcttga
     3661 tataagtttc aagatagttg ttttaccgca gccacttgca cctaccaaag cagtgacctc
     3721 tccctgctta gctttaaaac ttacaccatt taaaactttt gcgtctttat tgtaggcaaa
     3781 ctcaacatct tttagatcaa tatcaaattt ttttaagcta tagtcatcgc cttcttgtaa
     3841 atcttgattt tgaatttctt ttaatctttc tattttgggc gataaataaa atatttccat
     3901 caagccctct ttagatgcat ctaaagagtc ttttatcttc atagcagcta gtaaatatcc
     3961 tataaggtag agagaattta tctctttatt aataattaga tttacgccga caaatatcac
     4021 aacagcaaga gatataaagc taaatattga agatatagac aaagttaaaa ttgtagttac
     4081 ttccgccttt aagtgtactc tctcactatc ttccattttt ttatataagt catctttaat
     4141 atccttcgat aaattatatg ctttaatctc catttgcatt tcgatatttt cttgaaagct
     4201 ttctgagttt tttcttaaga catcataata tctattctgt ccattaacct gatatttttt
     4261 agataaaggt ataaatataa agcttaaaat agatggaata attacagcta aacccatctt
     4321 gacattgccc gctagcatca ttacagatat taatgggaaa aacagtacca tgccgcccac
     4381 ctttggtatt gagtggctca ttgcatgctc tatgccttca atatcagcca tgattgtttg
     4441 tgaaatgtcg gaaatgtcat gtttagaaaa gtaagataga ggtaattttg ataaattctc
     4501 cgctgtcctt attcttaaat ctgcactttc ttgataggtt gtgttatata atttatcgta
     4561 ttcgatagaa agcaaaatat acattgctat caaagtcaaa actgagaata ctatataaaa
     4621 gccattgctt ttgcccatat tttccaaaac ttcctgagca aaaatcataa gtaatatggc
     4681 aggaagcatg tttatacaat aaacgaaaaa tgaagccagt gttgctttac ttaaatttct
     4741 tgctcctcca tctgtaagag caaatctttt tttataaaac tctttcattt gaaaccctcc
     4801 attcattcgc actgttaaac atctcttgca ggctcttata ccttgtatct tttgacatta
     4861 attctttgtc agaccctctt tctataattt ttccactatc catgacaata atttcatcaa
     4921 ggtctttaat tgtagatagc ctgtgtgcaa tcatgataac tgttttatcc ttcataagat
     4981 ttttaaaagc tttttgcaat tcaaactcgt tatctgggtc aatagatgct gatgcttcat
     5041 ccataataat aattttggaa tcctttaaaa ttgctctagc aattgcaatt ctttgttttt
     5101 ctccaccgga taaataaaca ccttttgagc ctatgattgt attttctctt tctgggaatt
     5161 tgtctaatat taaatcgcat cctgctaatt ttaaggctct cataacgtca tctttcgtcg
     5221 catctttatt agctaaagct acattatcat aaatgctctt cttgaataat tttgaatctt
     5281 gaaaaacaaa ggaaatggct ttaattaagg cttcgtcaga atattcactt attgctatcc
     5341 cgcctatctt tatgcttcct tcattaacat tgtaaaaacc tgatataagt tttgctactg
     5401 ttgatttgcc tgatccagat gaaccgacaa gtgcgtagga ctttccttct tctaaattaa
     5461 aggataaatt ttcaatgaca gctttatcat tataagcaaa gctaacattc tcaaattcta
     5521 tattatagtt tttaaaatta ttgacattac catgcactaa tttgtctttt tgcatatctt
     5581 cgtaaagcgc ctctaaagta tctactgcat aatttccttg agaaatatac atggagtacc
     5641 acatcattct catgaatgaa acaaagagaa ctcctgataa aaataaaatc atgataagct
     5701 caagtaaaat cacctttgcg ctagctaagc tagtcataaa ataaactata ggaataatta
     5761 aaattgcaat cagtccaaaa aataaccatt gatacaaaac ataaggcctt ttacaagata
     5821 gggaataatc ataagcatac tttgagtaat cttttatagc cttgtaaaag cttttaaatg
     5881 actctacatt tgctttaaat atttttacaa cttgcattcc tctcacgtac tcaacagttt
     5941 cagcacttag tttagatagg gattcttggt atatcttcat aaattcttgc tcgcccatca
     6001 tcgcccctaa aattaagcca ccaattatag taagagcaag caaaattatg ccaactctta
     6061 tacttactat aaagccaagt gcaagtacaa gtacgggtgt gattattgcc tgagaactat
     6121 cgggaatcat gtgtgctacc acctgatgag tttgtgctgc attatcatct atgatctttc
     6181 ttatttgacc agatggattt aagtcaaaga acctaaaact tgctttttcc agaccatcga
     6241 ttcccctttt tcttaaattt gtttcaagcc tgaatcccaa gatatgtgaa aacattcctg
     6301 agacaaaata aaatatcgct ccacttgtta gtgtaataac agattttaat gctatactct
     6361 ctgcaccgga taaatttgaa ttaattatta acttatctag aaatttgtag attaaataat
     6421 atccatatac tgtaagtaga gcagatatag cagaaaaaat tatggccaaa accccaagat
     6481 atttcttatc ttggacataa gcaaatagtt ttttgtaaat cttcataagc atatctcctt
     6541 tctttaatat cccttttaga tataaattcg cttaattgat aatatctatc attgcttttc
     6601 tattatacat ctgttataat tactaataca atagttttga attaataagg ctaattggaa
     6661 tattgtctaa aagggatagt gtgttatgtc atattatgat tttgtaaaag attatatgaa
     6721 agtagatgaa tgtaaaaaca atgagaagta ttcaagtgca ggtcatacat tttgttggaa
     6781 aaaagagaat tcaacttatg cagaaggcct atattggttt tatgaaggag gcagcttcat
     6841 tatcgatata catgattttt atatcaaaga ggaagtagtt caaaatagca cttatagtat
     6901 gtcagactat gtttcaattt attcaagtta cattgtcagt gcaaacggag aaaagtttaa
     6961 tccgtatcaa actattaccg caaactctct atgtactttt gattttgata atataaaaga
     7021 tgattttgtt tttttattac acgagaattg ttgttatctt gctgtttcca ttggttttaa
     7081 aaaagagcta atagaaaaac atttagcatc tattaacatt aatccagaat ctttttattc
     7141 aaccttgctt caaccgaatc aaataatact tacaaaggcc ttagaaagag tggcaatgga
     7201 aatattaaat tgtaagatgg acgctcctgc cgctgatttt ttctttaaag caaaggcaaa
     7261 tgaatggata agtatagtaa ttgacacata cttaaataga aaaaaatata aaattgaaat
     7321 tgatgatgat aaagcacttg aagatgtagc aagattctta gatgatcatt ttgcaacgaa
     7381 tgtaaatcaa ggcacgcttg aaaaaatatc taaaatgagt ggtactaaat taaaaaattt
     7441 atttaaggaa aaatattgtc aaagcattac agagtacact caaagaaaaa gaatgaatgt
     7501 agctgaaact cttcttttaa acactgaact acctataaaa gagatagcag aatctgttgg
     7561 atattcatct gccagcaaat tttctatcta ttataaaaga tacaagggaa aacttccaag
     7621 tgaagtccgt aatttagctt gcaaacatca caattttaaa tgcgattatt gtgattaaag
     7681 taatttttta caagccatgt ttttatatga atttaagtgt atatgtgcat atatagtctg
     7741 aataaatttg atttgaaaaa tggataaaaa aataaaggca gtccgaagac cgccaatatt
     7801 tatctctctg cacctttgct atggtctttc ttatttgact tagatttgtc atctgtctta
     7861 aagcttttta tttgccctaa tatggacttt ttatccttgt cttgactctt tacttgttct
     7921 tttgctttta agagcttaga agacaaaaag agatattata ttaaaacaat atttctccgg
     7981 tactgggact gggacgggac taaaaatctg aaaacgtcct ataattaggt ggatttagtg
     8041 atattataaa aaatagaatc tagtattttg aatggttttg gatatattgt acgtttggaa
     8101 aagaagaatg ggagtaattt taaactaaca aaaaaatgct ttgaaatcag tgtttcagag
     8161 catttttgtt ctttctgtaa ataatttgca aactatagta actgttgact tttacttaac
     8221 catttttcga ttgtaagttc aaaatggtca actactatta tattttcagg aatcgtatca
     8281 aaatcaaata ataaattatc tgaatgagtt tttataacta ctccaaaatc aagttttttg
     8341 gagtttatag cattctgtaa taaagagata ctctcattca gacattcatt atttttttga
     8401 atttttatag gtatcggttt tttttgaaaa tgtttaggta aaaaaccatc aattccttta
     8461 tttctttgaa caatttttgc ctgtaataat ttaagaatgt tttcctcttc ctcagttttg
     8521 gttctatatg cttcgattcc tttattcaat aaatttgaac ttgtttttat aacattttcc
     8581 agacgttgct gagttatatt gatagcttcc tcagataaat caatccccat ataatttcta
     8641 ttcaaaatct tggaggctac taaagtagtt ccacttccac agaacgggtc taaaactata
     8701 tcatttttat cagtagcaat ctttataatt tgttctaata acagaatagg tttttgtgta
     8761 ggataaccta ctctttcttt agcttttgga ttaagaaatg gtatattcca aacatctgaa
     8821 aggggaactc catttttctc ttttgctaga atatagttac cattattatc aactttatat
     8881 atagttttag agtttccatc tcgttttcgt tccactagta tttggtcgat atttgtagta
     8941 gaagaatact ctgtaaaaat tgtattaaat ttaaaatctt ttgactttga ataaaagtaa
     9001 atgttttgat gattgttcaa taatcccttt tttgaattag accaccgttt atagttccat
     9061 ataatttcgc tttgaaacat atctgatcca aagatattat ctaaaattaa tctaatatga
     9121 tgatttgcaa ttttatcaca atgaacgaaa atgctgccac tattttttag cactcttttg
     9181 cattcttcta atcttacaga caaaaattct ttgtaatcct caatcgaagt ccacgtatct
     9241 tcgaatgaat acataatatt tttgttatta gataattttt gggttttctg tgtaaagaaa
     9301 ggagggtcca tatagattaa atcaatactt gaggattcaa tagtttttaa tatttctaag
     9361 ttatctcctt ttaatactgt cattttgatt ttacccctgt ttttttattt gcaatatctg
     9421 ttagaatact aagtaaatca ataccggtca ctgctcttaa atgttcccag gcagaatctc
     9481 cataataata tttccctcca ataccgttat acaatgtttc taaagtttgc tgaattttta
     9541 tagcttgagt tctatttgga tagtagaaca ttaaccgaat tggtatatat cctttgttat
     9601 gaataacttt tattctagtg tgttctttag ttatatggtc tccatctgta gttgcatccc
     9661 accattttat ttcgtatgcg tgtttttttc cgactaaaca atcaatttca aaagtcttag
     9721 gttttgtact ttcagaatta ggaatgttaa ctttttaagt attttctgta ccaaattttt
     9781 cgttaaagga tagtactgca gcttcttcta aaaattaacc agcatatttg tataaaaaac
     9841 gacctttatt ttgatacaaa tcgatatttt ctccttcttc aaatgaaata cctaaaactc
     9901 tgtatatcaa ataatggctc ttattatcat ttgccatttc acgaactctc tcttgaactt
     9961 tgatgtttaa gttatcagaa tatttcttag ctaatttttc gattttttct ttctaattcg
    10021 gtcatttcta tcctcttgtt ataaataaaa ttatagctat atctattata acatggttta
    10081 ataaattctt tgagcttttt tctttttaaa tattgattgt ttctaaaagt tctagtaata
    10141 ttgctatttc tcatttttcc aaatatgtta ttcaacttat tagctacgtc tctattcata
    10201 tttgggtata aaacaaaaaa tcaattctaa cagttttata tcagaataat aaataaaaaa
    10261 gcgatattct agactgtatc aatccttttc cattatagga gcaacagagt gggagtagtc
    10321 atctaaggac taatttatgt atttttacga gtcagtatct ttggatactg gtttttactt
    10381 ttctagactt tttgactact tgttaaaact gggataattt tcgactgttt aacagttatt
    10441 atgcaaagtc taaaagatta gaattgtcaa aacaatccgt ctaggcttga ttttatcctt
    10501 tatttactat aaaatgagaa ggaaaaatgt caaactttta tattgcaaat aggagaaatt
    10561 atgacaaaaa cattaaaacg tcctgaggtt ttatcacctg cagggacttt agagaagcta
    10621 aaggtagctg ttcagtatgg agcagatgct gtctttatcg gtggtcaggc ctatggtctt
    10681 cgtagccgtg cgggaaactt tactttcgaa cagatggaag aaggcgtgca gtttgcggcc
    10741 aagtatggtg ccaaggtcta tgtagcggct aatatggtta tgcacgaagg aaatgaagct
    10801 ggtgctggtg agtggttccg taaactgcgt gatatcggga ttgcagcagt tatcgtatct
    10861 gacccaacct tgattatgat tgcagcgact gaagcaccag gccttgaaat ccacctttct
    10921 acccaagcca gtgccactaa ctatgaaacc cttgagttct ggaaagagct aggcttgact
    10981 cgtgtcgttt tagcgcgtga ggtttcaatg gaagaattag ctgaaatccg caaacgtaca
    11041 gatgttgaaa ttgaagcctt tgtccatgga gctatgtgta tttcatactc tggacgttgt
    11101 actctttcaa accacatgag tatgcgtgat gccaaccgtg gtggatgttc tcagtcatgc
    11161 cgttggaaat acgaccttta cgacatgcca tttgggaaag aacgtaagag tttgcagggt
    11221 gagattccag aagaattttc aatgtcagcc gttgacatgt ctatgattga ccacattcca
    11281 gatatgattg aaaatggtgt ggacagtcta aaaatcgaag gacgtatgaa gtctattcac
    11341 tacgtatcaa cagtaaccaa ctgctacaag gcggctgtgg atgcctatct tgaaagtcct
    11401 gaaaagtttg aagctatcaa acaagacttg gtggacgaga tgtggaaggt tgcccaacgt
    11461 gaactggcta caggatttta ctatggtaca ccatctgaaa atgagcagtt gtttggtgct
    11521 cgccgtaaaa ttcctgagta caagtttgtc gctgaagtgg tttcttatga tgatgcggca
    11581 caaacagcaa caattcgtca acgaaatgtc attaacgaag gggaccaagt tgagttttat
    11641 ggtccaggtt tccgtcattt tgaaacctat attgaagatt tgcatgatgc caaaggcaat
    11701 aaaatcgacc gcgctccaaa tccaatggaa ctattgacta ttaaggtgcc tcaacccgtt
    11761 caatcaggag acatggttcg tgcattaaaa gaaggactca tcaatcttta taaggaagat
    11821 ggaaccagcg tcacagttcg agcttaagaa aggaaaagga aatgatagag gcacagggtt
    11881 tcttagtgga taagcaaaca agatgcattc attaccatag caagctggat attattgctt
    11941 tacaatgcta tgattgtaaa aagtattatg cttgttatcg gtgtcatgat tcattagaaa
    12001 atcacccttt tgagccgtat cccttatctt tgatacagga taagcctatt ttatgtggtg
    12061 tttgtctaaa actactaaca tataagcaat ataaagaaag cttaagttgc cccttttgtt
    12121 tttctcgctt taatccaggt tgccaaaatc ataaggaacg ctattttaaa tagcaaatca
    12181 tctagttttg aagtaggaga aaactcaatt ccaagagaaa atgaagtaaa tcttcccaca
    12241 ataaaacgca taatatcaag attgttcaat acctgatact atgcgttttt aagattttaa
    12301 agactttttt cctttatctg gtattttgac tacttgttaa aactgggtta attttcaact
    12361 gtttaacagt tattatgcaa agtctaaaag attagaattg cgtctagagt atgcgtgatg
    12421 ccaaccgtgg tggatgttct cagtcatgcc gttggaaata cgacctttac gatatggcat
    12481 ttgggaaaga acgtaagagt ttgcagggtg agattccaga agaattttca atgtcagccg
    12541 ttgacatgtc tatgattgac cacattccag atatgattga aaatggtgtg gacagtctaa
    12601 aaatcgaagg acgtatgaag tctattcact acgtatcaac agtaaccaac tgctacaagg
    12661 cggctgtgga tgcctatctt gaaagtcctg aaaagtttga agctatcaaa caagacttgg
    12721 tggacgagat gtggaaggtt gcccaacgtg aactggttac aggattttac tatggtacac
    12781 catctgaaaa tgagcagttg tttggtgctc gtcgtaaaat tcctgagtac aagtttgtcg
    12841 ctgaagtggt ttcttatgat gatgcgacac aaacagcaac cattcgtcaa cggaacgtca
    12901 ttaacgaagg ggaccaagtt gagttttatg gtccaggttt ccgtcatttt gaaacctata
    12961 ttgaagattt gcatgatgcc aaaggaaata aaatcgaccg cgctccaaat ccaatggaac
    13021 tattgactat taaagtccca caacctgttc aagctggaga catggttcga gctcttaaag
    13081 aggggcttat caatctttat aaggaagatg gaaccagcgt cacagttcgt gcttaatgta
    13141 gttgtttagt tttaaaaaat tatgcaaagc tccatataca acacttaaac gagattaaag
    13201 aatggcgaaa tcccctgatg cgcaagagat tagctgtctt ttttattttt taagtgataa
    13261 agtcggagct taggtatcaa agcctatcaa attaaacaaa gaagcgatgt cttagatatt
    13321 ttgaaaaaaa ttaataagca gaaaactctc tattattttg ttgtatagag ttttttgtta
    13381 ataaaatttc acaaaatgac atttatacat tgcattaagt tagatatatg atataatatt
    13441 gttaaaaaga ggcgcaactt tttaaaatta atgagaatca aagagaaaac caataatatt
    13501 aatggaggaa taaaaaatgt aagttataaa tgtaagtaag cattatggtc attcaatcat
    13561 tctcaaagac ataaattttg cacttaacaa gggtgaaatt gttggtcaag tagggagaaa
    13621 tggagttggt aagagtacgt tgatgaaaat tcttgttcag aataatcaac cgacttcagg
    13681 taatattata agcagtgata atgttgggta tttaatcgaa gaaccaaaat tatttttatc
    13741 taaaacaggt ttagagaatt taaaatattt gtcaaattta tatggtgttg actacaatca
    13801 agaaagattt agaagtttga tccaagagtt agatttgact cagtctatta ataaaaaagt
    13861 aaagacctat tctttgggta caaaacaaaa attagctttg cttctaactc tcgttacgga
    13921 acctgatata ttgattttag atgaaccgac taatggttta gatattgaat catcacaaat
    13981 agttttatcg gttctaaaaa atttagcttt acatgaaaat gtgggaattt taatatcgag
    14041 tcataaatta gaagatattg aagaaatttg tgagagggtt cttttcttgg agaacgggct
    14101 tttgacattt caaaaagtag gaaaagatag tcataatttc ttgtttgaga tagctttttc
    14161 atcagctaca gatagagaca ttttcattac caaacaagaa tttggggata ttgttcagga
    14221 agagggactg agaattacta tgtctgggaa tattcaaagt agtgagcttt ttaaattttt
    14281 taacgaaaac tctattaaag tagttgattt tgaaactaaa aaagagatgc ttaaagatat
    14341 ttatctaaat cgttcaaaat aaaggaaggt tataatcatg aaattaaata aatttaattt
    14401 tattaaggaa aatataaggg atttatattc atcaggcgta atatatctcg gtttgattat
    14461 ctcgtttata ccgccgatat tgcttacatt ctttattcta aagactcaag ggacatcgct
    14521 tggtattaag catatttcaa acttttatgc tatgctcggt atgttaatgg ctgttataca
    14581 tgctaaccga attattagca gggatttttc ccacaatacg atcagtttat tttataatca
    14641 acagaaaaat cggatgattt acctcttgtc taattttcta tatgccatct cagtttccat
    14701 tatttatgct ttgaatggca ttgtgttact agtcatagta agtaaattgg gtattccagg
    14761 tgatttagga ttagatttta tagtagctat tgtagtcaat acaattttgt tagtcctgtt
    14821 ttattttcta ttatcttaca ttttctattt atacaaattg aaaagtggct tggtatttgg
    14881 tattttagta gctttactac tctttatccc taatatatta aatacgatga tgatgaatac
    14941 tagtaatgat ttgtttatca aagcaattga acttcttcct ttttattctt tacctgtatt
    15001 tgtgacttca aatacgatgt ctattagtca gtatcttgtg gtaatcacta caatcatttt
    15061 attgtacttt ttcactctca agaaaagcaa gaagtattca ttttagtttc atttagtatt
    15121 attttgcata cctaaaatac aataaaaaaa tcagtcatct tggtatgctc ctgctttcac
    15181 tattcaacac gtttttgact tatactaggc tcatttccaa aagcattata taatagtgat
    15241 atgaaaccaa ctaaactaaa caagaaatat aagcaataaa aactcgttta aaagattcta
    15301 ctaaagctaa tactaaataa aaataaaaga gtaaactagg aagtttattt caaacaacct
    15361 aaaatactga ttttcggctg aagataatac tggagtgcaa attaatgggg ttataataaa
    15421 tagctgatag cttgtgttgg ttttggattt tttaagagta gatgagtatt aaaactataa
    15481 ggaggacgaa ggtggctaaa aatttaaaat taaaattagc tcgggtagag cgtgatttaa
    15541 cacaaggtca actggcagag gctgtcgggg tgacacgcca gactattggt ttgatagagg
    15601 cgggaaaata caatcccagt ctctcgctct gccagtctat ttgcagatgt ttagggaaaa
    15661 ccctagacca actattttgg gaggaagaag atgaaaaata gattttatta ttatcaatta
    15721 ctagacgaaa gagaagaaca actgttcaat aaagcgggct ctgaaagttt ctatatctgc
    15781 attgctttgt cgctcctatc ttatatcatt tcagtattag caccaagcct ttttaattct
    15841 aatatgctgc taatcgttat catcataggg acattttact ttttcaatcg tgcccgttat
    15901 ctgggagtga cctactatag tcgttttcat tttacgattt tgggttgttt tttcctaacc
    15961 ttggctatta cggctctttt gatgttgcag aattatcaat tcaacataga aatttatcag
    16021 cacaatcctt tgaattttaa atacctgtct gcttgggtca ttacttatgt catttacctt
    16081 ccgtgggtct ttattggcaa tcttggtctt aagagctatg gcgaatgggc tcagaaaaaa
    16141 tttgaacaag atatggatga attggagagt ggagaatagc ttgttactct tttctcaatc
    16201 cagctaaaat gtgatataat agtattaatt tattggaata catgaaagtt cttgaaaatt
    16261 ttcatgggtt tctagctaag gaagtaggaa aagtatgtat ccagatgata gtttgacatt
    16321 gcacacggac ttgtaccaga tcaacatgat gcaggtttac tttgaccaag ggattcacaa
    16381 taagaaggcg gtctttgagg tgtatttccg ccaacagcct tttaagaacg gctatgcggt
    16441 ttttgcaggt ttggaaagaa ttgtgaacta tcttgaagac ttgcgttttt cagatagtga
    16501 tatagcctat ttggagtcgc ttggttatca tggggcgttc ttggattacc ttcgcaattt
    16561 caagttggag ttgaccgttc gttctgccca agaaggggat ttggtttttg ctaatgaacc
    16621 gattgtgcag gtggaaggac ctctagccca atgtcagttg gtcgaaacgg ctcttttgaa
    16681 catcgtcaac taccagacct tggtggcgac gaaggcagct cgtattcgtt cggttatcga
    16741 agatgaaccc ttgatggagt ttgggacacg tcgggctcaa gaaatggatg cggccatctg
    16801 gggaacacgc gcagctgtga ttggtggcgc caatggaacc agcaacgtgc gtgcgggtaa
    16861 gctctttgac attcctgttt tgggaaccca tgcccatgcc ttggtacagg tttatggaaa
    16921 tgactatgaa gctttcaagg cttacgctgc gacccacaaa aattgtgtct ttcttgtgga
    16981 tacctatgac acccttcgca tcggtgtacc agctgccatt caggtggcgc gtgagctggg
    17041 tgatcagatt aactttatgg gtgtgcggat tgactctggg gatattgcct acatttctaa
    17101 gaaagtccgt cagcaactgg acgaggctgg atttacagag gctaagattt atgcttctaa
    17161 tgatttggac gaaaatacta tcctcaacct caagatgcaa aaggccaaga ttgatgtctg
    17221 gggcgtgggt accaagctga ttacagcata tgaccagcca gctcttgggg cggtttacaa
    17281 gattgttgca atcgaagatg aaactggtca gatgcgcaat acgattaagc tgtctaataa
    17341 tgctgaaaaa gtctctacgc caggtaagaa gcaggtgtgg cgcattacca gtcgtgaaaa
    17401 aggtaagtca gaaggtgact acatcactta tgatggtgtg gatattagct acatgacaga
    17461 aatcaagatg ttccatccga cctatacata catcaagaag acggttcgta attttgatgc
    17521 cgttcctctc ttggtggata tcttcaaaga aggaatatta gtttacaact tgcctagttt
    17581 gactgacatt caggattatg cccgtaaaga atttgacaag ttgtgggatg agtataagcg
    17641 tgtgctcaat ccgcagcact atccagtgga tttggcgcgt gatgtatggc aagataagat
    17701 ggacttgatt gataagatgc gcaaggaagc ccttggtgaa ggagaagaag aatgagtttg
    17761 caagaaacga ttatccaaga gctgggtgtc aaaccagtga ttgatgccca ggaagaaatc
    17821 cgtcgttcta ttgatttctt aaaaagatat ctgaaaaaac atcccttcct aaaaaccttt
    17881 gtactaggga tttctggggg acaagactca accttggcag ggcgtttggc gcaattagct
    17941 atggaagaac tgcgagctga aacgggagac gacagctaca aatttatcgc tgtccgcctg
    18001 ccatacggag tgcaagctga tgaagcagat gctcaaaaag ccctagcctt catccagcca
    18061 gatgtcagct tggttgtgaa tatcaaggaa tcagctgatg ccatgacagc tgcagttgaa
    18121 gcgacaggta gtcctgtttc agacttcaac aaggggaata tcaaggcacg ttgccgtatg
    18181 attgctcagt atgcccttgc tggttcccat agcggagcgg tcattggaac agaccacgcc
    18241 gcggaaaata tcacaggttt ctttaccaag tttggtgacg gcggtgcgga tattctccct
    18301 ctttaccgcc tcaataaacg ccaaggaaaa cagctcttgc agaaacttgg cgcagagcca
    18361 gccctttatg aaaaaatccc aacggcagac ctagaagaag ataaaccagg cctagctgac
    18421 gaagtcgcac ttggagtcac ctatgcagag attgacgatt acctagaagg caaaacaatc
    18481 agcccagaag ctcaagcgac cattgaaaac tggtggcaca aaggccaaca caaacgccac
    18541 ttacccatca ccgtatttga tgacttttgg gagtaaaaac ctccattgga ggtttttacc
    18601 ctgagcctag aaatgagaaa gtgagagaaa gtccggggga tcttgaaccc cgagtttaga
    18661 aataagaaaa tgaggcagat tcggtaactc gaagagttcg atttcatcgt cttacccctg
    18721 caacgatgac taggtttgaa aaagcttgct agatcgcatt tcaaaccagg cagcgactgc
    18781 gtcaagaaat tagaagacaa actcgttttc tagctgttac tgagttgagt ctttttacta
    18841 cgagcataga aataaggaag tgaggtagca tcatgaaatc tatcggtacg caaatattac
    18901 agacagaacg tttgatttta agaagatttg tggagagtga tgcagaagcc atgtttcaaa
    18961 attgggcttc atccgctgag aatttgacct atgttacctg ggatccccat cctgatgtcg
    19021 aaatcactcg aaactcgatt cgcaattggg ttgcttccta tactaatctc aactattaca
    19081 aatgggccat ttgtctaaaa gaaaacccag agcaagtgat aggagatatc agcatcgtta
    19141 agatagacga ggctgattta agctgtgaaa tcggctatgt gctaggcaag gcttactggg
    19201 gacatggtat gatgacagag gccttgaaag ctgtcttgga cttttgtttt actcaagcag
    19261 gttttcaaaa ggtcagagca cgttatgcca gtctcaaccc agcttcaggt cgtgtcatgg
    19321 aaaaggctgg aatgtcctat ctacaaacca ttgttaatgg tgtagagaga aaaggctatc
    19381 ttgcggatct tatttattat ggtataagta gggaagaatg ttgaattcta ttttctgttt
    19441 ctatcgaagt caactattta ttgtaaatat aataattagc attccaagtt tatttgaaac
    19501 tttaaaatag catattgatt agtacaagac agatgttcta gttccttctt taatctggtt
    19561 tagtattagt taaaaaatcg cttgaagctt gtaactaaga gggagctaat cgactaggtt
    19621 ctccagccga acaggtggta atgtactttt tatagtgtaa tcctagctgt tgttaaattt
    19681 aaaatagaat cctctatcga gttagggaat taaattcaac caattttatt tatgtttttc
    19741 tatcaaatta tctaatatta aaatagtctc attctgatga gaaaactatt ctatttatac
    19801 tgcatagttg tataaggaat gatgaaagat gagtgaaagt tatcaagttg gaatgtttgt
    19861 atctaaatat attagcatgt atttagataa gatgtctgca atcctttata tatgagattg
    19921 attacgatat agttaaagtg ttagttcaat aatcaatata tcattctaag tctattttat
    19981 atataaagta tattgtttaa cgtttgatag aaaagatgct atactagaag taggatgtaa
    20041 tggcaaaatc taatactaat aagcgctatg caatacgtaa actcggaaag atttttggtt
    20101 ctgcggtaat cgggctaact ttatttttag gaggaatctg aatacaagtt ttgttcatgc
    20161 tgctgatggg attcaatatg tcagagatga tactagagat aaagaagagg gaatagagta
    20221 tgatgacgct gacaatgggg atattattgt aaaagtagcg actaaaccta aggtagtaac
    20281 caagaaaatt tcaagtacgc gaattcgtta tgaaaaagat gaaacaaaag accgtagtga
    20341 aaatcctgtt acaattgatg gagaggatgg ctatgtaact acgacaagga cctacgatgt
    20401 taatccagag actggttatg ttaccgaaca ggttactgtt gatagaaaag aagccacgga
    20461 tacagttatc aaagttccag ctaaaagcaa ggttgaagaa gttcttgttc catttgctac
    20521 taaatatgaa gcagacaatg acctttctgc aggacaggag caagagatta ctctaggaaa
    20581 gaatgggaaa acagttacaa cgataactta taatgtagat ggaaagagtg gacaagtaac
    20641 tgagagtact ttaagtcaaa aaaaaagact ctcaaacaag agttgttaaa aaaggaacca
    20701 agccccaagt tcttgtccaa gaaattccaa tcgaaacaaa atatctcgat ggcccaactc
    20761 ttgataaaag tcaagaagta gaagaagtag gagaaattgg taaattactc ttactacaat
    20821 ctatactgta gatgaacgtg atggaacaat tgaagaaact acttctcgtc aaattactaa
    20881 agagatggta aaaagacgta taaggagagg gacgagagaa cctgaaaaag ttgttgttcc
    20941 tgagcaatca tctattcctt cgtatcctgt atctgttaca tctaaccaag gaacagatgt
    21001 agcagtagaa ccagctaaag cagttgctcc aacaacagac tggaaacaag aaaatggtat
    21061 gtggtatttt tataatactg atggttccat ggcaacaggt tgggtacaag ttaatggttc
    21121 atggtactac ctcaacagca acggttctat gaaagtcaat caatggttcc aagttggtgg
    21181 taaatggtat tatgtaaatg catcgggtga gttagcggtc aatacaagta tagatggcta
    21241 tagagtcaat gataatggtg aatgggtgcg ttaacagatt cctccctgcg acaaaattga
    21301 taatagtatg tctgaatata taattatata taaaaagcta tagataaggt catcttatag
    21361 cgactataaa aaagtgaaca agcctagtct tctgtacatt agaattcaga tttgttcact
    21421 ttttgtttaa tactcaatga aaatcaaaga gcaaactaga aaactagtcg caggttgctc
    21481 aaagtactgc tttgaggttg tagatagaac tgacgaagtc agtcacatat ataatccaag
    21541 gtgacgttga cgcggtttga agagattttt gaagagtata agtctttgat tttgagacta
    21601 aggagagtca gggtcaaagt agtgaatgat tctgaaataa ctcataatag tctcttgaga
    21661 ggacagataa gagtaacaaa tatggtgcta ctcatgtgtc ttgcattttg atttacaaac
    21721 agcgaagaaa atataggaag ctgaaataaa atatagatga atcaatttgg agagtcaacg
    21781 caatctatgg caatattttc gaagctaggg ggaagcattt taatttcaat gtactaggcc
    21841 tcttctacag ctagctagag tttcaattgt agatgttctt tgaaataata tcttagcgat
    21901 ttattggtat tagaagattt agagaaattc tttctcaata aataaacatg gcgtcaccaa
    21961 aactgaagaa gcggtagtgt tcttggatgg catggtggta ggcatctaag actaattcac
    22021 ggcctgcaaa ggcagaaacc aacatgacca gagttgattt tggcaggtgg aagttggttg
    22081 agaaggcatc cacgaccttc cactcatacc caggtttgat aaagatattg gtccaaccag
    22141 aatctgcttg gatttgccca tcaaacttgg aaccaatagt ttccaaggtg cggatagaag
    22201 tggttccgac agcgatgaca cgaccaccat tttctttgac agagcgaagg gtggcagcag
    22261 cttcctcaga aagttgatag aactctgagt gcatttcgtg ttcgtccaga ttatccacag
    22321 aaacaggtct aaaggttccg agtccgacat ggagagtcag atagactaga tgaacaccct
    22381 tagcttggat ttctgccagc agttctttgg tgaagtgaag accagcagtc ggtgctgcag
    22441 cagagccgct ttccttggcg tagacggttt gataacgttc acggtcatct aatttttcgt
    22501 ggatataagg tggcagaggc atttctccca gactttccaa gacttctagg aaaattcctt
    22561 ggtattcaaa gcggacaatg cgtcccccgt gggtcaattc ttctgtaacg acagcgctga
    22621 ggcggccatc accaaagctg atacgagtac cgaccttgag gcgtttggca ggtttagcca
    22681 gaacttccca ctcgtctcca ctagtgttct taaggaggag aagttccaca tgacctcctg
    22741 tctccacttt ttgaccatag aggcgggcag ggagaactcg ggtgtcgttc atgacaaggg
    22801 catcaccagg ttccagcata tcaataatag agtggaagtg tttatcttgc atttctcctg
    22861 tctcacggtt gacgatgagg agtttggagg catcacgttt ttcaaggggc gtttgggcaa
    22921 tcaattcctc tggcaagtgg aaatcaaaat cagctgtatt catatatttg ttcattcttt
    22981 ctaagttcta atcctatcca ttataacacg tttcaagttt ggacgctctt tttttagaaa
    23041 ttaaatcgtt ttcacttgac aaaaattggt ctataccata taataaatat agacagaaat
    23101 ggaggatgaa aagatgaaag ttattaaagt tgaaaaccaa gttcaaggtg gaaaagttgc
    23161 ttttgagatt ttgaaggaaa aattggctaa tggagctcaa actctaggac ttgcgacagg
    23221 aagtagccca cttgaatttt acaaggaaat tgttgagagt gaccttgatt tttcaaatct
    23281 aaccagtgtc aaccttgatg agtatgtggg ccttgatggg gacaatccac agtcttatcg
    23341 ttacttcatg caagaaaact tgttcaacca aaaaccattt aaagaaagtt tcttgcctcg
    23401 tggtgttaag gacaatgctg aagctgaagt tgaacgctac aaccaaattt tggctgacca
    23461 tccagttgac ctccaaatct tgggaatcgg tcgcaatggg catatcggct ttaatgagcc
    23521 tggtactcca tttgacagtc aaacgcatct agtagaactt gaccagtcta ctatcgaagc
    23581 caatgcacgc ttctttgcca agattgaaga cgtcccaacc caagctattt caatggggat
    23641 taaaaacatt ttggatgcca agtctattat tctttttgct tacggtgagt cgaaagcaga
    23701 agccattgcc ggaacagtat ctggcccagt gactgagaac ctacctgcaa gtagcctcca
    23761 aaatcaccct gatgtaacca tcatcgcaga tgctgaagcg cttagcttac tcgaaaaata
    23821 aaaagtataa gaaccgcttg ctctttggag tgagtggttt tagacatata aaacttcaac
    23881 ttaactttag gaggacacat gaataaagaa gaatttttaa aaataaaaga agcatataag
    23941 agtgctagaa cggaagaaag aaaaagtata ataggcttca ttacaaaaaa gaaagataag
    24001 gaggggaatt ttctttttac taagtcaaaa gataaaccat ataccacaag aaatcaatat
    24061 tcaggaggcg gaggaaataa aaagtacacc tcgggtagta gattatctag gccatatgat
    24121 ttatcaaatc acatgtggat tgatttgtca tataaaggaa atgacatctt aatctcttta
    24181 cagtcttttg atattgatcc aaatagtaaa gaacttcacg tcttatatga tagaataggc
    24241 atcttatttg aacaatctaa aaaaattcca atttttaaag attgctatac aataactaaa
    24301 gtcagtgatg cttttcttaa aatggaaaca acaaactggg aattaccttt atctaaagca
    24361 gatatggaag agatggtgaa ctatattatt aatcattatg aagaataaaa aacttagttt
    24421 cctcttgaca attattcctt ttacgtgtag aatgaaatag atattgaact tgaagggagt
    24481 gaaaaaaatg tctaaaacag tagtacgtaa gaatgaatct cttgacgacg cacttcgccg
    24541 tttcaaacgt gcggttacta aagctggtac tcttcaagaa acacgcaaac gtgaattcta
    24601 tgaaaaacct tctgtaaaac gtaaacgtaa atcagaagta gctcgtaaac gtaaaaaatt
    24661 ctaattgaaa tgaaaggcta gagaaatcta gtcctttttc ttttaaataa atactccaaa
    24721 gcctgcaaaa atctgaaact tcctcctaca atttgatata atagagagaa gaactcattt
    24781 gaaggaggaa atgatgtcgg ttttagtaaa agaagtgatt gaaaagctta gactagacat
    24841 tgtctatggt gaaccagaat tgcttgaaaa ggaaatcaat atagcggata ttacgcgacc
    24901 tggtcttgaa atgacaggct attttgacta ctatacacca gagcggattc aacttttggg
    24961 gatgaaggag tggtcttatc tgatcagcat gccttccaac agccgttatg aagttttgaa
    25021 aaaaatgttt ctacctgaga caccagcagt cattgttgcc cgtggtttgg tggttccaga
    25081 ggagatgtta aaggctgcta gagaatgtaa gattgctatt ttaaccagcc gtgcagctac
    25141 cagtcgttta tctggagagt tatctagcta tctggattct cgtttggcag aacgtaccag
    25201 tgtgcacggt gtcttgatgg atatttatgg gatgggcgtc ttgattcagg gagatagtgg
    25261 aattggtaag agtgagacag gtcttgagct tgtcaaacgt ggtcaccgtt tggtagccga
    25321 tgaccgtgtc gatatctttg ccaaggatga gattactctc tggggtgaac cagctgaaat
    25381 tttgaaacac ttgattgaaa ttcgtggggt tggtattatc gatgttatga gtctctacgg
    25441 tgcgagtgct gtcaaggatt cttcacaggt tcagcttgct gtctatttgg aaaattacga
    25501 tacgcataag acctttgatc gtcttggaaa caatgcagag gaacttgaag tttctggcgt
    25561 agccattcct cgtattcgta ttccagttaa aacaggtcgt aatatctctg ttgtgattga
    25621 ggcagctgcc atgaattatc gtgccaagga aatgggcttt gatgcgaccc gtttgttcga
    25681 cgaacgactg acaagtctca tcgctcgaaa tgaggtgcaa aatgcttgat ccaattgcta
    25741 ttcaactagg acccctagcc attcgttggt atgccttatg tattgtgaca ggcttgattc
    25801 ttgcggttta tttgaccatg aaagaagcac ctagaaagaa gatcatacca gacgatattt
    25861 tagattttat cttagtagcc tttcccttgg ctattttagg agctcgtctc tactatgtta
    25921 ttttccgatt tgattactat agtcagaatt taggagagat ttttgccatt tggaatggtg
    25981 gtttggccat ttacggtggt ttgataactg gggctcttgt gctctatatc tttgctgacc
    26041 gtaaactcat caatacttgg gattttctag atattgcggc gcctagcgtt atgattgctc
    26101 aaagtttggg gcgttggggt aatttcttta accaagaagc ttatggtgca acagtggata
    26161 atctggatta tctacctggc tttatccgtg accagatgta tattgagggg agctaccgtc
    26221 aaccgacttt cctttatgag tctctatgga atctgcttgg ctttgccttg attctgattt
    26281 ttagacggaa atggaagagt ctcagacgag gtcatatcac ggccttttac ttgatttggt
    26341 atggtttcgg tcgtatggtc atcgaaggta tgcgaacaga tagtctcatg ttcttcggac
    26401 ttcgagtgtc ccaatggctg tcagttgtcc ttatcggtct cggtataatg atcgttattt
    26461 atcaaaatcg aaagaaggcc ccttactata ttacagagga ggaaaactaa atgttagaag
    26521 ttgcatatat tcttgttgcc ttagctttga ttgtcttttt ggtctatctg atcattactg
    26581 tacaaaagct tggtcgtgtc atcgatgaaa cagaaaagac gattaaaacc ttgacttcag
    26641 atgtggatgt gaccttgcat cacaccaatg agttgttggc taaggtcaat gtcttggcag
    26701 atgatatcaa tgtcaaggtg gctacgattg atccactctt cagtgctgtt gcagatttat
    26761 ctctatctgt ttcagacctc aatgaccatg cgcgtgtctt gagcaagaaa gcttcatcag
    26821 ctggttcaaa aacactcaag actggtgcaa gtctgtcagc tcttcgtctt gcaagtaaat
    26881 ttttcaaaaa ataaaaaagg agaatcctta tgggtaaatt atcctcaatc cttttaggaa
    26941 cggtttcagg tgcagctctt gccttgtttt taacaagtga taagggcaaa caagtttgca
    27001 gtcaggctca agattttcta gatgatttga gagaagatcc ggagtatgcc aaggagcaag
    27061 tctgtgaaaa actgacagaa gttaaggagc aggctacaga ttttgttctg aaaacaaaag
    27121 aacaggttga gtcaggtgaa atcactgtgg acagtatact tgctcaagct aaatcctatg
    27181 cttttcaagc gacagaagca tcaaaaaatc aattaaataa tctcaaggaa caatggcaag
    27241 aaaaagccga agctcttgat gactcagaag agattgtgat tcatataaca gaagaataaa
    27301 ccatcaccat ctccggacgg actatgtatc tggggatggt gatttttatc tggaatctag
    27361 tctttgtggt ataataatta ctatgcagaa aaaaccaacg tcagcctatg tgcacatccc
    27421 attttgtacc cagatttgtt attattgtga tttttcaaag gtcttcatca aaaatcagcc
    27481 agtcgacagc tatttagagc atctgctgga agagtttcgt tcttatgata ttgaaaagtt
    27541 gtcaaccctt tatatcggtg gtggaacacc gacagccctg tcggctccgc aactggaggt
    27601 gttactgaat ggcttgacta aaaacttgga tttgtctgtc ttggaagagt tgaccattga
    27661 agccaatcca ggcgatttgg atgcggataa gatagctgtt ttgaaaaatt cggctgtcaa
    27721 tcgtgtttcg ctaggtgtcc agacctttga tgataagatg ttgaaaaaga ttgggcgcag
    27781 tcatttggag aaggatattt atgaaaatat cgatcgcctg aaactggctg gttttgacaa
    27841 catctccatt gatttgattt atgctctgcc tggtcagacc atggagcaag taaaggaaaa
    27901 tgtggctaaa gccattggat tggatattcc ccacatgagt ttgtatagtt tgattttaga
    27961 aaaccatacg gtctttatga accggatgcg acgtgggaaa ttgcctctgc ctaaggagga
    28021 actagaagcg gagatgtttg agtacatcat tgcagagctg gagcgagcgg gttttgagca
    28081 ttatgagatt tctaatttct ccaaacccgg ttttgaaagt cgtcataatc tcatgtactg
    28141 ggacaatgct gaatactatg gtattggtgc aggggcatct ggttatgtca atggagtacg
    28201 ctataaaaat catggtccca ttcgtcatta tctcagtgcg gttgaggaag gcaatgcttg
    28261 tattacagaa gatcacctga gtcaaaagga gcaaatggaa gaagaaatgt tcttgggact
    28321 ccgcaagaaa tccggggttt ccatggcgcg atttgaggaa aaatttggac agtcttttgc
    28381 tggactttat ggagaaattg tcagagattt ggttcaacaa ggcctcatgc agattgaggg
    28441 tgaccacgtt cgcatgacaa agagaggtct ctttttggga gatactgtag cagaacgatt
    28501 tattttggag taggatcatg ggcttaactt atcaaatgaa aatgaaaatt ccttttgata
    28561 tggctgatat gaacggtcat atcaaacttc cagatgtgat tttgctgtca ctgcaagttt
    28621 cagggatgca atcgattgaa ctgggagtta gtgataaggc cattttggaa gactataatc
    28681 tggtctggat tatcgcagaa tatgatattg aggtggttcg tttgcctcgt tttgcggaag
    28741 aaattaccat cgaaacggaa gccttgagct acaatcgact tttttgctac cgtcgcttta
    28801 ctatttataa tgaagcgggg caggagctca tccatatgat ggcgaccttt gttctcatgg
    28861 accgcgacag tcgaaaagtc catgctgttg aacctgagat tgtggctcct taccagtctg
    28921 attttgataa aaaacttatc cgtggaccga agtatgaatc cttggaagag ccgatcagca
    28981 aggattacca tgttcgtttt tacgacttgg atatgaatgg tcatgtcaat aacagtaaat
    29041 acttggactg gatttttgag gtcatgggag cggatttttt gacccactat attcccaaga
    29101 aaatcaacct caagtatgtc aaggaagttc gaccaggtgg ggtgattaca tcggctgttg
    29161 aacggactgg actggaaagc aagcatgaaa ttacaagtga tggggttatc aatgcccaag
    29221 caatcattac ttggcaagaa ataaaaaagg tttagggaga aatagatgaa atataaaggc
    29281 tatttaatcg atttagacgg aaccatttat aaggggaaag accgaatccc tgctggagag
    29341 acttttgttc atgaattgca aaagcgggac attccctatc tctttgtaac caacaataca
    29401 acccgcactc cagagagtgt taaggagatg ttggctcaga attttaatat cgatacgcct
    29461 ctatcgactg tctacacagc gactttggca accatcgact atatgaatga tttggggctt
    29521 gaaaagaccg tctatgtcgt cggagaagca ggactcaagg aagccatcaa ggcggctggt
    29581 tatgtggaag acaaggaaaa ccctgcctac gtggtagttg gtctggattg gcaagtcgac
    29641 tatgaaaaat ttgccacagc aactcttgct attcaaaagg gtgcccattt tatcggaacc
    29701 aatcctgacc tcaacatccc gacggaacgt ggtcttttgc caggtgctgg ctcactgatt
    29761 acgctgcttg aagtagcgac acgagtgaag ccggtttata tcggaaaacc aaatgccatc
    29821 attatggaca aggcggttga gcacttaggt ttggaacgtg aagagttaat catggttggg
    29881 gacaattatt tgactgatat ccgggctggg attgacaatg gcattccaac actcttggtg
    29941 acgacaggtt ttaccaaggc agaagaagta gctggcctgc caatcgcacc gacacatgtg
    30001 gtttctagcc ttgcggagtg ggattttgat gaaaactaaa ttgacctttt ggggctctat
    30061 gctctttctc ctctccctct caatccttct gaccatttat ctggcttgga ttttctatcc
    30121 tatggagatt cagtggctaa acttaacgaa tcgagtctat ctaaaaccag aaaccattca
    30181 atacaatttt catatcttga tgaattatct gaccaatcct tttagtcagg tcttacagat
    30241 gcctgatttt cgttcgtcag cagctggtct gcaccatttc gcagtggtca agaatctctt
    30301 tcatttggtt cagctagtag ctctagtgac actgccaagt ttctatgtct ttgtcaatag
    30361 gattgtgaaa aaggactttt tgtctcttta tcgaaaaagt ctcctgactc tagtagtctt
    30421 acctgtgatg attggacttg ggggagtttt gattggtttt gaccaattct ttactctttt
    30481 ccatcaaatt ctctttgtgg gagatgatac ctggcttttt gatccagcca aggatcctgt
    30541 tattatgatt ttgccagaga ccttctttct tcatgccttc ctcctctttt ttgccctcta
    30601 tgaaagcttc tttgggtatc tgtgtctgaa aagtcgtagg aagtgaaatg aaagatgttt
    30661 ttaatttgca tatataaaaa tatatatcgt ttaaaaccat cgttaagagt gaattaacca
    30721 aatccaattg tgtcaatcgt tcgcaaacag cctatttttc ttgaaaaaat aggctttttt
    30781 tctaaaaatc cctagtcaag cgccttattt ttttgtataa tagaagtagc aaagtataga
    30841 taagaagaga aaagcatgat tacactattt ctatcaccga gctgtacatc atgtcgtaag
    30901 gctaaggcct ggttagaaaa acataaggtt ccctttgtgg aacacaatat tatgaccagt
    30961 cctttaacaa gaaaagaatt gcaacacatc ctttccttga ccgaaaatgg tactgatgac
    31021 atcatttcaa ctcgttcaaa aatttttcaa aaattgaata ttgatgtaga gagtatttcg
    31081 gtatcggaat tgcttcattt gattgagcag tatcctagtc ttttgcgtcg tccaattatt
    31141 attgatgcca agcgtatgca aatcggtttt aatgaagatg agattcgtgc ttttctccct
    31201 cgtagttatc gtaagcaaga actaaaagaa gcaagaatga gagctggtat tagttaatga
    31261 acaaacagta tagttaccca ctagatttgt cgtggagcac tgaagaactt gcttcagtgc
    31321 tttctttttt taatgatgtt gaagctgcct atgaaggcaa agtagaggct aaaaagttac
    31381 tggactccta taagggattc aaagcggtcg tgccaagcaa gagcgaagag aaacgtttgg
    31441 gacgagaatt tgaaacggtt agtggctatt cactttaccg agcagttcag gctgccaaag
    31501 aaaaagggga aggaaagatt tctcttggaa agtaaatttg aatttgctaa agagcttgtt
    31561 aagaaagcag gccagtacat tcttgaccat atgcaggaag acttgcgtgt tgaaaccaag
    31621 tcctcttcaa cagatttggt gaccagactg gacaaagaag ttcaggaact cttggttggt
    31681 gagattttgt cccgttatcc tgaggataag atttgtgctg aagaaggttg tctgcgagcc
    31741 tcggttcaag agggcaaggt ttgggtcatt gatcccattg atggtaccaa taattttgta
    31801 gcccagcagg aagattttgc tgttatgatg gcttattttg aaaatggtca gggacagttt
    31861 ggtctgattt atgatgtggt caaaggggat tgttaccacg gtggtgggga atttccagtt
    31921 tgtctaaatg ataggcccct agctcctttt aaaactaaac cacttggaga ttttctcatt
    31981 gcagggaata gtggtatgct ggaaaccaat gaatgggggc tggctgattt gagccgatcg
    32041 gttcttggtg ttcgtgtcta tggaagtgcg gccattagtt ttgccaagat tttgtcaggg
    32101 cgtttgttga cctatctcac ttatctgcaa ccatgggatt atgccgcagc tagtatttta
    32161 ggggaaagtc tgggctatcg ggttgtgacc ctttttggtg aagctcctga ttttcaaacc
    32221 agacagccgg tcatgatggt gcctcttgag atgcaggagg aaattcagtc ctatatttac
    32281 gaaaggaaaa gaacttaaat gcaatttcca gaaggatttg ttgaaaaata taaagagata
    32341 ctaggagatg aggcaagaga ttttcttgcc tcttttgagg aggaagcggt ttcggccttt
    32401 cgggtcaatc ccttaaaaga agagcaactt tccttttctg atgccattac tcaaacccct
    32461 tggggccact atgggaaggt ttcagggaaa tcgcctgagc atgctacagg tttagtttat
    32521 tcgcaagaac ctgctgctca aatggtggct caagtagccc aacccagtcc tggtatgaag
    32581 gtcttggact tggctgctgc accggggggc aaatcaactc aactggcagc ctatctagca
    32641 ggtgaggggc tacttgtttc caatgaaatt tcaagcaaac gggctaagat tttggttgaa
    32701 aacatggagc gttttggagc gacaaatgtc gtggtgacca atgaatctgc cgaccgcttg
    32761 gtcaaggtct ttaaaggcta ttttgactta atcgttcttg atgccccttg ctctggtgaa
    32821 ggaatgtttc gtaagcaacc tgatgctatg gactattgga gcttagatta tccgagtcaa
    32881 tgtgctagct tgcaaagaga aattctggag gatgcagtga ccatgttagc tgaaggtggt
    32941 cgtctggttt attcgacctg tacctgggca cccgaggaaa acgaagagat tgtcaattgg
    33001 ttgctggaag agtatgattt tgacttgttg ccagtagagc atatcaatgg aatggtagct
    33061 ggtattgacc tgccagaaac ggctcggatg taccctcatc agtttaaggg agagggtcag
    33121 tttgttgccc atctacagtt taagggtaac aatccagctc ctaaatttaa ggcaagtaag
    33181 agtaacctca gccgtgaaca agttgccttg tggcaggaat ttgcccaaaa ccatttgaag
    33241 gtcaatctac cgggtatctt gcagactttt ggagaccagc tttatctctt gccagaactt
    33301 ttgccagatt tagggaagct caagattgct cgcaatggac tgcatctggg cacttttaag
    33361 aagaaacgct ttgagcccag tttcgctctt ggtttagcct tgaaaccgag tcaggtcgaa
    33421 cagtcggttg aaattggcca agaagcgttt gtcaagtatg cggctggaga aaccgttcag
    33481 ctggcagaaa gtctgccaaa tggttggtac caagttttgg ttaaaggcaa tggcttgggc
    33541 tttgcaaagg ttactggaaa tgttttgaaa aattattttc caaaaggcct cagattcaaa
    33601 tgaaaatgct agtcaaatat cttattctat gttatagtga aagtatggat ttttttagta
    33661 ggatgattct tgatatcttg attgccatca catgtagttt tactactcga tgaaaatcaa
    33721 agagcaaact aggaagctag ccatagatag ctcaaaacac tggtttgaag agattttcaa
    33781 agagtacaag aagtttagtt attagcgttc ttaccgcttg taaactagat ttctcataaa
    33841 atagaatctt ttccttttag ttgtaaacta gtctgggaga gtagagaggt ttgagatacc
    33901 tttctagctt ttggattatc atctgaggag agtaatttcc cttgcattaa aaaggggaaa
    33961 aagagacacg aaatgattat aatgggtgac aatgggggaa gggatagaca agagatttta
    34021 tccacatatg aaaaaaggag gttaggaaag agtaatatag cctatattat ataaataatc
    34081 aattgcgcag aaatttggta agaattcatg cgtcaactca taaagaacta cttaaaaaat
    34141 tcacagtatt cataattatt ttcgaggaga aaaacagtga aaaaaagaaa aaagcttgct
    34201 ctgtctctta tcgctttttg gctgacggct tgtttagtag gctgtgctag ctggattgat
    34261 cgtggagaat ccataacggc tgttggctca actgccttgc aacccttggt tgaagtagcg
    34321 gcagatgaat ttggcacgat ccatgttgga aaaacggtca atgtccaagg gggaggttct
    34381 ggtacaggct tgtcccaggt tcagtctggg gcagttgata taggaaactc agatgtattt
    34441 gctgaggaaa aagacggaat tgatgcttct gctcttgttg accacaaggt cgcggtagct
    34501 ggcttggctc tgattgtcaa taaggaggtt gatgttgata acctaacgac agagcaactt
    34561 cgtcaaatct tcataggtga ggtaaccaat tggaaagagg ttggtggtaa ggacttaccc
    34621 atctctgtta tcaatcgggc agccggctct ggttctcgtg ctacctttga tactgtcatt
    34681 atggaaggtc agtctgccat gcaaagtcag gagcaggatt caaatggagc ggtaaaatca
    34741 atcgtatcaa aaagtccagg agctatctct tatttatctc ttacctatat agatgattcg
    34801 gtcaaaagca tgaagttgaa tggctatgac ttaagtccag aaaatataag tagcaataat
    34861 tggcccttgt ggtcttatga gcatatgtat acattggggc agcccaatga gttggctgca
    34921 gaatttctca attttgttct ctcggatgag acccaagaag ggattgtcaa aggattgaag
    34981 tatattccga ttaaggaaat gaaggttgaa aaagatgctg ccggaactgt gacagtgttg
    35041 gaagggagac aataatgaat caagaagaat tagctaagaa aatgttgctt ccatcaaaga
    35101 attctcgtct ggagaaatta ggaaaaggtt tgacctttgc ctgtctttct ttgatagtca
    35161 tccttgtggc catgattttg gttttcgtag cgcaaaaagg cttgtcgacc ttctttgtca
    35221 atggtgtgaa tatctttgac tttcttttgg gaggaacttg gaatccttct agtaaagaat
    35281 ttggtgccct tcctatgatt ttgggttcct ttatcgttac cattctctca gcccttatcg
    35341 caacaccctt tgctattggt gcagcagttt ttatgaccga agtatcacca aaaggggcga
    35401 agattttgca accagctatt gaactcctgg ttgggattcc ttcagtagtg tatggattta
    35461 ttggcttgca agtcgtcgtt ccctttgttc gcagtgtctt tggtgggact ggttttggga
    35521 ttttgtcagg gatttccgtc ctctttgtca tgattttgcc gaccgtaacc tttatgacaa
    35581 cggatagctt gcgtgcggtt cctcgttatt atcgtgaagc cagtttcgct atgggagcca
    35641 ctcgctggca gactatctgg cgtgtgatct tgaaggcggc ccgttctggt attttcactg
    35701 cagtggtctt tgggatggcg cgtgcctttg gtgaggcttt agctatccag atggttgtcg
    35761 gaaactcagc tgttatccca acttccttga ccacaccagc tgcaacttta acttctatat
    35821 taactatggg aattgggaac actgtcatgg gaactgtaaa taataatgtt ctctggtcac
    35881 tggccttggt actgctcttg atgagtttag tttttaacag tgtgattaaa ttgattacga
    35941 aagaaagagg aaagaaaaat tatgcgcgct aagaaattag ataaacttgc aacagctgtc
    36001 ctctatacga ttgctagcat cattgtgaca atcttggctt ccttgattct ctatatcttg
    36061 gttcggggct tgccccatat ctcttggtct ttcttgactg gaaggtcttc tgcttttcaa
    36121 gcaggtggtg ggattggcat tcagctttac aattcctttt tcctattggt cattaccttg
    36181 attatttctg tacctctttc tatgggagct gggatttact tggctgaata tgctaaaaaa
    36241 ggtcctgtta ccaactttgt gcggacttgt attgaaatct tgtcctcttt accatcagtg
    36301 gtggtgggtc tctttggtta cttgatcttt gtagtccagt ttgagtatgg attttcaatc
    36361 atttcaggtg ccttggcctt gacagtcttt aacttgcctc agatgacgcg taatgtagag
    36421 gatagtttga aacacgttca ccatacccaa cgtgaggctg gtctggctct tgggatttct
    36481 cgctgggaga cagtggttca tgttgttatt ccagaagcgc ttccaggtat tgtaacgggt
    36541 gtcgtcttgg catctggtcg tatctttggc gaagctgcag ctctgatcta tacagcaggg
    36601 caatcggcgc cagctcttga ctggtctaac tggaatatcc tcagtgtgac tagccccatc
    36661 tctatcttcc gtcaagcaga aaccttggct gtccatatct ggaaagtcaa tagtgaaggc
    36721 actattccag atggaaccat tgtatcagca ggttctgccg ctgtgctcct gatctttatc
    36781 ctgattttta actttggagc tcgtaagttc ggaagctatc tacacaagaa attaaccgct
    36841 gcctaaagga gaagccatgt caacatataa ctgggatgag aagcatatcc ttacctttcc
    36901 tgaagaaaaa gtagcccttt ctactaagga tgtccatgtt tactatggta aaaatgaatc
    36961 cattaagggg attgatatgc aatttgaaag aaataaaatt acagctttga ttggtccgtc
    37021 gggatcgggg aaatctacct acttacgcag tctcaatcgc atgaatgata ccattgatat
    37081 tgctaaagta actgggcaga ttctctatcg tggaattgat gtcaaccgtc cagaaatcaa
    37141 cgtttatgaa atgcgtaaac acattggaat ggtttttcaa cgccccaatc catttgctaa
    37201 gtcaatttac cgtaatatta cctttgcgca tgaacgtgct ggagttaagg ataagcaagt
    37261 cctagatgaa atcgtagaaa cctcccttcg tcaggctgcc ctctgggatc aggttaaaga
    37321 cgatctccac aagtcagcct tgaccttatc aggtggtcag caacaacgtc tctgtatcgc
    37381 tcgtgccatc tctgttaagc cagatatcct cttaatggat gagccagctt cagccttgga
    37441 tccgattgcg accatgcaac tagaagagac catgtttgag ctcaagaaag actttaccat
    37501 catcattgta acgcataata tgcagcaggc tgctcgtgca agtgactata caggcttctt
    37561 ttacttgggt gatttgattg agtatgacaa gactgcaact attttccaaa atgccaagct
    37621 acagtccacc aatgactatg tatctggtca ctttggttag aaaggaaacc gtatgacaga
    37681 tgcgatttta caggtatcag acctgtccgt ttattataat aaaaagaagg ctttgaatag
    37741 tgtttcccta tctttccaac ctaaggaaat tacagccttg attggtccat ctggatcagg
    37801 gaagtcaacc ctcctcaagt ctctcaaccg catgggagat ctcaatccag aggtgaccac
    37861 aactggatcc gtggtgtaca atggtcacaa catctacagt ccgcgtacag atacggttga
    37921 attacgtaag gaaatcggaa tggttttcca acaacctaat cctttcccta tgactatcta
    37981 tgagaatgtt gtctacgggc ttcgtatcaa tggaattaag gataagcagg ttctggatga
    38041 agccgtagaa aaagccttgc aaggtgcctc tatctgggat gaggtcaagg atcgtctata
    38101 tgattcagct attggattgt caggtggtca acagcagcgt gtctgcgtgg cccgtgtctt
    38161 ggcaactagt cctaaaatca tcctcttgga tgagccaact tcggctttgg atccgatttc
    38221 agctggtaaa attgaggaaa ccttgtatgg tctaaaagac aagtacacca tgcttctggt
    38281 aacccgttcc atgcagcaag cttcacgtat ctctgataag acaggatttt tcctagatgg
    38341 agatttgatt gaatttaatg ataccaagca gatgttcctt gatccccaac acaaggaaac
    38401 ggaagactat attacaggaa aatttggata aggagatgaa agatgttacg atctcaattt
    38461 gaagaagatt tagagaaatt acataaccag ttctacgcta tgggacaaga agtgctctca
    38521 caaatcaatc gtacggtacg tgcttttgtc acgcatgacc gtgacctggc aaaagaggtc
    38581 atcgaagatg atgcagaagt aaatgaatac gaagtgaaac tggaaaagaa atcatttgaa
    38641 atgatcgcac tccaacaacc agtctctcaa gatttgcgta cagtcttgac tgtccttaag
    38701 gctgtatcag atgtggagcg tatgggggat cacgctgtag ccattgccca ggcaaccatc
    38761 cgtatgaagg gggaagaacg catcccagct gtagaggaag aaattaaaaa aatgggacgt
    38821 gaagttaaaa gcgttgttga agcagcactt gatctttatc ttaatggttc tgttgacgac
    38881 gcataccggg tggcctccat ggatgagcaa attaaccact attttgaaac tatccgtgac
    38941 cttgcgactg aagagattaa gaaaaatcca gaagccattg ttacgggtcg tgattatttc
    39001 caagttattt cctacttgga gcgtatcggt gactatgcta aaaatatctg tgaatgggtt
    39061 gtctactttg aaacaggtaa gattgtcgaa ctataaaata gtttaattct gtataaaaag
    39121 gagcttgaaa tcaactgatg gctccttttt ttgaacgaaa acatattttt gagataaaaa
    39181 tttaaaaaac acttgacaag taacttggat atcgttataa ttatacaaaa ttaacagaga
    39241 ggttgtttat ttatgaaatc aaaaaaatgg atatttgttt tatgtaattt tcttgcaagt
    39301 ttcttcttag tagcttgcca gtcaggttct aatggttctc agtcagctgt tgaggccatt
    39361 aagcaaaagg ggaaattagt tgtggcaacc agtcctgact atgcaccctt tgaatttcaa
    39421 tcattggttg atggaaagaa ccaggtagtc ggtgcagaca tcgacatggc tcaggctatc
    39481 gctgatgaac ttggggttaa gttggaaatc tcaagcatga gttttgacaa tgttttgacc
    39541 agtcttcaaa ctggtaaggc tgacctagca gttgcaggaa ttagtgctac tgacgagaga
    39601 aaagaagtct ttgatttttc aatcccatac tatgaaaaca agattagttt cttggttcgt
    39661 aaggctgatg tggaaaaata caaggattta actagcctag aaagtgctaa tattgcagcc
    39721 caaaaaggga ctgttccaga atcaatggtc aaggaacaat tgccaaaagc tcaattaact
    39781 tccctaacta atatgggtga agcagtcaat gaattgcagg ctggaaaagt agatgctgtt
    39841 catatggatg agcctgttgc acttagttat gctgctaaaa acgctggctt agctgtcgca
    39901 actgtcagct tgaagatgaa ggacggcgac gccaatgccg ttgctcttag aaaaaatagt
    39961 gatgatttga aagaagtggt agacaaggtc atccaaaaac ttaagaatga aggaacttac
    40021 caaagctatc ttgaaaaagc agcaagtcta actgaagttg aagaataaga aaaagcagag
    40081 ttggatgtca ttccaattct gcttttaaat agtttaaaac attttccaga ttgtctaggg
    40141 acaccttggc aaattgataa ggacaggtgc ttaaataggc ctcttcaaag aagtccaagc
    40201 ccagttgact gtgtttgaga ctggcgattt taggatactg tctcaggtct agcaataaac
    40261 catcgtgtag gggataatga ggaaggggac aaggtgtttt agttatcctt tcctcgattt
    40321 gtttttggta agattcatga ttggtcaagc gagccaaacg atttttttca aacaattgac
    40381 tgtcaatata gagtgacagg gccttttgca taatgaggtt gctgtcgtag tctaggatat
    40441 ttttgtaggc cacaaatgct tctttgatag catttggaag aatgagtgct gtaatacgaa
    40501 gggcaggaaa aaggctggtc gagaaggact tgatataaat gacatgctcc tctgtatcaa
    40561 gatagtggaa ggtttggccc ttcttggagt ccaaatcacc cagataatcg tcctctacga
    40621 tatagacatc atacttggca gctaagttaa gaatagatcg tttgtcttgc tcagaatagg
    40681 aatgtcccag aggatagtga aatctaggaa tggtgtagaa aaatttaatt tttcctgttt
    40741 tgaagtggcc ttccagctcc tccaagtcaa tcccatcaat gcctcgttca atcgtttgat
    40801 agtccagccc ctgtgcaatc aagaggcgat tcatccgatg gtaggttggc tgttccacca
    40861 agatttcctt ggcttgtcta ggaaaggata tttgagagag gataaacaag gcttgttggg
    40921 ttccagaagt cagtactagt tggttagcct tgcagtagag agcttgctca aataggagtt
    40981 tgtgaatgga ctgtcttagg tcttctaatc cttcttgatt gtcatagtag ttgaagaggt
    41041 agttttctcg tccaatcaag gtttcattga cacagagtcg gaaatcgtca taggcactgg
    41101 catgttcgtc ggtaacctcg atttctaggt cttgatgttg cccttgttct aatacatagt
    41161 agccactctg aggcttggca tagaggtatt gttcgtgccg taattccagc agggctcgtt
    41221 gaatggtgtc cttgctgcag tgaaagtcaa ggctcagttg acggatagaa ggcaggcgac
    41281 tacccgtcgg aaatcgttca gactcgatac catttttcag ataggaaacg acctctttgt
    41341 acttgctttg tttcttcatt ccagacctcc cttgattttg ttacattgta cccttttttt
    41401 tccttcttgg caatgtctag agcgtttctc tcgttcacat ctaggggcaa atgtggtata
    41461 cttaggagta agatttatag aataacagac aagaaagtga atggataaga acgtgcagga
    41521 accagtgaaa ttatttcaat acaatactct tggagccttg atggctggcc tttatggtgg
    41581 tactatgaca gtaggagaat tgctagaaca tggtgacctt ggtttgggaa ccttggattc
    41641 cattgatggg gaattgattg tcttggatgg caaggcttat caggccaaag ggtcaggaga
    41701 ccagccagaa attgtggaag tgtcaccaga tgcccttatt ccttacgctg cagtggtacc
    41761 gcatcaggca gaggtcattt tccgccagcg ctttgagatg acagacaagg aattgaaaga
    41821 acgaattgag tcttattatg atggggaaaa tcttttccgc tctatcaaga ttcgggggga
    41881 attttcacat atgcatgtgc gtatgattcc taagtcaaca cccgatacca agtttgctga
    41941 tgtcgcaacc catcaaccgg aatatagtcg tgacaatgtt gcggggacta ttgttggttt
    42001 ctggacgcct gagattttcc atggggtcag tgtggcaggc taccatctgc acttcatatc
    42061 agatgatttg accttcggtg gacatgtcat ggattttgtc atcaaggaag gcattatcga
    42121 ggtgggagca gttgaccagt tggaccaacg tttcccagtc caagaccgtc aatacttgtt
    42181 tgctaagttc aatgttgacg agatgaaaaa agatattgaa aaggcagaat aggagaagaa
    42241 aatgaccatt catatcatta ttaccatgtt gctgttgcta gcttttctga taggaagcat
    42301 ttggtttgcc aaaaagaaat accagattaa tctagctgtc ttgggcttgg gtgcagtcgc
    42361 tttctttgtc tcttcgcaga ttttggaaaa actggtgcat atcttgattt tgcatcctca
    42421 aaaagacggt agtattgccc tcttgcaaga tcatccgctt atctatatta tctatggcct
    42481 agccatggca gcattttttg aggaaacggc tcgtcttgtt ttcttcaaat ggttggagaa
    42541 aaagagaagt ttggaaaagg cagatgcctt ggcctatggc ctagggcatg gtggcttgga
    42601 gttgattttt ctaggcctta ttagtttact caatctttac atcgttcttt cggcagttca
    42661 aactcagaat ccacaggtta tgcaattact gtctgaaaat atgttaaaaa ccattcagtc
    42721 actttcggtc tggcagattt atttgcttgg ttttgagcga atcttggcgc ttggtttcca
    42781 attacttttg acagtttggg tttaccaagc tgttcgccag aagaaatgga tttatctcct
    42841 agcagcctat ggcttgcatg ccttctttga tctggcacca tctcttttcc aagtaggctg
    42901 gttgacaaat ccagtcttgg ttgaagtgat tctagcactg gagctcgttc tggtcgccta
    42961 tggaaccaag gaaatctttt gtaaaaaatc ataaaaaggg gggaacctct ttttcttatg
    43021 caaaatccaa acaaggtatt tttatggtcg tcaaatgtct ctaaaaatgg tataatggaa
    43081 tgaattttgt aaaaggaaga gtgacatgtc tgtaagagaa aaaatgcttg aaatcttaga
    43141 aggaattgat atccgtttta aggaaccctt gcatagctat agttatacaa aagtaggtgg
    43201 agaggctgat tatttggtct ttccacgaaa tcgttttgag ttggctcgcg ttgtgaaatt
    43261 tgccaaccaa gaaaatatcc cttggatggt tcttggcaat gcaagcaata tcatcgttcg
    43321 tgatggtggg attcgtggat ttgtcatctt gtgtgacaag ctcaataacg tttctgttga
    43381 tggctatacc attgaagcag aagctggggc taacttgatt gaaacaactc gcattgccct
    43441 ccgtcatagt ttaactggct ttgagtttgc ttgtggtatt ccaggaagcg ttggcggtgc
    43501 tgtctttatg aatgcgggtg cctatggtgg cgagattgct cacatcttgc agtcttgtaa
    43561 ggtcttgacc aaggatggag aaatcgaaac cctgtctgct aaagacttgg cttttggtta
    43621 ccgccattca gctattcagg agtctggtgc agttgtcttg tcagttaaat ttgccctagc
    43681 tccaggaacc catcaggtta tcaagcagga aatggaccgc ttgacgcacc tacgtgaact
    43741 caagcaacct ttggaatacc catcttgtgg ctcggtcttt aagcgtccag tcgggcattt
    43801 tgcaggtcag ttaatttcag aagctggctt gaaaggctat cgtatcggtg gcgtagaagt
    43861 gtcagaaaag catgcaggat ttatgatcaa tgtcgcagat ggaacggcca aagactacga
    43921 ggacttgatc caatcggtta tcgaaaaagt caaggaacac tcaggtatta cgcttgaaag
    43981 agaagtccgg atcttgggtg aaagcctatc ggtagcgaag atgtatgcag gtggttttac
    44041 tccctgcaag aggtagtggg gacctgacag agccccgatc ggttaatcta tgaaaaagaa
    44101 ggaatttatg ccaattgaaa aaaccaatta tcgaattcaa aaacgtctct aaagtttttg
    44161 aagacagcaa caccaaggtt ctcaaagaca tcaactttga gttggaagaa gggaaattct
    44221 acacccttct aggtgcatct ggttcgggga aatcaactat cctaaacatt attgcaggtt
    44281 tactggatgc gacgacagga gatatcatgc tagacggtgt tcgtatcaat gatattccaa
    44341 ccaacaagcg cgacgtacat accgtcttcc aatcctatgc cttgttccca catatgaatg
    44401 tgtttgaaaa tgttgccttt ccacttcgct tgcgtaaaat tgataagaaa gaaattgagc
    44461 agcgtgtagc ggaagttctc aagatggttc agttggaagg ttatgaaaaa cgttccatcc
    44521 gcaaactttc tggaggacaa cgtcagcgtg tggccatcgc ccgtgctatc atcaaccaac
    44581 cccgtgtggt cttgttggac gagcctttat cagcgctgga cttgaaattg agaacagaca
    44641 tgcagtacga attgcgtgaa ttacaacaac gattgggcat tacctttgtc tttgtcactc
    44701 acgatcagga agaagctctt gccatgagtg actggatttt cgttatgaat gatggcgaga
    44761 ttgtccagtc tggaacccct gtggacatct acgatgagcc aatcaaccac tttgttgcca
    44821 cctttatcgg ggagtcaaac atcttgccag gtaccatgat tgaggactac ttggtcgaat
    44881 ttaacggcaa acgctttgaa gcggttgatg gtgggatgaa gccaaatgaa cctgttgagg
    44941 tcgttattcg tccagaggac ttgcgcatta cccttcctga agaaggcaag ctccaagtta
    45001 aggtcgatac ccagctcttc cgtggggtgc attatgaaat tatcgcctat gacgaacttg
    45061 gaaatgaatg gatgatccac tcaacccgta aggccatcgt gggtgaggaa atcggtctgg
    45121 actttgaacc agaagacatc cacatcatgc gtctcaatga aaccgaagaa gagttcgatg
    45181 ctcgtatcga agaatacgtg gaaatcgaag agcaagaagc aggtctgatc aatgcgatcg
    45241 aggaggaaag agatgaagaa aacaagctct aaactctttg tagtgcccta catgctttgg
    45301 attgccctct ttgtattggc acccttggtc ttgattttcg gacaatcctt tttcaacatt
    45361 gaaggccagt ttagtttaga aaattataaa tcttactttg cgtcacaaaa cttgacctac
    45421 ctcaaaatga gtttcaactc agtgctttat gcagggattg tgacctttgt aaccttgctt
    45481 atcagctatc caacagccct ctttttgacc cgtctcaagc accgtcaact ctggctcatg
    45541 ctgattatcc ttcctacctg gatcaatttg ctccttaaag cctatgcttt tatcgggatt
    45601 tttggtcaaa atggctctat taaccaattc ttggaattta tcggaattgg ttcacaacag
    45661 ttgcttttta ccgatttttc ctttatcttt gtcgcaagct acatcgagct cccctttatg
    45721 attttgccga ttttcaatgt cttagacgat atggataata atctcatcaa tgctagttac
    45781 gaccttggtg caactaagtg ggagaccttc cgtcatgtca tcttccctct atctatgaac
    45841 ggtgtgcgaa gtggggttca gtcggtcttt atcccaagtt tgagtctctt catgctgacc
    45901 cgtttgattg gtgggaaccg cgttatcacc ttggggacgg ctattgagca gaattttcta
    45961 accaatgaca actatggtat gggttcaact atcggtgtga ttctcatcct gaccatgttc
    46021 atcaccatgt gggtgactaa ggaaaggaga gaacgatgaa aaaatttgcc aacctttatc
    46081 tgggactggt ctttctggtc ctctacctgc ctatctttta cttgattggc tatgccttta
    46141 atgctggtga tgatatgaat agctttacag gttttagctg gactcacttt gaaaccatgt
    46201 ttggagatgg gagactcatg ctgattttgg ctcagacatt tttcttggcc ttcctatcag
    46261 ccttgatagc gaccattatc gggacttttg gtgccattta catctaccag tctcgtaaga
    46321 aataccaaga agcctttcta tcactcaata atatcctcat ggttgcgcct gacgttatga
    46381 ttggtgctag cttcttgatt ctctttaccc aactcaagtt ttcacttggc tttttgaccg
    46441 ttctatctag tcatgtggcc ttctccattc ctatcgtggt cttgatggtc ttgcctcgac
    46501 tcaaggaaat gaatggcgac atgattcatg cggcctatga cttgggagct agtcaatttc
    46561 agatgtttaa ggaaatcatg cttccttacc tgactccgtc tatcattgct ggttatttca
    46621 tggccttcac ctattcgtta gatgactttg ccgtgacctt ctttgtaaca ggaaatggct
    46681 tttcaaccct atcagtcgag atttactctc gtgctcgcaa ggggatttcg ctagaaatca
    46741 atgccctttc tgctctagtc tttctcttta gtattatcct agttgtaggt tattacttta
    46801 tctctcgtga gaaggaggag caagcatgaa aaaaatctat tcatttttag caggaattgc
    46861 agcgattatc cttgtcttgt ggggaattgc gactcattta gatagtaaaa tcaatagtcg
    46921 agatagtcaa aaattggtta tctataactg gggagactat atcgatcctg aactcttgac
    46981 tcagtttaca gaagaaacag gaattcaagt tcagtacgag gcttttgact ccaacgaagc
    47041 catgtacact aagataaagc agggtggaac gacctacgat attgccattc caagtgaata
    47101 catgattaac aagatgaagg acgaagacct cttggttccg cttgattatt caaaaattga
    47161 aggaatcgaa aatatcggac cagagtttct caaccagtcc tttgacccag gtaataaatt
    47221 ctccatccct tacttctggg gaaccttagg aattgtctac aacgaaacca tggtagatga
    47281 agcgcctgag cattgggatg acctttggaa gctggagtat aagaattcta tcatgctttt
    47341 tgatggggcg cgtgaggtgc tgggactagg actcaattcc ctcggctaca gcctcaactc
    47401 caaggatccg cagcagttgg aagagacagt ggataagctc tacaaactga ctccaaatat
    47461 caaggctatc gttgcggacg agatgaaggg ctacatgatt cagaataatg ttgcaatcgg
    47521 cgtgaccttc tctggtgaag ccagccaaat gttagaaaaa aatgaaaatc tacgttatgt
    47581 ggtaccgaca gaggccagca atctttggtt tgacaatatg gtcattccca aaacagttaa
    47641 aaatcaagac tcagcctatg cctttatcaa ctttatgttg aaacctgaaa atgctctcca
    47701 aaatgcggag tatgtcggct attcaacacc aaacctacca gcgaaggaat tgctcccaga
    47761 ggaaacaaag gaagataagg ccttctatcc cgatgttgaa accatgaaac acctagaagt
    47821 ttatgagaaa tttgaccata aatggacagg gaaatatagc gacctcttcc tacagtttaa
    47881 aatgtatcgg aagtaggaga taaacgtaag aagacgaatc agtcaagctg gttcgttttt
    47941 aaggaataga agtcagtttt tagagcccta tctttttcta ttctagttgt ttatttgttt
    48001 atttgcttat ttgcttgcct agtagtatac taagcctata ctcttcaaac cacgtcagcg
    48061 ttgccttgcc gtactcaagt acagcttgaa gctagcttcc tagtttgctt tttgattttt
    48121 attgagtatt aaccttacag aaagcggcaa caaataatga aaatgtctac ttttttcaaa
    48181 aaaagtttct ggccaacctt tatgattgtt aaccaaactg ctatactatt ccatttaaat
    48241 gatggcttgg atcgacaata cctaacaact gagtccatat attgggtgat aggcaccttt
    48301 atatttggaa atattctagt agctgtgttt agtaatatga aaatttggga taaaaagaaa
    48361 aatggcagta agaaaaaata tatcctgaaa aagtaatcag agatgtaggg aattggtcta
    48421 attcaacgga gatcatttcc agttgacgca agcttaaaaa aacgttataa taagaaagtt
    48481 gagaattgat tttcacttgt cttagtccag agaaatggcg gtgctgcgag ccatctaagc
    48541 taggaagtca tgctactcaa tcatacaatt gcataagaac aagagaatga caagttcatt
    48601 gaatgaaggt ggtaccgcgg tttttcgccc ttcgtgatat gagcttgtct tttgattttt
    48661 ggaggtgttg atgaaaacat ttcttgtcaa acaaaagttt cgtcttggag gcgaacgctt
    48721 cgctatcaag gatgacaggg gagaaattgc ctatcaggtg gagggatcat tttttaagat
    48781 tcccaaaact tttaccatct atgatgcggc tggtgaacaa gtcagtcaga tcagtaaaga
    48841 aatcttgacc ttgcttcctc gttttgagat tcagcttcgg gatggctcga gttttgtcat
    48901 tcgtaagaag ttgaccttct ggcgagataa gtatgagttt gataatctag gtcttcgtat
    48961 cgagggcaat atctgggatt tgaatttcaa attgctggat gatcgcgatc agttgattgc
    49021 ggaaattaag aaggaactct tccatctgac ctctacctat accgtaacgg ttcttgaaga
    49081 cgcttatgca gacctagtca tttccctctg tgtcgcgatt gactatgtgg aaatgctgga
    49141 aagccaatca cattaaacaa gtgaataagg agacaatatg aaacaactat ctagtgcaca
    49201 agtacgccaa atgtggcttg atttctgggc gaccaaaggt cactcagtag aaccatcagt
    49261 aagtttggtt cctgtaaatg acccaactct tttgtggatc aactctgggg tagcaaccct
    49321 taagaaatac tttgacggga ccattatccc tgaaaatcca cgtattacca atgcccaaaa
    49381 ggctatccgt accaacgaca tcgaaaacgt agggaagact gcgcgtcacc ataccatgtt
    49441 tgaaatgctg gggaacttct ctatcgggga ttacttccgt gacgaagcta tcacttgggc
    49501 ttatgagctt ttgacaagcc ctgaatggtt tgatttccct gctgaaaaac tttacatgac
    49561 ctactatcca gacgataaag attcttacaa ccgctggatt gaagtgggag tggatccaag
    49621 tcacttgatt ccaattgagg acaacttctg ggaaatcggt gcgggacctt ctggaccaga
    49681 tacagaaatc ttctttgacc gtggggaagc ctttgaccca gaaaatatcg gtcttcgcct
    49741 gcttgcagaa gatattgaaa acgaccgtta tattgaaatc tggaacatcg ttttgtcaca
    49801 atttaacgca gaccctgctg ttcctcgtag cgaatacaag gaattgccac ataagaacat
    49861 tgatacgggc gctggtttgg agcgtttggt ggccgttatc caaggggcta agaccaactt
    49921 tgaaacggac ctcttcatgc cgattatccg tgaagtcgag aaattgtctg gtaaggttta
    49981 tgaccaagat ggcgacaaca tgagcttcaa ggttatcgca gaccacattc gttctctttc
    50041 atttgctatc ggtgatggtg cccttccagg aaatgaaggt cgtggttatg ttcttcgtcg
    50101 tcttctccgt cgtgcttcta tgcatggtca aaaattgggt atcaacgagc ctttccttta
    50161 caaattggtt ccaactgttg gaaaaatcat ggaaagctac tacccagaag tgcttgagaa
    50221 acgtgacttt attgagaaaa tcgttaagag cgaagaagaa tcatttgccc gtacccttca
    50281 ctcaggtcaa cactttgccc aaggcattgt ggcagacttg aaagaaaaag gtcaatctgt
    50341 cattgctggt caagatgtct ttaaactcta tgatacttat gggttcccag ttgaattgac
    50401 tgaagaaatc gctgaagaag ctggtatgac tgtagaccgt gaaggttttg aagcagccat
    50461 gaaagaacag caagaacgcg cgcgtgcgtc agctgtcaag ggtggctcaa tgggtatgca
    50521 aaatgaaact cttcaaaaca tcactgtaga aagtgtcttc aactacaata ctagccaatt
    50581 gtcttctaaa ttggtagcta tcgttgctga caatgcagaa gtaggagctg tttcagaagg
    50641 aactgcctct cttatctttg cggaaacgtc attttatgct gaaatgggtg gacaggtagc
    50701 tgactacgga caaatcttgg atgagtcagg taagattgtg gctactgtga ccaatgttca
    50761 gaaagcccca aatggtcaag cccttcatac agttgaagtc cttgcaccgc ttgccttgaa
    50821 ccaagaatat accttggcaa ttgatagcaa tcgccgtcac cgtgtcatga aaaaccacac
    50881 tgcgactcat ttgcttcacg ctgcccttca caatatcctt ggaaaccacg caacacaggc
    50941 aggatctctt aacgaagttg aattccttcg ctttgacttt acccacttcc aagcagtaac
    51001 tgctgaggaa cttcgtgcga ttgaacagca agttaacgag aaaatttggg aagcacttga
    51061 agtgaagaca gttgaaacgg atattgacac tgctaaagaa atgggagcta tggccctctt
    51121 tggtgagaaa tacggcaagg aagttcgtgt cgtgactatc ggtgactact ctattgaact
    51181 ttgtggtggt actcatgttg acaacacttc tgagattggt ctcttcaaaa ttgtcaaaga
    51241 agaaggaatc ggttcaggaa ctcgccgtat cttggcagtg actggtaagg aagcctttga
    51301 agcctatcgt gaacaagagg atgctcttaa agctatcgca gcaaccttga aagcacctca
    51361 agtcaaggaa gtacctcaca aggtagaagg acttcaagaa caacttcgtc aacttcaaaa
    51421 agaaaatgct gagttgaaag aaaaagccgc agctgcagcc gcaggcgata tcttcaaaga
    51481 tgttaaggaa gtcaacggtc atcgttacat tgctagtcaa gtgtctgtat ccgatgccgg
    51541 tgcccttcgt acttttgcag ataactggaa acaaaaagac tactctgatc ttcttgtcct
    51601 agttgccgct atcggtgaca aagtcaatgt ccttgtagca agcaagacaa aagaccttca
    51661 tgcaggaaac cttgtcaaag aattagcacc aatcatcgat ggacgtggtg gtggtaaacc
    51721 agacatggcc atggcaggag gaagcaacca agctaagatc caagaattgt tggatgcagt
    51781 agcaggtaaa ttgtaatcaa gtaaagatct atccatttgg gtaggtcttt ttgtgaatac
    51841 aaaaaagcca aatccgcttg gacctagctt ggttattatg agctattaga tggtattgac
    51901 tgcccagaca cttacggatc tagctgagac agggaattgt ccataacctt cctcatcaat
    51961 tgtaacttga ccttggtggt taccaagtaa atctacaaag gtttgattag tccattcttg
    52021 accgacaaac attgacttgc tgttttcttg gtcatttgag ataaggactg cgattgggga
    52081 ttgattttca gcacctgaac gtacccaacc gatacagtta gcatggtcaa agtagtcatt
    52141 ttgttctcca taggccaagt cttttcggat ggctaggagg cggtcaagga tttctttgaa
    52201 atcttcttga gcatactggc ctgaaatccc atagtagtct ccgtaaaaga cacatggaag
    52261 gccgtcttgg cgtaacaaaa tgagggcata ggctgctggc ttgaaccatt cttcaacggt
    52321 agactcaagg gcttgtcctc gttgggtatc gtggttgtcg acaaaagtca cagccttgtc
    52381 aggcttgagt tcaaccaggc tatctgtgaa aatgccacga aggtcatagt ttgcgccagc
    52441 ttgactggct tcaaagagat tctggtggag acgaacatcg acaaggtcaa agtgttcttc
    52501 cgttttttcg agatagtcca gattggcttc cttgtctggg ttccaaaatt caccaaaaac
    52561 atagaaatcg tcaccgtatt tttccttcat atcgcggatg aagttgcgca taaagaaaga
    52621 gtcaatatgc ttaacggcat ccaaacggaa accagctaca ccagtcgttt ccatgaacca
    52681 atcagcccag tcatagatgt tttggatgac ttcaggatgt ttaaagtcta ggtcggcata
    52741 catgaggtag tcgtagtttc cgttttcgtt atcgaccaat tccttgttag cccagccctt
    52801 gttgtcccct tggatcagat aaatcccaga tttactgcgt ttggcatcgt agtctgtacc
    52861 ggtgaagtgg taccaatgcc agtggaagcc attataggta tcttggcgac catcgaaggt
    52921 aaaactagtc cagccattga tggtgaaggg ttctccaagt tcaactgtac ggtctacagg
    52981 atcaacttcg ataacctgaa aggcttccct gttatcggca gcagccttgt ggttgagaac
    53041 tacatcggcc ataggttgaa ttccctgttc tttaagggct tgaatggctt gaagatagtc
    53101 ttctttgaaa ccatacttgg tgcggacagt ccctttttgg ttgaactctc ctaagtcaaa
    53161 taagtcatag accccatagc cgacatcttt ttcgttggtt gccttgaagg ctggtggcat
    53221 ccagacgtga ctgatcccca gatgagctag gtgtggagca ttttcagcca gacgcgtcca
    53281 gtgttgaccg tcgtggggca gataccattc aaagtattgc atgagtgttt gattttgcat
    53341 gatgtttcct cttacttgtc aatcttgttc tttattctat cataaagtat ctctcggcgc
    53401 aaacgtttgc gtaagataga aggaaactat tttaactact taaaataaag tattgatttt
    53461 tttgtatcaa agtgctagta tagcgatgta taatacagat aaagatagga gttgtcccat
    53521 gattgaattt caaaatgtta gtaagttgta tggtgataaa gaggccttga gtaatctcaa
    53581 tttgcagatt gaaaatggag agattatggg cttgattggt cataatgggg ctggaaaatc
    53641 gaccaccata aaatccctag tcagtatcat ttcacccagc agtggtcgta ttttggtaga
    53701 cggtcaggag ttatcggaaa atcgcttggc gatcaaacga aagattggct acgtagcaga
    53761 ctcgcctgac ttatttttac gcttaacggc caatgaattt tgggaattga tcgcttcatc
    53821 ctatgatctg actagctctg acttggagac tagtctagct aggctattga acgtttttga
    53881 ttttgctgaa aaccgctatc aggttattga aactctttct cacggaatgc gtcagaaagt
    53941 ctttgtcatt ggggcactct tgtctgctcc tgatatttgg gttttggacg aacccttgac
    54001 tggtttggat ccccaggccg cctttgattt gaagcaaatg atgaaggaac atgcacaaaa
    54061 aggcaagacg gtcttgtttt caactcatgt ccttgaggta gccgagcaag tctgtgatcg
    54121 gattgctatt ttgaaaaagg ggcatttgat ctattgtggt agtgtagaga acttgaggaa
    54181 agaccaccca gaccagtttt tggaaagtat ctaccttagt cttgctggta gaaaagagga
    54241 ggttgcggat gcgtctcaag gtcattaaaa aattagttga tatcaatatc ctctattcat
    54301 ctcaagaagc taatctggct aatctacgaa agaagcaggc taagaatcct gggaaaaaag
    54361 taaatgtttc tgctagagtc ctaagttctt acattttttc cagtctcttg atgctcatct
    54421 gttttagtaa tatagccatt cattttcctt ttgaggaaat gcctatttat tttagctcga
    54481 tggttgctat tttactggtg ctggcctttt caacttcttt cactgccttt tacaatgtct
    54541 tttatgagag taaggacctg gcctcctata ggccctatgc ctttaaagaa tcagagatta
    54601 taatggccaa aggtctgtct gtcctcttgc cagctctaac tggaattgta ccaatcctag
    54661 cttattttct agccctctat attagtctag ctccttctct ttggctgggt ttgcctttga
    54721 tgctactgtc cttgacctta ttatttgtct ctgttacttt agtgacggta gtggcagtac
    54781 atttcttggc tcagactagg gtcttcagaa agtatcagtc tattttttcg aatgtgatga
    54841 ttgggatagg agttctcata cctttaatat ttatcttctt tcttcagtcg acttttggaa
    54901 gtattgttga caaagttaga gacattccat ttctccttta tcctcttcat atcttttaca
    54961 aaatagcagt ggagcctttt tcgacagaag ccttagtggg tctgctcgct tggataggac
    55021 taactctctt cctgctttat ctgaccaaaa agaaggtcct tcctcgtttt tatgacgtga
    55081 tcctgcttaa cagtgaggag aaggtcaaaa aagaacgtcg cagcaaggag aggatttcaa
    55141 ctactaaaaa gggctttttc cgtatggttt tacgctacca cctcaccctc ttgggacagg
    55201 ggactggtgt gattacagtg ctttttacaa gtgctttcct tccttatctc atgatgatca
    55261 gtctgatttc caaaatccga gattctcaga tagttccaga cattcatcct ccatactggt
    55321 tacccttgtt ttttgtagga gtgtttatag cagttgtcaa taacaatatc accagcctgc
    55381 attcaattgc cttgtccttg gagagggaaa atgttgattt tctgaagagt ttaccctttg
    55441 actttgctcg ttatgtgaaa gtgaaatttt ggattatctt tgctgttcag tcctttttac
    55501 cagttctgac tttgctcggt ctttctctat atctaggctt gcccatcctt tcgatgattt
    55561 accttcttgt agtctggatc attgccagtg tcatcctttc ttgccaccat tactttaagg
    55621 acgttaaaaa tctgtcaacc aattggagta gcattacgga cctggtgaat cgttcaaatg
    55681 gcatagtcgc catagtttta ttgtttattt atagtgcaat cctgatggcc cttgtaattg
    55741 ggagcatatt cttggttcag tctctctccc ctatccttgc catcaacttg ggagtaggag
    55801 ctcttatcgt cttgcttgct cttgctattt ttggctatca ttattacctg tcacgcatat
    55861 tggcagaaat agaaaaaaga tgagatagtt ggttgcttgc ttgataaatt caattcgaca
    55921 aacgctttta tagtttgtta gaatgtagtt gtaaatgatt aagattggta atcaaaaata
    55981 tagggaggaa tgttttgaat aagaaatata atatagttct attattgttg tttatagttt
    56041 atttattggg atatttttca atttcaaaaa cgttaattcc tataatgtgt gtgatccaag
    56101 tatttttgat agaacatata tttagagttc gaaatagaat gatgcaaata ggtgaaattt
    56161 taattattgt tgcttctata atattattta ttgatagtat attgagtttg taacaaaagg
    56221 cttttctata aaatcaaatt ttccagatac ctattgaagc agatttattt cttcatcttt
    56281 cttctactac ctttgtcact aaatttgaca gacacatatt gctgattcaa cctctctacc
    56341 tataatctca cagttaacct gaggctagtt tcatagtttg ctatttgatt ttcgttgata
    56401 aaaagaaatg ctcctccaag atggaagagc attttttatt gtgattctta cacatttact
    56461 tcctagtttt gcaggaagtc tagtatacca ttttttaaaa gaagagtaaa aaagcaaggg
    56521 tagtttcttt tttgagaatt gtctaaaagt ttgatataat ggtagttatg aatagaataa
    56581 gagtcagcaa aagggttgaa aagaagcttg ctaaggggct agttttacta gaagccagtg
    56641 atcttgagaa tgtcaatctt aaggatcagg aagtagaggt gcagggtcag gaaggaaact
    56701 ttcttgggac tgcctacctt tctcagcaaa acaagggctt gggctggttt gtcagcaaag
    56761 acaaggtggc cttcaatcaa gctttctttg aaacgttgtt tagaaaagcc aaagaaaaga
    56821 gaaacgccta ctatcaagat gatttgacaa ctgcctttcg tctctttaat caagagggag
    56881 atggctttgg gggtctgaca gtggaccttt atggcgacta cgccgtcttt tcttggtata
    56941 actcttatgt ttatcagatt cgtcagacta tatcagaagc ctttagacag gttttccctg
    57001 aggttttagg agcttatgag aaaatccgct ttaagggttt ggactatgaa tctgcccatg
    57061 tttatggtca agaagcacct gactttttca ctgttttaga aaatggtgtc ctgtatcaag
    57121 tctttatgaa tgatggcttg atgacaggaa ttttcctaga ccagcatgag gttcgcggta
    57181 gtttagttga cggcttggct atgggtaaat ccttactcaa tatgttttcc tacacagcgg
    57241 ctttttcagt agctgcggcc atgggaggag ctagccagac aacttctgtt gatctagcca
    57301 aacgttcacg agaattgtct caagcgcatt ttcaggcaaa tgggctcagc acagacgagc
    57361 atcgttttat agtcatggat gtctttgagt atttcaaata tgccaaacgc aaagacttga
    57421 cctacgatgt gattgtccta gatccgccta gctttgctcg gaataaaaaa caaactttct
    57481 ctgtggccaa ggattatcac aagttgattt cccagagtct tgagatttta aatccgggag
    57541 ggattatcat tgccagtacc aatgctgcca atgtttcccg tcagaaattt acagaacaaa
    57601 ttgataaagg ttttgcagga agaagttacc agattttaaa caaatatggt cttccagcag
    57661 attttgccta taataaaaaa gatgaaagta gtaattacct caaggtgatt agtatgaagg
    57721 ttagtaaatg aaattaatcg tttcagtaat gccaagaagt ttagaggagg ctcaggctct
    57781 ggatgccacg aggtacttgg atgccgacat cattgaatgg cgtgccgact atctgcctaa
    57841 agaagcgatt ttgcaggtag ctccagccat ttttgaaaaa ttcgcaggcc gtgagttggt
    57901 tttcacgcta cgaactcgct ccgaaggtgg agaaatcgac ctttctccag aagagtatat
    57961 ccatctaatc aaggaagttg cgcaactcta tcaaccagac tatattgatt ttgagtacta
    58021 tagctacaag gatgtttttg aggaaatgct ggacttccca aatcttgttt tgagttacca
    58081 taatttccaa gaaacacctg agaacatgat ggaaatcttg tcagagttga cgatcctaaa
    58141 tccaaaactt gttaaggttg cggtgatggc tcacacggag caggatgtct tagacttgat
    58201 gaactataca cgaggcttta aaaccctcaa tcctgaacag gaatatgtga ccatttctat
    58261 gggtaaggtg ggcaaggtct ctcgtatcac tgcggatgtg actggttcga gttggtcttt
    58321 tgccagtctg gatgaggtta gtgcccctgg gcagatttct ctagctagca tgaaaaaaat
    58381 cagggagatt ttggatgaag cttgatggct atacacgttt agctgcagtt gttgccaatc
    58441 ctattaagca ttctatttct cccttcatcc acaatagagc ctttgaggcg acagctacca
    58501 acggtgctta tgtggcttgg gagattgaag cgagtgactt ggcagaaaca gtggccaata
    58561 ttcgtcgcta ccagatgttt ggcatcaatc tgtccatgcc ctataaggag caggtgattc
    58621 cttatttgga tgagctaagc gatgaagcgc gcttgattgg tgcggttaat acggttgtca
    58681 atgagaatgg caatttaatt ggatataata cagatggcaa gggatttttt aagtgcttgc
    58741 cttcttttac aatttcaggt aaaaagatga ccctgctggg tgcaggtggt gcggctaaat
    58801 caatcttggc acaggctatt ttggatggcg tcagtcagat ttcggtcttt gttcgttccg
    58861 tttctatgga aaaaacaaga ccttacctag acaagttaca ggagcagaca ggctttaaag
    58921 tggatttgtg tgctttagaa tatgtttctg aactgcaagc aaggattgcc gagtcggatt
    58981 tgctagttaa tgccaccagt gtgggcatgg atggccaatc ctctcctgtt cctgaaaaca
    59041 tagtcttacc agaaactctt ttagttgcag atatcatata ccaacccttt gaaacaccgt
    59101 ttttgaaatg ggctagaagt cagggcaatc cagcagtcaa tggtctggga atgttgctct
    59161 atcaagctgc agaagctttt caactgtgga caggcaagga aatgccgaca gaagagattt
    59221 ggcagtcttt aacagaaaaa taccaataaa gaaagggaga ctctcctatg aaaatcagaa
    59281 tcgatattcc tcatcatcct tatgatattc agattgaaaa aggttgtatg gcccaggctg
    59341 gtcagtggtt gcgagaactc tggcaaccgc aaaaggtagt cattgtgaca gataaccatg
    59401 tagcctctct ctatgcagag aaggtcaagc tcagcctaga agatgctggt tttcaggtag
    59461 ctgtttttga tttcttagaa ggtgaagaaa gaaagaattt aactactgtt cagaaagtct
    59521 atgaatttct agtcaagcaa ggtctgactc gtagcgatgg aatcgttgct cttggtggtg
    59581 gcgttgttgg ggacctggct ggctttgtag cctctaccta tatgcggggt attcactttg
    59641 ttcagattcc gactagtttg acagctcagg ttgattcttc tatcggtgga aagacaggcg
    59701 ttaacacacc atttgctaaa aatatggtgg ggacctttgc ccaaccagat ggggttctga
    59761 ttgatccact tgttcttgaa accctcggaa aaagagagtt gattgaaggg atgggtgaag
    59821 ttatcaagta tggcttgatt gaggatccag aactgtgggc tctcttgacg ggactgaatg
    59881 gttctgttga gagtattttg gaacatgcag agaccttgat tgaacattct tgtcaggtga
    59941 agcgcaagat ggtggttgaa gatgagttgg acaatggtat tcgtctttac ctcaattttg
    60001 gccacactat tggccatgcc atcgaagcga ctgccggtta tggcaaggtc atgcatggag
    60061 aggctgttgc catgggaatg gtacagattt ccaagattgc tgaggaaaaa ggcctcatgc
    60121 cagctggcat tacccaatct atcacagaga tgtgtcagaa attcggcttg cctgttgact
    60181 atgaaaattg ggaagttgac aagctttatc aggctcttac tcatgacaag aaagcgcgtg
    60241 gcaacacctt gaaattggtc ttggtgccag agcttggttc agcgatcatt cacccagttt
    60301 ctctggaaga gatgaaagac tacttggtaa aataaggaga gtgtatgaga tatttaactg
    60361 caggagaatc acacggcccc cgtctaacag ctattattga tggaattcca gctggacttc
    60421 cattgacagc tgaggatatc aatgaggacc ttagacgccg tcagggtggc tacggtcgtg
    60481 gtggtcgtat gaagattgag aatgaccagg ttgtctttac ttcgggcgtt cgccacggga
    60541 agacgacagg ggcgcctatt actatggatg tcatcaataa ggaccaccag aaatggctgg
    60601 acatcatgtc tgcggaggac attgaagacc gtcttaaaag caagcggaaa attactcatc
    60661 ctcgcccagg tcatgccgat ttggttgggg ggattaagta ccgttttgat gatttgcgaa
    60721 attctttgga gcgttcatca gctcgtgaaa ccaccatgcg ggtggcagtt ggtgcagtag
    60781 ccaaacgcct cttggctgag ttggatatgg agattgccaa ccatgtcgtg gtctttggtg
    60841 gcaaggaaat cgatgttcct gaaaatctga cagtcgctga aattaagcaa agagctgccc
    60901 agtctgaagt ttctattgtc aaccaagaac gagaacagga aatcaaggac tatattgacc
    60961 aaatcaaacg tgatggtgat accatcggtg gggttgtgga gacagtcgtc ggaggcgttc
    61021 cagttggtct tggttcctat gtccaatggg atagaaaatt ggatgcaaga ttggctcaag
    61081 ctgttgtctc tatcaatgcc tttaaagggg tggaatttgg tcttggcttt gaggctggtt
    61141 atcgtaaagg cagccaagtt atggatgaaa ttctctggtc taaagaagac ggttatactc
    61201 gccgtaccaa taatctaggt ggttttgaag gtggtatgac taatgggcaa cccatcgttg
    61261 ttcgtggggt catgaaaccc attcctactc tttataaacc tcttatgagt gtggatatcg
    61321 aaacccacga accttacaag gcaaccgtgg agagaagtga tccgactgct cttccagctg
    61381 caggaatggt catggaagca gttgtagcaa cggttctggc gcaagaaatc ctcgaaaaat
    61441 tctcatcaga taatcttgag gaactaaaag aagcggtagc caaacaccga gactatacaa
    61501 agaactatta aggagttcct atggcaaaaa caatctatat cgcaggtctt gggttgattg
    61561 gagcctctat ggcacttggt atcaaacgcg atcatccaga ttatgaaatt ttaggttata
    61621 atcgtagtca agcttcgaga gatatcgcct tgaaagaagg catgattgac cgtgcaacgg
    61681 atgattttgc tagttttgct cctttggcag atgtcattat cctcagcttg ccaatcaaac
    61741 aaactattgc tttcattaag gagttggcca atttggattt gcgagaaggc gttattattt
    61801 cagatgctgg ttcgaccaag tcaaccattg tggatgcggc ggagcagtat ttggctggca
    61861 agtctgttcg ctttgtcggg gcccatccca tggctggtag tcacaagaca ggggctgctt
    61921 cggcagatgt caatcttttt gaaaatgcct attatatctt tacaccttca agcctgacaa
    61981 gtcaggacac gcttaaggaa atgaaggatc tgctttcagg tcttcatgct cgttttatcg
    62041 agattgatgc caaggagcat gatcgtgtca cttctcagat tagccatttt cctcatattt
    62101 tggcttctag tctcatggag cagactgcgg tctatgctca agagcatgag atggcaaggc
    62161 gctttgcggc aggtggtttt cgagatatga cccgaattgc ggaaagcgag ccaggaatgt
    62221 ggacctccat tctcttgtcc aatagcgaga tcattctgga tagaattgag gatttcaagg
    62281 aacgtttgga agcgattggt caggccatta gtaagggaga tgaagagcaa atttggaact
    62341 tttttaacca agcgcgtgaa caacgccaga ccatggaaat ccataagcgt ggtggtgtgg
    62401 atagctctta cgacctctat gttgacgttc ctgatgaaga agatgtcatc ctgcggattt
    62461 tggaactgct acgtggaact tccttggtta atatccacat caacgaggaa aatcgtgagg
    62521 atattcacgg aatcctacaa atttcattta aaaatgctca agacttggaa agagctgagc
    62581 atctcataac agaaaatact gactatacag tcgtcatcaa ataaggagaa gaacatgtca
    62641 aatatttacg atagtgcaaa cgaactcagt cgcggtctac gcggattacc agaatacaag
    62701 gctgttaaag cagctaaaga tgcgattgca gcagatgctg aggcaagcaa aatctttaca
    62761 gattatcttg cctttcaaga ggaaattcaa aaactagcac agacaggtca aatgccagat
    62821 gcgtccttcc aagctaagat ggaaggcttt ggtaaacaga ttcaaggaaa tagcctcttg
    62881 tcagaattct ttaccaagca acaacaattg gccatttacc tttctgacat tgaaaaaatt
    62941 gtttttgaac cagtttcaga attgctgaaa taagaaaaga actatcctaa agtcaggaat
    63001 ttttaaggaa tttctggctt tttatgataa aataggtaaa agtattgcaa gtatgaggtc
    63061 cagtatgaaa ctaaaaacaa acattcgcca tttacatggt agtatccgcg tcccaggtga
    63121 caagtctatc agccaccgtt ccattatctt tggaagtttg gctgagggtg agaccaaggt
    63181 ttatgatatt ctgcgaggcg aagacgttct ttcgaccatg caggtttttc gtgaccttgg
    63241 tgttgaaatt gaggataaag atggggttat taccattcaa ggtgtaggca tggctggctt
    63301 aaaagcgccg caaaatgccc ttaatatggg aaattctggc acctcgattc gcctgatttc
    63361 aggtgtcctt gctggtgcag atttcgaagt agagatgttt ggagatgata gtctttccaa
    63421 acgtcctatg gaccgtgtga cccttccact gaaaaaaatg ggcgtcagca tttcagggca
    63481 aactgaacga gacttgcctc cccttcgctt aaaagggacg aaaaacctaa gccctattca
    63541 ttatgagttg ccaattgcct ctgcccaagt caagtcagcc ttgatgtttg cagccttaca
    63601 agctaagggg gagtcagtta ttatcgaaaa agaatacacc cgtaatcata ctgaagatat
    63661 gttgcaacaa tttggtggtc atttaagtgt ggatggtaag aaaatcacag tccaagggcc
    63721 acaaaaattg acaggacaga aggtggtcgt accaggagat atttccagtg cagccttttg
    63781 gttagtcgca ggtttgattg ctccaaattc tcgtctagtg ctgcagaatg tggggatcaa
    63841 cgaaactcgc accggtatta ttgatgtcat tcgtgccatg ggtggaaaat tggaaataac
    63901 tgaaatcgat ccagtcgcta aatctgcaac cttgattgtt gagtcttctg acttgaaagg
    63961 aacagagatt tgtggcgctt tgattccacg tttgattgat gaattgccta ttattgccct
    64021 acttgcgacc caagcccaag gtgtaacagt tattaaagat gctgaggagc tcaaggtcaa
    64081 ggaaacagac cgtattcagg ttgtggcaga cgccttaaat agtatgggag cagatattac
    64141 tcctacggca gatgggatga ttatcaaagg aaaatcagct cttcacggtg ctagagtcaa
    64201 tacgtttggt gaccaccgta tcggcatgat gacagctatc gcagccctat tggttgcaga
    64261 tggagaggtg gagcttgacc gtgcagaagc catcaatacc agctatccta gtttctttga
    64321 tgatttggag agcttgattc atggctaagg tgttattagg gtttatgggg gctggaaaat
    64381 caactattgc aagaggcttg gaccctaatt accttgatat ggatgctctg attgagaagc
    64441 gcctaggtat gtccattgcg aattttttcg ctgaaaaggg agaatcagcc tttcgtcagg
    64501 tagaatcaga agtcctagct gatttactac aaacagacca agtcgtgtca actggaggag
    64561 gagtggttat ttctcagaga aatcgtgact tactcaagac taatacagat aacatctacc
    64621 tgaaagcaga ttttgaaacc ctctacctac gtatcgtagc tgataaggac aatcagcgac
    64681 cgctttttct aaataatagc aaggaagaac tagtagctat ttttcaagaa agacaggctt
    64741 ggtatgagga agtggctagt cgggttttgg atgtgaccaa gctaagccca gaggaaatta
    64801 tagaggaact aagatgaaaa ttgcttatct aggtcccaaa ggatcatttt cacaccacgt
    64861 tgtgcagaca gcttttcctc atgaggaatt gcaggctttt gccaacatta cagatgttat
    64921 caaggcttat gagcaaggat tagtggacta ttctgtggtg ccagttgaaa attctattga
    64981 gggtagtgtt catgaaacct tggactatct ttttcatcag gctcacatcc aagcagtagc
    65041 agaaatcgtt cagcctattc atcagcagtt gatggtggtt ccaggccata ctaagattga
    65101 aaagattttt tcacatccac aggccttggc tcaaggaaag aaattcatcg atgaacaata
    65161 tccagaggct caaatcgagg taacagctag tacagcttat gcggcccgtt ttatttccga
    65221 acatccagac cagccctttg cagcagttgc acctagaagt tctgctgaag aatatggatt
    65281 ggaactgatt gccgaggata ttcaggaaat ggaagccaat ttcacacgtt tctgggttct
    65341 aggagctgaa aagcctagta ttcccttgca agcacaaact gaaaagatga gtttggcctt
    65401 gacattacct gacaaccttc caggtgcact ttataaggcc ctgtcgacct ttgcttggcg
    65461 aggaattgac ttgacaaaaa ttgaaagtcg tccactcaag acagcactgg gtgaatactt
    65521 tttcattatc gatgtggatt ataccgataa ggacttggtc cactttgccc aaaaagaatt
    65581 agaagcgatt ggaatccagt ataaaattct gggtgcctat cctatttatc caatatcaga
    65641 ccatggaaag gagagaagat gagtaaagaa aatcccttaa gtcatcatga gcagttgcgt
    65701 tatgattatt tgctaaaaaa tattcactac ctcaatgaga gagaaaaaaa tgagtttgcc
    65761 tatttgcaag aaaagctaac tcttgctagg agaaatagta gctctagctt ggaacaagaa
    65821 agagaagagc aggttgactt accaagttat gcgaaccgga gtcgctcaca atccaaatca
    65881 caagcactct cttcccctcc aaaaaagaaa agacggaagc tccgtcttaa acgaattttt
    65941 atggtgattt tttcactttt ggtctgtgtg gctttggcca tggtattcat gtttttgcgt
    66001 ggttaccaag atgctagcgc aaagaaaact gctgatgccc gggcagctca agtagaagtc
    66061 tttaatggtc aggacactag agatggagtt aatattttaa tcatgggtac tgatggtcga
    66121 atcggccaga acagtgttga gacacgaact gactctatta tggtattaaa tgtcgggggc
    66181 tcagataaga aaatgaagct agtcagtttc atgcgtgata atttggtcta tatagatggt
    66241 tatagtcaag tgattaacgg tagaaaacag acagataaca agttaaacgt agcctacgag
    66301 ttaggagaac aagaggggca aaaaggggca gaaatggttc gccaagtctt gaaagataat
    66361 tttgacttgg acattaagta ctacgccttg gttgatttcc aggcctttgc cacagcgatt
    66421 gacacacttt tccctgatgg ggtgacgatt gatgctcaat tttcaacatt gaatgggcgt
    66481 cccctaacag aagctacagt cggagatgat ttatacgcta ccgagactga gtctccaacc
    66541 caaaccatta aagtcggaaa acagcagatg aatggctcga ccctgctcaa ttatgctcgt
    66601 ttccgtgatg atgatgaggc ggattacggc cgtacaaaaa gacagcaaca agttttaaca
    66661 gcaattttag agcaaattaa agatcccact aaacttttca ctggttctga agctcttgga
    66721 aaggtttttg ctatgacctc aaccaacgta ccctatactt tcctcctaac aaacggttta
    66781 tctgttttgg atggagcaaa aaatggtatt gaaaaattga cgattccaga actgggtgac
    66841 tgggtagatg cctatgatgt ttatggaggc ttgggcttgc tggttgatca aaacaaatat
    66901 caaaccaagc tcgctcaaat gggcttgaga taagataata ctcaatgaaa atcaaagtgc
    66961 aaactaggaa gctagccgca ggctgctaaa aacacagttt tgaggttata gataagactg
    67021 acgaagtcag ttacctatac ctacggcaag gtgaagctga cgtgctttga agagattttc
    67081 gaagagtata agacagaaaa atcaaagttt gatagctatt tggatagcag tcaggctttg
    67141 attttttaca gtctgcaata gattttcacc ccttgtttgt ggtataatga aacgatacga
    67201 tagaaagaat aatgaacaat atgactgatt taaaagcaat tcaggctcgt agtctggaga
    67261 tggctgaata ttttgtggcc ttttgtaaag aacatgattt gctctgttat ctctgtggcg
    67321 gaggcgctat tggtaccctt cgaaacaagg gatttattcc ttgggacgac gacctagact
    67381 tttttatgcc tcgtaaagat tatgagaaat tagcagaatt atggcctcgt tatgcagatg
    67441 aacgttattt cttgtcaaag agttacaagg attttgttga tcgtaatctt tttattacca
    67501 ttcgtgacaa ggaaaccacc tgtatcaagc cttatcagca ggatttggat ttgccacatg
    67561 gtctggcctt ggatgttttg cctttggatt attatccgaa agatccagct gagcggaaaa
    67621 aacaggttcg ttgggccttg atttattcac tcttttgtgc gcaaactatt ccagaaaagc
    67681 atggtgctct catgaaatgg ggaagtcgca ttttactggg tttgactcca aaatctctcc
    67741 gttatcgcat ctggaaaaaa gctgagaaag aaatgactaa gtatgatttg gctgattgtg
    67801 atggcattac agaattatgc tcaggtcctg gctacatgag aaacaagtac ccaatcacat
    67861 cttttgaaga caatcttttc ttgccatttg agggaacaga gatgcctatt ccaatcggct
    67921 atgatgtcta tctcagaact gcttttgggg attatatgac gcctccacca gcagacaagc
    67981 aggtaccgca tcatgatgct gtcatcgctg atatggataa gtcttataca gaatacaagg
    68041 gagaatatgg tggctaagaa aaaaatctta ttttttatgt ggtctttttc tcttggaggt
    68101 ggtgcagaga agattctatc aaccattgtt tcaaatctgg atccagaaaa gtatgatatt
    68161 gatattcttg aaatggagca ctttgacaag ggatatgaat ctgttccaaa gcatgtacgc
    68221 attttaaaat cccttcaaga ttatcgccaa accagatggt tacgagcttt tttgtggaga
    68281 atgagaattt attttccaag actggctcgt cgtttgcttg taaaagatga ttatgatgtt
    68341 gaagtttctt ttaccattat gaatccacca ctgttgttct ctaaaagaag agaagtcaag
    68401 aagatatctt ggattcatgg aagtattgaa gaacttctta aggatagctc taaaagagaa
    68461 tcacatagaa gccagttgga tgctgcgaat acaattgtag ggatttcaaa aaagaccagc
    68521 aattctatca aggaagttta tccagattat gcttctaaat tacagacaat ctacaatgga
    68581 tatgattttc agactattct agaaaaatct caagagaaga tcgatatcga gattgctcct
    68641 caaagtatct gtactatcgg acggattgag gaaaataagg gttctgaccg tgtagtggaa
    68701 gtgatacgat tattacacca agagggaaaa aactatcatc tctattttat cggggctggt
    68761 gatatggaag aggaactgaa aaaacgagtc aaagagtatg ggattgagga ctatgtacat
    68821 ttccttggtt atcaaaaaaa tccttatcag tatttatctc agacgaaagt tctcttgtct
    68881 atgtctaaac aagaaggttt tcctggagtg tatgtggagg ccttgagtct gggactccct
    68941 tttatctcta cggacgttgg aggggctgag gaattatccc aagaaggacg atttggacaa
    69001 atcattgaga gcaatcaaga ggcagctcag gcgattacta attacatgac ttctgcctca
    69061 aactttgatg tcgatgaggc tagccaattc attcaacaat ttacaattac aaaacaaatc
    69121 gaacaagtag aaaaactatt agaggagtag catggaaact gcattaatta gtgtgattgt
    69181 gccagtctat aatgtggcgc agtacctaga aaaatcgata gcttccattc agaagcagat
    69241 ctatcaaaat ctggaaatta ttcttgttga tgatggtgca acagatgaaa gtggtcgctt
    69301 gtgtgactca atcgctgaac aagatgacag ggtgtcagtg cttcataaaa agaacgaagg
    69361 attgtcgcaa gcacgaaatg atgggatgaa gcaggctcac ggggattatc tgatttttat
    69421 tgactcagat gattatatcc atccagaaat gattcagagc ttatatgagc aattagttca
    69481 agaagatgcg gatgtttcaa gctgtggtgt catgaatgtc tatgctaatg atgaaagccc
    69541 acagtcagcc aatcaggatg actattttgt ctgtgattct caaacatttc taaaggaata
    69601 cctcataggt gaaaaaatac ctgggacgat ttgcaataag ctaatcaaga gacagattgc
    69661 aactgcccta tcctttccta aggggttgat ttacgaagat gcctattacc attttgattt
    69721 aatcaagttg gccaagaagt atgtggttaa tactaaaccc tattattact atttccatag
    69781 aggggatagt attacgacca aaccctatgc agagaaggat ttagcctata ttgatatcta
    69841 ccaaaagttt tataatgaag ttgtgaaaaa ctatcctgac ttgaaagagg tcgctttttt
    69901 cagattggcc tatgcccact tctttattct ggataagatg ttgctagatg atcagtataa
    69961 acagtttgaa gcctattctc agattcatcg ttttttaaaa ggccatgcct ttgctatttc
    70021 taggaatcca attttccgta aggggagaag aattagtgct ttggccctat tcataaatat
    70081 ttccttatat cgattcttat tactgaaaaa tattgaaaaa tctaaaaaat tacattagaa
    70141 cgggggtgac caagtgattg atgggaaacg attattattt agtttgacca tagtcagtta
    70201 tgccttgacg ctagtaagtg gaattgtgta tctgtttaat aataataatg ttagcttact
    70261 ttctacttta ttgttcttgt tggttagtag cttaattgct tgttggaatg atatcaagta
    70321 ttacttaatc cattttattt tctatttaac catttttgta tttctggtat caagaccgac
    70381 cattgattat tttagggatg gtgctttgga tacctatcat ccaatagcct atcgttttgc
    70441 ctttatagtt gtcatggttt cgattctggg cttgaccaca ggaggcattc tggctcgtta
    70501 cttcatagct aggaagaaaa taaaagtagc aaatatagga aattctctaa aagaggttta
    70561 tatcaagcgg ttacgctttg tatcactagg agtttttctt ctaacctatc ctttctattt
    70621 cattcggtta tttgaacggc tcttgtatcg tttgcagact tcctactatg cctactatgc
    70681 aaattttgaa agtaaactgc cttattttac ctacattttg tctaccttta cggtctatgc
    70741 aatgtgtatg tatctggcaa ccaagccaaa gaaattgcag gccacagcag tgcttgtctc
    70801 ctttattgca gctaatacta ttcatttggc aattgggaca cgaaatccct ttattttaag
    70861 tattttattt gcttttgttt attactttat gcgggagcaa actgaaaaag gaaaatggat
    70921 tgggtttaaa gaaaagttag cgatttttgt aggttctcct attctcatgt tagcgatggg
    70981 agtactcaat tatgtacggg ataatgtcca agtttcccat acaggtttct gggatatctt
    71041 acttgacttt atctataaac aagggactag ttttggtgtt ctggctcgag gttttctatt
    71101 taacagtagc ctcccttacc gagatttccg taattttact tttggtcctg ttcttgatta
    71161 ttttgcaagg gggagtttgg gagccatttt cggaggaaaa gcctttgaac atacaaccaa
    71221 tagtgtggaa ctagctattg atagtaatag ttatgcccac aatctatcct atcttgtctt
    71281 gaacaaggaa tacctgaaag ggcatggtat cggaagtagt tatatcatgg agttgtatac
    71341 cgactatggt atgattggag tctttctgct tagtttctta ctcggcgtat tatttatagc
    71401 catgctgcaa gtagcctatc gctcaaggac aatcctattt gctttatccc tactcatctt
    71461 gaataatcta ttctttatgc caagaagcag cttttcagaa agtttcttca atttatttac
    71521 aatgcaattc tggggaattg ttcttgtgat tatatttata gcaaaaatgc ttacaaagga
    71581 aaactagtat ctactaaaca aaggagaaaa aaatcatgtt tgaacattat tcagtagctg
    71641 atttgtttgc aaatctttat aaaaagcgaa aagcaaatat tttagctctc atcgctttat
    71701 ttgctctcat tgctgtacca tttacaatta aagcagttag gaataaaaac actgtcaaag
    71761 atacaacaag ttattcaact tatcttatct ataaaatcac tcctccaaaa gagtcggcca
    71821 aaacgatttt gaatcatcaa attggtggtt atagtgattt ttatgggaaa ttgattgatg
    71881 gtaatttgaa tggagcttat cttttcaatg atgtagaacc cagtgagttg aaaaaaattg
    71941 ccagtgaatt agacacgaca gaaacaacct tgaaaaattc aacgaatgac tattggtgga
    72001 aaaaattgac cgtctactat atgattgacg atgcaggggt tggtgtgaaa attttgacat
    72061 caagtaaaga tgccaatgac ttgttagaga aaaaaattga tgggttgatt gagaaattta
    72121 aacatgccta tgcaaatgtg aaaattgaaa aactggaaac catcaactct aaagaattga
    72181 acgcaaatgg tgaaacagcg cttggcttaa atgtgaaaaa tctgattctt cgtttagttg
    72241 ttattggagt ggtttgtgtg attttggttg tgatgggaaa tgtgttagtt tatctcttta
    72301 atccaacaat caatagagta ggtgattttt ctcagtatca aattgatttt gtaacagaga
    72361 ttacaacaat tgctaaccta gcagatgttt tgtcatacaa aaatactgga caggaattga
    72421 ccatcgttag ctcaaataaa gctatcctag ataaattgaa acagagtcaa gaagctttaa
    72481 aaggaatgca ttttgtagat ttacaggatg tatcatctct tttggaaaga gatacagtcc
    72541 ttcttgttga agagtacgga gtgactcgtt ataagaaatt tgagcaaagt cttcaaattc
    72601 tcagaaactt aaatcgttct atcctcggtg tagcaacctt taaattataa gtattctgat
    72661 gtataaggtc ttcaaagtcg gctaagagcc gattttgaag gctttttcta tctgtctgca
    72721 gaaattttct tttgataaaa tcgtaaaaat ctagtataat agatagaact gaaagtatga
    72781 ggttactagc aatgaaaatg aaacaaatta gtgatacaac tttaaaaatc acgatatctt
    72841 tagaggattt gatggatcgt ggaatggaga ttgctgactt tctcgttcct caagaaaaaa
    72901 cagaagagtt cttttatgct atcttggatg agctagagat gcctgatagc tttctggata
    72961 caggcatgtt gagcttccgt gtgactccaa aacctgataa ggtagatgtc tttgtgacca
    73021 agtcaaagat tgaccaaaat ctagattttg aagacttatc ggatttgcca gatatggaag
    73081 aattggctca aatgtctcca gatgaattta tcaaaaccct ggaaaaaagc atcgcagaca
    73141 aaaccaagga tgatatcgaa gccattcaat ctcttgagca agttgaagcc aaggaagaag
    73201 aacaagagca ggctgaacaa gaagctgaga gtaagaaaga accttacatc tactacatcc
    73261 tttcttttgc taagttggct gacttggtag cttttgccaa gacagtgact tttgaaatgg
    73321 aaacttctga actctacaaa atgaacgagc gctattattt gaccatttta gtggatattg
    73381 aaaatcatcc aagcccatat ccagcttggc tgttggcccg tatgcgcgag tttgcagagg
    73441 atagtgatat cagtcgctca gtcttacaag agtatggtca agttttgatg agtcacgatg
    73501 cagtgctcaa tctgcaaaaa atcggctaat cttttctgga aagctatttt cagattttaa
    73561 gaagagcgaa tcgtctgatt cgttttttct ttttatactg aaatagtgat ttactataat
    73621 aggaattttc acaaaattct gttataatgg ctatattaga aaatttcgag gagataaaga
    73681 tgacagttaa aattgcttta ctaggatttg gtaccgttgc aagtggtgtg cctttcctcc
    73741 taaaggaaaa tggaggaaaa atcaatcaat cagcacattc agatatcaaa gttgctaagg
    73801 tattggtcaa ggatgaagat gaaaaaaatc gcttgcttgc agcagggaat gactttaact
    73861 ttgtaaccaa tgtggatgat attttatcag accaggatat tactatcgta gtggaattga
    73921 tggggcgtat tgagcctgct aaaaccttta tcactcgtgc cttggaagct ggaaaacacg
    73981 ttgttactgc taacaaggac cttttagctg tccatggcgc agaattgcta gaaatcgctc
    74041 aagctaacaa ggtagcactt tactacgaag cagcagttgc tggtgggatt ccaattcttc
    74101 gtactttagc aaattccttg gcttctgata aaattacgcg cgtgcttgga gtagtcaacg
    74161 gaacttccaa cttcatggtg accaagatgg tggaagaagg ctggtcttac gatgatgctc
    74221 ttgcggaagc acaacgtcta ggatttgcag aaagcgatcc gacgaatgac gtagatggga
    74281 ttgatgcagc ctacaagatg gttattttga gccaatttgc ctttggcatg aagattgcct
    74341 ttgatgatgt agtccacaag ggaatccgca atatcacacc agaagacgta gctgtagctc
    74401 aagagcttgg ttacgtagtg aaattggttg gttctattga ggaaacttct tcaggtattg
    74461 ctgcagaagt gactccaacc ttcctaccta aagcgcaccc acttgctagt gtgaatggcg
    74521 taatgaacgc tgtctttgta gaatctatcg gtattggtga gtctatgtac tacggaccag
    74581 gtgcgggtca aaaaccaact gcaacaagtg ttgtagctga tattgtccgt atcgttcgtc
    74641 gtttgaatga tggtactatt ggcaaagact tcaacgaata tagccgtgac ttggtcttgg
    74701 caaatcctga agatgtcaaa gcaaactact atttctcaat cttggctcca gactcaaaag
    74761 gtcaggtctt gaagttggct gaaatcttca atgctcaaga tatttccttt aagcaaatcc
    74821 ttcaagatgg caaagagggt gacaaggcgc gtgtcgttat catcacacac aagattaata
    74881 aagcccagct tgaaaatgtc tcagctgaat tgaagaaggt ttcagaattc gacctcttga
    74941 ataccttcaa ggtgctagga gaataagatg aagattattg tacctgcaac cagtgccaat
    75001 atcgggccag gttttgactc ggtcggtgta gctgtaacca agtatcttca aattgaggtc
    75061 tgcgaagaac gagatgagtg gctgattgaa caccagattg gcaaatggat tccacatgat
    75121 gagcgtaatc tcttgctcaa aatcgcttta caaattgtac cagacttgca accaagacgc
    75181 ttgaaaatga ccagtgatgt ccctttggcg cgcggtttgg gttcttccag ctcggttatc
    75241 gttgctggga ttgaactagc caaccaactg ggtcaactca acttatcaga ccatgaaaaa
    75301 ttgcagttag cgaccaagat tgaagggcat cctgacaatg tggctccagc catttatggt
    75361 aatctcgtta ttgcaagttc tgttgaaggg caagtctctg ctatcgtagc agactttcca
    75421 gagtgtgatt ttctagctta cattccaaac tatgaattac gtactcgcga cagccgtagt
    75481 gtcttgccta aaaaattgtc ttataaggaa gctgttgctg caagttctat cgccaatgta
    75541 gcggttgctg ccttgttggc aggagacatg gtgaccgctg ggcaagcaat cgagggagac
    75601 ctcttccatg agcgctatcg tcaggacttg gtaagagaat ttgcgatgat taagcaagtg
    75661 accaaagaaa atggggccta tgcaacctac ctttctggtg ctgggccgac agttatggtt
    75721 ctggcttctc atgacaagat gccaacaatt aaggcagaat tggaaaagca acctttcaaa
    75781 ggaaaactgc atgacttgag agttgatacc caaggtgtcc gtgtagaagc aaaataaaga
    75841 atagaagata ggatggggaa actcttgacc agagggtttc atatcctttt tgtgaaaaga
    75901 agtttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa
    75961 cagtgttttg aggttgcaga tagaactgac gaagtcagta acatatatac ggtaaggtga
    76021 cgctgacgtg gtttgaagag attttcgaag agtattagtt aaaaacgtga taaaggagaa
    76081 ataaagatgg cagaaattta tctagcaggt ggttgttttt ggggcctaga ggaatatttt
    76141 tcacgcattt ctggagtgct agaaaccagt gttggctacg ctaatggtca agtcgaaacg
    76201 accaattacc agttgatcaa ggaaacagac catgcagaaa cggtccaagt gatttacgat
    76261 gagaaggaag tgtcactcag agagatttta ctttattatt tccgagttat cgatcctcta
    76321 tctatcaatc aacaagggaa tgaccgtggt cgccaatatc gaactgggat ttattatcag
    76381 gatgaagcag atttgccagc tatctacaca gtggtacagg agcaggaacg catgctgggt
    76441 cgaaagattg cagtagaagt ggagcaatta cgccactaca ttctggctga agactaccac
    76501 caagattatc tcaggaagaa tccttcaggt tactgtcata tcgatgtgac cgatgctgat
    76561 aagccattga ttgatgcagc aaactatgaa aagcctagtc aagaggtgtt gaaggccagt
    76621 ctatctgaag agtcttatcg tgtcacacaa gaagctgcta cagaggctcc atttaccaat
    76681 gcctatgacc aaacctttga agaggggatt tatgtagata ttacgacagg tgagccactc
    76741 ttttttgcca aggataagtt tgcttcaggt tgtggttggc caagttttag ccgtccgatt
    76801 tccaaagagt tgattcatta ttacaaggat ctgagccatg gaatggagcg aattgaagtt
    76861 cgttctcgtt caggcagtgc tcacttgggt catgttttca cagatggacc gcgggagtta
    76921 ggcggcctcc gttactgtat caattctgct tctttacgct ttgtggccaa ggatgagatg
    76981 gaaaaagcag gatatggcta tctattgcct tacttaaaca aataaaacag agagtggggc
    77041 ttcccacttt cttcatttct agaatatgaa tagaagggat ttatgaaaca cctattatct
    77101 tacttcaaac cctacatcaa ggaatcaatt ttagccccct tgttcaagct gttagaagct
    77161 gtttttgagc tcttggttcc catggtgatt gctgggattg ttgaccaatc tttacctcag
    77221 ggagatcaag gtcatctctg gatgcagatt ggcctgctcc ttatctttgc agtaattggc
    77281 gttttagtgg ccttgatagc tcaattttac tcagcaaagg cagcagtagg ttttgctaag
    77341 gaattgacaa acgatcttta tcgtcatatt ctttccttgc ccaaggacag cagagaccgt
    77401 ctgacaacat ctagtttggt cactcgcttg acttcggata cctaccagat tcagactggt
    77461 atcaatcaat tcctgcgtct ctttttgcga gcgcccatta tcgtttttgg tgccattttt
    77521 atggcttatc gaatctcaac tgagttgact ttctggttct tagtcatggt tgccattttg
    77581 accattgtca ttgtagggtt atctcgattg gtcaatcctc tctacagtag tctcagaaag
    77641 aaaacggacc aactggttca ggaaacgcgc cagcaattgc aagggatgcg ggttattcgt
    77701 gcttttggtc aagaaaaacg agagttacag atttttcaaa cccttaacca agtttatgct
    77761 agattacaag aaaagacagg tttctggtct agtttattaa cacctctgac ctatctgatt
    77821 gtcaatggaa ctcttctcgt tattatctgg caaggctata tttcaattca aggaggagtg
    77881 ctcagtcaag gtgctctcat tgctcttatc aattacctct tacagatttt ggtggaattg
    77941 gtcaagctag ccatgttgat caattccctc aaccagtcct atatctcagt caagcgaatc
    78001 gaggaagtct ttgttgaggc tccagaggat atccattcag agttagaaca aaagcaagct
    78061 accagagata aggttttaca agtccaagaa ttgactttta cctatcctga tgcggcccag
    78121 ccttctctga gatacatttc ctttgatatg actcaaggac aaattctagg tatcatcggg
    78181 ggaactggtt ctggtaaatc aagcttggtg caactcttac ttggacttta tccagtagac
    78241 aaggggaaca ttgaccttta tcaaaatgga cgtagtcctc ttaatttgga gcagtggcgg
    78301 tcttggattg cctatgtacc tcaaaaggtc gaactcttta aaggaaccat tcgttccaac
    78361 ttgactctag gtttcaatca agaagtatct gaccaggaac tctggcaggc cttggagatt
    78421 gcgcaagcta aggattttgt cagtgaaaag gaaggactct tggatgctct agttgaggca
    78481 ggggggcgaa atttctcagg tggacaaaaa caaagattgt ctatcgcccg agcagtcttg
    78541 cgccaagctc cgtttctcat cctagatgat gcaacctcgg cactggatac cattacagag
    78601 tccaagctct tgaaagctat tagagaaaat tttccaaaca cgagcttaat tttgatctct
    78661 caacgaacct caactttaca gatggcggac cagattctcc tcttggaaaa aggtgagttg
    78721 ctagctgttg gcaagcacga tgacttgatg aaatccagcc aagtctattg tgaaatcaat
    78781 gcatcccaac atggaaagga ggactagaat gaaacgacaa actgtaaacc agacgctcaa
    78841 acgtttagcc gtagatttag caagccatcc tttcctcctt ttcctagcct ttctaggaac
    78901 tattgctcaa gttggcttat caatttacct acctattctg attgggcagg tcattgacca
    78961 agtcctagtg gctggttcat caccagtttt ttggcagatt tttctccaga tgctcttggt
    79021 ggtaatagga aatactctgg tacaatgggc caatcctctc ctctataatc gtctaatctt
    79081 ctcttatacc agagatttac gggagcgaat catccataag ctccatcgtt taccgattgc
    79141 ctttgtagat aggcaaggta gtggagagat ggttagtcgt gtaaccacgg acatcgaaca
    79201 gttggcagct ggcttgacca tgatttttaa ccaatttttc attggtgttt tgatgatttt
    79261 ggtcagtatt ctagccatgc tccaaattca tctcctcatg actctcttag tcttgctgtt
    79321 gacgccactg tccatggtga tttcacgctt tattgccaag aaatcctatc atctcttcca
    79381 gaagcaaaca gagacgaggg gaattcagac tcagttgatt gaagaatcgc ttagtcagca
    79441 gactataatc cagtccttca atgctcaaac agaatttatc caaagattgc gtgaggctca
    79501 tgacaactac tcaggctatt ctcagtcagc catcttttat tcttcaacgg tcaatccttc
    79561 gactcgcttt gtaaatgcac tcatttatgc ccttttagct ggagtaggag cttatcgtat
    79621 catgatgggt tcagccttga ccgtcggtcg tttagtgact tttttgaact atgttcagca
    79681 atacaccaag ccctttaacg atatttcttc agtgctagct gagttgcaaa gtgctctggc
    79741 ttgcgtagag cgtatctatg gagtcttaga tagccctgaa gtggctgaaa caggtaagga
    79801 agtcttgacg accagtgacc aagttaaggg agctatttcc tttaaacatg tctcttttgg
    79861 ctaccatcct gaaaaaattt tgattaagga cttgtctatc gatattccag ctggtagtaa
    79921 ggtagccatc gttggtccga caggtgctgg aaaatcaact cttatcaatc tccttatgcg
    79981 tttttatccc attagctcgg gagatatctt gctggatggg caatccattt atgattatac
    80041 acgagtatca ttgagacagc agtttggtat ggtgcttcaa gaaacctggc tcacacaagg
    80101 gaccattcat gataatattg cctttggcaa tcctgaagcc agtcgagagc aagtaattgc
    80161 tgctgccaaa gcagctaatg cagacttttt catccaacag ttgccacagg gatacgatac
    80221 caagttggaa aatgctggag aatctctctc tgtcggccaa gctcagctct tgaccatagc
    80281 ccgagtcttt ctggctattc caaagattct tatcttagac gaggcaactt cttccattga
    80341 tacacggaca gaagtgctgg tacaggatgc ctttgcaaaa ctcatgaagg gccgcacaag
    80401 tttcatcatt gctcaccgtt tgtcaaccat tcaggatgcg gatttaattc ttgtcttagt
    80461 agatggtgat attgttgaat atggtaacca tcaagaactc atggatagaa agggtaagta
    80521 ttaccaaatg caaaaagctg cggcttttag ttctgaataa gccattctct tttgaaagtt
    80581 tatggacgaa aaaagttgcc ttcgagtgac ttttttgtta caatagctag aaaaattgtt
    80641 cactgtaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgta ggttgctcaa
    80701 agcacagctt tgaggttgta gataagactg acgaagtcag ttcaaaacac tgttttgagg
    80761 ttgcagatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg
    80821 acgaagtcag taaccacacc tacggcaaag tgaatctgaa gtggtttgaa gagagtacaa
    80881 cttgtctttt agaaaaggag cctataatga aagtctttca gcatgtaaat atcgtgactt
    80941 gtgatcaaga tttccatgtt tatcttgatg gaatcttagc agtcaaggat tctcaaatcg
    81001 tctatgtcgg tcaagataag ccagcgtttt tagagcaagc tgagcagatt atagactatc
    81061 agggagcttg gattatgcct ggtttggtca attgtcacac ccattctgca atgacaggtc
    81121 tgagagggat ccgagatgac agcaatctcc atgaatggct caatgactat atttggccag
    81181 cagaatctga gtttactccc gacatgacta ccaatgcggt caaagaagcc ctgacagaga
    81241 tgctccagtc aggaacaaca acctttaacg atatgtataa tcccaatggt gtggatatcc
    81301 agcaaattta tcaggtggtg aaaacttcca agatgcgttg ttatttttct ccgactctct
    81361 tttcttcaga gacagaaaca actgctgaga ctataagtag aactcgatcc atcatagacg
    81421 aaatcttaaa atataaaaat ccaaatttca aggttatggt agcacctcat tctccgtata
    81481 gctgcagtag agacttgctg gaagcgagtt tggaaatggc aaaagagcta aatattccgc
    81541 tccatgtcca tgtggcggag accaaggagg agtcaggaat tatcctcaaa cgatacggca
    81601 aacgccccct tgcttttctt gaagaactgg gttatttaga tcatccgtcc gtatttgctc
    81661 acggggtcga attaaacgag agagaaattg aacgcttggc atcttctcaa gtggctatcg
    81721 cccacaatcc tatcagtaac ctcaaactgg catcaggaat tgctccaatt atccagctcc
    81781 aaaaagcggg agtagcagtc ggaattgcga ctgactcggt tgcttccaat aacaatctag
    81841 atatgtttga ggaaggaagg actgcagctc ttcttcagaa gatgaaaagt ggggatgcca
    81901 gccagtttcc aatcgaaaca gctctcaagg tactgacaat cgaaggggct aaggtccttg
    81961 gaatggaaaa tcagatagga agtctggaag tcggcaagca agcagatttt ctggtcattc
    82021 aaccacaagg gaaaattcat ctccaacctc aggaaaatat gctgtctcac ctggtttatg
    82081 cagttaaatc tagtgatgta gatgatgttt atatcgccgg agaacaggtt gttaagcaag
    82141 gtcaagtcct gacagtagaa ctttaaaaga aaaattacga aaaattttaa aaaaagtttg
    82201 caaaaatctt gcattctttt tttgactatg ctatacttat atacggttta aaaaaactgc
    82261 ctaagacagt aggggagctc gactcataaa tatcctaccg aggacaaaac gtatcatgta
    82321 aaaagaagcg tattgtactt tcgtgtctag gtttgggcgc gtttttcttt ttgaaaaatt
    82381 ccccaagcaa aataattacg gaggtgaaca cactaatgag tgaagcaatt attgctaaaa
    82441 aagcggaact agttgacgta gtagctgaaa aaatgaaagc tgctgcatct atcgtcgttg
    82501 tagacgctcg tggtttgaca gttgagcaag atacagttct tcgtcgtgag cttcgtggaa
    82561 gcgaagttga gtataaagtt attaaaaact caatcttgcg tcgtgcagct gaaaaagctg
    82621 gtcttgaaga tcttgcatct gtatttgttg gaccatctgc agtagcattt tctaatgaag
    82681 atgttatcgc accagcgaaa atcttgaacg acttttctaa aaacgctgaa gcacttgaaa
    82741 ttaaaggtgg tgcaatcgaa ggcgctgtcg catctaaaga agagattctt gcacttgcaa
    82801 ctcttccaaa ccgcgaagga cttctttcta tgctcctttc tgtacttcaa gcgccagtgc
    82861 gcaacgttgc tcttgcagtc aaagcggttg cagaaagcaa agaagacgcg gcttaatctt
    82921 aagctacaca gcgtagctta gctacgaaaa aaactattat aaaatttaaa acttatttgg
    82981 aggaaataac aatggcattg aacattgaaa acattattgc tgaaattaaa gaagcttcaa
    83041 tccttgaatt gaacgacctt gtaaaagcta tcgaagaaga atttggtgta actgcagctg
    83101 ctcctgtagc tgttgctgca gctgatgcag ctgatgctgg tgctgctaaa gattcattcg
    83161 acgttgaatt gacatctgca ggcgacaaaa aagttggcgt tatcaaagtt gtacgtgaaa
    83221 tcactggtct tggtcttaaa gaagctaaag aacttgttga cggtgcacca gcacttgtta
    83281 aagaaggcgt tgcaactgca gaagctgaag aaatcaaagc taaattggaa gaagctggag
    83341 cttcagttac tcttaaataa tagagtatcg caatttgatt gcggaatccc tatttaccag
    83401 tctttgagag cgataagcga ttgatagaaa ctgataaatt gatttggttt cctgccaaaa
    83461 attctttggc aggatttttg ttttaataaa ctttcggggg tagacactag attgtctacc
    83521 cctttttttg tgtttcggag gtaattatgc aaaaggaagg acagtcatca cgtcaattcg
    83581 tgaagagtca tctcatgact atcatgggag ttgatattgt aaaagcaact cagttagttg
    83641 atgaaatgga acaagtaggt ttaatccgat ttgatgaatt tggaaatgtt ggaattttag
    83701 tcttggaggg acaataatga agcgtattac cgctaatcaa tatcagacat cagagcgtta
    83761 ttataagctc cccaaacttt tatttgagag tgaacggtat aagaatatga aactggaggt
    83821 taaggtggtt tactcagttt taaaagatcg gttggagttg tctttgagca aaggttggat
    83881 tgatgaggat ggggctattt atttgattta ttccaattca aatttgatgg cacttttagg
    83941 ctgttcaaag tcaaaattac tctccatgtg agtttgaagt gatattttta gatgattacc
    84001 ataaaaaaca taactaccca ctattttacg aatcctatct tcaaaacgtt atggaattcc
    84061 ttgaaagtca agacataaag aatggggttg atgcctttgt agatgatcat caaaatctcg
    84121 tttttgtttt atatggacaa ggctatcgag ccgagggaaa agagggaata cttacaaccc
    84181 aagtaactgt aaaagcttat gatgaagaca agaaaccgat taacttcgca aatttattag
    84241 attccttaat ttattagatt ccttaatcgt gtcagaatat caaatggaac cgaatctttg
    84301 ggaggtctcc catgattgat ctctatctaa gtaaaaatag acaaagaaat caacttcttt
    84361 tagatttctt ccaaaactat ggcatagagg tatcttgtca ttcagtttct gaaatgacaa
    84421 aggacaaatt aattgagatg atgagctatt cttcagattg ttttgagttt ttatctccca
    84481 atttattacg atttaagaac cgtgacaatc taagattaac ggatttcgtt gagataattt
    84541 taaaaaatcc tgaactaacc atcagacttc ctcttgcggt ttcaaataag cgagtttatc
    84601 caagtctgaa tttggaagag gctagagctc tattgccaag agatacgaaa caattgattt
    84661 acatggcgca aacacattat ttatctaact aaaggagaag caatatggct gaacgatttt
    84721 gggagaactt gtccattatt ttggctgaaa gaaatatcag ctggattgag ttaaccagaa
    84781 aaatgtttgc gggagagttt cactatccaa gtgaattgaa tcgtttgtat caaaagattc
    84841 gccactagaa gatggaacaa tgaatgcctc aaagtccatg ggtagaaagg attgtgcagg
    84901 tattagattt agattatgaa gatttatttc ggaggtaact atgaaaagaa taattccagt
    84961 ttatatattc caacaagtaa atgtcctatt ggtatctcta tacttattga aatttctttg
    85021 tatcggtgag ttaactatac tacagattct ctatggttcg tcactcattt cttttttatg
    85081 gatgtatggc caacgcaaac aagcgcataa ggtcaatatg aaatctagga tgaaatggct
    85141 tggtgttgaa tttgttagcc tactgattat aagtctatgt tttagtctga ttcatgctca
    85201 aggaagcacg aatcaagcaa acttaattgg ccttcaacat caaattcctt ggttttcatt
    85261 tttattgttc ttaatcaatg cgagtatggt tgaagaattt ctgtatcgag aaattttatg
    85321 gaatttggtc agaaaattag atatcagagt tgctttgaca agtgttttat ttgccttagc
    85381 acatcatcca ggaaccatta tagcttggtg tttgtatgta tcgctgggga tgtttttagg
    85441 gcttgtacgc tacaaattgg acttatgggg cagtatgggg ctacatttgg tgtggagcct
    85501 actagtttat agtttgctgc ttttttaaaa taggtaacct gatttttagg taacttctaa
    85561 aactaacttc cagttttggg agagagatgg aagttacttt gaaaagttac ggaaacatta
    85621 ttttctacgt gacaacattg tatcattgct tgcattttac tgctggagag agtataatga
    85681 aggtggataa agcacttaat cccaaaaatt taaataggag gagttagcta tggcagaaga
    85741 agtattaaat cttcaattag tatctgttca agttgacgaa acagatgaag ttgatggaat
    85801 gcgatttagt acattcagta caaaccgttg cggtaactgg agtgctttta gttgggaaaa
    85861 ttgttaattc atttaaattg taaactttag ggattctctg gagttatgga tctcgttcca
    85921 atatgtgcac gttggaatgt cagtgcttat atggggggaa tccaaaggat tctccctttt
    85981 tattttaata agtctgtcta gctatagata tattaagttt gatagaattt cttggagatt
    86041 ttgttatgga ttataatttc aatttggagc atcctttctt tttcactaat aatgattata
    86101 gtacagatac tagcataaag tactaagtaa gtctgccttt taattggcac gaagtaatga
    86161 ataatgatga gtgggtttat caatacccta ttggaaaatt tgttgaaaga caagggtgga
    86221 aaatacacat tagttcagag tataatagtt cacacgaatt gttacaagat gtagcaaaaa
    86281 tttgccatga aatgcgaatt ccatttaaac atcttagtac agaagacaaa tttatcatgc
    86341 gaaacgggaa attggttagt cgaggatttt ctggtaaatt tattacatgt tatccaaatc
    86401 aaaatgaatt agagtcggtt ttgcaaaggt tagaaagtgc cttaaagcaa tataatgggc
    86461 catatatttt aagcgataaa cgttgggatg aagcaccaat atatctgagg tatggtgtgt
    86521 ttaggccgtc aagggatgat gaaaagaagg ttgttattga tgaattaatt gttggcgatg
    86581 aagttgttaa agatgaacgt ttaccagtat ttaaaattcc aaaaggtata gtgccccctg
    86641 actttttgaa taaatggctt gacaagaaag ataaaaaaca gggagacttt ccctttatta
    86701 tagataatgc aattagattt tcaaacagtg gtgggatata taatgctaga ctaaaagaag
    86761 atgggaaaaa aataatttta aaagaggcta gaccgtatac aggtctagga tttgatggta
    86821 cttattcttc agagagatta gcttcggagt gcaaagcact aaaaattcta aatgaatgga
    86881 gtgagatgcc taaaatatac tggtacggta agatctggga gcacaccttc ttaggaattg
    86941 aacatatgaa gggcgttcca ctaaatagat gggttaccaa taattttcct ttatatgaag
    87001 ttgttgataa gaccaaagat tatctattga gagtttcaaa gatagtagaa aaactcatcg
    87061 atttaacgaa taagtttcat tctgaaaatg tatatcatca agatttacat ttaggaaata
    87121 tcttggttaa ggatgaagat gagattagta taatagactg ggaacaggct gtcttttcga
    87181 atgatgaaaa agttgtacat aaagttgcag cccctggttt tagagcatgg cgagaaacac
    87241 ttcccagtga gatagattgg tatggtatta gacaaatagc tcattattta tacatgccac
    87301 tagtaactac atcggatttg acatacaact atgtaagtca aaccaggata gaaggaaaaa
    87361 aactatttga gtctttgggt tatacaagag aacatataga ttatgtagaa agtttattgt
    87421 catatctaga ttctaaatgt ccacagattg agaatatttc caggaaaaaa gttttaaaac
    87481 ccatgcatga gattagaact atcgagagtg agcaagatat acaagatttt attataaaag
    87541 cttttctttt agtgaactga taggtatttt cttagcaaac gataaagttt tagggccgat
    87601 acaatcaatt gcctattcat taaataagat aaatacaacc aaagatttaa ggaaaccgtt
    87661 tttaaaatac ttaagtggag agaagaattt tatagacgct gaacatgata ataacggact
    87721 gtatacttca tcaatagatg tgatacacat gaaagatgtt gtatattcta ttacaccaga
    87781 aaataaatta agtattgact tctcatttaa gtcaccattt agggtattat taacaggaac
    87841 ttctggtagt gggaaaacaa cgattttaaa tttaattaat ggttctttaa agccacaaaa
    87901 aggttatgta aatttgttat cacatgggaa aaagagttca gattcaatac caacagttga
    87961 tcagacacca tatatttttg acactactat tcgtgagaac gtaactttat ttcaaaatga
    88021 atatttttca gatgatcaga taattgaggt gttaaaaaag gtaaatctat atgaagaatt
    88081 agaaaagata gatatactaa attatcaatg tggtgaaaat ggtagtaatt tgtctggagg
    88141 tcaaaaacaa aaaatagctt tagctagagc tctgattaga aataataaag tgtacttatt
    88201 tgacgaaata tcagctaatt tagataatga taattcaaat tccatacatg atattctgtt
    88261 caatttaggt atttcattta ttgaagtttc acatcattat gacttaaatg acaagagata
    88321 cactgatata taaattggaa aatggaacac ttttcaaaat taagtgattg gaggcaagaa
    88381 tatggataaa gattatatat taaaagtgaa agggctgtat catcaatttt tactgggaaa
    88441 caataaaacg ttgcaagtgc tgaaaaatgt ttctctttct gcttcgagag gagaatttat
    88501 aagtattcta ggaattagtg gttctggaaa gtcaacttta ttaaaatgta tttctagttt
    88561 gcttgaacca acaagtgggg aagtaatttt aaatggaatc aacccctata aaatcagaaa
    88621 tgcaaaattg tcaagtataa gacgtaacga agtatctttt atatttcaag catacaattt
    88681 aataccttcc ctgccggtaa tagaaaatat agcacttcct ttgcgattat cacaaaaaaa
    88741 attaactatt aaaaatgtag aaaacttact caaaagaatg aagtttaatg ctggcttaaa
    88801 cgattttgtt ggaactctgt ctggtggaga acaacagaag gttgctatag ctagagcggt
    88861 tattgctgat agtgatataa tatttgctga tgagccaact ggggctttag acagcgtttc
    88921 tcgtgaagta atttttgaat tattgagaga gttagtaggg gcgggtaagt gtgtaattat
    88981 ggtaacgcac gatatagaat tggcctcgaa aactgatcgt gcattaatat tgaaagatgg
    89041 aaaaattttc aaagaacttc atagacctag cggggaagag ttgtataaaa tcttagaggt
    89101 acaatcaact acggaggaat agagatgctc agattagttt actatcaatt tttacataat
    89161 aagaaacaat ggttaggcgt ttcaccagta atttttgttt cgagtttagt tatgggattg
    89221 gctgttaatg gggtaattaa tgttgagaat aattcgcaag tatttgtcgg acttccagat
    89281 cctaaaccaa tttttatgtt tccgatagta ttcggaggag taacattatt ctttgtgctc
    89341 tctaacataa taaatatgtt ggttgaaatt tttagagatg attacgaact tctggaggtg
    89401 ttgggagcaa gtctccttca actatcattt cttgtggggg gacagatttt tatcatttcc
    89461 tcgattatta gttttattgc atatctatgc tctatatttg ttacgtcaaa ttattattat
    89521 tttttacaat actttttcgg ggaaaatata ttacctgata tccaatttca aacgagtgct
    89581 gttggatgta tcattacagt agtgttgatt tcatttttag cctttctaag tggttgcttt
    89641 tatacgttca agaagattag aaataggaag agttctaaaa taaggcatgt tctttcaata
    89701 gtaaaaagaa tactgctatt ggctggtttt agtgttatct ggttgctttc tttgcaacaa
    89761 attttccaag atagcacaat tttagcgaag gcccagataa tattcaatat tgtaatctta
    89821 gatattgtga ttatttatca attatctcct tttatacagt catgttttat caaactactt
    89881 tctataatta tatttagaaa taattttatg ttcattgttt cgaagtggaa tttactatat
    89941 cgtaagcctt atataaaatc tatcagtgct gcaattacag gagctatatt actaatttct
    90001 agttttcaaa tgatttctca gaatatacta tctcaatttc aagatgacag tgatttagag
    90061 ctaaaagtgg catttattgt ctatgtagga gcaccaattt tgatagtact tgcaaatatt
    90121 atttcaattg catttttgtc atcgcatcaa gaaaggattg agattcagca atttgaaatt
    90181 ttaggaactt ctaattacca gatggttaag attaaagttg gtgaggctat atttttgaca
    90241 tttgttactt cattaattgc atttttactt aacattaaaa ttatggcttt aatatactac
    90301 tctttagggg atattttaat agatgatatg aatcttttgg ggttaatact tccaaatttt
    90361 atagtgtcta ttattttatt tattttaata tttattacta aaagttccta ttttatcttt
    90421 aagaatgcaa aaattatttc ttaaaaattt gtaagttttc gctatataaa atagttaaat
    90481 ctattttgta tcattgcttg cattttactg gtggagagaa tataatgagg gtggataaag
    90541 tacttaatcc caaaaattta aataggagga gctagctatg gcagaagaag tattaaatct
    90601 tcaattagta tctgttcaag ttgacgaaac agatgaagtt gatggaatgc gatttagtac
    90661 attcagtaca aaccgttgcg gtaactggag tgcttttagt tgggaaaatt gttaattcat
    90721 ttaaattgta aactttaggg attctctgaa gttatggatg tcgttccaat atgtgcacgt
    90781 tggaatgtta gtgcttatat ggggggaaca gaatcctctc ttgattgaag acaagttagc
    90841 ca
//
LOCUS       DBERAE010000003        80431 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.03, whole genome shotgun sequence.
ACCESSION   DBERAE010000003 DBERAE010000000
VERSION     DBERAE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.03"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..607
                     /locus_tag="ACL70N_000266"
                     /pseudo
     CDS             1..607
                     /locus_tag="ACL70N_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(724..1071)
                     /locus_tag="ACL70N_000267"
     CDS             complement(724..1071)
                     /locus_tag="ACL70N_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0589154.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1182..2957)
                     /gene="spxB"
                     /locus_tag="ACL70N_000268"
     CDS             complement(1182..2957)
                     /gene="spxB"
                     /locus_tag="ACL70N_000268"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGS0589155.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3164..5407)
                     /locus_tag="ACL70N_000269"
     CDS             complement(3164..5407)
                     /locus_tag="ACL70N_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS0589156.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPTHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWIISIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5417..5788)
                     /locus_tag="ACL70N_000270"
     CDS             complement(5417..5788)
                     /locus_tag="ACL70N_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGS0589157.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5799..6194)
                     /locus_tag="ACL70N_000271"
     CDS             complement(5799..6194)
                     /locus_tag="ACL70N_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGS0589158.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6378..6476
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6560..7351
                     /gene="thiD"
                     /locus_tag="ACL70N_000272"
     CDS             6560..7351
                     /gene="thiD"
                     /locus_tag="ACL70N_000272"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS0589159.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7561..8193)
                     /gene="thiE"
                     /locus_tag="ACL70N_000273"
     CDS             complement(7561..8193)
                     /gene="thiE"
                     /locus_tag="ACL70N_000273"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS0589160.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITVAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLIGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8186..8989)
                     /locus_tag="ACL70N_000274"
     CDS             complement(8186..8989)
                     /locus_tag="ACL70N_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS0589161.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYVAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8989..9513)
                     /gene="thiW"
                     /locus_tag="ACL70N_000275"
     CDS             complement(8989..9513)
                     /gene="thiW"
                     /locus_tag="ACL70N_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGS0589162.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAIIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9518..10210)
                     /gene="tenA"
                     /locus_tag="ACL70N_000276"
     CDS             complement(9518..10210)
                     /gene="tenA"
                     /locus_tag="ACL70N_000276"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGS0589163.1"
                     /translation="MEFTDIAMELSKKAWQVSFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10221..10871)
                     /locus_tag="ACL70N_000277"
     CDS             complement(10221..10871)
                     /locus_tag="ACL70N_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGS0589164.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCVLFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10873..12258)
                     /locus_tag="ACL70N_000278"
     CDS             complement(10873..12258)
                     /locus_tag="ACL70N_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589165.1"
                     /translation="MGLELRAIQSPIFPEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSPPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTEVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTF
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRDFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12259..12819)
                     /locus_tag="ACL70N_000279"
     CDS             complement(12259..12819)
                     /locus_tag="ACL70N_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0589166.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13081..13169)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13378..14007)
                     /gene="thiE"
                     /locus_tag="ACL70N_000280"
     CDS             complement(13378..14007)
                     /gene="thiE"
                     /locus_tag="ACL70N_000280"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS0589167.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14009..14791)
                     /gene="thiM"
                     /locus_tag="ACL70N_000281"
     CDS             complement(14009..14791)
                     /gene="thiM"
                     /locus_tag="ACL70N_000281"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS0589168.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            14887..15018
                     /locus_tag="ACL70N_000282"
     CDS             14887..15018
                     /locus_tag="ACL70N_000282"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589169.1"
                     /translation="MKIKEQTRRLTAGCSKHCFEPVDKTDEVSSKHCFEVVDRTDVV"
     gene            complement(15073..15741)
                     /locus_tag="ACL70N_000283"
     CDS             complement(15073..15741)
                     /locus_tag="ACL70N_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGS0589170.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15956..16044)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16296..17432)
                     /gene="lctO"
                     /locus_tag="ACL70N_000284"
     CDS             complement(16296..17432)
                     /gene="lctO"
                     /locus_tag="ACL70N_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGS0589171.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18057..19547)
                     /gene="lysS"
                     /locus_tag="ACL70N_000285"
     CDS             complement(18057..19547)
                     /gene="lysS"
                     /locus_tag="ACL70N_000285"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGS0589172.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19687..19821)
                     /locus_tag="ACL70N_000286"
                     /pseudo
     CDS             complement(19687..19821)
                     /locus_tag="ACL70N_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            19854..20192
                     /locus_tag="ACL70N_000287"
                     /pseudo
     CDS             19854..20192
                     /locus_tag="ACL70N_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc.;
                     incomplete; partial in the middle of a contig; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
     gene            20169..20771
                     /locus_tag="ACL70N_000288"
     CDS             20169..20771
                     /locus_tag="ACL70N_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001197618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0589173.1"
                     /translation="MGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLDFTRIMP
                     QLVLLFIVYFGLARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQ
                     ALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDS
                     NRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20772..21530
                     /locus_tag="ACL70N_000289"
     CDS             20772..21530
                     /locus_tag="ACL70N_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0589174.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMHPE
                     IILFDEVTASLDSEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAHAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            21542..22407
                     /locus_tag="ACL70N_000290"
                     /pseudo
     CDS             21542..22407
                     /locus_tag="ACL70N_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22494..23141)
                     /locus_tag="ACL70N_000291"
     CDS             complement(22494..23141)
                     /locus_tag="ACL70N_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589175.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23138..23836)
                     /locus_tag="ACL70N_000292"
     CDS             complement(23138..23836)
                     /locus_tag="ACL70N_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589176.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(23846..24598)
                     /locus_tag="ACL70N_000293"
     CDS             complement(23846..24598)
                     /locus_tag="ACL70N_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589177.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24598..25362)
                     /locus_tag="ACL70N_000294"
     CDS             complement(24598..25362)
                     /locus_tag="ACL70N_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589178.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMVVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25458..25580)
                     /locus_tag="ACL70N_000295"
     CDS             complement(25458..25580)
                     /locus_tag="ACL70N_000295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589179.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            complement(26041..26673)
                     /gene="pyrE"
                     /locus_tag="ACL70N_000296"
     CDS             complement(26041..26673)
                     /gene="pyrE"
                     /locus_tag="ACL70N_000296"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGS0589180.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26707..27408)
                     /gene="pyrF"
                     /locus_tag="ACL70N_000297"
     CDS             complement(26707..27408)
                     /gene="pyrF"
                     /locus_tag="ACL70N_000297"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGS0589181.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            27729..27941
                     /locus_tag="ACL70N_000298"
                     /pseudo
     CDS             27729..27941
                     /locus_tag="ACL70N_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269888.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28143..28856)
                     /locus_tag="ACL70N_000299"
     CDS             complement(28143..28856)
                     /locus_tag="ACL70N_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589182.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFCKYLMETQG
                     KVNDQQELVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28849..29688)
                     /locus_tag="ACL70N_000300"
     CDS             complement(28849..29688)
                     /locus_tag="ACL70N_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589183.1"
                     /translation="MSMIEVSHLSKSFGDKIALNNISFTVKEGQIFGFLGPSGSGKTT
                     TINILTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSK
                     FYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSG
                     LDPTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELI
                     QRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGK
                     LNA"
     gene            complement(30164..31132)
                     /locus_tag="ACL70N_000301"
     CDS             complement(30164..31132)
                     /locus_tag="ACL70N_000301"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HGS0589184.1"
                     /translation="MKELLEIEEVLGSKLTFELLNEQILISDEIDIDSRYSRTKGYYS
                     LFYNEEYNKIQNKTVLVLGAGALGCYISLSLSMYGVRKLIVADYDIIEPSNLNRQILY
                     TESDVGKEKINVLSEKIHKYNSDVQVVPISIKVSSLEELEKIVAEYGSIDFIVKAIDT
                     PIDIIKIVNQFAVSHKISYISGGFNGCYLIIDNIYIPTIGSCFGCRNINKDINKYTLS
                     DKTKWPTTPEMPAILGGIMTNLIIKIFLGCYNETLIDNAYVYNMRNHALSQEKYVLEN
                     GECPICKKNNKVKDNNIRAKTFIRSVCFCLLSGGVAFYLLLGSSLL"
     gene            complement(31234..32031)
                     /locus_tag="ACL70N_000302"
     CDS             complement(31234..32031)
                     /locus_tag="ACL70N_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HGS0589185.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMIGRTKYVLRK"
     gene            complement(32423..32545)
                     /locus_tag="ACL70N_000303"
     CDS             complement(32423..32545)
                     /locus_tag="ACL70N_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589186.1"
                     /translation="MQDNFLFEEIEEISVPVSDFSAGLATGIGFGLAILALAGC"
     gene            complement(32566..32691)
                     /locus_tag="ACL70N_000304"
     CDS             complement(32566..32691)
                     /locus_tag="ACL70N_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589187.1"
                     /translation="MSDEVFLFEEIEEIVAPTDGEFLGEVLLGTGVVLLIGVACC"
     gene            complement(32822..34021)
                     /gene="divIB"
                     /locus_tag="ACL70N_000305"
     CDS             complement(32822..34021)
                     /gene="divIB"
                     /locus_tag="ACL70N_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGS0589188.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            complement(34031..35089)
                     /locus_tag="ACL70N_000306"
     CDS             complement(34031..35089)
                     /locus_tag="ACL70N_000306"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGS0589189.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35093..36445)
                     /gene="murD"
                     /locus_tag="ACL70N_000307"
     CDS             complement(35093..36445)
                     /gene="murD"
                     /locus_tag="ACL70N_000307"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGS0589190.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36549..37190)
                     /locus_tag="ACL70N_000308"
     CDS             complement(36549..37190)
                     /locus_tag="ACL70N_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589191.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37192..39213)
                     /locus_tag="ACL70N_000309"
     CDS             complement(37192..39213)
                     /locus_tag="ACL70N_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS0589192.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39284..39583)
                     /locus_tag="ACL70N_000310"
                     /pseudo
     CDS             complement(39284..39583)
                     /locus_tag="ACL70N_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(39947..40201)
                     /locus_tag="ACL70N_000311"
     CDS             complement(39947..40201)
                     /locus_tag="ACL70N_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGS0589193.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40221..42062)
                     /gene="typA"
                     /locus_tag="ACL70N_000312"
     CDS             complement(40221..42062)
                     /gene="typA"
                     /locus_tag="ACL70N_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGS0589194.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42224..42949
                     /locus_tag="ACL70N_000313"
     CDS             42224..42949
                     /locus_tag="ACL70N_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGS0589195.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42989..43216)
                     /locus_tag="ACL70N_000314"
     CDS             complement(42989..43216)
                     /locus_tag="ACL70N_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589196.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLEYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43305..43685)
                     /locus_tag="ACL70N_000315"
     CDS             complement(43305..43685)
                     /locus_tag="ACL70N_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS0589197.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43685..43954)
                     /locus_tag="ACL70N_000316"
     CDS             complement(43685..43954)
                     /locus_tag="ACL70N_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGS0589198.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            44018..44926
                     /locus_tag="ACL70N_000317"
     CDS             44018..44926
                     /locus_tag="ACL70N_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS0589199.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44980..45735)
                     /locus_tag="ACL70N_000318"
     CDS             complement(44980..45735)
                     /locus_tag="ACL70N_000318"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0589200.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45756..46685)
                     /gene="rnz"
                     /locus_tag="ACL70N_000319"
     CDS             complement(45756..46685)
                     /gene="rnz"
                     /locus_tag="ACL70N_000319"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGS0589201.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46700..47323)
                     /locus_tag="ACL70N_000320"
     CDS             complement(46700..47323)
                     /locus_tag="ACL70N_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGS0589202.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLVQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47316..48554)
                     /gene="hflX"
                     /locus_tag="ACL70N_000321"
     CDS             complement(47316..48554)
                     /gene="hflX"
                     /locus_tag="ACL70N_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGS0589203.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48547..49431)
                     /gene="miaA"
                     /locus_tag="ACL70N_000322"
     CDS             complement(48547..49431)
                     /gene="miaA"
                     /locus_tag="ACL70N_000322"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGS0589204.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHFVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49552..49722
                     /locus_tag="ACL70N_000323"
     CDS             49552..49722
                     /locus_tag="ACL70N_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGS0589205.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49770..50609)
                     /locus_tag="ACL70N_000324"
     CDS             complement(49770..50609)
                     /locus_tag="ACL70N_000324"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGS0589206.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50706..51665)
                     /locus_tag="ACL70N_000325"
     CDS             complement(50706..51665)
                     /locus_tag="ACL70N_000325"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGS0589207.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTVGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51792..52790)
                     /locus_tag="ACL70N_000326"
     CDS             complement(51792..52790)
                     /locus_tag="ACL70N_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGS0589208.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(52840..53457)
                     /locus_tag="ACL70N_000327"
     CDS             complement(52840..53457)
                     /locus_tag="ACL70N_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0589209.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53458..55179)
                     /gene="pabB"
                     /locus_tag="ACL70N_000328"
     CDS             complement(53458..55179)
                     /gene="pabB"
                     /locus_tag="ACL70N_000328"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGS0589210.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55240..60960)
                     /locus_tag="ACL70N_000329"
     CDS             complement(55240..60960)
                     /locus_tag="ACL70N_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0589211.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNYVNK
                     EIISQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYK
                     RKKIASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTL
                     GLDTVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPK
                     EEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPA
                     EESKVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEP
                     KEETVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPE
                     VPEEEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPV
                     LETAKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRS
                     WQNLQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKIL
                     EREAVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYK
                     EYTLSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLIT
                     TIPDDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTHVYKVTAIADNLVSRTADNKFE
                     EEYVHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKE
                     FTGKLLSSEGKQFAITELEHPLFDKIKAGTVKNINFENIDINVSNQDNIATIANEING
                     TTRIENIKATGTITARNNVAGFVNNIKENAALENVAFIGNINSVGNNSTVGGIAGSNY
                     MGFVNKAYVDANITAANASASMLVPLVTYMLNSYQYGTKSKVTNSVAKGTLDVKNTRF
                     VGGVVAKTWPWGVIKDIVTYAKVIKGEEVYGSNEINDGDARQFLSDIYRVNGASSGAN
                     NFTNLQKIKQLTKEQADAKVATFNITADKLESELSPLAKLNEEKAYSSIQDYNAEYNQ
                     AYKNLEKLIPFYNKDYIVYQGNKLNKEHPLNTKEVLSVTAMNNNEFITNLDEANKIIV
                     HYADGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILEPVD
                     LQSQTMYQHLNRLGDYRVNAIKDLYLEESFTAVKKNLTNLITKLVQNEEHQLNDSPAA
                     RQMLRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIE
                     IGSKENNIKGSRTFDAFGEVLAKYTKSGNLDVFLNYNRQLFTNIDNMNDWFIDATKDH
                     VYIAERASEVEEIKNAKYRAYANLNVAQHRKMILPLLNITKSHMFIASNYNAIAIGSA
                     EKLGKKSLEDIKASVDYAADGYRNYYDFWYRLVPDNVKQYLLRDTVIPIWEGYNAPGG
                     WVEKYGRYNTDNVYTPLREFFGPIEKYYGYNGTGAYAALYDNPMDPRSDVSYVALNMI
                     GDYGISVYTHETTHINDRKIYLGGFGRREGTDAEAFAQGMLQLPVPGSGFNEYGSLGL
                     NTVFKKPNDGNQWYDTDPKSLTTRDDIDKYMRGYNDALMLVDHLEADAVINQNNKELN
                     GAWFKKIDKKFRDASQLNQWDEIRNLTTEEKDNLNITSIDSLIDQQLMTNRQIGNRVY
                     KPEVVSQYDQSPYVGVEMTAGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYLNGFLGYT
                     SNKYKQQSTKDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVN
                     GSSVSSYDDLLTLFKEAVKKDAETLKQEANGHKTVSMTNTVKLKEAVYKKLLQQTDSF
                     KTSIFR"
     gene            complement(60982..61545)
                     /locus_tag="ACL70N_000330"
     CDS             complement(60982..61545)
                     /locus_tag="ACL70N_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGS0589212.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(61661..63352)
                     /locus_tag="ACL70N_000331"
     CDS             complement(61661..63352)
                     /locus_tag="ACL70N_000331"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0589213.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63349..64086)
                     /locus_tag="ACL70N_000332"
     CDS             complement(63349..64086)
                     /locus_tag="ACL70N_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0589214.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(64354..65466)
                     /gene="msrB"
                     /locus_tag="ACL70N_000333"
     CDS             complement(64354..65466)
                     /gene="msrB"
                     /locus_tag="ACL70N_000333"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS0589215.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(65477..66043)
                     /locus_tag="ACL70N_000334"
     CDS             complement(65477..66043)
                     /locus_tag="ACL70N_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGS0589216.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(66063..66773)
                     /gene="ccdA2"
                     /locus_tag="ACL70N_000335"
     CDS             complement(66063..66773)
                     /gene="ccdA2"
                     /locus_tag="ACL70N_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS0589217.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            complement(66984..67844)
                     /locus_tag="ACL70N_000336"
     CDS             complement(66984..67844)
                     /locus_tag="ACL70N_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGS0589218.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDQVFKKD"
     gene            complement(68023..70077)
                     /locus_tag="ACL70N_000337"
     CDS             complement(68023..70077)
                     /locus_tag="ACL70N_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGS0589219.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLILPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(70089..70343)
                     /locus_tag="ACL70N_000338"
     CDS             complement(70089..70343)
                     /locus_tag="ACL70N_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589220.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(70336..70893)
                     /locus_tag="ACL70N_000339"
     CDS             complement(70336..70893)
                     /locus_tag="ACL70N_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0589221.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(70877..71833)
                     /locus_tag="ACL70N_000340"
                     /pseudo
     CDS             complement(70877..71833)
                     /locus_tag="ACL70N_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            71925..72284
                     /locus_tag="ACL70N_000341"
     CDS             71925..72284
                     /locus_tag="ACL70N_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGS0589222.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKLSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            72496..72741
                     /locus_tag="ACL70N_000342"
     CDS             72496..72741
                     /locus_tag="ACL70N_000342"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589223.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEEHHFYAF
                     YHAFDRPSYHLKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            72809..73216
                     /locus_tag="ACL70N_000343"
     CDS             72809..73216
                     /locus_tag="ACL70N_000343"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589224.1"
                     /translation="MEENDREILRQTSRTDTGLFSRRNPPLLIKYAMFDKKQKRGHKQ
                     SAKNLANWHYNDKEDSYTHPDGWYYRFHHTKHQKTQTDFQQEIKVYYADEPESVPQKG
                     LYMNERYQNLKAKECQALLSPEGRQISLNARLM"
     gene            73213..73350
                     /locus_tag="ACL70N_000344"
     CDS             73213..73350
                     /locus_tag="ACL70N_000344"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0589225.1"
                     /translation="MKPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEM
                     K"
     gene            complement(73598..80284)
                     /gene="bgaA"
                     /locus_tag="ACL70N_000345"
     CDS             complement(73598..80284)
                     /gene="bgaA"
                     /locus_tag="ACL70N_000345"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGS0589226.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGKERIFT
                     VINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEADQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
BASE COUNT        23989 a        17346 c        14419 g        24677 t
ORIGIN      
        1 gacgctcaaa ccattgtcgc gtctaaaaat aaaatctcaa ttcaagaaga caagaaagcg
       61 ttttaaaacc agtagacctt ttcataaggt tcgcttgatg taccaagatg aagctggttt
      121 cggtagaatc agtaaactgg gatcttgttg gtctccaata ggagtaggtc cacatgtcca
      181 tagtcactat atacgagaat ttcgctattg ttatggagct gttgatgccc atacaggcga
      241 atcatttttc ttaatagctg gtagatgtaa tactgagtgg atgaacgcct ttttagaaga
      301 gctttcacaa gcttatccat atgattattt tttactcgtt atagacaatg ctatatggca
      361 taaatcaagt accttaaaga ttccgactaa tattggcttt gcatttattc ctccatacac
      421 accagagatg aaccccattg aacaagtgtg gaaagagatt cgtaaacgtg gatttaagaa
      481 taaagccttt cgaactttgg aagatgtcat gaatcaactc caagatgtca tacaaggact
      541 ggagaaggag gtgataaagt ccatcgttaa tcggagatgg actagaatgc tttttgaaag
      601 cagatgagta ttatatgcaa tttctttata taaaaagacc ggattgctcc gatctttcaa
      661 tagttcatat tctcaatttc tattttaaaa atagctaagg ttaacgtcaa atgactacgc
      721 gacctatttc atacgataaa aatcaagcac tagaccagca ggtccttgaa ctaataagga
      781 ctctgttccc caatcggtta cagttggtcc gtgtaaaacc tttataccaa gctcgttcaa
      841 ccgtttgtag ttctggtcta catcctcaac ctcgatatga ataatgattc ctgactgaaa
      901 gttttccaaa ggaaccaaat gattttgtga caacataagg cagtgactac caatcgtaaa
      961 ctgagcaaaa ccatcatcag cataatctgc ctttttatcc aaaatatgct ccaagtcagc
     1021 acagacttgg ggaacatttg aaacgataat atctaattga tttaaattca tttactctcc
     1081 tccataaaaa gaccggattg ctccgatctt ttaaagttct gctctatgaa aatcaaagaa
     1141 taaagtctac aagtttcata tttgattttc ggcgagagga attatttaat tgcgcgtgat
     1201 tgcaatcctt cttcttccaa gaagagacgg aatggtacga gttcttctgc ttcgtatttt
     1261 tccttgaagg ctttgatagc ttcttctgag tgaagttttg gatccaattc aagtacttct
     1321 actggaagtg gacggtgttg agtgatgcga gcatcgatga caacagtttt accttctttg
     1381 ttcaatttaa cagcttctgc aacaactgca tcgatgtctt cgatacggtc aactgtgaat
     1441 ccaacagctc cttgagcttc cgcaatttta gcgtagtcag cgtttgtgaa gtctacacca
     1501 aacaagtgtt tgtttgtatc ttcgtatttg ttcttgatga agccgtactc agcatttgag
     1561 aagacaaggt tgataactgg aaggtcgtat tgaacgtttg tgataacgtc tgggtagcac
     1621 atgttgaatg ctccgtcacc catgatgttc catacttggc gatctggatt gtctttctta
     1681 gcagcgatac caccaggaag ggcaataccc attgtcgcaa agagtggaga tgtacgccac
     1741 atgttcttag gtgtcatgtg aaggtgacga gtagatgttt gagtagtgtt acctacgtcg
     1801 attgagtaga tagcgtcttg atcagcatgt ttgttgattg cattgtaaac ttgatacaat
     1861 tgcaattcac cctcagtttt accttcgagt ttgttcatgt aatcacgcca gttttggttg
     1921 ttcttaacgt ttgcacgcca ccatggagtt gattcaactg ggtttacttt gtcaaggata
     1981 gctttagctg cttgaccagc atcaccaagg attgaagcgt caagggcatg acgtttacca
     2041 agtttgtaag ggtcgatatc gacttggatg aatttttcag tgttcttgaa tgcttcgtaa
     2101 acttcagcaa atgggaagtt tgaaccaagg aaaagaactg tgtctgcttc aaagaccact
     2161 tcgttggctg gtttccaacc aacacggtaa gcagaacctg tcaaaccttc atagttccat
     2221 tcgaaagctt caaagttttt accagttgtg atgattggtg ctttgatttt acgtgacaat
     2281 tcagtaatca cttcaccagc tttaacacca ccaaatccag catagataac tgggcgttca
     2341 gcattgttca agatttcaac agctttgtcg atttcaactt cgttcaaagc aggagcgatg
     2401 aatgagcgtt cgtatgaacc tgaaccgtag tatgagtttt catcgatttc ttggaaaccg
     2461 aagtttactg gaatttcaac aacagctgga ccttttttag aaattgcagc acggcaggct
     2521 tcgtcaatta cttttggcaa ttgctcagcg taagctacac gtttgttgta aacagcgata
     2581 ccgttgtaca ttgggttttg gttaagctct tggaaagcat ccatgttcaa ttcgttaact
     2641 ggacgtgatc caaggatcgc taggaatgga gtgttatcca tagctgcatc gtaaacaccg
     2701 ttaatcaagt gagtcgcacc tggaccacct gaaccaactg caaccccgat tgagccgccg
     2761 aatttagctt gcataaccgc tgcaagagca cctgtctctt cgtggcgaac ttgtaagaag
     2821 cggatatctt tgtcttcagc caaagcgtcc atcaatgagc tgagtgttcc tgatgggata
     2881 ccgtagattg tatctacgcc ccatgttttc aatacgttaa gcattgctgc agatgcagta
     2941 attttccctt gagtcataat gataactctc cttcaatttt tttaaacttg gagaatacga
     3001 ttacatagaa ttggaaacgt tctccaaatt tttactattc cactgtatca tatttatgct
     3061 gacttttcta aaaatctgct caaaactctc tattctctat tctaatacag ttttgaaagt
     3121 gttgtcgttt ctgttttata acaaagaaat ctagtcatta cttttagtct attttactaa
     3181 aatttaacag aagggaactg gtcagaacag atacagaact aaaggccatg gctagacctg
     3241 ccaattctgg gttgagagcc agtccaacac ctgaaaagac tcctgctgca atcggaattc
     3301 cgacaacatt gtagataaaa gcccagaaaa gattgagtag aattcgatga aaggttttct
     3361 tactcatatc aaaggcacga accactccta aaagattatt ggttgtcaac accaaatctg
     3421 ctgactcgat ggcgatatct gttccagcac ccatagcaat tcccacatct gctacactaa
     3481 gggcaggagc gtcattgata ccgtccccaa caaaggctac tttacctgac tgttgcagtt
     3541 tatggatttc atgggctttt tcttctggca agacgcctgc aatgacctct tcaattccga
     3601 tttgatctgc aatagcacgc gccacaccag cattgtctcc tgtcagcatg actgttcgga
     3661 gaccacgttt ttttagctga ctgatggcta gcttagcatt ttccttagga atatcttgca
     3721 aagcaagcaa gcctttgatt tcattgtcaa cagctaaaaa cacaactgtc ttagcttctt
     3781 tttctagttc ttctagttta tcttgataag tattagaaat atccatgcca tccagcattt
     3841 tagcatttcc aagtaaaact tgttttccat tgattcgccc tgaaacacct ttcccgtgca
     3901 aggcctgaaa attttcaaca gtttgaaact caagtccagc ttcactcgct cgcttaacga
     3961 tagcctcagc cagtgggtgt tgagaagcat cttccaagga ggctgccaat ccaaacactt
     4021 ctacttcgtc gccgatgata tctgttacca caggtttccc ttccgtcaaa gtcccggtct
     4081 tatcaaagac aagagtttga actttctgga tttcctgtaa gacagttcca tttttgagga
     4141 gaacccccat cttggcacta cgtcctgtcc ccaccataag ggctgtcggt gttgcaagtc
     4201 ccaaggcaca aggacaggcg ataatcaaaa ccgccactcc gtagagaaga gaggacacaa
     4261 agctagctcc aagcacaacc acactatccc tgagcaagac gaaccaaacc caaaaggtca
     4321 tgattcctaa aatgacaact actgggacaa aaatccctga aatcttatcc gtcaagtcct
     4381 gaatcggcgc acgacttgtc tgagctttct tcacaaaatc cacaatctga gccaaaacag
     4441 tctctgagcc aactttttct gctctaaaga caagcgttcc actatgattg atggttgagc
     4501 caatgacagt atctccaact gtcttgtcca caggcagact ctcacctgtc accatggatt
     4561 cgtcaatact agagacacct tctactacga caccatcaac agcaatcttt tcaccgggac
     4621 gcactcgaat caggtcgcct accttgactt gttccaaagg aacttggaca taactatcat
     4681 cactcaagac ttctgcggtt ttagcttgca agtccagtaa tttctccaca gcttgggacg
     4741 tattttttct cattttttcc tcaaaaactg ctcccaaaag aacgaaaaag aggataaatc
     4801 cagcactttc gaagtaaaca gggagaccag caaagagagc aactaggcta tagaaataag
     4861 ccactagagt tcccagcgca accaaggtat ccatgttggc attgtgcttt ttaaaactgg
     4921 cccaagcact ctggatatat ggcttacctg caactaacat aataggcgtt gttgctagaa
     4981 aggttcccca atgcatgact tgatgactaa tgctacctgt caacatccca atcatgagaa
     5041 tcacaagagg cacagtaaag atactaataa tccaaaaacg ttgcaggaga gatagagatt
     5101 ttcgagtctt ctcaacgact gtatagcttc ccttttgcat cttcatgcca caagaaaatt
     5161 catgtcgccc taattcttga ggtgtaaaac gaatgacttt ctcctcatct acgccgattg
     5221 gttccaagat accttcttct tcaaacagaa tttccttata acagtttgaa ggagtagcac
     5281 gatgaaaggt aatctcagct ggaattccct tttgaagctg gatatgggtt ggatgatagc
     5341 ctttttcagc tcggatacgg attttttgaa tgccattttc taagcttgct ttcacaattt
     5401 ctgtcatagt ctccacctac tctacaatca tcttgccgtg catcatgttc ataccacaag
     5461 caaagccaaa ctctccagcc tgctcaggcg tgatttccac tacatactct tcccccattg
     5521 gcaggttcgc atgtacacca aaatctggaa aaacaatttg atccagacat ggtgaaggat
     5581 ccttgcgatc aaagacaatg cgtgctggca ctgatttctt gaggacaatc aactcaggag
     5641 tatagcctcc catgacttcc actcgaatct cttggtatcc gtttttttgc tgggcttttt
     5701 gtccagattt ttcaggcttt ttgaaaaacc aaaacaagat aaacgcgata agggcaatac
     5761 aaataatggt tacaatacta tttaacatga cgtttccttt acatacaatt acatcttact
     5821 tctgttacag cacttgattt cttctctgaa atcacagctt ccaagtcttc caagtcagtc
     5881 tgagtaaatt cacattctac aatcaagtca gccaacaaat tcctaatcct acgggaacaa
     5941 accttgtctt tgatatcttg gacaagtaaa tcccgacttt ggtctagagt taaaagggct
     6001 gaataaacaa aggacttgcc ttcttttttc cgagtcaaac actctttctc aactagacga
     6061 gccaaaagtg tctgaaccgt ggacttggac cagtcaaacc gctctgccaa aaccctaatc
     6121 aaatccgtac tggtctgctc cccctgcatc caaataatct tcatgacctg ccattctgca
     6181 tctgaaatct gcattaccat acctccaaaa tctacatttg tcaattacac tcatcagtat
     6241 actcttaaaa tctacatttg tcaattatag aaataatatt ttcttcgaaa aatagaattt
     6301 taatcatttg aaaaacgatt tgcagtcaaa tattactata taaacaataa aaatatgcta
     6361 tactaaagaa aaaagaaaac aaccactagg ggtgcgtaaa gctgagatta acgactgtta
     6421 gatccctctg actcaatcta ggtaatgcta gctgatggaa gtggaaatga taatggggac
     6481 tagcagtctt ctattgcctt tctaaaacag actagcttgt tcttaagaat acaaacttca
     6541 gttggttggg aggttttaga tgacttattt acccgttgct ttgaccattg cagggactga
     6601 ccctagtggt ggtgctggca ttatggcaga tttaaagtca ttccaagcga gagatgtcta
     6661 tggaatggct gttgtaacca gtcttgtcgc tcaaaatacc agaggtgttc agctaatcga
     6721 gcacgtttct cctcaaatgt tgaaagccca attggagagt gtcttttctg atattccacc
     6781 tcaggctgta aaaactggaa tgttggctac tactgaaatc atggaaatca tccaacccta
     6841 tcttaaaaaa ctggattgtc cctatgtcct tgatcctgtt atggttgcta caagtggaga
     6901 tgccttgatt gactcaagtg ctagagacta tctcaaaaca aacttactac ctctagcaac
     6961 tattattacg ccaaatcttc ctgaagcaga agagattgtt ggtttttcaa tccatgaccc
     7021 cgaagacatg cagcgtgctg gtcgcctgat tttaaaagaa tttggtcctc agtctgtggt
     7081 tatcaaaggc ggacatctca aaggtggtgc taaagatttc ctctttacca agaatgaaca
     7141 atttgtctgg gaaagcccac gaattcaaac ctgtcacacc catggtactg gatgtacctt
     7201 tgctgcagtg attactgctg aactagccaa gggcaagagt ctttaccagg cagttgataa
     7261 ggccaaggcc tttatcacaa aagctattca agatgcccct caactcggtc atggttctgg
     7321 tccagtcaac catacaactt ttaaagatta agaaaaaaaa ctctctagtt cccactttaa
     7381 gggaattaga gagtttttat actcttcgaa aatctcttca aactacgtca gcttccatct
     7441 gcaacttcaa aacactgttt tgagctgact tcgtcagtct tatctaaaac ctcaaggcag
     7501 tactttgagc aacctgcgac tagctttcta gtttactctt tgattttcat tgagtattaa
     7561 ttaggaaaga atgtcatgca actttgttaa aaaggcttgc gtttttgcct caatatcttc
     7621 tgcttgcatc aaatcacgta caacagctac accagctata cccgtgccga taagttggtc
     7681 aatattctct gatgtcaagc cgccaatagc aactactgga atggcaaccg tttgacaaat
     7741 tgttttcaag gttgaaatca gggtgatggg tgcattttcc ttggtggttg tcggaaaaat
     7801 ggctcctgtc cccaagtaat ctgcacctga tttctccgct tccagagctc ttttaaccgt
     7861 tttagcggtg acaccgagga ttttttcagg acccaagact ttgcgagcta ccgaaactgg
     7921 taattcatca tctccgatat gcagacctgc tgcatcaacc gcaagacaaa catccaaccg
     7981 atcatcgatt atcaagggta cctgataagc aactgttatt tccttgactt gttttgccag
     8041 ttgataatat tgattggttg tgagattttt ttctcgcaat tggactatgg taacccctga
     8101 acggcaggcc gtctcaactt ttgcaagaaa gctttccacg gaatcttgat agcgattggt
     8161 taccagatat agtctaagtg cttctctatt cataaacctc tcctttgatg gtatctagcc
     8221 aattttcatc tcttcttagg agcgaaagct gattgagtac ttggtaacga aattcttcca
     8281 atcccattcc ttgaacaact attttctcag cagcgatatt gagataagag actgctaagc
     8341 aagaagcttc aaaaccagtc tttccttggc tgagaaaaac ggctgttaag gctccaacca
     8401 aatctcctgt ccctgttatc cagtctaatt cagtacagcc attctccagt acagcgacct
     8461 gatttttcga aacgatgagg tccttggggc cagtaactaa gaatgacata ccaggatagg
     8521 tctgacacca atctttcaag acttgaagca aatcctccgt ttcttgatct ttagcactcg
     8581 catcgacccc aacgccgtgg tgctttaatc caacaagact tcgaatttct gacatgtttc
     8641 ctttaaggac cgtaggtcta tagtctaaaa ggtctttaac taagctctta cgaatggatg
     8701 aagtcgttac gccaaccgca tctactacca ttgggagaca aacttgagct acataagaag
     8761 ctgctatacg gattgctttc tccttctcag ctgacaaatg ccccaaattg atgaagagag
     8821 cctgactttg cttagtaaaa tcaagaacct cacggggatc atctgccatg acaggtttgc
     8881 atcccagagc caaaatccca tttgccagca tctcacaaga aatctcattg gtcatacagt
     8941 gaatgaggga actagagcct ataggaaagg gatttgtaaa ttcctgcatc agtctatcct
     9001 ttcactaaag aaatatccct gcactttttt aaagaattcc tgcttgatta aaaatcgaaa
     9061 ggcaataaag gaaatcgctg taccaatcaa ggttgctccg aaaaatcgag gcgtgtagat
     9121 aaaccagcta agcttagcag ctgatcctgt aaagagtacc ataacaggat aggaaacaat
     9181 agaaccaata atacctgttc ccacaatttc tcccaaggca gaaaagtaaa attttcgacc
     9241 gtacttataa aagagacctg ctagaagggc tccaaaagtc gctcctgtga gagctaaagg
     9301 cggaatccct tgagtcgtca tacggataat ggctgtcact gtagccatag ccaaggcata
     9361 aacaggtccc atcatgattc ccgctagaat attgactaca ctggacatcg gtgccattcc
     9421 ctcaattcga aagataggtg taaggactac atcaagggca atcatcatag ataaaatggt
     9481 taatttgtga acttgtaatt ggtgctttct catgtttcta ttcttctcct ttttctaaag
     9541 actgtaaatc gctcttccat gtctggtgtt ggtaggccat ttcccaaaac ttggcttcca
     9601 tatgaacact gatgtggaag gcatctagca ttttttgctt gtctgtctcg tcactttctc
     9661 gatagagctg attgaccagt gctccctcct ctctgatctg ttgctctaac tcatccgtaa
     9721 tataagtttc aatccattgt tgatagagag gatttggtga tggtttaaga ttaagtgatt
     9781 tgcctatatc atggtataac caaggacaag gaagcaagct tgcaaaagct atggctaagt
     9841 tcggttctgc aaattgccta taaatatgag aaatgtaatg ataacaggtt ggagcgattg
     9901 gatgttgctc catttcctgg tcgttgattt ccaattcctt gaaaaattgt tggcgaataa
     9961 ataactcacc ctccactaaa ccctgagcat tttgtttcaa aagtcttttc atctcttggt
    10021 ttgaagtctt atcagccaaa agatgataga tttctgagaa agccttcaga tagtaggcat
    10081 cctgaatcag gtaatagcgg aaaatggcag gttctaaatt cccctcttgt aattgtaaaa
    10141 taaagggatg atgaaaggaa acctgccaag ctttcttgga taattccatc gcaatatctg
    10201 taaattccat aataactcct ttataaaaat agactggttt gaagcaataa aaagaaaagc
    10261 aggtagatta attttgtttt tttaggaata taaaaagtcc gatagctatt cttcaactgt
    10321 gcatgttcgt catatccgtg agcagataga gctctcaggt aaagatggcg ccacctaaag
    10381 actgtcatca gaaccttact gtaaatcaag ggcgaccaaa aatgtagttc ttgaccacgt
    10441 aataggcaag cttctttgag ggacttgatt tcttgctgaa tgagaggaaa agaattgaat
    10501 accacaatca aggcatagga ccaagagcgt gatagcccct tttgagccaa gtacaagaga
    10561 agctctttta gtgaaataga ggaaacaaag acaaggccga tacaaactgt cacaaaggcc
    10621 ctcgttccaa gcatgactgc ctgtgaagca tctccgtgta actgaactgc ccagtagttg
    10681 gcaaaagatg gtaaaatggc aagtatgatc atccaagcta acattttaaa tcgacggtaa
    10741 tagagcataa agagaacaca aaatgcgact accgaaagat tcagagcaat cgaaggaatg
    10801 aaagatgttt ccaaggataa aatcagcaag aagagactga taatcggtgt ctgggttgct
    10861 actttgacca tactatctca cctccccttg ggtattgcta ctctgagatg taagtggttt
    10921 ggtaatggtc acttctttca catgccgaag accctgacta gtcatctcaa tccaataatc
    10981 aaccacagaa atcaaagggt ctaaacgatg actaatgagc agaaaacttc ttccttgatt
    11041 cctctcctcc acaatccact tgcaaaaata atggcaggct ctatcatcca aacctgcaaa
    11101 aggttcatct agcaagatca cggaagcctt actggtcaag atggtcaaga gctgaagaat
    11161 tttttgctga ccaccactta attgataggg actcttatcg actgcctgct ccaaatcaaa
    11221 atctcgtaaa gcttgaaaaa tccgctgatt tctttcagaa tcaggtccat ctaattgaag
    11281 ctcctctcgc agactgactc gaataaactg cttctcagct tcctgaacaa caccagtcag
    11341 atcacggtac aaactctttt tctttttcag gactgtcccc ttccatgcaa tgcgcccctt
    11401 atacttttga aattgaagaa tagagcgaaa gaaggttgat ttcccgacac cattgtcacc
    11461 caggatacag gaaatccctt gatagaatgt gaaatcagca attgaaaaga gggagcgatt
    11521 tccaaactca caagtcgttc tatccatatg gaatagttcc gggctagaag caacttcctt
    11581 tgaagcaacc tctgtcatct cataggaagg gatttgaaac acttccctta gttttccgtc
    11641 tcttagctca accatatggt cgatataggc tttatagtca gataaatcat ggtcgcacaa
    11701 aataactgtc ttcccatcaa gagccaactc ttttagaatc tccaatatct cgattctgct
    11761 cttgcggtca atggaagcga agggctcatc caagagatat accctaggat tcatggcaaa
    11821 gaggacagcc agcgctgctt tttgcttttc cccacctgat aggtgatgaa tgggacggtg
    11881 taagattgcc tcgcaacgac attgctggac aacctctgct attttagaat caatttcctg
    11941 aaggtgatag ccgatattct ccaaggtgaa aatcagctcc tcaaacaagt tctccatggt
    12001 aaattgatga ttgggatttt gaaagagaat gccaaccttc tggacacgtg cgatgataga
    12061 aagctgactg acctcgctcc catctatcag gacttgacca ctatagggag gagaactgac
    12121 ttgggcaatg acttgaaaaa ggctggattt tcctgaacca ctgctcccaa ctaacaaggt
    12181 aaaggcttgc gcatgaaaag taaaatcaaa cggctcaggg aagattggag actgaatcgc
    12241 tcgtagttcc agacccatct atgcttttcc tccagttgca aactgatgat agagtttgac
    12301 aatggcacga accaagatgg tacagaagaa ataaacagaa ataaaacgta ccacaagtaa
    12361 ggaaaggaca aacggaaggg aaaaggcgta gtaacctaac ttaatgtatt catagacaaa
    12421 gctaacaagc gtaatcccaa tactattagc agttagagag agccaacttt catagcgatt
    12481 cttagttacg ataaaaccaa attcacttcc caaaccttga accaagccag acaaaagagc
    12541 tcctagacca aattggctac cataaaggac ttcagcaagc gcagctagca cttctccaat
    12601 cgttgcactt ccgactctcg gaacaaagat ggcagcaatg ggcgcagcca tacaccagag
    12661 accgaagagg atttcattgg caaaggcctg caaaccaaga ggtgttaaga gtagactgag
    12721 aatattatac acatatcctg aaccaacgaa aaccccacca aaaaagatag acaagaaagc
    12781 aagcaagata acatctttta actgccattt tttcaacata aaaaactcct tttttaaaag
    12841 aaaagtgggg cactcaagaa gaccgaccta aatactttgt atagcagatt gattttagaa
    12901 cagtacacag gaatgctaaa atatttctag aaattaattt gaattttcta attgatttgt
    12961 tcgcatctta tttcaatcta ctatatcatc ttcatccagt ttcgtaaaag aaaaaactct
    13021 aattacagat acgaattaga gttcagctta caagattaga cagttctttt cgacatacga
    13081 aaaaaacatt tcacatttcc cttcgccagt cttaactgta tcaggttcaa tgggtatcat
    13141 ctcagcctaa agcaccccaa atgcctttat tatttaatta tgtgattatt ataacacaca
    13201 ttttatacta gttcaagaaa ttgaactgga aatacagcct tgcactcaca aagacagcag
    13261 atctttcttt tgcaaaaaat aaatgacctg tttgatgaat tagccattca agctgaatct
    13321 agacatagtt ttttaaaaaa ggaaaatcct acttacttag aatccaagga tagatatcta
    13381 ttgttcactc atttcccgaa cagttttttc tatatttttt gcatacgata ttgccgaaat
    13441 gattgaaacg ccatccatat tggtctttat aatgtcttta atatgtttcg tctgtatccc
    13501 accaattgca actaaaggca tttgtggcaa tagttttctc atcaattcaa gaccttcata
    13561 acctatagca ccaccagcat catcctttga ctgggtatca aatacaggcc caacaccaac
    13621 ataatctaca tattcaactt ttgattgttg aaattcttcc tcgtttttta tagaaagacc
    13681 aattatttta tctggcatca attttctaat ttcatcaaca ccaatatcat cttgacctac
    13741 atgtacgcca tcggcgtcaa tttccattgc caaatcgata tcgtcattaa cgataaatgg
    13801 aacattgtat tttttacaaa gttctttaat ttggatagct agctcaagtt tttctaagcc
    13861 ttctaaagca ccctcacctt tttctcgaaa ttgaaataag gttataccac cttttaaggc
    13921 ttcctcaacg actgtatata gatcttttcc ttggcaagta gtcgttccac aaataaaata
    13981 tagttttagt aattctttat gaaacatctt acttcactct tttgaatttc ttgacatctt
    14041 catctgtaat ttcatataag gcatttataa attcaacttt aaatgttcca ggaagatgtc
    14101 catttggacg tttttccgcc atttctccag cgatattgta aaccaacatt gctgtttcta
    14161 atgatttcaa ttcttgacct ttttcaagtc cgataaagct tgctactaca gctcctaata
    14221 agcatcctgt cccaatgact ttcggcatca tagcactacc attatgaatc gttaccactt
    14281 ctccattaac agcaatggca tccacttcac ctgttactac tattggaata ttgaacttct
    14341 catttgctgc tagagcaatt tcgtcaatat tatctacgcc cgcactatct actcctttag
    14401 atgccacatc tattcctact aaagaggcaa tctcgccagc atttcctcta atcgctgcta
    14461 gtttataatt gttgattaga tcatctgcta ctttttttct atattctcct gctccacagg
    14521 ctacaggatc taaaactgct gggacattat atttctccgc aattttcaga gcagcttggt
    14581 ataatttcca attttcatct gtcaatgttc ctatgtttat taataaacca ccagcatact
    14641 ttaataagtc ctctaaatct gctggaaact cactcatggc tggtgaggcg cccagtgcta
    14701 ctaatccatt tgctgtgaaa ttttttacta catcattggt gatgcaaatg accaaaggtg
    14761 ctttttcttt taataatttt aaacttgtca tattgaaatc cttccttttc actttatacg
    14821 atctactaat ttcgatttat ctttagttga gaattttttt catttacatt gaatgattta
    14881 tactcaatga aaatcaaaga gcaaactagg aggctaaccg caggttgctc aaaacactgc
    14941 tttgagcctg tagataagac tgacgaagtc agctcaaaac actgttttga ggttgtggat
    15001 agaactgacg tggtttgaag agattttcga agagtcttac ctcatcaaat ttgtaaatat
    15061 catgagcctt ctctagacat cgtaaccaat atcaaaaaaa gctaattcta aagcgactgc
    15121 ttgattccag cgttgctgaa gttctgtcaa atcttctcga tttttaccga cacgattgag
    15181 ttcgtcaacc agaaattgaa cccactctgc aaagaaagga cctctgtgga gattgatcca
    15241 ttccgaatga atatagactt caggtagagc caaatcttta gaaccccagt ctaaatagag
    15301 accttctgca atgaccagca taaccaaaag atgggcatag tctgatgaag ccactgccga
    15361 atacattaga tcctgaaagg cttttgttac agggtgcaaa gtcacttcta gatagtcatt
    15421 ctctgctact tttaactctt taaaagcctt ttggaaataa ccatcttcat ctgcttcaag
    15481 aaagcctagt tgcttggcaa aacgaagctt ggattcaagt ttatctgcgt gagctacgca
    15541 ggcacccagc atggataaga aggcatcaaa gaagtgataa tcttgaatca gatagtcctt
    15601 taagacctta ttctcaattg tccccgcaaa aagttcctta acaaaacgat gattgattgc
    15661 agcctgccaa tccttctgac tgctttttaa taattctcca acagtcaaac ctggctgaaa
    15721 tgcatagtct tgtgtttcca tatttacttc tcctctcttt acttgttagt aattaataaa
    15781 acagcaagaa atatcaagca aaatcgtaat tccacttgat ccttttaaag cacatcgaga
    15841 gcatttgcag agagctaact aaacaagcct atccagttta tataaacaaa aaactccaat
    15901 tacaatcaag aattagagtt gacttacaag attagatcgt tcatttcgcc atacgaaaaa
    15961 acgtttcaca tttcccttcg ccagtcttaa ctgtatcagg ttcaatgggt atcatctcag
    16021 cttaaagcac cccaaatgtc tctattattt aattactgaa ccagtatagc aaaaaatgaa
    16081 agccctagca agatatttga ccgaaaaata tctttatata gtatattgaa actagaatag
    16141 tacacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat tgatttgtcc
    16201 tattcttatt tcattttact atagttttcg atagcaattt attcttccaa tacacgaaga
    16261 aaaacctcca cattcagtgg aggcaatctc ttttatcaat acaattttaa gtcacgaggg
    16321 tcaactggga aggttgggtt gtatggattg tgacggagct taaagtgttt gacatcttca
    16381 atggtctgag ctccagacaa ttgcataact gtcttcaatt ccgcattcaa gtgttcaaag
    16441 acttgacgca caccgacact accaccgaga gccaagccat aaataacagg gcgaccaata
    16501 gctaccaagt ctgctcctga agccaaggct ttaaagacgt gttgaccacg acgaacacca
    16561 gagtcaaaga caatcggcac acgtctatca actgcttctg ccacttcttg aagcgagtca
    16621 aaggcagctg gtccaccgtc gatttgacga ccaccgtggt tggttaccca gataccagaa
    16681 gctcctgcag caagtgaacg ttcaacgtcc tcacggcatt gtggtccctt gacatacaca
    16741 ggaagaccag agtattcagc gataaattct acatcgcgtg gagacaagcg ttgtttagct
    16801 gatttgtaaa caaagtccat tgatttacca gcaccttctg gcaggtattc ttcaacaatc
    16861 ggcatgccaa ctgggaagac aaaaccatta cgcttatcca cttcacgatt cccccctaca
    16921 gtagcatctg ccgtcaagac aatcgcttta taaccttcag ccttcacacg gtccatgatg
    16981 tggcggttga taccgtcatc cttactaaag taaaattgga accaatgggg tgtcccttga
    17041 agggcttcag aaatctctgg aaggtcaaca gtagagtaag agctggttgt ataaagagaa
    17101 ccaaactcat gcacaccacg cgcagtcgcc acttccccct gttcatttgc caatttatga
    17161 gccgcaacag gcgccataat gattggtgaa gatagttttt cacctgcaaa ttcaatctct
    17221 gtacttggat tttcaacatc gcaaagtgta tgaggaacga tgagtttgtg gttaaaggcg
    17281 cggatattct ctcttaaagt gaaagtatct tccgccccac tagcgatata gccaaatgct
    17341 gctttaggaa taacttgttg cgccattggc tccaaatcat aggtattgat gaagtctaca
    17401 tgaccttctg cattgcttgt tttgtatgac ataaaatgcc ctccttgatt aagtaagcgt
    17461 ttgcttttta ctacacaact ataataactc ttttttcaat cattttcaag agttttgctt
    17521 aaaaaccatc ttattttttc atacaatata ctagccctac tttccttaaa ctctaaactt
    17581 tagtctatat taagtgaatc gttgagattt tttgctgcca ggcatttgaa ctactttttt
    17641 atttgcggat tctatctact aatactataa aaaaacaagt gaataagaca ccagaacatc
    17701 ctctaatagg acctatggac ttatatcagt cccatatata ctgtttaagc aagatactat
    17761 cctagttgac gctaacttcc tatcccactt attaattttt tatttatagt gaatctgaac
    17821 aaatcaattg gggaatccaa gtcaatttct agtacttttt gaacagtttc agcgtactat
    17881 cgtaaaatga aataaaacat gcacaaattg cttagggaat ttaaaccaat ttctaacaat
    17941 gtcttagaaa tcaaagtgta ctatttcaac ttcaatatac tacacttcat tttctcctta
    18001 aattcagtct ctttttgaat caaaaaatcc cctggtaaga gccagaggat aagaatttat
    18061 ttcattgttg ggaagagcaa tacatcacgg atagttgttg tatcagtgag gagcatgcag
    18121 agacggtcga taccgattcc caaaccacct gttggtggca taccgtattc aagagcttca
    18181 atgtagtcat agtcgattcc tgtcgcttca tcatcaccaa gttctttggc tttagcttgg
    18241 gcttcaaaac ggctaagttg gtcgattggg tcgttcaact cagtaaaggc attaccgtac
    18301 tccttagtca tgataaagag ctcgaaacgg tcagtaaagc gttggtcttc aggatttttc
    18361 ttagcgagtg gagatacagc tactggatgt ccatagacaa aggttggttg gattaaagtt
    18421 tcttcaacaa actcttcaaa gaaggcattg atgatgtgac caacctcagt gtagtgtttc
    18481 tcaactggaa ctttcttctc agcagcgata gttttagctt cttccaaagt catgtcttgc
    18541 cagaaatcga caccagtaat ttctctgata gcatccacca tatgaacacg cttaaatggt
    18601 tcgttaatct tgatttcagt accttggtag ttgactgggc catcgccttt gactgattta
    18661 gcagcatgtt ggataatgcc ttccgtcaag tccatgatat cttggaagtc tgcataagct
    18721 tggtaaactt cgatagaagt gaactcaggg ttatgagtag cgtccattcc ttcgttacgg
    18781 aagatacggc caatttcata gacacgttcc ataccaccca caataaggcg ttttaagtga
    18841 agctcagtcg cgatacgaag caccatgtca atgttttggg cattgtggtg ggtgataaat
    18901 ggacgggcag cagcaccacc ggcttcatta tgaagaacag gtgtttccac ttcaaggaat
    18961 cctttttggt caaggtaacg acggatttca gagatgattt ttgaacgagt gacaaagcgt
    19021 tcaaagcttt cacgattaga aatcaagtca aggtaacgtt tacggtaaat tgtttcaacg
    19081 tctgtcaaac catggaattt ctcaggaaga ggacgaagag ccttagacaa gtgtgtgatg
    19141 tgggttgcct tgatagagag ttctcccata tccgtacgca tcacttcacc ttcgacacca
    19201 aggaagtcac caaggtctgc ttttttgaag atttcgtagt tttcttcacc gacagcatcc
    19261 ttacgaacat agatctgaat ctggccttcg cggtcttgaa ggtgggcaaa accaactttt
    19321 cctttaccac gtttggttac caagcgtcct gcgatagtag ctgtttcgtt tttatcgtgt
    19381 aattgttctt tatcgaggtt ggcatattta tcttttaatt cttgtgaatt tgcagtacgt
    19441 tcaaaacgtt ttccgaaagg atcgattcct tgttcgcgga gcgcagccat tttttcacgg
    19501 cgaacgatct gctggtcatt tagttcttcc atatgttctg tagacatggg atcctcctag
    19561 ttttactcaa aattgaatac gatgagtcat tttttgcgat actcccattt tatcataaat
    19621 aagcaagaaa ttcacggata atctttaaaa actaaaaaga acctgacgct aaaatcactg
    19681 gaaagaagtg aaagtatctt ccgccccact agcgatatag ccaaatgctg ctttaggaat
    19741 aacttgttgc gccattggct ccaaatcata ggtattgatg aaatctacat gaccttctgc
    19801 attgcttgtt ttgtatgaca taaaatgcac tccttgataa gtaagcgttt actttgtata
    19861 ttgcagtttg gggaagtttg ggatcctttc tgctcggttt aatcgttagt atcatccgac
    19921 attatcgaat ccctgttttg gcgcaagtag cgacagccta cattgaattg tcacgtaata
    19981 cgcccctttt gattcaactc ttctttctct acttcggtct tccccgaatc gggattgtcc
    20041 tatcttcaga agtctgtgca acgcttgggc ttgtcttttt aggaggctcc gccatgcagg
    20101 attcgggaat ccaagtactc tttcaaggaa ataatctcct gagaatctta cagggattgg
    20161 gcgttacgat tgggatatcc atcctgtctg tcctcttatc catgatgttc ggaacagtca
    20221 tgggaatcat catgacctcc cattctagaa tcatacgatt tttaacacga ttgtatctgg
    20281 actttacccg tatcatgccc cagctggtgc tactcttcat cgtttacttt ggcttggctc
    20341 gaaactttaa tatcaatatc tcaggtgaga cttcagctat tatcgttttt accctctggg
    20401 gaacagctga aatgggagac ttggtacgtg gagctatcac ttctctccct aaacatcagt
    20461 ttgaaagtgg acaagcactc ggcttgacta atgttcaact ttactaccac atcatcatcc
    20521 cacaagtctt gagaagactg ctaccgcagg ctatcaatct tgtcactcgg atgattaaaa
    20581 ccacttcatt agttgttttg attggggttg tggaagtgac caaagttgga caacaaatca
    20641 tcgatagcaa tcgcctgacc atcccaactg cttcattttg gatttatgga accattctag
    20701 tcttatattt cgcagtttgc taccctattt ccaaactatc cactcactta gaaaaacatt
    20761 ggagaaacta aatgtctgaa actatcttag aaatcaagga actaaaaaaa tccttcggag
    20821 acaatcccat cctccaagga ctttctctag aaattaaaaa aggggaagtt gttgtcatcc
    20881 taggggcatc tggttgtggg aaaagtaccc tccttcgttg cctcaacggc ttagaaagta
    20941 ttcaaggtgg agatattttt ctggatggtc agtctatcgt tgaaaataaa aaagattttc
    21001 acctagttcg ccaaaagatt ggcatggtct ttcaaagtta tgaactcttt ccccatctgg
    21061 atgtcttaca aaacctcatc ctaggcccta tcaaaactca aggaagggac aagaaagaag
    21121 taacggaaga agctttgcaa ttactagatc gtgtcggttt gctggataaa caacatagct
    21181 ttgcccgtca attatctggt ggacagaagc aacgtgttgc aattgtccgt accctcctaa
    21241 tgcatccaga aatcatcctt tttgacgagg tgactgcttc gctggattca gaaatggtgc
    21301 gtgaggtgct ggaacttatc aatgatttgg cccaagaagg ccgtaccatg attttagtaa
    21361 cccacgaaat gcagtttgcc caagccattg ctgaccggat tatcttcctc gaccaaggga
    21421 aaatcgctga agaaggaaca gctcatgcct tctttaccaa tccgcaaacc aaacgagccc
    21481 aggaattttt aaacgtcttt gactttagcc aatttggctc atatctataa aggagattct
    21541 tatgaaacta ttcaaaccac tcttaactgt tttagcactt gcctttgccc ttatctttat
    21601 cactgcttgt agctcaggtg gaaacgctgg ttcatcctct ggaaaaacaa ctgccaaagc
    21661 tcgcactatc gatgaaatca aaaaaagcgg tgaactgcga atcgccgtgt ttggagataa
    21721 aaaaccgttt ggctacgttg acaatgatgg ttcttaccaa ggctacgata ttgaactagg
    21781 gaaccaacta gctcaagacc ttggtgtcaa ggttaaatac atttcagtcg atgctgccaa
    21841 ccgtgcggaa tacttgattt caaacaaggt agatattact cttgctaact ttacagtaac
    21901 tgacgaacgt aagaaacaag ttgattttgc ccttccatat atgaaagttt ctctgggtgt
    21961 cgtatcacct aagactggtc tcattacaga cgtcaaacaa cttgaaggta aaaccttaat
    22021 tgtcacaaaa ggaacgactg ctgagactta ttttgaaaag aatcatccag aaatcaaact
    22081 ccaaaaatac gaccaataca gtgactctta ccaagctctt cttgacggac gtggagatgc
    22141 cttttcaact gacaatacgg aagttctagc ttgggcgctt gaaaataaag gatttgaagt
    22201 aggaattact tccctcggtg atcccgatac cattgcggca gcagttcaaa aaggcaacca
    22261 agaattgcta gacttcatca ataaagatat tgaaaaatta gcaaggaaaa cttcttccac
    22321 aaggcctatg aaaaaacact tcacccaacc cacggtgaca ctgctaaagc agatgacctg
    22381 gttgttgaag gtggaaaagt tgattagtca ttaactctta aaaggaactg gattttaagc
    22441 tccaatccct ttttaagatt ttacctataa catcctgagt ctatctaaga tgttcaatct
    22501 gaacacagtg tacatacttt atcttctatt gcatatactt tatcacataa gatacgaata
    22561 tcctcttcac tatgactagc aatcaaaatt gttgtccctt tttcactaga gagctttcta
    22621 aacaatgttc tcatattttc tacacttgat ttatccaagg cattcatagg ttcatctagt
    22681 aaaagaatag agggattctc cataattgct tgagcaatcc ctagcttttt cctcatacct
    22741 agcgaataag ttttaacttt ctggtctttt tgctcatata gaccaactat tttcagtgta
    22801 tcattgattt cctgattacc aactactcct cgtatgcttg ccaaatattg taaattctta
    22861 aagccactat aataatttat aaaaccaggt tcttcaatca aagctcccaa attagctgga
    22921 atttttctct caggaacaat attttcccca ttgattaaca cttctccata agacggacta
    22981 tataaaccag ctattaattt aaacaataca cttttacctg agccattcgc accagtaatt
    23041 cctataattt ccccctgttt acaactaaaa ttaaggtttt gaaaaacaca tgtttttttt
    23101 aatttcaact caatattttt taatgtaatt atttcattca ttctataaac ctcctctttt
    23161 gacgagtgaa atagaaaatg cttttaaaaa gaaagactaa aaatagcaac tgaagaaata
    23221 aatctcgtcc tatatctcca ttccctcgat tcaaaatata aaatagataa ttagttcgat
    23281 ttcctacaaa tagaccacca aacacaatca tgagtaaaaa gaaactaacg caagcaaagt
    23341 tcatttgtac attcgctcct agtgcgtata acataaagca aagcaaggat agcacacaag
    23401 cattcaaaga atcaactata aacaaaactc ctatatccca gtttgctaac tgtaacataa
    23461 attgaatcac tagaactttt accatgatta aaatgagtcc ataaagaaaa caggtccaaa
    23521 tctgatacct aatccagagc ttaatagaag aaaatcgaat cacttccata aagaaatcgg
    23581 atgctcttct acgatataca actgctagaa aaaatgtatg aataataaac caatgaagca
    23641 accatataga taagactaaa aaagagtttt gactcagatt aggccctttt aaaatttcta
    23701 taacaagtct atcatttcct tctaaccaat accataatcc taaacaaatc aatatccaaa
    23761 aaagaacata accccaaaag tacttggtat agattatctg attcaacctc cacatgtgac
    23821 tacttaactt tcccatttcc aacttttaca ctctcctcca gtttctatga acagaaaata
    23881 cagtcaatgg aattatgata gatagtaatg taagccaata aatcaatgca tacggattgg
    23941 aatttaccat atactgaaaa attggcaata atccaattat cccattgttc aactgataaa
    24001 tccagaataa ggattctaca aataaaaaag taaacagaaa tactaagctc atgtttgatt
    24061 ttttaaacca agaaaaactg ctaatagtaa gtaaggataa aaagaaatag tatgctatat
    24121 aagagaaaaa aaatcctata aagaaactag cattgtttgc aatacttata ccataaaatt
    24181 ctcttaaaaa atcaacctcc tttatctcca aagagaagct aaaaccatta ctaaatgcaa
    24241 ttagaaaaat caataaaaat aaagtcgccg tccaaatccc cgtactaaga gctgctaatt
    24301 tgaaactaaa actggtaaag tgcttaattg atttcagacg aatgcgacac tccaacctat
    24361 taaaatagtt attcatcaaa taaaaaaaga acaatatata tgtgaacgga aagcaatata
    24421 ctccagtcgt catatcttga agtaaaacta aaatccattc taatacattt ggatggattg
    24481 aatattggcg acagcgcaat aaatatactg tactagataa aacacaggat agcagtaata
    24541 taaaataaac caatactgct aagaaatctt ttttataaaa ttgaacaaat tgtttcatta
    24601 tacatagtcc tctgaatgta gaaaaaatgt accataaaca accaaacaac taacaaataa
    24661 aataaaagca agatgcccac taactaagga aagactgata tctttctgat atcccaaagc
    24721 tagcgttgtc acaggttcta agtaagatag ccctaaaata gcccataaaa taccaccaac
    24781 caccatatag gcaactggga tgaaaatagc tcctaatttt ttcttcacta gcaaagcact
    24841 agctagtcca aaaatagaga acacagcgcc ccaaactcca taccagagag tcgtcacaag
    24901 actatagaga aactgattag aatcaaataa ttcttttaag gcaccactat aatctccaat
    24961 ataaatttcc tgataaggag tcactaaaag attaattcct aataataata aataggggag
    25021 aaaaaagact agaaaagaag aaataattgc agtactacct acaatagcta gatacctctt
    25081 tttagaaatt cggcacaatt gtgctgttag aaaatgactc tcagcatcct ctattatctg
    25141 actagaatag ggcagtgtac agataagtgc agctactagg ctaatcggtg aaaatcctcg
    25201 aatagaagaa gcggcaaaaa aaatcgataa accttcaatt ttataaatac cattgaaagc
    25261 aaggaaattt cctaaactca tgcaaagaag ggtcaaaaat aaagacatat aaaaccgagg
    25321 tgattgaacg actcgtacaa gattacaaat gaaaaattcc atccttactc ctccttataa
    25381 taaaaatagg gtgtagcatt cttttttcat gctacaccca caatcaacca tctttaaggc
    25441 ttactctgac aagtaagtta ataagaatct ggactccaag aacctgaagt atgaattctt
    25501 acatgatttc caaattgtgg cgccatagct aatctagtac cagaaccaat ataattgtca
    25561 ccacctccat tatagtacat gacaatccta gagccagacc ccaatgaata taccggggta
    25621 atatctgacc cactataggc gctacgaata gaggtattta accttttacc gccaccagtg
    25681 ctgtcactat tattaattcc agcagaggcg ttttctttct caagctcact agttgtatcc
    25741 gaaccccaac gcggcaacgt taaatcataa tttccaatct gtctagctaa aactgtaggg
    25801 agaaacaaac tagatgcaat tgtaactacg caaaaaagga atatattttt cttcttttca
    25861 tgacatcgtc ctcttaagaa gtgataaaca agatagttga ttgatcaatt tgatacatat
    25921 tacattttca ttatatcaat aaaagaaagc gttgtcaatt attttattta aaatattatc
    25981 atattttaaa taaaatggta aaagagactc ggtagcctcg tctctcttta tcttactgac
    26041 ctaaccttct tgccaatttt cttggtcttc tttaaagcgt tttagaagat caaggccctc
    26101 tggcgtgatg taaccttctt cttgggctag atggataagc tcgctatagt ttgaaagcgt
    26161 cacaagttta acaccagcat ctgcaaagtt cttatctgct tttggcaatt ggtagctgaa
    26221 aatcgctaca actccaagta catctgctcc ttctcgcttg gctgctgcta cagcttcaag
    26281 aactgaacca cccgttgaaa taaggtcttc aaccactacc attttttgac cttgagctac
    26341 gcgaccttcg atttgattac cagctccgtg gtcttttggt ttgctacgga tgtaggcaaa
    26401 aggcaagtcc atcttatcag caataatggc tccgtgtgga atccctgctg ttgcagttcc
    26461 tgcaatcact tctacttcag gaaaggcttc tttgatagct tccacaaaac cattttcaat
    26521 tagggtacga gtttctggat aggctagtgt cacacgatta tcagtgtaaa tcggtgactt
    26581 gataccagac gcccaagtga agggttcctc tggtttgagg taaacggctt ggattttcaa
    26641 gaggtggcta gcgatatctt tagcaagtgt catggtattc tccttttatt tttctaatct
    26701 agttctttaa ttccagtcct gtgtccattc atccttgatg gcatgataag ctgcaacagg
    26761 atcctcagct tgggtaatgg gacgtcccac tacgatatag tcactaccaa tttgataagc
    26821 atctgctggc gtcatgacgc gtttttggtc tccaacagca gctccctgtg ggcgaatccc
    26881 tggtgtcaga cagataaaat ctggattggt ggcctgcttg ataagttgaa cttcctgtgc
    26941 cgagcaaacg acaccatcca agcctgcttc agctgtcttc ttggcatagt ggatcacaga
    27001 ctcttgtagg cttgtttgga tattttgaaa ctcctgcatc tgggcttctg atgttgatgt
    27061 cagctgcgtt acagcgatca attttgcttg acttccaaga ccttcacgcg cagccttcat
    27121 catctctaca ccaccagccg catgaacatt ggtcatatcg acaccaagct gagacaagac
    27181 cttcatggct gacttgactg tattaggaat gtcatgaagt ttgagatcca aaaagacact
    27241 atgacccaaa ccttttaagt aggacacaat ctcaggcccc gctgcgtaat aaagctccat
    27301 ccctaccttg agataaaggc tttcttctgc tgggaaaaga gctaaaaatt ccttgaccgc
    27361 ctcaaaacta ggaaaatcaa gagcaatgat tggacgatgt tctcgcatag gtttctcctt
    27421 ttacctttac tagtgagaga gtctggccaa cagaagccac gaaaaaagga acctgccaac
    27481 agcaaggttc cacgaaaaat gggtagtctc caccctttca ccgtctaacc ttagctgcct
    27541 ctctggactg ctttaaaggt tttctattat tctattattt ctactagcac ttgtcaagta
    27601 aaaacatggt cacgtatgtg ttgactgcta ttgaacacct cacaagactc tttccaaaag
    27661 aatagttaaa gactttcact gaggacagag aaaaagagtt tgcttgttac cctttaattg
    27721 aacaaatggg aattctgttt tattttgcgg atgcctattc atcttggcaa aggggaagta
    27781 atgagaatgc gaatggactt cttcgtgagt attttcttaa accgatttgg caacaattac
    27841 cgaaaaaatc cttaatggtg ctttgctagc ttattaatca ccgttcccaa aaatacttgg
    27901 attacaagac aggttttgaa gcacttatag aggagattta aaaatgttgc attttttatt
    27961 gcaatttatc agttatctta tcacccaaaa cttctgcaat tagtatgagc actattgtta
    28021 tttttctttt ttcgtacact caaatcaaaa tatagcaata agactattct gtagaattgc
    28081 tgtcaaaaag atcagttcat ttttccttcc cacttgtgtt tataatcatt aaaataactc
    28141 aattaagaaa ttttcttttt cctaatagtt atcgtaatta aagttaatag aagaacaatc
    28201 caaataagta gtgttagatt aggaattaga gtttcattcc atgaaaatcc ctcccatttt
    28261 gtgaaaaact tagtaaacag tcccataaaa ctataatctg ttatcttcgc aactgtctta
    28321 tccaaaccag atagcatcgg taagaaagca actaaaatca tagcaggaag actgataacc
    28381 tgagctacta cttggctctt cgcggttaaa cctatcaata aatagaataa aatgatggat
    28441 aaagaggtta gaagaacgat tgtaatataa ttaaaagtat gtacaattgt aactcctaaa
    28501 ataagaggag tagttcccat aatcacaaaa gttagcaaaa aaggaagaaa catcgttgat
    28561 aaaatgtatt cggatccttt aacaccactc aacagaagag tttgtaaatt gtacttttct
    28621 ttttcttcag acaagataat agttatagga cttccaacag ccaaagccaa agaaaaaggt
    28681 aaacacatca tcaaaagaac taattcctgt tgatcgttga ccttcccctg tgtttccata
    28741 agatatttac aaaaatatgt gaaagcaaaa ggcactaaaa cttgcaataa aatactctta
    28801 ttggaaagga taatttgaca acgcaaccat accaaagcca gaaaccgttt aagcatttag
    28861 ctttcctcct gttaatgtga taaaaatatc ttctaaagta ggctcacatg aatgaattga
    28921 aaaaatattt tccagatcag cctgagatac ctgttctagt gatgtaaaat caaaagttat
    28981 ctgattccca ttataatctg taaccttaat ctttttatct ttattatatc tttgaatgag
    29041 ttcagaagga gctccttgct caactaattt ccctttattt aataaggcaa cataatcaca
    29101 taaaagactt gcttcattca tatcatgagt cgttagaaaa atcgttgtcc ctgctgtttt
    29161 caattctaaa attaactcat gaattgttcg agaagttgtg ggatctagac ctgaggtcgg
    29221 ttcatccaga aagagtacag cgggtttgtt gataagagct cgtgctaaaa gcattcgttg
    29281 cctcattcca gtggataatt ttcctgctac catcttgcga ctatcatata atcctactcg
    29341 ctttaacaaa ttatcaacac gtgatttact aatattataa aatttactat aaaaaagaag
    29401 attgttatac agagacattt tctcataaaa tccacttgta tcgctaacca atccaattct
    29461 ctttaattca ccgcttgtta aattttgaga tttttgtccc aaaataatag attgtccttt
    29521 atcggcaagg aactgcccag tcagaatatt aatcgttgtg gtttttccag aaccagatgg
    29581 tcctaaaaat ccaaaaatct gaccttcttt aacagtgaag cttatattat ttaaagctat
    29641 tttatcacca aaactttttg ataaatggct aacttcaatc atactcattg cacctccttt
    29701 atattctaca tttttactta acatctattt acttagcttt atcaaataaa cgtcttaaaa
    29761 aaaacaataa cattaagcat ataaccgtta gcaagattgt ttcaatatta ttgataatat
    29821 gatacattct caagcagtat aaaataatta tatatatgca aatgctcatt atacctattt
    29881 ttttaaacat actaagcctc cttgccaaat aataaagtta tataataact aagacacact
    29941 atacctaaca taataaatat ccacagcatt aaaaatatta tcatacaaat aaaaatatcc
    30001 actggtaact gaataaatgt tctaaaatta acaagcaaaa ataaaatctc aaacgatgaa
    30061 aaaagccata ctatattttc caatgatgtt tgaatatttt tattgtagta agcataatat
    30121 atagcaaaaa taatacccaa gaacaatact attaattgtg tttctataac agtgaactgc
    30181 ccaatagcag ataaaaagct actcctcctg ataataagca aaaacaaact gaacgaataa
    30241 atgttttcgc tctaatattg ttatctttca ctttattatt ttttttacaa attggacatt
    30301 ctccgttttc cagaacatat ttttcttgac ttagagcatg atttctcata ttataaacgt
    30361 aagcgttatc tattagggtt tcattataac atcccagaaa tattttaatt attaaattag
    30421 tcattatccc tcccaaaata gcaggcatct ctggtgtagt cggccacttt gtcttatcag
    30481 ataaagtgta cttatttata tctttgttta tattccgaca accaaagcaa gaaccgatgg
    30541 tagggatata tatattatca ataataagat agcatccatt aaaccctcct gatatgtagg
    30601 atatcttatg cgatacagca aattgattga caatttttat aatatcaatg ggcgtatcaa
    30661 ttgctttaac gataaaatct atactcccat attccgcaac aattttttct aattcttcta
    30721 atgaagaaac tttaatagaa ataggtacta cctgaacatc tgaattatac ttgtgtattt
    30781 tttcagaaag aacattaatc ttctccttac caacatccga ctctgtataa agaatttgcc
    30841 tatttaaatt tgatggttct attatatcgt aatcagcgac aataagtttc ctcactccat
    30901 acatacttag acttaaagat atataacatc ctaaggctcc tgctcctaat actaatactg
    30961 ttttattctg tattttatta tactcttcat tataaaataa cgaatagtaa cctttagttc
    31021 tagaatatct actatcaata tctatctcat ccgaaattaa aatttgttca tttaatagtt
    31081 caaatgttag tttactgcct aatacttctt ctatctctaa tagttccttg atcgttgata
    31141 aattcttgcg aaatttgagg ttctatagct atttcccgca tactccgacc acgtaaatac
    31201 attatacctt cttttttata agcaaaaaca taactattta cgtagaacat atttcgtcct
    31261 tcctatcata tataatatag aaagcagtat agaaacaacc acccctccta tactacgaac
    31321 aataatattg ggtgtcaaaa actgtaatag ttgactcaaa gggaaataaa taataacaaa
    31381 tgctattaaa agttgaacta tatattgaaa attcaagtta ttattgttag aattcaagta
    31441 tcttaaaata ataccactat catactgaaa aaaaggaatt gaattaataa aaatcatacc
    31501 taagttaatg ataaaaaata agagtccaag caatttatac gatgtgaaca ataaaacaag
    31561 taaacctgta agtgataaaa tcgaatttga agcaattcct gctaacataa ttttcaaaaa
    31621 ttgtttttta ttttttagga attgcacccc acttaaatct acaaaaaaag ccaaattaaa
    31681 caaaagtagc attattccac aatttgggat ctcaatttga taattattag caattattgc
    31741 atgactaaat tcatgtatcg ttgcagatat aataacaaca agcaaccaaa ataaaagaat
    31801 gtttagcgtt attggaaagt tttggaaatt agtcaaaata tccgccctat aaatatacat
    31861 aataaaacat tgcaaaataa gagccaatgg gaaaatacca aataggattt tttcaaaatt
    31921 cttattaaat cttttatagt ttaatttttc agataatgtt atattaaagt cccaagatat
    31981 tttaaaaata tttatctttt ttcgtgattt catagaatct ataagtccca ttttactaag
    32041 aacaatataa aatcttaaat aatatttctt ccctactaac actaataagt ccgatatggt
    32101 aaattcttga cctattagtt gctctaacca tttttttcct gtttcccaac taatacatgt
    32161 ttcttactgg atggtatata tagatgatac tgtccctcat aaggagtagg taatatctta
    32221 atcttatcaa caattctcat aacaaaccta acctttaata aataaaagag gggctaagta
    32281 aaacatactc tagtccctca gtccgcaatc aataaaataa tgactaattc tattaatctc
    32341 ttgctgcaag actaatacgg aaaattcaaa tgactgtcta aaatgaaatt gaaaaagctt
    32401 gatgttagta aatgaacaaa cttcaacaac cagcaagagc aaggattgct aaaccaaatc
    32461 cgatacctgt tgcaagtcca gctgaaaaat cactaactgg tactgaaatt tcttcaattt
    32521 cctcaaataa aaagttatct tgcatgatta tcactcccta tctttttaac aacaggctac
    32581 tccaattaag agaactaccc cagttccaag taaaacttcc cccaaaaatt caccatctgt
    32641 aggggctacg atttcttcaa tttcttcaaa taagaatact tcatctgaca tatgtgttac
    32701 cttcttcatc aaaaattatt ttgtaatcga ttacattgca gatgtaacat aaagaaaaac
    32761 aaatgtcaaa tattaaacgt aaaaacatgg tcactaaaga actataagag aaaaggtaaa
    32821 cctagcgacg cgatgaacgc tgatttgttt gatttcgatt gctctcttcc tcttgttttt
    32881 tctgttcttc ttcttgtttt ttctcagctt ccttggcctc ttgtttggct ttttcctcag
    32941 cctccataat taatttatcc gccacagtgt aactgtaaat tccagcttcc atgtcgacca
    33001 cactcggttc tgacaattgt ggcttaatct tactgtaata tggcagtttc ttactcattt
    33061 cagatagagg aaccaagact tcgtccgaat cattcatggt caatcgaatt aaatcggatg
    33121 tcaccttgct tggggctaat tccacctttt ggatagccgc cttgagttct gggctaattt
    33181 gagcaagttc tgagacaaaa accttgattt gttcactatc attaaagaga actgataaat
    33241 aagtttctgg taaactgttc agactcacag aactagtctc aagctgacca ctggaaagaa
    33301 taggataatg attttcacca gaaatatagt aggccacaat atcatattcc ttgaccttaa
    33361 tagtgaactt agttggaaat tgatagacaa gttgagctga ttcaacccaa tagttagact
    33421 taatctgctt ttcatatttt gccttgtcta gcagaaggtt aatcgtataa tccgaatcct
    33481 gaatgcctga agcctgtcga atatcatcag ctgtagtttg caccgttccc tcaacacgaa
    33541 tatctttcat ggtcgcataa ggactgagca agtaggcaga gacaatcaat aaaagcagac
    33601 ttggaaataa aatcgtgaag gctcgcaaga tatggatacc aggaatcttt gctttggctg
    33661 gtttttcctt tgtagccttt ttagcaagct ttttatcctg ttcctccttc tctttagact
    33721 ctgattcttc tttctcttct ttctctttgt cagcctctga ggatgctact ttttcttcag
    33781 actcttcctt agctgattct gaatcttcct ggtctgtttc actctcctgg tcctgtttgt
    33841 cctctgactt ctcagattct tctcccatcc gagcttgtct ttccttttcc ttctcctcag
    33901 ctagagccgc ttcttcttca gccttctttt ttagatattc ttggtttcgt ttctgccatt
    33961 ctgataactc tttcaattct tcgaggattt ctttgtcctc atttttctta tcttttgaca
    34021 tttactttcc ttatgataaa tcttttttca acaattgata aaaatctgct agagatttca
    34081 attccttaga agctttcatc ttagcttggt aatcttcctt gtgacttagt aagtgagaaa
    34141 gcttctcttc caaactatcc aaggtcaaat cgctttcttg aaggtcttct gcatagcctt
    34201 tcttaacaaa gtaagctgca ttttcaatct ggtcaccacg actagcttca cgaccaagtg
    34261 gcacaatgac atgcaatttt gctatcgcca agagctcaaa aatcgtattg gcaccaccac
    34321 gtgtcacaac aatatcagcc aattccatca agggttgata gagatcggtc acatagtcaa
    34381 cacgaaaaag attttggctc aactcattca ggctagaatc tccagttaga ttgataatat
    34441 tgtagcgctc tgttagttct ttcttatggt ctgtcaccaa ttggttaaag acacgagcac
    34501 ctgcagaacc gccaacaaac aatacagtcg gcaatttatg attaaagtgg ctttgaatat
    34561 ccaccaattc atctggttct ggattttttt gatccgaaac cttggtcacc gctcccacat
    34621 gctcgacctt agccaaactc gaagcttgtt caaaggttga atacatctta gtcgcaaatt
    34681 tataggcgat tttattggcc aagcccatag acaggtcaga ttcgtgaata aagacaggca
    34741 ctcctgacac acgcgcagcg ataacaggcg gtactgagac aaagcctccc tttgaaaaaa
    34801 gggtctgtgg acgaagtcgc aacatgataa agagcgattg gacgattccc cagccaactt
    34861 tgaagacgtc cagcatattt tgccaagaga aatagcgacg caatttccca gtcgcaatag
    34921 aatggaaggt gacatccaaa cctgacttaa ggatttcttg gtgttcgata ccacgcttgt
    34981 ccccgatata gtggacttcc caaccatctt cgatgaactt gggcattaac aaaagattga
    35041 gggtaacgtg tccaaccgtc cccccacctg taaagacaat ttttttcata ttttattctt
    35101 ttaactccgc tactgtgtcg ataaagaggt cgccacgtac ttcaaagtta gcatacatat
    35161 cccagctggc attggcagga ctaagaagaa ccacatctcc ttgagtcgca agttcatagg
    35221 ccttacgggt cgcatctgca atatctgtcg cctccacata agcgacacca gccttgtctg
    35281 ctgcccgttt gacacgttct gcagattgac ccaggatgac catcttcttg agtccagtaa
    35341 tgtctggcac caattcgtca aactcattgc cacggtccaa accacctgca atcaagacga
    35401 ccttgctgtt gtcaaatcct gataaggctt tttgagtagc caagatatta gttgatttac
    35461 tgtcgttata gaatttaaca cccttgatgt catccacaaa ctggagacgg tgtttgacac
    35521 caccgaaggc tgaaagagtt tccttgatgg tttgattgtc cacatcacga agcttggcta
    35581 cagcaatagt cgcaagggca ttttccacat tgtggctacc tggaacaccg atttcattcg
    35641 ctgccatgac tacttcacca cggaagtaga gttgaccatc ttccagataa gctccatcaa
    35701 ccttttcaag tgttgaaaat ggtacaacag tggcttctgt cttggaagcc aagtcttttg
    35761 ccaagtcttg attaaagttc aagacaagga aatcagctgc tgtcatcttg ttctggatat
    35821 tccacttggc tgctacatat tcctcaaata atccatgata atcgatatga gttggcataa
    35881 ggttagtaat aaccgcaatc tcaggatgga attcttgaac acccatgagt tggaaagaag
    35941 aaagttccat aacaagcgtg ttcttgtctg tcgctatttg agcaacctga ctagctggat
    36001 agccgatatt ccctgataaa agaccatgtt gcccagcagc agtcaaaact tccccaatca
    36061 tagtcgttgt ggttgtctta ccgttcgatc ctgtgatacc aataatcggt gcttctgaaa
    36121 tcaaataagc caattccacc tcagtcaaga ctggaattcc cttggccaaa gccttttcaa
    36181 tcatgggatt gttgtagggg atacctggat ttttcaccat aagagcaaac tcttcatcca
    36241 agagttccaa aggatggcca cctgtaatga ccttgatccc ttcttccagc aaactttggg
    36301 cagctggatt gtcctcgaaa ggcttcccat catttactgt cacaatggca cctagcttgt
    36361 ccaacaaacg agctgcagat tcaccagact tggccaaacc taaaacaagg actttcttat
    36421 ttttaaattg atctattact ttcatgtctc gaactccatt tctactccta ctattttacc
    36481 atttttatgg aaataaaaaa gccacaaagt gtgtttgtga ctctttcttc tagctgaatc
    36541 ttgccatatc atctatgtga taaatcggta actcgaataa cttggtccac ttgttcccaa
    36601 ataagaggat tgtgggtcgc aataataata gttcgattcg gattttttaa agattctagg
    36661 atggaaagta attcctcaga gtttttgggg tctaaggaag cggttggttc atctgcgagg
    36721 atcaaaggtg gatcctttaa aattatcttc gctaatgcaa cacgttgtgc ttctcctcct
    36781 gataactcaa atataggttg cttcaaatcc aaataagaga ggtttacacg gtttagagct
    36841 tgtttcatca aagagatttt ctctttttcc ttcaactttt taccaactaa acccagattg
    36901 agattctctt tgacggtttg gctttcaatt aagccaaaat cttgaaataa gtatcctaag
    36961 taatctctaa agaaaacaga aggcttgatg tccttaagag aagtgccatc atagatgatt
    37021 tgccctttgt catatggctc taatcgtcca atcatattca agagtgttgt cttaccacag
    37081 ccacttgtac cgattaaggc ataaattttc ccaccttcaa aatgaagatt cgtatctgaa
    37141 aatagctgac ggcttccaaa ttttttagat atattcttta gttcaatcat cctattttcc
    37201 tttcataatt gtcatagaaa cacgagattc tttctgcgct tgacggtaaa gcgtcagaac
    37261 tgcactagct agaaagacta ataaagtgag caagccaatc accaagtctc gactgcttaa
    37321 aataaaaaga ctagcaccaa atacaaaact ggcaaattga ctaaccatat actgagcatg
    37381 tgtttcaaaa aatcgtaaac ctgaaattcg tttaatcaag atatctcggc ggaattgctc
    37441 gaaatataga agattgacag aataaaatag taacaaggaa ctagctatcc ccacaatagc
    37501 tcctaagatt aaagttgctg tttcagtttg aacttcatta taacgagtta gataaacact
    37561 tcttccttct ttaagatagg atacttgctc ataaattcca gctttcttca aaagttctag
    37621 cccactctca tatcctttga taaagagttg ttttccagca ttgatagacc aactagatag
    37681 ggatataaaa ctatcacctg tagaagtcgg cgtgaatacc actaaaatcg gatcagtcaa
    37741 atactgagtg gatacgggat tctcaccgtt attataaaca aaccgctttt ctcccattga
    37801 aagataacta acgtgcgctt tcatctcata atccaaagga gcacttgcct cctcaccaga
    37861 ttttccataa taactcaatc tttcttcaaa aactttctta agttctgctt ctcgagagcg
    37921 caaatgttct gggagcaaga ggataaactc acctttttgg agatgggcta acttctgttt
    37981 ggtctcagca tctaccacga ccttttcctt gtccaaataa ctgggactaa catagagcgt
    38041 attagcatct ggactatagg tatccagtgt ctctccctgt tcattttttc cttgtggatt
    38101 ggcaaaatgg agcagattat cctttacata aagagcttgt tcttcttcga ttgcttcctt
    38161 ggcaaaggca taccacttgc tctgattttc tgtatctttt cctctatcac ctaagccaaa
    38221 agaaatttga taatagtctg ctctatcctg ccatgcttgt tttgaaattt caagttcttt
    38281 caatcgttgg taagacgtca aacctgtctt aacagcgtat cctactgtaa agacagcaac
    38341 caactgacac aatagggtta aaatcatcag gcgtttaagg ggtaatctcc ccttaataac
    38401 gggaactaat gctttgtaat tcaaactcat tagataaaga agcattagta aaattgaaat
    38461 cgccaataaa aacaacagat agaaactaat cccaaaacca taggtggcta acaagatagg
    38521 ataaaacaaa ccttgactaa aaagaacgac tcccccacct aggaaggaaa ggagggctga
    38581 tagaaggagc catttgatat cagtagataa agaatgcccc atgatggata agagagtctg
    38641 accagaaaag agttttatac ctgctgctct catttcctta atccgagtga taatcactaa
    38701 agcaaagaaa gataagccaa atattgctaa actaattaaa ataaggggat ttagtaatat
    38761 tcgaaaagca agaaaatagg gcggtatctt tcggtcagca cttgctttat aacccaaatc
    38821 tcctaattta tcggcaagct tttctttcgt caaggagcct gacaaaagga gataactatt
    38881 tagcggatca ctacgttcac gactttcttg gctagcttct tggaattctt ttggtaaagt
    38941 tccctgacca taagttgcat aagtaaagtg agtcgtccca tccttactcg gctctacaat
    39001 tcttctagct attaaactct gttctgagtt tgcaaaattc tccaattcct gttcaaatac
    39061 ctcacgcgtc ggttcctgag tatctttttt gacacgaagt aaagaaacgg aatcatagct
    39121 tgcatataaa tattgtggcg cacgtaagac aataatccaa gcaaggaaga agctgagaaa
    39181 aaaagttgat aataatatga atagtttctt catagtagac tccttgtaaa caaaattccc
    39241 cctgtaattt cttacaaggg gaacgattta aatcaatgaa cgattagtca taatcacagt
    39301 aaaatgctac ttgttctccc catttagtcc aaatccatgc ataggaggtt tttccagcag
    39361 gagcttctcc tttatcagaa tgaccatccc atctgctcac gatggatgaa taatgatatt
    39421 ttttaccatg atagtaattt gaaaaagcct aaccacctcc tgaaccttct ccatatgtcc
    39481 atactcctcc atctggatat tgtacagcag ctgatgcagc tcccaataat gtaaaatttg
    39541 aaataagagc tagagcaagt aatctatgtt ttttcgtttt cattttattt tttctttcaa
    39601 aaaaagcaca ccttgagcaa caatgcaaca aaataaatcc tcctctctct tttattgaaa
    39661 ccgctttctt atgtgataag aataactttt ttattatttg ttgtcaagga aaaaatcgaa
    39721 ttttttagat attttactat attacctctg tgaataatat tatatagtag ttttatttca
    39781 aaataatatg caaccagtac taaccaaata taaaatagat gccattaacg aattttattc
    39841 aagtttttcc cattcatact atacaagtaa aagagatggt gttaactaaa aagcaattca
    39901 aactattgta aaattcctag caaaaagaga gccgaaactc tcttttttat cttcttttac
    39961 tttttttgac tggcatgagt gtgatgtctc taacactaaa gtaagctagg atcaacatgg
    40021 ctattgctag gaatatttct gttggtaatt gaaaaatttt cagaaaagat agaaccaata
    40081 aaatcaagag tgccactaaa atacatacca tagcgacgat attgacagtc cctttaatgc
    40141 tttctggtgt cgcaaataca tagagtagga gcagtaaaat tcctaggact aaatagacca
    40201 tctttctctc tttctagctc ttattcagct gattttttct tcttgttagc tttctcacgc
    40261 tctgctttgt taaggatttg tttacgcaaa cggatagact caggcgttac ttccatgtac
    40321 tcatcgtcgt tcaagaactc aagagactct tcaagtgtca agatacgagg cgtcttgata
    40381 acagctgttt ggtccttagt agctgaacga acgttggtca tttgttttgc cttcgtgatg
    40441 ttaactgtca agtcattttc acgagagttt tcaccgatga tcattccttc ataaacctca
    40501 gtacctgggt tgacaaagat cgtaccacgt tcttcgatag acatgattga gtaagttgta
    40561 gccttaccag catcgataga aacaagggca ccacggtgac gtccaccaat ttcccctgga
    40621 atcaatggca agtattggtc gaaggtatgg ttcatgatac cgtaaccacg agtcattgat
    40681 aagaactcag ttgagtatcc aatcaaacca cgcgctggaa caaggaagac caaacgagtt
    40741 tgaccattac cagttgaaat catatccaac atttcacctt tacgttcaga aaggctttgg
    40801 ataacagacc cttggtattc ttctggagtg tcgatttgta cacgttcaaa tggttcacat
    40861 ttaacaccgt cgatttcttt tacgataact tctggacgag atacttgaag ttcatagccc
    40921 tcacgacgca ttgtttcgat aaggattgac aagtgcaatt ctccacgtcc tgaaacagtc
    40981 catttatctg gtgaatcagt tgggtcaaca cgaagggaaa cgtctgtttg caattctgcc
    41041 tgcaagcgtt cttccacctt acgagaagtt acccatttac cttctttacc agcaaatggt
    41101 gagttgttga ccaagaaagt catttgaaga gttggctcat cgatgtgtag gattggaaga
    41161 gcttctactg catctgtcgg agtgatggtt tcaccgacaa agatgtcttc catacctgaa
    41221 acggcaatca agtcacccgc tttggcttct tggatttcac gacgttccaa accaaagaaa
    41281 ccgaagagtt ttgtaacacg gaagttttta gttgtaccgt caagtttaga aagggtaact
    41341 tggtccccaa ccttaactgt accacggaag acacgaccga taccgatacg tccaacgaag
    41401 tcattgtagt ccaaaagtga cacttggaac tgcaaaggct catctgagtt atctactgga
    41461 gctgggatat ggtcgataat cgtgtcaaag attggtgcca tagtcgcttc ttggtcagct
    41521 ggatcatctg acaatgaaga agttccgttg atcgctgaag cataaaccac tgggaaatca
    41581 agctggtcgt catctgcacc aagctcgatg aaaagttcca agacttcatc cactacttct
    41641 gctggacgag ctgatggctt atcgattttg ttaacaacca cgattgggac aaggtcttgt
    41701 tccaaggctt ttttcaatac gaaacgagtt tgtggcatgg ttccttcata ggcatctacg
    41761 accaagacaa caccgtcaac cattttcatg atacgctcaa cttctccacc aaagtccgcg
    41821 tgtcctggtg tgtccataat gttgatacga gttccgttgt aagcaacggc agtattttta
    41881 gcaaggatgg taatcccacg ctctttttcg atatcgtttg agtccatagc acgctctgcc
    41941 aattcagtac gtgcatcaag cgtttctgat tgtttcaata attcgtcaac cagggttgtt
    42001 ttaccgtggt caacgtgggc gataatcgca atgttacgga tatcttctct taattttgtc
    42061 atgatttcct ctataatatt caaaatttat tttctaactg aacgattata ccataatttc
    42121 aaataaataa cataactcaa gcaagtgtaa atgttttcac tccgcttttc ttttcacgtc
    42181 aagccttttc aaagcaagcg acttatgata agataggcac agtatgcgtt tagataattt
    42241 attagcccaa gaaaaagtta gccgaaaggc catgaagcaa gcactcctca gaggggaaat
    42301 tctagtcgat ggttgcccag cccgctccct agctcaaaat atcgatacag gactacaaga
    42361 actccttttt caggatcgaa tcattcaagg ctatgaacac acctatctta tgcttcataa
    42421 acctgctggt gtcgttacag ccaacaaaga caaggaactt ccgaccgtca tggacttgct
    42481 tccatctgac atccagtctg acaagctcta tgccgtcggc cgactggacc gagatacaac
    42541 aggactcctt ctcttgaccg ataacggtcc cttgggcttc caactcctcc atccccaata
    42601 tcatgtcgat aagacttatc aagttgaggt taatggactt ctaacacctg accatatcca
    42661 agcctttcaa aagggaattg tctttttaga tggtactgtc tgtaaacccg caaaactaga
    42721 gattctatct gcaagtccct ccctcagtca agcctctatc accatttcag aaggaaaatt
    42781 tcatcaaatc aagaaaatgt tcctctcggt tggtgttaag gtgactagcc tcaaaagaat
    42841 ccaatttggg gacttcacat tgaacccaga tttagcagaa ggtaactacc gccctttgaa
    42901 ccaaaaagag ttacaaatca ttaaaaacta tttagagatg agtcgataaa acaaaaaaag
    42961 ctttaaaact aaagcttttt tcttttattt accgaaaaat taaggcgatt gctacaatcc
    43021 agttaactac agaaatcaca attcctaaga tattaagaat cttttctatt ttatactcta
    43081 attgtgactc tttttggtat gaaatagcca agaccaatcc tatgataccc aaaatcaggc
    43141 ctacaattgg aaataacaaa ccaagaataa tcgacaagat acccacaaaa agtggatttt
    43201 tcttcttttc tttcatgttc taagaactct ttaaatttta tacaaattaa ttatactata
    43261 aaacaatagc ttcatcctat cattcgacta atttggaaat aaggttagct agtcttcact
    43321 ttccctttcc aagaatccaa gccataagaa aggatataaa tctcagaaaa accttgtttt
    43381 ttcaagtaaa gagctgcatt tgtaactcgt tgcgcacgtt ggttctcgta gagaaggaca
    43441 ggtttatctt tacgaagggc tgcaagacta gttttcaact gacttgaagg aatattgcgt
    43501 gcacgaagga tatgttttct gtggaattct gctgggtcgc gcaaatcaat caattgaccc
    43561 gtacgaatca aggcttcaaa ctcctcattg tccacaattt tagccgcacg gcgaatacga
    43621 agatagttaa agcccatcca cgccaacatt gctagtataa gtgcccacaa aatccaagta
    43681 accattagtt cttttctcca tttttctcaa tataatccaa ttctaccttg tgctctctgc
    43741 gaagaactgc ttctgcctct agatagtcta atttatccat caaccctgca tcgtaaatcc
    43801 gagatagttc caacttcatc agttcaatat catataagcg ttttcccatg taaacaataa
    43861 taccaaatcg tttgaggaat tgctgcacat catagaatgt tttcataaga ctcattctag
    43921 caaaattttg tgtttttttc aagaagagac tcacacaatg ctccttattt tcctatcttc
    43981 tttggcgatt ctaaggcaag tgtggtacaa taaaaacatg agaattcaac aattacatta
    44041 tattatcaaa atcgtcgaaa ctggctctat gaatgaggca gccaagcaac tctttatcac
    44101 tcagcccagt ctctccaatg cagtgcgaga tttggaaaat gaaatgggca ttgaaatctt
    44161 tatccgcaat cccaagggta ttaccttgac ccgtgatggg atggagtttc tctcttatgc
    44221 ccgtcaggtt gtcgagcaaa ctcagcttct ggaggaacgc tataaaaatc ctgtcgccca
    44281 ccgcgaactc tttagcgttt cgtctcaaca ctatgccttt gtggtcaatg cctttgtctc
    44341 tttgctcaag aaaagcgata tggagaaata cgaactcttc cttcgtgaaa ctcggacttg
    44401 ggagattatc gacgacgtca agaacttccg cagtgaggtc ggggtcctct tcttaaacag
    44461 ttacaaccgt gatgttttaa ccaagatgct ggatgacaat cacctgctat cccaccatct
    44521 cttcacagcg caaccgcata tctttgtcag caagaccaac cctctggcaa agaaagacaa
    44581 ggtgaaactg tctgatttgg agaatttccc ttacctcagc tatgaccaag ggacgcacaa
    44641 ctccttctac ttttcagaag agattctttc tcaagaacac cacaagaaat ccattgtggt
    44701 cagtgaccgt gccaccctct ttaatctctt gattggtttg gatggttata ccattgcgac
    44761 agggattttg aacagcaacc taaacggaga caatatcgtt tctatcccac tggatattga
    44821 tgacccgatt gagctggtct atatccagca tgagaaaacc agcctatcta agatgggcga
    44881 acgctttatc gactatctac tagaagaagt tcagtttgat agttgagaaa tgataagaac
    44941 caatatgtag gctagcaaca acctgcacat tggttctttt tacttataat taaaagtttc
    45001 ccctgccaac ttatcagcta gcttgggaaa gagagtataa aacttatggg ctaggttcaa
    45061 caaaatcggg agattgagtt ctcgtttatt ttttcctata atcttgacaa tctttttagc
    45121 cactgcatct gcctctaaga ggaagcggtc aaccgattta agataagttc catctgggtc
    45181 agcttggtca aaaaatcctg ttcggattgg acctggattg actgttgtca catagactcc
    45241 atagggcata agttcgagtc gcagagcatt tgaaaaacca atagccgcaa acttggtcgc
    45301 tgagtaaaga ctagacttgc cagtagctat tagacctgcc atgctgacga tgttgatgat
    45361 atgccctttg ctgctttcct tcatacgagc cgcaaggtga cgagacagat tcatcagggc
    45421 aaaggtattg acctcaaaca tctggtgaat gtctttatca gcaatctggt caaatccctc
    45481 aaaaatcccg taaccagcgt tgttaatcaa gacatcaatc ttgccatagc ggagataaag
    45541 atcagttacc agagcttcta gggctgaatc gtcggtaata tcaatttcaa tcaattctgc
    45601 atgggaataa tttccgtaga gttgggctaa tttttcctta tttctaccaa gcaagatgag
    45661 ttggtcattg ggcaggagtt tgaccatttc ttgagctaga ccaccgctag ctccggtaat
    45721 gagaatagta ggcatactta tcctttctgt gactgctaga tttccacttc ttccaagtct
    45781 ttgaccacat ggacattttc aaaaattgtg gcagcgtctt tcttgagttt gctaatatct
    45841 tttgagagga aacgggcact gatatggttg agtaggaggc gtttggcacc tgcttctacc
    45901 gctacttgtg cagcttgcat attagttgag tgaccatggt tacgagcaat tttttcatca
    45961 cccttgccat aagtggactc atgaactagg acatctgcat tgacagccag acgcacacta
    46021 gcattggttt ttctagtgtc tcctaaaata gtgataatct tacctggacg tggcgctgag
    46081 atatagtcag ccgccttgat ttcagttccg tcttccaaaa caagatcctg gccgtttttg
    46141 attttaccaa aaagcgggcc gaacggaaca ccagcagcct tgagtttttc agcatccagc
    46201 gtcccttcta gatccttttg catgacacga tagccaacac agaaaatagt atggtccagc
    46261 tcctctgcat acacagtgaa tttatcggtc tcaaggattt ttcctagaga atcttggtca
    46321 aactcatgga aatgaatgcg gtagggcaga cgagaacctg acacacgaag gctggttaag
    46381 acaaatgact tgattccttg aggtccgtag atttccaaat ctgtctgctc ttcattggcc
    46441 tgaaaggcac ggctagaaag gaaacctggc aaaccaaaaa tgtggtctcc atgcagatgg
    46501 gtaataaaga ttttgctgat cttacgtggt cgaactgtgg tttccagaat gcgattttgc
    46561 gtaccttctc cacagtcaaa gagccaaact tcgttaatct catccaaaag tttcagggcg
    46621 agacttgaaa cgttgcgagc tttagagggc tgaccagccc ccgttcctaa aaattgaata
    46681 tccattcgat actttctaat taatcaatat ataacatggc tgtgcggttt tccgatcgga
    46741 aatagcgttt gccagaaaaa gcagcagctt cttgcaataa atcctcttgg ctgtagcctt
    46801 tgagacgttt tcgaccatca gccaatcttt ccaaatcagt caaagctgtg agactttcta
    46861 ggctgacaac ttcctcgtcc tcgacaggct tcatgtaaat cttaccagac tcttcaaaga
    46921 ctaattgatg ggggaaaatt tgcgcaattt caaagagcaa gtcatccgag attttctcct
    46981 cattttcaga gaaaatccga ccaaggccgt cactatcata acaaaaacca aaggatttac
    47041 cagacagatt aagccgaata aaaggcttat tttctagggt gaaacttggc tcagtattgt
    47101 aaagattcag ttcctgactg agttctgcaa aataatccgt cgcagcctga ggactctttt
    47161 tctgatagag ttctgcaaag taggcattaa caacacttgg cggaggtgta ataagtgtta
    47221 actgctcctg ctctgtttta ccagctagaa gctgaaccag atagaccttg tccagacttg
    47281 tataacctcc atactttaga gccaaagctt taatatcagt cataaaattc ttctaacctc
    47341 catttatttt tttcggaaat gtagcctgta atcacttcgc tgtcttcctg ataatcacgt
    47401 tcttccagaa ttgcaacact ctctaaatca tgaatcttgt aggactttga aaaaggcact
    47461 cgcagggtaa atgcttcaaa aatttcctta atcttatcta gcaataatgc ttgcaagttt
    47521 tcacgactgt cctcagactt ggcagaaatg agggtatatg gcgtttgggt aggcgtgaaa
    47581 tcctccacca aatccgcttt attataaagc gtcaagtgag gaatatcttc catgtccagg
    47641 tctttcatga tggagagaac cgttttttca tgctcctcgt ggtaaggatt gctagcatcg
    47701 ataacatgaa ccagaaggtc cacatgcttg ctttcttcca aggttgactt gaaactggac
    47761 accaactctg tcggcaaatc ttggataaag ccaacggtat ctgtcaaagt tacttggaga
    47821 ttgcctccca gatgaatact cttggttgtc gcatccagag tcgcaaagag ctcatctgct
    47881 tcatactggg tcttactggt caagatgttc atgatagttg atttcccagc attggtataa
    47941 ccaatcaaac caatcttaaa agtgctagac tccaaacgtt tttctctgac agtcgcacga
    48001 tttttctcaa ccaccttgag ctggcgctcg atatccgtga tttgattgcg aacgctacga
    48061 cggttcagct ccagctggct ttcaccagga ccacgggaac caattccccc tgcctgacgg
    48121 ctgagcataa tcccctgacc aaccaagcga ggcaaaaggt atttgagttg ggctaggtgg
    48181 acttggaact tcccttcatg gcttcgagcc cgcatggcaa agatatccaa aatcaactgc
    48241 atacggtcaa tgaccttaac accgagaact tcctctagat tgacattctg ccttggggtc
    48301 agacggttgt tgacgatgac agtagtgatt tcttctgcat ccaccataag cgcaatctct
    48361 tccaacttac cagagccgac gaaggtcttg gaatcatatt tttcacgttt ttgtctgtag
    48421 ctatctacaa cgactgcccc tgccgttttc gctaaactag ccaattcttc catggagagg
    48481 tcaaaactgt ccataccctg caattccaca ccaatcagca ggactcgctc ctcttttttc
    48541 tccgtttcaa tcatctaaaa actcctctat ctggcttaaa atgcggtctt gtacaccaga
    48601 ttctccaatc tgataaaagg tgacctgcat gcgattacgg aaccaggtca gctgacgctt
    48661 ggcaaaacga cgggtcgcct gtttaagact ctcactagct tcctcaaagg tctgctctcc
    48721 acggaaataa ggaaagagtt ccttatagcc aattccttta gcagcctgta cattagggga
    48781 atggtcaaac agccacttgg cctcatccaa aagcccagcc tcaaacatca aatccactcg
    48841 gtggttgata cgctcataaa gttgactacg ttcatcatcc aagcagataa tcagcggttc
    48901 atacaaggtc tcttgatttt ccaaatcctg accaaaatgg gcaatttcta aggcacgcat
    48961 agcacgacga cgattaaact ggggaatctc aaggcctgct tgctccacaa aatgggctaa
    49021 ttcctcatct gaatacggct ccaaactagc tcgataagct aaaatctcct catgaggagt
    49081 ctccccacct aggtggtaac cttctagcaa gctctggata taaagtccag tcccaccggc
    49141 gataatggct agcttgccac ggctgtgaat atcctcaata gtcatcttag cttctgaaac
    49201 aaaatcaaaa gccgagtaag actcggttat ctctctaaca tcgattaaat gatgaagaac
    49261 agctgcctgc tcttctggac tagccttagc tgtcccaata tcaagtcctc gatagacttg
    49321 ttggctatct ccactaacca cttcgccatt aaaacgcttt gcaacttcaa tagctagagc
    49381 cgtctttcca acagcagtcg gtccaacaat cacaattatt tttgttttca tcttttttcc
    49441 ttgaaaaatt cccatttttt cgttactatt attataacac aaaaaggtca gtcagaaaaa
    49501 tgtgacctct tgaggaggct ggctgattga gaatataaag gaggaagact catggctaaa
    49561 ggattcgcta aaggtcttgt aacaggtgtc gcaggaactg tcgctgccgt tgcaggtgca
    49621 gtatacgcat ttaaaaagaa agtaatcgaa ccagaagagc aaaaagcagc tttcatcgaa
    49681 gaaaaccgta aaaaagcagc tcgtcgccga gtatcacgtt aagaaacaaa agaagttggg
    49741 attattctca acttcttttt tctattcttt taaatagcta ggtcaaactt caactgtggc
    49801 ttaacagggt cataatccac caactcaaaa tcttctgctt tgatatcaaa gaaattagtc
    49861 ccatcaggaa catttaaaac caagcgtggt tggcagtttg acggctcccg acggagcaat
    49921 tcctgagctt gttcaaattg attatcatag atatggaggt tgttgatgaa gtagaagaac
    49981 ttcccaacct tccagccaaa atgtttggca atcatcatct gcaaagccac atactgcata
    50041 gcgttgatgt ggtgggccac cagcatatca ttcgagcgct gggtcaaggt cgcatccaga
    50101 tagatttctc catctatacg gcggacatca aacatggtct gaaaggcgca cgggagcagc
    50161 ccatctgttt cttcgaaagc ttggtaatcc cagagcgaaa taatattgcg gcggttccaa
    50221 ggattggttt ccaactgttt gagaagctta ttgataatgt cgtgtttctt aacaacggca
    50281 ccatagcgct caccaatggt tcccgtgtct ccaacttccc agtcattcca gtagtgaaca
    50341 ttgtacttgt cattaagcac ttctaagcta tttgactggt cttggtaaat ccagagaact
    50401 tctttgatgg cggatttgat tgcaatggga cgcaaggttg tgataggaaa ttctccttta
    50461 gataagtcgt actcggaaaa ggcaccagtt acatacttgg aattagcaac agtcccatcc
    50521 ttgtacttag gacgagcctg ctctgagaaa acaccttcct ttagaatgcg ttcaatattc
    50581 tctttaaaaa tcgtatctgc ttttgtcatt tcgtttcacc tcattcattg tcctaactag
    50641 tatagcataa aaaataaaag aggaacatta ctaactctag gttagcattt tcctctctca
    50701 ttatcttatt gcaatacaag tgatgctgct ccgataactc cagcgtcatt tcctagagtt
    50761 gcaagagcta atttagtaga tgtgcgtact tgtgggaaac tattttcatc gtaaactttt
    50821 tgaacacctt gtagaaggaa ttctcccgca gctgacacac caccaccgat gacgattgtt
    50881 gatgggttta ggattgaacc aatgttagca caagcgattc ccaagtaacg tgagaagtta
    50941 cggtaaacaa tcaaagcaag gtcgtctcct tcttttgcga gatcaaagac agtcttagca
    51001 gttacttctt ctccgttatc aatcaagcgt ttcaaggctg catcgccttc gtattcatcg
    51061 gcatagcgac gagtcaagtt gacaatccct gttgctgaag caactgtctc aaggcagcct
    51121 tttttaccac aagtacatga gattggttgg tcaaagtcaa cagtgatatg accaagttca
    51181 cctgctgcac cagcaacacc atgaagcaat ttgccttctg cgacaatacc accaccaaca
    51241 ccagtaccga gtgtcataaa gacaacgtct ggttggttat ctccagcacc catccagcgc
    51301 tcaccaagag ctgctacgtt ggcatcatta tcgatgaaaa atggaatgcc caaagctttt
    51361 tcaatctttt gtttgattgg ttgaagggtt ttccagttca agttgtaggc accgataaca
    51421 gtccctttgt cacggtcaac cacacctggt gatcccattc caatgccttg gaagtccgct
    51481 gctgccaatc caagcaagtc caaacgatgt tgaatagact caatcatatc atcaacgata
    51541 tgacttccct catccaaaat gttggtcttg attgaccatt ttccttggat ttctcctact
    51601 gttgttaaga ttgcaaattt gatagaagtt ccaccaaggt caatcccaat aatcttttga
    51661 ctcatcatat tctccttttt cattgtgtag taattgaaaa tgcttacagt actagtatat
    51721 caaaatccat tcacttatgc aaaggtttgc gtaaatgaat tataaggaat tttttcgcct
    51781 accagtatct gttaatcatc taaatgatca atggcatatt gagctgcatc atttgaaaat
    51841 ttatcaaaat cagaagttaa ttgtctatac atacgttttt ttgacatgtg gaataacgaa
    51901 ttataacttt ttgcctttcc taaagcagca gaatattcac tattgctatc attactagaa
    51961 gaaactgtac ttgcttgacc ttccttccaa actccgtcag cgccaacata ataacgtcca
    52021 ccatcaaccc attcattgac agccatttta ccatccgatt ttagatagta atttccttgc
    52081 catgtactgt aagcataaga accatctgat gtcaaataat accaagcttg ataggtggca
    52141 tcataaaccc attcaccttt agccatttta ccatctgatt tcaaatagta gtttccttgc
    52201 catgcattgc gagcatatga accatctgat ttcaagtaat accatgcttg gtaagaagaa
    52261 tcataaaccc actcaccttg tgccatttta ccgtttgatt taaggtaata agctccttgc
    52321 catgcatttt ttgcataaga accatctgat gtcaaataat accaagcttg ataagaagag
    52381 tcataaatcc attcactctg tgccatttta ccatcagctt tcaggtaata gcttccctgc
    52441 catgcatttt tcactagatt tccatttcca tcaaagtagt accaagcgcc gtcctgctta
    52501 acccaaccac ttgttgttgc tgaacttgtg ttgatttgaa tagccgttga ctgttttgct
    52561 ttaaaagcac ccttaggagc atttttcaat tcgcaagcca caccatcatg atcacggtct
    52621 aacttggcag aataaccagg ttctccctcg tgaatatccg aatagccatt cgcccaagct
    52681 tccttacagc tcgaaaaatg gatgttttct tccgccaaaa ctggttgtga aaacaaggct
    52741 aaaattggca acgtcaccag actcattttt aaaaatagac gtttattcat ttctttctcc
    52801 cataattatg atatcgattt caatattatt ttatcaaact tatttcagca attcaaggaa
    52861 acttctggtc ttttctacaa actcctttgg ttttgcctta ttcaagacat gagggccatc
    52921 aggaatgatc tgaaactgcg aatctgttaa cagtctatgg agagctttca tagaactaag
    52981 attcggttta tctttgctgc cacaaattag taaggttgga taggagcaag tccctgctat
    53041 atccgttaaa tcaagtgtct tcaattcctc agaaactccg accataagag tcttgtctgc
    53101 tccctgtttt tcaaatactc ttttgggaag tagtttaaaa atcagcaact gaagataaaa
    53161 taggatattc cctgctaatt taagcgggca tcctgacaga atcaaagctc gaagatttgg
    53221 taaatcgtaa ctggaaagtt ctagtgtcag ggcagcacct aaggacaatc caatcaaaac
    53281 aaaaggttct gtctcttgag ctaggtgctg ataaactcgc tctttagctt gttgatagtt
    53341 actaactcca gaaggaaata actcgatagc ctcagaagga taatctgtca gtagattccg
    53401 aacttctttc caagactctg ctgactgccc taacccatgc aaaaatatca atttcatcta
    53461 gttctcctca aggcttagtt catacaagcc tctcactgca ttacagccgt aaatagcttc
    53521 tgcttgggtt aaatctgcca aggtcaagac tttctcttct acctgtcctg tttctagcaa
    53581 atgctgacgg taaattcctg gcaagattcc aagtcggata ggcggtgtgt agagttttcc
    53641 agcgattttc agaaccaaat ttcctataga ggtttcaagc agttctcctg acttattgtg
    53701 gtaaatcttc tcttgttctc ctaggctcaa atgcggtcgg tgagtggttt taaagtaggt
    53761 aaaggattga ttcaaagcag cttcctgaag gcagacttgg gcctgacaaa agcttgtact
    53821 gagaggggtt aatacttgac gattgacttc tatctctcca gatttgctaa ggctgattcg
    53881 caagcggtaa tcttgattag cttcacaatc ctgacactct tcctcaatct tgtgtcccaa
    53941 gtcttctgca tcaaaaggaa aggcaaaata acgactagct tttctcagtc tttccagatg
    54001 ttgatcttca aacagcaggt tcttctggct gatttcccct gtcgtaatca gttggaagcg
    54061 agcttgttta cgataaagaa ctgctgcctt ttgatgaacc tctcggtatt cagattccca
    54121 tgtgctatcc caagtaatcc ctccgccaac tccataaatg gcttgacctt tgtgaagttg
    54181 aatggtacga atggccacat taaaaatccg tcgtccattt ggaagcaaga gaccaatcgt
    54241 tccacagtag actccacgcg gttgaggctc caagttcttg ataatctcca ttgtcgcaat
    54301 tttcggtgca cccgttatgg aaccacaagg aaagagtgag cggaagattt caacaaggtc
    54361 cacatcctct cgcaactgac tcttgatggt cgaagtcatc tgccaaacag ttgaatactg
    54421 ctctacctgg cacagacgct ccacgtgctc gctcccaact tcagaaatac ggttcatatc
    54481 attgcgcaag aggtccacaa tcatcatatt ttcagagcga tttttgggat cctgttccaa
    54541 ccaactggcc tgttcaagat cttcttggtc agttacccca cgctgagtcg tccccttcat
    54601 tggtcgtgtt gtcaactcgc gatcattttg ctcaaaaaag agctctgggc tcatggaaat
    54661 cactgccatc tcgtcatgtt ccacataggc attgtagccc gcctcctgct ctaccaccat
    54721 acgattgtag atggcaaaag gatttgcact taacttttgc ttgagttgga cggtgtagtt
    54781 gacctgatag gtgtctccct gcctcaagtg atggtgtatc tgggcaatgg ccttttcata
    54841 gtctgctgca gacgttactt cctgccaatt tgagggcaaa tcaatatcct cataagtcag
    54901 aggaataggg gaagtttcta cgctatcatg aacagtaaaa taaagcaggt actctcccag
    54961 taggggatcc ttgtgaactg ctaatttttc ctcaaaagca ggtgcagcct cgtagctgac
    55021 ataccccacc acataataac cttgctcttg gtagctttcc acttgtgcca gcaaatctgc
    55081 cacttcttct acatttctcg ttttcaactc tttaataggc tgggtaaagg tatatctctc
    55141 ccctaaagtc ctaaaatcaa tcactgtttt tctatgcata ccttaagtat agcataaaat
    55201 aagaaaaccc tcatccgcaa agcagatgag agatttcgat tatctaaaga tagaagtttt
    55261 aaagctatct gtttgttgaa gaagtttctt ataaacagct tcttttagtt ttactgtatt
    55321 agtcatagat actgttttgt gaccgtttgc ttcttgttta agagtttcag catctttttt
    55381 aacagcttct ttaaatagtg taagtaaatc atcgtatgat gaaacggaag aaccatttac
    55441 ttcgaatgtt gttaatcctt tcgttgcttt atctttaact tctttgaaat aagctttttt
    55501 aaattcttca atagtgttga atgtattatt agatattttc ttgataatat attcatcact
    55561 tagaactgac tcgccatctt ttgtagattg ttgtttatat ttattcgaag tatagcctag
    55621 gaatccgtta aggtatccgt agtaacccca taatctaaag gcgttatgtt tgaatgaaac
    55681 agctccagga gcacctttac tagtattacc tccgtagata ccggctgtca tttcaacccc
    55741 cacataaggt gattgatcgt attggctaac gacttcaggt ttataaacac ggtttccaat
    55801 ttgtctatta gtcattaact gttgatctat taaactatca attgatgtaa tatttaagtt
    55861 atctttttct tcagttgtta gatttcgaat ttcgtcccac tgatttaatt ggctggcatc
    55921 tcggaatttc ttatctattt tcttgaacca tgctccattt aactctttat tattttgatt
    55981 aataacagca tctgcctcta aatgatcgac aagcattaaa gcatcattgt aaccacgcat
    56041 atatttatcg atatcatcac gtgttgtaag agatttagga tctgtatcgt accattgatt
    56101 accatcatta ggttttttga atacggtatt cagacctaat gaaccatatt cgttaaatcc
    56161 acttcctggg actggtagtt gtaacatacc ttgagcaaat gcttcagcat cagtaccttc
    56221 acgacgtcca aaaccaccca aatagatttt acgatcgttt atatgtgttg tttcatgagt
    56281 atacacagaa ataccataat ccccaatcat atttagagca acataactta catcagaacg
    56341 aggatccatt ggattatcat aaagtgcagc atatgctcct gttccattat aaccataata
    56401 tttttctata ggtccaaaga attctctaag aggagtatat acattgtcag tattatatcg
    56461 accgtatttt tcaacccagc cacctggcgc attataacct tcccagatag gaatcacagt
    56521 atctcttagt agatattgtt taacattatc tggaactaga cgataccaaa aatcatagta
    56581 gtttctgtac ccatcagcag cataatcaac agatgcttta atgtcttcta atgatttttt
    56641 tcctaatttc tcagcactac caattgcaat tgcgttgtag ttagaggcaa taaacatgtg
    56701 tgatttagtt atattcaata atggtaaaat catttttctg tgctgagcta cgtttaagtt
    56761 agcatatgct ctatatttag catttttaat ttcttcgacc tcagatgcgc gttctgcgat
    56821 gtagacatgg tcttttgtag catcaataaa ccaatcattc atattatcta tatttgtgaa
    56881 taattgtcta ttataattta agaatacatc taaattacct gatttagtat atttagctaa
    56941 tacttcaccg aatgcgtcga atgtacgtga acctttaatg ttgttctctt tagagccgat
    57001 ttcaattaat ctgtctaata cgctaacttt ttcaccatag aagtctggtt tgaataacat
    57061 taattcttta atattaacat caccgaattt aacaccgtag taacggttta agtatgttaa
    57121 acctaataat agggcagctt tgtttttctc gactttatca cgaagcattt gacgagcagc
    57181 tggagaatca tttaactggt gttcttcatt ttgaactaat tttgtgatta ggtttgttaa
    57241 gttcttttta acggctgtga agctttcttc taaatataaa tctttgattg cattaactct
    57301 atagtcacct aatcgattta ggtgttgata cattgtttga gattgaagat ctactggttc
    57361 taaaatagat tttatgtcat taacaagagt agtgttatct ttttgcacga tattgggtgt
    57421 atatttaatt cctaggtcag ttatagtata ttcttttaca ttacttaaac cttcactgct
    57481 agaagataag ttaaagtaat cttttgtacc gtctgcatag tgaacaataa ttttattagc
    57541 ttcatctagg tttgtgataa actcattgtt gttcatcgct gtaacagaaa ggacttcttt
    57601 agtatttaga gggtgttctt tatttaattt attaccttgg tatacaatat aatctttatt
    57661 gtagaatggt attaattttt caaggttttt ataggcttga ttatattcag cgttgtaatc
    57721 ttgaatacta gaataagctt tttcttcatt aagttttgca agaggagata gctcactttc
    57781 taatttatca gcagtaatat tgaaagtagc aactttagca tcagcttgtt ctttagttaa
    57841 ttgttttatt ttttgcagat tggtaaaatt attagctcca ctgctagcgc cgttgactct
    57901 ataaatatca gataagaatt ggcgtgcatc tccgtcatta atttcgtttg aaccatatac
    57961 ttcttcacct ttaattactt tagcataggt aacaatatct tttataactc cccaaggcca
    58021 agttttagct acaacaccac caacaaaacg agtattttta acatctaaag ttcctttagc
    58081 aaccgaattg gtaacttttg acttagttcc atactgatag ctatttaaca tatatgtaac
    58141 caaaggaact agcatacttg cgcttgcgtt agcggcagta atgttagcat caacataagc
    58201 tttattaaca aatcccatgt agttcgaacc agcaattcct ccgactgtag aattattacc
    58261 aacagaattg atattaccta taaatgctac gttttctaga gcagcatttt ctttgatatt
    58321 gtttacaaat ccagcaacgt tatttctggc tgttatcgtt ccagttgctt tgatgttttc
    58381 tatacgtgtg gttccgttga tttcattcgc aattgtcgcg atattatctt gattagacac
    58441 attaatatca atattttcaa aatttatatt tttaacagtt ccagctttaa tcttgtcaaa
    58501 taatggatgt tccaattcag taatagcaaa ttgttttcct tcagaactta aaagttttcc
    58561 tgtgaattct ttagtgatat atgattttcc attaggaaca acatttctag cgctcattga
    58621 ttgtcccaga cgatattctt ttgaaggatc gttttgaata gcttccacta attctttgaa
    58681 attataatat acattatctt cgtggacttt aggtttttca atatagtgaa cgtattcttc
    58741 ttcaaattta ttatcagcag ttctagagac taaattgtct gcgattgctg taactttata
    58801 tacatgtgtt ccgttaaccg tagtttcttc tatattttta acagctagta atgtagtttt
    58861 ctgattattt gaagttattt ttaaataata attgctctta tcatcaggaa tagttgttat
    58921 cagtgattca ttagtttctt ttccattttc gtatttgatt aaatctgtac gtttaatatt
    58981 tttaagctca acttttttaa gatctaattg aatattttga ttttctagag tttcagtttc
    59041 ttcaccgtta cctctgtcgt aaatcatagt tgtagatagg gtgtattctt tgtagtactc
    59101 taggttctta aatgcagcgc ttatagtttc tgttgttacc ttgtcatctg taagaactac
    59161 agtattaata acttcttctc cttttttcaa ttcagctgtg attgatttga tttttgtttt
    59221 gttttgattt tctagagtat acttagcaac agcttcacgt tccaatattt tcttatcggt
    59281 actagtcaat gttaatattg gcttttcaga taattcaacc aatttttcaa tagttgcagt
    59341 taatttttca acagcttcgt taacttcact ttgtttagca tctgtattag ctgcaacttt
    59401 ttcagccttt gtaacttcag tttggaggtt ttgccaactt ctatcactgt aatgttcttt
    59461 tacctttgtt tttgcatctg caatcgtatt gtttaattca gttttatcaa cgtttagagc
    59521 gtcaatagcc gttttaagtt tatttgtctc gctatttacc tcaggctgtt ttacaggctc
    59581 tgaagcatag acaccttttg cagtttctaa aacaggtcca agagcattgt aacttgctgt
    59641 agaataatca gtaggagaaa ctgaactagc tttatcaatt tgattattta actcactttt
    59701 atcaactggt tctttagtac caataccctt tattttatct tctggtttcg gtgtttcctc
    59761 tacagccttc tcttcttcag gaacttctgg ttgcttttct ggctcaactg gtgccgttgg
    59821 tgcctgttcg tcttctcttg gcgcgactgg ttcacctgct tgttcaactt ttggttcctc
    59881 tgttggttct gtttgttttt ctacagcagg cgtttcaact tttggttgtt caatagattg
    59941 attaacagtc tcctcttttg gttctacagt ttcttcagcc ttggtatctg gagttgactc
    60001 ttcttgtttc ggtgtttcct ctacagcctt ctcttcttca ggagcttctg gttgattttc
    60061 tggctcgact ggtgcctgtt cgtcttttct tggcgcgact ggttcacctg cttgttcaac
    60121 ttttgattcc tcagctggtt tgtctgatgg ttgactttct ggcttaactg ctactttttc
    60181 ctctggtttt gactcaactt ctccacctac ttcttcaact ggagctggtt ctgctgaatc
    60241 ttctttcccc tcttctactt taggaagggt gtcgtcagta ggttttacct ccgattttgg
    60301 ttcttccttt ggactttctt ctgttttagg tgcttcttct tttggagctt cctctgtctc
    60361 tactacttgg ttttctgtcc tagcttgctc ctgatttgtt gttgattgag gagtctcaac
    60421 ttcgactaca gtcacctctc caggttttgc tgaggtttct tctaaaacag tgtccaagcc
    60481 aagcgttttg aggatgtcac ctgatagata accaacatag cgatagccct ccatttcaac
    60541 aacaccctct cgactagcca gtgctagggt cgcaactggg tctacagccc ctgcactagg
    60601 aagaactacc aatcccatag ttccaactag aaagacgcta gcaattttct ttctcttgta
    60661 gattaaaagc aagctcccaa cagtcagcaa accaaaagct gtcaaaacag atgcttctgt
    60721 ccctgtttga ggcaactgat ctttttgata caccaaacca tatacaactt cattcctgtc
    60781 aggctttcct gtctgaatta aatctttagc ttcttgtgaa ataatctctt tatttacata
    60841 atttacatag tgataggtgg ctgcgtccac tacagaagga gccatcaaaa ggcttccaag
    60901 aaatacagag cctacaactc ccttaatctt acgaattgaa aaacggtctt ttttaaacac
    60961 ttttatctcc tttattcatt ctcaaaactt cctaatagca tcttgcggat agtgcgcacg
    61021 cgcacctccg attaattttg gacgactagt cagtgccgtt acatgggcat gaccaatctc
    61081 tctcaaaata gggcgaatcg gaacctgaac atgcttgaca tgcatgccaa ttgcagtgtc
    61141 tccgatatcc aatccagcat gagccttgat aaattcaacc tcaactggat cctgcataaa
    61201 cttaaaggct gccaactgcc ccgaacctcc tgcatgaaga gtaggatgga cactgacaat
    61261 ttccagacca aactgctctg ccacctgacg ttcaacaacg agagcccgat tgacatgctc
    61321 acaaccttga actgctaaat ggatacctct actacctaga atacccaaga tagtctccac
    61381 tatcagctca ccaatctctt gactggattc tttcccaatc tgaccaccta gcacctcact
    61441 agaagataga cctaaaacaa aaagggcccc ctgtttcaaa ttggtctttt ctaaaacatc
    61501 ttccactacc tgacgtgttt ctctttgaat ctgtgtctcg ttcatctctg ttacctctgt
    61561 tgtcactctt ctatcatacc gttttttctt gtttttagca agatagacaa cctagaaagt
    61621 ttgcccaatt acgcataaaa ctcccagaat tgactgggag ttagctagtt tctattctat
    61681 ttatatatat ttcaactttc gttccttttt ggggtctaga atcaatcttc atctggtaat
    61741 tggctccaaa atgaagtttg agccgttgat cgacattttg aagaccaact cccccacgtt
    61801 tgagttgact ttgactacta tcaccagcat cttggaagcc aacgccatca tcctcaatac
    61861 ggatgaccaa tcccgaatcc tgtttctgga cagaaagttt aatatggccc tgaccttcct
    61921 tttccttaat gccatggtaa agagcatttt ctacaagggg ttgtaggacc agcttgggta
    61981 agactaaatt atcaaaggca acattttcat taatttcgta ttccagctta tctccatagc
    62041 gttgtttctg gataaagaga tactggcgga catgattgat ttcgtcagag agacaaatca
    62101 agtccttgcc ttgattgagc gccaagcgga aataggttgc caaggacttg gtcacctgca
    62161 ccactcgctg actatcatga aattcagcca tccagatgat ggtgtccaaa gtgttataga
    62221 ggaaatgtgg attaatctgg ctcgaaaggg cttgaagttg gtactgacgg gtcgtttctt
    62281 cctggctacg aatagctacc atcaactgat caatctgatc caacatggca ttaaattggc
    62341 gagttacttc tctcagttca taggcaccaa cttccttggc acgaagattt tgagcaccag
    62401 aagcaatttc caacatggtt tctctcaaat ccttcaaagg agcaatccag cgtttaagac
    62461 tgaaccacac taagcagaga cagacaagaa gagatgtgac actggcccca agcaaggtcc
    62521 acaagagctg actccgaacc tggtctaact tttccaatga tgacacgcca agtaccgtcc
    62581 aatcagttcc tgcaatcttc tcttgactga cgtaggattt gtgaccagga gtataaccct
    62641 gacctgtctc gatgtagggt ttcatagcct ccattttgct agacgaacta taaactgtgt
    62701 gttgaggatg gtagacaaat tcatggtttt cattgataat gaaggcaaag ccctgctgcc
    62761 ccaactggag ttgattgaga taggcttcca gagtttcata agaaatatcc aaacgaagca
    62821 caccaagatt ggctcccttt gcatcaacaa gttcttgagt gacagaaatg acccactgac
    62881 tatctgattt acgagctgga gtcaaaacag gcatagctcc ctgatgaata gccttttggt
    62941 accaatcctc agccatcata tcagaggaag ttttcatctg cacactgtca tctgtagaaa
    63001 tgacctgacc agatttggtc accagcacaa cagttttcaa gtccttatct gacttcaaga
    63061 tggtcaaaaa caaatctcgg attccctcga ccttgtcttg actgggattc tcagcatagg
    63121 ccagaacatc cgtctgctgg gtcaaaccag tcgaggtggt ttctagtttt ttgatataag
    63181 actgaataaa gtggctagtc tggctgatgg tcgtttggct gttgccctca atggtggcct
    63241 caatggctga agaacttgat tgatagtaga aagttccaac cagagctagg agaatgagaa
    63301 agaccagaaa gatggaaata accattctaa ctaaaagaga agaacgcttc atcggtcttc
    63361 tcccttctta aactgacgag gtgtcacacc tgcaatctgc ttaaaacgtt gggtaaaata
    63421 gttcatatct tcaaaaccaa ccttctctgc gatctcataa atcttcagat ctgtagttaa
    63481 aagcaagagc ttggcttgtt taacacgttc tctcaccaga taatcctgaa aaggcaagcc
    63541 caactctttc ttaatcaagg aactcagata ggtcggacta aaacctaagt cactggctaa
    63601 agactttaaa ctaaattggc tatcagccag atgagactgg attttctggg ccatgtttcc
    63661 ttcaaaccta ttagtcaata aatcttgtaa ctgctcttct ttctcttcct tgtctagttt
    63721 ttgtttgatt ttccccaaca tttcctcaat atcctgacga gaaaagggtt tgagcaggta
    63781 gtcgtccaca cctagtttga cagcagacaa ggcataatca aaatcatcgt aacctgttaa
    63841 aaagaccaaa tgaacctgag gataggtttc tcgtaccaga ctggccaact ggatgccatt
    63901 tagatgaggc atgttgatat cggttaaaat gatatctggc acctgctttt ggatcaattc
    63961 ccaagcctgc cttccatttt cagcctgacc gatgatttcc atatcgtagg ctgctacatt
    64021 gaccagttta gtcaaacctt gtcttaccag atattcatct tctacgatta agattgtgta
    64081 ggtcatgctc tgctccttta ccacttacta gtatcagtat agcaaaattc tcctctaact
    64141 gcttaggaaa gacctcttat actcaataaa aatcaaaaag taaactagga agatagccac
    64201 aggtttctca aagtatagct ttgaggttgt aaataaaact gacgaagtca gctcaaagta
    64261 tagctttgag gttgtagata aaactgacga agtcagtaac cctacatacg gtaaggcgac
    64321 gctgacgtgg tttgaagaga ttttcgaaga gtattaatca acataatcta gtaaataagc
    64381 gtagcctttt tcttccattt ggtctttggg aataaagcgg atagagaggc tattgataca
    64441 gtaacgtaag ccgcccttgt cctgtggacc atccgtaaag acatgcccaa ggtgagaatc
    64501 tcctactcgg ctccgcactt ccatacgcgt catattgtag gacttatctt ccttgtaggt
    64561 gacaacatct ggactgatgg gttgggtaaa actaggccag ccacaaccag actcaaattt
    64621 gtcttttgat gaaaagagag gttccccagt tgctatatcc acatagatac cggattcaaa
    64681 tttatcccag taacggtttg agaaagctcg ttctgtttga ttttcctggg taactgcata
    64741 ctcctcaggt gacagggtct ttttcaattc ctcatcactt ggttttggat atttgctggc
    64801 atcaatgaca ggataggccg cctgattaac attgatatgg cagtagccat ttggattttt
    64861 cttgagatag tcttgatggt aatcctcagc caccacaaaa ttcttcaagt tttccttttc
    64921 aactgctaga ggttgatcgt atttcttagc cacctcatca aagacttggt taatcacttc
    64981 caaatccttg tcatctgtgt aataaacacc agtacggtac tgggtcccca catcatttcc
    65041 ttgtttattt ttgctggttg gattgataat gcggaaatag tgaagcagga tttccttgag
    65101 agaaatttgc ttggcatcat aggtgacatg gacggtttct gcatgacctg tttggttaat
    65161 caattcgtac ttggttgttt ctcctctacc atttgcatag cctgaaacgg catccgtcac
    65221 cccgggaaca cgtgagaaat attcctccac tccccagaaa caacctccag ctagataaat
    65281 ttcgtgcaag tctgcgtctt tactaatttc tgtttttttc actgcttttc ctccttggct
    65341 aactgccgcc ttttcaattt gcgaggcatc tgtctgccct gcatttcgta tcaatagaac
    65401 atagaaaccg gttatggcta gaaaaaatac tcctagcaac aagaagattt ttaacttatc
    65461 attcataaga cgcctcctag gctaattcct tcaaagtttg caaaattgca tctttttcca
    65521 tgaatcctgg atgtgttttg accagcttgc cttctttgtc tataaaggct tgggttgggt
    65581 aagaacggac accataagtt tccaaaagtt tgcctgatgg gtcaactagg actgggagat
    65641 ttttataatc caatccctta taccaattct taaagtccgc ttcagattgc tctcccttat
    65701 gtcctggtga cactactgtc aagaccacat agtcatcacc agcttcttta gcaatctcat
    65761 ccgtatctgg aagactagcc agacagatgg aacaccaaga agcccagaat ttgagataga
    65821 ctttcttgcc cttgtaatca gataaacggt aggtcttgcc atctactccc atcaattcaa
    65881 aatcagccac ctctttccct ttagctgcgc ttgttttact agctgtctgc tccgtcttca
    65941 tttcatcttt cgtttggtgt tcactagtca cggacttgcc tgaacaagcc gtcaaacaaa
    66001 ggagcgaacc tgctccaaga acacatgttt gccatttttt catattgata ttcctttcca
    66061 ttttattcaa ataattgact taaaattgaa gcatttccaa acagaaccaa gaatcccatc
    66121 acaataatga gaaaaccacc cacttttttg aggattccga gatagggatg aagttttcgg
    66181 aaatgtttca aaacataact agaggtcaga gctagaagca agaatggtag cgccaagccc
    66241 agcgtataca ccaacatgag accagctccc tgccaagctc ctgaaccacc tgaagccgcc
    66301 aaggccaaaa cagaccccag aaccggcccc acgcaaggcg tccaagcaaa actaaaggtc
    66361 aagcccaata aaaatgcctg actatagccc ttaccatttt gcccctgtcc ttgcagttgt
    66421 agcctctttt ccttataaag ccccttaaag tgtagaatct ccatttggtg caaaccaaga
    66481 aggataataa ttgccccagt aagatattgg aaccaagaag cataaagcaa atcgcctaaa
    66541 aaaccagctc catagcccaa caaaataaat ataaaggaaa ttcctgctat aaaggccaga
    66601 gttcgtaata aactagtaac tgagattgaa aatttgccgc tagaagcctg agcaccatcc
    66661 ttatcatcta gtaacactcc tgtatagacc ggtaacaaag gtaagataca aggagaaaag
    66721 aaggatagaa tccctgccaa aaagacactt agaaaaaaga aaatatgacc cataaagttc
    66781 ctcctatcat tttattgata gatttattat actccttcca ttttcgaaaa aacagggaca
    66841 atgatagggg aaaataggaa tttaatcaga tgatttagaa atcttggaca aaaactatac
    66901 aaaaaactgt caaagcacaa aagcgcatag tatcaagatt ctataaagcc ttgatactat
    66961 gcgcttttgt aatggataaa tagttagtct tttttaaaga cctgatcttt caaactctgc
    67021 atactggcat tgatcaccgc gcctaggata acaattttag caatcaagat aaaccaaaac
    67081 atcataacaa caagaagaac ggaacctaaa attcggacat ccaccaaatg atggacatag
    67141 taattgagat aactagagaa cagagttagt acacctaaaa tcaccaagag aacaaaggca
    67201 ctgcctggta gggtatagct aattttcctg ttagatagat tgggaagaaa ataataaagc
    67261 atgaccaaga tagcaaagag gagggcgtaa atcagaggac ctgccaaccc ttgtaaagcc
    67321 tgatagataa tgccatcttt tgtccaataa tgagcaagta aagccaaaat catctgacca
    67381 aataagatca aaaacaaggc aaacgcaaag aggaactgca agccaaaact gactaggaga
    67441 cttagcatct gatgggaaat aagtccacga ctcttttcga cgccataagc cttgttaaaa
    67501 gctttttgca agaaatttat agattttgaa aaactccata acgccgataa aacagaaaaa
    67561 ctcaataaac ctgttgaagg ttgcgtcaag acttctctgg ctattttttc cacaccttca
    67621 tagaggcttg ggggcaggac gtctttcata aagcccagaa attctcccac aggaatctga
    67681 aaatagggga ggatattgac caccaccaaa agcaggggga aaatcgaaat caaccaatag
    67741 taggctactg cgacactggt caactcacta tctgatgctt gataataatg caaaaaagct
    67801 tttaataaag gcttgtctat cagctctttc caccactttt tcatgtcata ctccttcatt
    67861 tataatctta tactcaatga aaatcaaaga gcaaactaga aagctagccg caagctgctc
    67921 aaaacactgt tttgaggttg tagataagac tgacgaagtc agtcacatac atacggtaag
    67981 gcgacgctga cgtggtttga agagattttc gaagagtatt aactaatttc ttcttaccaa
    68041 ttccaccata tcatacggca gggtattggc agcttccttc aaggaatagt tctctaagtt
    68101 atttacattt tgtcgtaatt tcttggcata cttagttgta attaatcgtt tttcttcgta
    68161 ttcgaaaatc aacttgcgct ccagataata gcctctcagc atttcattga tattgttggg
    68221 tttgacacga ttgataaccc gttcgacaaa tgcaccactg ctgataatag ttgtttctcg
    68281 aagacgagac tcctgcataa aactaatcaa agagcgtctg tagactccct tcaggttttc
    68341 caaactttca ataatcatct ccgtattggc aagatagagc tctgcaattt ggtcataatc
    68401 aagagcacgg agacggcttt gctccttgtc cttccagcta cggaaggtct ttccaagagt
    68461 aaaaacttca tgaaggagaa aacgtaaaat cctcaaggaa acaagaaaat aataggtcag
    68521 tcttgaggca agtttacgat tgattccttg ttctatattt ttcagataac gttggtaaac
    68581 tcggtaagca cgattgctaa tgttcccctc ttcataggcc tgttccaaac catcactttc
    68641 aatactaaga atcaagagtt tcaaagcagc ccagtcttct tgatcatcct ggttttcttg
    68701 gcttaaaatg agattttcaa tacgtccatg ataattgtca atagccgcat agaggggaag
    68761 tttatttctg gtgtcttcca actctttttc caactctagc gttacttcat tcaaaatggc
    68821 gatatgcatg agataatcct tgctttcttc ctcttcatca gaaagatgag gcaagatcaa
    68881 gagacctgtt aaaaagctga caagcgtcac acctgcaaca aggaaaagca aaagaggata
    68941 ctcttgttct agattacttg gtatcaagag aatcgtagca atcgacaccg ttcccttaac
    69001 acctgaaaag gtcaagagaa acatgtcctt catatactta tttagctttt tcttgaggcg
    69061 tcgggttcta taggcataat agccatagat cataataaaa cgaatgacaa agaggacaaa
    69121 ggtaagggcg atgagagata gcaataaaag tagaggatta tagattggat tggtcaagat
    69181 aggttctgct atcatttcca actccatccc taaaatcaca aagacagaac cgttgagcat
    69241 aaaggtcact gtatgccaga ccgtctcggt caccgtatcc acttgggctt cgaggagcgt
    69301 gattttcttg aaacgacttg cctttaaaat tccagcaact acgacggcaa taatccctga
    69361 aacatgaact tcttctgcca gaaagaaggt cactagaggc aaacttaatt ctaataaaag
    69421 ttcactggca atatccgttg cgcgcacact tagcaagaag gtatggagga agcggttggt
    69481 catggctgtt aaaaatccaa ttaaaaaacc gcctaggatt gaaaagatga gcgaactgct
    69541 agcttgcccc agagaaaaag ctccagttgt ccaagctgtc aaagctacct gaaaagccac
    69601 caaaccagaa gcatcattca agagtccttc gcccttaaga atattggaca cgcgcttagg
    69661 aaagctaaaa cgctccgaaa gagaggcaaa ggccaccaag tccgtaggac caagggctgc
    69721 cccaacagcc aagcaagctg ccaagggaag gctgaaccaa agaagatggg ccaagccacc
    69781 caaactcagg gtcgagataa aaatcactgg aaatatgaga taaacaatga ttcgccagtg
    69841 ttttaaaata gccgtaacat ctgcttcttc agcctctcgg aaaagcaagg gtccgataac
    69901 cagggccaaa aacaactccg tattgaggtg aaagtcggta ttgggtaaaa agagaccaat
    69961 cacaattccc aaaagaattt gcaccaaagg gagaggcaaa aagggcagga gcttattggt
    70021 tgtacttgag acaatcaaaa ccagtaaaaa taggatgagg taaatcagta attccacgca
    70081 cgtcctcctt aatctttttt acaacaggat tcaaatatct ccttctgctc tttgattttt
    70141 tggtcaatct tggaacagtc tttgtgctca atttttctct ggcaccgttc catttcaaga
    70201 gcaactaatt ttttcttgat tttaagcatt tttttgctca tatgcgcttg gtctagcacg
    70261 cccaccgatc gttcgtggtg ggttgattca acaaaattct ggcgcatggc atccagcttt
    70321 tcgtgtaggt attgtttatc catgtctgta tctctctaat ttttcaatca tcactaaaaa
    70381 cggcgggttg ttgacttggt ttaaagttcg gtaaatggca gctgtgtact cttgttggtt
    70441 caactggatt acaaaatcca agacagcatc tctctcgagg tcgcctcctt catgaccata
    70501 gtaaatcata atagcaattc gtccaccctt gacaagtaag ccacatagct tttctaatgc
    70561 ctcaatcgtt gtctgcggtc gggtgatgac agacttatca gctgacggca aatagcccaa
    70621 attaaaaatc cctgccttag cttttgtcac aaactggtcc agtgtctcat ggccttgcaa
    70681 gattaactgg gcatttgtca agccagcctg atgcaaacgc tcttgggtct tttccaaggc
    70741 ttgcttctga atatcaaagg catagacttg cttggctagc ttggctaaaa aaagcgtgtc
    70801 atgaccattt cccatagtcg catccactac gacatcctct tttgtcacga cctcagccaa
    70861 aaaatcatgt gccatctcaa gtggtctttt cattttcaaa ctcctgtttt acagccttgc
    70921 atccttgaac acttccacga cgtcgcatct ccatctcaat gctgttgaga gcttcccatt
    70981 tattgaggct ccacataagc ccaatcagca tatccctagg tgcatctcct gtgattcgat
    71041 ggatgacgat atgtttggga atgatttcca gttggtcaca gatgaccctg acatattcgt
    71101 cctgactcat caattgtaaa cgtccctcat ggtaatctcg ttgcatacga gtatttgtca
    71161 taagatggag caaatgcagt ttaatccctt gaatatcgtt attcgtgaca caacggcgga
    71221 cattttcaac catcatctca tgggtttcac caggcaaacc attaatcaaa tgggaaacaa
    71281 tctcaatctt gggatacttt ctcaaacgct tgaccgtttc cacctacaat tcataagaat
    71341 acgcacggtt aatcaggtca gaagttgctt cataagtagt ctacaagccc aattcaaccg
    71401 tcacatgcat gcactccgat aactcagcca aatattcgat ggtttcgtct ggtaaacagt
    71461 ctgggcgcat tccaatattg attcctacca cacctggctc attgatagcc tgttcataac
    71521 gctctcgaat aacttccacc ttttcatggg tgttggtaaa attttgaaaa taaaccagat
    71581 acttctgaac atccggccac ttacggtgca taaagtcaat ttccttataa aattgctcac
    71641 ggataggcgc atctggggct acaatagtat ctccagaacc tgaaaccgta caaaaagtac
    71701 agcctccatg agccacagtt ccatcacgat tgggacagtc aaattccgca tcaataggga
    71761 ctttaaaagt cttttctcca aagagttttc gataataatc attcaaggta ttataagatt
    71821 ttataacttt cattataaca aaaatcaccc acaatctcaa aagcctgact ttcctataaa
    71881 ttcctctgtt tctcgtttcc attagctttt ttttatgata caatatgggt atgattttaa
    71941 tgaaattagc atctatttta ttattgatac tgaccttagt cgtctgcatt atcctaacca
    72001 aactttttag attaaaaaaa ctaggacgaa actttgcgga tttggctttt ccggtcttgg
    72061 tatttgaata ttacctgatt acagctaaaa cctttaccca taatttcctc cctagactgg
    72121 ggctagccct ctcaatccta gccattattc tcgtcttttt cttccttttg aaaaaactca
    72181 gcttttacta tcctaaattc atcaaattct tctggcgtgc aggattctta ttaaccctta
    72241 tcatgtatat agaaatgatt gttgaattgt tcttaatgaa atagtcgaat ccctaagcat
    72301 tttctaggga tttttgcttt ctctacaaaa tagtatagac aataacacta tacaatttta
    72361 tacaaagaaa agagtctggg acaatagtct cttatctcca aaaaaagcaa cggatttgcc
    72421 gttgcttttt ttgcatggtt acgatagtct tggtaaaata gaattgccca ataaaccatt
    72481 tagaaaggct atcccatgca tattcactat aacacaaatc aaacaacttt accactagaa
    72541 atcagttcct tcttaccaca agaccatctc gtctttacta ttgaaaaagt ggtgaatacc
    72601 ttggaggaac atcacttcta cgccttctat catgcctttg atcgcccgtc ttatcacctt
    72661 aaaatgcttg tatctactct tctatttgcc tattcacaag ggattttctc tggtcgaaaa
    72721 attgaaaaat ggaagagtta gtgaccttag attgtttgtt tattgacgga actaagattg
    72781 aagccaatgc caacaagtat agttttgtgt ggaagaaaac gacagagaaa ttctccgcca
    72841 aacttcaaga acagatacag gtctattttc aagaagaaat cctccccttc tgattaaata
    72901 tgccatgttt gataagaaac aaaagagagg acataaacag tcagctaaaa acttagcgaa
    72961 ttggcactat aatgacaagg aggatagcta cacacatcct gatggctggt attatcgttt
    73021 tcaccatacc aaacatcaga aaacacagac agactttcaa caggaaatca aggtttacta
    73081 cgctgatgaa cctgaatcag tccctcaaaa gggactgtat atgaacgaac gctatcaaaa
    73141 cttgaaagct aaagaatgtc aggcgctttt atctcctgaa ggtagacaga tttcgctcaa
    73201 cgcaagattg atgtgaaacc tgtctttggg cagataaagg cttgtttggg ttacaagaga
    73261 tgtaatctga gagggaagcg tcaagtgaga attgacatgg gattggtact tatggccaat
    73321 aacctcctaa aacatagtga aatgaaataa gaccaggaca aatcgataag gacagtcaaa
    73381 ttgatttcta acaatgtttt agaagtagaa gtgtactatt ctagtttcaa tctactatac
    73441 aataagagaa cgactcaaaa ttaaaaagct agagttccgc aattggaaat atctagcttt
    73501 tttgtggttg agaactattt tgttccagac tctttatctt ctatttagga caagagtttt
    73561 tctttggtct ttaatgataa agaaggtatc aaaatttcta gtcttctttt ttacctttag
    73621 taactactaa tcctgcactc aaacctagaa gagctaaacc tgctgctact gctgcttggc
    73681 ttgccgcact acctgtattt ggtaactggg ctttattagt ttgatcagct tcacttgaat
    73741 caattggttt tgtatctgct ttttctgaca cttgtggttt tttagcttct tgagctactg
    73801 gtttggttcc aaccaagacg atgcggtctg tcggaacttc taccacttca cggagttttt
    73861 cttccttact tccatcagga ttaatcactg taaagatacg ttcttttcca acttttcctt
    73921 cttgttctac acgagtttca cctagataca gtgttgaatc ttttttctca actgtcttgt
    73981 aggccaaatc tttttcaaca aattcgagtt ttggaagatc ttcttgtaca gcagaaactg
    74041 gtttttcctt agtcaactgg atacggtatt ccttgacttg ttttccactt tctgaaacga
    74101 ggcgaacaag tactggaagg ctatcttctc cactatctac cacagttgaa gctacttgat
    74161 tgttttcttc aactgagact tttggccgtt gacctttata ggtaatttga tagtcttgac
    74221 gattttcagc gaaatcagca agttcttttc catctacaag aatctttgat tgcgtgcttt
    74281 cttgaggcaa ttcacttggt gcaaggaagg tcatctcaat catcgcaaca ccgctcttgt
    74341 cagctttacg ctccatacgc catctcatgg ctttggcttt gacagcttta aatgttacgt
    74401 tgatttcatc accagctgcg atgtctttat ccgcacgata aggcacagct tcccaatttt
    74461 ctggattgtt aaatggatgt ccagattcgt aggcttggta gtttgaatag taggtaggta
    74521 cttcaaagcc tgggccgaca tagcgttcta aaacgagttt agatggtgca tccgtaccac
    74581 tatctgcaaa gaagtgaagt ttggcttgag caacagtccg ttctacaatc ttaccatttt
    74641 cacggaagat cacacccgct gatacttctg gattagaaga tggtgttggt gaccagtttg
    74701 tccaacgacg attttctgaa tgatctccgt cattgagata gtcaacgcgg tcatgagagt
    74761 ttttgtcaat atcattggtt gctgaagcaa aggcctggtt actgttttca tcatagttag
    74821 ggttatctga aagagtctca ccaagtttgt ctgtcactcg tacagtgacc tcagcaacaa
    74881 ggttactacc aaggacacgg cctcgaacag taaattgacc tgcttttgtc agattttccg
    74941 ctggaacttc ttcccattca actgtcaggt cttttgtttc gtagccgtct ttacctgtga
    75001 agtaaactgg aaccttagtc ggcaattcaa gtgcttgacc tacttgtagc aagcgagctt
    75061 gtttaaccgc agcaactggt ttatgagaaa gtaagttctt atccttagtg aagtgcagac
    75121 ggtattctcc taagatgtcg ccattttcag ctttcgcgat gacacgaact ggctcacctt
    75181 cacgaacgct tggaacgacg gtagcgagac cattgttgct aacatttgct gtgactgccg
    75241 gaacttttcc atctacagac tcaaggtagt agtctgtcaa atcagggttg aagtttgcta
    75301 agtctttgcc gtcaacttgg attcttgttt gtccttgttt ggctgccgca acttgtttcg
    75361 caaagatttg tacctctgtg atagacgttc cacgcttgtt atctgcttta accatgcgaa
    75421 tacgaatagc ataggtttca actttatcaa agctaaagtg gttcatttct ccagccttga
    75481 gttgagcagg ggcttttaga ttagtaactg gtttccagtt ggcagaatca ttaaagacat
    75541 ggtcctcatt accaacaaaa ctagggtttt taggagctgt tgggacagtc ttaccaacat
    75601 aatactcaat cacataagac ttcggtgcac caactccatg gtcttcgtgg aatccgacac
    75661 ttagattatc aacggagcgt ttgctcaaga tacctgaatc tccaaacaga acaccgactg
    75721 aagcttctgg attactacga ttccagtttg tccaacgatt ggctggttgg ttattgtagg
    75781 aaatgagctt gtcattaaca tttgaaactg ggtcgcttgg atttgaatct gaagcaaagg
    75841 caagtggcaa ttctgaaccg gtccattggt cagaaatgtt tgcaccttgc tcagtttgag
    75901 cagatacgcg aacatgaagt ttagttgtta attgagtacc ttctaagcga ccattaactg
    75961 taaagacacc ttccttagcg tattgctctg gacgaatcgc atcccatgca accttagctg
    76021 atgaaacgtg accatttgaa tcatatgtcc gaacactttc tggtaattgt ggtgcttctg
    76081 cgattggagt tgtcacactg acttcttcaa ctgaaacgat accttctaca gagacttttg
    76141 cacgcgcttc aaggtcaatt ccttcaactt tacctagtac ttcaaatgtt tgataggagt
    76201 ctagtttttc tttcggaata gcttgccaag tgactttatg agttttaggg aaacctttgt
    76261 catactcaac tgttactgtt gctggaagac ttggttcctg atgcaaatct gtcactacat
    76321 ttacaggacg gatggattgc gcaatcttct tctcagtatt ggcttggata gtgagttcaa
    76381 cttggccttt agctccctca tattcagcgt tcagagtgac tgctcctggc ttatgcaact
    76441 caagcattcc tttacgaatt gcgacttccc cttcaccact tgtagagaag gttactttat
    76501 cagctggtaa tacagcttgc gttccatctt gatagtgagc tcgaaccgac aatttgacag
    76561 tttggtcttc tttgagactg tcagcttttt ccacttgcaa gctcaagtga gcaatttttg
    76621 gcgcttcttc aaggaattga attgcatagg tttgaagagg gccaccatct ttaggctgaa
    76681 taaagatgct cgcacgcatg ccgtttgctg cgcttgcttg aagaactgta acagctgcat
    76741 ttttagcact tgctgtgact tctggcaact tagctccata agcaagagtg cggtattgca
    76801 ttggtttttg actagtaaga cctgtgacag cttcaccacc aaccgttaca gttggtactg
    76861 caggtgccgc aggattgcct tcttctacca caagggttgc atgaattggt tgaccttcta
    76921 aataaccggt cgcttgaata cgagaacctg gaattgctaa cttagcttta tcttcttcgg
    76981 caatctccca cttgtccact tcatactctt caacacttcc atcagtcaaa acataggaaa
    77041 cagatttgtc tacagaattc aagtcagtat ttggagcaat acgtttcaca actggtagct
    77101 ctgatttaag agcaatcact tctacacgag cttctacttc tcgtccgtca gccatacctt
    77161 tcaccgttac aataccaggc ttgctcacat ctactgaaga ccaggttaca ggacgttctg
    77221 cacggctacc atcactgtat acaaacggaa cagtggtagg catttcaggt gcctctccaa
    77281 taatggtctg tacttttggc acttctgtcc ccaaaacagt cttctcttgt ccttcttttt
    77341 taccagtaaa gacagtgact tgactagatt tcaagagatc tgaatgggct gtcagtgtga
    77401 atttccctgc ttgttcagtt gatttgacaa tggcaacacc tttaccatta aatgctttac
    77461 gaatccaaga accatctgct tgcgccttat agcgttcacg gctggcttgt tctccgttat
    77521 ctacaccgac cagttgacct tggccatgca attggaagcg aaccagatta ttagcagttg
    77581 gaaccacatt cccctggctg tcaacaattt catagtagat gtaagtcaag tcttttccat
    77641 ctgctgcaat cgcatggtct tccttaataa gacgaactgc cgctggctta ccagcagtcg
    77701 taatcttatc tcgagcaatt tccttgccag attcatcacg agcaattgct tccaaggtac
    77761 ctggttgata ggcaactttc cattcaagat aaagttcatt agcatttgca ccttcttggt
    77821 aagtccgccc atcgctggtt tgttttttat tgaaagtctt aagaccaaga gattttccat
    77881 tcaagaacaa ttctacacta gaagcattcg aataagcacg aactggaatc ttaccttctg
    77941 agtcagctac tttggatgct aattctttgt tttcccagtt ccagtgagga agaaggtgta
    78001 ccatcggttt cttcttaaca gaaacccatt ggctttggta gaggtagaag tcatgttttg
    78061 gaatgccggc tgtatctacg ataccaaagt aagagctctt aacaggagtt tgattttggt
    78121 tgtgccatgg tgtaggttca ccaatatagt ccgtacctgt ccagataaac tgtccagcat
    78181 agccagcgtt gtcacggtca aaagtccatg aagcggttgc tgttttcccc caaccaacac
    78241 gatcattccc atagtcagac tgttcataat tacgctcagg tccattgcta tgtttcaatt
    78301 cacgttcagg gcgatagtaa cttccacgtg tacgggtagc tgaagatgtt tctgatccat
    78361 aaatcaacca ttttggatgc ttagctctaa gggctttgta attatcttca gaatagttaa
    78421 atccaacagc atcgagttca tcagcaattt tctcatgccc tccgctacca ttaccgaaac
    78481 ggaatttatc tgctcccatg gtaacatagc gagtcttatc aacatccttg ataaccttga
    78541 ccaaacgttt aacagttgct aaagagtggg catcaccatt agcttcacct atttcattac
    78601 caattgacca catgaagata gcagggttat ttttgcctct ttcgaccatg gtacgtaggt
    78661 caaaatcaga ccatttttca ccttttcgag cttctgggtg agtggcatct ttttcaaaga
    78721 aacgtccata gtcataaggt ttcttgccac cataccaagt atcaaaggcc tcttcctgaa
    78781 cgagtaaacc tagttctgct gcgatttgca aggtttgctc actagcaggg ttgtgggttg
    78841 tacggatgga gttaactccc atctccttca tttgtttgag acggcgatat tctgctttat
    78901 agttttcttc tgctccaagc gccccatggt cgtggtgcaa ggatactcca tggaatttaa
    78961 tacgttcacc attcaaagag aaaccttcat ttggagtcca gtgatagtaa cggtaaccaa
    79021 acaaatcctt cttagcatca accaattgac cgtcacggta aacacgcgta atcaattcgt
    79081 acaaggcagg tttgtcattt aaaacggtcc agagttttgg tctttcaact tctaaaatcg
    79141 catctaggct tgttgattca tgtgctttta aggtacgact cgctgtacga actaagcctg
    79201 ttacagcatg accacctcgt tcaacgattt gatattcggc tacaagttca tggtctttgt
    79261 cgtccgtatt gacgattttg ctggtcacat gagtttcaac cttgccatgt tgttgttctt
    79321 caagttttgg tgttaaaata gttgtcccat ttttctcaac atgcacctta tctgtcactt
    79381 gtaaagtcac atcacgatag ataccacttc ctgaatacca acggctactt ggctgtttgt
    79441 tgactgcatg gacagcaatc acattctcac gaccatcttt atgaaggtat ttggtgatat
    79501 cgtatgagaa ctggttataa ccatttggat aatgccccac taactgacca ttgacataaa
    79561 cttgagaatc catgtagacg ccatcaaaag taaggcgaac atttttcttg aggtcttttt
    79621 catctagttt gaaagtcttg cgataccaag cttccccacc gttgagctgt ccaccttcat
    79681 tttgtgcagg agattcatga tcgaaatcgt taaagatact ccagtcatac ggtaaatcta
    79741 attttttcca cgtagatacg tctgcatcag gtttaatggc ttccttagaa tttgcattga
    79801 gtttaaagta ccaattttga ttaaaatcca ctttcctgtc ttcaatcatt tgattcactt
    79861 cttcatttgt tacagcttta gcatcttcct tgagcggttt ttcttgactt gaagcttgtg
    79921 attctatcct tggagctttt tcttccggtt tagcagacac tttttcctct tttggagtta
    79981 cggcttcatc ttctttcttc tcagatgcaa tagcctcagt tgaactaggt tcactttgtt
    80041 ctgtcctttc aactacattt ttagtttcca aagctttatc agccttttct tctactatca
    80101 ttttttcctc tttaggtttc tcagcagtat gagtaataag tgtttcatcc gcataaacta
    80161 cagattctcc agctatattt cctcctaata gaactgcaca agtcccaatc attactgagc
    80221 aagctcccac agcaaactta cgaatgctat aaactctttt ccgattccaa tggcctttcc
    80281 ccataaaacc ctccttatat tatatttagt gcagttagct actaccaaag cccaagtggt
    80341 atacatggta tgacaaccta gtttcaacaa tttacactct gcgaaaatcc aattcaaact
    80401 tcgtcagtgt cgccttgccg tagatatgat t
//
LOCUS       DBERAE010000004        69500 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.04, whole genome shotgun sequence.
ACCESSION   DBERAE010000004 DBERAE010000000
VERSION     DBERAE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 69500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.04"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(409..1269)
                     /locus_tag="ACL70N_000346"
     CDS             complement(409..1269)
                     /locus_tag="ACL70N_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGS0589227.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1285..2562)
                     /gene="spxR"
                     /locus_tag="ACL70N_000347"
     CDS             complement(1285..2562)
                     /gene="spxR"
                     /locus_tag="ACL70N_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGS0589228.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2555..3106)
                     /locus_tag="ACL70N_000348"
     CDS             complement(2555..3106)
                     /locus_tag="ACL70N_000348"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589229.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3122..4381)
                     /locus_tag="ACL70N_000349"
     CDS             complement(3122..4381)
                     /locus_tag="ACL70N_000349"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS0589230.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            4524..4649
                     /locus_tag="ACL70N_000350"
     CDS             4524..4649
                     /locus_tag="ACL70N_000350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589231.1"
                     /translation="MKIKDQTRKLAAGCSKHCFEVVDGTDVVSILHIRQGDIDVI"
     gene            complement(5431..5589)
                     /locus_tag="ACL70N_000351"
     CDS             complement(5431..5589)
                     /locus_tag="ACL70N_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589232.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5599..6909)
                     /gene="obgE"
                     /locus_tag="ACL70N_000352"
     CDS             complement(5599..6909)
                     /gene="obgE"
                     /locus_tag="ACL70N_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGS0589233.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(6973..7107)
                     /locus_tag="ACL70N_000353"
     CDS             complement(6973..7107)
                     /locus_tag="ACL70N_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGS0589234.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7166..7342)
                     /locus_tag="ACL70N_000354"
     CDS             complement(7166..7342)
                     /locus_tag="ACL70N_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS0589235.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7373..8698)
                     /locus_tag="ACL70N_000355"
     CDS             complement(7373..8698)
                     /locus_tag="ACL70N_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0589236.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8714..9757)
                     /gene="cpoA"
                     /locus_tag="ACL70N_000356"
     CDS             complement(8714..9757)
                     /gene="cpoA"
                     /locus_tag="ACL70N_000356"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGS0589237.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9872..10201)
                     /locus_tag="ACL70N_000357"
     CDS             complement(9872..10201)
                     /locus_tag="ACL70N_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS0589238.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10215..11324)
                     /gene="rpoD"
                     /locus_tag="ACL70N_000358"
     CDS             complement(10215..11324)
                     /gene="rpoD"
                     /locus_tag="ACL70N_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGS0589239.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11327..13087)
                     /gene="dnaG"
                     /locus_tag="ACL70N_000359"
     CDS             complement(11327..13087)
                     /gene="dnaG"
                     /locus_tag="ACL70N_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS0589240.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13177..13935)
                     /locus_tag="ACL70N_000360"
     CDS             complement(13177..13935)
                     /locus_tag="ACL70N_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589241.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13932..14798)
                     /locus_tag="ACL70N_000361"
     CDS             complement(13932..14798)
                     /locus_tag="ACL70N_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589242.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14867..15871)
                     /gene="trpX"
                     /locus_tag="ACL70N_000362"
     CDS             complement(14867..15871)
                     /gene="trpX"
                     /locus_tag="ACL70N_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589243.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(15984..16201)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16284..18980)
                     /gene="ppc"
                     /locus_tag="ACL70N_000363"
     CDS             complement(16284..18980)
                     /gene="ppc"
                     /locus_tag="ACL70N_000363"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGS0589244.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19000..20229)
                     /locus_tag="ACL70N_000364"
     CDS             complement(19000..20229)
                     /locus_tag="ACL70N_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS0589245.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20373..20682)
                     /locus_tag="ACL70N_000365"
                     /pseudo
     CDS             complement(20373..20682)
                     /locus_tag="ACL70N_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21014..21910)
                     /locus_tag="ACL70N_000366"
     CDS             complement(21014..21910)
                     /locus_tag="ACL70N_000366"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HGS0589246.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVPNDLILKWK
                     SEPKFVWAKNVINELNKTENGRLIIRRIATEFYKMKNIPDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLRQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSPKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            complement(21935..25018)
                     /locus_tag="ACL70N_000367"
     CDS             complement(21935..25018)
                     /locus_tag="ACL70N_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0589247.1"
                     /translation="MIEFGRRSLYFSKLVRSKAKMIEFDIPLESHLPISEDAQKSFLG
                     ALAIVADTARKYFEVYINRKSFNLQLKNQLHNAAEYFDALLVSGLGNSAEYQDYIAIL
                     GTTAYYLCDYNGSSRVMINYISDDIQLLEDCMTLIKVFIDVVTDELFLNHTPIEGKYS
                     SELNTLVESYRNYILSKTEFSIDIYRDLQDKVYRNGSDFSVIIVNCLLAVVCKKINSS
                     STKLLPEFSGLDFSLWQDYIQSTGSIKELWPSQIELGKQGIFSGKSGIVQMPTSSGKT
                     ASINLTLRSAFYSNRIDNALIVAPFRALCREIYRDINAHFVDENNVIVSEVFDLPEIP
                     QDFSIFNDGKKRVFILTPEKLLFLLRNHQSFIDEIGLCIFDEAHLFDDPSRGTNFELL
                     LSTVKQIFPKGIQKILISAVIPNSEAINRWFNEDGVIVSNNSIKTTEKRVAFSDLNGS
                     NEQLYFIDPITFEEEFFVPRTVSVSELEQLGKERKQKVFPELTNANDISIYYGTKLIN
                     NGGVGIFCGRKDTVNVILRRFIDLNNRNYDLTDFLKNSDRSEVEKIGNLIGQNLGYDS
                     VEYTCSQLGVFSHHSGIPMGIRIAIEYAFSKSKINNVVCTSTLAQGINLPIKYLIISS
                     VYQAGDAIKVRDFQNLIGRAGRAGKYTEGTIILTEPNIYKSPKNKWKKQNYKALLNPI
                     NTEGCQSNILSIIQFKSVVPTDYRFAPIKFDFWNLIKERFDSSVDYRTKINNILSKLK
                     RKNSLYFKDFNSKIDQIDNTLIAIENYIASMYATELETDSLAENTFGYFLGNEEEKEK
                     IKELFILIKSKIITSSVETEIIAKNSIGLYQSELLKEWVQENKTSILSCEKEEELLGV
                     LTKKIIDFSNNKEMRKLSIENLNYISQLWIKGISYFQILESCTEKSISIEKRGKSKPI
                     DMSDIISICDNGLGYETSMVLNAINNILEKLVGEELDVLTMLIKRLKYGLPLEKEINI
                     YELGFSDRIVVQVIGQEINSVSKNQIRNEIKQKSARLEDKLSDFPSYYTQIINEM"
     gene            complement(25015..25824)
                     /locus_tag="ACL70N_000368"
     CDS             complement(25015..25824)
                     /locus_tag="ACL70N_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hachiman antiphage defense system protein HamA"
                     /protein_id="HGS0589248.1"
                     /translation="MEKMHSYIKYLTQEDPIITDEGKQIEILHLDIQDDPEIFEDWAK
                     QFRRNYCSDDELAEMIGFMNISPKEYLENFKLPSDSGIGLSTMSGDFGEILVSDYLQY
                     IEEYVVPRTRYDSKVNKNTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSKA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQANVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKNHRDFQKLRLLVIHSNELMKFIRELYSKASEV"
     gene            complement(25808..26584)
                     /gene="pezT"
                     /locus_tag="ACL70N_000369"
     CDS             complement(25808..26584)
                     /gene="pezT"
                     /locus_tag="ACL70N_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGS0589249.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQSIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQENGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNPARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEERMRDMSKSNGKDA"
     gene            complement(26584..27060)
                     /gene="pezA"
                     /locus_tag="ACL70N_000370"
     CDS             complement(26584..27060)
                     /gene="pezA"
                     /locus_tag="ACL70N_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGS0589250.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(27505..27960)
                     /locus_tag="ACL70N_000371"
     CDS             complement(27505..27960)
                     /locus_tag="ACL70N_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589251.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(28235..29974)
                     /locus_tag="ACL70N_000372"
                     /pseudo
     CDS             complement(28235..29974)
                     /locus_tag="ACL70N_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            complement(30137..31021)
                     /locus_tag="ACL70N_000373"
     CDS             complement(30137..31021)
                     /locus_tag="ACL70N_000373"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS0589252.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(31133..31987)
                     /locus_tag="ACL70N_000374"
     CDS             complement(31133..31987)
                     /locus_tag="ACL70N_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGS0589253.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEATYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(32045..32803)
                     /locus_tag="ACL70N_000375"
     CDS             complement(32045..32803)
                     /locus_tag="ACL70N_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS0589254.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDVRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(32864..33052)
                     /locus_tag="ACL70N_000376"
     CDS             complement(32864..33052)
                     /locus_tag="ACL70N_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGS0589255.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(33374..33940)
                     /locus_tag="ACL70N_000377"
     CDS             complement(33374..33940)
                     /locus_tag="ACL70N_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589256.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(34208..35887)
                     /locus_tag="ACL70N_000378"
     CDS             complement(34208..35887)
                     /locus_tag="ACL70N_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGS0589257.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIIEELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYKEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(35979..36140)
                     /locus_tag="ACL70N_000379"
     CDS             complement(35979..36140)
                     /locus_tag="ACL70N_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589258.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQDMKNSFD
                     MAKTQIETD"
     gene            complement(36824..37546)
                     /locus_tag="ACL70N_000380"
     CDS             complement(36824..37546)
                     /locus_tag="ACL70N_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS0589259.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEKDIEIDKEREGEIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
     gene            complement(37673..37818)
                     /locus_tag="ACL70N_000381"
                     /pseudo
     CDS             complement(37673..37818)
                     /locus_tag="ACL70N_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
     gene            complement(38218..38940)
                     /gene="mobQ"
                     /locus_tag="ACL70N_000382"
                     /pseudo
     CDS             complement(38218..38940)
                     /gene="mobQ"
                     /locus_tag="ACL70N_000382"
                     /inference="COORDINATES: protein motif:HMM:NF015354.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
     gene            complement(39250..39567)
                     /locus_tag="ACL70N_000383"
     CDS             complement(39250..39567)
                     /locus_tag="ACL70N_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGS0589260.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(39623..40048)
                     /locus_tag="ACL70N_000384"
     CDS             complement(39623..40048)
                     /locus_tag="ACL70N_000384"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0589261.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(40101..40285)
                     /locus_tag="ACL70N_000385"
                     /pseudo
     CDS             complement(40101..40285)
                     /locus_tag="ACL70N_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(40436..41230)
                     /locus_tag="ACL70N_000386"
     CDS             complement(40436..41230)
                     /locus_tag="ACL70N_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589262.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(41230..42237)
                     /locus_tag="ACL70N_000387"
     CDS             complement(41230..42237)
                     /locus_tag="ACL70N_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGS0589263.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(42237..43244)
                     /locus_tag="ACL70N_000388"
     CDS             complement(42237..43244)
                     /locus_tag="ACL70N_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS0589264.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(43234..44259)
                     /locus_tag="ACL70N_000389"
     CDS             complement(43234..44259)
                     /locus_tag="ACL70N_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS0589265.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(44652..44870)
                     /locus_tag="ACL70N_000390"
     CDS             complement(44652..44870)
                     /locus_tag="ACL70N_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0589266.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(45608..47239)
                     /gene="rlmD"
                     /locus_tag="ACL70N_000391"
     CDS             complement(45608..47239)
                     /gene="rlmD"
                     /locus_tag="ACL70N_000391"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS0589267.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(47313..48287)
                     /locus_tag="ACL70N_000392"
     CDS             complement(47313..48287)
                     /locus_tag="ACL70N_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGS0589268.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(48361..48975)
                     /gene="pmp23"
                     /locus_tag="ACL70N_000393"
     CDS             complement(48361..48975)
                     /gene="pmp23"
                     /locus_tag="ACL70N_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGS0589269.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(48975..49949)
                     /locus_tag="ACL70N_000394"
     CDS             complement(48975..49949)
                     /locus_tag="ACL70N_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGS0589270.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(49957..51213)
                     /gene="glyA"
                     /locus_tag="ACL70N_000395"
     CDS             complement(49957..51213)
                     /gene="glyA"
                     /locus_tag="ACL70N_000395"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGS0589271.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(51275..51706)
                     /locus_tag="ACL70N_000396"
     CDS             complement(51275..51706)
                     /locus_tag="ACL70N_000396"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589272.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(51708..52310)
                     /locus_tag="ACL70N_000397"
     CDS             complement(51708..52310)
                     /locus_tag="ACL70N_000397"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGS0589273.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLSEISFEEA"
     gene            complement(52294..53133)
                     /gene="prmC"
                     /locus_tag="ACL70N_000398"
     CDS             complement(52294..53133)
                     /gene="prmC"
                     /locus_tag="ACL70N_000398"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGS0589274.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(53133..54212)
                     /gene="prfA"
                     /locus_tag="ACL70N_000399"
     CDS             complement(53133..54212)
                     /gene="prfA"
                     /locus_tag="ACL70N_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGS0589275.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(54209..54799)
                     /locus_tag="ACL70N_000400"
     CDS             complement(54209..54799)
                     /locus_tag="ACL70N_000400"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGS0589276.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            54923..55105
                     /locus_tag="ACL70N_000401"
     CDS             54923..55105
                     /locus_tag="ACL70N_000401"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGS0589277.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            55242..56615
                     /gene="mnmE"
                     /locus_tag="ACL70N_000402"
     CDS             55242..56615
                     /gene="mnmE"
                     /locus_tag="ACL70N_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGS0589278.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(56662..57597)
                     /gene="dapA"
                     /locus_tag="ACL70N_000403"
     CDS             complement(56662..57597)
                     /gene="dapA"
                     /locus_tag="ACL70N_000403"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGS0589279.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(57653..58729)
                     /locus_tag="ACL70N_000404"
     CDS             complement(57653..58729)
                     /locus_tag="ACL70N_000404"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGS0589280.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDMDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(59071..59143)
                     /locus_tag="ACL70N_000405"
     tRNA            complement(59071..59143)
                     /locus_tag="ACL70N_000405"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(59108..59110),aa:Thr,seq:ggt)
     gene            complement(59243..59752)
                     /locus_tag="ACL70N_000406"
     CDS             complement(59243..59752)
                     /locus_tag="ACL70N_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGS0589281.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(59750..59846)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            59875..60306
                     /locus_tag="ACL70N_000407"
     CDS             59875..60306
                     /locus_tag="ACL70N_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGS0589282.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            60388..60765
                     /gene="mscL"
                     /locus_tag="ACL70N_000408"
     CDS             60388..60765
                     /gene="mscL"
                     /locus_tag="ACL70N_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGS0589283.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(60807..61901)
                     /gene="hemH"
                     /locus_tag="ACL70N_000409"
     CDS             complement(60807..61901)
                     /gene="hemH"
                     /locus_tag="ACL70N_000409"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGS0589284.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            62055..63278
                     /gene="pepT"
                     /locus_tag="ACL70N_000410"
     CDS             62055..63278
                     /gene="pepT"
                     /locus_tag="ACL70N_000410"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGS0589285.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(63314..63968)
                     /locus_tag="ACL70N_000411"
                     /pseudo
     CDS             complement(63314..63968)
                     /locus_tag="ACL70N_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            63966..64130
                     /locus_tag="ACL70N_000412"
                     /pseudo
     CDS             63966..64130
                     /locus_tag="ACL70N_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(64207..64850)
                     /locus_tag="ACL70N_000413"
                     /pseudo
     CDS             complement(64207..64850)
                     /locus_tag="ACL70N_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672611.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(64957..65517)
                     /locus_tag="ACL70N_000414"
                     /pseudo
     CDS             complement(64957..65517)
                     /locus_tag="ACL70N_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672571.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(65743..68862)
                     /gene="phtE"
                     /locus_tag="ACL70N_000415"
     CDS             complement(65743..68862)
                     /gene="phtE"
                     /locus_tag="ACL70N_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGS0589286.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNLADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(69072..>69500)
                     /locus_tag="ACL70N_000416"
     CDS             complement(69072..>69500)
                     /locus_tag="ACL70N_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGS0589287.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDETEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT        20427 a        14308 c        11289 g        23476 t
ORIGIN      
        1 gttagttgtt tacttgcttc atcattcata gaactactat accatatttt gtttcgcagg
       61 aagtataata taaaaaaata aatttaagat tggcaataca aacgttaaac agaattccat
      121 ttctcttttt agaatcaaaa cgacaatatt gtggaatctc tacaggaaca atagactgcg
      181 acactaaaat atcctccctt agttttactt tactaatagt atataggagg agagccctga
      241 atcctagacc ctttgttatg atgcgcttac aaacaaagtt ggaaaaaatc ttaaaagcag
      301 aaaaacgcat gatatcagcc cctaacactt gatacaatgc gttttattat gaaaagatct
      361 actggatttt ttatcaaaat aaacttccag tagtcttttc actttttatt aataagttcc
      421 ttcttcacct tggctagtca agataacagg tccatctttc gtaatgacaa attggtgttc
      481 atactgacat gacaatccac cgtcaatggt cttatgcgcc caaccagttt tcatatctgt
      541 atcaatttcc caatcgcctg tattgatcat tggttcaatg gttaagacca ttccttcacg
      601 aagacggagt ccacgacctg caataccata gttaggaacc attggttctt cgtgcatagt
      661 tgggccaaca ccatgaccaa ccaaatcacg cactacaccg taaccacgac tttcagcgta
      721 ttcttgaata gccgcaccga tatcaccgat acgatttcca acaacagctt gctcaatacc
      781 cttgtacata gcttctttgg ttacatccat caagtttttg acttcttcgg acggtgtacc
      841 aacagcataa gcccaacatg agtctgctaa accaccagaa tagctctgag tgtatttttt
      901 catttgttca acattgttga agtttaattt tgagacattc aggtcggatt tagcaatggg
      961 acctcccaaa accatatcaa ctttgagcaa atcaccatct ttcaagatat aatgacgagg
     1021 gaaagcgtga gccacttcat cgttaagaga gcaacaggta gcataaggat agtccatcat
     1081 ggcaccgtca accccaatct gaagtggaag gaaattttct tctttacaac gacggcggac
     1141 atattcttca acttcccaca tatctacgcc tggcttaatc aaatcacgta agcctatatg
     1201 aatacttgct agaaaatcac cagccttgtc catagcttcg atttcacgag ctgattttaa
     1261 tgttatcatc ttttctccta gtttctaatt aattttaaca gtcacatttg cttttgaaac
     1321 aatctggtga ccatgataaa tatcgtaatc aattatagct gaccgtctcg tatgatgaat
     1381 aatccgtgcc tgaatgcgca atatatcatc tatctgaaca gcctgcaaaa agtagatcag
     1441 catctgctcg ataatgagat tgcgaccact attaacaact aaatcttggg tcatgtgggt
     1501 cagaatttct gccaatacac cattagccaa aactccattt ttttctagca taaagggttc
     1561 cactgtaatg actacttcat catggtgata agagagcttt tgtccaatct gctcagaaaa
     1621 agttggtaga gccgaaactt gggaacggct catcttctcc atgacatctc gtcgcgtcac
     1681 aacgccaagc aaagtttgat tgcttcgaac aactggtacc atttcaaagt cttctgcgat
     1741 catccgttga ctcacattgg caatatttgt cgataatcca accaaaaata gactacgaga
     1801 cataacctta tcaattgtcg tgcttggtga tttatcacca gcgtctctca tggttacaac
     1861 gccaacaacg acctgatgtt gattgataac agggaaacgg ctgctacgat tcttacgaac
     1921 caagtccaaa taatctttaa ctgtatctgt ctctctcaga aaaccatact catgactagg
     1981 gcgataaagt ttctcaactg tcagaatatc agtcttgatt tggacatttg acaaggcttt
     2041 attgatcatg gtagcgacgg taaaggtatc atgcttactt cttagaacag gaatcccttt
     2101 ttgattggcc agtttaagca catcatcatg aacctgaaat ccccctgtaa ccagaactgc
     2161 attttcattt tccaaggcta gcaactgaat acgggttcgg tctccgacaa tcaagagccc
     2221 cccatcatga aggtaagaca agatattttg ttcagtcatg gcaccaattg aaaacttact
     2281 aaattctctc tctaaacctt cttgcccagc cagaacctca gaagaagtca cttctgcaat
     2341 ttcagcaaac gttaatctat ctatagcaac tttctgggat ttaacacgaa ttgttccact
     2401 tctaggacgg gtctccacaa ttccacggtt ttcagcttct ttaatagctc gataggctgt
     2461 tccatcacta actcctagat gattcgaaat gctacgaaca ctgacccttt tacctactgg
     2521 taattcctcc aaatagctta gaatttcctg atgcttactc attgaactct ccttttacat
     2581 accgaaattc aagataatcc cgcatttttc ttgtgtaacg atcacttccc ttaaactgac
     2641 ggaacaaact aaatccagac ttaagagcaa ctctttggct agcttcattt tcaaggtggg
     2701 taatgataaa taattgtttt aagccaaatt cctcaaaaga aagctgacaa atttttctaa
     2761 caacctctgt cataaatcct tgcgaccaag catcttttct caaaaaatag ccaagctcag
     2821 cttctttttt gatttcatct aacttctcaa atttaataga accaatcatt tgttgatttt
     2881 tctggtcaca aattgcccac actcccaaag gggacttcat aaagtaattg gccagtgcat
     2941 attgactttc ttccagactt gcctgcgttg ggaaaataaa ttgaagattt tctggatttg
     3001 aagctatctc gcggaagtcc tgactatcac taaaaaagaa aggacgcaaa tacaagcgat
     3061 ccgtttcaaa aaaagaaaac attgctaatt tggtccaaat attcataaac acctctacgg
     3121 tttaatcctc aacaagtcta atatccgctc ctaaattacg taatttttcg ataatatcag
     3181 aataaccacg taagataaac tcgatattgg taatttcagt tttaccttca gccataagcc
     3241 cagcaatgac tagtgcagcc ccagctctta agtcggtcgc tttaacactg gccccacgta
     3301 aatcacgtcc acccgtgtac aaaatatgac catttgttgt cgaaatatcc gcatccatct
     3361 ttgctagttc aaaaacatga tttacacgtt tttcgtaaat cgtatcgaca attgtaccac
     3421 gaccattcgc tcttagtaaa agaggggtaa gcggttgttg caaatcagtt gcaaagcctg
     3481 ggtaaggagc tgtcttaata ttgattgctt tcaaattaga ctgttcctcg acaaaaatgc
     3541 tgtcctcaga tacagtcatt ctcactccca tttcttccaa cttagcaata aacccttcca
     3601 ggtgttcgta aagaacatta tttatacgaa ttcctttacc aactgcagca gctaaagata
     3661 tatatgttcc agcttcaata cggtctggaa tcacctgatg acgtgtccca tgtaatcttt
     3721 caacaccatc aataatgatg atattagttc ctgccccacg gatatgggca cccatattat
     3781 tcaagagagt agctacatca ataatctcag gttcacgggc tgcattttca ataatagtac
     3841 gaccatttgc tttaaccgca gcaatcatcg tattaatcgt tgctcccaca ctaaccgtat
     3901 ccatgtaaat acttgcacca tgaagtcctg tatctttagc agataacttc atgttatctc
     3961 cctcgtagct agcagtggca cccatagctt caaacgcctt aaggtgtaag tcaatcggac
     4021 gaggaccaag atcacatcct cccggtagac caactgtcgc ttcaccaaaa cggcctaaga
     4081 ggctcccata aaaatagtaa gatgcacgaa gactgttaat tttaccataa ggcattggaa
     4141 tattttgaac acctcttggg tcaatctcca atacatcgtc ataacgctta acagtagctc
     4201 ccatcaattc catgatttcg acaagactgg ctacatccga aatatctgga acgcaatcca
     4261 aagtcaccac atcatcagcc aagataatag ctggaattaa ggcaacgaca ctatttttag
     4321 caccactaat agtgatttca ccttgcagtg gtaatccacc attgataaca atttttctca
     4381 ttctaagttt tcaatactct ttcaagattt ctaataaggt cttcaaaata aagtatatca
     4441 taaatttatc cttttttcca tccttttcaa ttttattgga taaatcagag ttgacgagtt
     4501 agtaactgaa ttactaatac tcaatgaaaa tcaaagatca aactaggaaa ctagccgcag
     4561 gttgctcaaa acactgtttt gaggttgtag atggaactga cgtagtcagt atcctacaca
     4621 tacggcaagg cgatattgac gtgatttgaa gagattttcg aagagtataa tctttctcga
     4681 atcgctattt cccctttttt atcccctaaa actgagtagg agctaagact agatctctta
     4741 tctaagtatc ggaatacggc tgttcaacta aattttagca agaacttctc ccccttctct
     4801 cagttcacag aagcgtttta tacataccgt cctatcagac aatctatttt aaagataacc
     4861 gtgactcagg atcacttcta tctgtcgttt tctctttata gtgatagacc tcacgggata
     4921 agtcgtacat ctttcctcgt gtatacaaga tataaggacg ttaaaagctt acagtgaaaa
     4981 tagaaaatct tagtacgaat tcaattactc tcgtgattta cgcatatagg ttacgactac
     5041 ctttttggac tttagagttt gaggccctct tatccgctat atacgcctta ttatcacgtt
     5101 cctgttcgta gagccacgat ttcgctatcc cttcttctga caattcttat ttccagcgtc
     5161 agacttaaaa cggtctatcc ccagaccatt ttaatccgct acctcacgat agtcaggctt
     5221 gggaatcgct atttgactcg ccgagaactt tgacatcaga tatactataa caaattgaga
     5281 taagaatcaa acaatttaat tttgaaattc aaatcaattt ataacaatat tttagaagat
     5341 atgctgtgct attccagatt cagtttgcta tacatgcctg tcgtaccaca aaatcccgtg
     5401 tctgatgagg cacgggattt tttagcttct ttactgagat ggattttcct ttttagttcg
     5461 tgccaatctc aaggcacgat ttggattgag acgattaaat agttcttcca atttcttttc
     5521 attccaaacg tctgcggcgg aaacaaaatt accatccgca tctcggaaag atatcggttt
     5581 atctcccata ccagtctcct agtctacaaa ttcaaactca aatttaccaa tgcggaccaa
     5641 atccccatct ttagctccac gcgcacgaag ggcttcatca acccccatac cacgaagctg
     5701 acgggcaaat ttcatgacag attcatcacg atcaaagttg gtcatattaa agagtttcat
     5761 gagtttttca ccagaaagta cccatgtcgc atcgtcatca cgactaattt caaaggcttt
     5821 ttcttcttcg tcaaatccat agtaagcttc ttcttccata tcggactcgt cgtagagcaa
     5881 aaattctggt gtcttgtcta acaattcagc tgtagcatct aaaagtgttg ccagaccttg
     5941 cttggtcaat ccagaaattg ggaagatagc tggtaactct tcaaattcat cataattttc
     6001 agacaatttt ttcttaaatt cttcaagatt ttcctgactc tcaggcatgt ccatcttatt
     6061 agctacaata atctgtggac gctccatgag gcgaagattg taagactcca gctctttatt
     6121 gatagctagg taatcctcat atggatcacg gccttcgcta gctgacatat caatgatgtg
     6181 aaggataaca cgtgtacgct cgatgtgacg gagaaactga gttcccaaac caacaccttg
     6241 actagcccct tcaatcaaac ctggcaagtc ggctactgca aaggattcac ctgattgggt
     6301 gcgaaccata cctaaatttg gtacaatagt ggtaaagtgg taggcaccaa ttttaggctt
     6361 agctgaggta ataacactta aaagtgttga cttccctaca gatgggaatc ctactaaacc
     6421 gacatctgcc aagattttta gttccaattg taactcacgt tcctgacctg gttctccatt
     6481 ttcagagatt tccggtgcag gattttttgg tgtcgcgaaa cgaatatttc cacgtccacc
     6541 acgaccaccg tgggcaacga taaattcttg cccatgttca atcaaatctg ttaaaacctt
     6601 gccagtctcc gcatcacgaa cagtcgtacc ttgtggtact cgaactctaa ggtcctcagc
     6661 accacgacca tgcatccctt tggtcatccc tttttcacca gaatcagcct tgaaatgacg
     6721 attgtagcgg aaatccatca aggtacgtag tccttcgtct acaacgaaga ccacattgcc
     6781 tccacgacca ccatcaccac cccaagggcc tccattaggg acatattttt cacgacgaaa
     6841 ggcaaccata ccatcgccac cattaccagc cttgacctta atcttagctg tatctaaaaa
     6901 catactcatt atttcttctc actttaaaaa agggctggga aatcccagtc actaaatttt
     6961 cttgaatcta ttttatagat tactgagggc accaattgca gttgcaaaaa ttcccaataa
     7021 acttgctact agcatgataa tcacgataaa caaggttatt ttctcaaaca tagttttttt
     7081 acgatttcca ttatctccaa atgccatttt tctctccttc gttacattct attttctatt
     7141 atcttagcat gaattgagct agttttcaat agtcagttgc tactggtgcg ataatccata
     7201 aaataatgta agctacaatt ccagctccgt aacagcaagt aagaacaccc caaatgactt
     7261 gaacgatagt cggatccata tccagataat gggccacccc agcacaaaca cccgcaatct
     7321 ttttatcacg accgcttctc attaattgtt tttttcatag ctgttcctct ttctattctt
     7381 catggtcttt ccaatagtct ctcatactga tcaactgtgt ttttgaagcc ttcaacatgc
     7441 gtctagatcc ttttacaggt acagcaacca cctgttgcgg aagatacaaa actgtcctaa
     7501 agatacgctg actgaccgta tcatctttag ccaaatcttt ctggaagtta tttgaaataa
     7561 tggcatccag ataaaactca tgcactcgtt tcccaaagtt ctcagctgaa atctcataca
     7621 atttctctga taaggtatgc tcattcatgt ctggtgttgc aatcagggct tccaaaatag
     7681 caccagccaa atcatgttct ccatagtaca aggctccaaa cattttatca ctgatgaggt
     7741 tgttcaaata aggatttccg tgagcaatga caggtgttcc actggctaag ctttccaagt
     7801 aggtcaaacc ttgcgtttcg cttgtcgatg ccgaaatgaa gaaatccgcc gctttatagt
     7861 aaagagccgt ctcactagga gcaatcatcc ctgtaaagat gactgagtct tgaatctcta
     7921 ggttctgggc ttgctctttg aggtcattca gataagggcc atccccagct actaccagtt
     7981 taaccttgtc ttcctctttc agaacatcag caaaggctgc taaaactgct tgaatatttt
     8041 tttcatagga gattctcgaa agactaagca acgtcttttc accatcttga atccctagtt
     8101 tactacgcag ttctttcaaa ttttcctgct tgatttccgg acgctcaaac ttggctaatt
     8161 caatcccagt aggaatgacc cgtttttcaa ccttgacctt ataatcagat agcaagtcac
     8221 ggacaatctc actagggcaa ataaccccat ccacatcatg caggaaacct ctaaccagat
     8281 acttgaccat actcggccgg atcaatatcc ccttagcaat ataatggaca tagtcttcat
     8341 actgggtgtg ataggtatgg atgactggaa ttttcaattc acgcgcaatc caaatcccca
     8401 acaggccaag agaaaattct gtctgagtat ggataatatc tagctgatac tgtttagcaa
     8461 tttcaagtgc cttgctaaaa cctcggtagg caaagcgacg atccttaaaa gcaaagaaag
     8521 gaacacttgg aatgcggata atttgccaat cttcgtagcg attgacatcc ttatctgtcg
     8581 tcgtaaagat aaaaacagca tgtccctgct tttcaagttc tgttttcaag gttcgaatac
     8641 tggtcgcaac accagaaacc tgaggaaaat aggtatctgt aaataaacca attcgcatag
     8701 attacctcac tttttacttt ctccctaaag cggcttgttt ctcataaaag tccaaccaga
     8761 tttgtaacag atgctcttca gaatactctc tggaaatatt cttagccttt tctttgagat
     8821 cttttaagac agcaggattt gcttgatatt ccaaaatagc ctctttcatc tcttctctac
     8881 ccgctgtcgc ccgataattt ccctccaaaa tcaccttata gagatctaaa tcacgcaaca
     8941 taataggagc ctcacaactc gcagcttcta aaatagtcat aggaaagagc tcattgtaac
     9001 taggcaacaa gaaaagatcc gctagagcat acaattcgcg catccgctct ggcgatacaa
     9061 tgcctggaaa aatcaaattt ttagggggat tttccataat tttcttatag tgttcataac
     9121 catctgtcat accaccaaaa gagaagccac cagcccagat aaaggtaatc tgaggcaatt
     9181 cctcagccag acggataaag tcatcaatcc ctttacgttt ctgaacttgc ccagcaccta
     9241 ctacgataaa ctgattgtca ctaagaccaa gatctgtgcg cagtctgact acctcttctt
     9301 gtggtagagg atgccatttt tccttgttga caaagttagg aatataggtc actttttcac
     9361 gtggaatacc agctgctacc aaatcctcaa taaacatagg attgaccaca accaagtgct
     9421 ccatccggtt gtaaaaagaa aatacatagc gtttcacaat tccctttaag aaaaatggaa
     9481 ttttcaaact tccttcaagt gtagctggca agaaatgcac atagccaatc tttctccctg
     9541 agcgtttctt ttggaaggtt gataaataat agggaaaatc aatcgtatga aagtgagtca
     9601 catctgcctc gattggaaga ttttctgtaa caatcaattg gtccttggca gcacggtgaa
     9661 gaagacgaac taattcacgg taagcacctg aaactccctg tcctgctact ttctcacttg
     9721 aactcaacat attgatgcgt aatttctttt tctccataac tactattata tcattttctt
     9781 tgaataaaat cagcaaaaga aaggagagac tagaggaaaa gaggggaaat ttcctcgctt
     9841 ttcctctagt ctctcacatg cttttatatg tttacttaat gcctagggca atgcgggcat
     9901 agcgactcat tttttcaact gtccaggctg gataccagac taatttaacc tcagtatccg
     9961 ttacttctgg aacctctatc atagcatcat aaatctggtc tgtcaaaagg tctgctaagg
    10021 gacaacccat agttgtcaaa gtcatgtcaa tctctgtttg ccctgtgtca ccgtcaaaac
    10081 gaatctcata gatcaaacca agattgacaa tatcgattcc caactcaggg tcgatgactt
    10141 cttccaaggc tgttaaaatc cgtgttttga tgttttcaat ttgctcttct gtataagcca
    10201 tattttcctc actcttagtc ttcaataaaa tcacgaagcg gtttgctgcg acttggttgg
    10261 cgtagttttc tcaaagcctt tgcttcaatc tgacggatac gctcacgagt tacgttaaag
    10321 actttcccca catcttcaag tgtgcgcatt tttccatcat ctagtccaaa acgtagacgc
    10381 agaacatttt cttcacggtc tgtaagagta tctaagattt catccaattg ctcacgcaag
    10441 acgatacgag tcgtataatc cactggattt tcaatcactt catcttcgat aaagtctcca
    10501 aggtggctat cgtcctcttc accgatagga gtttcaagag atactggttc ttgggcaatc
    10561 ttcaagattt cacgaacctt atcaggtgtc atatccattc gttcagcaat ctgttctggt
    10621 gtcggatctt gccccaattc ttgaaggaga ttccgctgtt cacgaaccaa tttattgata
    10681 gtttcaacca tgtgaactgg gatacggatg gtacgagctt ggtccgcaat agcacgagtg
    10741 atagcctgac gaatccacca agttgcataa gttgaaaact tgaacccttt agaatagtca
    10801 aacttgtcaa ccgccttcat caagcccata tttccttctt gaatcaagtc aaggaactgc
    10861 atgccacgac cgacatagcg tttggcaatg gaaacaacca aacgaagatt ggcttccgca
    10921 agacgttgtt tggcttcgat atcgccagct tcaacagcca gtgccaactc tttctcctct
    10981 tcattggtca agagaggaac gacccctatt tctttcaagt acatacggac agggtcattg
    11041 accttagcag aagttgatcc aatcaagtcc tcatcgctga gttctggttc ttcttcattg
    11101 ctaagaacac gcgcacttgg atttccttcg ttatctgtga tagaaatccc tgcatcctga
    11161 atccgttgca agagatcttc aatcccatca gcgtccaagg taaaaggaat aaccagactt
    11221 gcattgattt catcatctgt tgctgtccct ttttgcttat gattacggat aaattctgct
    11281 acctgtacgt caaatgttgt tacttctttt tgttttgttg ccattattac tccattcttc
    11341 tcttttggga aattaaacgt tccaattctt ctagggctgt atctgtatct cctacatggc
    11401 tagcttcctg caccttcttt ttgattctca tattgtcctg attcaagaga gccttgtttc
    11461 gagtcatctc tacttcacta agttcctgcg gcgatatctc agcaggcaaa tcctgagcta
    11521 aaacttggta ccaagctctt tcaacttcct ctgtctgctc tgctaaaact tctggaggaa
    11581 gatttccata ctggccaagc aagtcatata agacctgaaa ttcaggtgta gcaaatgcaa
    11641 agtcttctcg caaacggtaa tcgttcaaaa caagagggga ttccatcatc cgatagagta
    11701 gatgggcttc tgccctcata atagccgata actgcttggt gacaggcatg gtgattggcg
    11761 tcggtctgga aattctttcc atgcgattct gcctttgcac ctgacgactc tcattaacaa
    11821 tctgctcaat ctgggtataa tcaaaggacg ccagactgtc agctaaaata tgaatatagc
    11881 tgttttgagc agcgatggac ttttcttgaa caatcaaggg agctattttt tcaataaact
    11941 caatctgagc ctgcagattt tcactgtttt caggtttgta ctgatgaatg tagaactcaa
    12001 tcggactaat acgagttttt gttaatagat aggccaagtc ttctggacca tttttttgta
    12061 gatactcatc aggatccaag ttatcaggca tgctaacgat ttgcacaggc atatcaccaa
    12121 tttcatccaa tgctttcaat atcgcggctt gcccagcctt atctccatcg taaacaagaa
    12181 ccaatttctt ggttaacctt ttcagatgct caacatgctc tcgactcaag gccgttccca
    12241 tcgacgccac agcattttcg attccagccc gataggctgc aataacatcc atgaatcctt
    12301 ccatcaggta aatctcacta gtttttccag aagatttttt tgccctatcc atatgatata
    12361 attcgtaact tttgttaaaa attgcagtcg atcggctgtt tttatactta gaagtttgtg
    12421 aatccgtttt ttgccagata cgacctgaga aggcaatgac ctttccttgg tcatttgtca
    12481 ggggaaacat aatgcgattg tgaaaggtgt ctacaaattg attggcatcc gagagataaa
    12541 acaggcctga atccagtaaa tcctcttcac gatactgatc agacaaacgt tgatagagat
    12601 agtttcgttc tggaggtgct aaaccaatcc aaaaatgttt aagcacttca tctgtcaaac
    12661 cccgctgata aaggtaattt ctggcctctt cgcccatagt cgttgtcatg agaatagcat
    12721 ggtaaaattt agccgcatct tcgtgcatat cataaagagc ttggtgaggc gaggctggct
    12781 tctgttcact ataaagcggt ttttcaacct caatcccgac acgctgacct aagatttgga
    12841 cagcctctat aaagggaacc ccttggtact cctcgatgaa tttaaagaca tcacctgagc
    12901 gaccacaacc aaaacagtgg taaaactgct tgtcctctac aacgttgaaa gaaggtgttt
    12961 tttcaccatg aaaaggacag agccctagat agttccgtcc tgccttttgt aaagaaatca
    13021 catctcctat gacttccaca atgttggcat tgtttttgat ttcttcaatg acttgtttgt
    13081 caaccataca caatacctcc atgttatcat agtttacttt atatagtata ctttatttca
    13141 gaaaaaaagt aaaccatttc actcattttc cctactttat tcaaagagtt gataataatc
    13201 agagattttc atttttgctt tttcttcttg gtttaaatct tggataatcc gtccttcttt
    13261 catgacaatc aagcgattgc cgtatttgag agcatcttcc atatgatgag taatcataag
    13321 ggctgttagc tgatctttct taacaaattc atctgtcaat tccatcaaag caacactagt
    13381 ctttggatcc agggcagcag tatgctcatc taacaggagt aattcaggtc gcttcaaggt
    13441 tgccatcaag agactcaaag cctgtctttg tccacctgat aagaactcaa tcggtgtatt
    13501 caagtgtttc tcaagaccat ttcctacttt ttcaatggtt gcctgaaatt catccttata
    13561 gctagtcaag cgtcgtggta acaatccacg cttctcacca cgaaacttgg cgattaaaag
    13621 attttcagcg accgtcatac ggggagctgt ccccatcttt ggatcttgga agacacgaga
    13681 caggtacttg gcacgcttct cgggtgaaaa cttagtgaga tcttcaccta aaatacggat
    13741 agttccacta gttagtgata aggtccctgc tatagtgtta aagagggttg attttccagc
    13801 accatttccg cccaaaatcg tgataaagtc ccgttcaaaa atttctaagg aaacatcatt
    13861 taaaataatc ttttcttcat caaagccatt tttaacaatt ttggttgcat tttttaattc
    13921 tacaattgct gtcatttgct taacttggct cctttcaaga ttgtttgctt aaatgttgga
    13981 atcatgaggc agactgctaa aatcaaggca ctgtataaac gaaggtaact tgtattaaag
    14041 ccaagtgcga taactgccca cactaaaaat tgataagcga tagaacctac aacgatagta
    14101 accaaacgct ctgccaagct caaactcttg aaaataactt ctccaataat caaacttgca
    14161 agccccacaa cgataacccc gatccctcga gacacatcgg catagccttc ttgctgagca
    14221 atgagggcac ctgcaagggc aatcacacca tttgataaga ccaagcccat gagctccatg
    14281 cgtccagtat gaatcccgaa acttctagcc atatcaggat tatcccctgt agcaatatag
    14341 gcttgtccga gtttagtgtc caagaaaaag agcatgagag caataacaat gctcacaaag
    14401 atgagacctg tcaagagttg attcaaatcc gaatcaaaag gcaaaacatc ctgaatttgc
    14461 ttggttccaa gcaggcctaa attcgcacgt cccataatca agagcatgat tgagtgacaa
    14521 gaagtcatca ccaaaatccc tgagagcaag gttgggatct tcccttttgt ataaagaagg
    14581 cctgctgcca ttccagccaa acaacctgct cctacagcaa caagtgtcgc taaaaatggg
    14641 ttcacgcctt tggttatcaa agtgacagca acagctcccc caagagggaa ggaaccttct
    14701 gtcgtcatat ctggaaagtt taaaatccta aatgtcataa agattcccag acctagaata
    14761 gcccagacaa atccttgaga aataatggaa acaatcatat tttatttaat cctttctata
    14821 ttcatctttt taaaaaatgg gaagagtctc ctcctcccta ccttatttat tcgatgactt
    14881 gtcctgcttc tttgagaaca gactcaggaa tagtaatacc tagttcttgt gctatttttt
    14941 tattgatgac tgacttacca gttgaaaaga cattgactgg ggtatcggct ggttttgcac
    15001 ctttcaagac ttgcacaatc attttacctg ttgccacacc aaggtcatgt tggtcaatta
    15061 caactgatgc caaaccacct acttctacca tagctgtcgc actgggataa attggtttct
    15121 tagaactttg attgctagag acaaccgttg gaaatcctga tgcaatggtg ttatcaattg
    15181 gaacccaaat agcatctacc ttgatagtca taacagtgac agttgaggca atttcatttg
    15241 ttgaaggaac tgcaaatgtt tccactgtca gacctgcttt ttcagcataa gccttaaatt
    15301 cttcaacctg tgtttttgaa ttgtcttcgc tacttgagta aagagctccg attgttttca
    15361 cattcggtgt cagagccttg atgagttcaa tttgttgttg agctggattg tggtcagata
    15421 cccctgtaac gttaccacct ggttttttca aatctttaac caagttagca ccaattgggt
    15481 ctgtaatagc ggccatgata actggtaggt cttttgttgc actagccaac ccttgggctg
    15541 ctggtgttgc aataccaacc acaaggtcat tcccatttgc aaccaattgt ttactcattg
    15601 tcgcaacctt actttgatca ccttctgagt tcataaaatc aattttaact tgatcatctt
    15661 tatatccttc ttctgcaagt ccatcttgga tccctttata aatcaaatca agggatggat
    15721 ggctcacaaa ttgaagcaca ccaatcttgg ttattttctt ctcatcctta ttattctgag
    15781 cttctgattt attcattgaa gaataaatca agcttcctgc tactaagact gctaatgcag
    15841 caataattcc aattaaacgt ttatttttca ttctgtttct cctttttatt tcctttaaca
    15901 tatttcactt atctaaacaa gcgacgccat cgttttcttt ccatactaac ctccatcaaa
    15961 aaaatcctca cacaaaaaac ttgtgtgagg acgtcgatgc gcggtaccac ctcaattata
    16021 gggaatttcc ctatcgctca gtctcgcaat aacgagatgc actgtaaggt gtgcttaccg
    16081 aatttttata atttcaaatt ctaaatagca ttcagcccaa ttttcatcat cgccacttat
    16141 ctgttttcag ctaccacaga ctctctaaaa agtttgtatg attacttttc tgaatggtta
    16201 aattatatca tttttaaact acttgtcaat agtctattag aatttttttg atattcactt
    16261 ttagcattca ctcttgaaaa ttatcaacct gaattacgca atcctgtcgc aattccgttg
    16321 atggtgatat gaatcaatcg ttcttgatca ctggacaatt ctccacgacg ttggcgttta
    16381 atcaactcta actgaatata gttgagaata ttaaagtaag gcatacggta atccagacta
    16441 gcttttagat atggattgtc agctaagagt tcgtcatgtc cttcaatagc caagataacg
    16501 ttcttagtaa cttgccattc atttaaaata gtctcataga tggccttaac ttgctcgtct
    16561 tcacaaagtt tagcatattc aaaagcaata ttcatatttg attttgacaa aaccatatca
    16621 acatttgaaa gaagcgattg gaagaaaggc caattttggt acatatctcg taagatagca
    16681 atattctctg gatttttatt gataaattcc ttgaagcttg aaccaacccc gtaccatcca
    16741 gggaacataa cacgactctg tgaccatgag aatacccaag ggatggcacg caaaccaccg
    16801 atttcagtaa tagtcttacg agcggctgga cgagaaccaa tattaaaact tgaaatagcc
    16861 ttgattggac ttgactcgaa gaaataatca tagaaatgct cattaccaaa gaccaaatca
    16921 cggtagatat cgtaactacg gtccactact tgatccataa tggcttcata acgatttggg
    16981 gtattggtat cgctcttctt ctgagtaatc atacggttaa tagctgccga tactagcatt
    17041 tcaaggttat agtaagcggc gtctttgtta ccgtatttat tcccaattac ttcaccctgc
    17101 tccgtcaagc ggatacgatc cttgatagac ttgagcggtt gagatgtaat ggcttcatag
    17161 gttggcccac caccacgacc gacagtacca ccacgaccat ggaagaaggt aaccttaacg
    17221 ccaaattcat ctccaatagc agtcaattgt tgttgagcct tgtagagggt ccaacatgat
    17281 gacaggtaac cgccatcttt attactgtca gagtagccaa gcatgatttc ttggtagtta
    17341 tttcgtgagt caatccattt tttggcaagg ctaagagaaa gatattttct cattgtttcc
    17401 tctgaatgat ccaagtcttc aattgtttca aaaaggggaa caatctgaac acgcgccctt
    17461 tccgtatcca ccagtcctac ttcttttaac agaatagcta attctagcat atcagaaagg
    17521 ctggttgcat gtgaaatgat ggtctgacgg atgacatcat ctcccaactt atctttcaaa
    17581 acacgagccg tcttaaaaat agctaattct tttgctaata attctgattt ttctgcgtga
    17641 gtcgcagaaa gaattcgggg atcttcttct aattctttca agagaaggtc acacttttct
    17701 tcttcgctca actcgctata acgagaatga attcctgctg atttcaagag ttctgccaca
    17761 caggcttcat agacgctaga gtcttgtcgc atatcaattg acgctaagta aaaaccaaat
    17821 atctctactg cctgcaataa ttccacaaaa tcacctgaaa tcaaggactc acccttattt
    17881 tctagtagag aatctcgaat ggcaatcaaa tccttgtaga aatcattggc ggtttcataa
    17941 cgagtcccaa cttcttcatc ctcaatcaga taggttttag ttgcctgaat ttttgattga
    18001 atatcaaaca aggcacgacg gtaaagctct ttttcgcggt aaatcgagtt atccttggat
    18061 tgacgagcca tttctctgac ttgcttgctg acgttgacaa tgctagttga aagagaaaat
    18121 tcacgataaa gttggtaaat ctttttatca tagtagttca tgatgacttc acactgagtg
    18181 agtgcagact gcttcaaggt ctttgctgta acaaatggat ttccatcacg gtcaccacct
    18241 atccacatac ccatggtgat tggtttagcc tgttttaaat tcagaccatg cgcttgcgct
    18301 aagcgcttat actccgtcgt caaatgaggt acagctttca aaaaggagct gttataatat
    18361 tccatagcat tcgtgatttc gttagtcact tttaattttt tctcacgaat catgtctgtc
    18421 tgcatgataa tttcgatgta acgacgcaaa tcattgtacc atttatcttt attaatcaac
    18481 cccaacttaa catcacggta tttacgcaaa agactatgaa tatgatttgt taaatccaac
    18541 atacttttgc gttgcacttg tgttggatgg gctgtcaaaa cagggacaac attcaagtgt
    18601 tctaggatct caacggcatt ttccttttct gctaccaatt taatcgttgt agataattta
    18661 cctaaatagt cctgatcaat attattttga tgattgattt cataagctaa atccacatcc
    18721 tctgaaatat taatcaaaag aggcaagata gagaaatagc gtgaaatata gaccatttca
    18781 tcatttgata agctagtcac tagacggttt agaccttgat aatcttcctg cgttgataat
    18841 tctttcaact gtattatttt ttcaaaggtc tctggggcaa gcatattttt agtaatatct
    18901 tccagtaatt ctgttagaat caagacttct tcttgcacaa cacttttatt actataattt
    18961 tctaattttt gaagagacat aaactatcct ttctttatcc tacttcaaca gaaggttcat
    19021 tggttgattt tccaattctc ggtacaattt agcgcgtttt tcactggcat caatatttaa
    19081 gacaaaggct actgccactg ataagactag aagactattt ccaccctggg ataagaaggg
    19141 gaaggttact cctgtagatg gaatcaagcc cgaaatccct ccgatattga caaatacctg
    19201 aaccaacatc atccctccga caccgagtgc aaccatggca ttgaaaggat tctccgctcg
    19261 gataccgacc aagataatcc gcaaaatcat gaaaaataag agagctaaaa taagactggc
    19321 accaacaaag ccaaattctt caatcacgat agaaaagaca aagtctgtat gagcttctgg
    19381 caaataacct cgtttttcaa tcgagtttcc aagacctaga ccaaaccaac cgccattgac
    19441 catggcaaaa taagaattag ctaactggtg acctgcatca gcacgatcgg caaaaggatt
    19501 aaaaaaggca ctaaagcgct tggctacata gccaaatact ggaatttttg aaaaggtctc
    19561 aacaccgatt aggctgatag tggtcaagac aaagacagaa gcggcagata cgagcgccag
    19621 aatggttgaa aaccagcgat aagcgattcc actaactgta tacataatca aggaaaccaa
    19681 gactaaaata gtcgcatttc ctaaatcagg gaaaattccc aaacttccaa tcagaactag
    19741 gagaacgaat cgccaatcat taaaagcacg gggaagccat tgattttgag tcaaaacttg
    19801 aaaatcataa gtagctattt cttcttgctg tttggagaat cggtgagcta aataccaaat
    19861 aataatgatt tttaagtact cagctggctg aatagttatt cctgcaaccg aaatccaacc
    19921 gtatgccccg tttacggaaa taccaataaa acgagccaag aacaataaaa gcatttctat
    19981 taatataact aaaatgatta gtcgctcatt tctcaaaaaa tctagtctca atttataaat
    20041 taaggcaatc agtatcaaac taacaatcca aaagattcct tggtttcgaa ccaactgcaa
    20101 ggcgctcttg ccttcttcaa ttaaaatagc actggtggtc gaatagacca caatcaagcc
    20161 caaaatagat aaaagcaagt agggaatcaa gatggaataa tttaataagt gcctcttact
    20221 aatcttcata gtatcaccac tctactagga tacagacaaa tctgttccaa attccgtttt
    20281 attttctagt tttgattgct attataccat tttttcagaa agaaaaaaac tcttacctta
    20341 caatccttcg aattttactg tttttacaga attaaggcag aatttgaaat cgtaaaacca
    20401 ttttgaataa gagttgcttc aatccattga ctccgactaa ttatgttgct ttcgtgaatg
    20461 ccaaaatcag ccgcaatttg ttcataagtg tgctattctc gcatgtattg aatagttacc
    20521 atgaggagat cgtctaggct taatttggtt tttcgtccac cttttgcgcg tttacgttgc
    20581 gttgataagc tgtttttaac acagctaaca tctcgtgcgc tgaacaccta caaggctctt
    20641 gaaacggcta tcgcttaatt gtttacttgc ttcatcatcc atagttttat tgtattgtat
    20701 ttttgtttcg caggaagtct attattcctt tcgttccaag gtttttacgc ttttagcaac
    20761 aagcttacac actccacgtg atgcgtctgt ggaactcaaa aggttcgggg aaccttttga
    20821 ggattaattg cgtttctcta acaaactcac acatttaacg tggcatgact gatgaagtca
    20881 tcataagaat ttcacttgct gctcttttac gatggcagcc tgaacggtca gaagtatcat
    20941 tgtatatcat ttgtatcatg gcatataaag tatcgctcta ttttattgat ggttttaata
    21001 tctctcggaa aagttattct tgattaatta tagaaacatt tggattgcca gttttagaag
    21061 caccaattat cttaactttt aaagcttcgt acaaactaat tctattttct agaatataag
    21121 ctaattcttg tccatccata aataaaattt tagcatcttt attagaaaaa tcttgtatta
    21181 cttcatctct aaaaccattt attgaaagaa acagtccccg agtcgaagtt agttttgtat
    21241 caactttttg ttttaaagaa gctattttcg gagaatttac tggatttttt tcccatttca
    21301 tttcaactaa ataatcaaaa ccttcaaacc taaaatagcc atctaactgt tgagtatttg
    21361 ttctatttct atacgaatca tggtaatcaa tatcattaat tctgaataaa ttagcaacaa
    21421 ttttttctaa acgatatcct ctttcttgag gattatcact tgaaaatagc gaataatact
    21481 ccgtctttag ttcttcaatt ttttgaagga gttgttgcct gagttgtatt ttcatttcct
    21541 gtctggaacg atgataagaa ttattaagtg tttcgttaac cttattctgt tgagtatcac
    21601 ctatcagtcg ctttaatttt cttaacgcat ctaatcctct atctctatct tgaacttcat
    21661 caggaatatt tttcatctta taaaattcag ttgctattcg tctaattatc aatcttccat
    21721 tttctgtttt attaagttca tttataacat ttttcgccca aacaaacttc ggttccgatt
    21781 tccattttaa tattaaatca tttggaactc ccgaagtttg cataaatgaa acgacagtat
    21841 ctttatagtg aaaacataat ccaaaacatt gaataatttg ttgttggatt tcaaaagata
    21901 ttttagtcat tttttctcct ttttatcaac aatattacat ttcattaatt atctgtgtat
    21961 aataacttgg aaaatcactc aatttatctt ctagtctagc tgatttctgt ttgatttcat
    22021 ttctaatttg attcttactt acagaattaa tctcttgacc aataacttgg accacaattc
    22081 tatctgaaaa acctaattca tagatattga tttctttttc cagaggtagc ccatatttca
    22141 gcctctttat taacatagtc aatacgtcca attcctctcc aactagtttt tcaagaatat
    22201 tattaatcgc atttaaaacc attgatgttt cataccctaa tccattatca caaatagaga
    22261 ttatgtcaga catatcaatt ggttttgact tacctctttt ctcaatacta attgattttt
    22321 cagtacaact ttccaatatt tgaaaataag aaatcccctt aatccagagt tgagaaatat
    22381 aatttagatt ttctatactt agttttctca tctctttgtt atttgaaaaa tctattattt
    22441 tcttggttaa aacacctaat aactcttctt ccttctcaca agaaaggata gatgttttat
    22501 tttcctgaac ccattctttt aataactcag attgatataa tccaattgag ttttttgcaa
    22561 ttatttcagt ttctactgaa ctggtaatta ttttagattt tatcaagata aataattctt
    22621 ttattttttc tttttcctct tcattaccta agaaatatcc aaatgtattt tcagctaaac
    22681 tatcagtctc caattcagta gcatacatag aagcaatata attttcaatt gcaattaggg
    22741 tattatcaat ctggtctatc ttagaattaa aatccttaaa ataaagactg ttctttcttt
    22801 ttaattttga taaaatatta tttatttttg ttctgtagtc tacagaactg tcaaatctct
    22861 ctttaatcaa attccaaaaa tcaaatttta taggagcgaa tcgataatca gttggaacta
    22921 ctgatttaaa ctgtataata ctgagaatat tactttgaca accctctgta ttaataggat
    22981 ttaacaatgc tttatagttt tgttttttcc acttattttt tggtgattta taaatattgg
    23041 gctctgttaa aattattgtt ccttctgtat attttccagc ccttcctgct ctacctatca
    23101 aattctgaaa atcacgaact tttattgcat ctcctgcttg atacacactt gagataatca
    23161 agtatttaat aggtaagttt ataccttgtg ctaaggttga agtacatact acattattta
    23221 ttttactttt tgaaaaagca tactctatag caatgcgtat ccccataggt atacctgaat
    23281 gatgtgaaaa aactcctagc tgactacatg tatattcaac actatcatat cctaaatttt
    23341 gaccaattaa atttcctatt ttttcaactt cagacctatc tgagtttttt aagaaatcag
    23401 ttagatcata atttctatta tttaagtcta taaatcttcg taaaataaca ttgaccgtgt
    23461 cttttcttcc acaaaaaatt cctactccac cattattaat tagcttagtc ccataataaa
    23521 tacttatatc atttgcgttt gtcagttctg gaaaaacttt ttgtttgcgt tcttttccaa
    23581 gctgctctaa ttcactaaca ctaacagtac gtggaacaaa aaattcttct tcaaatgtaa
    23641 taggatctat gaaatataat tgctcattac tcccgtttaa atcactaaac gcaactcttt
    23701 tctctgttgt tttaatcgaa ttattagaaa caattactcc atcttcgtta aaccaccgat
    23761 ttatagcttc actatttggt attacagcag atattaaaat cttctgtatt ccttttggga
    23821 aaatttgttt aaccgttgac aacagtaatt caaaattggt tccacgactt ggatcatcaa
    23881 aaagatgtgc ttcatcaaat atacaaagtc ctatttcatc aataaaactt tgatgatttc
    23941 tcaataaaaa caacaatttc tctggagtaa gtataaaaac tcttttttta ccatcattaa
    24001 aaattgagaa atcctgtgga atctccggta aatcaaaaac ttcactaaca atcacattat
    24061 tctcatcaac gaaatgtgca ttaatatctc gatatatttc tctacataat gctctaaaag
    24121 gtgcaacaat caatgcatta tcaattctat ttgaataaaa tgctgatctt aaagttagat
    24181 tgattgaggc tgttttaccc gaacttgttg gcatctgaac gattccagat ttacctgaaa
    24241 aaattccttg cttccctaat tcgatttgag atggccaaag ctcctttatg cttcctgttg
    24301 attgtatata atcctgccat aaagaaaaat ctaatcctga aaattcaggt aataatttcg
    24361 ttgatgaact atttattttt ttacatacaa ctgctaagag acaatttaca ataattacag
    24421 aaaaatcgct tccattccta tatactttat cttgtaaatc tctataaata tctatagaaa
    24481 actcagtttt tgataaaata taatttctat atgattcaac tagagtattt aactcactag
    24541 agtatttacc ttctattggc gtatgattca aaaagagttc atccgttaca acgtcaataa
    24601 atacttttat aagagtcata cagtcttcta ataactggat atcatccgat atatagttaa
    24661 tcataactct cgaactacca ttataatcgc atagataata agctgtggta cccaatattg
    24721 caatatagtc ttgatattca gctgaatttc ctaatcctga caccagcaat gcatcaaaat
    24781 attcagcagc attgtgtaat tgatttttta attgtaaatt aaaactctta cgattgatat
    24841 aaacttcaaa atacttccta gcagtatctg caacaattgc tagtgcccca agaaacgatt
    24901 tttgagcatc ctctgaaatt ggtaaatgac tttctaaagg aatatcaaat tcaatcatct
    24961 ttgcctttga acgcactaat tttgaaaaat ataatgacct tctcccaaat tctatcatac
    25021 ctcactcgct ttcgaataga gttctctaat aaatttcatt aattcattag aatgaatgac
    25081 caatagtcgt aatttctgaa aatctctgtg attttttgaa actactgtct tgataacatc
    25141 aatatcatat gattgattgg agtagactgc aacagctcca tagattacat taaacggttt
    25201 atccgttatg tttaaaaatc tttctactac atttgcttga tcactattag atttctttaa
    25261 cctcaaatag ctggctacaa ttgaggttga aaatcgttca aaatctttat cagaatgatt
    25321 aatagcttct tgaagcttat ttttcgcttt agagctacta gaatctgatg cagatgattt
    25381 tacttcaata actacaacct catcattcga cacattcgaa gaatcttgct tatatcctag
    25441 aacatcactt ccttgagttg aagtattttt attgacttta ctatcataac gagtcctagg
    25501 aaccacatat tcttcaatat actgaagata atcagatact aatatttctc caaaatctcc
    25561 tgacatcgtt gaaaggccaa taccactatc cgagggtaat ttaaaatttt caagatactc
    25621 tttaggggag atattcataa aacctatcat ttcagcaagt tcatcatcag aacaataatt
    25681 tcttctgaat tgttttgccc aatcttcaaa aatttctggg tcatcttgaa tatctaagtg
    25741 aagaatctca atctgcttac cttcatcagt aataatagga tcttcttgag ttagatactt
    25801 tatataacta tgcatctttt ccattacttt tactcatatc cctcatccgt tcttctccca
    25861 ccttcaacat ctcttcctct accttgctcc attttccgaa gaggtattct tgtagcactt
    25921 ctgctgctga agttgtattt tcttttgaat catatacaca acttctatct cgttggtaaa
    25981 tttgaattct ttcaaaaata gctagttctt ccaattgtcg tgtattatca actagatgat
    26041 ttacaatgaa atcatgatgt tcttttggag ttgcgcgtgc tggatttgga ttgatagcat
    26101 acagttcttc gtatcggata agggtgctca gataggacaa ttcgggcttg gttgcaatta
    26161 aggctaattg tacctcatac cccttatttt ttaatagttg tgctgttttc tttggaacat
    26221 caatagttcg taaagttccc tctatcaaaa gattgtatcc caaatgactc aattcggtta
    26281 ctaaagactc taccattttc cctgcaaaat ctttggtgta ttcaacgcta tctttgccat
    26341 tttcttgctg cagttctaaa tagtgtggat gctgagaacg aaaactatca ccatctatga
    26401 taacaatatt tccttgaaat tctttctgtt taatacgatg aattgtagtc ttaccggcac
    26461 cactttgacc tccaagcaaa atcgctatag attgtttact ggactttttt cctcttgtca
    26521 gtgaacgaag attccttgct aaagcatgtt tgaattcact atcagtataa tcttggattt
    26581 ccattaagct accatccgct tttcagatat ctctaacata cgttcaattc catccaaata
    26641 gccgctatat ctctctattt catcaaaatt ttctactaaa tagatatttg tctgaatcaa
    26701 gtcagataga tcatcactca ttaaaatcca aggattagat tcatcatcaa tgctaattcc
    26761 ctgactatct tgataacgat agagtcgaga taatagatta gcacctcttt ctttcacaat
    26821 ttcaattttc aaagtcaatt cataatcttc aacaggattg agcattttat cttctcctac
    26881 aatatcgaca taagatacat taaacttctg acaaatgatg tcaattaatt ccgtagagac
    26941 tgaactagtt ccattttcat aacgactcaa gctatttcga gaaattccta taattcgtgc
    27001 aaattcgtgt tgtgttaagt catgtgtttt acgtaaggat tttatgtttt ttccaatcat
    27061 ggcaaactcc tttattttta taaatccatt atagcataaa aaagcataac gcaccaaaaa
    27121 tggtgcgtta ttgactgttt ttctatccta aactttactt ctataaaagt cacctaaaga
    27181 gccataaata tttattcttg tattaatttt ttcgatgcgc aaacgatatc tacaaataca
    27241 tctataacga ttcacctttt aggattttta ttgtcaaaat tgcctttatc tacaaagaca
    27301 aaatgcttat aaaatagctt gaaatcaagg attatcacct ttttcgttgt agcaacactc
    27361 cacatgtgat tattaggcta ttagcaaagc gtatccaata cctcaataaa gtgttgtttt
    27421 tactgatatt ttaactatat tgtatagtct actatttaaa tctcaattag gatattttat
    27481 agaataccca aaattcaaca ataactaaaa gtaagattcc attgtatttc cttgttggtc
    27541 tttcatatca cgaattttat ttttcagaat attaaagtta caaatttcat ctctaatatc
    27601 gttatccgct ctgtagccat taatcatctc agtcagagtt ttccctttac taccattctt
    27661 tatagtagta tttactcttt ttatactgct ttcaaaaggc tcatatgttt tatacttaat
    27721 tacttcgtct ttaaaattaa ataaaggtgt atccggctta gcattccata aaataatcaa
    27781 ccacattata acattataaa gctgctttgc agtttcattc cacttttcag gttgtaaatt
    27841 tccactccct gtattgtcat attcttgtct attatttaca tgagaatcac ctacaagcgg
    27901 attaaaaaga ggtagccctt tgtgattaat tagttctaaa aaatcccttg ccgcacccat
    27961 gcaacactga ataacttcct tcttgccatc aattttactc tcagcgataa atacataata
    28021 ttcatcttca atagttgctc ctgcatcact atgtttttgt tgatttgcta acagcttaat
    28081 atgtgcttta ggctaaactt caaaatctct aacaattctt tgtcttgttt catgtcctct
    28141 acaattcatt taagttctcc tttacaagtt tagtaactag ccttattata ctatataaga
    28201 tatgaaatgt accataatct tcatcaacta gtttttagaa aatcacaaat ccatctggag
    28261 agatgacaag ctgattctcc aattcttggc aattgcttgc tagtactact gcttctttct
    28321 ctaaaagata atcttctgtt gattggttga atattgcttt gaggatccgt ccttcgtatt
    28381 tccattccag agctactaga tcagatttga tttcttgaag gctatacttg ccatgcgaaa
    28441 tgattactga cgcgtatttc cgaatcttaa tcagcctctt cataaagttc agcatatcat
    28501 tgtcacttga tacacgttcc caaggcatac aacgacgaca atctggatct ggtcctccag
    28561 tcaaggctag ctcggttccg taataaatgc acggtgttcc tttttgtaaa aagagaaagg
    28621 ctaaggctga tttaaccagt tgaacatctt cattggccgt ccacaggatt cgctctgtat
    28681 catgtgaatc caagagatta aacatgacct ctgaaatctg ctgcttgtaa tacatagact
    28741 ctccattgat ttcatcgatg aactggtctg tattcttaat tcctcgtaag aaatagtcct
    28801 tgatactatc agataaagga taattcatga cggcatggaa ctcatctcca tttagccaag
    28861 gctgagatgt atgccagact tctcctagga tataaagatc aggattttta gctaaaactg
    28921 ccttacgaaa atccttccag aactgatggt caatctcatt agccacatcc aaacgccaag
    28981 catcgatatt aaactcttca atccaataag tcgcaacctt taaaagataa ttcttgacct
    29041 ctggattggc tgtatttagc ttaggcatat agtcctcgaa accaaaaaca tgatagggta
    29101 agtctctctt attaactagc ttttcagttg tcactgggaa ttgttgaata tggaaccaat
    29161 ccttataagc agactgttca ccatttttga cgacattttt tcattgaaga gattgcgaac
    29221 caatatgatt aaataccgca tccagcatga ctttcatgcc acgatgatgc gcttgatcca
    29281 ccagttcccg aaaggtctcc ttgtctccaa aatgacggtc aatttcaaag taatctgtcg
    29341 tattgtactt gtgattgctt gtagattcaa agatgggaca aagatatagt ccagtaatac
    29401 ccaagtcttg caagtaatcc atatgatcaa taatcccctg taaatcacca ccaaagaaat
    29461 catcactctt aggtgtgaca gatgaatccc agtctaaagt cccttctggg tttaatagag
    29521 cattgccatt ggcaaatctt tcaggaaata tctgatacca taccgtattt gaaaccccgt
    29581 caggaacctt gcaggcatca atctcatgaa gataaggcaa cttaaatcca ttcccaattg
    29641 catgaagatt ttctagagaa ttttccacac accctttatc gccatacaaa atattttgac
    29701 cttctgtatc tctgagctca aagagatact ggatacgtgc aaagtcaact gacacttcaa
    29761 cctgccaatg gtcaaataag gtaccagaag ttatcttgac catttctttt gtatcctgat
    29821 aaaactcctc cataaagata aaagggtccc catagtgcaa gttgatgctt tcaatgtccc
    29881 ctttcttagt tcgaattcga atatggagtt tcttatcctt ataaagatag gcatactccg
    29941 actcaggccc atggtaaata gcacttaatt ccatcaattt gtctcctaaa gtattcattc
    30001 aaattttacg caaacgtttt caaactcaat aaatccagta tactattttt gtaaactatt
    30061 tgcaaggaat gtccgttgtt aaaggaacta tcttttaaag tatacaaaaa gccttaaaaa
    30121 aggctttctc tatatactaa tcctctttcg gttttgaaaa tacttctact cgctgagcta
    30181 ggactttgat ttctacaggt aggttatctg atttatctcc gtcaacatct gactccaatt
    30241 cactatctga agagatttta atattacgcg ctttgatata ctcgatatta tcatttgcga
    30301 taacatcccc ttttaataaa tcaggaatga cggataattt ggagaatata gaggcatctt
    30361 tcagaatcaa aatgttggca tagccgtcct tgttttcttc aaagattttc ttatcagcga
    30421 agtaatttgt caaaaggacc aaaacatggc tagcttcacc aacataattt ccattttctg
    30481 tctcaacctt aatgttaaag acctgatctg tcatgacaga cttcatggta tttacagcat
    30541 aggttaaaat accgaatttt gttttgtcct ctatttcaac attgtgaatc gcctcaggca
    30601 gagaaccgat actaaagata taaccaaaat agttgtcatt tgctttaccg atatcaatct
    30661 tattggttaa atcaaaatcc agttcgtcaa ttgcgccatc gatgtcttga ttgatttcca
    30721 aaagttttgt aatgaggtta cccgtaccgc ctgggataat ccctaactta ggaatgtagt
    30781 ctctctcatc aatacctgaa atgacttcat tgacagttcc atctccacca aacacaacca
    30841 ctgcatcata ctgctcacga gaagcttctt cagcaaaatg tgttgcatcc agcgcttttt
    30901 cggtaatttt ggtttcaaca tattcaaagt attcttttgc tttattctcc agcttttctt
    30961 tgtaatccaa agccttctcg ccaccagaag tagggttgat aattaccatt gcttttttca
    31021 ttgattttat ccttaatttt aaacagaaat gtttacattt cgtcgtatgc aagtaaatgt
    31081 aatcctatta tacaatgaaa atacagaaaa gagaaatctg acgtactgga gattaatacg
    31141 cttttattct attttcccat cgcctaacta catcctttaa gggttcatcc aagtaagaat
    31201 aggccttatc cttgatccaa tcaggaatac cgtaagttgc ctctgctatg ctacaagtga
    31261 ttgctgcgag agtatcactg tcgccaccaa gtgagatggc atttcttatc gcatcttcga
    31321 agtctctact ttcaagaaag gcgataatgg cttgagggac agtttcctga catgtttcgt
    31381 taaaacgata gttaggacgg atttcatcta aagtttgaga tagattgtaa tcgtattctt
    31441 tttctatata atccttaatt cgtcttttac actctgtagg attgtcgtta attgattgct
    31501 cgtactctct acaataacca ccaaagtaaa aacgacatag aaagatagca tcagctgtag
    31561 ccatagcgcc tttgacacct tctggatgat tatgagttac ctctgcagaa agactcgtaa
    31621 gtcctctaga tgatggccac ataccagttt tcgcataaaa accacagtcc atgatccaag
    31681 cacatggaga aatacgcata gctgatccat tcccaaagct attataaggt tcacggttat
    31741 cgctgtttag ccatgcatta aaccgagcac cgtaatcagc attcggatac attctgccat
    31801 atttcttcat cgcgtcaatg aaatcgtctt tttgtccacc attcataatt gcttctgcaa
    31861 cagcacaggt cataaccgtg tcatctgtaa aaaagcagtc cttccgaaat aaaggaaagt
    31921 cctttgtttt gatattgttc cattcgtaaa cagaaccgac aatatctcca ataattgctc
    31981 caagcatcag attcctcctt gttcattttg atgcttttta tattggttat ctaccatatt
    32041 tattttagaa aataacatcc tgttggattt taaaaatttc atttttttca aaatagggtt
    32101 ttaccatttc tttccaccta gctctatgaa aattgattga ttttaaagga gataggccat
    32161 aatttcccaa tgcataacca tcatttactt caacaacaag tgttctgcca tcgcgagtaa
    32221 caccgatatc tagtccataa gctattggcg catctttcca acatgatatc gcttcatcaa
    32281 ttacacttgc atcaaattgt gcatgataat cacctgtata gggtcgaaca tctaatacgc
    32341 gaacatctaa cacaaaacaa cgccattcag ctatgaattc tacaacctca ctaatccata
    32401 taggatagtc gaaaggtaga ccaataccta ttaaatcatg ggttccatta acaactcttc
    32461 cagtaaagac ttttgaacca gctttaggct taataaattt tccccaatta tcaggtatat
    32521 tcacaatctc tcctaaaata ccagcataaa tctttcgacc ataaaactct ttaagctcaa
    32581 taggatagtc ataaaccgga acgtttaagc ccatcatttt tagtaatgct ctagtctcca
    32641 ttatataatc tacaactata tcttcacttg ttaactcttt tatttcagaa aaagattgat
    32701 ataaaataac ttcttctcct tgtaagtagg cacctacttg agcattgtat ttattaattg
    32761 aaacctcact tggtaattta ctttgtctaa tataaacaac catttcatca ctcctatatc
    32821 actagtgtta caccaatttg taaaaataat agcaattttg ctcttatttt tttgagtaaa
    32881 tagcccccat aatatcatcg aaataatcaa cggtatttag gagtaattca ataacctggg
    32941 actttgttag tcgcattccc cttctatctc tagcatcttc tactaaattt tcaagtttct
    33001 ctagattttt atcatccaaa ctaatcatta ttctattttt atcggttgcc attttcatca
    33061 cctcaagtta attctatcac aggtgtaaca cttgtgtcaa ctggctttta taatacatta
    33121 gtttaaaagt ggagaggatt ttttacacag taactttaaa tctttggtat taaaaaattt
    33181 tcacaatatt tatagaaata aaatctgtct caaatcagtt atcaaatcta gtataaatta
    33241 tgagcggcta ctctaatact ttccctctaa acaagaaaaa gacttacact caaggatttt
    33301 cttccccccc ttcgttataa cgttttgact cttttactag caaaggtata tactcacaag
    33361 gaactttggt tgactattga atctctccaa cttcttcttt aacatatcct tctacatctt
    33421 caatctctac aaacattggg tctaagtgac acaagaaatg ccaaacttcg atcccttttt
    33481 ttctgtaaag aatcgcttca ccgtcttcac ttccgaaaaa gcttctgtcg atttcatatc
    33541 cgcggctttc taagaagtct tttgctttac gatagttcgt ttctcttgtt tcgacatagg
    33601 ctttaacttc atggttgtta acgacatatg catcaatttt tgaatatcct tcgatcactc
    33661 tatcattttt gagggataaa tttgaaatct ctttccaaat aatgtttaca ttttccccag
    33721 gatcgaacat aaatttagat aaaggaacaa tatttccgtt aaaaataatt tccatataat
    33781 ccggtatgtt tttaggatta aaatactcca cttcaaaacc atcttctgtt tccagagtgt
    33841 atcccgggat ttgagctaca aaggctttcc catcttctat ggaatcaaat gctactaaat
    33901 ctttagaata atcattttgg tacaattcca atataaccat cgataatctc tccattttca
    33961 ttatcaggct aatgtaaata agcacgtcac ctgaccaatt caggctctct gtatcatctc
    34021 atcatatttc ctacttactt tacgagtcct atacccagaa cacaccttat cgaccttcgg
    34081 tctcacctcg tcgcattggc tgaacatcta cttttacttt gctgatgctt caactcgtac
    34141 aagcagtgat accgcctcag cgtgatgcgt cagtgggact caaaaggttc ggggaacctt
    34201 ttgaggatta actacgtttc tctaataaac ttacacattc aacttgttca tcattgtcca
    34261 aacctatgtt gagattttct tctataattg gtagcttaaa agtaatggat tttagccatt
    34321 gtccgttaga ttgtttttct ttataaactt gaatttcaga aatcaaagct gaaattaact
    34381 gcctacgctc tacatcattc atgactttat agagcttatc aaaatagatc agaaccttat
    34441 atatgttatc tcctgtaagc ttttcagctt caatagtctg tttctttgct ttcgcatcaa
    34501 ttagtgatga ttctaattca tctattttgt catacatacg atatagtcta tcatctaaat
    34561 cctgtttcct tctcttataa tgcttatctt caacatctaa attatctatt tcctcaatta
    34621 gcttaaactt tgtagaatga ctctttctca attccttttg gtaattatct atttcttttt
    34681 ctatttcaga ggtatccacc ttcatgttga ttttttcttg catcatagaa gcaaatttcg
    34741 gattacttac tatcttgaca atcacctctg caacagcatc atctaacaat tcttctataa
    34801 tttgcttact gaatgtacac ttatgacctc ttatcatctg cctatgttta caaccatagt
    34861 aataaaaatc tttatacttt gtgccatctt tctttttctt gatacacttg ttcccaaaca
    34921 ttcccactcc acatatcggg cattttacaa ttccagaaag caagtgtgtg cgtgtatctt
    34981 ttcctttatt cacatgctca tatttctttg cttgagattt tagcttaacc tgagcagctt
    35041 gccaaacttc atcggaaact atagcttcat gtatcccttc agatattaga tattcatctt
    35101 gttcaacctg cttatattca tttcttgtac catgaacttt ttctaaagtt cttcttccaa
    35161 atgctatttt cccattatat acaggattct ttaatatctt tcttataaga cctgcatcaa
    35221 acaaaggatt cttaccattc tgtcttggga tttttctaat tccatgattc tctaagtatt
    35281 tagatatccc attggctcct atcgtagtat ttacatactg gtcgaaaatc gttcttattg
    35341 caactgcctc ttcctcattt ataaacagct tgccgtcttc aagtttatat ccatacggag
    35401 caaagccacc attccatttt ccttcccttg ctttttgaat gcgaccttcc attgtttgaa
    35461 tacggatgtt ttctctttct atttcagcca cagctgataa aacagaaatc attagtttcc
    35521 cagcatcttt agatgaatca atgccatctt caacgcagat aagattaact ccataatcct
    35581 gcattatctg aagtgtagaa agaacatcag cggcatttct tgcaaatctt gataacttaa
    35641 acacaagaac aaaagatact ccatcttttc cagattttat atcttccatc attcgattga
    35701 actgtattct accttcaata gacttgtcag acttcccggc atcttcatac tctccaacaa
    35761 tttcataatc gttgtaaata gcaaaagctt tcattcgtga tttttgtgcc tctaacgaat
    35821 acccctctat ctgtattgac gtagatactc gtgtatagag gtatactttt attttttctt
    35881 ttgacatagt attaacctca atataatttt tctatatcat atataatttt tttaatttaa
    35941 gtttggacta tcatttcaag tatattataa cacttttatt agtccgtctc aatttgtgtt
    36001 tttgccatgt caaaactatt tttcatatct tgattttttg ctggcgttgg atcgggtaga
    36061 ttatctaaat ctaaagcacc agcatatttt gcaatcagat ttgctattaa atcagccaat
    36121 ccattccagt cattgtccaa tatatacctc ctctaaagtt ttatatctaa taattatttg
    36181 tttaattaag ttttttgaca ttgacaagtg ctttggatta gcaacatagg aatctcacct
    36241 ccgcctctat tccggatgag ccggcttcaa ccttagaagt atcattatcc tcattttctt
    36301 catagcggat agggtatccc tccctatatt caaactctta cttatcgctc actttctttt
    36361 tgcttagcag aacttttttt gccgaattat tcagccgaaa gatcttgacg gataggttat
    36421 tacgctcaaa aaataattaa cgtcttgtct tggtctattc aattgttaag gttcaaaatt
    36481 tatcgagagt tattaatctt tttaaaattt gaccatcaga aaatatttat cttgatgtaa
    36541 caaaattcta taaattaccc tcttatactt aacagtgaaa agaagtcttt cttggtaacc
    36601 aattttgaaa tagaatttgc ttatataaaa aggttcaatt cccactgcat aagtagcagt
    36661 gaaaattaga ccctcttggt aactgtcatc taaaagtctt ctagcatttc tttaattttc
    36721 taatcgcctt taaagtgtca tatttatatt tttttatctc tggcatactt tgataccttt
    36781 ttagacttaa agtctttaat agtgcctttc cacctctttt tatctataaa gattctccta
    36841 catcataatt cattttttta tttaaacctt tctgtcttag tttgtcttta tcttcttcat
    36901 accattttaa tattgtcaca tagtggtttt gataggtctt accactgctt tccatgtatc
    36961 tggatagttt atttatcatt atatctgtgt gtgagtttaa tttttctttt agatttttat
    37021 attcttcttt gcttaacctt acatttttga attctccata aaaaatgggg gtggactttt
    37081 tatctatctc tccctctctc tctttatcta tctctatatc tttctctatc tcttgtcgga
    37141 catgggttgg actcattaag gacaatgtcc tctgtttatt ttgtctgtat cttctttttt
    37201 tctctgccca ggctgtttct gatccgatta agtttggtat ttcagttagg tagtattcat
    37261 cattttctgt tacaacttct aataagcctt gattgattaa ataatttact gttaccatta
    37321 catcatcgtc tgtttcatct atggttagtg ctaactcttt tataaaatca ctttctactc
    37381 cgtcataata gagtttgccc tcatctttta ggcttagtag tagaagtttt aggtagatta
    37441 tcgtataggt atctcctcca gatattctcc ttaacctttt tatccttttg tctgtgaaaa
    37501 attcttcttt taattttatc caatagtatc ttttgtttgt tgccatatct gctcctttct
    37561 tgattttcga taatcgaaat tcttgatttc cgattttcgg aattctggac ttctgttttt
    37621 cggaagtctt gttattatgg ttatttaagg gtgtaacttt tcgttactcc ctttagattt
    37681 ctctggtcat atcttttttg tttggtttta ctttttcttt tactttcctt tttcttttgt
    37741 cttatctttg tttttggata ggtctttgta tttctttatt tgtttttgga tactttcttt
    37801 ttctttttta tttagcctat aactattaga ctttaaagtt tctatttttg tttgtaactg
    37861 acctatggtt tctatgttgt tttttcttaa ataactatat gcacttgtta gctttttgaa
    37921 gtcatatttt tctttattag tttttgcata tccttttaga tatttacttt tttctttttg
    37981 aatttctgaa taagttaata gataatttgt tagattaaaa agtttagggt tgtctattac
    38041 cttatctctt tcgatatcct taaatttttc ataagcagta gataagttat ctaataaatt
    38101 tcctatccaa ccctttaatg tttttatctc ttcttttatt gtttttacaa gttgattata
    38161 ttttcttatt tctctattat agtttccctt gtcagtttct attccctttc tttccattgc
    38221 acttgctgct gatcctaaat ggattgtcgg tagataatct gaattttgtc ttttaaaact
    38281 cctatggtct actctttttt ctgctcctgc tctttctaaa tatttgttac aaagatctga
    38341 aaaattttct ctccattttt ctacattgcc tgtatcgttc caggttgtta gttctacttt
    38401 tcttgtcttt ggttttccat ttttgtttaa tactttttct cctttttcat ctaggatata
    38461 ttcttttttt gacttggcta agaactctcc tttttcgttt attggtcgca ttatggtcat
    38521 tatatgacaa tggatatttc catttttatc ttgactctca tcatgaattg cataatctac
    38581 tatcattcct tgtgatgtta aattttcttt tatatatctt tcaaccaggt ttttattttc
    38641 acttaaagat aactcttttg gtagtcctat tatgaattgt cttgctagtt gtgcattaga
    38701 atttttttct gccatttcta ctttattcca taaggtagac ttatcattaa attcttttgg
    38761 tatatgatca ggcaatatta tattttttac taatattttt tcttttcttg tgtagtcatg
    38821 ggttactccg tcccattcat tttttatttt ttctccactt atatatgctg cacttgctac
    38881 tgcacttttg ccttttcctc ttgatattat gtttactgaa aaatgaaaac tgtctgccat
    38941 ttttatcact tcctttcttt gttgttttag gtggaggctt aatagttttt ttatatcctc
    39001 tttgtgaatg agcgttttga aatgatagaa ttaaaaaagc cgactactga attaattttt
    39061 gttgtttcag tatgttggct taattgttac tttcatttca aattttaaaa gtcaagggcg
    39121 agccttagcg agtttattta cccttgactt ttaaaaagcg aatggttgtt gctccctgca
    39181 agggtttgac tccgcaggac gcaagcaccc tttagggtgt ataattgcgc ccttgtaacc
    39241 aagggacaat tatgttattt catctttaga tgatttttct acattatcat ctattctttc
    39301 ttctaaaatt tccattatgt ttaatcttat ttcttcatca tttaacgttt ttattaactt
    39361 ataaaattca tcttttgtta aatcaatact ttcttcaaaa atactttcaa acactgcacc
    39421 tttttctata agtcttttgt ttcttgcttt tctttcttgt tcattaagtt ttttcttcaa
    39481 ctgtcttttt tgattttgta attgcttaat gctttcttct ttcttttcaa tctgttcttc
    39541 aatacttaat cttttacttg ccatcatgta tcctttctta aaataaaaaa cgactagatt
    39601 tttatttcta atcgttcttg ttttaaatat tataatttgc tatattgcat tttaatttta
    39661 agtcttctat atatctttcc atgtaattcc aatctggagt acctctactg tctatcggta
    39721 atttaatttt gatatctggc aatactgtgc tagatatttg atctttatat tcagtatttt
    39781 ttaaagcttg cctaataatt gaagttaaat agaatgctac ttctttattc aattctttat
    39841 tttttaattt taaacaatga attttcatat ctaggcttgc tttatattta tgataaaaga
    39901 ctgctcctaa aaatgaaaca gatataaaat tttcaaagac tctataattt ttatcatcta
    39961 tatcttcgta gtaacctaag ataccattgt caatatttgt agcactaatt ctaggagttt
    40021 ttccatcgag taaatatctt tttggaatag atgagcctgt tggtacttaa ctcgatttcc
    40081 cctttttttc ggtaataaat atttcttttt attttgttgt ctgatatttt tcctacctgt
    40141 cctttgtagg atgagtattt tctagatttt cttgaataac tttttacttg aagttttagc
    40201 ttttgaacta gtcgttgtac tttctttttg tttattatca gtcctgatct ttttaatatt
    40261 gctgttattc tctatatcct atttttcatt catgatattc ttttactaat tttatcttaa
    40321 attctgtgct gtatttgcca ttaaaaaact gacctccttt agttagtttt ttggcctaac
    40381 ttttgagggt cagttcaaaa tttgcgactt ttaaatgaat tccaatattc aattattaag
    40441 agttaacatg gtgcttgcca ataggaatca ttagaggcga attggaaata gggtcacgta
    40501 taatttttgc ttcaagatta aagatatctt taactagttt atcatttagt atatcttcag
    40561 gctttccctc tgcaacaagt ttaccttctt taattgcaaa taggtaatca gcgtatcttg
    40621 ctgttagatt tatatcgtgc aaaatcatgc aaatggttgt cttatatttt tggtttagat
    40681 cagtcaagag gtctaatagt tctatttgat atgagatatc caagtaagta gttggctcat
    40741 ctaaaagtag gatacttgta tcttgggcta gggctagagc tatccatact ctttgccttt
    40801 gacccccaga aagttcttca actaggttat ttgctagatc ttcaacattg gccttaacca
    40861 ttgatctgtt tattatttca aggtcatctt ttccaagact cttaaaaggc tttctgtagg
    40921 ggaaacgacc acggcttaca agatcagcta ctgttattga ttcagggatt attggagatt
    40981 gaggtaatat agctatgtgt tttgctaaat ctttttcttt ataagaatta attgatttat
    41041 tatcaagcaa tacttctccc tctaatggct ttataagtcg agacaaggtt ttaatgagtg
    41101 ttgatttccc acaaccattt gacccaataa taactgatat tttttcttca ggtattttta
    41161 tatttatatt ttccaagatt attttttcat cataaccgca ggtaagatta tttgaccaca
    41221 gacctttcat tatatattcc tcctgttcat ttttattagt aagtatatta agtatggtga
    41281 acctaacaag ccagttacaa cacctactgg atatctagct ggtaaaatat tttgagagaa
    41341 tatgtctgat aacaaaacta gtaaaattcc aaccaatcca gctaatattg ggcttctttt
    41401 cttgccaata tttaaggcta tgggaccagc taaaaaagat atacaagcta ttggtcctgt
    41461 aattgaagta gaaaaagcag ttaaagatac agcgcaaaaa attaaaacaa gccttgaaag
    41521 ctcgggattt gctccaagtc cgattgctat ttcttcacca agttcaataa tttctagtct
    41581 tttattaaaa aataaaacta atatagtagc aataatactt actattagaa caagaggtat
    41641 gtcatctaac tttgtaaaag ataaagagcc actgagccat ctcataactt cttgtaattc
    41701 atatcttgct actttcaaca ataaaaatga ggtgcctgct cttgtgacag cttgaaaacc
    41761 aatacctaat attatcagtc ttgctgctga aaaaccatct tttttagcta gtaaaaataa
    41821 tattaaagat gatgttagtc cacaagttat tgaaataatt ccagtagtta aactatttgt
    41881 ttttaatacc aatatgcaaa agaccgctgc aatagatgaa gaacttgtga caccgattat
    41941 atcaggactt gcaagaggat ttcttaacat agtttgaaag ataaatcctg ccaatccaaa
    42001 agaccagcca gctataattc ctgctaataa ttttggtaat ctaatttcca taatcgaaaa
    42061 actagctcca ggaacagttt cactatttaa gactttaatc aaagttgaaa aagaataact
    42121 ttcatctccg ataagtaaaa tgaaaaatga tagactgatt attattaata aaaatagtga
    42181 ggaaaatagt gttattctat tttttctttt ttgaatacct ataattaaat tttgcattag
    42241 ttattaaccc ctctattttt catagttaca taaataagta ctggaccccc gattattgca
    42301 gtaattatcc ctacttcaat ttcacctggt ttacctaaca tacggccgat tatatcacat
    42361 ataagcaaga gctctgcacc tataaaagat gaagaaatgg tcattgtgcg tatatctttg
    42421 cttataaata agccacaaaa gtgaggaact ataagaccta cgaagccaat aggtccacca
    42481 attgcagtaa tacttgaaca taaaagcaca cttgcaatta ttgcaagtga tcttatccta
    42541 ttaacattaa ctccaagacc aacagccatt tcatcaccca tagctaaagc gtttaaatct
    42601 gatgaaataa atatagctat caagtgacct aaaattataa aaggtagtag tgtagatata
    42661 gaagataatg tagctgctcc aaggctacct atttgccaaa atctaaattt gtctaagacg
    42721 ttattattcg gtaaaattaa aaaacttaca aaactgctta aagccatact aacacaagtt
    42781 cctgataagg caagttttat aggggtaagg cctgcttttc cgcttacagc aatcgcgtat
    42841 acaaaaattg cacttactaa gccaccaatg attgcaaaac ttatatggct tatgcttgat
    42901 gaaattccta aaaaagaaag accaattact acactaagac ttgctcctgt gtttataccg
    42961 agtatacctg gatcagctat tgggtttcta gtaactgatt gcatcaatac accgcttatg
    43021 gcaagactag aacctgctaa aattgcaaaa atagttctag gtattctttt atatataatt
    43081 gatttaataa aatcatcatt tgtattaccc attccaaaag ctgctaaaaa atctctgata
    43141 ttaatttctt ttgttccaag ctttaatgac aaaaatattg taataagaag acctaggcag
    43201 attacaaaaa ttatgcctag gtttatttgt tttttatttc gcatttttgc atgcatttcc
    43261 taaaagattt agatattctt caatagtata gtttattgaa agtggtgttg gagtgcatga
    43321 ggctgctaac ggtgtattat ctggaattac agcaacggca ccatttttaa ttgcatttat
    43381 tttacctaaa agaggatctt tttgtaaagc ttcaagagtt ttatcatcac cataagttat
    43441 gattacatca gcatcattta tcttatttgc ttcttctgca gaaatttcct ttgcaaaact
    43501 atcttcactc tcaaattctt ttaatgattc agggaaaact agacctaaat ctgttaaata
    43561 atttgctctt ggatctttgc tagtataaat ccagaatttt gatgtatctg cagcattaat
    43621 catagtaaat aatacttttt ttcctttgat ttttcctttg atttctggat gtttttctaa
    43681 ttctttggat atacgagctt cagtattttt gattaactca tcaccttctt tttccatacc
    43741 taaggctttt gaatcaattt taatcatatc tctccataaa gtttgccaag gtttagattt
    43801 gtatgctgct acaggagcaa tttttgatag agtgtcataa tcttctttag ttataccaga
    43861 ataacctgct aagataacat ctggtttaga atttgatatt gcttcaaagt taagtccatc
    43921 caaatcgtca aataggttag ctttaccatt tagttctttg attttttctt ctgtccatgg
    43981 taaaactcct ttatcagcac ttacaccgta atttgctttt gaaaatccaa caggaactat
    44041 tcctaaagct aatgctacat catgatttcc ccaagcaata gttgcaactc tttcaggttt
    44101 tttatctaat atagtttgac cgaaagcatg atctaaaact attttatcag gcgcatgctc
    44161 tttagaagta ttttcttcat ttttaacaga attagaagaa caagcgctaa aaactataca
    44221 catagctaaa atagctatta gaaaaaattt gtttttcata aaaactcctt aaacatattt
    44281 caagtctatt gtatcgataa taattatcat tgtcaataga tacagttaca aatttaataa
    44341 tataattttt tcaaaaaagg atctagtttt tatttttagt taaattatgt ctatattttt
    44401 cattaactca tcaataaaaa tttgtttgct aatatctctt tcttctgatt ttgtttcaag
    44461 gattattgct acatcattca tatttttagg taaataccaa ccatctggct tatctgaata
    44521 tcccttgaag cctaattgat taaaagtagt tatttgacca gtaccttgat tgatgttttc
    44581 ttcaacttca ttaaagccta tacttctctt gcataatccc taacttgatc ttctgtcctt
    44641 aaagtcattt tctattcctc gtcactaaaa ttatcttcaa aactaataat atcattagga
    44701 gtgcaagata aagccttaca tattctttct aaattcttaa atgtaattgg tttatccttt
    44761 cccatttgtg ccataacatt tgttgtaagt cctgccatag ctattacatc tgttttcttt
    44821 agtccttttt ttgctaactg tatccataat ggtttatagt taagtgccat aatatccctc
    44881 tttttttctt cattagattt atttaattat agcataaata ttgatttcat tcaatcttac
    44941 attgatttag tgatttgttt tagagaattt gttgtgttat tccgtcctta ttttgccata
    45001 aattgtttta agtgggacct cttatcctta ccatttttac ctcctaattt tgagtataaa
    45061 aaagacgata gagtttttaa tttctatcgt ctgagattta catattaaat tttcatcaca
    45121 aaataagact ctttaaagaa tctttaaatt cattggtatg ctaattacaa tatccattat
    45181 taaaatggat actataagca gcacaccaac tatttatttt ttgagtttta aactttggta
    45241 gaagtcttga actccttata tttacataac tatttgcctc tataactatt atgacacgaa
    45301 accaacaagc aagttcaagc acctccatat ctttattcaa atgaggacta agatattcac
    45361 aaactttatc ataaacctct ttatcttttt tcataaaagg ggcatacaac ttagcaaatt
    45421 tatcctaaaa ttttttgttg cctttatcaa tcatttcaac actcctttaa atataaaaat
    45481 gatcctatca atctttatat tgagcctatt ttctaattga taccttgcaa gaaaggaata
    45541 atagctgttc ctataccaag taggaatgta ataaatgcag aaagtcatat actgtcattc
    45601 ttttctatta aatcattttg aagtgtctca aagcatccat gatggcttct tctttttcag
    45661 gtgtacactg tggaataatt tgtttatcct ttttagactt gttgtaatgt tctcgtaatt
    45721 ctattccaca tttctttttt atctgtgcaa tatataatgt cgaaactttt aattcaaatt
    45781 tattccaaac atattctttg atttgagcat atgttgcttt gctctccgca cttgtcaaat
    45841 tcatctcatc cagctcaatt tcaacactta tgtgcttatc gacatcgagt ttggacaaaa
    45901 gtgctaccgt ctcgacgtga tgcgtttgag gaaatagatc caccggctgg actttcttca
    45961 attcatatcc caattcttgg tagagtttga tatcacgcgc catggttgcg acattgcagg
    46021 agatataggc gatgcgatcg gctcctgttt gggcgcttgc tttgataaag ctttctgtca
    46081 agcccttgcg tggaggatca accaagataa cggttggttg aatcccatct ttaagccaat
    46141 tcttcatagc attttcagct gtgtcacaga catagtgggc gtttgaaata ttgttcagct
    46201 gagcattttt tttactattc tcaaccgctt ctggaatcag ttcaacaccg tagacttctt
    46261 tgacatgctt ggcgactgat aaaccaatgg ttccaatacc agaataggca tcaataatca
    46321 cgtcatcttt ttttaactct gcaaagtcaa tggctgtttg atagagtttc tccgccattt
    46381 cagtattgac ttggtaaaag gctgggccag cgatttggaa gtcatttccc aacatctggt
    46441 ccgtaatata gtcttgacca taaagagtgc gccactcctt accaaaaatc gcattggtat
    46501 tctggtcgtt gatattttgc atgacagaca caatctctgg gaactgcttg ataacttgtt
    46561 caatcaattg gtcaacacga aaaacttttg gacgagttgt caccaaaacg accatgattt
    46621 gtcctgaata gtgaccacga cgcaccacaa gattccgaat caatccagac tgttcctttt
    46681 cgtcataagg ttttaaatca aaacgacgga gcaggtctcg aagagctact acgacttggt
    46741 caatgacagg atcctggata aagaaatctt caaggggcat gaggttgtgc gaattcttac
    46801 ggaaaaatcc tgtttccaag acaccattca ctcgacgaac gggcacctgc gccttattgc
    46861 gatacttgac tggatgttcc ataccaagcg tttcagcaac ttctacatct gcaattccag
    46921 caatcttgta gagactgtcc ttgacttgct tggttttaaa cttgagctgt tctggataag
    46981 aaaggtgtcc taaatccgcg attcctgaac gcaggtaagc caaatctaga tcttgattac
    47041 ggtgtggtga ctggacaagg tatttttcaa cttttccaaa gccaatcttt ttattgacct
    47101 tgaggacacg catgagaatt ttttcactcg gtaaagcatt ctctacaaaa aagaccaaac
    47161 catctacctt ggcaactcct gccccttcat gggtcaagtc aacaatttca acttctacaa
    47221 tatcattttt ctttaacatt cttttctctt tctattggcc gacaaaaaag acggcaacgt
    47281 tacggttacc atccattata ccatgaaatt tcttaagaac caaaactctt gaagaagttg
    47341 acaagggctt gccagaggga gcttaagaag ttaccaccgt cctctagcgc cttatccgca
    47401 tcaaagttaa ggttgatatt tttaaaactg tcgccagctt gtgatacgat gctttgttta
    47461 aggtcattta gggttttagt gaaatctgca ttgctgagga tatcactctt tgagagattc
    47521 aaggcaaaat tgatgatgat attgatctgg tttcctgtta tgacctgatc aagtttgtaa
    47581 ttttttaagg tatcttcaac aatcttgcgt acatcttctt ctgtcagatt tcccttgctt
    47641 tctttagctt tggcgagtcc tgacttgata tcagctaggg caacgtttaa tttattagca
    47701 tcatagcctg atttgtcctt gttttcagca ttgatatctg acaaagcctt tagctcttct
    47761 tgagccaaat ctttattggc ttgcggcacc ttggctccat tagcttctag cgaatagtag
    47821 atcccagcca aagcactctc acctgtaact ggaatagggg ctgctacagt gattttggca
    47881 tgttccatac ccagcgttac tgctgcgttt cggtacatat cctgagtcac cttagtgata
    47941 ttttctggtg tttcaatctt gacctcaagt ggcgatttgt cacctagctt ttgaatcttg
    48001 gctgatgaat acaactgtaa gctagagtca ttggccacat tcatgatttt agaataaaca
    48061 tcaggtgtca tggtcttgag ttctttggta tctgttgagg cattgtagcc cagtttttta
    48121 agagtttgat ttttttggtc ttcagatagg gaggaaccta ggacatattc aggttggaca
    48181 taggtttcat cgataacttt ttgaacatct gttgctgcat gggcgctatt catagctgtt
    48241 actgcccaca agaccgcagc actggtcaga aagagtttct ttctcatagg gaatttcctc
    48301 ctttactttt ctagagtaat atatctatct taaagaaaac ttataacaaa aacacctggt
    48361 ctagccagat gttgaaaaga gagtgaaaca tttgatgatg taaaggttaa gtcgtacctg
    48421 tctagaataa taatagtttc ctccatttac atagagttca gcaccgtgaa aaatggaaat
    48481 ggggtgaata taactataag tctttccagt cgtattacca agcaaggggg caacagtctc
    48541 acgagagtac tgtttggcta gagccaaggt attttccttg ccattttggg cgataaaatc
    48601 gatataggca ggtccaaaat tataggcttg aacagctgtc cagatatcta cacccttctt
    48661 ctgcgccaga tagagattgc ctgtcagagt ttgaatgcct tgccgaatgc tagaggcatt
    48721 atcattgatg gtattggtgg aaccacttgc agactcacta gactgcataa catcgccttc
    48781 ttttcctttt gtttcagtat aaatcatagc aagcacaagc tcttcgtttg ctggggtgtc
    48841 tttttcactc aatatttctc gcaccatggg ttgataggtc atgacttgtt tgacatcttg
    48901 atgaacgcgg taagctttat atccagcaaa aaggaagact gctagtacaa gcactcttcg
    48961 aattcgttta aacattattt actttggata tcctcgatat ttttgattaa gatagagtag
    49021 gttccatttt cgttttggat aaactcaaca gactcggcgt cttgatagac gttattggga
    49081 acgatgagct caattccatt tgataaggag agtttttggt tttcaaattt ctttaattgg
    49141 cgactggcat caatttcatc aaattgaaca ggttctggta cggcttcttt gacttggtca
    49201 ataaagctca aacgagccgt cagattgttg tcaaaaaggt cattagccaa tttctcaggt
    49261 gacaattcat tgctttcttc taggttgttg aaaatagctg atttgacctt ggattgaaat
    49321 tgaaaatcat ctgtgttaaa agattcagca attctctggg ctgttttttc cagttccttg
    49381 atagattttt taggagaaat cttaggagcg acagcaagaa gattatctga aaaatagttc
    49441 aaaaaagtcc cgttgtactt gattcgtttt tcaatcaggt gatacttgct actctgaaga
    49501 ttgaccacca aggcctcatc agctcctgtt ccaaatccag gcaggttatt ctgagttagc
    49561 ttgattggat tatcaacttc tcctccgagg tgggtcaagg tctcccgcag ggcaattcgc
    49621 aagaaagcga aatgttctac accttcttta gaaaattgaa caaaaatcaa gtcattggtc
    49681 ttgagatttt cagaaatgct aaactcctct ttccagagat tagccagcgt tactgatgtc
    49741 tccaacaaat cgtctgtaat atgattgaag aagggatttt cttcttcgaa aatcccagtc
    49801 ttggcttcat ctgaatacac atgttcaatt tttttacgta ggtattcttc gatttttgga
    49861 gtaatattga gaaacttatc tgctaagaac agctcggtat catccggact gaactggtga
    49921 ataatggctt tcttaatata aatgtccata aaagttttat tcctcgtata atgggaaggc
    49981 atctgtcaat tctttgactg cacttctcac ttcttctaat acagcctcat tttctgaatt
    50041 cttaagggtt ttaatgatga gttcagccac tttgcgactt tcttcttcac caaatccacg
    50101 tgcagtaata gctgctgctc cgatacgaat cccacttgtc ttgaatggtg acaagctttc
    50161 gtaagggatt gagtttttat ttaaggtaat attgacttca tccaacaagt tttgagcaac
    50221 tttgccgttt tctacaactt tagtcacatc aacaaggaag agatggtttt cagttccacc
    50281 tgaaataata cggaaatcag ggtcttgcaa gaagacatct gccatagcct tgctgttctt
    50341 aattacattg gcagcatatt ccttgaaggc tggatccaaa acttctttga aggaaactgc
    50401 cttagccgcc acaacatgct ctaaaggacc gccctgaata cctgggaaaa tagctgaatt
    50461 gattttttta gcaagttctt cgtcattggt caaaatcaaa ccaccacgag gtccacgaag
    50521 ggttttgtgg gtcgttgttg ttgtgatatg agcgtatgga actgggcttg gatgaaggcc
    50581 agccgcaacc aagccagcga tatgggccat gtccaccatg agcttcgcac cgacagcatc
    50641 tgcgatttca cggaattttg aaaaatcgat aatttgagaa taggctgaag caccagctac
    50701 aatcagtttt ggttttactt cttgggcttg tttcaagata gcatcaaagt ctaagagttc
    50761 cgttttagga tcaacactat aagaaacaaa gttgtaggtt tgaccagaga agctaacagg
    50821 agccccatga gtcaaatgac cacctgatgc caaatccatt cccataaccg tatcacctgg
    50881 ctcaatcaag gacatgtaag ccgcacagtt agcttggctt cctgaatgtg gttgaacatt
    50941 ggcaaattta gcaccgaaaa tttcttttgc gcgttcaata gcaagagtct ctacaacgtc
    51001 tactacatca gttccaccat aataacggcg tcctgggtaa ccctcggcat atttatttgt
    51061 caagatagac ccttgagctg ccataacagc cttggaaact acgttttccg aagcaattaa
    51121 ctcgatatta ttttgttggc gttcttcttc tttggcaata gcattccaga gatcagcatc
    51181 atatgcttta aaatcatctt tgtcaaaaat cataggtctt ctcctttatt gtgtgactag
    51241 tccattagtt tgattttaca ataagaaaat caaactaaca gatgcgaata aaccgtttct
    51301 gcattttatc acaagtatag ccaacttttt cataaaatgc atgagcaccc agacgatgat
    51361 tggcagaatt taagcggata aacccataac cacatctttt tgcttcttct tccaaccctt
    51421 gtagtaaact tttaccaata ccttgacctt gcgcttgagg tgaaactgct aaagctaaga
    51481 tattaaatcc tgctttggaa tagagtgatt cgtaaacttc agcgtggaca tatccaagta
    51541 agacatgatt agctgcatcc tcatagccaa gtaggaaatg atgggaatcc tgagacagtc
    51601 tagctagttg gctagccgtt tcctctggac taaaagtata acccaaagcc tcttggttga
    51661 tgtcacatat cgctttcaca tctgtttctt gcaaatctct tagcatttca agcctcctca
    51721 aaagaaatct ctgacaaccg agcaagaata tcttctcgtt taattgcgcc ttggcgtaag
    51781 attttcacct tgtctccaga caaatccaca atagttgaat cctgtccagt tagaaaagca
    51841 tcgtcttcca gacccagaac ctcttggtca aaatccttca gaatttgttc aaaggttaca
    51901 ccacttgcct gacctgagat attggcagac ggcccaatca agggacctgt ctctcgaatt
    51961 aaatccagtg tgatagggtg actgggcatc cgaaatccaa tagttgcaag gtcagaattt
    52021 acccaatagg gaactcggtc attggcttcg agaataatgg tcaagggacc tggcaaaaag
    52081 gtctctacaa gtttttgtag ataagctggc tgattctttg aaaagtgcaa gatgtcctcg
    52141 aaagaggcga tattgagatt gagtgcctta tctctaggac gacgtttgag ttggtaaaca
    52201 tggtcaactg ctttttcatc taaggccttg gaaaaaagac cataaacagt ctctgtaggt
    52261 agaacgacag ctccaccctt ttccaactct tgtctaatcc tgtccatcat caaccacaac
    52321 catcctattt tgaccaaatt ggtctttgag tgttcgaact cttttttcag gaagatgttt
    52381 tctaaaaagt tcgggaacac tttgaccttg cttgtatcca atttcaaggt aaatcttacc
    52441 accatccttg agatagtctt ttgcatcttc cgcaattcta cagtaaatag ctaggccatc
    52501 ctcgtctgca aagagagcta gatgaggctc cgaatgcaaa acattcaagc ctacctctga
    52561 ctcatcttca cgagagatat agggtggatt ggatacaatt atatcatatt tttcagaaat
    52621 ttctgcaaaa caatcagatt ttttaaaaaa tatattaaga ttttgatcgc tagcattctc
    52681 tgatgcaagc tctaaggcct cttgagaaac atctgctgct gtcactgacc aatctggtct
    52741 attttttgct agagcgagag caatagctcc actacctgtt ccaatatcca gaactgagag
    52801 attcgtctca agattttcag ttagaataag ctccactaac tcctctgttt ctggacgagg
    52861 aatcaaaacc cgttcatcca cctttaaatg cattccataa aaatctgcct gtccaatgat
    52921 gtactgagct ggcttgtgag ctgctagttg ctggtaaata tcttctacaa attgtttttc
    52981 ttcctctgtt gtcacctcct gctggagggc aaaaataaag tctgtaaaag atagattttt
    53041 cagactacga tagacaaaag agaggctttc cgcttcctct ccttgtctta tcaactcttc
    53101 ttcaaaattt gaaaataatt gagctaattt cattatttgt ttaattcttc tagtttttgt
    53161 gtttggtcat aaagcaccaa ggcatccaca acttcgtcca atttaccaga caaaatcgta
    53221 tctagttttt ggagggtcaa gccgatacgg tggtctgtga cacggttttg tgggaagtta
    53281 taagttcgga tccgttctga acggtcacca gtaccgattg tcgacttacg ctcagcgtct
    53341 tgttcatcct gagcaatctg agcaaagtgg tcagcgacgc gtgcacggat aatcttcata
    53401 gccttctcgc ggttcttctg ctgggtacgt tcttcctgca tctcaacctt gatattggtt
    53461 ggcaagtgaa cgatacgaac ggcagtcgca accttattga cgttctgtcc accagcacca
    53521 gaggcgtgat agatgtcgac acgaaggtct tttggatcaa tgtcgtattc aacctcttca
    53581 acttctggca taacaagaac tgtcgctgtc gaagtatgaa cacggccttg gctttctgtc
    53641 acaggaacac gttgcacacg gtgggcacct gattcatact taagcttaga gtatacagac
    53701 tgacctgaaa ccatagcaac cacttcttta aaaccaccga caccattcat agaggcttcc
    53761 atgacttcaa agcgccaacc ttgggcttcc gcatactttt ggtacatagt tagcaaatct
    53821 ccagcgaaaa gtgccgcttc gtctccacca gctgctccac ggatttcaag gatgatattc
    53881 ttgtcatcgt ttggatcctt tggaaggagc aaaattttca gtttttcttc atattcttct
    53941 ttttcagcct tggcatcttt gagttcttgc ttggccaatt cttccaagtc cgcatctccg
    54001 cctgattcct taatcatctc ttcggcatcg acgatatttt gaaggacttg tttatactca
    54061 cggtaggcta ttacggtgtc acgattggaa gcttcttctt ttgaaagctc cataaaacgc
    54121 ttggtgtctg aaacgacatc agggtcactc agcaattctc ctagttcttc ataacggtct
    54181 tctacagctt gtagttgatc atagatgttc atttttcttc attctcctta ttgatttcag
    54241 gggcaaaata atgtttacgg caaaccgaga tataggtttc attaccacca atctggatct
    54301 gttctccatc gtaaacgggc agtccatcct gtgttcgcaa caccatggtc gcctttttct
    54361 tgcaatactg acagatggtc ttgatttcgt caatcttgtc cgctaaaagc aagagatatt
    54421 tggaaccttc gaacaattca ttgcgaaagt catttttcaa gccaaaagcc atgacgggta
    54481 tgtctaactc gtccacaaca cgagctaggt cataaacatg gtggcgtttg agaaactggg
    54541 cttcatcgac caaaacacag taaggttttt ctggtaggtc tcggatatag ccaaagatat
    54601 ccgttgtttc ctcaatcgca agggcagggc gtttcatgcc aattcgactc gacacatagc
    54661 caacaccgtc acgcgtatcc agagccgagg tcataatgac aacacctttt ccttgctcct
    54721 cgtagttata ggccactttg agaatctcaa tcgttttacc agagttcatg gtcccataac
    54781 gatagtacaa ctgtgccatg tttcttgctt cacgtccatt tctaaatttt tgctacattc
    54841 tagtatatca taattttctt aagctttaaa cggcaaaatg tggtaaaata gaagaaatca
    54901 aaaactagtg gaggaagcta ttatgccatt tgtacgcatc gatttatttg aaggacgcac
    54961 gctcgagcaa aagaaagctc ttgctaagga agtaacggaa gcggttgttc gcaacactgg
    55021 agcacctcaa tctgctgtcc atgtcatcat caacgacatg ccagaaggaa cttacttccc
    55081 acaaggggaa atgcgtacca aataagctag cttaagcaga attgcttagg ctttttcaat
    55141 ctccaagtag cattcattga agaaatatcc taaatttgtt acaatttgaa aagaaacttg
    55201 gagaatttcc aagaaaagag caattaatta aaggaaacat tatgattaca cgtgaatttg
    55261 ataccatcgc tgctatatct actccactag gtgaaggggc tattggtatt gtccgcctga
    55321 gcggaacaga cagttttgct attgcgcaaa agatttttaa aggaaaagac ttgaacaagg
    55381 ttgccagcca cactctcaac tacggtcaca ttatcgatcc tctgactggt aaagtcatgg
    55441 acgaggttat ggttggggct atgaagtctc caaagacctt cactcgtgag gatattatcg
    55501 agattaacac ccacggtggg attgcggtga ccaatgagat tctccagcta gctatccgtg
    55561 agggagctcg gttggcagaa cctggtgaat ttaccaaacg tgccttttta aacggtcgcg
    55621 tagatttgac acaggccgag gcggtgatgg atatcatccg cgccaagaca gacaaggcca
    55681 tgaacattgc agttaagcaa ttagacggct ccctttctga cctcattaac aatacccgtc
    55741 aagaaatcct caatacactt gcccaagttg aggtcaatat cgattatcct gaatatgatg
    55801 atgttgagga agctactact gccgttgtcc gtgagaagac tatggagttt gagcaattgc
    55861 taaccaagct ccttaggaca gcccgtcgtg gtaaaatcct tcgtgaagga atttcaacgg
    55921 ctatcattgg acgtcccaac gttgggaaat caagccttct caacaacctc ttgcgtgagg
    55981 acaaggctat cgtaacagat atcgctggga caacacgaga tgtcatcgaa gagtacgtca
    56041 acatcaatgg tgtacctctc aaattgattg atacagccgg tattcgtgaa acagatgaca
    56101 tagtggaaca aatcggtgtt gagcgttcga aaaaagccct caaggaagcc gacttggttc
    56161 tactagtgct aaatgccagt gaaccactga ctgcgcaaga cagacaactt cttgaaatta
    56221 gccaagatac caatcgcatt attctactta ataaaaccga cctgccagaa acgattgaaa
    56281 cttcgaaact acctgaagac gttatccgta tttcagtcct taaaaaccaa aacatcgaca
    56341 agattgaaga gcgaatcaac aacctcttct ttgaaaatgc tggcttggtc gagcaagatg
    56401 ctacttactt gtcaaacgcc cgtcacattt ccctgattga aaaagcagtt gaaagcctac
    56461 aagccgttaa tcaaggtctt gagctgggga tgccagttga tttgcttcaa gttgacttga
    56521 ctcgtacttg ggaaatcctc ggagaaatca ctggggatgc tgctccagat gaactcatca
    56581 cccaactctt tagccaattc tgtttaggaa aataagaaaa atccatgatc cttcattcgg
    56641 tcatggattt tattgtcttt attagtaatc tggtcttaag acccctgtta cagttgcctt
    56701 agttgcttcg tagtcgccat ctacgacaac cttgataatg cgtttggcat cttcttctgg
    56761 tgctggaaca agaggtagac gagtgggtcc agcttcaaat cccatatagt taagaactgc
    56821 cttaactgga gcaggacttg gataagagaa gagagcatta accttaggaa tgaatttacg
    56881 ctgaattgct gcggctttct tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat
    56941 ttcatcccca tttgtatgag aggcaacaga aataacccca tccgccccaa ggttcatggc
    57001 atggaaagca tctccatcct cacctgtata aatcaagaac tcttcaggct tgtgctcaat
    57061 caagtaagcc atattagcca agctagtaca ttctttgaca ccgataatat ttggatggtc
    57121 agccaaacga agcatggttt ctggagtcaa ttcgacaact acacgccctg gaatgttata
    57181 gataataatt ggtaggtcag aagcatctgc aatagcctta aagtgctgat acatcccttc
    57241 ttgagaaggt ttgttgtagt aaggaacaat agcaagccca gctgcgaaac caccaaattc
    57301 cgctacttct ttgacaaact caatagagtc acgcgtatca ttagtaccta cacccgcaat
    57361 caaaggaacg cgtccattga caaccttttg tacagccgca aacaactcca actcctcatc
    57421 gtgggtcaaa gttggactct cagcagtcgt tcctgcgaga agaattccat ccgtatgatg
    57481 ggccaataaa tgctcaatca aggctggaat agcatcaaag ttaatggaac catcctcatg
    57541 gaagggggta ataaaggctg taatgatttt acattctttt aaatcttgat aagacacgaa
    57601 aacacctctc tatttcaaag aaggagttca tctgaactcc taaacgatat gactatttta
    57661 attcaaattt caattcggct gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa
    57721 tctgaactga gttccaagca gcacctttga gaaggttatc tgaaacaacc cacatgtgaa
    57781 ttcctttttc tgcatccatg tctttacgga tacgaccaac aaaggtatca cgcgaaccaa
    57841 ctgcattgat agcttgagga tagatttgat gagctacatc atcttcaaga acagcacctg
    57901 ggaaggctgc gatagctgct tttacttctt cgattggagc cacttctttt gtttcgatat
    57961 aaacagactc agagtgagct gacaagactg gaatacgcac acatgttgca gatactgcaa
    58021 tgctatcatc ttccataatt ttcttagttt ccttggtcat cttcatctct tcgtacgtgt
    58081 aatcattatc agtgaaaaca tcaatttgtg gaagagcgtt aaaggcgata ggataatgtt
    58141 tcttgtcacc acctgaaggc aagatttccg catgcaaatc acgtggtttc acaccatcat
    58201 tcaagacttc acgaagttca cgttgtgtct caagaattgc tcccatacca gcacctgaaa
    58261 cggcttgata agttgaaaca atgatacggt ccaagcccca tttttggcga accggctcaa
    58321 gagccaccat catttggatt gttgaacaat tagggcaggc aatgattccg ttgtgagcat
    58381 caagtgcatg agcattgacc tctggaacaa ccaaaggaac atctggattt tgacggaaat
    58441 aagatgtatt atctactact accacgccag cttttactgc gtatggtgca tacttagctg
    58501 atgtagaact acctgctgaa aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg
    58561 tttcttcaat tgtaatatct tgatctttaa atttcaatga cttacctgct gaacgtgcag
    58621 aagcaaggta acggatttta tcgattggaa gtgttgattc ttccaacatt tttatcatct
    58681 gagcaccgac agcacctgtc gcgccgacta cagcaactgt atatcccata aataacctct
    58741 ttcggaattt tctaaaaatt tctataatag aagtattata ctactttttc catgaattgc
    58801 aaagcttttt cattattttt tggaaaataa aaatcccagt cgctagacta gggactaaga
    58861 ggcatcttca tgtgatgagc aggttcacac aactcatcaa ggtccgctcc tgcgttatga
    58921 cctccttatg ctcaatagta gtccgaagac tacctatcga ctcatcgcat attctatatt
    58981 actagagata cttgattttg tcaataagaa attttttcga tcgagtataa caaaaaactc
    59041 ttgtattcaa gagtttccct atacatatca tgctaattgc cgggattgaa ccggcgacct
    59101 catccttacc atggatgcgc tctgccaact gagctaaatc agcttactta agaagtatac
    59161 tataatcaga aaaacttgtc aagtttcctt agaaattttc cataggaaaa agccaggtaa
    59221 gaactaccta gcttatcttc ttctatttac ttaaatcaat tcgacgacca attttaccaa
    59281 taataatcgc tccaataatc aatgaagcaa attcaccgat tcctgttgta aaccaagtaa
    59341 ggaagaatgg taattctgct acaatattta actctgcagc gatagtaaac atggaaattg
    59401 aaaagaggat tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct
    59461 tgctatattt tgcaaaaagc caaacaccta aactgaggaa tactaaggtt gaaccaccac
    59521 caacaaagac atctagcagt ccgaagctaa agaaattagc aatcatacaa ccgatggtaa
    59581 ctccgatgat gtacttagga ttgtaaaaag ccataaagtt catcatttct gaaatacgaa
    59641 actgataagc accatagctg atggcattta ggggcggtgt gacagtcaaa acgacgtaga
    59701 tagcagcgac gattgcaata tctgcaacat cacgaatagt taattttttc atcttttctc
    59761 ctttggcggt tatccgcgtg taatatgctt ggtgaaagaa gctaagcacc aagggttgat
    59821 tcattcaacc ttactagtat agcacaatag cctgctttat gctatactta aagcatgaaa
    59881 aaacctattc aaaaattttt taacaatgaa atcttagcct atctcttttt tggccttgcg
    59941 acaactctag tttcgattct ctcacgacta gtcatttatc aactaagtca tcaggaactc
    60001 cttgctacgg ccttggcaaa tattatcggt atcttatttg cctttatcac aaatgatacg
    60061 attgtattta agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt ttctcttgct
    60121 cgcctttcta cttttctgtt agacttgttt ttaacttttc tctttgtaac ccaatttcct
    60181 cacatcatag ggcaattcgt aactgaaaac attgataaga taaatgctat tgaaacaata
    60241 attgcacaaa tattcattat tatcatcaat tatatcttga gcaaggtcta tatttttaga
    60301 aaataatgct ccatttatga gccttttaat tgccttctat aatgatttag gatacaatga
    60361 aacacgaaac attgaaagga aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga
    60421 ggaaatgtta ttgaccttgc tgtcggtgtt gtcattgcct ctgcttttgg tgctatcgtt
    60481 acttcacttg taaacgacat tatcactcct cttattttaa atcccgcttt gaaagctgct
    60541 aaagtcgaac gtatcgctca actttcttgg catggagtcg gctatggtaa ctttttaagt
    60601 gctattatca attttatctt tgtaggtacc gccctcttct ttattatcaa gggcattgaa
    60661 aaagcacaga aactgactgg cataaagaaa gaaaaaactg ccgaaaaaaa accaaccgaa
    60721 ttggaagtcc ttcaagaaat aaaagctctc cttgagaaaa aataatcgat taaaaggatc
    60781 tagcgcaaag ctaaatcctt ttttctttac tctttgggta acttgcctgc tttttcaagc
    60841 atttttttga taagataagg catcttaata ttctcccgcc cttttttctc aatcagtttt
    60901 ttcacaaatt ctggcatttg taaatcttca gattcagcta aaatgttttt cgtctcgtct
    60961 gaaggaacta actcatcaaa ggtctcttct tctgggagaa attccttaaa ctcttgattt
    61021 tcattgactc taactgtatt gaccaaagca tcaatcaaac gagaatctgt atttggcatt
    61081 ggtggacgat ggtagtttac cccaaattcc tgacataaat cataacattc cacatcattg
    61141 tcaaacaaga cctcaatatg ctcactgatg aaactaatag gtacaaaaat ataatggtct
    61201 ggatgttctg tctgttctct gagatactcc aaaacatctg gtttaatcca tggaatacca
    61261 atatcactct cactctgcca agtgttggta tattgttctg aactcaagcc cagtttttca
    61321 gcgactagct tgctattttc gaaaatttgg tctatataag gatctccaaa gtccaaggca
    61381 aaaataggca cactatgggc tgaaaagatg actttaaagc tgtcttgctt tacttcttct
    61441 tttaaaatct tagcaatttc atctgcccaa tagtttaaga gcgcttcttc ctgataccag
    61501 tccttaatga ccaaaaattg aatttgtttg ctttctaaaa atttttcata gcccatgaca
    61561 gagtagaaag aataatgggg ctccaaaatc aagcaaatac actgttcaat tccgtctgct
    61621 tccatttgac cgatcacatc tggaataaag ggactggaaa acttattagc aaagtagaca
    61681 ctgtattcat tccccagcct agcttctacc aaggcaacct cttgacgggt aattttttgc
    61741 agaggcgtgc ctccaattcg tacataatta tcatagagag tctgaatctc gtggtcttgg
    61801 ggtctcatcc cacgacgaat atttgtgaaa aaatcagcta caccttcaaa ggtaatctct
    61861 tctggtgaac cgaaggtcat cattaaaatt gcttttttca tgactgcttc cttgtgatgt
    61921 ttttatcaag tttattttat cattaattca tcgataagta aacgctagca tagggacatt
    61981 ctcaatcttc tgtcttttgt ttttctcttc tttctatgat acaatggaaa aaataaattc
    62041 aaaaggagtt ttttatgact tatccaaatc tcttggaccg cttcttaacc tacgttaagg
    62101 tcaacacgcg ctctgatgaa cactctacta ctactccaag tacacagagt caggttgact
    62161 tcgcaacaaa tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat gtttactatc
    62221 taccgaatgg ttttgctatt ggaaccttgc cagccaacga tccgtcttta acacgtaaga
    62281 ttggttttat atcgcacatg gatactgctg attttaatgc tgaaggagtc aatccacagg
    62341 taattgaaaa ctacgatggt ggtgtgattg aactagggaa ttctggtttc aaactcgatc
    62401 cagctgactt caagagtctt gaaaaatatc caggacaaac gctcatcaca acagatggaa
    62461 caagcttgct aggcgctgat gacaaatcag gaattgctga aattatgaca gccattgaat
    62521 atctaactgc tcatcctgaa attaagcact gtgagattcg tgttggtttt ggtccagatg
    62581 aagaaatcgg tgttggtgcc aataaatttg atgcagaaga ttttgatgtg gattttgcct
    62641 acactgttga tggtggtcca ctaggtgaac ttcagtacga gactttctca gccgctggtg
    62701 ctgaattgca tttccaaggc cgtaatgtcc accctggtac tgccaaaggg cagatggtca
    62761 atgcccttca gctagcaatt gattttcata atcaacttcc agaaaatgac cgacctgagt
    62821 taactgaagg ttaccaaggt ttttaccatc taatggatgt gacaggtagt gttgaggagg
    62881 cgcgtgcaag ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg cgtaaagcat
    62941 ccatgcaatc tatcgctgat aagatgaatg aagaacttgg gagcgaccgt gtcactctca
    63001 acttgacaga ccagtactac aatatgaaag aagtcattga aaaagatatg actccaatta
    63061 ccattgctaa agccgttatg gaagatctag gtatcacgcc tattatcgaa ccaatccggg
    63121 gtggaacaga cggctctaag atttccttta tgggaatccc aactccgaat atctttgcag
    63181 gtggcgaaaa tatgcacgga cgttttgaat acgttagcct tcagactatg gaacgtgcag
    63241 ttgataccat cattggcatc gtagcttata aaggctaaaa agacgaggta gctcagctac
    63301 ttcgcctttc tttttattct actggttttt cttgatttcc agtagttgta gaagattctg
    63361 ttgttttatt ttctgaagtt gattcagcag gtttagaatc tcttgtattg cttggtttgt
    63421 tttcgtcgct agcagtttca atgttagatt ctgcagttgc gtttggttgg ttctcagcac
    63481 tggtgttatc accatttgct tcagcatttc ttgctggact tgtttcttca cttgcgctag
    63541 cttttgactg gatttgatga ttcaaaacta gaatagcttt tgtcgattca agtaaagctg
    63601 ttttgtcttt actattagca gaaagttgat ctaataatgc atccacctta tcaaaagtcc
    63661 gcatcagatc cattattact ttctaaataa aagtgaagcg acatgagaat atcgtagagt
    63721 ttttgataga gtacaagtgt ctgaggatct tgctcagcat tttccttttc ttgttgaagg
    63781 gcgctagcga tacgagtcaa gacatctttt acctgactgt ttacttcatc caagtctgca
    63841 tcagccttgt ttgtggcagc ttttagattt tctacttctt ctgccaaaga ttgtctgatt
    63901 ccttcttcat ggattcgttc caagagttga tttgccttgc tcaaaagact ttctacttct
    63961 tccttgctat ctgtcgcaga ttattggttg ctatctacca tgtactccta aaacaggaga
    64021 gttataatcc aagattacaa ggccttacag aaataagaaa tccagataag acaatgttcg
    64081 tccaagacgc tattcgcttc gcacagcagc acggattcaa tatgctttaa ttttaaagtt
    64141 taggtgtcaa gacctctttt tagtgtgccc aaaatttaga gaagtaatca atcaactaac
    64201 ttttattttt ttcaaacttt cagtaaactg acctaaagct aactcaatct gtctttgttc
    64261 gataggcttg tctttgtaga tgcttctgct atcagctaga agttgatcta cttttgccaa
    64321 gactgccttc tcatcaaaag ttccaggttg atagttggat tgcagggatg gaatcttgtt
    64381 tttcaaagcc gcttcatatc ccttagtttg aaccttgatg tagtgattgt ggtcgccacg
    64441 aggaatcaca aaaccttctg aatcttcact tataattcga ttggcatcaa aaccatgacc
    64501 atcttcttcc tcatggtgga catgtagtga cggattactt aatacagaac tagaagaact
    64561 tcctacctct tccgtgttag agtgtgatgg gggattgtta agagatgact taggaatata
    64621 gtgatagtga ccccatgtct tactatataa gcatcacctg tatctctgac aatatcatta
    64681 gggttaaaga cataaccatc atctgctgca gaaacaccat tattcggtgt caccgacaaa
    64741 gattgactga gagctgtagt attctctgat aattatactt ttgcagctgc taattcacct
    64801 gccgacaagt cactctcagg aatgaaatga tagtgaccac catgtggtac tatagtagat
    64861 tgaaatagaa tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta
    64921 gaaactatga tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata
    64981 acgtccctgt aattttacta cagatacttc tgcactagct cctttatcgt ctttaccatg
    65041 ttcttgtttt tggcgattga tttcatcttt tattcgtaca ttttctgcat gagcttgatc
    65101 tttaaggtaa acataatact ttccatctac cttaataata tatcctccct taacctaact
    65161 gacgatatct tgatctttcg gctgatagtt gggggctttc attaatagct cttcactaaa
    65221 gagcgcatcc aaaggaactt taccattata gcagtgataa tgatcgccat gagaagttac
    65281 ataaccttga tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact
    65341 aacctagtct ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga
    65401 aacacgattt ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag
    65461 acttaaggaa aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat
    65521 tacctcattt ctataattat ttatatgatg tcttcattat taaatgatta aataaattaa
    65581 ttaaccaatt aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt
    65641 ttatatatta ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga
    65701 gagaacttca tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga
    65761 taaattcttt tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt
    65821 gaatataaca ctatctaaac ctaatccgta actagctgta aatttttcta atttttcttg
    65881 tacaggatct actgctggag cttcctctaa tgctggatct aacatagggt cactccccac
    65941 attcccttct ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc
    66001 gtttggtgcc tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt
    66061 tccagtagat acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc
    66121 tcctgtaaaa tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat
    66181 tgttccgtcc atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt
    66241 tgctactttt tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt
    66301 actattccca gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc
    66361 taccttttca tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat
    66421 acttggttta tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga
    66481 ttgattgtcc aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct
    66541 ggttgttcct tggtttaatt tcggaatcgg taatttaatt tcaccaactt tatagttatt
    66601 ttctaaataa gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt
    66661 aggcactgca aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa
    66721 aatcgtttga ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata
    66781 acttacttct ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata
    66841 aggttgatct aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga
    66901 tactttctcc aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa
    66961 ttttttctcc aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt
    67021 aaagttttga ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc
    67081 tccagtataa actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc
    67141 atagttactg tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg
    67201 atggtgatct ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc
    67261 acgtttgaca ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa
    67321 atctttcatt tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa
    67381 tccattatga ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc
    67441 tgtcaagtcc ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga
    67501 ttcatcttca gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc
    67561 atgtgaagtt cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg
    67621 aagagtcggt tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct
    67681 tacaatataa gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc
    67741 agatgctgaa gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc
    67801 tagactagac actacttcat taggttttgc atttgtagaa actgtagaac cagttccact
    67861 gataggcacc attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa
    67921 gtggtaatgg tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc
    67981 agggtcaaag accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag
    68041 ttccttcaaa agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt
    68101 tgctacagat tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg
    68161 catatttttt ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct
    68221 tttgggaatg tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc
    68281 gataatatca gctagattaa agacataacc atcatttgtc gtatatcgtc cctgagacct
    68341 tgctacagca acattagagt taaccttctc attatctttg acatgttctt gtttttgacg
    68401 attgatttca tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata
    68461 atattttcca tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc
    68521 tttaagttga tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg
    68581 aactttccca ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt
    68641 aattttgatt acaatttgct cagcctgaat tccttctttc tggctaacct ggtctggtgt
    68701 caagttttca cttttctgac ttgactggct gccatccaca taagagacac gattattgtc
    68761 cttattttcc tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat
    68821 aacagctgat ccagctgcta tatatttttt actaaatttc ataaatccct catttcaata
    68881 aatgatgaag ttttttctca acttctttta ctttattaaa tagttttcta aaccggttat
    68941 ttaaccattt aattaaccag taaatagttt actatttaaa attacttttg tcaagtttct
    69001 gttacgtttt tctaaaaaag agaagtaaca cgaaaggtta cttctccata aaatatgctc
    69061 cattcatttt actactgtat cggagccggt tgactttttt ttaacaaagc caagagacta
    69121 tctacttctg ctgaaatagt gttattatct ttcgttccga gaagaagact actttttaga
    69181 ccagtcaatg tctccatagc attttgtcta atactagaat ctgttacttt ttctagcaag
    69241 gcctccgcct ctgctatctt agcgttaatc acagaatgct ctacttgagg aatttcagtc
    69301 tcatctgtag tatcttcagc ttcttcctct gtctcttccg tatcagtgct tggtttataa
    69361 agattatctg ctgaaggatt taaaccagcg tgattctctt tttcatcaga ttcagggtga
    69421 gttggctcac ttacttcatc atgtccctta tcttcatcag gtttactgtc ttggtctgcc
    69481 ttatttttac gaacatggtc
//
LOCUS       DBERAE010000005        68908 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.05, whole genome shotgun sequence.
ACCESSION   DBERAE010000005 DBERAE010000000
VERSION     DBERAE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 68908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.05"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..297)
                     /locus_tag="ACL70N_000417"
     CDS             complement(1..297)
                     /locus_tag="ACL70N_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589288.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACL70N_000418"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACL70N_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGS0589289.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3571..4797)
                     /locus_tag="ACL70N_000419"
     CDS             complement(3571..4797)
                     /locus_tag="ACL70N_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGS0589290.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAASRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="ACL70N_000420"
     CDS             complement(4840..5532)
                     /locus_tag="ACL70N_000420"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS0589291.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="ACL70N_000421"
     CDS             complement(5705..7456)
                     /locus_tag="ACL70N_000421"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589292.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATMVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGV
                     TYHKMYSLQAGAMADTL"
     gene            complement(7446..9191)
                     /locus_tag="ACL70N_000422"
     CDS             complement(7446..9191)
                     /locus_tag="ACL70N_000422"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589293.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9397..9693)
                     /locus_tag="ACL70N_000423"
     CDS             complement(9397..9693)
                     /locus_tag="ACL70N_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGS0589294.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9846..10303)
                     /locus_tag="ACL70N_000424"
                     /pseudo
     CDS             complement(9846..10303)
                     /locus_tag="ACL70N_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10437..11264
                     /locus_tag="ACL70N_000425"
     CDS             10437..11264
                     /locus_tag="ACL70N_000425"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGS0589295.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11276..11413
                     /locus_tag="ACL70N_000426"
     CDS             11276..11413
                     /locus_tag="ACL70N_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0589296.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLLKSV
                     N"
     gene            11524..11652
                     /locus_tag="ACL70N_000427"
     CDS             11524..11652
                     /locus_tag="ACL70N_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HGS0589297.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12035..12130
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12530..13111
                     /locus_tag="ACL70N_000428"
     CDS             12530..13111
                     /locus_tag="ACL70N_000428"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGS0589298.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13111..14373
                     /locus_tag="ACL70N_000429"
     CDS             13111..14373
                     /locus_tag="ACL70N_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGS0589299.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTRFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14424..14885)
                     /locus_tag="ACL70N_000430"
     CDS             complement(14424..14885)
                     /locus_tag="ACL70N_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGS0589300.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14882..15646)
                     /locus_tag="ACL70N_000431"
     CDS             complement(14882..15646)
                     /locus_tag="ACL70N_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGS0589301.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15827..16231)
                     /locus_tag="ACL70N_000432"
     CDS             complement(15827..16231)
                     /locus_tag="ACL70N_000432"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGS0589302.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16301..17782)
                     /locus_tag="ACL70N_000433"
     CDS             complement(16301..17782)
                     /locus_tag="ACL70N_000433"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS0589303.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17801..18979)
                     /locus_tag="ACL70N_000434"
     CDS             complement(17801..18979)
                     /locus_tag="ACL70N_000434"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGS0589304.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19144..20151
                     /gene="galR"
                     /locus_tag="ACL70N_000435"
     CDS             19144..20151
                     /gene="galR"
                     /locus_tag="ACL70N_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGS0589305.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20197..21234)
                     /locus_tag="ACL70N_000436"
     CDS             complement(20197..21234)
                     /locus_tag="ACL70N_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGS0589306.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21235..21588)
                     /gene="nmlR"
                     /locus_tag="ACL70N_000437"
     CDS             complement(21235..21588)
                     /gene="nmlR"
                     /locus_tag="ACL70N_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGS0589307.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21832..22722)
                     /gene="czcD"
                     /locus_tag="ACL70N_000438"
     CDS             complement(21832..22722)
                     /gene="czcD"
                     /locus_tag="ACL70N_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGS0589308.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22855..23391
                     /gene="sczA"
                     /locus_tag="ACL70N_000439"
     CDS             22855..23391
                     /gene="sczA"
                     /locus_tag="ACL70N_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGS0589309.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23557..24363)
                     /gene="pnuC"
                     /locus_tag="ACL70N_000440"
     CDS             complement(23557..24363)
                     /gene="pnuC"
                     /locus_tag="ACL70N_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGS0589310.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24708..26228)
                     /locus_tag="ACL70N_000441"
     CDS             complement(24708..26228)
                     /locus_tag="ACL70N_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGS0589311.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLNGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(26221..26949)
                     /locus_tag="ACL70N_000442"
     CDS             complement(26221..26949)
                     /locus_tag="ACL70N_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589312.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(26964..27728)
                     /locus_tag="ACL70N_000443"
     CDS             complement(26964..27728)
                     /locus_tag="ACL70N_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGS0589313.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27732..28175)
                     /locus_tag="ACL70N_000444"
     CDS             complement(27732..28175)
                     /locus_tag="ACL70N_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS0589314.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28857..29153)
                     /locus_tag="ACL70N_000445"
     CDS             complement(28857..29153)
                     /locus_tag="ACL70N_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS0589315.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29175..30239)
                     /gene="pepA"
                     /locus_tag="ACL70N_000446"
     CDS             complement(29175..30239)
                     /gene="pepA"
                     /locus_tag="ACL70N_000446"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGS0589316.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPYVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30640..31341
                     /locus_tag="ACL70N_000447"
     CDS             30640..31341
                     /locus_tag="ACL70N_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGS0589317.1"
                     /translation="MTKTILVTGGTSYISSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31357..31467
                     /locus_tag="ACL70N_000448"
     CDS             31357..31467
                     /locus_tag="ACL70N_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGS0589318.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            31764..32723
                     /locus_tag="ACL70N_000449"
     CDS             31764..32723
                     /locus_tag="ACL70N_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589319.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32713..33669
                     /locus_tag="ACL70N_000450"
     CDS             32713..33669
                     /locus_tag="ACL70N_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGS0589320.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            33666..34418
                     /locus_tag="ACL70N_000451"
     CDS             33666..34418
                     /locus_tag="ACL70N_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589321.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34514..35479
                     /locus_tag="ACL70N_000452"
     CDS             34514..35479
                     /locus_tag="ACL70N_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589322.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35704..35946)
                     /gene="yidD"
                     /locus_tag="ACL70N_000453"
     CDS             complement(35704..35946)
                     /gene="yidD"
                     /locus_tag="ACL70N_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGS0589323.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(35946..36668)
                     /locus_tag="ACL70N_000454"
     CDS             complement(35946..36668)
                     /locus_tag="ACL70N_000454"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0589324.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVVNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36655..37224)
                     /gene="scpB"
                     /locus_tag="ACL70N_000455"
     CDS             complement(36655..37224)
                     /gene="scpB"
                     /locus_tag="ACL70N_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGS0589325.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37243..37971)
                     /locus_tag="ACL70N_000456"
     CDS             complement(37243..37971)
                     /locus_tag="ACL70N_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGS0589326.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37971..38705)
                     /gene="xerD"
                     /locus_tag="ACL70N_000457"
     CDS             complement(37971..38705)
                     /gene="xerD"
                     /locus_tag="ACL70N_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGS0589327.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38702..39163)
                     /gene="cbpB"
                     /locus_tag="ACL70N_000458"
     CDS             complement(38702..39163)
                     /gene="cbpB"
                     /locus_tag="ACL70N_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGS0589328.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39160..39681)
                     /locus_tag="ACL70N_000459"
     CDS             complement(39160..39681)
                     /locus_tag="ACL70N_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS0589329.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39657..40628)
                     /locus_tag="ACL70N_000460"
     CDS             complement(39657..40628)
                     /locus_tag="ACL70N_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGS0589330.1"
                     /translation="MTNKIYEYKDDRDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40625..41419)
                     /gene="racE"
                     /locus_tag="ACL70N_000461"
     CDS             complement(40625..41419)
                     /gene="racE"
                     /locus_tag="ACL70N_000461"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGS0589331.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41626..41874)
                     /locus_tag="ACL70N_000462"
     CDS             complement(41626..41874)
                     /locus_tag="ACL70N_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGS0589332.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42130..43755)
                     /gene="treC"
                     /locus_tag="ACL70N_000463"
     CDS             complement(42130..43755)
                     /gene="treC"
                     /locus_tag="ACL70N_000463"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGS0589333.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMTDYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43933..45900)
                     /gene="treP"
                     /locus_tag="ACL70N_000464"
     CDS             complement(43933..45900)
                     /gene="treP"
                     /locus_tag="ACL70N_000464"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGS0589334.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATNPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46085..46795
                     /gene="treR"
                     /locus_tag="ACL70N_000465"
     CDS             46085..46795
                     /gene="treR"
                     /locus_tag="ACL70N_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGS0589335.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(46828..47631)
                     /locus_tag="ACL70N_000466"
     CDS             complement(46828..47631)
                     /locus_tag="ACL70N_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589336.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(47644..48537)
                     /locus_tag="ACL70N_000467"
     CDS             complement(47644..48537)
                     /locus_tag="ACL70N_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589337.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(48549..49486)
                     /locus_tag="ACL70N_000468"
                     /pseudo
     CDS             complement(48549..49486)
                     /locus_tag="ACL70N_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(49976..50902)
                     /locus_tag="ACL70N_000469"
     CDS             complement(49976..50902)
                     /locus_tag="ACL70N_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589338.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(50913..51980)
                     /locus_tag="ACL70N_000470"
     CDS             complement(50913..51980)
                     /locus_tag="ACL70N_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589339.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(51989..52915)
                     /gene="oppC"
                     /locus_tag="ACL70N_000471"
     CDS             complement(51989..52915)
                     /gene="oppC"
                     /locus_tag="ACL70N_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGS0589340.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(52915..54411)
                     /locus_tag="ACL70N_000472"
     CDS             complement(52915..54411)
                     /locus_tag="ACL70N_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589341.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(54478..56457)
                     /locus_tag="ACL70N_000473"
     CDS             complement(54478..56457)
                     /locus_tag="ACL70N_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589342.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(57143..58336)
                     /locus_tag="ACL70N_000474"
     CDS             complement(57143..58336)
                     /locus_tag="ACL70N_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS0589343.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(58474..59916)
                     /gene="gtfA"
                     /locus_tag="ACL70N_000475"
     CDS             complement(58474..59916)
                     /gene="gtfA"
                     /locus_tag="ACL70N_000475"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGS0589344.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTMLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(60216..61049)
                     /locus_tag="ACL70N_000476"
     CDS             complement(60216..61049)
                     /locus_tag="ACL70N_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0589345.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(61063..61929)
                     /locus_tag="ACL70N_000477"
     CDS             complement(61063..61929)
                     /locus_tag="ACL70N_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0589346.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(61943..63202)
                     /locus_tag="ACL70N_000478"
     CDS             complement(61943..63202)
                     /locus_tag="ACL70N_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0589347.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(63294..65456)
                     /locus_tag="ACL70N_000479"
     CDS             complement(63294..65456)
                     /locus_tag="ACL70N_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS0589348.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHITLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            65564..66424
                     /locus_tag="ACL70N_000480"
     CDS             65564..66424
                     /locus_tag="ACL70N_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0589349.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            66421..67356
                     /gene="birA"
                     /locus_tag="ACL70N_000481"
     CDS             66421..67356
                     /gene="birA"
                     /locus_tag="ACL70N_000481"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGS0589350.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(67482..67569)
                     /locus_tag="ACL70N_000482"
     tRNA            complement(67482..67569)
                     /locus_tag="ACL70N_000482"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67533..67535),aa:Ser,seq:gct)
     gene            complement(67576..67649)
                     /locus_tag="ACL70N_000483"
     tRNA            complement(67576..67649)
                     /locus_tag="ACL70N_000483"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67613..67615),aa:Ile,seq:gat)
     gene            complement(67685..67755)
                     /locus_tag="ACL70N_000484"
     tRNA            complement(67685..67755)
                     /locus_tag="ACL70N_000484"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67721..67723),aa:Gly,seq:tcc)
     gene            complement(67775..67847)
                     /locus_tag="ACL70N_000485"
     tRNA            complement(67775..67847)
                     /locus_tag="ACL70N_000485"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67812..67814),aa:Phe,seq:gaa)
     gene            complement(67851..67924)
                     /locus_tag="ACL70N_000486"
     tRNA            complement(67851..67924)
                     /locus_tag="ACL70N_000486"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67888..67890),aa:Met,seq:cat)
     gene            complement(67935..68024)
                     /locus_tag="ACL70N_000487"
     tRNA            complement(67935..68024)
                     /locus_tag="ACL70N_000487"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67986..67988),aa:Ser,seq:tga)
     gene            complement(68035..68108)
                     /locus_tag="ACL70N_000488"
     tRNA            complement(68035..68108)
                     /locus_tag="ACL70N_000488"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68072..68074),aa:Ile,seq:cat)
     gene            complement(68122..68195)
                     /locus_tag="ACL70N_000489"
     tRNA            complement(68122..68195)
                     /locus_tag="ACL70N_000489"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68159..68161),aa:Met,seq:cat)
     gene            complement(68201..68274)
                     /locus_tag="ACL70N_000490"
     tRNA            complement(68201..68274)
                     /locus_tag="ACL70N_000490"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68238..68240),aa:Pro,seq:tgg)
     gene            complement(68290..68363)
                     /locus_tag="ACL70N_000491"
     tRNA            complement(68290..68363)
                     /locus_tag="ACL70N_000491"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68327..68329),aa:Arg,seq:acg)
     gene            complement(68373..68458)
                     /locus_tag="ACL70N_000492"
     tRNA            complement(68373..68458)
                     /locus_tag="ACL70N_000492"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68422..68424),aa:Leu,seq:taa)
     gene            complement(68466..68537)
                     /locus_tag="ACL70N_000493"
     tRNA            complement(68466..68537)
                     /locus_tag="ACL70N_000493"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68503..68505),aa:Gly,seq:gcc)
     gene            complement(68560..68632)
                     /locus_tag="ACL70N_000494"
     tRNA            complement(68560..68632)
                     /locus_tag="ACL70N_000494"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68597..68599),aa:Thr,seq:tgt)
     gene            complement(68651..68732)
                     /locus_tag="ACL70N_000495"
     tRNA            complement(68651..68732)
                     /locus_tag="ACL70N_000495"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68696..68698),aa:Leu,seq:tag)
     gene            complement(68738..68810)
                     /locus_tag="ACL70N_000496"
     tRNA            complement(68738..68810)
                     /locus_tag="ACL70N_000496"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68775..68777),aa:Lys,seq:ttt)
     gene            complement(68835..68907)
                     /locus_tag="ACL70N_000497"
     tRNA            complement(68835..68907)
                     /locus_tag="ACL70N_000497"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68872..68874),aa:Asp,seq:gtc)
BASE COUNT        20572 a        15503 c        12731 g        20102 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttaccc ccgaatatac
      841 tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatgctatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac tatcccgatc
     2701 gatttgtcct attcttattt ccttttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttattgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttaccttaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat atttgcgtta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaaa gacgctagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct ataccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 gcaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaagctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaactgca tggaatgaga aggaagtaaa gtcagcgata gaaccagaag gttgtccttt
     4261 ataaatagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactggaata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccactacttc
     4741 agtaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac
     4861 ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt
     4921 atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 ctccgtcatt tgactgataa ttgtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aatccctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tgcggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacgaaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 tttgctatcc aacttgatcc aaatgctcaa gatgagaaag atgggagagg tcagaaccag
     5401 taagaccaag gccaaaaccc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtatcggcc atggcccctg cctgcaaact atacatcttg tgataggtta
     5761 ctcccagagc caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcatct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaagct ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgttgccca gtagagaagc tcgaaccacg ctcggaaaca ggggagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actggtttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgcaagacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatat gagaaacaca
     6421 catgttcaaa acggatattg ccttcttgga ctttggcttg cccattttct tgaagaggtt
     6481 cataggtcct ctcgtctatc agggcaaaga cacgacctgc agaaaccata gccgtttgca
     6541 gagttgaaaa gttttgcgtc acctcaatca aggggtcaaa aaggcggttg atgtactgga
     6601 taaaggcata catggtcccg accgttatcc cgatagaaaa accacggtag ccaaagtagg
     6661 ccatcaagac tgcatagcct agaagtttca gcaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcgtaga ccaagtgttc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaagg cctgaataat cctgattccc tcgatattct
     6841 ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg attttcactg
     6901 acttttttcg atagagattg accaaaagga aaatcaaagg aagaaagagc aagactaaag
     6961 ccgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa
     7201 agagaagatt gcctacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt aacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacgagggg tatgacactt ttaatgacca tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtcaggag tccataaggc ttgagataag acatcaagcg cttcaataca gcccattgtt
     7441 cttgtttatt ctgcatcttc ttctcctttc atttccaact gctgagactg gtaggtttgg
     7501 gcataccagc catccatcgc tagcaagtct tcgtgcgtgc ctcgttcgat aatttgacca
     7561 ttttgtagaa ctaaaataaa atctgcatgg acaacagcac tgaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagtcgcaa agagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatag tacccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag aggaaactca
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaaaccg atggccagaa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg aaccatcaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gtataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgagtta attgccccga tgtgatggca
     9061 tcaatgactc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaatcc cgactagata acggcgtttt tctaacttga aaaaccacca gagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agaaattttc gaagagtaca agaccccagg tttttcttat tcataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtct gtcacaactg gatacttagg attttcatct cccatttgca caacgatgag
     9601 ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttatgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg
     9781 aacattgttg ttgagctatt tgaaagtcaa gatcagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaatttggt tcctttttta tcatggtatg ccttgaaagc
    10201 aaaaaaaaac tgtcacagct aatagaacaa tcccaaagcc aaccatgata ccattttgct
    10261 gaccgatttg gctgagtaca tagtcataag agtagaattt catgtatttt cactcccttt
    10321 cataaaatca ttcttaatta taaacgaaag agagtaattt ttcaaaccat acgttgggga
    10381 aatagatctt tttttggtat aataaaattt ataatctgaa tgaaaaaggt aactttatga
    10441 aacttatctc atggaatatt gattccctaa acgctgccct aactagtgac tcagctcgtg
    10501 ccaaattgtc ccaagaagtc ctacaaacct tggtcgctga aaatgctgat atcattgcta
    10561 tccaagaaac caagctttct gccaaaggac ctacaaagaa acacgtggaa attttagaag
    10621 aactcttccc aggctacgaa aacacgtggc gctcttccca agagcctgcc cgtaaaggct
    10681 atgctggaac catgttcctt tataagaaag aacttacacc cactgtcact ttcccagaaa
    10741 tcggtgcccc ttctaccatg gacttggaag gccgcatcat cactctagaa tttgatgcat
    10801 ttttcgtaac ccaagtttac actccaaacg ctggtgacgg tctcaaacgc ttggaagaac
    10861 gccaagtctg ggatgttaaa tatgctgagt atttggctga actagacaaa gaaaaaccag
    10921 tccttgcgac cggtgactac aacgtagccc acaatgaaat cgaccttgca aatcctgcta
    10981 gcaaccgccg ttcacctgga tttactgacg aagaacgtgc tggatttacc aaccttttgg
    11041 caactggatt tacagacacc ttccgccatg ttcatggcga tgttcctgaa cgctacactt
    11101 ggtgggcaca acgcagcaaa acttctaaaa tcaacaatac aggctggaga atcgactact
    11161 ggctcacaag taaccgtatc gctgacaagg tcactaaatc tgatatgatt gactcaggtg
    11221 ctcgccaaga ccatacaccg attgtcttgg aaattgactt gtaaggattt tctatatgga
    11281 ctacaatgcg gtcattcccg agttgcttgt atcgaatatc gaacagtccc ggtccttcta
    11341 ctgtggttta ctgggtttta ggattgaata ccaacgtcca gaagaaaact ttctcttgaa
    11401 gagtgtcaac taatgttaga ggagggaaca aaggatcaac tagctgaact gacctacccc
    11461 tttggtcgtg gagtcaatct ctcctttggc ataaaggatg ttccaaaact ctattaaaga
    11521 gtgatgaagg caaactatcc tatttatcgt cccttgacca aaagaaagtt tcgtgtcagt
    11581 gatccctata tctatcctca taaatttgca gttttggatc cagatggcta ttttttaaga
    11641 tttagcgagt agaataataa aaattgggaa aagtctttaa agttagaaaa aggcatattg
    11701 tcaggtgtct aaaaacttga tagtatgcct tttatgatgg aaaaatcttc taatactctt
    11761 cgaaaatctc ttcaagccac gtcaacgtcg ccttaccgta ggtatatgat actgactctg
    11821 tcaattctat ccacaacctc aaaacagtgt tttgaggttg tggatagctt cctagtttgc
    11881 tctttgattt tcatttagta taaatgttag cttacaatgg agtttttgtt caccccctct
    11941 tctgtttgtt cgttttttaa atcaaaacac taacaaaata gttgatttat aaagttattt
    12001 agtgtaaaat aaaaacattg gctcaagcct atttaaaatt gaatatcgtt ttacttgttt
    12061 atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa cacctaacaa taagtaagtc
    12121 agcagtgaga tatggtcgtt tttgccatgc ctatttgggg gacttactta gagattaagt
    12181 aggtcctttt tgaatatttt taatatttcc cttaattagt gcggacggga ggtgaaatta
    12241 tcctgtgaat aatttcagga attcagggaa tttcatccct aatttttgag cccctagctc
    12301 tttcatttct aggcttaggc taaaatagtt ccccgaacta ttttactctc aaaaatcccg
    12361 tcatagacaa taacaagatt attgtctatg ataccactac atcgggaaat atttgataag
    12421 actattacga gcgaagcgag tcttatcaaa tatatagtat tagcaaaagg gatcactata
    12481 gaaacatttc aacaacaagt aaattagctt ttagacttta ggaggtctta tgaaattatt
    12541 agaagatcgc atcctcaagg atgggcatat cttgggtgat aacatcctca aggtagattc
    12601 ctttttaacc caccaagttg actttagctt gatgcgagag attggtaagg tttttgcgga
    12661 aaaatttgct gctgccggca ttaccaaggt cgtaaccatt gaagcgtcgg gtattgcccc
    12721 agccgttttt acagctgaag ccttaaacgt tcccatgatt ttcgccaaaa aagctaagaa
    12781 catcaccatg aacgaaggca tcttaactgc tcaagtctac tcctttacca agcaggtgac
    12841 cagcactgtt tctatcgctg gaaaattcct ctcaccagag gacaaggttt tgattatcga
    12901 cgatttcctt gctaatggcc aagctgctaa aggcttgatt caaatcatcg aacaggccgg
    12961 tgccacagtc caagctatcg gtatcgtgat tgagaaatcc ttccaagatg gtcgtgattt
    13021 gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgc ttggatcgtt ttgaaaatgg
    13081 tcaggtcgta tttaaggagg cagatctcta atgcaaactc aagaaaaaca ctcgcaagca
    13141 gccgttctgg gcttgcagca cttactagcc atgtactcag gatctatcct ggttcccatc
    13201 atgattgcga cagcccttgg ctattcagct gagcagttga cctacctgat ttctacagat
    13261 atcttcatgt gtggggtggc aaccttcctc caactccaac tcaacaaata ctttgggatt
    13321 ggactcccag tcgttcttgg agttgcattc cagtcggtcg ctcccttgat tatgattggg
    13381 caaagccatg gtagtggcgc tatgtttggt gcccttatcg catctgggat ttacgtggtt
    13441 cttgtttcag gcatcttctc aaaagtagcc aatctcttcc catctatcgt aacaggatct
    13501 gttattacca cgattggttt aaccttgatc cctgtcgcta ttggaaatat gggaaataac
    13561 gttccagagc caactggtca aagtctcttg cttgcagcta ttactgttct gattatcctc
    13621 ttgatcaaca tctttaccaa aggatttatc aagtctatct ctattttgat tggtctggtt
    13681 gttggaactg ccattgctgc tactatgggc ttggtggact tctctcctgt tgcggtagct
    13741 ccacttgtcc atgtcccaac tccactctac tttgggatgc caacctttga aatctcatct
    13801 attgtcatga tgtgtattat cgcaacggtg tctatggttg agtcaactgg tgtttatcta
    13861 gccttgtctg atatcacaaa agatccactc gacagcacgc gccttcgcaa cggttaccgc
    13921 gcagaaggtt tggccgtact tctcggagga atctttaaca ccttccctta caccagattt
    13981 tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa aacgcctgcc aatctactac
    14041 gcagctggtt tcctggttct ccttggactg cttcctaagt ttggtgccct tgcccaaatc
    14101 attccaagct ccgtcctcgg cggtgccatg ctggtgatgt ttggttttgt atctattcaa
    14161 gggatgcaaa tcctcgcccg agttgacttt gctaacaatg aacacaactt ccttatcgca
    14221 gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta atctctttgt cagcatgccg
    14281 acagccttcc aaatgttctt ctcaaacgga atcgtcgtag ccagcctact cgccattgtc
    14341 ctcaatgccg tattaaatca taaaaagaaa taagaaaaag aggtgcgagc ctcttttttg
    14401 tgtgacaaaa taaaaacatc tacctattca tatatgctag tgtcatagtc ctgaaaatca
    14461 tctgcatcaa gaacaatttc acaactctta tacttttctc ttacaagtcg ttcggcttca
    14521 tctggatttt cagcctctat acttactaaa cgtgataaag tttctgtaat ttctactgta
    14581 tactttttca gttttagatt gctttccaat aattcaccta ttaacaataa tctatgatag
    14641 gagctatgta gccactctgg caatttatct cctacttccc acccatattt ttccttcatc
    14701 aaagctagtt gtttttcgtc accaaatttc atattttcag ataaccatct cacacaatcg
    14761 ggatctgata aggtacagac gattaaactt aggttatcgt aacggctttc agtttcataa
    14821 tcaggccaga tgacttttaa gaaatcatac acctcttctg atgcaacaag ttgtttcgtt
    14881 ttcataattt ccgatacttt cctctacctt taaattctat tatttctttg tctcttaata
    14941 tttgaagctg ttgcctaatc ttttctttga tatgattgtt cttaacaaag atatttttta
    15001 ggtcactttc aaaacgatac atatcttcaa gggtaaattc tgaaccctct atcttatcta
    15061 tacaatttag aatttctatt gtccaacctc ttgatgacag agagctcttc cttaaaaata
    15121 aaccttgctt aaattctttt gtaacttttt ctggatctct aacttgtcca tcttgcacaa
    15181 gaaatatcct tcctttagaa ggtacttgtg ataaatcaat gttacaacca atccaacctg
    15241 ctcgtctagc agttggtgca agtggttttc tttgaataat cgatttcggt gtaacaaatt
    15301 gcttcggaag gacaagaaag ttatttacct caaaattttt tgtgtaagtt aaaaaaaaga
    15361 aattaggatt attatctgcc tgcacacgct tcatcatcgt tgcataagca ccatcattga
    15421 ttgttgatga aaaatttcct tttttgctct ttagttcaaa ctcctcacta caatgattac
    15481 agtaaaaatc tgctacaggc cgattatttt caaaatgatt taagggattg ttcccacaat
    15541 tagggcaata agactgacga taaacccaat cctccgttaa gatacgtgcc ttttggctat
    15601 tacttttata ggtttctact aattctaaat taaagtgtaa ttccatttaa aaattcctca
    15661 ctaatatgag aactcactcg atataagcaa ttaaaatcta ctataactag tataccacat
    15721 atatgtacct attacatttg tatttcatca ctctctttta tatttccttc taacatatct
    15781 cataaattaa aaatgagtga gataaattta tcccactcac ctttctttat atacttaccc
    15841 gtctttcctc agacctttgg cctgtgacaa acatggtaaa ggttgcttta cagacatttc
    15901 tgccctcttg attggtgata tccacatcca tcacacaggt tgtacgacct tgatggacac
    15961 attctccttt aatggtcaat acatcgtcga gttttcctgc cttaaggtag ttgatagagg
    16021 attggagtgt caccccatca agtcccagcg agataaccac caaaccactg atttggtcac
    16081 atagcgtgaa tagatagcca ccatgggcat tgccatagta gttgagcgac gagttcacta
    16141 ctttggtcgt caccacaacg tgaccatctc tcattttttc aatttcgtaa ttttcaaagg
    16201 cagatatagc gtcaaaatga aagtctttca tcgtttcctc ctgatatttc aaacgacact
    16261 atgatactac tttttatagg actgtgcaag gagaaagctc ctagtctagt aaaattccga
    16321 catgttccac aaagcgcata aaggctgtct gcccttgttc tgtctgcttg tagactcctg
    16381 catcctcaag tacacgcgca aagatagcac ccacagagtc cttgacgatt gcaagggctt
    16441 tttctttatc cgttaggtct ggatgttggg atttgagttg gtctgcccac tcctgatgat
    16501 aatcggcaac tgtaacagct tctcctacaa gatagctcgc gacttgctcc acttcttctt
    16561 tcagacgtgg tggcaagatt gccaagccca tgacctcaat caagccgata ttttccttct
    16621 tgatatgttg gacatccttg tggggatgat agatgccatc aggatgctct gctgaagtct
    16681 gattgtctcg caagaccaag tccaactcaa actgtccatc acgcttacgc gctattggtg
    16741 tgatggtgtg atgcggtgtc ccgtctgtct ctgctaaaat ctgcacacta gaatctgaat
    16801 actgacgcca ttcctggaaa atcttatcag ctaagttaat caaatcctct ttggaatccg
    16861 aagtcaagcg taggacagac attggccact tgataattcc agccttgacc tgctcaaaac
    16921 cagcaaatcg gaaggtcttt tgcaagggag ccaattccat aggaaatacg tgacggcctc
    16981 cctgataatg atcgtgagtt agaatagagc cccccacaat cggcaggtcg gcattagatc
    17041 cagcaaaata tcctggaaac tgctctacga tagccaacag acgttcaaaa ctctgacgac
    17101 taatggccat gggacgatgc tggccatcta aaaagataca atgctcatta aagtaagcat
    17161 agggcgaata ctggaacccc cattcctgac caaccatttc aaaacggata atccggtggt
    17221 tgctgcgagc tgggtggttg acccgaccat ggtaaccctc attctctaaa caaagttgac
    17281 actgaggata attactagct tgcaccaact tggctaccgc aatctctttc ggatcctttt
    17341 caggcttaga gagattgatg gtaatttcaa gttctccata atcagatgga acacgataag
    17401 cgatattttt agcaatggcc ttgagtttga tgtaatcatt tttctgactg agttgataaa
    17461 aatcctctat cgcttgctca ggagagtgga cataggcttc ccagaagtca cgattgacct
    17521 gactcggata aggagtcacc aagtccatca gttcagtacc aaggatttca cgcgcagtct
    17581 gactatcctc aatcatctct aatcgaacgg cttcctcaac tagctggtcc ttgaggtcaa
    17641 tcaatttatc cagattggtc tcaacttcca aaacaccttc tcccactcgt gccaaaacac
    17701 ggttggtcag gtagattcga tccatttcct caaatgaact ttcagaaatg acatgtgtta
    17761 caaatttatc tactaagatc actatagagc ctccttttga ctagtcaagg acgcgagtgc
    17821 cacctgcaac ttcagcgata tagaagcttg gagcgtatcc aactacttcc tcgtagtgtt
    17881 tgcctacagc ttccttaaag gcctcaacag tatctttttg aaccaaggca atggcacagc
    17941 caccaaaacc agcccctgtc atacgagcac cgagaactcc ttcttgtgcc caagctgtgt
    18001 gaacaagagt atccaattcc aaaccagtta cttcataatc atgctccaga gaaacgtgtg
    18061 acgcattcat caaacgacca aatgtttcca aatcacctgc ttgaagggct gcttgagctt
    18121 taagggtacg ttggttttca agcacagcat ggcgagcacg tttcaaacga ttttcatctt
    18181 taatcaaata gctatattgg tcaacggccc actcgtccaa ttcacccagg gtctgaatat
    18241 ccaaggcaac ttgcaattct tccactgctt tttcacactc agcacgacgt tcattgtatt
    18301 tagagtccgc caattcacgg cgtttgttgg tgttcatgat aacaacgaca ttgtccttca
    18361 aatcaagtgg caccaagtcg tattctaaag tattggtatc taagtaaata gcacgttggt
    18421 cagcccccat accaatagca aactggtcca tgataccaga gttgactccg ataaagttgt
    18481 tttctgtttg ttttccgatt ttaaccaaat ccaaacggtc tagttttaaa tcaaagagat
    18541 gctctgccac gactcctgtc aagagctcca aggatgctga agaagacaaa ccagcaccat
    18601 ttgggatatt cccataaaca taaaaatcaa aacctttgtc aatcacgtgc ccagcttctt
    18661 gcaagaaatg aagaacccct tttggataat tggtccagtt gtgctctttt tcaaacttga
    18721 ggtcagcgag aggcacttcg ataatgccct tgtcctcaaa gttagctgag tagaaacgca
    18781 agacttggtc gtcacgctta cgagctgcac cgtaagttcc caaggaaata gcagcaggaa
    18841 aaacgtgccc accgttgtag tctgtgtgtt caccaatcaa attaatacgg cctggtgaaa
    18901 agaaggtttg gtctgcttct tgaccaaaaa cagcaagaaa gtctttgcga aggacttcag
    18961 tagtaagatg ttgtgccata tgaattctcc tttgactgtc cgttaagcca tcttaacgtg
    19021 taatcgtttt ctttctattg tatccaagga atttcccaag gtcaatcctt tttactaaaa
    19081 ttttactaaa atatcagtaa aaagaagaaa aatatgatat actaacctaa tcaaggagga
    19141 tttatggcta ccttaaaaga cattgcacag ctagcctctg tctcaatcgc gaccgtatcc
    19201 cgtgtcctca accgcgacca gagcctatct gttacagaag aaaccagaca ccgtatttta
    19261 accgttgctg aagagctagg ctacaccaaa cacctcaaga caggcgagtc ccacaagccc
    19321 aagcaaaaga ttgccattat ccaatgggtc agcgaacaag gggagctaga cgacctctac
    19381 tactaccaga ttcgcctagg aatagaaaaa agagcccaag agttggacta cgatatcttg
    19441 cgctatttta atgaccatcc ttttacctta agcgaggaag tgattgggat tctctgcatc
    19501 ggaaaattta gccgagctca gatttctgcc tttgaagaat accaaaagcc tcttgtattt
    19561 ctagacagcg atacactttc cctgggacat acctgtatta tcacggattt ttacactgct
    19621 atgaaacagg ttgtcgatta tttcctcagt caagggatgg accgcatcgg gattctaaca
    19681 gggcttgagg aaacaacaga ccaagaagaa atcattcagg acaagcgtct agaaaacttc
    19741 aaaaactaca gtcaagcgag gggaatctat catgatgaac tggtctttca aggaagattt
    19801 actgcccagt ctggctatga cttaatgaag gaggccattc agagcttggg agaccaactt
    19861 ccgccagcat ttttcgcagc cagcgatagt ttagctatcg gtgctctccg tgccctccaa
    19921 gaagctggaa tcagcctgcc agatcgcgtc agcctcattt cattcaacga caccagtctg
    19981 accaaacagg tctatcctcc cctctctagt attacagttt atactgaaga aatggggcga
    20041 gcaggtatgg atattcttaa caaggaagtc ctccacggtc gcaaaattcc tagcctgacc
    20101 atgctgggaa ccagactgac attaagagaa agtaccctaa atcaagaata ggataacata
    20161 aaaaacgaat agagttctaa aactcctatt cgttttttat tcgattacaa tcatagactt
    20221 aatggtctta cgttcatcca tatctttgta ggcttggtcg atatcttcca gtttataact
    20281 tgaagtaaag acgcgacctg gattgatatc accatcaagg acggctttta gtaaaaattg
    20341 cttatcgtat gttgtagcag aagctgcccc acctgctaca gagatatttt gcataaatgt
    20401 cgaaccaaga gcacgattat tatagtgtgg gactcctaca aagcccatac gccctccatt
    20461 atgaagaaca cctagcgcct gttctatagc agcctccgta ccaacacatt caagtgctgc
    20521 gtctgctcct ccaccgagga tttcacgcac cttggtaatt ccttcttgac cacgttctgc
    20581 aacaacagct gtcgcacctg actccatagc catcttttga cggtcttcat gacggctcat
    20641 aaggataatt tgtgatgctc cacgcatctt agccgcgatg acagcacatt gaccaacagc
    20701 cccatcaccg ataacaacaa ccttgtcccc tttttgaaca tttgcaacac gcgccgcatg
    20761 atagcctgtc ggcatgacat ctgcaagagt caaaagggac ttgagcatcc cttctgtata
    20821 gtcagaaggt tgaccaggga ttttaaccag cgcccagttt gcatagtgga agcgaatata
    20881 ttctgcctga aaatcacccc ccaaattatt gccaatatga ttgtcgcaag aaccgtcaaa
    20941 tccagcaaga caggcatcac actcaccaca tccatgtgta aaagggacaa tcacaaaatc
    21001 acctggtttc accgtcgtaa tggcttcccc agcttcttca acaatcccaa tcgcttcgtg
    21061 tccactattt ttgtgtccag ctttcgtttc tggattacgg tacctccata aatctgaacc
    21121 acaaacgcac gcacgaacca cacgaataat cacatcatcc gcttctatta tttgcggacg
    21181 ttcaatgcta gcaagtccaa cctgacctgc ctttgtatat actgctgatt tcatttaaaa
    21241 ttttccttcc ttataaagtt taattttgag atttaaacga tttaaagctg tctgtagctg
    21301 agacaagcgc tcctctaatt tttgcttttc ctcttctaaa ataccaagcc tctcctctct
    21361 cgtttcatct cccttttggt agagcgacat atagtcaact aaactatcta cagagacacc
    21421 cgccgaacga aaacacttaa taaattccag cgcttcgata tcctgatctt gaaaatcacg
    21481 aatcccagta gcagtacgag taatcggtgg cacaagacca acccgttcat aataccgaat
    21541 cgtatccgct gaaattccca acaaatcact ggcagattta atattcacac gctaacctcc
    21601 tctcatttca ttcactgaat tcacgctatt ctaactcact tatcttatta tataactttg
    21661 agttgactcc aagtcaagca ttttgtatct aatcgaaaaa tttttatcat taacaatcat
    21721 atatctggag tttatacaat gctcttctct taccaatttt tgaaatattt aaataataaa
    21781 gaaattactc tattccaaat aagatagtac ccaagtattt ttcacttttt tctaatgttg
    21841 atgctcataa ctccgttcca agtcacacac ctttcgctta tgggtttggt gagtttctag
    21901 gtcagcatca atttcaatgg taatattttg aaaaccacaa tcttttagga aaattcgaat
    21961 agactcttta caagtttcca tatgttccat ttcttttaga caaacatgga caatggcatt
    22021 tttttccaaa gcatccatag tccagagatt aagctgatta aggctggcca cattgtccaa
    22081 tcgctccagg ccactcttta cttgcttgat atcaagacct tctggcacag catccaagaa
    22141 aatcttgagt gtagaccaaa aacgtggaag ggcttttgaa agaataaaga aagaaatgac
    22201 aagggacaaa agaggatcta ggatatacca gtccgtaaat cgaagaacaa tcgccatcag
    22261 gataacagct acccacccta gcgtatcttc cagaaaatgc agactcagaa tagactcatt
    22321 ctttgtcttt cccttaccaa ccaccagact cgctaacaga ttgatagtaa tcgcaataat
    22381 tcctaaccag agaatcccct catcattgac tggttgcgga tgcaaaatct tcgtgacatt
    22441 ttccaaaatg actagaacag agcccgttac gagaatcaca gctgttacca aggctcctag
    22501 caggctaaac cgcttatagc ccaaggtgta ctgattgtct tcttcacgat tggagattgt
    22561 ttctagaaaa gctgatattc caattgcaat cgcatctccc aagtcatgca cagagtcagc
    22621 aagaacagcg ctagaaccaa atactccacc tgcaataaac tcaacaatgg cataagtcaa
    22681 atttaagaaa aaagccaccc aaacagcata ttttgccttc atatttctca ttcctttgtt
    22741 ataatagatt tatgaacacc ttgttcatta tcattatcca ctaaaactca aagaaaggat
    22801 agaagcaaaa cgtcagcttt attcagttct gaacaatttg cctcaagtgt ccatatgact
    22861 aacattgacc gccgtatcag caaaaccaaa aaagccatct atcaagcttt tatacaactt
    22921 ttgaatgcta agggctacga ggccactact gttcaggata tcattgatct cgcagatgtg
    22981 ggacgatcca ccttttactg tcactatgag agtaaggagc ttcttctgga ccagctctgc
    23041 cgctacctct tccatcatct ttttgaaaga gagcaagcca tttcaaccga ggactacctc
    23101 gcccacctct ttctgcattt tcataaaaac caagaccata tcaccagtct gctattttcc
    23161 aaaaatgact acttcctccg tcaactccat aaagagctag aacaccatgt ctattccgtg
    23221 ctagctgata atttaaaaga agcccaccct aatctgccta cttcttacct ccaacacttg
    23281 gtcatgtcca actttatcga gacattgacc tggtggctca aaaaaggtca agatttcaca
    23341 gaccaggaag ttgtccaatt ttatctagac cttctcattc ctaaaaattg aatatagagt
    23401 aaagctcagt tgtcttattt ctagattact gagtttttta tcttttcaac aacaaaagag
    23461 gacccgccga tcctcttttt catactataa atccttgatt atcaactata tctgttttaa
    23521 tcgaaatctc aaaacagcac tttcaaacat cttttcctag ttaagtaaat cagtattctg
    23581 cttagctgcc ttgctccatt gataccaacc aactagactg ttaatgagat aaattagata
    23641 tttcccttga atttgcaggc tttctcccca ccagagatag attgaaaaga cattggtagc
    23701 cgcccagaat atccactgtt cacggtaaac agctgtcatg aggatttgcc ctaccccatt
    23761 ggttgcatct gtgattgaat cacgataggg acgattggca ccaatagact gataaatgaa
    23821 gccaaaggcc aaccaccaaa gcacactaat ggaaagatac tttgtccagc ccttgccgtc
    23881 cagtttacgc gcgacaaact cctgcttttc cttcttaaac tgtgcctgat aaatccaaac
    23941 tagaagtcca attggctgca tgactgtgaa gtaaagtgtc gtcagcacct caccataaaa
    24001 gcctttctgt agggccaaaa taaggtaaat aacagagtta atcaagccaa aaagataatt
    24061 acttgctcga ccttccgata caaagattac acagataatc cctgtcaagc tacaaatcat
    24121 cccaatccag tcaacaatac gatgttcgta aaccaactcc agccagagag gaaaacttcc
    24181 taaaaccagc aaataaatcc actgggcaaa actacgatgg gcaaagaggt catcccagat
    24241 agccttcata gttcctgaaa atcctaaatc agccatagcc gcaaccatac gacggtaacc
    24301 acctgacatt tcacctaggg ttgttttgat attttcaatt ttcttttgca aataagtatg
    24361 catcatttct ccttttgttt ttaaagagcc gtgtctggat agactttcgg acgcaacgct
    24421 ctattagata atgaactgcc tatacacaag atttctaacc ttagtcgaca tgagctgaaa
    24481 cctcttattt gttaagtagt tcacaaaata ttatacacct attttatgaa tagtcaactg
    24541 tctttacagt aaaattttag aaaatcatga aaattttctc tttctttcca ttttaagtga
    24601 cattcagtca ttctcacatc aaaaaagccc agacgaaatt gtctgagcat tcttttatct
    24661 agtcgtttaa ggaagttgag ttcagtatgt ttaaagtctc tgtcccatca tttcttcaac
    24721 aaaccttgtt cttggagaaa ctccttggct acttgctctg ctgacttgcc ttcaacaccg
    24781 acttggtagt tgagctggct catctggttt tctgtaatct taccagccaa tgtattaaga
    24841 actctttcca actctggatg tttcttgaga agagcttctt tcatgagtgg agccccttga
    24901 taaggtggga agagttgctt gtcatcttcc aagacctgta aatcataacg ctccaattcc
    24961 gcatcagtcg aataggcatc cgtgatttga atatcccctg actgaattgc ctgataacga
    25021 agagctggct gcatagtcgc cacattgaga ttgagaccat acattgattg caagccctta
    25081 tttccatctt cacggtcgtt aaactcaagc gtaaagcctg ccttcagctg cccttccact
    25141 tttttcaaat ccgaaatggt cttcaagcca tattcttgag caatcttttt cggaacagct
    25201 acagcatagg tattttgata agacataggt ttgagatagg ctagatgatc ctgcttggca
    25261 atgccatcac gcgccacttg ataaacctgc tctggctcat gactcacctt gggtgatggt
    25321 tgaagcaaac tttcagtcac cgtaccggta aattcaggat aaatgtcaat atcacctttt
    25381 ttcagagctt cataaaggaa acttgtcgtc ccaaaattcg gtttaacagt cgcagtcatg
    25441 ctggtatttt cttcaatcag caatttatac atattagcca aaatttctgg ttctgggcct
    25501 attttcccag caataatcaa gttttccttc tctttttgag ccaaaagggc tggactataa
    25561 gacagaccca gtaataaagc caccaaggca aaaccagaga aaatcgtccg caatttcgct
    25621 ttttccatta cttttagtag gaagttaaag gcaatagcta gcactgcaga agaaagtgcc
    25681 ccaatcaaaa tcagactggc attattacgg tcaattccca aaaggataaa ggaacctagt
    25741 ccccctgccc caatcaaggt cgccaaggta gccgtaccga taatcaagac cgctgccgtc
    25801 cgaattccag acatgataac aggcatggca agtggaattt caaacttctt gagacgctcc
    25861 catctggtca tcccaaaggc aatcccagcc tcttgcagac tcggatcaat tccattcagc
    25921 ccagtaatag tattttgtaa aatcggaaaa atcgcataaa tcactagagc tgtcaatgcc
    25981 ggtaaagtcc caattcccat caaagggata aagagcccca acaaggccag agacgggatg
    26041 gtctggaaaa tacctgcaat ctgcaagacc cagtcggcca gcttctcatg atagcgaaga
    26101 taaacagcca agggaatcgc aagcaaaata gctagtaaca aggtcaaaag tgacaactgc
    26161 aaatgttgag atagggctgt caaccaatca ccaaaacgat cctgaaaagt tgcaattaaa
    26221 ttagtcatga atactacctc caaacaagtc tgcaacaaag tctgttgcag gagcttttaa
    26281 aatagtctca ggattcgaca cctgacgaat ctctccatcc tgcaagacag caatacgatc
    26341 tgccaacttt aaggcttcat ccgtatcatg agtcacaaaa atcgttgtca tcccaaactc
    26401 tttatgtaat tcttttgtca gaacctgcaa ctgttttctc gaaatagcat ccaaggctga
    26461 aaagggttca tccatgagga gaatcttggg ctgaccaatc atagctcgga caataccgac
    26521 ccgttgctgt tctccaccag atagctcact tggaagtcga tgcccatact cagctactgg
    26581 taaaccaacc ttagccaaaa gctcttctgt tttttgagca atttcttcct tagtccaacc
    26641 cttcatttca ggaatgagag caatattttc ctcaactgtt agattgggaa agagagcaat
    26701 agcctgtaaa acatatccag tagaaagacg aagttcacgc tcatcatagt ctttgatgcg
    26761 cttcccatcc atataaatat ttccatcagt tggttccaaa agacggttaa tcatcttgag
    26821 catggtcgtc ttacctgacc cagaaggccc tactaaaacc ataaattccc catcctcaat
    26881 ctgtaagttg acatctctca agacatcctt ttctgtgtag cgcagtgcta catttttgta
    26941 ttcaatcatt ctttgtcctc aatttaaaac ttccctcgat tagtcaagtc ttctacctta
    27001 ggcatgactt ccttattatc ccaatgctcc acaattttcc cgttctctaa acggaagata
    27061 tcgtactggg cataagcaac gccatcaatc tgagtctgac catagctaac cacatagttt
    27121 ccttgtccta agagttggaa aacaaagtca aaagtgacac tatattcagc cacatagttt
    27181 ttataagcag cacttccttg tccaatctca tgattatgct gaatcaaatc gtctgccaca
    27241 taatcactcc actgctctag ctccccattt tggaaaattt ctgtcaagaa acggcgaacc
    27301 agctttttat tttctgcttt cttatccaaa tccttgattt caaaatctcc aaaaatttga
    27361 tctagttggt cattttcagg tgttcgatag tagtcaatga catcccaatg ctcaacaata
    27421 cgaccattct catccgcacg aaaagtatcc gtcgtcaccc attgagcttc tccaccattc
    27481 agatattgat gaacatgaac aaagaccaga ttgccatcct caatggtgcg gacaatctta
    27541 atctgacgct ctggatgacg ctcaaagaaa tctgcaaaga aggctgcaaa tccttctttc
    27601 ccgtcaggaa cacctgtcga atgttggata taggtatccc ctacagactg ggcttgagcc
    27661 tcagcaactc gtccgtcttg aatggcatgg atgtataggt tgtgagcatt tttcacttgt
    27721 tgtgacatat tctaaacctc atttcccttc tctttcaaat tcgccaaaat tctttcttga
    27781 aaaccttcaa attggtgaat ttcttcctct gaaaatcctt tgtaaaagat agtatccaat
    27841 ttctgactga cacgatgccc cacttctttc tgggacttgc ctaactccgt taaaactaaa
    27901 tacttcttac gcttgtcttt tccacacgga ctaacaatta caagcttttg ttcctctagc
    27961 ttttttatca tagtcgtcag cgtattattc gcaagcccag tcgcaagcgc gatatctgtc
    28021 gcagttgcgc agccagtttc actattccat aaaaccgcta aaatcttgcc ctgttcaccc
    28081 ctataaagag cctcaggatc ttgactcagt aacttttgaa aaatccgccc attcaacaaa
    28141 cgaatatgat gggctagcaa atgaccatct ttcataacac ctccaattta tttcgatatc
    28201 gaaatgaata aaacaattgt aacactcatc gttctaactg tcaactattt cgatttagaa
    28261 ataatttttg ataattatcc acaccaccat actccggctc aactaacttt taacgagagt
    28321 ttctaaactc cttcgtcctc cagtctacaa aagccttcca ttcgtactat cctatatttt
    28381 atgaggggac acatttttcc tatcagacca tttattttaa agatagaagt aaatcataat
    28441 tgcttccatc tgttctttta tagtatattg aagttagact agagcactgt atcttctaaa
    28501 acattgatag aaagcgattt gaatttccca atcaatttgt tcgtatttat agcatttcga
    28561 aactggaata ggacaccatg actgctaaaa gatttctata aattcatttg attttcctaa
    28621 tcaatttgtt catatcttat ttcattccgc tataatttca ccttacccta tctttttcgt
    28681 agcacccttc aaacagccta tcccctaccg tttgacgatt cctcacttcg ctccacttcc
    28741 attacagaag tttcttcact actatgggct cggctgactt ctcatgattc cttgttacta
    28801 ctatttgaac gctcacgaga tagatcttac aaaaaatgct ttgatccaca atggaatcaa
    28861 agcattttaa agagttcctc atacataagc gcagaagtcg cagttcctct gtacttggct
    28921 tcttctcttt tgataaagcg agccaagttg agcaactcag gtgctggatg tttgggattt
    28981 aggagcaatt cacgattgac caggcctgag agacgaactg cctgcaattg ttcatttgta
    29041 gtaggcagtt ttttagcagt ctctaggaga gcagcaacta aatcttcact caaatcatgt
    29101 cgagcatgat tgtaaagatc ttttataagg ctttctaggt ttggttctgc catccctacc
    29161 acctccctta tggtttaata atgtttaatc aaatcaaccg ttgaacgatc caatttcttc
    29221 accaaggctt gtaagaaagc ttgcgcttct aggaagtcat ccattgcata gagggtttgg
    29281 tgagaatgga tataacgagc gcagacaccg atagttgttg atgggacacc accatttttc
    29341 agatgagctg cacctgcatc tgttccgcct ttaccacagt agtattggta cttgatacca
    29401 gcttcttcag ccgttgtcaa aagaaaatcc ttcatccctg ggagaagcaa gtgacctgga
    29461 tcatagaaac gaatcaaggt tccatctcca attttgcctt gaccaccgta gacatcacct
    29521 gctggtgagc aatcaactgc gaggaagact tctgggtcaa acttggttgt agaggtatga
    29581 gcgccacgca gaccaacttc ttcttggacg ttagaaccca gatagagttc attgccgagt
    29641 ttttgacctg ataaagcttc agctagctcg cttaccatga ggacaccgta gcggttatcc
    29701 caagcttttg agatgatatt tttttcattg gctgtcaaaa ttgcagaact atctggtacg
    29761 atggtatcac caggacggat gccaaaactt tctgcctcag ccttgtccgc aaaaccacca
    29821 tcaaaaacga tatcggcaat ggctggcatg gttggtcccc cctttccacg agtcaaatgc
    29881 ggaggaacag aacctgaaat cacaggaatt tcatgaccat cacgagtcaa gagtttgaaa
    29941 cgttggctgc taaccaccat ggggttccag ccaccgattt ctacgacacg gaaggtacca
    30001 tctggcttga tttcgctgac cataaaacca acttcgtcca tatgagaagc gaccaagacg
    30061 cgcggtgcat ccacagcttc tgaatgtttg ataccaaaaa taccacccaa gccatctgtc
    30121 accacttcat ccacatacgg tgtcaacttt tcacgaagat aagcacggac aggcgcttca
    30181 tgacctgaga ctgcagcaag ttctgttact tctttaattt ttgaaaataa tgttgtcatt
    30241 tcagttcctt ctttctttca tccattttac cactttttat aggagaagga tagtgggaag
    30301 gtggatttct aagttagtat cttagtcctg ctctatctta gaaaaggata gtattctctt
    30361 gcatgtagtg caaaatctag taaacattcc aaaattaact cgaatattta tttccaaaca
    30421 aaaaaacaat acaccatcaa agttgtttag atttttcatg aaatttacag aaaatagttg
    30481 acttcccttt cttctttctt taaatatata gttggttgag tttggaatag tacgctgtag
    30541 ctgctaaaac atttctagaa attaatttga ctttcctaat agagttgttc atatcttatt
    30601 tcaatttact atagtacaaa actagaaaag gaaaaaatca tgaccaaaac aattcttgtt
    30661 acaggtggga ctagctacat tagctcccat accgttaaag ctcttttaaa tgctggctat
    30721 caggtgcatg tcctcgataa tctctccaca ggaaatcgag cggctgtgga tagtcgtgct
    30781 agctttaaag aactggatgt ttatgatgct agcgccttaa aggcttactt agaagaaaat
    30841 cagattgatg ctgtcctcca ttgtgcaggt gaaattgttg tgagcgaaag tattgaaaat
    30901 ccaagtaaat acttcactgc caacgttgct ggtatgaacc aagttctcaa agtcttatct
    30961 gaagttggca ttcaaaaaat catgttctct tcgactgctt ctctctatgg aaataactgt
    31021 attgacaagc cggtgactga agataccctg ctcgaccctg tcaaccctta tgcagagaca
    31081 aaactgatgg gcgaacgaat gatttactgg atggccaatc gctacgactg gaaatatgtt
    31141 attttccgtt actttaatgc tgctggggct gaaatggatg cttcaaacgg tctgcgtgtg
    31201 aaaaatccaa ctcacatcat tccaaatatc aacaagaccg cattgggaca aaatgatagc
    31261 ttaaaaatat ttggagatga ctacgataca cgtgacggtt catgtattcg agattacatt
    31321 tatgtcttgg accttgcata ggctcatgtt aaaggaatga actacctatt tcaagaagac
    31381 agttcttctc aaatctttaa cttaggaact aaaaaaggct atactatcaa agaaatcttt
    31441 aaaactgctg aagaattact aaattaaaaa atcccacacg agattgttgc tcgacgtgct
    31501 agtgacccag ccagtgtcct agcagatgct tcaaaagcta aacaatatct tgattggacg
    31561 gctagctact ccctcgaaga tattatttta tcagattaag gtaaaaacat tttagaatag
    31621 gataacaaag gagaaagtct tgttgctctc tccttgttgt atttattaaa ttatcagaaa
    31681 ttttattgac agattagaaa aataatgtta catttatatc cgcagatatc tttcgatacc
    31741 aaatctacat gaaaggacgg ggtatgaaac tttctcatta tttaattggc ttacttctac
    31801 tcctagtctt tctctctatt agcattggga ccagtgattt ttcatgggga aagctatttg
    31861 atttcgacca gcagacctgg ctcctctttc aagagtcccg tctcccaaga actatcagta
    31921 ttctcctgac tgcctctagt atgagtatgg caggccttct catgcagact attacccaaa
    31981 atcagtttgc tgcaccgagt acagttggaa cgactgaagc cgccaaactg ggaatggtgc
    32041 tgagcctttt tgtctttcca tcggctagtc tgacccaaaa gatgctcttc gcttttgttt
    32101 catccatcgt attcaccctc ttcttcctag cctttatgac catttttact gtaaaggaaa
    32161 ggtggatgtt gcctctgatt gggatcatct atagcgggat tatcggctca gtcacagaag
    32221 ttatcgccta tcgtttcaat ctggttcaga gtatgactgc ctggacccag ggctccttct
    32281 ccatgattca gacccatcag tatgagtggc tcttcttagg cctcatcatc ctgataaccg
    32341 tttggaaatt atcccaaacc ttcaccatca tgaatctggg gaaagaaacc agcgagagtt
    32401 tggggatttc ctactcccta cttgaaaaac tggccctctt tctggtggcg ctaacgacaa
    32461 gcgtcaccat gattaccgtg ggtggcttac catttctcgg agttatcgtt cccaatcttg
    32521 ttcgcaagcg ctatggagat aatctaagtc aaaccaaact catggtcgca ctggttggtg
    32581 ccaatctagt tctggcttgc gatatcctat cccgagttct gattaggccc tatgagttgt
    32641 ctgtcagtct cttgctagga atcatcggta gtctcgtctt tatcctactt ctctggagag
    32701 ggggacgaaa agatgcagac taaaagcaaa cataccaagc tcttctggat tctcattatt
    32761 cttgccatcg gagcttgtct tctctacttt tggcccatca ctcacttgtc agcctttgct
    32821 tggaagttgc gttcccaaaa gatcatcgtt tatctcttgg tagccatcgc gactgggatt
    32881 tcgaccatta gttttcaaac cctgacggaa aatcgcttcc tgacgcctag tattttggga
    32941 attgaatcct tctacgtcct actacaaacc ctactactgg tttttgaaag caagtttctt
    33001 caacttggca aatcccctat cttagaattc ctagtcttac ttcttgtcca gtccttcttc
    33061 tttctcgcct tacaaggtta cttgaagaca ctgatgaagc aagacctggt cttcatcctg
    33121 ctgatctgtc tagcgctcag aagtctcttt cgaaatatca gcaccttcct tcaagtccta
    33181 atggatccaa acgaatacga taaactgcaa aatagtcttt ttgcctcctt tcaacatctt
    33241 aacacttcca tcctagccat cggttctctg atcatcctcg ctttgacaat ctttttcttt
    33301 cgaaaagcag tcgttctaga tgtcttgcac ctgcaaagag aaacggctca gatattggga
    33361 ctcgatgttg aaaaagaaca gaaagagctc ctctggggaa tcgtgctttt gacctcaacg
    33421 gccactgcct tggtaggacc tatggccttc ttcggcttta tgctggccaa cctcacctac
    33481 ctgattgtca aagactatca gcacaagtta ctctttatag tggccattct ggttggattt
    33541 attagcttaa ccttggggca agccttgatt gaacgagtct ttgcactgga aattcgtatc
    33601 agtatgatca ttgagagtgt gggtggcttc ttattcttta tcttactata taggaggtct
    33661 cgtcagtgaa actggaaaac attgacaaat ccattcaaaa acaggatatt ttgcaaggca
    33721 tttcgcttga agtcagtcct caaaaactga cagcctttat tggtccaaat ggtgctggaa
    33781 aatcgactct cctctccatc atgagcagac taaccaagaa agatcaggga gttctcagta
    33841 tcaaaggacg tgaaatcgag agctggaatt cgcaagaact ggctcaagaa ctaaccatcc
    33901 taaaacagaa aatcaattac caagccaaat tgactgttga agaactggtc agttttggac
    33961 gttttcccta cagccgaggt cgacttagat cagaagactg ggaaaaaatc cgagaaactc
    34021 tgaactattt ggaactgacc aacttaaaag accgctacat caatagcctg tcaggggggc
    34081 aactccagcg cgtctttatc gctatggtac tggcccagga tacggacttt atcttgctgg
    34141 acgaaccact caacaatctc gatatcaagc aaagcgtcag catgatgcag attcttcgac
    34201 gactggtgga ggaactcggc aagaccatta tcatcgtcct ccacgatatc aacatggcca
    34261 gtcagtatgc agatgaaatt gtcgccttca aggacggcca ggtctttagc aagggaagaa
    34321 ccgatcaaat catgcaggct gacctgctca gtcaacttta tgagattccc atcacgctag
    34381 ctgatatcaa taacaaaaag atctgtatct atagctagta acataaaagc tcaagttaga
    34441 gaaccttcag tctcttagtc aataagatta agagactccc taaatcgtta tcacatttta
    34501 aaaaggagaa attatgaaaa catcccttaa actttatttc actgccctag tggccagctt
    34561 cttgctccta cttggtgcat gtagtacaaa ctcaagcact agtcagacag agaccagtag
    34621 ctctgctcca acagaggtaa ccattaaaag ttcactggac gaggtcaaac tttccaaagt
    34681 tcctgaaaag attgtgacct ttgacctcgg cgctgcggat actattcgcg ctttaggatt
    34741 tgaaaaaaat atcgtcggaa tgcctacaaa aactgttccg acttatctaa aagacctagt
    34801 gggaactgtc aaaaatgttg gttctatgaa agaacctgat ttagaagcta tcgccgccct
    34861 tgagcctgat ttgattatcg cttcaccacg tacacaaaaa ttcgtagaca aattcaaaga
    34921 aatcgcccca accgttctct tccaagcaag caaggacgac tactggactt ctaccaaggc
    34981 taatatcgaa tccttagcaa gtgccttcgg cgaaactggt acacagaaag ccaaggaaga
    35041 attggccaag ctagacaaga gcatccaaga agtcgctact aaaaatgaaa gctctgacaa
    35101 aaaagccctt gcgatcctcc ttaatgaagg aaaaatggca gcctttggtg ccaaatctcg
    35161 tttctctttc ttgtaccaaa ccttgaaatt caaaccaact gatacaaaat ttgaagactc
    35221 acgccacgga caagaagtca gctttgaaag tgtcaaagaa atcaaccctg acatcctctt
    35281 tgtcatcaac cgtacccttg ccatcggtgg ggacaactct agcaacgacg gtgtcctaga
    35341 aaatgccctt atcgctgaaa cacctgctgc taaaaatggt aagattatcc aactaacacc
    35401 agacctctgg tatctaagcg gaggcggact tgaatcaaca aaactcatga ttgaagacat
    35461 acaaaaagct ttgaaataag ccacttcaaa ctcaatttaa tactcaatga aaatcaaaga
    35521 gcaaactaga aaactagccg caggttgctc aaaacactgt tttgaggttg cagatgaaag
    35581 ctgacgcggt ttgaagagat tttcgaagag tataaaattt tgacattcta aaacgcatcc
    35641 tatcaagttc actcaaacct gataggatgc gtttttatca ttttgaaatc tatttacccc
    35701 acctcattcc ccttcttgat ttcgtttaag ggaaaagcgg tctggaacgg ggtccttacc
    35761 tgttttcgac cagggatgac aacgtaaaat ccgagccaag cccatcaata cccccttaaa
    35821 accatgtttt tcaatagcct gaatcatgta gttggaacaa gtcagctcaa agcgacaaga
    35881 gggtggaaag actggtgaga taaaacgttg gtaaaagcgc acaggcgcta ttaaaattcg
    35941 tttcattatt tcttagttac agccatggtg tgtagttggc tgatttcttt tttattaaga
    36001 cgacgggatt ctcctggacg gagtcctgtc aagtctaggt gtccgaaacg agtccgagac
    36061 aacttatcta cttggagacc aacagcttca aacatctttt taacctgatg gttacgccct
    36121 tcatggatgg tcaactgcac cacagagcga tttttgactg ggtccacttt gagaatttca
    36181 taaacagctg gcttggtttt cttaccatca atctcaagac cacgggtcaa ggggcggaga
    36241 ttgtccttat tgaccacacc tttaacacgc gcgacataaa ccttgtcaat ctcattacga
    36301 gggtgaatca tctcgtctgt aaagtcccca tcattggtca aaatcaagac acctgatgta
    36361 tcccagtcca aacgacccac agggtaaata cgctctttga cattgggcaa gaggtcgaca
    36421 accgtcttgc gacccttatc atctgtcaca ctggaaatca caccgcgtgg tttgttaagc
    36481 agatagtaga ccttttcttc gttgtagata ggttgacctt caacttcgac cttgtcgcct
    36541 gacttgatag tggttgctag ttcacgcacc acttggccgt taaccgtcac caagccttgc
    36601 ttaatcagct cttctgcttt tctcctactg gccacacctg cgtgggcaat atacttattg
    36661 attctcatct tcttctatcc tttcaccaaa taattggctt tcttgggctt gaatctcaag
    36721 ctcatcaatc actggtaatt cttctaaatg gtttatcccc atgtaatcta ggaaataatc
    36781 cgtagtcaca tagaggttgg ggcgccccaa tacttccttt ttcccgtctt cctttatcag
    36841 gtcaaaagcc tgcaactttg ccaaggctcc actcgagtta actccacgga tggcatcaat
    36901 ttctatccgc gtaatcggct gtttgtaggc aataatggac aaggtctcaa gggcagcccg
    36961 agacaagctc tggttgatag gcgccttaga gtattccttc aaaatctctg caaattgagg
    37021 cttggtcacc aatctataag caccacttgt ctcaatcaaa gccaaactgg aatctgggtc
    37081 cttttcatac ttctgggcta attttcctaa actttgctgg atgcctgtcg gtggcagaga
    37141 gaggagttca gctaactggc ggacccgaat cccatcttca cccgctacaa acaagagcgc
    37201 ttctattttt gctaaagtac tcatctttcc tctctatcaa gtctagcttt gaggcacttg
    37261 actttcttcc ttcttttcca tgagatagat atctccgaaa ctctcctctt gcacgaggat
    37321 cagctcctgg gttttgatta actctagggt tgccaaaaag agggtgatga cctcttggac
    37381 attctgggct tccttgaaca aatcctgcaa gcgcaattga tctcgtccaa tcaaggactc
    37441 tttcacgata atcatcatgt cctcaatctt atactcatcc cgcaagatcg tcgtgtgatt
    37501 ttgtgcaaac tcctcttttt tcttggctag gatatttgaa aaagccaaaa agaggtcaat
    37561 ggtcgtcttg tcatgcacaa gctccgcatc ttcgtaaatc aactctgtcg gcgctttgga
    37621 ataatactgg gcccgttctt ggtgcttggc ttccaagtgc tcacccaaga gcttgaactt
    37681 gcgatattct tcgatttgag agaggaggtc ctgctccagg tcatccccca agtctgtcac
    37741 ttctgctacc ttcggaagga gtttacgact cttaatcagc atgagctgac tagccatgac
    37801 catgtactca cccgtcactt ccagacgcat ggcctgcagg gttgagacat aggctagata
    37861 ctgttcgatg acttccgtaa tgggcacatc gtagatatcc atctggtact tagaaaccag
    37921 atgcaagagc aagtccaggg gtccttcaaa atcttttaat ttaatatcca ttatctatat
    37981 ttttctaagg tcaggactgt ttttaatcct aatttttttg caatttcgta caaatcgacc
    38041 ttgttttcta tttgtcttag aataaactgt tcacgtaaga cttgagctga taaggatgga
    38101 aaacctttct ccttgacaaa agattctaac tgacgaaagg cccactgacg agaatagggt
    38161 ttctctcctc tttcaaaaag ataggtctgc cccatcaagg gttccaattc tgaaagcaag
    38221 gccgtgggaa tggtgacaat cctctgttgg gaagccttgc tgattcgcaa cacctgaaaa
    38281 tccagattga tgtccgcaac cttgatggct aaaatctcac tgggcaaaag ccccatttct
    38341 aggattaaga gcgctagcaa gcggccctct ggatggtcgc tttcctgcca aaaagagtct
    38401 aggtatagaa tctctggctt ttccgtcttc ttttcagctt gtttggctaa ttccaagcgg
    38461 taaaagctgt ccacctctcc tttttgatag agaaagtata gaaattggtt acaggccgaa
    38521 atctttcgct tctgggcgct gatttttaga ttggctagct gggcttggta aatcttgaga
    38581 ctggtctcag aaatccgctc acctaccatg tctaaaaatt gctccaaatc atacttatag
    38641 gactgcttgg aattgacaga caagccctgc ttttcctcta aaaaggctga aatcctgtct
    38701 ctcattggca tcgaatctca tattccttac taaagtcatg caagagggca ttaacggcct
    38761 tgaggatgga cttgcgcgta ataatccctt ggaaaatacc ctctgcatcc acaaccggta
    38821 agaaggactc atctactagc ttgtgcaaga cctccgtaat ggtgaaatca ggcgaaacaa
    38881 ccgctacgtc cgtttttgtc atatgaacga tatccgtatc cgccatgatt tcttggctca
    38941 agtcatgctc catctgatag gccataatat ctctgagtcc aatcgtccca acaaactgtt
    39001 tttcatctgt cacaacggga acacgggtat aggtcatctg actgagcaag agggtcgcat
    39061 gatccgcatt gtgggtatca atcaacacag ctagattttt agcaggggtc aaaaaagttt
    39121 cctcctgccc caacaagaaa gtctcaaact ccttggcaat catcggctaa actccttgga
    39181 caaacctgga tacacctcgt gatctcgtgt caaaaagtcc actttgaagt aactatcatc
    39241 aatctccaca cgagcataga gacattctct gatggtacct cgtggttggc tgatagaacc
    39301 tggatttaga aagaggatct tgccttccat ccaagcactt ggcacatgca agtgaccata
    39361 gaggcagata gcggcctctt cctcctgagc ccagtagtcc aacttttgaa agttgaaatt
    39421 gatgtcaaac aagtgaccat gagtttggat aatcttggtc gaaccaagct cagtcaccag
    39481 acgttctggg tagccggcgt agaagtccat gttcccttta acaacgcgga tgccctccca
    39541 aagtggagaa tccggacgta gttcagaatc gccgttatga aaaacggcat cgactttgcc
    39601 cacatagcga tcacggactt cttccacaat caagctatcg ccatgggaat cgctcattac
    39661 aatgatggtt tgctttgcca tgatggaaat acctccaaaa gtttcttaac ggctaaggca
    39721 cggtgagatt gactattttt ttcttccagg gttaattcag ctgatgactc acctgtctct
    39781 cctacaagga agaggggatc atagccaaag ccattttcac ccttaggttc aaagttaata
    39841 taacctgacc agtctgcttc aacaactaaa ctttccttat ttgggctggc tacgactagg
    39901 gttgtgtgga actgagccga gcggtccttg agttcaaaga ccatggccaa ttcgtgcaag
    39961 agtttggcat tattttcacg gtcagttgct cccacacctg cgaaacgagc tgaccagacg
    40021 cctggtaagc caccaaggac atcgactttg agaccagaat catctgccaa aaccatcttg
    40081 cccgttaatt gagaaatggt ttctgcctta aggcgggcat tttcttcaaa ggtcatacct
    40141 gtttctgcta cttcaggcag gtcagggtag tcattaagat tttccacatc gtagcctaac
    40201 ttatcaaaga tagctcggaa ttccttggtt ttaccttcgt tacgagtcgc aatcaacaag
    40261 gtttctctga ccttgcttgt ctcaaagaaa tcatgaacat tgaccccttc tttaggcaat
    40321 tctacataca agagttgccc attttcaacc aagagcaggg ccccatgacg ttgaataact
    40381 tccaagtttc gtcccatttc ttgattaagc atgtctacca caaaggagaa caaacggtag
    40441 gtagaaccat agcgtaaaac agtaactgaa agcgggaaac catactcttc atctccaaat
    40501 attttggaga attcaaacag aggaaaatct gtcttatagt cgctcaaact gttaacgcca
    40561 ccaaaaatac tataagaccc aacataccag tcccggtcat ccttatattc ataaatttta
    40621 tttgtcataa ttctacatgc tccacatgaa tctctttttc cagccattct tcaccaattt
    40681 gtgcaaaact ttggctactg gctgttgtgt aaaaacggtg atggagtggt ccagcatcgc
    40741 gaccacgatt gatttcaaaa taattgagta agactgagat atcccgtacg cactctgccc
    40801 cactatcgat gagctgaacc tttggcccca tcacattttg gataataggg cgaaggagtg
    40861 gataatgagt acagcccaaa atcaggctat ccacctttcc aaccaaggga cgcagggttt
    40921 catagaccac cttcttggta acactggttg acagggcacc tgactcaacc aagggagcaa
    40981 acttgggaca ggccaagctc tccacctgta agtcgggatc cagatcatgg attttctgac
    41041 ggtatatgtc tgattgtacc gtcatgggcg ttccaatcac tcctattttc ccaccttgac
    41101 tggacttgat ggctgccgaa gctcctggca aaattacacc caagacagga atatctagtt
    41161 gagccttgat ttcttcccag acgaccgcag tcgcagtgtt acaagcaatg acaatcattt
    41221 tgacatcctt ggtcaagaga aagttgacca gctgccaagt atattcacga atttgctcag
    41281 caggacgggg gccatagggc gcccgcgccg aatctccaat atagacgatt tcttcatggg
    41341 gaagctggcg catgagctcg cgcacaacgg tcaagccccc gacacccgaa tccaaaaaac
    41401 caattggtcg attatccata cagtcttctt tctagtcttt tttctgattg atcgttcatt
    41461 atgattcctt gtactgaacg aactgaccga cagcttgata gaatgtcaac tacctctctc
    41521 ttaatcataa tcaaatatca atagaatgca aggaaaaagt ctcatcccta aaccataacc
    41581 aacatagtga gaagtctgga actttcatcc cagacttttc cttatttatt ttttcttttt
    41641 attgttagca agggctgcct tttgttggcg gatgatttgg tggtaaactt gttgtacctt
    41701 agcttcgctt ggtttttgac catttgcact caaaagagta cgaactgctt cagcattcaa
    41761 acgtgggttg tcagcaaatt ctttttcgat ttgcttacga accaagtaca ttcctccaag
    41821 agctcctcct agaaaagcta gcacaatcaa tacaattgct aaaagtaaat ccatcatttt
    41881 tctcctgttt ctttttgagt ccctttcatt ataccacaaa ctagccaccc tgaccagttt
    41941 gttctacact ttcaaggatg gaatagacag caaaaagaac cctgcttttc tgaaaaagag
    42001 gtctccttgc taagtttata ctcaatgaaa atcaaagagc aaactaggaa gctagccaca
    42061 ggttgctcaa agcaccgctt tgaggttaca gataaaactg acacggtttg aagagatttt
    42121 cgaagagtat taatttacat aaatagccag tgtttgatag ggtttgagta gaattttctc
    42181 agacacttct gcatcttcat agtttgaaat caaaatctgt ccattttggt agactgctgg
    42241 caagtcgatt tccacttctt tggcataaaa gttattgagc actagtaact tttgatcctc
    42301 aaactggcgt tcaaaagcgt agacttgttt gctatcttca aaggctggtt tgtaatttcc
    42361 ttctgaaatg attggcattt ccttacgcag tcgaatcaag tcttgataga aggtgaaaat
    42421 cagacctttg atttcatttt ctacattgat atctttatag gatttaccaa ctttcaacca
    42481 tggagtgcct gttgaaaatc ctgcattttc agaagtatcc cactgcatgg gaatacgtga
    42541 attatcacgc gacttagctt gaataatctg gaaggcttct tgctgactct ttccttcttc
    42601 taagagcatc tgataggcat taagcgattc gacatccaca taatcagtca tagaatcata
    42661 gtctgggtca atcatcccga tttcctcacc catgtagata taaggtgtcc cacgtgacag
    42721 gtgaatgctg gctgctagca tggtggctcc ttccttgcgg aagttttgaa tatcgacaaa
    42781 acggttcaag gcacgtggtt gatcgtgatt gttccaaaag agggcactcc aaccgtcttt
    42841 atcactcatt tccttacccc aactatggta aagactcttc aactcttcaa aatcaaaggg
    42901 agccaaggtc cacttttgtc catccttata gtccaccttg aggtgatgaa aattaaaggt
    42961 catggataat tcctgacgat caggcgacga atagaggaca cagttttcca tggtggtaga
    43021 agacatttcc ccaactgtca taaagctatc gtcagatcca aaagtggctt ggttcatcat
    43081 acgcaaatag ttatgaacga tgggtttgtc tgtataagct ggcttccctt cattttcagg
    43141 acagtccact gaaacctcgt ccttaccgat caaattgatc acatcaaatc ggaaaccttt
    43201 gacacccttg tcgcgccaga aattaacaac cttgaaaagc tccttacgga cattggaatt
    43261 gcgccagtta aggtcagcct gggtctcatc aaataggtga agatagtatt tcccagtatc
    43321 cccgaaaggc gcccatgcag aaccaccaaa cttagactgc caatctgttg gttggtcttg
    43381 gatgaagaaa aagtcttgat aatacttatc accagctagg gctttctgaa accattcatg
    43441 ctctgtcgaa caatgattaa gtaccatgtc cagcataaag tcaatcttgt gctctttacc
    43501 gacacacacc atttcctcaa aatcagccat atcaccaaaa agaggatcca ctgccatata
    43561 atctgaaata tcgtaaccat tatcccgttg agggcttgga tagaatggat tgagccagac
    43621 catatccaca cctagtttgg ctaaataggg aattttttcg ataatcccac ggaaatcccc
    43681 aataccgttt tcagtggtgt ctttgtaaga ttttggatag atttgataga ctacttttcc
    43741 tttatcaagt gtcatctgtt tctccttttc tgataaaagg gaggaagcag tcttccgtcc
    43801 ctatttgtgc tatttcaatt atactcaatg aaaatcaaag aacaaactag gaagctagcc
    43861 acaggttgct caaaacacta ttttgaggtt gcagatagag ctgacgtggt ttgaagagat
    43921 tttcgaagag tattagattc gtgtagcgac catgagagat gctccagctt ggatcgttgt
    43981 cggataagtt ccaggaatag tcgctgtata agcatcttgg ttggtgatga taacaggagt
    44041 ttctgtcacc agacctgcag ccttaatgac atccatatca aaacgaatca gttgctgacc
    44101 aactgtaacg tgatctcctt ggactacaag actttcaaaa cctttgccat caagacctac
    44161 tgtatccata ccgatgtgga tgagcaattc aactccctcg tcagagacaa tgccgatggc
    44221 atgcttggta gggaaaagaa ccgtcactgt cccattaact ggagaggtca actcaccttg
    44281 gcttggttca atgaccagac cttgccccat gacacctgat gcaaaaatag gattcgtcgc
    44341 ttgactcaat tctttcactt ggccagttag tgggctgata atttctaccg aagtaagttc
    44401 tactggttca tggttcacaa attctgcttc ttcttgagca acgaattctg cctgcaagtt
    44461 cgtatcgccc tctgtttttg taaagagacc agccttgcgg aagaagaaag tcaagagcat
    44521 tggaacaaca atcgcaacta gcatagttcc tgcaaatggc agcatgtatt gaggttgaat
    44581 agagagaata cctggcaaac caccgatacc aatagaagcc gcagttacat taaaagtaac
    44641 ggataacatg cctgcaaggg ctgaaccagt catcccagca acaaatggat aaatatattt
    44701 tacgttaacc ccaaaaagag ctggttctgt aacaccgaga taggctgaaa tggttgcagg
    44761 aagtgaaacc tgagcctcac gctcatcatg gcgatgcatg aaataatagg caaacacggc
    44821 tgagccttga gcaatattag aaagagcaat cattggccat agggcagtgc caccagcatc
    44881 cgcaatcaat tgtgtatcaa tggcattggt catatggtgc agacctgtga tgacaaatgg
    44941 agcgtagagg gcaccaaaaa ttgcaccgaa gagccattta actggaccag ttaaacctgc
    45001 caagacaact gatgaaagtc cttgtccaat tgtccaaccg attggtccca aaacagtatg
    45061 agccaaaatc aaggctggaa tcaatgacaa gaaaggtaca aaaatcatag aaatgacttc
    45121 tgggatatgc ttgcgccaga agatttcaag ataagacaga ctcaaacctg caagcaaggc
    45181 tgggataact tgggcttggt aaccgatacg attaacagta aaatagccaa aattccaaac
    45241 ccagtttgcc gcgatatcag ctgctggcgt tgaagcaacc gcataggcat tgagcaactg
    45301 aggcgatacc aaacagattc cgagaacaat tcccaaaatt tggctggttc ccatcttacg
    45361 agaaacagac caagtaatcc ctactggtaa gaactggaag atagcttcac caggcaacca
    45421 gaggaagtga ttaacccctg cccaaaactg agaggattct gtgatggtct tgccatccaa
    45481 catcgaccaa tggacacctt ccaagacatt acggaaaccg aggatcaatc caccaacaat
    45541 caaggctgga ataatcggag taaagatttc cgccagagtg gtcataacac gttggaccac
    45601 gttttgatta ctcttagctg cagacttggc tgcttctttg gaaacaccct caatacctga
    45661 aacggctgta aaatcattat aaaagatggg cacgtcattt ccaatgatta cctgaaattg
    45721 acctgcattt gtaaaggttc ctttaacagc tggaattgac tcgatagctt taacattagc
    45781 cttcttatca tctcctaaaa caaaccgcat ccgtgtcgca cagtgagtta cggcagtcac
    45841 attttctttg cctccgattg cctgaagcag atctttggct tcttgttcaa attttcccat
    45901 ttgattctcc ttatacttgt caaagcaagt ttgatttgat aagtatattg taaacgatac
    45961 caaacttgtc tgcaacttgt ttggtataaa aagggtgttt ttttgtaaat tttctagcac
    46021 ttgtatggta aaatagatac aggtgttcat taaactagac taaaaaccta tttaagcagg
    46081 caaaatgaag aaataccaac aattatttaa gcaaatccaa gaaaccattc aaaacgagac
    46141 ttacgctgtc ggagatttcc ttcctagcga gcacgacctt atggagcaat atcaagtgag
    46201 tcgtgatacc gtccgaaagg ccctgtctct cctccaagag gaaggattga tcaaaaagat
    46261 aagagggcaa ggttctcaag tcgtcaaaga agaaaccgtc aatttccctg tatccaacct
    46321 aaccagctac caagaactag ttaaagaact tggactgcgc tctaaaacca acgtggtcag
    46381 tctggacaag attattattg ataaaaaatc ctcactgata accggtttcc cagagtttcg
    46441 gatggtttgg aaggtggtcc gccagcgtgt ggtggatgat ctggtatccg ttctggatac
    46501 ggactatctg gatatggaac taattccaaa tctcactcgc caaattgctg agcagtctat
    46561 ctattcttat atagaaaatg gcctcaaact ccttattgat tatgctcaga aggaaatcac
    46621 cattgaccac tcaagcgacc gagacaagat tctcatggac attggcaaag acccttatgt
    46681 cgtttcgatt aaatcaaaag tctatctcca agacggacgc caatttcagt ttaccgaaag
    46741 tcgccataag ttagagaaat ttagatttgt agattttgca aaacgcaaga aataaaagac
    46801 tgagacacca gatctcagcc tttttcttta tcccaaaact aattcatcac tgaccagact
    46861 ttggccacta tttttctgga agagatgcat aaggtcttca actgtcagat gctttttctc
    46921 ttctcccttg acatccacca ctatcttgcc ttgatagagc ataatgagac gattgccgta
    46981 ctcaatcgca tgattcatat catgggtaat catcaaagtc gtccactgat ggtgctccac
    47041 aatcttttgc gtcaagttca tcaccatttg actggttttc gggtcaagtg ccgcagtatg
    47101 ttcatccaaa agtaaaagtt ttggtttcat cagatctgtc atgactagag tcaaagcctg
    47161 tctttgtcct cctgagagat attgagtatc tacttttaag cggttttcaa gaccaatatt
    47221 caactccttc aaggcctctt ggaactggat tctatccttc tccttcacgc cccaaccaag
    47281 ccctctcttc tgcccgcgtc tcaaggcaat agccatattc tcctcaatcg tcaaacgaga
    47341 agctgttccc atcttaggat cttgaaaaac acgggcaata tccttggctc tctttctgac
    47401 actcagattt ttaatggatt tccctgccag tagaaggtcc ccttcgtcca ccgatagatt
    47461 gccagccaag atattcatca aagtggattt tcctgctcca tttccaccaa tcacagagat
    47521 aaaatctccc tcttcaacct ctaaatctaa tcctttgagg acatggttct cattgaccgt
    47581 ccctgcttca aatgtcttgt gaatattttc aagtgttaac aaacttgtca taactttctc
    47641 ctcctattca tttctcaatt tcagaccacg aatctttaat ctcttttgca attctggtgc
    47701 aaataaaacc aaagcgagca agattgcatt aaagagacgt accaagtttt gatctagatt
    47761 tggaatttca tagatattta aaataatcaa acggtaaaca atagcaccga ttccgatgga
    47821 taataagcgg cctccaatgg tcaagtcgtg tatcaagact tccgcaataa tcaccgagct
    47881 caaaccaaca acaatggttc ctgtcccaga agtcacatct gaaaatccat cattttgggc
    47941 aaacaaggaa ccacatagag caatcaaacc gtttgaaatc atgtaaccaa caatcttcat
    48001 ggtgtctaca ttgactccat tggcctcact catcgggata ttatccccag tcgaacgcaa
    48061 gaccaagcca atctctgttt tcatcaaaag ggtcaagacc aaacaaacaa gtaaaaaaca
    48121 ggccaaacta agtgagaaaa cagttccttc atttgtcaga cccaagctcg ccaactgttt
    48181 aaagacggtt gcagaatctc ccaaggaaag attgggtaca ctgcccatga ttttaatatt
    48241 gattgaatag agccctgtca aggtcacaat ccctgtcaag agagctggga ttttcatctt
    48301 ggtgtggagc attcctgata caagacctgc taccatacct gccagcaaag caagtaaagt
    48361 cgcaagccaa ggatttgccc ctgcctgtat ctgtgataca acgactgctg cccccagagg
    48421 aaaggctccc tcagcagtca tatccgcaat atccaaaata cggaaagtca agtagacccc
    48481 aatcgccaca atcgaccaca acaaaccttc tgataaacta gataacacaa aattcatctt
    48541 aatcctcctt attccttgcc ttctaactta ctaatatcaa ttcccaatgc atctgccatt
    48601 tcttgattgg tatgcaattc cagtttttca ggcaactcaa ctgctatatt ttctggtttc
    48661 tcacctttta aaacacgaat cagcatgcga gctgtctgac gtcccaattc ttcataattg
    48721 gttccgtagt tatacaagcc accaacagca atcatttctg ttgaaccacc gaatactgga
    48781 accttgtgtt taatagaaac ctgcttaact gtttccatgg ttaacgaaat gatattatca
    48841 gttgggacaa aaaccatatc cacctctgcc atcaaactct ctgctgccgc cttgacgtta
    48901 ttactgtcca agattgtttt ttcaacaacg gtaaagcctt tttctttcag aagtcgctta
    48961 gcttcatcct tttgaacaac cgaattgggc tcgctctgag tatagaggat tccaatcgtt
    49021 ttagcctttg gcaacacttt ctttatcaaa ttgatttggg ttgaaatggc atctgatgac
    49081 tgatcgcttg tcccagttac attgccccca ggatgttctc ttgactcaac caacttggca
    49141 ctgactgggt ctgttacagc tgaaaagata actggtgtcg tttgcgtcgt attggccaag
    49201 ctctgagcag aaggccttgc gatggctaga acgacatcgc tggattctgc tagttgctgg
    49261 gaaatcgttt ttagatttct ttgttctccc tgtgcatttt gcaaatcaat ctcaatattt
    49321 tccccctcaa catagccttg tttggccagc ttatccacaa atccttctct agtagcgtat
    49381 aaggactggt gggtaataaa ttgcgaaata ccgatacgaa agacatcttt ttcttatctg
    49441 ccttcaactg atgcaaactg atcagagaag tcaagaggag ccccactacc aagagggggc
    49501 tagtgatttt cgaacaactt tcataatgaa actccttctc agaaaagata aaacaaaaaa
    49561 ccgcctagat actatctaaa cggatacttg aaataaccta acaagttaca acttagctag
    49621 tccatttaga tattcatcta tatggaccac aatcaaaaat cttagccaca tagatacaaa
    49681 caaattgctt gaactgtttg catccatggt gacatgtcta caaacactat ctaaagtagc
    49741 taaagtaaaa gttttgattc atagttacgg cttgtctctt attcatttct ttttctgctt
    49801 tcttttttga tgcttcctgt cctaccacct ttttcatcac ctgtcaataa catttcataa
    49861 tttttaaaat ttttcaaaaa ttctttcagg aagctttcaa agtttttcaa atcagtccaa
    49921 caaaaaaagt tttataattt ccataaaaat tgacatggaa attataaaac cattactagt
    49981 ttagtccttt ttgataacgt gccaattcgg cttggttcgc ccaaacatag tgacctggac
    50041 ggatttctac catagatggc ttatcagtct catagtcgtg ttgacttggg tcgtaaacct
    50101 tcaagacctt cttacgttcc aagattggat ctgggattgg taccgctgaa agcaaggctt
    50161 gagtatatgg gtgaattgga ttgttaaaca attcttctgt ttctgcaacc tctacaataa
    50221 cacccttgta aataactgcg atacgatctg aaataaagcg aacaaccgac aagtcatggg
    50281 cgatgaagag ataggtcagg ccgagctctt tttggaattt tttgagcaag ttcaagactt
    50341 gggcacgtac agaaacgtcc aaggctgaaa ttggctcatc tgcaataaca aagtctggtt
    50401 gcatgaccaa ggcacgggca ataccgatac gttgacgttg accgcctgag aattcatgag
    50461 ggtaacgagt caagtgctca gcaagaagac ctacttcacg gataatattt tgaactttct
    50521 ctttacgttc ttcttcatcc ttaaataaac ggtgattgta aagaccttca gaaataatat
    50581 aatcaacagt cgcacgttca ttcaaacttg cggcagggtc ttggaaaatc atctggattc
    50641 gacgaatcaa ttccgcagct tgttcacgcg atttcttacc attaatcttt tgaccatcaa
    50701 aaatgatatc tccattactt gtatcattta gaccgatgat agcacgacca atagttgttt
    50761 tcccactacc ggactcacct acaagcgaga aagtttctcc cttgttgata aagaagttag
    50821 catttttaac cgcgacaaac ttcttacttc cttcaccgaa ggaaatttct aaatctttga
    50881 tttctactaa tttttcagac atttccttcc tcctagtcag ccagatgggc aaatcccatt
    50941 ttttcacgga tcttatcatg gagatttgca atcacagctg gtttttctac ttttggagca
    51001 tcctcatgaa gaagccaagt tttagcccaa tgtgtctctg atactgagaa ttgaggagct
    51061 ttttgttcga agtcaatctg cattgcgtag tcagaacgca aggcaaaagc atcccctttc
    51121 aggtcagtat aaagtgacgg aggtgttcct gggattgagt aaagatcccc tttatcatca
    51181 gcaagctgag gcaagctaga caagagactc catgtatatg gatggcgagg gtcatagaag
    51241 acttcctcaa ccgttccata ctcaacgatt tctcctgcat acataaccgc taccttatcc
    51301 gcaatacttg ccaccacacc aaggtcgtgg gtaataaaga ttgttgtgaa atgatactcg
    51361 ttttgtaaag attttagcaa atcaataatc tgagcttgaa tagttacatc caaggcagtt
    51421 gttggctcat cacagatcaa gacatcaggt cggcaggcaa gggcaatcgc aataacgata
    51481 cgttgacgca ttcctccaga atattggaat gggtattcat taaaacgtct atctgcgtct
    51541 ggaatgccaa ccttattcat gtagtcaatg gccaattctt tcgcttcttt agctgttttt
    51601 ccttggtgtt ttacaataac ttctgtaatc tgactaccaa ttgttttaat ggggtccaaa
    51661 ctagtcattg ggtcctggaa gatagtcgca atcttagcac cacgaatttg ttcccaatcc
    51721 ttgtgagaag ataaagctgt caagtcctga ccacggtagt caatactacc ttgggcaatg
    51781 cgaccatttt cttcgagcat acctgtgaag gtctttgtca aaacagattt acctgatcct
    51841 gactcaccta ccaaggctaa tacttctcct tcgactagtt caagggaaac gccgcgaatg
    51901 gctgtcaata ctttgtcacg aacgtcaaat tccacgacaa tatcgcgagc agtcaaaatt
    51961 acattttttt cttttgtcat ttctactcct atctatgtgt acgtggatca ctagcatccg
    52021 ctaagttttg accaactacg aaaagggaca aggataccaa gacaagggtt gtcaatggaa
    52081 tccagaacaa gtaagcattg gttgttacgt tttgtgaata atccgaaatc aaacgaccca
    52141 aacttggcac tgtaatcggt aatccaagac cgaagaaaga caagaaggct tcgtatgaga
    52201 taaagcttgg aagcatttga gtcatggttg tcacaataac agataccaat tgaggcatga
    52261 tatttttggc aacaatcttc aaggttggtg ttcccaaagt acgtgacgcc aagttgtatt
    52321 ccaagtcacg atagcgcaag atttgcacac ggatcatgaa ggcaatacca atccatgttg
    52381 ttacgctcat ggcaaaaatc agattccaga atccagctcc gattgagtaa gtcaagacaa
    52441 taacaatcaa aagaggtggg atgtttgaga tgacgttgta aacttccatc atgacacggt
    52501 caactgattt tgaaataccc caaataccac cgacaaaaac accgataacc aagttaatca
    52561 ctgtcgcaat cacagaaatg aggatggagt tacgagctcc gaaccagaca ccgtcaaaga
    52621 gcgatttacc gttactgtca gtaccgaacc aatgctccgc atttggcttg atataacgaa
    52681 cactaaagtc gtttaccttg ctgacatcat tgaaatcaaa cttagaaaac attgggtaga
    52741 tgaaacttat caaaatgatg gctaccaaga ttcccaacat gactacagtt gattttttct
    52801 tcataaattg tttaaacact gatttccagt aagaatatgc tggcgcatca atagtttcag
    52861 aggcaaaatc gtcacgtttt acaaactgaa atttttcttt atcgattgta gacattattt
    52921 gcctcctttc tcagtcaatt taatacgtgg gtcaataata gtcatccaaa tatctcccaa
    52981 aagacgtgag aagatagaaa tacatgtaaa gatgaagaca agaccaacga ccatagagtt
    53041 attagatgct tttacagagt caatcaacat tttacccata cctgggaagg cgaagactgt
    53101 ttcagtaagg gttgcaccac cgataacccc aataatggca ccaggaattc ctgaaaccag
    53161 cggaaccatg gcatttttaa agatgtgttt gtttgaaatt tctttttcag acaaaccttt
    53221 tgcacgagcg aaacgaacaa agtcttgaga ttgcaagtca atcatgtaac gacgaatcca
    53281 aatggctgta ccaggagcac ccaacaaacc aaggatgact gctggtaaaa cgtaagaacg
    53341 ccaatctcca gctcccaaga tagggaatga atctggaagg gaaatagatg atccaatcaa
    53401 tcgaacgatg taaaccaagg caatcgttgg aagagcaagc aagaaggtca aagcccctgt
    53461 tgagaggcta tcaatccaag tgttcttgaa acgagccatg gctgaaccaa gtggcacggc
    53521 aagagcatag gcaagaacca aaccaatcaa accagtaata gcagagctga caatcataga
    53581 tggatattgg taattacttt cagtcgctgt ataaggatca tctttcccat agctagctac
    53641 ttcacgagag tcagcctgac taggtgactt gtaggttctt gagtaaatat ttacagaaga
    53701 cgttttctta cctgttggga actgaacttg ggcagttttg gtttgtcctt gaccttgagt
    53761 aataacctga agaactggtg tattagcata ggttgggtaa gagtcaccta aattcaagtt
    53821 cacaaagttt tgatgaacaa atgggaactg actgttaaag tacaagagat atttatgttt
    53881 agttcctgaa ccgaccaatg accatccgat agctggatca ttttcaaaac gaaggtagcg
    53941 tttcaagtct ggattttcag ggtcttggat tttatttgta tggtcaatgt caatcaagtt
    54001 agcatagaag tgaaaaacac gttcaaaaat tggaatttca cgagtagcat agaattgacc
    54061 actttcagta aattctccca aagtccaacc atgacctaat tgattgatgt acttttcata
    54121 aatagcttta ttggtcgcat ttgcttctac tgttacagaa gaatccatgc tacttgcctt
    54181 ttcttgcaac tctttagtat cgtaatactc aatgtagccc atacgctcaa acacagtatt
    54241 ttcatagtta tcacgtttat cagccgttgt cgcaatttta ttatagttag gatcctgctt
    54301 gaaaatcaat tttcgaggaa ccaaggtata gataatcgtg taggtcaaag tcgttactaa
    54361 gaaaatcgaa accaatgacc gcaaaacacg cataaaaata tattttttca tattatttcc
    54421 tttaaaaatc ccaaaagaac cttctcctca tggagagaaa gttctattag aaattattta
    54481 cttcacatga cttgccaatt ctttttgagc tttctcattt gattcagctt tttctttcaa
    54541 ccatttttca cgagcttttt catactcttc cttagtcacc gctttatctt gtaatttcaa
    54601 atatttgaag taaacatctg accccttaga gcctgtttgc gcagaagctc cagtaaatgg
    54661 aacaattcgt gaaagcactg gtgctgcacc agaagaagcc atagcaggaa taaagagtga
    54721 actatctgtc aaccatgctt gagccgctgc atatttttca taacggacat tcaagtcgct
    54781 tgtctctttg gcagcttcat caactaattt atcgtattct ttcaaaccaa cttgaactac
    54841 tgaagggcta tttggattat caaatcctaa atatgttttt gtagtttcac tgctagttgt
    54901 ttttaaaata tccaggtaag tagatgggtc ttgatagtct ggcccccatg aaactcctcc
    54961 cgatacatcc caatcctcag atgaagcatt ggcagcatag taagtaatat taaggaattc
    55021 atcacttgtc atttgttgaa tatcaacaac gacattttca acaccaagaa ctgtttctac
    55081 agattgttta aaggactgaa tacgagatat atagtttttt gatgcttggt ctactggaac
    55141 gtccagatga ataggaaact gaacgccgtc tgcttctaaa gctttcttag ctttcgcaaa
    55201 ctctgccttg gccttgtcag cattgaataa accatcctgc ccatcagcta aattcacacc
    55261 tttccactca tcaccataag caggaagttg agcagcgact aaatcaccaa aggtcttctc
    55321 accagctgaa acaaagtctg gttttacaaa taaattacga actgctaaag ctgctccatc
    55381 tttaccattg atttgagctg agtaagctga gcgatcaaga gcaaaattca aggcttgacg
    55441 gaaatctttg ttaagcaatg ccttcttagt agctactttc tctgaatctg tagttttaga
    55501 agtatagttg taactttggc gatcaatatt cacacccaga ccagcaatcc cagagcctga
    55561 ttgtgtgtaa tagatattgt ccttgtattc ttctgcaacc ttagaatagt tggagctggt
    55621 agggtaaaga cgggcataac tataagctcc actagtgaag ttacgctcta gcgactcctg
    55681 atctgatcca tcatagtaag ctagattgat agtatctagg tggacatttt ctttatccca
    55741 atattgctca ttttttacaa actctacaga agattttgca gtcaaccctt tcaacaagaa
    55801 tggaccatta taaagcaagg atgtcggatc tgttggttta gcaaaatcgc ttccttttga
    55861 tgtttcgaat tcttcattca gaggccagaa aatagaatag gtcaacttag agttccagaa
    55921 cggttcaggc tggttcaaag tgtattgtaa cgtataatca tcaaccgcct tgacaccaac
    55981 tgttgaaaaa tctgttgaag ttcctgatag ataatctgcc aagcctttaa ccgaattttc
    56041 agctaaatac atagcttctg attttttatc tgctgcgtgt tttaaaccgt tcacgaaatc
    56101 tttagccgtc acctctgcat attcttctcc atcagaggta aaccatttaa cccctttacg
    56161 aatcttataa gtgtaggtca aaccatcctt agagacttcc caatcctctg caactgcagg
    56221 agcaagatta ccgtaattat cgttagtgaa taaaccatca atcccatttg aagtcactac
    56281 tgttgtacta tttttacttg aaatcaggta gtccaaggtt tctgggtctg ctgtataaac
    56341 atagccataa gctttagggg ctgatgaatc agatgatttt gaagaactgc atgctgcaag
    56401 tacacctgct gctaataaaa caagacctgc tgtagcaaat acacgatttt ttttcatttt
    56461 ctactcctct gtttatgtga attatagatt gacaaccatt atatcacatt atccattaaa
    56521 aatcaaacaa attttcagaa tatttaggct tgttggcaca aatttttcat tttttttgaa
    56581 tatatgattc aaattgtcgt tcgaagtgtc aaagactaca gtgaaaatag gaaatttgac
    56641 acagaaattt tggagcttag gaagacatac agtaaaatga aatacggacg gaacaatgtg
    56701 attttggaat tcaaattaaa ttataacaat attgtagaag tatcattcta gtattcaaga
    56761 ttcagtttac tatgtctttt cacaccaacc ttattccgaa ttcaattact ttcgtgattt
    56821 acacatatag attaagacta tcttttatac tttaaaattt ctcgctacct tgtccactat
    56881 atgctcctcg ctatcacgtt tctattcata gcctacgatt tcactattgc tttctctgac
    56941 aattcttatt tcctgcgtca gacttaaaac gatctatccc cagaccattt taatccgcta
    57001 cctcacgata gtcaggcttg gggagcgcta ttgtattcac cggtagtgga tccctacaga
    57061 ggacttacac ctcagatgca cgacatgccc atcgtataaa aaaatctcct acccaaggta
    57121 gaagatttca aacttataaa acttaatccg tcatgtccga taccaacatt cgatgctcca
    57181 atggaatact gcacataact agcaagaaaa taaagcctga ctgaatccag aagagagcca
    57241 agtcaaaaat tccgtgcaca gcaaccactg taaggaaaga tagataaagg ccgataatcg
    57301 gacgtttccc cgactcctga ctcatatcca tcatcaagcg aacaggagca acagaagaca
    57361 aaactaataa aatggtaccc acaattccgt aactcagaat cgtatcaata taaagactgt
    57421 gggcatgttc atgataagga gcatgtatcc gaggataaga gtgcatatag gtcaatggcc
    57481 cttcacccca aaaaggattt tgcttaaaca aggccatccc agcatcccag atagaaatgc
    57541 gttcttccat agaagagtct aaagtaccca ttcgaactcc caaatcacta gaaaagagga
    57601 aactcaaacc aatcgcgaag accccaatac taagccaaaa ggccttccag tttttaatag
    57661 tcgtaaagag atagataatt gctccagcga taatagcagg aaaggcagtt cgattttgag
    57721 taaagttcaa accaaagaga ttaacaaagc ctgcaatcac acagaatact ttcaaccaat
    57781 tcaacttggt cgttgtaaac agatagaaag caatcataat acagaaacaa caaataattc
    57841 cataataatt aggattaaag aaggtcactt ctgcccggtt ctgatgccac acctgcatat
    57901 tgggtgaaag aaaagcatag ttaaatttct tcacaatttg gaaatgttct aaactggcaa
    57961 aagcagctga caagacacta ccaaacaaga cgaactgcaa aatcaatcga aagaatttat
    58021 gggataaaat cgactgatag tgcaaaaaga aaatagtaaa tagaaacatt cctactgaag
    58081 ccacaagacc catccaattt tgtgcaagaa tggatataac agtactatag ctaagaaaaa
    58141 gaagcagcat cggatgctcc cccattttct gaagaatact tttcatgtct cctgtaaaaa
    58201 tcaaactgat aatatataaa cagagtacaa ctacaaaaag ataaaagggt aaaaagatac
    58261 ttaggataat tcccaataaa atcagctctt tactagacaa ccccttcagc ttttcaataa
    58321 agcctattga tttcaaaatg aatcctttct ctccaaatca gctgattcag ataatagtaa
    58381 gctatcctat attgtaccac ttttttagca atttgaaaac aaaggaaacg ttttccaaaa
    58441 taaaaaccct attttatcca ccatatcaag gcttcaaaat gatacttcaa ctccattctc
    58501 aattacccga taagtctgat tttgcaaatc aatttctact actgctgtta cggacttatc
    58561 tttattttga cgtttgatta caatgctgtg agctgttggt gtctctatct cagtagtccc
    58621 ttctagatca aaggcttctg aacggttacg gaaagaaaat agattgagaa gggccttcac
    58681 aacaggtcgt tgcacttctt ttgctatttc ctcgttgcta tagtaatgac gattaatatt
    58741 tcgaccttct ttagtttctt ctaataattt caagtcattc ttgcctgcta atagacccac
    58801 atagtaaacc tgaggaatac ctggggcaaa agcttgaatt agacgagcga gaaaatactt
    58861 gacatcatca tctccaagcg ctgaatagta ggttgaattg atttggtaga tatctaagtt
    58921 gttatactcg gcactagagt acttacgttt gacattggct ccaaccttat agagttcatt
    58981 tgaagcatag tcaatctcct catcggtcag gatatccttg acatctacta ctccaatccc
    59041 atcatgggta tctagcatcg taaattgctt catcgggctc atctttaacc acttagccaa
    59101 acgctctgtt ctggaactgt aaagagtata aagtgtcacc attggaagag caaaatcata
    59161 aacatagtaa tcatggtctg ctattttaaa ctgaatcgaa tagtgttcat gaatctcagg
    59221 taaaagctct gtcccatact cagcagcgat atctcgaact ttgtccaata aatcccaaat
    59281 atctggttcc acaaagaaat cattagtatc caatttcttc actgcataag caaaggcatc
    59341 tagacgaatc aaatcacacc cattacttgc caagtgctga atggtcttac ggataaattc
    59401 catagttact tctttggtca catcaagatc aatctgctcc tcaccaaagg tattccacaa
    59461 atgttccact gaaccatctt caaacacaat ctcttgcttt ggtgcacgat ccttacgctt
    59521 gtaaattaaa tctacatcag actgtgtcgg acggttttct ggccaaaact tatcccagtt
    59581 taaaaagaga gctttaaatt cactggcttc atgtttttct tgatagtcct tataatactt
    59641 ggattgacga gaaatatgat taatcataaa atcaaacata agataatatt tctcacctaa
    59701 acgcttaaca tcctcccaat caccaaaagc tgagtccact tcgtcgtagt caactggcgc
    59761 aaatccacga tcacctgttg atgggaaaaa tggtaaaagg tgaactcctc caatagcatc
    59821 tccaaaatgc tcttccaaat tatcatataa gtctttaaga ttatttccaa ggctatcaga
    59881 ataggtaatc aacatggttt tattttgaat tggcatcatt actctccttt ttctaattga
    59941 agccaagtct catatgatct ggcttcataa ataaaattca ttttaaatct ctatttatca
    60001 tcaaactcgt actaatatag actgtgataa acaaagtact actttcttgt tttctgcata
    60061 gaattatcaa caagctaaac tcttcctctg tgtcaaagac tatagattcc atgagctctt
    60121 cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta ctcaagtaca gcctgcggct
    60181 agcttcctag tttgctcttt gattttcatt gagtattact tcactgcccc gttgctcatt
    60241 cctgaaatga tatggcgttg gaagaagaga tagacaatgg tgatactgat aatgccgacc
    60301 acgtaagagg caaagcttgg tccgtagtcg ttgaaatatt ggcctgcgta gttgtattgg
    60361 aacaaaggca gagtccacat tttggaatcc cggttcaaga caaggagtgg caacatgaag
    60421 tcattccaga accaaagggc attgataatc atggttgtcg catgcatcgg tttcatcatt
    60481 gggaagatga tgcggaaata ggttgtaaat tgattagccc catcgatctc tgctgcttca
    60541 tccagacttt ctggaatcga gattttgata tagccaacat agagaaagag ggtctgtgga
    60601 atcgcatagg tcaagtagag caagatcaaa ccaaaggtat tagccaaacc gagtttactc
    60661 atcataaccg taatcggaat catgatgact tggaaaggta cgaagattcc gaggattaag
    60721 agggtataca tgatggtaaa ggcttttctt ttactcatat tgcgagcgat ggagtaggct
    60781 gccataggga taaagatcat tactgcaagt aaagacaaga cagtgatgac gacagagttc
    60841 caataatagc ctccaatccc atcagctaag agacggctaa agttgtccca tgtgaagttg
    60901 gttggaaagc caaagaaatt atctacaata tccttagtgg gtttgaagga actaaagagg
    60961 gtagcaagga gcggcactaa aatcagaacc gatcctagaa tcaatagaat gtatttgcca
    61021 atcagggctt ttctttcatc ttgtttcatc atgcttctcc tcttaaattt caaatttctt
    61081 agatactctc aattggatga tcgaaatcac tacaattaag aggaacaaga ttacggcaat
    61141 ggcattggca taaccgaatt ggttgttttt aaaggcatag ttataaacca agagcccaag
    61201 tgaggttgtg gcattgtttg gaccaccacc ggtcatggca aagacttggt caaaggcagt
    61261 cagcccacct tttagggcta ggataaagac catagagaca cttggtagca agtaaggcaa
    61321 ttcaatgttc cagaaaactt gcttgctagt cgcaccatca atccttgctg cctctgtaat
    61381 ctcagttgga atagattgca aaccagctag gaagatgatg atgggcatag ccaccccttg
    61441 ccaaagaagg acaaaggcag ccgcaaagat tgctccccac ttagtcccta aaagactggt
    61501 ttggagaaat tcaatatgaa gggcattccc aatcgctgga agaccgtagt tgaagacttg
    61561 cttgaagatc aaagccactg tcaaaccaga taaaacagct gggaagaaga accaagcacg
    61621 gaagaaggtt tggcctttga ttttagagtt caagacacgc gcaatgaaga tcccgagtgc
    61681 aatctcacca accaccatgg caatcgtaat gattgcggta aagccaatcg cattcatgaa
    61741 ttttggatcc atgaagagga gcttaaagtt gtttaagccg acaaatttgt agttataagt
    61801 caatcctgtc cagttggtaa aactgtaaaa ggctccttga aacatcggca catagaagaa
    61861 aattgcttgt aacaagaggg ggatgaccac aaaagcccat gcccaatatt tttgtaatac
    61921 ttttttcata gtctctctac tcctaatcca catccgcttt catcgggtta aagaaggcat
    61981 tcaaatcatt gaccatgcct tgtttatcac cggtcaagac atagttcatg gtcaaggtat
    62041 ggaagtctgc ttcactggtc cagtattgtt gcaaccagac caagtgacga tccgtaaagg
    62101 catattcggt cataccagca agcggtgaat cttctcctgc ttgtttgacc ccttcgatcg
    62161 ctgttggaga tccgtccaca tcgtagtatt tttgcatgac ttctggacgg gtcatatatt
    62221 ccacaaaggc attggcttct tttggatgtt tggtggtggc tgagatagac catgccaagt
    62281 ctcccgcacc aacggttaag ctttgtcctt tttcttttcc tggaatcatg aaggtcccaa
    62341 tcttaaagtt cggtttttgt tcattaatcg ctgtgatcgc ccaagaccca tttggtgtca
    62401 tgaggacatc cccacgtgcg aaggctccga taacatcggt atagccagca ccttcccagt
    62461 tcttttgctt agagccattg atgcgaagga tgtccatgac cttgatatca tctttcataa
    62521 tcggatccga caatttaatg gcatttggtt gagaataacg aaggtattga tttgcttctt
    62581 ttcctccacc tgttgctgtc gcaaaggcta attgattgta accattgagt gtccaagcat
    62641 ctgcacctgc aattccaaat ggtgtttgtc ctttagcaac gatatctttg actaactgtt
    62701 caaattcatc ccaggtttca ggaaccttca agcccagttc ttcgaattta tctttgttgt
    62761 agtaaattcc ataagcatta gctgtaaaag gaacgttgta aactttttcg tttacagcat
    62821 atttttcagc gtagccattt ttcacgcgtt tcaggtagtc tttgttgctc aaatcttcaa
    62881 aaacacctgc ttttgcccat tcttgcagtt cgatggactg tgggtaaata ttgaccacat
    62941 caggcacatc tcctgcgaga acgcgtgtct tcaatacttc accagcattt ggtacattga
    63001 cgactttgac cttgatctta gggttttcct tctcaaaatc acgagtgatt tcttccaagg
    63061 ttttggtcat ttcttttttc tggttgaaat actcgatggt cactgtgcca tccgcagatt
    63121 taccatagtt ggagcaagcg ccgagcccaa acaaagctaa acctgtagtt gcaagaagtc
    63181 cgattttttt ataccattcc attagaaagc ctcctttata aatttataca cccttattga
    63241 actgcacccc aaaagttaga cagaataaat ctaacttttg gggtcagtac atatcatagt
    63301 tttctaaaaa tatactgtct actcaaaaaa tctccttggg ataagataac agttaagccc
    63361 gcatacatta gttctgcacc tgagtaaact tcgccatttt cctgtaattt atatagtccc
    63421 tcttcatcca aatcttttaa ttttaaagtt gtttccatgg tctctacaac agataaaacg
    63481 cgaacgtagg ttacaatcgt ttgatttccg taattaaatt gtacagctgc ttcattggat
    63541 gcagtatcag gattaattag tctatactgc tgtcctaact gaactactgg tcgtaattct
    63601 ttatacaagt tcacctgatt agcaatcgta gctttctctt catctgataa atttgtcaaa
    63661 tcaagctcat agcccaaatt tcccatcatt gctacatggc cacgtgtttc taatggtgtc
    63721 attcgtccca tctgatgatt cggtactgct gacacatgag cccccataga aatggttgga
    63781 tagagatagg atgaaccgta ttgaattggt aaacgtgcaa tggcatcagt attatcacta
    63841 gcccagactt gtgggaaata gcgtatcata ccaagatcat ttcgtccacc accaccagag
    63901 caggactcaa agagaatatg gctgtgcttc tctgtcagat aagaaacgag ttcgtaaagt
    63961 cccagcatgt actgatgaga ttgcatctgt gtctctagat aagttaatcc attccctagc
    64021 ttagtgatat tgcggttcat atcccattta atgtaatcaa tctcatgata agataggagt
    64081 tgatctaaga cacttttcaa gtattctact acctgaggat tggcaagatt aagtactaat
    64141 tgattccgag aataagtatg ctcataatca ggaacctgaa tagcccagtc aggatgttga
    64201 cgatacaaat cactatctac agaaatcatt tcgggttcta accaaagtcc aaactgcaaa
    64261 cctctttcat ggatagctga aatcagactt tctagacttc cacccagttt ttcctcatta
    64321 acaacccaat cacctaaagc acgattatca tcaaaacgat tgccaaacca accatcatct
    64381 aatacaaaaa gttcaatgcc aactttctta gcttcatctg ctaactctaa cagtttttct
    64441 ctctgaaagt caaagtaagt agcttcccag ttattgatta gaattggacg ttctttttta
    64501 gaaaattcac ttagagtaat gtgcttcagt acaaaattct gactttcatg actaatacca
    64561 gttaatccct gatctgaatg agtcactaaa gctaccggtg tttcaaagta ttcctcaggg
    64621 gctaacttcc aagaaaagtt ttctggatta atgccaatag ccacccgaac ttcattcaat
    64681 tgattttttt gaacaaaagc ttcaaagttg ccactataca ttagttgaat agcaaacaca
    64741 ttcccagcat cctctgtgac tccttgttcg catagtagaa gagctggtgt ttgagcatga
    64801 ccagaagcac ctcggtttga actaatcgaa aagattcctt gttctacctg ttgacgtcta
    64861 acagtctttt cacgagcata agcaccctgc agagttacta tttcgtaatc tgcagctgga
    64921 aaatcagcca taaaagaaaa atctttatgg atgacaactt cctgattact attattatct
    64981 aatttactgt agctagcaat agtcgcatca ttattaaaag tagtataata caaagtcaga
    65041 ctaagttgag ccttagaatc ttctaacatt aagacaagag tctctgtatc gtccatgcta
    65101 tgtggagaag gtaagccctg tggaccattc tgacctttta aaatctttgc ttctacaaat
    65161 cgaaagtctg ttacttcagt tacactatgc tgaacctgta tagttggttt cctaaaatct
    65221 cctaagccat gttgtccaaa aatctgtcgc tgagtatcta aactaaaggt tcgattagta
    65281 gccgttggat ttcctgaaaa ggcatggtct cgttcataaa cactattgga acctttatag
    65341 ttcttaatag tctttcctaa atgtttcaaa agtaagtagc catttcgatt ttcaataatc
    65401 aaacttagat ttttactctc aacataaaat agattattct ctatcctaac tcccatttac
    65461 ttcacctcat cactttattg attatatttt atcacctgaa atcgctttcc aaaatagaaa
    65521 aatgtctcaa gaatatggta aaatgttagg taggaggtag cacatgctag ttttttcaga
    65581 ataccagact ggaacaattg accttgccct aagcttttat ggatatgagg aatgcacacc
    65641 taattactct tttggtccag ccattcgtga tacatacgtc ctacattaca ttagtaaagg
    65701 acaaggaaaa tttcattaca agggtaaaat tgttgattta aaagaaggag atttctttct
    65761 attaaaacca gaggaactaa ccttttatca agcagatagt aaagaacctt gggcctacta
    65821 ctggttagga atcactggag ggaaatcccc tgattatttt gctctttctc aaatttctga
    65881 tcaatcctat ctcatccaat ctgaaacttg tcatacccag actactgcaa aactcatctc
    65941 agacattgtc cgcttcgctc agattacaaa atcaagtgaa ttagctcaac tccatatcat
    66001 gggacaactt catgaactga tgtttcatct gggaactatt gctcccaatc agaaaaaaaa
    66061 gaatatttca tcaacccacc aactctatct tgaatgcaaa cgattaattg atagccacta
    66121 tcctcaatca cttacaattc aagatttagc aaaagaacta tccgttcaca gaagctactt
    66181 atcaagcgta ttcaaagaat ttaatacctt atcacccaaa gaatacctac tctacgttcg
    66241 aatgcaccga gctagacaac ttctcgaaaa tacccaagag tccatcaagg taattgcata
    66301 ctcggtaggt ttttcagatc cactccattt ttcgaaagct tataaacaat actttaatca
    66361 gtctccaagt catacaagaa aagaatactc tcaataccaa ctagtgagaa aggcaacatt
    66421 atgaaatcct accaagctgt ctaccaaatc ctatctaaag aaaccgacta tatcagcgga
    66481 gaaaaaatcg cagaaaaact atccctaagc cgaacatcaa tttggaaagc tatcaagcga
    66541 ctagaacaag aaggcattga aattaatagt atcaaaaata gaggatataa actaatgaat
    66601 ggtgacctta ttcttccaga gattctagaa gaaaatcttc caattaaagt cagctttaaa
    66661 cccgaaacaa aatcaacaca actagatgca aaagaagcaa ttgatttagg ccatgaagca
    66721 aatactctct atctagcttc ctatcaaaca gcaggccgag gccgttttca acgttccttc
    66781 tactcaccac aaggtggaat ttatatgaca ctccatctta aaccaaatct cccctatgac
    66841 aaattaccat cctacacact acttgtagct ggagctgtct acaaagccat taagaaccta
    66901 actttaatag atgtcgatat aaaatgggtc aatgatatct atctaaacaa tcataaaatt
    66961 ggaggaatcc ttactgaagc aatgacctct gtagaaactg gcttagtcac agatatcatt
    67021 attggagtag gtatcaattt cactattaaa gacttccctc aggaattaaa agaaaaagct
    67081 gccagcttat ttaaagctac agctcctata acaaggaatg aattgatcat agaaatctgg
    67141 cgtgctttct tcgaaacacc agcagaagag ctattatacc tatacaaaaa acagtcattc
    67201 attctaggaa aagaagtcac tttcacacta gagcaaaaag actacaaggg acttgctaaa
    67261 gacatctcag aaaatggaaa acttttagtt caatgtgata acggaaaaga aatctggcta
    67321 aatagtggcg aaatttctct caatagttgg aagtaaaata acacaattat aatataaacg
    67381 atataaaaat aacttcagat tagtaattca attaagtttt acggatctga agttttattg
    67441 tctctaaaaa caaaaaagag agttacaaac tctcattaaa acggagaata agggattcga
    67501 acccttgcgc cagttacccg acctaacgat ttagcaaacc gtcctcttca gcctcttgag
    67561 taattctcca attaatgggc acgagtggac tcgaaccacc gacctcacgc ttatcaggcg
    67621 tgcgctctaa ccacctgagc tacgcgccca agttaaaaaa cttggtaatt tgaacaaagt
    67681 tcaaagcggg tgacgagaat cgaactcgcg acaacagctt ggaaggctgt agttttacca
    67741 ctaaactaca cccgcataaa tactatcaat aaaatggcgc gagacggaat cgaaccgccg
    67801 acacatggag cttcaatcca ttgctctacc aactgagcta ccgagcctta ttgcgggagc
    67861 aggatttgaa cctacgacct tcgggttatg agcccgacga gctacctagc tgctccatcc
    67921 cgcgttaata taaaaggagg atgtgggatt cgaacccacg cacgctttta cacgcctgac
    67981 ggttttcaag accgttccct tcagccggac ttgggtaatc ctccaatatt caaatggacc
    68041 ttgtaggact tgaacctacg accactcggt tatgagccga gagctctaac cagctgagct
    68101 aaaggtccga caagatcatt atagcggcga aggggatcga acccccgacc tcccgggtat
    68161 gaaccggacg ctctagccag ctgagctaca ccgccatgaa tcgggaagac aggattcgaa
    68221 cctgcgacac cttggtccca aaccaagtac tctaccaagc tgagctactt cccgagttaa
    68281 aaagaaaaat gcaccctaga ggagtcgaac ctctaaccgc ctgattcgta gtcaggtact
    68341 ctatccagtt gagctaaggg tgctccatat tatgccgagg accggaatcg aaccggtacg
    68401 atcgttacca atcgcaggat tttaagtcct gtgcgtctgc cagttccgcc accccggcct
    68461 ctctaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt ggtgttctac
    68521 cactgaacta cgttcgcact gttttcttct atctaaaaat gccggctaca tgacttgaac
    68581 acgcgaccct ctgattacaa atcagatgct ctaccaactg agctaagccg gctcatttgt
    68641 tatatcttaa tgcgggttaa gggacttgaa cccccacgcc gttaagcgcc agatcctaaa
    68701 tctggtgcgt ctgccaattc cgccaaaccc gcatatatga cccgtactgg gctcgaacca
    68761 gtgacccatt gattaaaagt caattgctct accaactgag ctaacgagtc taaaataact
    68821 tgcgttatct taaacggtcc cgacgggaat cgaacccgcg atcttcgccg tgacagggcg
    68881 acgtgataac cgctacacta cgggacct
//
LOCUS       DBERAE010000006        65471 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.06, whole genome shotgun sequence.
ACCESSION   DBERAE010000006 DBERAE010000000
VERSION     DBERAE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 65471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.06"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..410)
                     /locus_tag="ACL70N_000498"
                     /pseudo
     CDS             complement(1..410)
                     /locus_tag="ACL70N_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(412..1449)
                     /locus_tag="ACL70N_000499"
     CDS             complement(412..1449)
                     /locus_tag="ACL70N_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGS0589351.1"
                     /translation="MNQTINYIKELTAIASPTGFTREISDYLVHTLEKLGYQPVRTAK
                     GGVNVTIKGQNDEQQRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPTQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1547..2872)
                     /gene="brnQ"
                     /locus_tag="ACL70N_000500"
     CDS             complement(1547..2872)
                     /gene="brnQ"
                     /locus_tag="ACL70N_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGS0589352.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAVAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3043..3330)
                     /locus_tag="ACL70N_000501"
                     /pseudo
     CDS             complement(3043..3330)
                     /locus_tag="ACL70N_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(3490..4068)
                     /locus_tag="ACL70N_000502"
     CDS             complement(3490..4068)
                     /locus_tag="ACL70N_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGS0589353.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFVAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMSKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4122..5522)
                     /gene="pepV"
                     /locus_tag="ACL70N_000503"
     CDS             complement(4122..5522)
                     /gene="pepV"
                     /locus_tag="ACL70N_000503"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGS0589354.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETCADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5535..6140)
                     /locus_tag="ACL70N_000504"
     CDS             complement(5535..6140)
                     /locus_tag="ACL70N_000504"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGS0589355.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6311..7111
                     /locus_tag="ACL70N_000505"
     CDS             6311..7111
                     /locus_tag="ACL70N_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589356.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7289..8122)
                     /locus_tag="ACL70N_000506"
     CDS             complement(7289..8122)
                     /locus_tag="ACL70N_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0589357.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(8112..9956)
                     /gene="uvrC"
                     /locus_tag="ACL70N_000507"
     CDS             complement(8112..9956)
                     /gene="uvrC"
                     /locus_tag="ACL70N_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGS0589358.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(9995..10696)
                     /locus_tag="ACL70N_000508"
     CDS             complement(9995..10696)
                     /locus_tag="ACL70N_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGS0589359.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(10775..12007)
                     /gene="murN"
                     /locus_tag="ACL70N_000509"
     CDS             complement(10775..12007)
                     /gene="murN"
                     /locus_tag="ACL70N_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGS0589360.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12012..13232)
                     /gene="murM"
                     /locus_tag="ACL70N_000510"
     CDS             complement(12012..13232)
                     /gene="murM"
                     /locus_tag="ACL70N_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGS0589361.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13344..14123)
                     /locus_tag="ACL70N_000511"
     CDS             complement(13344..14123)
                     /locus_tag="ACL70N_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0589362.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14192..15853)
                     /locus_tag="ACL70N_000512"
     CDS             complement(14192..15853)
                     /locus_tag="ACL70N_000512"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS0589363.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16028..18250)
                     /gene="recJ"
                     /locus_tag="ACL70N_000513"
     CDS             complement(16028..18250)
                     /gene="recJ"
                     /locus_tag="ACL70N_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGS0589364.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18527..19285
                     /locus_tag="ACL70N_000514"
     CDS             18527..19285
                     /locus_tag="ACL70N_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0589365.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            19325..20089
                     /locus_tag="ACL70N_000515"
     CDS             19325..20089
                     /locus_tag="ACL70N_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS0589366.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20102..20779
                     /locus_tag="ACL70N_000516"
     CDS             20102..20779
                     /locus_tag="ACL70N_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0589367.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20789..21448
                     /locus_tag="ACL70N_000517"
     CDS             20789..21448
                     /locus_tag="ACL70N_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0589368.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21706..22896
                     /locus_tag="ACL70N_000518"
     CDS             21706..22896
                     /locus_tag="ACL70N_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGS0589369.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(23217..24098)
                     /locus_tag="ACL70N_000519"
     CDS             complement(23217..24098)
                     /locus_tag="ACL70N_000519"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGS0589370.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24237..25565)
                     /gene="vncS"
                     /locus_tag="ACL70N_000520"
     CDS             complement(24237..25565)
                     /gene="vncS"
                     /locus_tag="ACL70N_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGS0589371.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25562..26218)
                     /gene="vncR"
                     /locus_tag="ACL70N_000521"
     CDS             complement(25562..26218)
                     /gene="vncR"
                     /locus_tag="ACL70N_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGS0589372.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26267..26350)
                     /gene="pep27"
                     /locus_tag="ACL70N_000522"
     CDS             complement(26267..26350)
                     /gene="pep27"
                     /locus_tag="ACL70N_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGS0589373.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(26530..27909)
                     /gene="vex3"
                     /locus_tag="ACL70N_000523"
     CDS             complement(26530..27909)
                     /gene="vex3"
                     /locus_tag="ACL70N_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGS0589374.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(27961..28608)
                     /gene="vex2"
                     /locus_tag="ACL70N_000524"
     CDS             complement(27961..28608)
                     /gene="vex2"
                     /locus_tag="ACL70N_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGS0589375.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28621..29898)
                     /locus_tag="ACL70N_000525"
     CDS             complement(28621..29898)
                     /locus_tag="ACL70N_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589376.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(30255..30425)
                     /locus_tag="ACL70N_000526"
                     /pseudo
     CDS             complement(30255..30425)
                     /locus_tag="ACL70N_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(30711..31166)
                     /locus_tag="ACL70N_000527"
     CDS             complement(30711..31166)
                     /locus_tag="ACL70N_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589377.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(31303..32187)
                     /locus_tag="ACL70N_000528"
     CDS             complement(31303..32187)
                     /locus_tag="ACL70N_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0589378.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(32191..32577)
                     /locus_tag="ACL70N_000529"
     CDS             complement(32191..32577)
                     /locus_tag="ACL70N_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGS0589379.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(32570..33913)
                     /gene="cysS"
                     /locus_tag="ACL70N_000530"
     CDS             complement(32570..33913)
                     /gene="cysS"
                     /locus_tag="ACL70N_000530"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGS0589380.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            complement(33995..34879)
                     /locus_tag="ACL70N_000531"
     CDS             complement(33995..34879)
                     /locus_tag="ACL70N_000531"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589381.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(34891..35508)
                     /gene="cysE"
                     /locus_tag="ACL70N_000532"
     CDS             complement(34891..35508)
                     /gene="cysE"
                     /locus_tag="ACL70N_000532"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGS0589382.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(35524..37737)
                     /gene="pnp"
                     /locus_tag="ACL70N_000533"
     CDS             complement(35524..37737)
                     /gene="pnp"
                     /locus_tag="ACL70N_000533"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGS0589383.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDYKPKKEFTETPKDSE"
     gene            37842..38114
                     /locus_tag="ACL70N_000534"
     CDS             37842..38114
                     /locus_tag="ACL70N_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine methyltransferase"
                     /protein_id="HGS0589384.1"
                     /translation="MKTRQFIFFTQLFGRVQLLKMLSRQATQRKIGNRTTERLLLGRF
                     IFFHRVVGVFSFQDTSLERFNIKVSKPFTLIAIGRLAKCFTNSFVK"
     gene            complement(38296..39162)
                     /gene="metF"
                     /locus_tag="ACL70N_000535"
     CDS             complement(38296..39162)
                     /gene="metF"
                     /locus_tag="ACL70N_000535"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGS0589385.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(39226..41475)
                     /gene="metE"
                     /locus_tag="ACL70N_000536"
     CDS             complement(39226..41475)
                     /gene="metE"
                     /locus_tag="ACL70N_000536"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGS0589386.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(41736..42002)
                     /locus_tag="ACL70N_000537"
     CDS             complement(41736..42002)
                     /locus_tag="ACL70N_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0589387.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(42128..42543)
                     /locus_tag="ACL70N_000538"
                     /pseudo
     CDS             complement(42128..42543)
                     /locus_tag="ACL70N_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            42699..43700
                     /locus_tag="ACL70N_000539"
     CDS             42699..43700
                     /locus_tag="ACL70N_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0589388.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(43768..46173)
                     /gene="pheT"
                     /locus_tag="ACL70N_000540"
     CDS             complement(43768..46173)
                     /gene="pheT"
                     /locus_tag="ACL70N_000540"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGS0589389.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(46250..46759)
                     /locus_tag="ACL70N_000541"
     CDS             complement(46250..46759)
                     /locus_tag="ACL70N_000541"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589390.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(46759..47805)
                     /gene="pheS"
                     /locus_tag="ACL70N_000542"
     CDS             complement(46759..47805)
                     /gene="pheS"
                     /locus_tag="ACL70N_000542"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGS0589391.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(48287..49702)
                     /locus_tag="ACL70N_000543"
     CDS             complement(48287..49702)
                     /locus_tag="ACL70N_000543"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS0589392.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(49715..51553)
                     /locus_tag="ACL70N_000544"
     CDS             complement(49715..51553)
                     /locus_tag="ACL70N_000544"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGS0589393.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(51571..52410)
                     /gene="licT"
                     /locus_tag="ACL70N_000545"
     CDS             complement(51571..52410)
                     /gene="licT"
                     /locus_tag="ACL70N_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGS0589394.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDFIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELAYLMAHIRRLTK
                     NLD"
     gene            complement(52710..54404)
                     /locus_tag="ACL70N_000546"
                     /pseudo
     CDS             complement(52710..54404)
                     /locus_tag="ACL70N_000546"
                     /inference="COORDINATES: protein motif:HMM:NF012403.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(54507..55492)
                     /locus_tag="ACL70N_000547"
                     /pseudo
     CDS             complement(54507..55492)
                     /locus_tag="ACL70N_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397831.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            complement(55595..55738)
                     /locus_tag="ACL70N_000548"
     CDS             complement(55595..55738)
                     /locus_tag="ACL70N_000548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589395.1"
                     /translation="MTGQRLNELEINGIRLTKFKNGEIGIEFIWIDTENPPSDAIGWV
                     AKK"
     gene            complement(55778..56533)
                     /locus_tag="ACL70N_000549"
     CDS             complement(55778..56533)
                     /locus_tag="ACL70N_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGS0589396.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            complement(56604..59255)
                     /locus_tag="ACL70N_000550"
     CDS             complement(56604..59255)
                     /locus_tag="ACL70N_000550"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGS0589397.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELDRLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(59267..60229)
                     /locus_tag="ACL70N_000551"
     CDS             complement(59267..60229)
                     /locus_tag="ACL70N_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HGS0589398.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(60231..60788)
                     /locus_tag="ACL70N_000552"
     CDS             complement(60231..60788)
                     /locus_tag="ACL70N_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0589399.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(60775..61353)
                     /locus_tag="ACL70N_000553"
                     /pseudo
     CDS             complement(60775..61353)
                     /locus_tag="ACL70N_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(61637..62032)
                     /locus_tag="ACL70N_000554"
     CDS             complement(61637..62032)
                     /locus_tag="ACL70N_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS0589400.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(62128..62382)
                     /locus_tag="ACL70N_000555"
     CDS             complement(62128..62382)
                     /locus_tag="ACL70N_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGS0589401.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(62392..63726)
                     /locus_tag="ACL70N_000556"
     CDS             complement(62392..63726)
                     /locus_tag="ACL70N_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGS0589402.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(63726..63959)
                     /locus_tag="ACL70N_000557"
     CDS             complement(63726..63959)
                     /locus_tag="ACL70N_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGS0589403.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            63990..64142
                     /locus_tag="ACL70N_000558"
     CDS             63990..64142
                     /locus_tag="ACL70N_000558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589404.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSSKHRFEVVDRTDEVS
                     NIYTAR"
     gene            complement(64407..64589)
                     /locus_tag="ACL70N_000559"
     CDS             complement(64407..64589)
                     /locus_tag="ACL70N_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589405.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(64591..65370)
                     /locus_tag="ACL70N_000560"
     CDS             complement(64591..65370)
                     /locus_tag="ACL70N_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589406.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQDPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT        18942 a        14726 c        11914 g        19889 t
ORIGIN      
        1 tctcatccgg ttttgcttgg cgggtttctg cggtcatttt ttcaaaaggg acccaccaga
       61 ctggcccaca gtccttgaga ccgtggccat tcatatcacc tcttcgtcta gggaaaaggt
      121 gccagtggag atgggcatcg ccatttccta gaagttcaat attcattttc tcagcagtaa
      181 agcccttggc aactgcctct tggactaaac tcatttcttc tagaaaatgg agtcttgtgt
      241 ccttttctaa aatggtgcaa ttccgtgaca tgttccttgg ctagaaagag actatagctt
      301 gcaaaatact gatggtctcc aatcacaaga tagcctgttc ccaactcttt gacaaagtag
      361 ggattttctc ccttcttgat gagctcaatt ctctggcaaa taaggcacat atcaatctac
      421 taaattgctt ctaagatagg catcgaccat tcgttctgtt gcgaccaccg agtcaatatg
      481 agtgcgctca taagaatgac tagactcgat acccgcacca agaagggcat gcttgacctc
      541 tgcccctgca gacatagccg ctgaagcatc cgaaccataa aatggataga tgtccagctt
      601 aaaaggaata tcttgctctt tagccaaggc aaccaagtgt tgacggaagt catagtgata
      661 aggacctgaa gcatccttga cacagataga tactgtgtac tcatctgtct gctggtcatc
      721 tcccattgcc cccatatcga cagctagata ttccaccact tgagttggaa tattggaatt
      781 agcaccgtgg cccacctctt cgaaaactga aaaagcaaaa tgagttgtta ctggcaattc
      841 aattccctct tccttataaa cacgaagaag attgagcaaa attgctgcgc tgaccttgtc
      901 atccaagtgg cgagacttga taaaaccagt ctctgtcaca acagttcgcg gatcgaaact
      961 aataaagtct ccaacctcaa tacccaaggc gcgcgtttct ttttcattgg ttacttttgc
     1021 gtccaaacgc acttccatat tgtcctgcgt acgttctgca gttcctgcat ccttgtagac
     1081 atgacaagaa gtctggtgga tgaggatggt cccagatacc gtttgacctg tgctagccac
     1141 atgaacggta cagttttctc cttcaatcat gttccaagga aaaccaccaa tacgatccaa
     1201 tttgagacgg ccatctggtt tgactgcacg aacaatagca cccagcgtat ccacatgggc
     1261 tgtcacatag cgttgttgtt catcattttg acctttaatg gtcacattga caccaccctt
     1321 agctgtacga acaggctggt aaccaagttt ctctaaagta tggactagat agtctgagat
     1381 ctcacgagta aagcccgttg gagatgcaat agcggttagt tctttgatat agtttatagt
     1441 ctgattcatt tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa
     1501 aagaaaatca ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa
     1561 aaacatcgct ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg
     1621 gcaccaacca tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa
     1681 actcaacctt aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa
     1741 ttgtcaactg catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa
     1801 cgatagcaat cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg
     1861 catcaagacc caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct
     1921 tgtagctgat ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa
     1981 cagtcgttgt gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc
     2041 caaagatttc ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg
     2101 cttcagctgg tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga
     2161 aggcaagggc aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg
     2221 aaaatccaag ttgtttcaag gtttgaactg cgattacgct aaaggccact gaggcaaggg
     2281 cgtccaaggt attataacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag
     2341 ctgaagcagc ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa
     2401 caatcaaaat tgcaaagact ggcgttaaaa tacgtccaat gcggtctaag atttttgatg
     2461 gattaagcga aatcaaatag gctaccgcaa aatacagaac cgtaaataca atcaagccaa
     2521 gtcctttatt tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag
     2581 tacgtggggt agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg
     2641 caaaccaagg cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc
     2701 caataataag ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag
     2761 gaagaaaatg ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac
     2821 caaaaaatat tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct
     2881 ccttcatatt tataaaatac tgacctagta taccacgatt aggagtctga aaaaagcatc
     2941 acgaggcaaa tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaacaaaa
     3001 ctctcctacc cagtccacac caagtaggag aaatgcaaaa ttttaaagtt cttcaaaggc
     3061 taacatgcca ccctggacat tgataacatt ataaccttgt tctaacagga attggcaagc
     3121 acgcgccgat ctcattccag atttgcaaat aatataatgc aagcgatctt tgtccaatta
     3181 atcataacta tcagccaatt gactaagcgg taggttgtgg gtaccttcta aatgaagagc
     3241 tgcaagctca tccacttctc tcacatccac tagagaaagc tggtcgtttt ggtaaagctg
     3301 ataaaatgcg tcaaaggcta tttctttcat tctttttctt ctaatactct tcgaaaatct
     3361 cttcaaacca cgtcagcgtc gccttaccgt gcgtatgtta ccgacttcgt cagttttatc
     3421 tgcaacttca aagctgtact ttgagcagcc tacgactagc ttcctagttt gctctttgat
     3481 tttcattgac tataaaatgg ttttaattct ttttttcaaa tctggcacta cttctgcctc
     3541 aaaccaagga tttttggaca tccagatttg atttcgtggt gatgggtgaa ctagcggaaa
     3601 ataggctggc agatagtctt tatagtgttt caccctctcc gttaccttcc cactgatttt
     3661 ctcctgtaaa tagtaggctt gggcatattg cccaatcaag agggttaact gaatatcagg
     3721 caattcctgt aagagctgcg gatgccattt ttctgcaaaa tctgtacgag gcggaagatc
     3781 acccgacttg ccatgtcctg gaaagtagaa atccataggc aaaacagcaa aataacctga
     3841 attgtaaaag gtatcttcat ccacacctag ccagtcccgc aagcggtcac cacttttatc
     3901 tttccagtaa aggcctgctt cttgagtttt aagtcccgga gcctgaccga tgatattgat
     3961 gcgagcagtt tttggcgcta caaagagagg ctcaatgcca cgctctgtat agctggcatt
     4021 ctgcgaatcc gccatgatag cctgtttgat tctttcgatt tgagacatct actttccctc
     4081 caaaaagaag tccaagcata agatctcaga cttctatcgt tttatttgat caattcgtaa
     4141 atagcttcgg cataaattgc tgctgctcgg aagagatcgt ccaaggcaat aaattcattg
     4201 gcttggtgca tagtatcaat tgagtctggg aacatagcac cataggcaac tccgcgctct
     4261 aacaagcgac caaaggttcc accaccgatg acttgttcat gaccttgtag gcctgtttgt
     4321 ttttcataga cattcaacaa ggtttgcaca agtggatctt ccattggcac atagtgaggg
     4381 gtatgaccat gttctgatag actgacagaa gcaactggca agttttctag gattgacttg
     4441 atttgttctg gacttgttcc ttttggatag cggatgttga gggcaatggt attatcagca
     4501 catgtttcat cgaagcggaa gacgcctgca ttcatagaaa gggcacccat cttttcatcc
     4561 acatgagcaa tcttgagact ttcaccctca tggtcgttca agagaatttt accagtgatg
     4621 tcaaggtatt ctttggctgg accagcaaag tcaaactggc taaggaagag ggctaggtaa
     4681 gtcgcaccat tgacacctga agcaggcata gcaccgtggg ctgatttacc aatgatcgtc
     4741 accttgtatt tgccagcttc ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag
     4801 gcatctagtt tagcttgcaa gtcagccaaa tcacctgaaa cgactgctgt tgctgattct
     4861 ggtaccatat tttcacgtaa accacctgta aagctgtgaa gacgggcagc acctgtattt
     4921 tctcctgcaa agtggaggta ttccgtgata tttccttttt caccattgat gatagggaat
     4981 tcagcgtctg gagagaaacc gaaatctggt ttggcaagtc ctacgtgctc aaagtagtag
     5041 tccatatctg cccagcctga ttcttcgtct gttccaacga tgaagcgaac tttcttagaa
     5101 gttggaagac ccaattcttt gatgattttc aaaccatagt aacaagctgt tgtaggaccc
     5161 ttatcgtccg aagccccgcg cgcataaagg cgaccatctt tgatagttgg tgtgtaagga
     5221 tctgtatccc aaccgctacc agctggaacc acgtccatat gggcaaagat tccgagaact
     5281 tcttctccat caccaaactc aaaatgtcct gcatagttat caacattttt agttggataa
     5341 ccatcacggt ctgcgatttc aaggaatttt tccaaggctt ttactggacc aggtccaaat
     5401 ggatgttggg catcagcctt gctatcatca cgttctgagt tgatttccaa aaggctaaac
     5461 aagtcagcca agaggtcttc tttgcgtttt tctacttctg ctgtaaaatc aattgctatc
     5521 attttttctt cttcctatct tttttcgatg atttcatcta ctggcaagcg gtagcttggt
     5581 tccaatttgt cgtctgtgta acccactgtg atcaagagtt ctgggcggaa acggtcttcg
     5641 atttccaaaa cttcattaac ttttgatttg tcaaaaccaa ggataatatt ggaaccaatt
     5701 ccttggtctg taagagcgag aaccaagttc atagcaacca aacctgcatt gagtgctagg
     5761 tagtcgctga cttgttgttc attgtagcgt gcaaattcag ctggcaaatt tttcatgaag
     5821 tattgaagtt gttcttctga gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg
     5881 cgtttggcaa ggtctgtatc tgtaaatagg gcaatggtta caggtgctga tgatacctgt
     5941 tcaaaattgg aaccataagc taactttgcc agttcagcat ttttctcaca taccaccaca
     6001 aatttccaag gctggctgtt gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta
     6061 cgcacatctt ttggatcaac aggcttatca gtgaaatgct tggtcgcatg acgtttttta
     6121 tttaattcaa gaaatttcat aatcgatttc cttttctaat tctactgctt ccattctacc
     6181 ataatttgaa agagcttgca gggatttttc atgattaagt ttttctatca cagacataaa
     6241 agatatatat tggtttatca ggaaagtttc tgataaacta gcaagtactt tacatttgaa
     6301 tggagacagt atgaaaaaat ttagcctatt actagctatc ctaccatttt tggttgcctg
     6361 tgggaatcaa gctacaccca aagagtccag ctctcaaaag acaatcgtcc ttgctacagc
     6421 tggcgatgtg ccaccatttg actacgaaga caagggcaat ctgacaggct tcgatatcga
     6481 agtcctaaaa gcagtggatg aaaaactcag cgattacgag attcaattcc aaagaactgc
     6541 ttgggagagc atcttcccag gacttgattc tggtcactat caagcagcag ctaataattt
     6601 gagttacaca aaagagcgcg ctgaaaaata cctctactcg cttccaattt ccaacaatcc
     6661 cctcgtcctt gtcagcaaca agaaaaatcc tttgacttat cttgaccaga tcgctggtaa
     6721 aacaacacaa gaggataccg gaacttctaa cgctcaattc atcaataact ggaatcagaa
     6781 acacactgat aatcccgcta caattgattt ttctggtgag gatattggta aacgaatcct
     6841 agaccttgct aacggagagt ttgatttcct agtttttgac aaggtatccg ttcaaaagat
     6901 tatcaaggac cgtggtttag acctctcagt cgttgattta ccttctacag atagccccag
     6961 caactatatc gttttctcaa gtgaccaaaa agagtttaaa gagaaatttg ataaagcgct
     7021 caaagaactc tatcaagacg gaacccttga aaaactcagc aatacctatc taggtggttc
     7081 ttacctccca gatcaatctc agttacaata acactcttcg aaaatctctt caaaccacgt
     7141 cagctttatc tgcaacctca aagctgtgct ttgagcaacc tacggctagc ttcctagttt
     7201 gctctttgat tttcattgag tataagatat ataaaagcga ttggactacc aatcgttttt
     7261 agtttgcatt ggttatttta ggaaactctt acaaaaaatc aaaaaaattc ttcacatcct
     7321 ctacatacct atgcttttct attaagcttg ctaatagttt cagattgtgc ctctgatagt
     7381 tatcttcacg acgtagttct tcatacattt cgataaaggg aagccccttg gatttggcca
     7441 attctaactc agcctcgtaa tcataagcaa ctttacgaaa ttggatattg agtaattccc
     7501 catcttcaac ctctatcacg gcatactggg cacggtgatt ttttaacgcc tcccaattaa
     7561 aatagggcat gccaatcgac cctggattga tgatttgttg ccctttactg ccgtagcgaa
     7621 gcaactgctt gtgaacatga ccataaactg ccacgtccgt ttccgcatct agcagttggt
     7681 caaatttctc tgtatcattc tcaactagca agtcaccacc atagtttttg tcaggtaaat
     7741 tatgagagat agaaaagcgc aatccgtcaa tttctttctt ttccagcaaa ggcaagcttc
     7801 gtagccagac aatcgttgca ggatccattc gctccatcaa aaactgggtc atgcgcattg
     7861 actggatttc tttcggatat tccaaaccat attcgccatc caagacctca aggacacgat
     7921 catcccaatt gcctcgaaca cttgctgtga taggaaggtc ctttagcagg gcgactaagt
     7981 catttgcgcc tggaccagga agaaaaatat ctccctgaag ccaatattca ctggcccctt
     8041 gatttttagc atctgcaatc actgcttcta gcgccgtcgc attgccatga acatctgata
     8101 aaattgcgat tttatggttc attgtggttt ccttccgttt ggtaatctac tctttcttct
     8161 gctacttgag gcaaggcttc tccctgcggg ttcaactttc tttgcacagc ctctgcaacg
     8221 actctaggta ccccaacttc gacaatctca tccacactgg cttccttgat tttggtcaaa
     8281 gacttgaaat gcttcataag attctgcttg cgtttaggtc ccagaccgtc aatcccatcc
     8341 aattgagatg agaaagaatt tttggagcgc agttggcggt ggaaagtgat agcaaagcgg
     8401 tgcacctcat cttggatgcg ttggaggagg aaaaattcct gagaattgcg agacaagtcc
     8461 accacctcaa gcggatctcc aaagagcaat tcatgggttt ggtgcttatc attcttttgc
     8521 agcccagcaa ttggaatatc caagcccagt tcctcttgga tgacttgctt agcaatattg
     8581 acttgacctt gccccccatc aatcacaatc aaatctggag gagtcaaagc ctcacgctgt
     8641 actcgaccat agcgtctgcg aatgacttct ctcatactag catagtcgtc cggcccaaca
     8701 acggttttta tcttgtactt acggtaatct tttttacttg gcctgccgtt aacaaagacc
     8761 accatggctg aaacaggact ggtccccatg atgttggagt tatcgaagga ctcgatgcga
     8821 actggagtcg gaatttggag caaacgtcct agattttcaa tagctccttg ggtcttttcg
     8881 actgattttt ctagcagatt gaacttctgc tctagactaa cacgagcatt ttttatggct
     8941 agattgacca gctgtttttt ctctccacgt tggggtttga gaatcttggt atccaccaaa
     9001 gccttgacag cttcttcgtc aatatcctgc ggaatcagta cctcattggg aactaggtga
     9061 gatttttctt gatagaattg tcccacatag gtcaagaaat cctcatctgg atcattgaag
     9121 taggggaaga gattgacatc gcgctcgatg agcttgccct gacgaacaaa gaaaacctgc
     9181 acacacatcc agcccttatc cacatagtag ccaaagacat cgcgattttg gagatcctta
     9241 gccatgaccc gttgcttggt tcgaagtgtt ccaatggcct gaatcaggtc acggtattcc
     9301 gctgcccgtt caaactccat actttgtgct gttactgcca ttttactctt gagatcatcg
     9361 atgattttgt catcctgacc tttcagaaaa tcagacacct cctgggccat ggacttgaaa
     9421 taggcctcgt cattcttaca gatggtgtgg gccatacatt ggccgatatg gtagtaaaaa
     9481 cagaccttag agggcgggtt ggtacatttt cgaaaaggga aaatcctatc tagaagtcgc
     9541 ttgatttcat tggctgcccc cacatctgga taagggccaa aataaagacc accgtccttt
     9601 ttgacctgac gagtaatgat aagccgtgga tagtgctcat tggtgatttt gataaaagga
     9661 taagacttgt catccttgag catgatattg tacttgggct tattttcctt gatcaggttg
     9721 atttccagca gaagcgcctc aatattagac tccgtaacaa taaattcaaa atccacaatt
     9781 tcagacacca aggcctctgt tttggtatca tgacttccac ggaaataaga cctcacgcga
     9841 ttacgcagat ttttagcctt tcctacatag ataatggtgc cgtttttatc cttgtaaatg
     9901 tagcaaccag ggctggtcgg caagagctct agttttggtt taatcaagtt gttcatagtt
     9961 ccattatagc aaaaaagtag ggaaagatag taccctactc attagtctca tatatttttc
    10021 ggaggtttgc aacatcctct tcctggatac cataaaagga acctgctggt tgcatgacag
    10081 acttctcatc tgtatggtcc aagccaatcg catgacctaa ctcatgttct gccgtatgga
    10141 caaggcgttc ataggaatag ccatagtatg gattggacaa ataataatga ttcaaccgca
    10201 ccgttacgga caagaattgc cctgttaaga gattagtttg actttccgcc tctcctgcca
    10261 caggagtgcc tccgtcgttc atctccgtag ccgtaatatc cgccttacta gactcagtca
    10321 cgagttcaaa gttaaaagca ccagtttgat tccagttctg gattgcttct aaataagcct
    10381 cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg agcagaggcc tgtggccacc
    10441 ttccttcaga atgctggtga ctatctgtct ggcttaactt aggcagttgc cctgttttct
    10501 cccattggtc aatactttgt tgaccaattt ttactgaccg ttctgcttgc tttagcgctc
    10561 cttgaaaatc cccgttcaga taccagagaa gtccgaaagc aagcacacat aagagcacaa
    10621 ctatccaaac cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac
    10681 gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata aaaattattt tactaaaaga
    10741 agctaaaaga aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta
    10801 actggatagc tttgtatttt aaaggagatg gatggtaacg gaaagtacct gctttgcgta
    10861 caatatagcc attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc
    10921 cttgaatgcc taggaagttg tatttaggta ttccacgttt tatgctttcc aacataacat
    10981 atttttgaag cagtgcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga
    11041 gataagtcgt ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt
    11101 ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt
    11161 gactagaata ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat
    11221 caagtcgcaa cttgtccaag ttttcttcta gtttattttg ttcaccttgc aatttgctca
    11281 tatagtccga aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat
    11341 aaaaatgctc ataatattct aaacttttat cactatattc tctacgttca gaggtttctt
    11401 ttgttatatt cttaaaaatc gatagttctt cacgttttaa ctttttcaat cgaatgccaa
    11461 aggtttcagc ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct
    11521 tttcagttaa ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac
    11581 ctgttgttaa gccatcaaat tgataaccta aatcagtcaa accttgaata atactttttt
    11641 tctcagcatc tattggatta ccttggctat caaaagtttg ataagtttca taaggtttta
    11701 caagcaactc taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg
    11761 gaagagcatc ttgttgggta taaatcggcc ccgaattgag ttccatatgc agaccaccca
    11821 gcatgggcaa gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa
    11881 gataaacaat tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa
    11941 aggaacgaga agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta
    12001 gtgccatata cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt
    12061 cttaacagag gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc
    12121 gttggattaa atttttcctt aaaatgataa agtccaccat tgagagagtt ttcaacacca
    12181 cctaaatttt gccagaccat acctcgctca aaggcatagc gagccgtttc ataccatgtt
    12241 aaaattggtg cattgtaacg tttaaaatca tcatccatac cagcatatat attgacagag
    12301 gtagtaccaa attccaaact caaagtagcc gctaaaggaa ctctcgcttg acctacatct
    12361 atatattcct gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct
    12421 tctacttttg aagttcgagt cgactcagta aaggtctctt ccaaggctct atttttcgct
    12481 aactgttctt ctaattcttg cgaacgttta gaaacatcca aggtggccaa ggtgatatag
    12541 gccttgtcct taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc
    12601 tcttttcgct tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca
    12661 ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa tagcctgttt tgttgacttg
    12721 gaaagtttat cttcttcaaa attttccttg tatattttcg cctgaatacg aggttgaatg
    12781 gtgtctccca tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca
    12841 ataatagcca gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg
    12901 caaatacttg ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata
    12961 gactgaatgg caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg
    13021 atgtaaaaca ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt
    13081 aatttttctt ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc
    13141 caagcactac tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct
    13201 aatgtgggaa tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta
    13261 ttactattct actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta
    13321 ctccccctat gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt
    13381 agggttgtta aaaaaacttc caattgtttt tcccagtagt accactcgtg agttccagca
    13441 ctatggctat aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg
    13501 gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat
    13561 tttttagcca gactttcaag agaataggga ctagttgtcc agtctctaat ctctccaaaa
    13621 acacctctcc agtaggctgg acttcccaga ttttgacttt caggagaaaa gttttgaaag
    13681 ctgagggcac ctgaaaaact agctgcatga gaaaaacgat ttgtcgtaag agccagtttg
    13741 aagcagccgt agcctcccat agaaagacca gcgataaagg tcttttcacg cttgctagtc
    13801 atattaggga agaagcgttt cagaacctgc ggcaattcct ctgctagagc cgtgtagtag
    13861 tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg
    13921 agattagttc ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt
    13981 ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact
    14041 cgattggcat cagggtagag gacattcacc ccccactcca tatccaatac ttgtgagtaa
    14101 tactcgattt tcattactgc catgattttc tccttctatt tttctataag aaaaagccga
    14161 aactcgactt tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa
    14221 tagctggacg acgcttggtt tggtcaaaga gatacttggt caaattatct cgaaccttcc
    14281 ctttaagatc tgcccagtca aagtcatctc cttgaagata atcttctacc gtttggttaa
    14341 tcaattctga actttcacgg agaatatcgc gactcttctt gagataaaca aatccacgcg
    14401 tgtgaacacg agccctagcc acaattttct tctcacgacg gttgactgta atagccacga
    14461 tgaaaattcc atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac
    14521 caatggcatt cccatcaatc aagatatctc ctgctgaaac cgatccagct ggaacaaagt
    14581 ctccattctc gtaagccatg gtcgtcccct ttttaggaat gaaaatgcgt tctggcaaca
    14641 tcccaactgc catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag
    14701 ggaagaggta cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt
    14761 gccctgatac atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca
    14821 tattttccac acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga
    14881 ccaggtcccc atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc
    14941 cattgatagg ttcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc
    15001 gagacatatc tttaggctta atcaagagaa tttcgttggc taaagacaac ttcttaagac
    15061 gaatcgctgt gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg
    15121 ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa
    15181 cgatgatacg accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt
    15241 cactagccac ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc
    15301 cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt
    15361 ggtcaaattt gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc
    15421 ccagactctc tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat
    15481 caatctccgt attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc
    15541 ctttgacaaa gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag
    15601 cctctgccaa gagataaggt agagcaccaa tggcatccgc atgcccgtgg gtcaagaaaa
    15661 ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga
    15721 cccctaattg ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc
    15781 caatttcagc aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac
    15841 tgatattact catttttcct ccaaaatctt agtttatctt gattataggg caattctacc
    15901 ctcttattct aaaagttctg atactttcag ccgaatcttt tcctaccatt ataccatttt
    15961 tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc
    16021 ctaacttcta ctctttttcc atcaaaaaat cataaatttc ttgcaccgta cccagcgcca
    16081 tcatttcttg gtctttaacg gtttgtttga gattttggta aatttgactt tctcctatct
    16141 cccgctttgg cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta
    16201 gttcttcaaa tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag
    16261 ccaaatcttt cagcttgtag cgaatatcaa actctgggaa ctggtaaata gtcttgtaca
    16321 atttagcaaa ctgatctcta gtcccataac ctgtcagata ataggtcttg tcaatatcat
    16381 ttttgaaata gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat
    16441 cctctggaat gttttttacg acaacagctt cactagccgc aagatttggc agttctccag
    16501 gaaaatccaa gactggaaca ccttctggca agactgcatt ttttccacga atgttaaaaa
    16561 gttgaacacc ttccactcgc gcatccacca tcatcaactg gagggcagtt tggccattcc
    16621 attggttgac agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg
    16681 cccatctgcc ttgaccaaag gctaccactt caaaactcgc ctcacccttg gaaattttca
    16741 gctttagatg ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga
    16801 tataaaaaat aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga
    16861 ccgtttccaa gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc
    16921 caccagcatc tgcacctttt tcacgaacat aatcttccaa aacctgagat aaatctgaga
    16981 gttgctcaac ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgatgaaga
    17041 ggtctcgatg gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc
    17101 ccttggcacg accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata
    17161 aacgaccagc cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa
    17221 ccttcttctc aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct
    17281 tgcgctcttc gtttttctgg tgaatcataa gggcaatctc atgcgcttcc tcatcatcaa
    17341 atccagtcaa caaatcaatg gcaggattgg gatcatccaa gcgacccaag gcattcaaac
    17401 gaggagcaat ctggaaacca accgtttctt ctgttacttc gttggcagca atcccagcca
    17461 tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc caacatttcc agaccatatt
    17521 gaactaagat acgattttca tccgtcagac tcaccatatc tgcaatagtt ccaatagcga
    17581 ccaaatcaag caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa
    17641 ctccacaacc agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa
    17701 tagcataagc atctggcagg gtttcaggca tggaatgatg gtctgtcaca atgacatcta
    17761 ctcccataga ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca
    17821 caatcaagga aattccttct tgctcgataa agtatttata aacactagca ttagggccat
    17881 agccatcggt aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt tgttccaaac
    17941 tttccttcac aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa
    18001 tattttcccc ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga
    18061 gcagataagc atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt
    18121 ggtcctgaat ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct
    18181 tggctatctt tgtaaaatcc gcatcttcta cctgcagggc aaactgccat tcataagtag
    18241 gtgttatcaa aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt
    18301 tagacgtttt ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga
    18361 atagtacacc tctacttcta aaatattgtt agaaatcgat ttgactgtcc cgatcgattt
    18421 ttcctgttct tatttcacta tagtgaattt tttcagatat gatttgacaa gaacattctt
    18481 ttattgcaga atcgtgttat aaaatctaac ataaaggagt tctctcatgg ttttagtaga
    18541 atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg
    18601 ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct ggctctggga agtccactct
    18661 tatccgtacg atcaatggtt tagaggctgt tgacaaagga agtctcctag tcaatgggca
    18721 ccaagttgct ggtgccagcc agaaagattt ggtacctctt cgcaaggaag tcggcatggt
    18781 ttttcaacat tttaaccttt atccacacaa aacagtgtta gaaaacgtga cacttgcgcc
    18841 cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa accgccaaaa aatatctgga
    18901 atttgtaaat atgtgggaca agaaagattc ctatcccgcc atgctatctg gtggacaaaa
    18961 acagcggatc gccatcgctc gtggtcttgc tatgcatccg gaactcctcc tctttgatga
    19021 accaacatct gctcttgatc ctgagactat cggagatgtt ctagcagtta tgcagaaact
    19081 ggcgcgtgat aggatgaaca tgatcatcgt tacccacgaa atgggctttg ctcgagaggt
    19141 tgcggaccgc attatcttta tggccgacgg agaagtttta gtagatacga cagatgtcga
    19201 taactttttt gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca aaattatcaa
    19261 ccacgaaagt gacaaagtca aataaggagg cgcctatgaa aaaaaattct ttttatcagc
    19321 attattgatt agccttttcg gccttgctgc tgccaaacca gtccaggctg atacaagtat
    19381 cgcagacatt caaaaaagag gcgaactggt tgtcggtgtc aaacaagacg ttcccaattt
    19441 tggttacaaa gatcccaaga ccggtactta ttctggtatc gaaaccgact tggccaagat
    19501 ggtagctgat gaactcaagg tcaagattcg ctatgtgccg gttacagcac aaacccgcgg
    19561 cccccttcta gacaatgaac aggtcgatat ggatatcgcg acctttacca tcacggacga
    19621 acgcaaaaaa ctctacaact ttaccagtcc ctactacaca gacgcttctg gatttttggt
    19681 caataaatct gccaaaatca aaaagattga ggacctaaac ggcaaaacca tcggagtcgc
    19741 ccaaggttct atcacccaac gcctaattac tgaactgggt aaaaagaaag gtctgaagtt
    19801 taaattcgtc gaacttggtt cctacccaga attgattact tccctgcacg ctcatcgtat
    19861 cgatgccttt tccgttgacc gctctattct atctggctac actaataaac ggacagcact
    19921 actagatgat agtttcaagc catctgacta cggtattgtt accaagaaat caaatacaga
    19981 gctcaacgac tatcttgata acttggttac taaatggagc aaggatggta gtttgcagaa
    20041 actttatgac cgttacaagc tcaaaccatc tagtcatacc gcagattaag gaggataccc
    20101 tatgacagat ttatcatctt ggacagccta ttttcaggat tttggacaat ttttcaatgg
    20161 tttcctcttt actcttgccc tagcgattgg atcctttatc ctcgccatgg tcttaggaat
    20221 cttctttggt gccatgtcaa ccagtaaacg tccaatttta cgcattttag ctcgcatctt
    20281 tgtggaattt taccaaaata ctcctctctt ggtgcagttt gttattgttt tttatggcct
    20341 acctcttatc agtgaccata tcatcatgat tccaatttat tggacagccg ttctctgcgt
    20401 gggactctat cacggcgctt atatcgctga ggttattcgt tcagggattc agtctattcc
    20461 tagtggtcag atggaggccg ccttgtcgca aggttttacc tatatcagtg ccatgcgctt
    20521 gattaccttg cctcagacct tccgcatcat tctccctcca ttgaccaacc aaattgttaa
    20581 cctcatcaag aacacctcta ctgtagctat catctctgga gtagacttga tgtttgtgac
    20641 taagtcttgg tcggctctca acggaaacta tatcccagcc tttttaggtg ctactcttct
    20701 ctactttgcc ctatgcttcc ctgttgccca gtttggtcgc aagatggagc aagccaacaa
    20761 aaaagcctat tcactttagg aggttactat ggaatctatt ttagaagttt taaccccaga
    20821 taacctagtc tttatcttta aaggatttgg cttgaccctc tatatttctc tgattgccat
    20881 catcctctct actatcatcg gtacggtgct agctgtcatg agaaatggca aaaatcctgt
    20941 cttgcgaatc atctccagca tttatatcga atttgtgcgc aacgttccca accttctctg
    21001 gatttttact atctttttgg tgttcaaaat gaaatccaca ccagcaggta ttacagcctt
    21061 tactctcttt acatcagcag ccttggctga gattattcga ggcggtctca atgccgtaga
    21121 caagggacaa tacgaagcag gaatgtcaca aggcttcacc tcagcccaaa tcctctacta
    21181 catcattctc ccacaagcca tccgcaaaat gctaccagcc atcatttctc agtttgttac
    21241 cgtgattaag gataccagcc tcctctactc tgttatcgcc ctacaagaac tctttggagc
    21301 cagccaaatt ctcatgggcc gttatttcga accagagcag gtcttcagtc tttgcatcct
    21361 gattgccctc atctacttca gctttaacct agcaatttct agcctgtctc atatgctagc
    21421 caaacgttgg caacaagctg cagaataata ctcttcgaaa atctcttcaa accacgttag
    21481 ctctatctgc aacctcaaaa cagtgttttg agcaacttgc ggctagcttc ctagtttgct
    21541 ctttgatttt cattgagtat aaacagccac tctccagttc aattggagag ttttttgatg
    21601 agagtagata tttatagacc tcaatttgac accatacatt ttctatgata aaatgtaaca
    21661 aatttattta caacaaatcg aaatctaaat gaaatggaat tttctatgaa atcagtcaaa
    21721 ggactactct ttatcatagc tagttttatc ttgactcttt tgacttggat gaacacttct
    21781 ccccaattca tgattccagg actagcttta acaagcctat ctctgacttt tatcctagcc
    21841 actcgtctcc cactactaga aagctggttt cacagtttgg agaaggtcta caccgtccac
    21901 aaattcacag cctttctctc aatcatccta ctaatctttc ataactttag tatgggcggt
    21961 ttgtggggct ctcgcttagc tgctcaattt ggcaatcttg ccatctatat ctttgccagc
    22021 atcatccttg tcgcctattt aggcaaatac atccaatacg aagcttggcg atggattcac
    22081 cgcctggttt acctagccta tattttagga ctctttcaca tctacatgat aatgggcaat
    22141 cgtctcctta catttaatct tctaagtttt cttgttagta gctatgccct tttaggctta
    22201 ctagctggtt tttatatcat ttttctatat caaaagattt ccttccccta tctagggaaa
    22261 attacccatc tcaaacgctt aaatcacgat actagagaaa ttcaaatcca tcttagcaga
    22321 cctttcaact atcaatcagg acaatttgcc tttctaaaga ttttccaaga aggctttgaa
    22381 agtgctccgc atcccttttc tatctcagga ggtcatggtc aaactcttta ctttactgtt
    22441 aaaaattcag gcgaccatac caagaatatc tatgataatc ttcaagccgg cagcaaagta
    22501 accctagaca gagcttacgg acacatgatc atagaagaag gacgagaaaa tcaggtttgg
    22561 attgctggag gtattgggat cacccccttc atctcttaca tccgtgaaca tcctatttta
    22621 gataaacagg ttcacttcta ctatagcttc cgtggagatg aaaatgcagt ctacctagat
    22681 ttactccgta actatgctca gaaaaatcct aattttgaac tccatctaat cgacagtaca
    22741 aaagacggct atcttaattt tgaacaaaaa gaagtgcccg aacatgcaac cgtctatatg
    22801 tgtggtccta tttctatgat gaaggcactt gccaaacaga ttaagaaaca aaatccaaaa
    22861 acagagctta tttacgaagg attcaagttc aaataagtaa tcatactctc ctgggatttc
    22921 ccaggagagt tttttatagc caaatgaaat aagacaggaa cgatggaatt ttggcattca
    22981 aatcaattga taagaatgtt ttatagtgga gtgaaatagg atacgaacaa attgattagg
    23041 aaaatcaaat gaatttatag aaatctttta gcagttatgt tgtcctattc tagtttcaaa
    23101 acgctataga agcagcattg tgctagtcta gattcagttt actatactaa aacgagtagc
    23161 ttgaaatcaa aaaacccacc ctcacaggca ggttttatct gtattattca gctagattat
    23221 gctttacctt ctgaaccgaa tacgtcgata cgttcttcaa ccgatgcttg gatagctttt
    23281 acaccgtcag ccaagaattt acgtgggtcg aagagttttt tcttgtcgta ttctgcttcg
    23341 tttgcttcgt agtcacgagc aaatttacga gttgcgttag cgaatgcgat ttggcattct
    23401 gtgttaacgt taactttggc aacaccaagt ttgatagctg cttggatttg ctcatcagga
    23461 atacctgatc caccgtgcaa tacgattggg aatcctggaa gagcttctgt caatttttgc
    23521 aagtggtcaa ggtctagacc ttcccagttt actgggtaag ggccgtggat gttaccgata
    23581 ccagctgcca agaagtcgat accagtttca accattgctt tagcgtcttc gattggagcc
    23641 aattcacctt taccgatgat tccgtcttct tcaccaccga tagtaccaac ttcagcttct
    23701 actgagatac ctttagcgtg tgctttttca acaacttctt tagccaattt aaggttttct
    23761 tcaactggaa ggtgtgaacc gtcaaacatg attgaagtat aaccaacttc gatacactca
    23821 agtgcatctt cgtagtgacc gtggtcaagg tggatagcta ctggtacagt gatacccatt
    23881 gattcaacaa ggttagcgat caagttgcga gcaactttgt aaccacccat gtatttagca
    23941 gcacccattg aagtttggat caaaactgga gcttttttag cttctgctgc gcgcaagata
    24001 gcttgagtcc actcaaggtt gtttgtgtta aatccaccaa ctgcataacc gttgtcacgg
    24061 gctgcttgga caaatttttc tgctgaaacg attgccattt tatcaggcct cctgtatatt
    24121 tttatgggtc atcccattta cattgttcat tttatcactt tttgccaaaa aaatctagtt
    24181 tttcccgcag tttcgattga ttttcttcta actccatcta tgtaaaccct ttctccctag
    24241 tcttggacga cttttggaaa atctataaag aaggttaaac gattctcctc catctcgaaa
    24301 cgataagcta atttttcatg ttctaataga ctcttaacca caaagagccc cataccagac
    24361 cccttgacct tgcgactagc attgtcagaa aaagactggg ctagtttttc ttgttcctct
    24421 gagctacagc tattttcgat aaaaagttct ccttctcttt ctccaattcg aactaagcca
    24481 cctggaacag agtgcttaat ggcattgctg atgagattag aaagaatcaa cttcataact
    24541 gatgggttta gataagcctg ctgatgggtc aaactattgt ctatctggag ctctctttcc
    24601 tttgctagca aggcataatc tttgaccaga ttttgcgtca tctggaggag gtcaattgtt
    24661 tccctatcat ctcgcaattc ctgcacagaa gagagggaaa gtatctgcag aacatggtga
    24721 ttgagttcat ccacaatccc caaggcaact cccagatact ggtctctatc cttataacga
    24781 ccgatattct ctctcatatt ttcgattagg attttcaaac tagccagcgg tgttttcaat
    24841 tcatgagaag ctcctcgtag gaattcgacc ttcatcttct ccagctggag aatggcttca
    24901 ttcttttcat gcaagtccgc aataacagtc aagagatgct ggtagaggct attgatttgt
    24961 tccttgagat tacctatctc atccttagaa tccacgcgca atcgcacttg ggaatccagg
    25021 tccatcatcc gacgggtcac ccgcttgatt tccaaaatcg gtgcaacaat agtccgagcg
    25081 tagatgtagg ccaccaagag ggaaatcaga aaggaggcca gcaaggtata gggaagaaac
    25141 tggagactga tttgctccgc ttccttttgt aaatccatgg aagctagaaa ctggagaatc
    25201 atagtaccac cgtcttgcgt tttcacctcg cgctcctcaa taaagagaga ggttgtctgg
    25261 cggtctgtgt ccagaggaag actgtccttg acttctaact tgtcctcggt catctcacct
    25321 ttgacggtcc ccttgatatc actagtctgg gaatacaagt ctaacacttg ctcgatactc
    25381 tgcctatctt tcccttctag ggactgggca atggctgttg ccttttgacc aatggtttcc
    25441 tgacgatgac tcagataagt cgaaggaaaa agaaaataaa tagctaaatg aaggcagata
    25501 accagaacac taaatatcga gaaggtatag ataaatatct ttgcaaataa acctgttcgt
    25561 ttcattttcg ctccaattta taaccaacat tgcgcacagt gaggatacaa tccaagtcta
    25621 gctttttccg caattccttg atataaacat caataacacg gtcaaaggga acctcatctg
    25681 tcgctttcca gacggcatcg ataatctgag atcgagtcaa ggcccggcct tcatttttca
    25741 ctagatagtc cagaatttcc aactctttgg cattgatagg cacttcttgg cctgcgaggc
    25801 ttgcactgta gctttcaaag tccaccttgg tatccttgta agaaaagatt cgtcctgtat
    25861 cgtagtagcg cttgaaaatc gcgtccaccc tcacttttaa aagggagagg gagaaaggtt
    25921 tttccagata gccatctgcc aaagaggcaa aggcactcat cttgtattcc tcatcttgaa
    25981 aagctgtcaa catcaagaca ggaacctgac tggttttacg aatctcagct aggacttcta
    26041 agccgttgag cttgggcatc tggatatcca gtaaaaccag ggccacctca tagctagaaa
    26101 attgctccag agcttcctga ccgtccgctg cctcaatagt ttcatagcca caatccgtca
    26161 aataatcact gaccccctca cggatcatct cttcatcttc tacaattaaa attttcatac
    26221 tttaactgct ctctattttt tatttttctt agaataaata cctaccctat tttctattat
    26281 agtctcttgc tggccttttg tctgcaagca actgaccact agataaaacg ttgtgaaatt
    26341 cctttctcat aaattccata actttagtat attatattta agcactaaag tacaaagaaa
    26401 gcaactgaaa gcaatgattt tcaccactgc tttcggattt attttgaatt gttaaatagc
    26461 cattcctatc cactattctt gaatagaaac acaagatgca atctttattc tagactcatt
    26521 ttttcaaatt tattcaccat ccagcaagag ctcttttggt tgttttctaa ggagattgct
    26581 tgaagcaagc gccataacga gaaccactag aaccaaggca aggacaaaaa tgatgataaa
    26641 gtctgatgtc tgaatggaaa tgtctaggct cgacaaggtc ttgctaaagc catctacttc
    26701 tgcaccacca ccaaggttag aggcttgagc cgccttacta gcctgtttgg caacacctga
    26761 agtcacattg gcaaggacag tgtttccaat tgcacgggca gtgtaattag ctaggaagta
    26821 agcagaaact agagcaggga tagcaatcaa gatagattcg gtgatgaatt gacccaagat
    26881 acttgcctgc ttgaggccga tagagaggag aattcccact tccttgcgac gggcgttgat
    26941 ccaaaggctg agcaagaggg caaggaggag aactgagaag ctcaagctac cccagaagag
    27001 gaggttggcc atcttgtaca taccagagat agattgctca agagctgggt agttagagga
    27061 gctcttgacg agtgtgtagc tcttccagtt gataccactg atgccattca actctttcat
    27121 aacatcatcc aagttcttgt ctgctgttac aaagaaggtt gcgtccccat aaatggctgt
    27181 gtcttctgtg tatccataaa gttttgcagc agtgtgaatg tctgtaatag ctgtgttttc
    27241 gtaaagttct tgtgagtagg ttactgctga cttattatga ccatcaaaga gtcccttgat
    27301 tgtcacttca actgtttcct tggctccttt ttcattatct gcatcgtaga tattagagtc
    27361 cagtttaacc ttgtccccta ctttccagcc gtgtttggct gccaagtcct tgtgcaagag
    27421 gattttatcc ttgtcgtcgt tggttaagtg ctctccttcg actagtttat aagaaccaga
    27481 gacaaacttg tcttctttag aggagtcatt gacacctgta atcatcaagc tacttccaaa
    27541 acgcttggca cgatcagcag tgagattctt cttggtttct ggcgtttcaa tcaggtcata
    27601 tccagtcaaa tctccgatag cgttgatacg tttgacataa gactcaatgg ccttgttttc
    27661 ggtgattttt ttgatgtctt cacccttgat attcccagca ccacgaggcg ttccttggtt
    27721 gacgcgacga ttgatttgca tggagaagct attggtgata tttttaaagg tctcctgaga
    27781 agccttggca gtagctccct tgattgacaa gccgaccaaa ctcaagctcg ccatgaggag
    27841 aataatcagg aagatgacaa tcgatttgaa aaacttcctt gtaacatagg caaatgcgtt
    27901 gtgtaacata gattcccttt ctagattttg ttttaatcat tctattaaaa taagctcaaa
    27961 ttatttacta gtattgcgcg tttcagtcag tttcttatcc tttaattcaa gtgtaatatc
    28021 tgacgcttgt gccacttctt tactgtgagt tacgacaatc acacatttac ctgttttctg
    28081 ggcaagtgat ttgagtagtt cgacaatatc tccagcagtt ttaggatcca gatttcctgt
    28141 tggctcatca gctagaataa ctggagcttc tgagaccaaa ctgcgagcaa tggcaacacg
    28201 ttgctgttga ccacctgata actggagaac attccgcttg atctggcttt catccaaacc
    28261 aagctcaaga agtgtattct tgcttgcctt tttgttgacc aatcggatat tttccagcgg
    28321 agaaagataa tctatcaagt tataattttg aaagaccagg gaaatatggt gcatgcgatg
    28381 gtaagaatag cccttcttac gaatatcctc tccttgaaaa aggatagaac cttcaacagg
    28441 actatctaga ccagcaagta gggacaagag tgtggatttt cctgctcctg actccccaat
    28501 aatactgtaa aattttccgg gttcaaaatt ataattgatc tgatatagga ctgcttcagc
    28561 agtattctta taacggtagg taacatcttg taattgtaat aaagtcatga tttctccttc
    28621 ttaactaata gatgataaaa tttctttcgg tgattttcta aataagaata ggaaacaaag
    28681 ggctacagat aagcaactaa gcagaactag aaaaacatag gattctgcaa aagataagat
    28741 gctagttgat aaactgcttg ctttggctag tgtatcttgt aagcttgcct gatctccact
    28801 tgctagtaga gtttggagta ggtaagttgt gattgcgttt cctgcaacaa atgctggaag
    28861 caaagctcca agagatacca aaactacctc taaacagaat tgtaggaaga tcgagctctt
    28921 gccttttcca agtgcaagta aaatccccac ttcatagacc cgttctctca accagagaga
    28981 caaaaccaga attaaggctc cagctcctgc tatcaacatc ccataaagga agatggtcag
    29041 gaaggtttgg aaagttgcaa ctgagtcttt gatttgttca aaagccttgt tttccttttc
    29101 gacttggtag ccttgatttt ccaaagccaa gttttctacc tgcttcatga gtccgtccat
    29161 ttccttagga ttttctacat agaagcgtgc tgcactgact tgagcttcac tattgcccaa
    29221 aagggtttgg ctactttcat agtctgtaaa gacttgattt tcactgaagt cagaagacaa
    29281 gcctgtgaat ttctcttgtt ttttaccaga aaagatgccg ataatctcaa actctactgt
    29341 ttgtcctttt ccagattcag actgaccagc atccaagcca atcttgtcat gaagcgaaag
    29401 accgttcttc ttagccaatt cttcgtggat aaggattttc ttggaatccc ctttttgaag
    29461 gtgtcgccct tcttttagat tgaaagccga actggtaaag gttacatcct tggatgaatc
    29521 ctcaagagcc gttaagctaa ccaagttatt gtctgcagct gataaatcat cacgctccac
    29581 gctctgctcg ccagtcactg cttccttgtc ttttagtttt gcgaccgtct caagttcagg
    29641 agagacattt tccagcccct taatcttgct tacagatgct aggtctgaca acttgaatgt
    29701 ctgaccattc tctatcttct taatagaaaa agatgtattg agtgatttat aaagattgct
    29761 ttctactgtt ttgttggact tcatcagagt caaacaggct gaaattccgg ccaataagac
    29821 caataaaatc agaaataaaa taaaacttct cagtcgcttt ctgctgacat aagcccaaga
    29881 tctttggatt ggattcattt gtcacctcca tatttgtaag actattataa aacccaaata
    29941 tgaaatgttt atgaaatacg aaaaaaaaat atcgagtagg ggataatctc tagcccctct
    30001 cacaccacca tacgtgccgt tcggcatacg gcggttcaac taacttttaa cgcatgtcgt
    30061 tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt caaggactgg ttttgatata
    30121 gcacgtttaa gtaccgactt ctgagctact atagtagatt gaaactagaa tagtacacct
    30181 ctacttctaa aatattgtta gaaatcgatt tgactgtcct gaacgattcg tcctattctt
    30241 atttcatttt actataattg atagtggtcg ccccagccag ataccttatc tgctatccat
    30301 ttaggaaccc ctaacttaag caatccccat aatcgtctcg atttcttctt ccattgcttc
    30361 cagataatca ctcgtaggcg agtacgcaag cgctcatcta tgctagtgac tatacttttc
    30421 atatttataa ttcattcctt tcgtttcact caaggcacaa cacagaatga aaaagtgttg
    30481 tgatctttat tttgttttat aataatagtg agaaagccta tcactactac aaatcacggg
    30541 gaggtgaata agtgagtggt acagccacta cctcgcatat tttgtcacat catttaacgg
    30601 tacataataa gttgtaccat ctgaataagt tgctacaata tcatttgcat gctctccttc
    30661 acctttagca aaggttggag ctcctgctgg atgattttta tttgcctctt tcaatttttc
    30721 aataatggca ttttttctgt atcttttata ttatcaggat ttttcactaa gattttgtct
    30781 ggatatgtcg gtttagcaga aacaattttt actgttattt cttttttatt cgaagcactt
    30841 gtccagtttc cagcattatc tttagcattt aattttacag taattcctga actaggaact
    30901 tcagtagcag gttgattatc aacattattc aactttaatt tcaaaagagc tgttgcatca
    30961 gacgttttat caatcgttat atataatgat gaattgttat tataaccagt ttcttcatat
    31021 ttagctgttt gtgagctact tgaaacagaa ctgaaattat gcccactacc tccctgatta
    31081 tcttcaatgc ttacgtctaa atgaacttcc ccactattat ttggcttagc aacaactgtt
    31141 atagtaaaat aacataaaat ttgcataaat agattaggta aatcaaagca acttctagga
    31201 atgttttagc agtcacagtg tactttccca gcatcaagcc actataactc tgcacataaa
    31261 aatggagaag atggcaatcc tcttctccaa atattaactt ctttacaaac caactatagt
    31321 tgacaaagaa cctaaaatca attgataaca caaggtcagg tcggtcaact ctttcaactg
    31381 aagccctgtc aactcttccc atttatcaat cttgtattgg agagaattgc ggtgcagata
    31441 gagttgctgg gctgttttag tgagaacagc actattttcc caaagagaga gaatgatttc
    31501 ctgaatctga tcttgatcca aaatcatctg gtgtagacat tctttaattg gcttcaagtc
    31561 cacgagtctt tctcccatac tccaaagata gagctgagaa aaagtatgaa caccttggtg
    31621 accctgacgc caccatgtct tgaacaaatc ccgctcagct ttgattaagt ctgatagggc
    31681 ttgatgtcct gtctgagacc aaacctgacc caacatgata gaaagacgaa gtccaaagtc
    31741 atactcaacc gcttcaatcg tatcacttaa aatatctctt acagaagtgt atttgtcttg
    31801 ttgaagcacg aaaacataat cctgagctcc gacctgtagc actgtctgac aattcggaaa
    31861 aagagtccgc atcatatcta gccaagaagc cagattttcc tgctgaaaat aagaaagatg
    31921 gcaataaacc aactgaatct ttttaaaaac ttgcggtgcc tgtcccttgc cttcaaccag
    31981 ataggaatac caagggttta gcgaacgagc ctgctcctgc tgggtcaaaa gggcaaccaa
    32041 ctgcttttca cgctcgctga gcccagcttc ctccagcaaa atccactgct gagaagctaa
    32101 agggagcgtg agatagccct ctttctctac tggttggtct gaaatccgag cctcaggaaa
    32161 ccagtcttgt agttcttttg ccctcatgtt ctagccctcc actttttgga tgcaccatga
    32221 aaccaaactc tcaagacgtt ccagattctc agtcatatgg agatagccca taaccgcttc
    32281 aaatcccgtg gacatacgat aagtcacgac atctgcattt ttagcctttg tgtggctatt
    32341 ggtattgcgg ccacgtttat agatttcttc ttctttttcc gttaggacct gctcctccaa
    32401 catgagagca atcaggcgag cctgagcctt ggctgacaca tacttggttg cttcttgatg
    32461 gagtttattg ggtttggtca tacctttgag gatgaggtga cggcgaatat acatagaata
    32521 caccgcatcc ccctcaaagg ctagcgcaat cccgttaatg agattgacat caatcacgtg
    32581 tccacctcac tccatctttt gtatccaata gtttaatgcc ttgagcagcc agttggtctc
    32641 ggatttggtc tgctgtctca aagtctcgat tggcacgcgc ctcttggcgt ttttgaatca
    32701 agtcttcaat ctctgcatcc aaaacttcct caacaaagac aattccaaaa atttctaaca
    32761 tatctgcaag agcttgcttg acacttgcat catagttccc tgagttgatc catttggcca
    32821 tttcaaagac aactgtgata ccgttggcag cattaaaatc ttcatccata gctgctacaa
    32881 acttatcttt aaagttttgt aactcttggg catccacgtt tcctgtaaat ggttgttcgt
    32941 aagtattctt cagatacttg agattggtct cggcatcgcg aactgccttt tccgtgaagt
    33001 tgataggctt acggtagtgc tgggtcgcaa agaagaaacg aagtacttgc ccatcaagag
    33061 ttttaagggc atcgtgtacc gtaatgaagt tacccaagga cttagacatt ttgacattgt
    33121 cgatattgac aaagccattg tgcatccagt agttagcaaa agccttgcct gttttagctt
    33181 cagattgggc aatttcattg gtgtggtgtg gaaactctag gtcagctcca ccaccgtgga
    33241 tatcaatggt atcacctaaa atctctgtcg acatgactga acactcaata tgccaacccg
    33301 gacgtccagg tccccaagga ctatcccaag aaatctcacc tggtttggaa gatttccata
    33361 gagcaaaatc tacaggattt tccttacgag ccgtttcttc atcggtacga cctgaagcac
    33421 ctagatccaa atcttccaag gttttattag ccaatttagc atagttgtgg gatttttcta
    33481 cacggaaata gacatcccct tgactctcat aggcaaagcc tttctcgatc aagtcttcca
    33541 caaaacggat gatgtctgcc ataaactcca ctacacgcgg atggcgagtc gcaggtttca
    33601 cgcctaaggc cgtcacatcc tcacgaaagg cagcgatgta cttatccgca acctcctgag
    33661 gcgtgatgcc ttcttccctg gcacggttga taatcttatc atccacatct gtaaaattgg
    33721 aaatataggc aaccttatac ccacggtact caaaatagcg acgaatcgta tcaaaagcta
    33781 ctgtcgaacg ggcgtttccc acgtggatat agttgtacac cgttggccca caaacataca
    33841 tcttgatctt gccgtcctca atcgggacaa attctcgcaa atcacgagac atggtgtcat
    33901 agattttaat cataaatcat aatcaggaaa gctgaaatcc aagaacaatt agtttcatca
    33961 ctaaaagttc aagtaaattt cagtccgaat atctctacac ttcggaatcc cttgctcctt
    34021 tctcattcag ataaaccacc tgagtctgtt tgacaaagcc aattttttca tacaaacgtt
    34081 tggcacctac attgctatct tccactgcaa tctgaaattc cttgtcattt tgctcaatta
    34141 gttggttgac gagggatttt gctaagtagc ttccatagcc ttttccacgt tcaggttcca
    34201 atattgctaa accgtagagg taattcgtat tagtcgataa atcaaccgta caagttccaa
    34261 taacctgacc agcttttaat aaaatatata gtcggctttc tggatctttc agagcttcag
    34321 cgacatatct atccacaact tctctcgatt catgttcctc tgaaaatgcc tgaaatttta
    34381 attgactaat ttgatcctga tacgaactat ctgctaacaa aatttcaaga tgggaaacat
    34441 ttgctaacgg ataaggtctt ctatccttac ctaaccaagt ttctgtctct tcatcctcga
    34501 ttagtcccca gttactggca aagtcaggat gattctctaa aaaaatacgt tctgtctgaa
    34561 aagtgactga ccgaatgggg aaagaagctg tttctctctc aaaactagta aacaatgcac
    34621 gcgcaatccc ctgacggcga tgacctggat gaaccagtat cgtcacttct acatcttggt
    34681 catctgcata gacagttaat aaaccaacaa gttcgccttt ttcataataa aggaaaaagg
    34741 cgggcatgtt tgggtcaaaa ttaagcatgt tagagagata gggatcgcga taggtaccgt
    34801 catagttttg gcaacagtta attacttttt tcgcctcaga tagctcctct tggcttaact
    34861 tgtttcttgc ttgaatcata taggtatcct ctacaaacca gacgatctgt gactggcatc
    34921 tttagcctgc tcgagtttat tgacataata ctctcgtttt tcttcgactt cgtgaatgac
    34981 aggctcatct ttcttaccat gaagacggac aatcttggcc ggaataccga caaccgtcac
    35041 gtcactaggt acatctgcta cgacaactgc tgcagcaccg accttggcat tttcaccaat
    35101 ttccacaggc ccgataactt gggcatgggc tgatatgagg gctccctttc gtacagtcgg
    35161 atggcgtttg ccacagtctt tccctgttcc cccgagagtc actccgtgat agagaagaac
    35221 gcctttttca acaatcgctg tctctccaat caccagacca gaaccatggt caataaaaac
    35281 acctgaatca atctgggctc ctggatgaat ctcaatctga gtccaaaagc gccaaaactg
    35341 actgtacata cgagctaata gtttgaagcc gtgcttccag agaaaatgcg agagacggtg
    35401 ggccgccaag gccttgacac ctggataagt cagcaaaacc tccaaagtgg tgcgggccgc
    35461 tggatcattt tcttttacaa tatcaatggt ttcgcgccac caccccatac atttctcctt
    35521 ttcttattct gaatcttttg gtgtttctgt aaattctttc ttaggtttgt aatccttgtg
    35581 atgacgtggg cggtgagggc gctcagactt ttcacctttt tcatcatgct caggttttgg
    35641 cggacgaggt agaagagcct tcatagaggc atcgatacgg cctttttcat caatcttgat
    35701 aaccttaaca tcaacttcat ccccgatttc taccaaatcc tctacacgat tggtacgagt
    35761 ccaagccatc tcagagatat gaacaagggc atctgtctta tcaaagaggt taacaaaggc
    35821 accaaatttc tcgatacgaa cgactttagc acggtaaact tcatccactt tggcttcacg
    35881 aaccaaacca gcaataattt ctttggcacg gttaatagca tcttggtcac tagagtagat
    35941 agacacattt ccttcttcgt ctatatcaat cttaacacct gtttcagcga taatcttgtc
    36001 gatggtttct ccacccttac cgatgacaat cttaatcttg tccacatcaa tcttgatcgt
    36061 atcaattttc ggagcagttg gagccaattc tagacgaact tctggaatgg ttgcttcaat
    36121 gacatcaagg atttcaaaac gcgctttctt ggcttgagca agagcctccg tcaagatttc
    36181 tgcagtaatc ccttgaatct tgatatccat ttgaagggct gtaatcccat cacgagtacc
    36241 tgcaaccttg aagtccatat ctccaaagtg atcttccaaa ccttggatat ctgtcaatac
    36301 tgtgtagtta tttccatctg agataagtcc catagcaata ccagctactg gcgccttgat
    36361 tggcacacca ccagccataa gggcaagagt tcccgcacag atagaagctt gagatgaaga
    36421 accgtttgat tccaaaactt ctgctactag acggatagcg tatgggaatt cttccaagct
    36481 tggcaagact tgagcaagag cacgctcacc aagggcaccg tgaccgattt cacgacgacc
    36541 tggcgcaccg taacgacctg tttcccctac agaatattga gggaagttat agtggtgcat
    36601 aaagcgtttc ttgtactctg gatccaaacc atcaatgatt tgagtttctc ccatcggagc
    36661 caaggtcaag actgaaagag cttgagtttg cccacgagta aagagacctg aaccatgtac
    36721 acgaggaagg aagtcaacaa ccgcatccaa aggacggatt tcatcgacct tacgaccatc
    36781 aggacgcacc ttgtcttctg taattaaacg tcgcacttct gcgtgttcca tttgttccaa
    36841 gatttcagcc acatcacgca taatacggtc aaattcttcg tggttcgcat atttttcttc
    36901 gtaaacggca gtcacttggt ctttcactgc ttgagttgca gcttcacggg ccaatttctc
    36961 ttctacttga actgcctttt ggaggtcact gttgtaggct gcaatgattt cagcttgcaa
    37021 ttcagcatcc acgtgaagca attccacttc tgctttttct ttaccgacag cagcaacgat
    37081 ttcttcttgg aaggcaatca attctttgac agcttcgtgc cctttaagaa gcgcttccaa
    37141 catgatttct tctgacaatt ctttggcacc agactctacc atgttgatag cgtgcttggt
    37201 tccagctact gtcaattcaa gaagagattg ctctgcttgt tcttgacttg ggttgatgat
    37261 gatttggcca tctacatatc ccacttgtac cccagcaatt ggtccgtcaa atggaatatc
    37321 tgaaatagac agtgccaaag atgaaccaaa catagcagcc attggtgcag atgcattttc
    37381 atcataagaa agcactgtat tgatgacttg gacttcatta cggaaacctt ccgcaaacat
    37441 aggacgaatc ggacggtcaa tcaaacgcgc tgtcaaggtc gcatctgttg aaggacgtcc
    37501 ttcacgtttc ataaagccac caggaaactt cccagccgca tacatttttt cttcgtagtt
    37561 gacttggagt gggaaaaaat ccccagttgc cattttctta gacataacgg cagcagtcaa
    37621 gacagttgac tcaccgtaac gtacgacaac agagccattt gcttgcttag caacctgacc
    37681 agtctctaca attaactcac gacccgcaaa agtcgtttga aacacttgtt ttgccatttt
    37741 aatccccttt ggattgatga aattatacgc cttgcctaca aagatcaaga taccaaggac
    37801 gtcaaaagca aagtaaaaat aggaaactga cgaagtcttc gatgaagaca agacagttta
    37861 tcttttttac acagcttttc ggccgtgttc aattactcaa gatgctaagc cgtcaagcaa
    37921 ctcaaaggaa aataggaaat cgaacgacgg agcgactgct cctaggcaga tttatctttt
    37981 tccacagagt tgtaggcgtg ttcagttttc aagatacatc attagaaagg tttaatatta
    38041 aagtatctaa acctttcacg ctaatcgcta tcgggcgatt agctaaatgc tttactaact
    38101 ctttcgtcaa ataacatcga tttgactcac tcgtgtcgtt aaatcttaca gtttaaatgc
    38161 attgtattat ttaatacctt catctttgta tcaagtacgt acagaatcta ttttatcata
    38221 tttttcttaa aaagtgaggt ctttaccatt aaaaaggaac cattcccctc acctgagaag
    38281 aatggtttgc ttttattatc ctagagactg gtgattaaac aaggcatggg ttgcttgatg
    38341 gatgtatttt gctgtatcag cattattcat cgtatagaga tgcacaccgg caacatcctg
    38401 agttaccaag tccacgattt ggtccactgc ataggcaagt cctgctgctc tgagcgactc
    38461 agggtcatgc tcatacttgt ctaagatggc tttaaatttg cgtggaagat ggatattctc
    38521 acaagtcttc aagagtcgga gagcctgatt tcgattcaga attggcataa ttcctgcatg
    38581 aatgggaaca tcaatcccag ccaagataca cttgtcctga aaatcataga agcgctcatt
    38641 gtcaaagaag agctgagtta cgaggctcga acagcctgca tccactttct tcttaagatt
    38701 ttgaatatct gaaatctgat ttggcgaatc tggatgccct tctggatagc aagctccaat
    38761 aatatcaaag tgaggggttt gttccttgat aaactcaatc aagtcggttg catagcggaa
    38821 atccttttgt ggttccacgt ctggaataat atccccacga agagccaaga ttttctgcac
    38881 cccaactttg tccaagtcag caatagtttc agcaaccttg tccttagtta gataaatagc
    38941 tggcaagtgg gcaatggtcg gaatcgccaa atcattttgg ataaagtcag ccaaacgaac
    39001 cgtcgtttcc ttgatattaa atttattatt gctggcagtt acactgataa aatggggagc
    39061 caactcctgc atatcctgca aggctgaaat aatgttatca ttacccacgg ctgggtttgg
    39121 agggaacact tcaaatgaga gtgacggtgt ttggcgtgac atatgtaata accttttcta
    39181 gttgatttct ttttgaacaa ccactgtatg gagagaaatc caatcttaca atttctcacg
    39241 cgcagcttta gctgcttcaa caaggcggat caagctttct tttgtttctg ggataccacg
    39301 tgttttcaaa ccacagtcag ggttgatcca aactttcttg cttggcactt tagcaaggat
    39361 ggcttcgatt gtgttgtcga tttcgccttc atttggtaca cgaggtgagt ggatatcgta
    39421 aaccccaggt cccacttctg tttggaagtt tttcgctttg agttcgtcca agatttcaag
    39481 gtttgaacgg ttagcttcaa aggaaataac gtctgcatcc atgttatcga tagctgggat
    39541 gatatctgta aattctgagt aacacatgtg agtgtggatt tgtgtgtctg gcgctactgt
    39601 tgagtgtacc aagcggaagg caggaatagc ccagtcaagg tagtcttcgt accagtcgct
    39661 acggcggagt ggcaattttt cacgaagagc agcctcgtcg atttggatga ttttcacacc
    39721 agcagcttca aggtcaagta cttcatcctt gatagcaagg gcgatttgga gagttgaatc
    39781 cttgatagag atgtcttcac gtgggaatga ccagttaagg atggtaacag gtccagtcaa
    39841 cataccttta acaggtttgt ttgtacgact ttgtgcatag ctagaccatt taacagtgat
    39901 agggttaaga cgagtgacat caccccagat gattggtggt tttaccccac gcataccgta
    39961 tgattgtacc catccatttt tagagaagag gtatcctgac aagttttgac cgaagtactc
    40021 aaccatgtca ttacgctcaa attcaccgtg aacaaggaca tcaaagtcaa tatcttcttg
    40081 ccacttgatc cattcgtcaa tcgtttcagc aaggaaagcg tcgtactctt tttgagacaa
    40141 ttcaccttta cggtaagcca aacgtttggc acgaacttct tttgtttgag ggaatgaacc
    40201 aatcgttgtt gttggaagag ctggaagttt gaaagcttct tcttggatag cttcacgttc
    40261 tgcaaaggct ggcaaacgag tgtagtctgc gtctgtcaag ccagcgatac gcgcacgaag
    40321 ttcagcattt tcaccaacac gctcagtcgc aaagagttct ttgttggctg caagagcttc
    40381 tgaaccttga ccatttcgga tagcatccaa gtcacggatt tcatccaatt tttcaactgc
    40441 aaaggcaaag tggttcaaga gtgctggttc aaattcttca ttagcagttg taaatggcac
    40501 atgaagaagt gagcaagagc ttgtcaaaac gatgttttca gctggaattt gctcaagaac
    40561 agccaagctc ttttcgtagt tgttgcgcca gatgttttta ccattgacaa tacctacata
    40621 gagagtcttg tcagctggga agccaccttt aacgagttca agagttttct taccttcaac
    40681 aaagtcaaga ccgatagcat ctactggtaa gtttacaagg tcagcgtata cgtcacgaac
    40741 atcaccgaaa taagtttgaa gcaagacttc aagacctttt ttgtcagcca agagtttgtt
    40801 gtaaaggttc aagaagagag ctttttcttc agctgtcaag tcttttacaa gagccgcttc
    40861 atccaattgg atgcgagtcg caccaagttc agccaattta gcaaaaactt cttggtaagc
    40921 agccactaag ctatctacga agtcgtctgc tttcacgcct tcttcaaagt ctgacaattg
    40981 aaggaaagtg aagggaccta caagaacagg acgagtgttc aatccaagtt ctttggcttc
    41041 ttggaactca tcgaaaatct tgtgaccagc caattttact tgagtgtctt tttcaaattt
    41101 aggaacgatg tagtggtagt tagtgttgaa ccatttcttc attggaaggg cgcgaacgtc
    41161 ccctttttct ccctggtaac cacgtcccaa agcgaagtag cgctcaaggt cagacaagtc
    41221 caagttttga acggatgcag gcaccacgtt gaaaaggaaa gccgcatcta ggaagttatc
    41281 atagtgagaa aagtcatttg atggaatttc agtgatgcct ttttctttga caatgttcca
    41341 gtgtttagca cgcaagtctt ttgctgctgc taaaagttct tcttctgaga tttcttttct
    41401 aaagtatttt tcagttgtaa attttaattc acggaattcg cccaaacgag ggaaaccgat
    41461 gattgtagtt gacatgatgt gtcctccaaa atttgttgtt gaaactatct taacagaaaa
    41521 gaaagcgtct gtataattgt aaaaaattag ggtttgatat agtttgaaac tatatatctg
    41581 tttcggacaa aagaaaaaga cttgaagcaa acgtctcaaa tcctttgtaa ttcttacttt
    41641 acagctatat tccaattaga atactaaaac atgttattag taattcttat aagtgactat
    41701 gacctgttat tagaaaagac tataactgat tctagtcaac tttttccctg ttcaagtggg
    41761 acgattgcta gtgtctttcc taaactggct aggactttta agactgtatc caactgagga
    41821 ctagtctttc ctgtctccat cctagctatg acaggctggc ttattccact gacttcttcc
    41881 agctttttct gactgattcc ttgttcatac ctagcctcaa tcaactcgct catgatagcc
    41941 actcgcatat cactttcaag gatttcctcc ttgctaaaga gctcagatgg acatccttcc
    42001 aattactccc aatagcacta ttcttcatca cttaaccctc ttttttttac gtctatgtat
    42061 ttttaaaaaa atgagcgaat tatgattcga tagattgacc agtgggttta aagttggtgc
    42121 tagcctattt cttaagcgat tttccttttc taggataaag cagttcctgc ttgcttaacc
    42181 ccaattttcc acgatgaatc caatagtaaa tggttgaaat tcccacgtta acccctttag
    42241 ccatcaccat catttcaggc gaaaattttt ggttatgttt ttggttatgt atagtggaga
    42301 atcttttcct ttagtttctt aagactgttg agcgtagtcg gcagaataaa tctctttgaa
    42361 gcgccctttt ccaagacatt gtcggactgt cccacgcttg atttcagtgt ggatagtttg
    42421 aggagctttt ccaagtagag aggcaatttc tctatttgat tttccttctt ttttccatcg
    42481 ttcgattaag cgacggctat cgattgtcaa atgtttgcct tttgtagtat aattgtcttg
    42541 catttctgtg ccttttaatc atttcaatct taaattggac tttttttact tgggttgtac
    42601 ttaatctatg aggaagacaa gaaaaagaat atcaatcaag taaagtcaca aagtcacatt
    42661 agctccgagc aaccattgca aattgaggta ctcacacaat gattaaaaca tttctctctg
    42721 ccctttcggt cattctcttt tctatcccta tcataactta ttcttttttc ccatcttcta
    42781 atcttaacat ttggctatct acccaaccta tcttggcaca gatttatgcc ttccccttag
    42841 ctactgcaac tatggctgct attttaagtt tcttattttt tttcctatct ttttacaaga
    42901 aaaataaaca aatacggttt tactctggca ttttgctctt actatcgctc atattactat
    42961 tattcggaac agataaaacc ctttcttctg catcaaataa gactaaaacc ttaaaattag
    43021 taacttggaa cgtcgctaat caaatagaag cacaacatat tgagcgaatt tttagccatt
    43081 ttgacgccga tatggctata ttccctgaac tagctaccaa tatcagaggt gagcaagaaa
    43141 accagagaat caaactattg tttcatcaag ttggactttc tatggccaac tatgatattt
    43201 tcacttctcc acctaccaat agtggaatag ctcctgtgac tgtgattgtc aagaaaagtt
    43261 atggtttcta tacagaagct aaaacttttc atacaacacg gttcgggaca attgtattac
    43321 attcgagaaa acaaaatata ccagatatca ttgccttgca tactgctcct cctctgccag
    43381 gtttaatgga aatctggaag caagacttaa acatcattca taatcaattg gcttcaaaat
    43441 atccaaaggc tattattgca ggtgatttta atgcaactat gcgtcatgga gcacttgcaa
    43501 aaataagctc tcatagggac gcattaaatg cactgccacc ttttgaaaga ggaacttgga
    43561 atagccaaag tccaaaactt tttaatgcaa caatagatca tattttattg cctaaaaacc
    43621 actactatgt taaagattta gacattgtaa gttttcaaaa ctctgatcat agatgtattt
    43681 ttacagaaat cacattttaa ttattttata taaaatcacc cctctaatgt tcataaacta
    43741 gagggggaat ttgtatccta ctatcgttta acgcacttct gcattcactt tttcttcgag
    43801 agacgcttgg attttttcca tatagcgtgc gacttcttcg tccgttaagc tgtcttctgg
    43861 attttggaag gtcaagctat aagccattga cttcatacca agtcccagtt tttcacctga
    43921 gaagacgtca aagagtttga tatctgtcaa acgtttcacg ccggcagctt ggatagcatc
    43981 tacaacttct tggtgagtca cttctgcctt gaggagaagg gcaacgtcac ggctgactgc
    44041 tgggaatttg gtgatttcca caaatggaac agcaggttgg agcgcccctt cgatggctga
    44101 aaggttaagc tcagctacat acgtttctgg aatatcgtaa gccttggcag tgactggatg
    44161 cacttggcca aggaaaccaa gaacttggtc accgagtgaa atcacggctg tacgacctgg
    44221 atgaaggcta acgatttcag atgttgctgt ataggttact tggagtccca aacgagtaaa
    44281 tagggcttca aggattccct tagcatagaa gaaatcaact ggaactgctg ctgtttggaa
    44341 atctttttca gcaaccaagc ctgtcaaggc aaaggcaaag ctgttgatct catttggaag
    44401 ttcttctttt ggattacctg tttgttcaaa gacttttcca atctcataaa gggccaagtt
    44461 tttattctta cgagccacgt tgtaggcaac ggtatcaagg atccctgaaa tcatattttg
    44521 acggaggact gaacgatcca cagtcattgg ccacatgagt tcagtaaggt tacttggttg
    44581 agctgtgaac tcaactgctt tttcaggagt tgtcagagca taggtgatga tttctgtcaa
    44641 acctgctcct tcagcaatgg tacgaacttg acggcggagt ttttgtatca cagtcaattc
    44701 accagctgta ccatcgtctt ttggaaggct ggttggcaag cggtcatatc catagatacg
    44761 agcgatttct tcaaagagat cagcttcgat tgtgatatcc caacgacgac gtggtacgct
    44821 gactgtaaag ctgtctgcat ttccagaaag accaaagcca agacgacgga agacgtcttc
    44881 tacatcagca taagacagct cagttccgag gacacggtta acatcagcaa gggttgaaga
    44941 aacttccaca tcagaggtat caagctcacc cgctgaaacg atacccttac gcaccgtcgc
    45001 gcctgcaagc tctgcaatca tgctagctgc cgcatcaagg gcttcattaa ctgttgccac
    45061 attaattcct ttttcaaagc gagaagatga ctcagaacga aggttcaggc gaccacttgt
    45121 cttacggata gatttgccat taaaaacagc agcttcaagg ataacacgac tagatttttc
    45181 agaaatttct gtagcctgac cacccataac accggcaagg gctactggtt tgtcagcaac
    45241 tgtaatcacg aggtctgtct cagccaagtc tcgttcttca ccgtccaggg tcactaattt
    45301 ttcaccatca cgcgcttcac gcacacggat gtcagtccct tcaaatgtgt ccaagtcaaa
    45361 agcatgcata ggttgaccaa agtagagcag gatgtagttt gtcacgtcta caacgttatt
    45421 gatgggacgg atgccttcgt tcatgagaag gttttgcaac cattgtggac ttggtgcgat
    45481 agtcacattg tccaagatac gagctgcata gtaaggcgcc ttgtctgtct caatgctgac
    45541 agaaagggca tctgccgcag cttcattagt ttctgttaga gtaaattttt taaagttgac
    45601 tgccttgtca tagatggctg ccacttcgtg agccactcca cacatagaaa gggcatctgc
    45661 acggtttggt gtgatggaaa gttcgatgat ttcatcatcc aagtctaggt aagaaaagac
    45721 ttcctcacct ggcacggcat cttcaggcaa gatttggatg ccatctgcga attccttagg
    45781 cacaactgag tcagaaattc ccaattcacc aagtgaacag atcattccaa gtgactccaa
    45841 accacggatt tttccttttt tgattttgta gttatcagcg atacgagctc ctggaagagc
    45901 caccatgacc ttgatcccag cacgcacatt tggggcacca caaacgatct gacgctcttc
    45961 ttcttcgcca acgttaatct gacaaacatg gaggtgagtc tctggcacat cttcgcaaga
    46021 caagacctca ccgacgacaa tttttgagag accagcagct ggtgattcga caccctctac
    46081 ctcgatccct gtagttgaca ttttttcagc caactcttgt gatggcacat caatgtccac
    46141 caattctttt aaccatttat aagatacaag cataatttag ttctccagaa tgacagttgt
    46201 cactctagtt cttttccttt cctatcattt caatagaaga atcctcttct taccttaatt
    46261 tctttctcag taaccaatcc gtatctactt tttgaccaac cataaaatga tgttggctaa
    46321 atttttcaaa accatatcgg ttataaaacg cttgagcttt tgtattatgc tcccaaacac
    46381 ctagccaagc ccaagaaaaa ctattttttg tagcaagttc aagtgcgaat tcaaacagtt
    46441 gcttacctag tccaaatcct tggaattttt gtagcacata gaggcgttga atttcaaaag
    46501 cgtcctctaa ttctctctca gtttgagcac ttccccagtt gactttgaga aaaccagcta
    46561 tctcctcctc atgcataatg aaataggttt cagagtcagg atttcccaac tcagttgaca
    46621 aagttttcag actataagcc tcttcaaagt attcctgtaa ctgctcttcc gtattatcat
    46681 acgcaaaggt ttcacgaaag gtttgtttgg caattttagc caacacctca acatctgcca
    46741 tttctacttt tctaatcatt atttaaactg ttctgagaag cggacatctc cttggtagaa
    46801 tccacggata tcgttgattc cataacggag catagctaca cgctcttgtc caagaccaaa
    46861 ggcaaagcca gagtatacag tcgcatcgat accactcatt tcaaggacac gtgggtgaac
    46921 cataccggcc cccataattt cgatccaacc tgttttctta catacattac agccttctcc
    46981 accacacttg aagcaagaaa catccacctc aacagatggc tctgtgaatg ggaagtaaga
    47041 tggacgcaaa cgaatttgac gctcttcacc aaacattttt tggacaatca actgaagcgt
    47101 tccttgaaga tcagccatag agatattttt cccaactacc aagccttcga tttggtggaa
    47161 ttggtgactg tgggtcgcat cgtccgtatc gcgacggaag acacgccctg gcgagatcat
    47221 cttcaaagga cctttagaaa aatcatgggc atccatagca cgcgcctgaa ctggagacgt
    47281 gtgggtacgg agcaagattt cttcagtgat atagaaagta tcctgcatat cacgagctgg
    47341 gtggtctttt ggaaggttca tacgttcaaa gttatagtag tcttgctcca cttcaaaacc
    47401 atccacgact tgataaccca taccgatgaa gatatcttcg atttcttcac tggtttgtgt
    47461 caaaacgtga cggtgaccag tcgcaactgg acgacctgga agcgtcacat ctatactctc
    47521 gctagccagt tgagccgcga ctttcttttc ttccaagagc ttagctgttt cttcaaaagc
    47581 agcagtcaag acatcacgag cttcattgac gtgtttcccg atgattggac gcatctcagc
    47641 agaaacatct ttcatccctt tgaggatttc agtgagcgaa ccctttttac caaggacaga
    47701 gacacgcaaa tcttgcatct ctttttcatt tccagcagta atctgcttca agctagccag
    47761 cgtttcttcg cgaagcgctt ttaattgttc ttcaatagtt gacatatttc ctccatcagt
    47821 ctctcgtaga taaaaagaaa accacatgcc aaaaactcca ctcggagcgt tgacacgcgg
    47881 taccatccgt tttcatctga caagtcagac cttcatttct aaatccatgc gcaagtgaat
    47941 tcacccagct ttcatataga gagcttgcag tcacggctct cctccctgat atacttccct
    48001 tgggctacta gtctttcaga ttcctattca attactactt agtttatcag atttttacca
    48061 ttcttgcaag acctatctta cttctgcttg ttagcttatt cttatctaaa tttatataaa
    48121 caatttatct aaattaacta tttataattt ttgtaacaaa attaaattaa ttgacactcc
    48181 cctataaaat aaagaagttt agaatttaat gtcttccaaa cttctttatt ccatatttaa
    48241 tgaaatgcca ccttaaccgt gataatagct agtcatcaat aaaaaactat ttgaataagg
    48301 attctccatt tgattcaatc acttctttat accaagtaaa agacattttc ttatatcgat
    48361 ttaatgtacc acttccatca tcgtttcgat caacataaat gagaccgtac cttttagaaa
    48421 gttgtgcagt ggacatagaa acacagtcaa tacatcccca agacgtatag cccataattt
    48481 caacaccatc ctgtagagct tcagcaactt gcaataaatg ttctttcata tactgaattc
    48541 tataatcatc ttggacggtt aagttattaa gttcatcttt tattagttga tctttagcac
    48601 ctaatccatt ttctactata aataatggga tttgataacg gtcataatat ctatttaaaa
    48661 ttatacgtag tccaattgga tcaatttgcc atccccactc tgaagactct aaataaggat
    48721 ttactaaacc accaataata ttcccttctc ctgaattata ctgtgttgga agagcagatt
    48781 gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt tttaataact
    48841 ctgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat ctttttgcat
    48901 aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga ttctcatact
    48961 catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc atagctaata
    49021 ccatacatcc caccttaaac tctgaattaa tctcacgagc aatttttgta accaaacttg
    49081 aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga ttctccttag
    49141 gtatatctat tcctccacta gtaaatggta attccaaaac agagtttact tcgttaaatg
    49201 taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca aatttttcat
    49261 aaaaatgaat cattctccta tcaacccatc catgatattt tcttgctaaa tataatggag
    49321 tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt tcatcaaaca
    49381 attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct tttggaaaaa
    49441 ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa aacaaggata
    49501 tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta tcttctgtag
    49561 gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact gataagccct
    49621 taccatcttc attatatgct ccctctactt gattagctgc aacagctcca ccccaaagaa
    49681 aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt aattccttag
    49741 aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca ttggtattcg
    49801 ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc aagtccattt
    49861 caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta ataaaacctt
    49921 gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca ccctcatcac
    49981 tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca tcaaatggtg
    50041 cataaacctt accttcactt gggataatcg ctactccgtc tccaattagt ttatctgaaa
    50101 atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga gaaaatatca
    50161 tttttttatt tgaaactcca gcttcaactt ctaaattgct agaactctct tcttcatcga
    50221 ttccaaatat ataagctaat acaaaggtaa taacaaccga aatgaccgcc acaattaaag
    50281 catttacaat atttgatggc acatcagaat aaataaattg aggcaacgct atcaaagatg
    50341 ggacagcaaa tagatatgct ttaacactag taagacctgc aaataatccc gctaatccac
    50401 caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca tataatgcag
    50461 gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt tgttttgtat
    50521 tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct aagtttgacc
    50581 ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc aaaaaaatag
    50641 gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca ccaagaatag
    50701 ctaatgtaag ccatccagct acaccataca tttgcccaac tagatttgat aatccttcac
    50761 caacaattac tccaataggt ccgactacaa ctaaggcaat acagcttgat actaataata
    50821 ctagcgtagg ttgcaaaaaa ctcttagtaa tagctagtgt taatttagca attatttttt
    50881 caatatattt catcaaccaa accataataa gaattggaac gactgatgaa ccataactag
    50941 ctggtgtcac aggtgcacca aataaactaa gaggattccc tgattgcacc atttgaacaa
    51001 aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt acttttaatt
    51061 tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca tccccaaaaa
    51121 atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt ggtaaaatga
    51181 ttaccaagac tttcaacata cctcccccta acattgctgg aatgattgga gtcatggaac
    51241 cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga acaactgaat
    51301 cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca tcattaccaa
    51361 gtataatttg atattgtcca ttctttttca taatacctat tacacctggt atcttcttca
    51421 catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt gttacacaat
    51481 gggtaactct attgacattt ttttcacctc caattacatc gaggattttt tgtaccgtat
    51541 ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta agcgacgaat
    51601 atgagccatc aaataagcta attcactaga agtcagcaaa taattgtact ccgtttgtat
    51661 aaacattgct acctgttcac cacattcata ttctctagga tatttatttt tcattaatgc
    51721 taacaagtct tcatcatcat cgtcacaata agttgtattt tcaaccaagc gatgggcaaa
    51781 taattttata tgagttatga atctataata atcaataaaa tcttggttaa actcagtaca
    51841 atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt tatacgactc
    51901 ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg cagcttcgtc
    51961 aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt tcccaagttc
    52021 aaattcttct ttataatatt tcgatatttc ccagcgtagg ggattcgaaa taataatccc
    52081 ttctttataa cgttctatgc tcgaagaaat atgatccgtt aaattaatat agataatttc
    52141 atcaaaatta ttacccaatg ttattttacc taggttaatt attttttcgg tgatgtacac
    52201 caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatattat ctctattttt
    52261 gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccagttt ttcttccaaa
    52321 agctattccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg caattacggc
    52381 attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata aaaggaacct
    52441 acttaaaaac atcaagaaac ttcttctgat gtgattaaat aggttcctgc tcacttgtat
    52501 tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa ataattaata
    52561 actctgtaac cgtttttatt ttatgatatt tcaatctatt tgtcaagtac ttataaaaat
    52621 ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa gaaatgaaaa
    52681 tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag ttcagaaact
    52741 atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa taatggcatt
    52801 gcaccatacc aaacaatagt cttattcacc aaaagaatag gcgttactat ttttgattga
    52861 gtaaaagaca ctttaatttt ctggctcttc aactggtcta gccatgcttt atttgcaacc
    52921 gtctctggta tacatatctc aatttgacta atcctaaatt cttttagaaa attcatcagt
    52981 tttgtctggt gcacataagg taaaataagc agacattcct gtctttcccc tgctaagtcc
    53041 tctctcaaca ccttctcata tctactatca acataaacga attgtttctc ctcaccctca
    53101 atggcacgat aatccatctt tcgataagct acttgtcgtt tctgaaacat cttttctaaa
    53161 taaggaacat gaatatccac ataatcgaaa atacgcacca aagacttatc cttgtagttt
    53221 ctatgaatcc aacctgcata ctgaatcaaa ttatttttcc aagaaaaggg tgctgccaag
    53281 ataagcgtgt ccaactgagg taagtcaaaa ccttcgccaa tgtattttcc agtagacaac
    53341 aaaacaaacc ctttatctaa ctgttctaac gtctccagta aactcgttct ctctcggact
    53401 ttggtttttc cgctaataat gtaacagtca tcaacctctt tctctttcaa taatttttca
    53461 aagacatcta tctgttgaat tcgattaact aaaaccaaga tattccgtcc ttctgccact
    53521 tgggctagaa tatccttgag aatcatctga ttcctcactg agtcagtagc aatccaatca
    53581 ctaagctgta taaaattact tgctttggtc ttttcaattt ccaaatgacc aaaagaagtg
    53641 aatcttaatt gcaattgccg tttaaaatcc gtttccctct tatcagcagt atggagtatc
    53701 tcaccaattc tctgaaaaac aataggctca tgaccattct tacgctcagg cgtagccgtc
    53761 aaaccgtaaa gatacttccc tctaaactga gcaacaactt tttcaaacat caaggcagag
    53821 acatgatgac actcatccac aatcatcatc tcatactcat ccaaaagact ttgactattt
    53881 tccaacttaa atagagattg aatcataacg acatcaacca gtttactcag ccatttctta
    53941 gtcccaccgt actgcccaac atagccgatt accttttcac gacctgatgc cgtataacgg
    54001 atagcctcct cctcttcgaa agtcaaaaag cagtttaagc gatctagcca ttggtctaag
    54061 agttgcttat tatggactag aataattgtt tttgttttcc gttcagagat aagagcagca
    54121 cctaaaacgg tcttcccaaa accagtctcc gcatgaagta aaccattttc tttagaagtc
    54181 atatctgaca gggctaactc ttgctcaaaa gtgagttctc ccttaaattc cacgctaata
    54241 gacctttgta cctttctcct atcttccaca gatacctgct taaatttatc ttgcaatgga
    54301 tacagcaaac ctcttggcaa ccataaataa tgatcggatt ctccaaataa atacattctc
    54361 tcaggaattt gataggttgg ctgtcgcata gcctgcttta aatatagtaa aatgaaataa
    54421 taacaggaca aatcgatcag gaaagtcaaa tcgatttcta acaatgtttt agaagcagag
    54481 gtgtactatt ctagtttcaa tctactataa aattcgggat tagaaaagga agccatattt
    54541 ttcaagaaaa aagtgccttg gatgtcacag acgatttttc aagttggatc atattggata
    54601 aaacgacctt caactcctta tccaattctt gcttgcctaa ctcctcttgg attaacagtg
    54661 ccactttagc agttgaaatc ctctgaattt cttgtagata cctccattgg tcttcataag
    54721 gctgaaactg ttcatccaca aagaccgttc gcccttgatg gtaagcttct ccttgaaaag
    54781 gcaaggcaat caaatttcca aatcccccct taggaaggac atcctgattt ggaaacatgc
    54841 gatcaaaaga atcaaaggac agttgcatac tttcctgcat tgccaattct aatagtttct
    54901 ttccaaacag gcgagccttt cgactcagaa tcgcttcctc aaagaagaac caaatatgga
    54961 gtccgtaacc cgaacgagaa atctctaaat gggcttccat ctggcgttcc ctggctattc
    55021 ttcgaatggt taaaccagct tctttccaat ctccttcatc caaatccagt accaaaaaat
    55081 aacagctatc atctaagtgc ataggaaaga taccgatagc tgcctcccca cgaaaatgag
    55141 atttcaaaac ggaatccgtc aatgtctgga aactccgttt ttcaggtagc aactgcttcc
    55201 aaccataatc ataggaagga aaatactgaa ttttcccttg atcattgata aaactcttag
    55261 cataaacatc ataacggcca gcaaacacag aggtaaacaa ttgtaatttt tcttgcgtcg
    55321 tcaagcgact actttgaagt tggaacatct cctcgaactg agagcgttcc ataacaaact
    55381 gactcttgtc tttaagacgt ttacacaaga aaaactcact atccccatca aaagaagaaa
    55441 agacatcaag tacttctacc acaattccat ccaaagacac aaaaacagcc ataagagtca
    55501 cctccttgat tcctataggc tgattataac aagaatagct gaaattgtac acgaaaataa
    55561 aatcccttat ttgttacaat acctttgaaa acttttattt ctttgctacc cagccgatgg
    55621 catcgcttgg gggattttcg gtatcaatcc agataaattc aataccgatt tccccatttt
    55681 taaatttagt taaacgaata ccgttgattt ccagttcatt gagtcgttga cctgtcaaga
    55741 cttctcgttc tttcaactgg aaaagttaag gggggaacta atacaaatct tctaagcttc
    55801 tatattcaat gatttcattt ttgataatat tctttttaaa ctcaaaatgt tttaaaggat
    55861 tatcgattaa cactaacttt ggaatatcat ctagatttgt gaccaaggat aaaataaaat
    55921 ccgattgaaa ctccttgact ttttcaaatt cttttgcagt taaacgcaca cgccccttag
    55981 attttcggat accttttact tcggcaaggt aagaatactc ttggacatct acctgaaagt
    56041 catatccatc accataaaga cgggcatcgg ttaactgtcc accttggaat ttttcttctt
    56101 tatcaaaatg aaggataaaa taattctcag cctccattcc cgtttcctgt agacgtttga
    56161 atttagttcg aactattggt ttttcaacga tggttatgcc tgttttcttc ccttcactgg
    56221 caagtaacat tttaactatt tcagcataac tatgaacatc ttcatttcca aacatcatat
    56281 caattaaatc tttacgaaaa cgataaactt cagctttctg ccaccaacct tttcgattat
    56341 tgtcaaaata aggatcaaat aaatccattc tattttttac aactccagtt gtttcagcaa
    56401 ttcccagaga aaccacataa cgataaaact ccgacttgct agagcattga aattctttta
    56461 taaaaagctt gtcaaacttg gcaagaccgt agccaattaa atttaacaat tcataatgag
    56521 ggtgtttgga catcactttc tccatcaata gatattgatt tcattatacc aaaaaaacac
    56581 ggctcatcac cgtgtttctg tgtttattta acgagtttct tcatctcatc aatacgtgct
    56641 acggtcgcat catacttggc ttggtagtca gcttgtttgt cgcgttcttt ttggacgact
    56701 tctggtttgg cgttggctac gaagcgttcg ttagagagtt tcttaccaac catgtccagt
    56761 tctttttgcc atttagcgag ttctttgtcg agacgatcta gttcttcttc aacattgagg
    56821 agatcggcca gtggcaggta gatttctgct cctgtgatga cacttgacat agccagttca
    56881 ggtgcaggga tggttgatgc gatttccaaa tgttctggat ttgtaaagcg tttgatgtag
    56941 ttgacattgc tgttaaagaa ggcttccaag tcactatcgc tagtcttaac aaggattgta
    57001 ataggtttgc ttggtgctac atttacttcc gcacgcgcat tacgaacggc acggatcaag
    57061 tctttgagac tttctacacc agtgtgagcc gcaaggtctt caaaggctag attaacagtt
    57121 gggtatgcag ctgtcacgat agaaccttct gagatttgtc caaagatttc ctctgtcacg
    57181 aatggcatga ttgggtgaag gagacgaagg atcttgtcca gagtgtaaag gagaacagat
    57241 cgagtaatta ccttatcttc ttcattatcg ctataaagga cttccttggt caactcaaca
    57301 taccagtccg caaattcatc ccagatgaag ttgtagagga tgtggccagc aacaccaaac
    57361 tcaaacttat caaagttagc agttgctttt ccaatcgttt cattgaggtt gtggagaatc
    57421 cagcggtccg tcacattacc agcctcacct gttgcaactt ttgtgacatt gtcatgcgcc
    57481 acatccagcg tcaaacctcc attgttcatg aggatatagc gagaaatgtt ccaaatcttg
    57541 ttaataaagt tccatgaagc atccattttc tcataagaga aacgcacgtc ttgtcctggc
    57601 gcagaaccgt ttgaaaggaa ccatcgaagg gcatcggcac cgtatttctc gataacatcc
    57661 attgggtcaa tcccgttacc gagagactta gacatcttgc gtccttgctc gtcacgaata
    57721 agaccgtgga taaggacgtt ttggaatggt tgacggcctg tgaattccaa tgactggaag
    57781 atcatacgag acacccagaa gaagatgatg tcgtaacctg ttaccaaggt tgaagttggg
    57841 aaataacgtt taaagtcttc tgagtcgact tcaggccagc ccatggttga aaatggccag
    57901 agggcagaac tgaaccaagt atccaagacg tcttcgtcct gagtccatcc gtcaccttct
    57961 ggagcttctt cgccgacata catttcacca tcagcattgt accaggcagg gatttggtga
    58021 ccccaccaaa gctgacgaga gataacccag tcgtggacat tttccatcca ttgaaggaag
    58081 gtatcgttga aacgaggtgg gtagaattcg accttgtcct ctgtgtcttg gttggcaatg
    58141 gcgttcttag ccaattggtc catcttgacg aaccattgag tagacaagcg tggctcaact
    58201 acgacacctg tacgttctga gtgaccaaca ctgtggacac gtttttcgat tttgacaagg
    58261 gcaccgattt cttccaactt agcaacgact gccttacgag cttcaaaacg atccatgcct
    58321 gaaaattcaa aggcaagctc attcatagtt ccgtcgtcgt tcatgacgtt gacttgtggc
    58381 aagttatgac gttggccaac caagaagtca tttggatcgt gggcaggtgt gattttcacg
    58441 acaccagtac caaactcagg atctgcgtgc tcatctccaa cgattgggat gagtttatta
    58501 gcgattggaa ggatgacgtt tttaccaatc aagtccttgt agcgcgggtc ttctggatta
    58561 accgcaaccg caacgtcccc aaacatagtc tcaggacgag ttgtagcaac ttcaagggcg
    58621 cgtgaaccat cttccagcat gtaattcatg tggtagaagg caccttccac atccttgtga
    58681 atcacctcaa tatcagaaag ggctgtgcga gctgctgggt cccagttgat gataaactca
    58741 ccacggtaga tccagccttt cttgtaaagg ttcacaaaga ccttacgaac agcttttgac
    58801 aaaccttcgt caagagtgaa acgctcacga gaatagtcta cagagagccc catcttgccc
    58861 cattgttcct tgatggtagt ggcatattcg tctttccatt cccagacttt cgtcaagaaa
    58921 gactcacgac caaggtcata gcgggaaatg ccctcaccac gcaagcgctc ctcaacctta
    58981 gcctgagtgg caatccctgc gtggtccatc ccaggaagcc aaagggtatc aaaaccttgc
    59041 atgcgttttt gacggatgat aatatcttgc aaagttgtat cccaagcgtg accaaggtga
    59101 agtttacctg taacgtttgg tggtggaata acgattgaat aaggcttagc cttttgatcg
    59161 cctgaaggct tgaaaacatc ggcatcaagc catttttggt aacgaccagc ctcaacctcg
    59221 gctggattgt atttagatga aagttcttta gacatgtgtg ttctccttaa ttacttttat
    59281 tgacaatttt aaccaaacca atttttgaaa gttcaatata aatctcttca atttcagcaa
    59341 atgctgcaag tggtgacata gtataatttc caggattata tttaagatca tacttgctta
    59401 tctttgaaat ataataccta gagtgtttca attttaatga ttccaacttt gatttaatat
    59461 ctactaatgt attatggttt aactttaaaa acaacttatt ataattacca tagagctctg
    59521 taagagcatt aaagtattct ttcactagag ctatagcgtc aatcttagat gtttcttggt
    59581 ttagttttat caactcccct ttcaattttt tccatttaaa gttggaattt aaaagataat
    59641 ctaaatcaat atagaaatct attataacag tctcatcatc tgggctaaca gcttttacct
    59701 catttattgg taagtcagta tgttgcgaat aatttctcaa agaatggcaa aatcgataag
    59761 caaaattggt atcatactga tagcttgcaa aaccatgtat acaatcaaac tcctcactat
    59821 ctttggaata tttttgttta atttggtttt cgttaaaatc gacaaacaat tttccactgg
    59881 ataataaatg aatcatgaaa cgatttacat ctgcctcttc aatttctaat tcctttgact
    59941 caagtttatt tttaatactt aaaaaatccg agacatctga aataaacaat tcgaacatat
    60001 tcttgatttt ttgaaaattc ttttgaatct caaaaatttg gtccgatact gacattattt
    60061 ccttggttgg ttcaatatca gagatgacaa tacgtttttc attgttgtta atttctaaat
    60121 aagctaatcg ctcgataata tcactatcat ttaattcagc atactcaaca tcaatttggc
    60181 gtaactgctt ctcagataga gagcttactt cctcttttac atcgctcatc ttattcctcc
    60241 cactcgctct tcagcaagcc atatatcaga ctgtcacagc ggtttccttg aacatccttt
    60301 cggtctctta tgcgagcttc gagggtaaag ccaagctttt ccgagactcg ttgactttga
    60361 aggttatatc caaagcaagt tagttcaatc ttgtgaagac caagttcttt aaaagctaga
    60421 tcaatcaagg cacacgctgc ttctggaaca taacctcgcc cccaatagtc tgggtgtaag
    60481 gtatagccga tttccagcac atcatcttca tggcgatggt tgaaatcgac agagccaacg
    60541 atcttatccg ttcctttgac gacaatcccg tagcctgctg ggagattttc cttttgatta
    60601 cgctccggaa gaatgtgctc cagataataa atctcatctt ccaaggtctt gactggagga
    60661 aaacctgctg gataggcaac ctctggcaaa ctagcatagt caaagatatc ctcagcatcc
    60721 gccacagtac ggactcgtaa aacgagacgt tctgtttcga ttttatctgg cagctcagtt
    60781 cttgccatcc ttcttcctcg cttttttgat gaaactgccc ttcatatcta cacgcttgtc
    60841 cagatagcga taaacgcgct gatatccatc tcccatgaaa taggttgggg caaacagttg
    60901 atttttaaaa tgtccctttt catccaggag ttctggaaca acaagtcgct caagaatctt
    60961 ggcaaagatg tggcaaatac cgtcttcctc aacaatccta tctacccgac aatctaaaac
    61021 aagtggacag gcgtctaaaa taggagtctg agttcattca gaaatttcat aatgcactcc
    61081 caaacgttcc aatttctcct gatgactgat aaaaccagcc tgctccatcg caagcataga
    61141 agtttcatca gaaatattca cagtaaattt ttgatactgt ttgatctgct ctgcggcatt
    61201 ctctcttgca acgactccaa tcacaaccca atctcctaga ctataagagg aactacaggt
    61261 cgtgatgtta tagccaaaat tctaatcttg atatcctaaa ataaaaacag gaaaaccata
    61321 atatagttta cttgtgttaa aagattgctt cataacaacc ccctttgact aagacgtaaa
    61381 agaaaagccc tgccatctac atgacaggga cgaatgtgtt tatccgcggt accacccaat
    61441 ttcgggcagt tgcccgcaac tctcgtcttt aaagcaaaaa gacactttta tttcaatttt
    61501 tcatccatta gcaaccagtt ttgacacatt tgtggacttc tcagcgccgc cactttctgt
    61561 aaaatgtggg attcaaaaca cctctaatgg ctctattgta gcaagatttt ttcggaaatg
    61621 caaggctcaa gaaaaattac ttgaacttga tgccattttc tttcaatttc ttgatggtag
    61681 ctgggccgat tcctttcaag gcaaggagtt ctttttcagt ccagtttttg aaatctgaag
    61741 cagacttgat tccttcatca tagaaagtct tggcacgatc aagtggaagt ccacccaaat
    61801 ttgctgcaaa atcttctaca gaattagcta ctttttgagc ttgctctttg gtagcttcta
    61861 ctgcttgttc aactttttta gaaacagcct taccagctgc gcttgctgac tgttctgcac
    61921 gcttcacgac tttttttgtc tcatctacaa ccttagtcac agtacttgaa aaggcacctg
    61981 cgcgacggag gccatttcgt aattgttttt tacgattgag tttctttgac atgataaaat
    62041 cctttcaata aaaaatccct gctctgacaa ggatttaaca taaacattct atcaagattt
    62101 tagtgaaaaa tcaagaatct ttctcgttta ataatttcgc tcaccaaaca agccttctgg
    62161 caaatcatgg aatcccttgc ctgctttgaa gttttcaaac ttaccaagca agaactgata
    62221 agcatccaag cgactctcgt agcgaatcat ggcatctttg gcacgctcgt cctggtcttc
    62281 ttcgtaaact ttttgacttt ccttgtgcgc catatcgtta atcatgattt gggtattgac
    62341 ccaagcttca aattccttca taaattcttg ttcgtaactc attttttctc cttattctaa
    62401 tccacgaaaa tagtccgtat caatctcacg gtagggctgg atatcctgaa catactccaa
    62461 cactccttgg aattctccgt cttcatcgtg tactgcagca taggtgatgt ggacaaactt
    62521 acctcgcgac tcagacttga accacatttc atacttgtct ttgcttccct cacgaagccc
    62581 cttcatgata gttttgacct tgtccaagta cttaggcgga tggcagagtt cgacattgcg
    62641 cccgacttgg gacggcgtcc gtttgaaaat catctcatca gctggcgtat tgtcattgta
    62701 atactggaaa atatcttctt tattgacaaa ggtaatctcc atagggagat gattgaggat
    62761 gagattggcc tgctcgactg aaagatagcc attaccaaaa gcctgttgac tatggcggtc
    62821 cagcacagct tccttttcct taggggtaaa ggtaatggta aaatggcctt ctggcgtatc
    62881 tatgacttgt tgaacttgac cttctgccgt atctagctgt acaggctcct ctgcaatctt
    62941 ttcctcaata aagctctgtc gttctggcac ccatttctct gacggacgga tgatggcata
    63001 gccataggca tcgctctcct ccgcaatctg aagccagtca tcctgagtaa aagactcaag
    63061 gagaatcatg aggaggatgg actcttcctt gaaaatcata ctttcaaact ctgtcgcaaa
    63121 agcttcaaaa gcttccttta cactgctaat tgacacttct ggtagtgact tggctgtcgt
    63181 tagagctgtt tgaaagagtt ccctaatctg atcatccact ccccacataa ctttgggagg
    63241 tgaatcgtgt ccatagcgct ccatgatagg aaagaagagt tcttccttac gttggtaatg
    63301 gatgtcaaat tgacccacaa gtcccatctg acgcaccaaa cccttacgca tctccgccag
    63361 catttcctcg tcttccatag actcataggt atctaacaat ctacgaatgc gaatcaaggc
    63421 cgcacggaga gccagatttt cttctttgaa gacacgaact gggtgacctg gatgctcagt
    63481 atctgaaact tcgacacctt tgatagcatt tttaaaaaga ttggcatgga catcacagag
    63541 ttccataaca tcttcaaaag tgacgcccga atccgagttc atcagctcgt gctccataag
    63601 ggaaatctcg atggctgaca cgcccgtaaa ggtcgcatca aagcgatctt gaaccgactc
    63661 aggagaggcg ccattgtgca attctaacaa aatatcccgt aggatatgaa tccgttcatc
    63721 tgtcattagt ctaatccaat cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg
    63781 tccataggag ttcctgctag cttagaaccc tgtttaagtg atactttacg accaactgta
    63841 ttgcgcatta agggattggc aaggggttta aaacccaact ccactagaat ttccaagact
    63901 tctggatgct tgtccaccac ttctgcaaca ggaattgaca catcgatgat attgtccatg
    63961 acgacctcca ttgtatgttc taatactcaa tgaaaatcaa agagcaaact aggaagctag
    64021 ccgcaggttg ctcaaaacag tgttttgagg ttgtagatag aactgacgaa gtcagctcaa
    64081 aacaccgttt tgaggttgtg gatagaactg acgaagtcag taacatatat actgcaaggt
    64141 gaagctgacg tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt
    64201 ataccatatg gaaagagaat aaaaaactag cagtggagtt cctgctagtt ctctgcaact
    64261 tggattacca tctagataag tttaaagaac caatccaata tcttgtaaaa cagcaattga
    64321 actgcaaaag aaatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa
    64381 agaatagcaa gaagaccaaa aaaatttcat tctctctcct ctggcttaat gagccaccga
    64441 gccgtatcca ttagcttatc tgcaataaaa agtttgccca gaccaacaac gacatggtca
    64501 gctttcttta tcgttttcat cacttttaca ccttgcacgg tcaaaaagta attaccataa
    64561 attttagcaa aagctttgat aggattcata ttactctcct ttgatgattt cagcctcttt
    64621 tcggattgtt tcaacatctt cttgatattg aacttcacta tagttgacta gcttggataa
    64681 ttctttctgc aagctttccc ccattggttt catagttgca aaggttaaac cacctgaaat
    64741 gataccaccc aagataggaa taaatttccc tattcctttg gccagccctc ccttggtaag
    64801 attcacacca aatattttta agactttttt caaaataggg taccaaagcg tctttgttaa
    64861 agctttatta ggcactgttt tcattacctg tttggcaatt gttataccac cagcacgtag
    64921 caaagcagcg gttccattca cccctaacat tacgcctaga taaagcaaga gggtattttg
    64981 agcatcttca ctcaactcct cgcgtgaagc ccaaagatcc tcataaccat aaatataacc
    65041 taattcttga gccaatttca gagagaaagc ataaaattga gccacatcag ctggaatggt
    65101 aattgccata gcaagccctc caggtaatcc tgccaaaaca gaagtcccac tcgctaataa
    65161 tacattgtcc cgaatacaag cattagctac acgatctaat atttcttgag atagaagagt
    65221 cgttgggtct tgttccaata aggtaggaat atcttttgga tccaattctt tggaaaactt
    65281 atccactaaa aatttcgaac gatcaacctt aacaacaggt agtttcacca cttgttgcaa
    65341 tacttgcata gctaagtctt gttcagccat atacaaactc cttatttctt ttttgcacct
    65401 tatcatatta tatttcctac aaaaaaagca ttttctaatt agataacatt aaaaaataca
    65461 gaaccccttt t
//
LOCUS       DBERAE010000007        50549 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.07, whole genome shotgun sequence.
ACCESSION   DBERAE010000007 DBERAE010000000
VERSION     DBERAE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.07"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            5..75
                     /locus_tag="ACL70N_000561"
     tRNA            5..75
                     /locus_tag="ACL70N_000561"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="ACL70N_000562"
     tRNA            110..183
                     /locus_tag="ACL70N_000562"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            267..356
                     /locus_tag="ACL70N_000563"
     tRNA            267..356
                     /locus_tag="ACL70N_000563"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:303..305,aa:Ser,seq:tga)
     gene            367..440
                     /locus_tag="ACL70N_000564"
     tRNA            367..440
                     /locus_tag="ACL70N_000564"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:401..403,aa:Met,seq:cat)
     gene            444..516
                     /locus_tag="ACL70N_000565"
     tRNA            444..516
                     /locus_tag="ACL70N_000565"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:477..479,aa:Phe,seq:gaa)
     gene            529..609
                     /locus_tag="ACL70N_000566"
     tRNA            529..609
                     /locus_tag="ACL70N_000566"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:563..565,aa:Tyr,seq:gta)
     gene            614..684
                     /locus_tag="ACL70N_000567"
     tRNA            614..684
                     /locus_tag="ACL70N_000567"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:646..648,aa:Trp,seq:cca)
     gene            699..771
                     /locus_tag="ACL70N_000568"
     tRNA            699..771
                     /locus_tag="ACL70N_000568"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:732..734,aa:His,seq:gtg)
     gene            782..853
                     /locus_tag="ACL70N_000569"
     tRNA            782..853
                     /locus_tag="ACL70N_000569"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:814..816,aa:Gln,seq:ttg)
     gene            863..946
                     /locus_tag="ACL70N_000570"
     tRNA            863..946
                     /locus_tag="ACL70N_000570"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:897..899,aa:Leu,seq:caa)
     gene            complement(1057..1788)
                     /locus_tag="ACL70N_000571"
     CDS             complement(1057..1788)
                     /locus_tag="ACL70N_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS0589407.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1781..2017)
                     /gene="relB"
                     /locus_tag="ACL70N_000572"
     CDS             complement(1781..2017)
                     /gene="relB"
                     /locus_tag="ACL70N_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS0589408.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKATSHEEMMRRYG"
     gene            complement(2233..2670)
                     /locus_tag="ACL70N_000573"
     CDS             complement(2233..2670)
                     /locus_tag="ACL70N_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS0589409.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2711..3844)
                     /locus_tag="ACL70N_000574"
     CDS             complement(2711..3844)
                     /locus_tag="ACL70N_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0589410.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAETRRIVINKKLSQELQDWKKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3848..4051)
                     /locus_tag="ACL70N_000575"
     CDS             complement(3848..4051)
                     /locus_tag="ACL70N_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HGS0589411.1"
                     /translation="MIATVTKNDLIALGFFEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLVFDVQNSTLKE"
     gene            complement(4065..4847)
                     /locus_tag="ACL70N_000576"
     CDS             complement(4065..4847)
                     /locus_tag="ACL70N_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HGS0589412.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDSLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVWINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKYGQYFDNHVKYKKIRLDE"
     gene            complement(5031..5804)
                     /locus_tag="ACL70N_000577"
     CDS             complement(5031..5804)
                     /locus_tag="ACL70N_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0589413.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQIAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEYEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTNWATDETLKQLSKPQI"
     gene            complement(5848..6618)
                     /locus_tag="ACL70N_000578"
     CDS             complement(5848..6618)
                     /locus_tag="ACL70N_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS0589414.1"
                     /translation="MAIYYSVSDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDYGS
                     QSFQVISKIIELEKIYPKQIITLFGNHEEWFYDWLILDNPTASAFPETIKSFFSTEEL
                     NYILKTNPNNFETGVRNEIRNNDKYIPFINWFQKRYEDSRYFETENQIFVHAGIDEEA
                     NNLWKDLTSPEIFTNKFPITTGRFYKDIISGHFASWEVAKDKSYLGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVKKSYQYSKNTSLLPKKFDRA"
     gene            complement(6637..7026)
                     /locus_tag="ACL70N_000579"
     CDS             complement(6637..7026)
                     /locus_tag="ACL70N_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589415.1"
                     /translation="MQIFTYNDFLKDKEIVTFEQAEIILDELIKSSNIYDPEFQAYWK
                     ELIEYSAKYAEMRGKWRILTKEEQDTLDDTRTNIHNRIRDNLISIRGLAQINNKDTSW
                     FDKFHNDRKRMGDFANYINYIYAVNSR"
     gene            complement(7064..7378)
                     /locus_tag="ACL70N_000580"
     CDS             complement(7064..7378)
                     /locus_tag="ACL70N_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589416.1"
                     /translation="MKLNDFLKPELLGNKFIAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQVKVNTLSPTASVQEMANNKTCPVTLKDLNVGQYNGNLWFSCSNVILI
                     TK"
     gene            complement(7468..8790)
                     /locus_tag="ACL70N_000581"
     CDS             complement(7468..8790)
                     /locus_tag="ACL70N_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGS0589417.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTSKDGS
                     GYEKIVRSAVLEYEIDRQKGHVLIKALITGDEFSKKVQSLDDVLSDVLELELEEKIIR
                     PSFIEYHFYYIKPKRLVLQSHSQRQEIDSLDIDLGYGVNYNPVKCSHILVSGGTGSGK
                     SVLISVLILEFLKRQSTVYIADPKNSDLGSLSHYFGNKYVATTPNNIARIVRVVVEEM
                     QERYQVMRDNFQYGSNFTNHGFKPVWLIFDEMGAFQATGSDKKSREIITEVMDGIKQI
                     ILLGRQSGIFILVSAQQVNASTTLSTELRDNLGLRIALGANSSEGYHMVFGSATPDKL
                     KPIEEKGSGYLYIQGSGKESAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(8796..9014)
                     /locus_tag="ACL70N_000582"
     CDS             complement(8796..9014)
                     /locus_tag="ACL70N_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589418.1"
                     /translation="MSDNLKAYLFLLGFVILAGIAIFIFPQGHFFSNSILILGCIPLL
                     ISTYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(9054..9809)
                     /locus_tag="ACL70N_000583"
     CDS             complement(9054..9809)
                     /locus_tag="ACL70N_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0589419.1"
                     /translation="MIQLTASTWNINLRSRKGKQIPEMIAQELAQQNSDIICLTEYVK
                     TDNHSQFCSSLQTNGYTIFEDVRTIDFGNEILIAIKSDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKIGGENVFEDFKHRKTQLDKLIFNLPIHENTIILGDFNNG
                     FFKQNDDTHSYQGKPREFYSYPLLKSEMNKAGLTVHTPSEENSWKYCKLDHIIGNIPI
                     SNVCYSWRFLENPDYQNKVGFPDHAILSATISL"
     gene            complement(10237..10740)
                     /locus_tag="ACL70N_000584"
     CDS             complement(10237..10740)
                     /locus_tag="ACL70N_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589420.1"
                     /translation="MTQFQVRISGEAAYYLRMLKEKYETSEGINITKATILTRAFQNS
                     KTVTNWTKVVQDNSISLKNIYPVEEKELKLNVALSDEVAEGIKKYKEILPSATNTQSV
                     TLGVCVKFLLKAELMTQLNHDISEPEKDFDKKFSILEKQLLEIVAPVNHKLLSDTIWN
                     FKNNFIK"
     gene            11169..12446
                     /locus_tag="ACL70N_000585"
     CDS             11169..12446
                     /locus_tag="ACL70N_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGS0589421.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKIDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            12522..14006
                     /gene="thrC"
                     /locus_tag="ACL70N_000586"
     CDS             12522..14006
                     /gene="thrC"
                     /locus_tag="ACL70N_000586"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGS0589422.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGETVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLYEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            14067..15347
                     /locus_tag="ACL70N_000587"
     CDS             14067..15347
                     /locus_tag="ACL70N_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS0589423.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            15351..15971
                     /locus_tag="ACL70N_000588"
     CDS             15351..15971
                     /locus_tag="ACL70N_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0589424.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADISRIFETK"
     gene            16137..17315
                     /locus_tag="ACL70N_000589"
     CDS             16137..17315
                     /locus_tag="ACL70N_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS0589425.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVAPSTGTSVPEEQTAETTRPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            17743..18166
                     /locus_tag="ACL70N_000590"
                     /pseudo
     CDS             17743..18166
                     /locus_tag="ACL70N_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            18177..18545
                     /locus_tag="ACL70N_000591"
     CDS             18177..18545
                     /locus_tag="ACL70N_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGS0589426.1"
                     /translation="MSIITIILTTIVAWEHFYIFYLESIATQSDATSRVFNMEREELA
                     HPSVSLLFKNQGIYKALLGVCLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            18652..19270
                     /locus_tag="ACL70N_000592"
                     /pseudo
     CDS             18652..19270
                     /locus_tag="ACL70N_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(19298..20155)
                     /locus_tag="ACL70N_000593"
     CDS             complement(19298..20155)
                     /locus_tag="ACL70N_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGS0589427.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            20285..21427
                     /gene="tgt"
                     /locus_tag="ACL70N_000594"
     CDS             20285..21427
                     /gene="tgt"
                     /locus_tag="ACL70N_000594"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGS0589428.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            21528..23345
                     /locus_tag="ACL70N_000595"
     CDS             21528..23345
                     /locus_tag="ACL70N_000595"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS0589429.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            23498..24649
                     /gene="nagA"
                     /locus_tag="ACL70N_000596"
     CDS             23498..24649
                     /gene="nagA"
                     /locus_tag="ACL70N_000596"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGS0589430.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            24812..25870
                     /locus_tag="ACL70N_000597"
     CDS             24812..25870
                     /locus_tag="ACL70N_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS0589431.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            26021..26386
                     /locus_tag="ACL70N_000598"
     CDS             26021..26386
                     /locus_tag="ACL70N_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGS0589432.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            26462..27403
                     /gene="comGA"
                     /locus_tag="ACL70N_000599"
     CDS             26462..27403
                     /gene="comGA"
                     /locus_tag="ACL70N_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGS0589433.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            27351..28367
                     /gene="comGB"
                     /locus_tag="ACL70N_000600"
     CDS             27351..28367
                     /gene="comGB"
                     /locus_tag="ACL70N_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGS0589434.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            28369..28695
                     /gene="comGC"
                     /locus_tag="ACL70N_000601"
     CDS             28369..28695
                     /gene="comGC"
                     /locus_tag="ACL70N_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGS0589435.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            28688..29092
                     /gene="comGD"
                     /locus_tag="ACL70N_000602"
     CDS             28688..29092
                     /gene="comGD"
                     /locus_tag="ACL70N_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGS0589436.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            29055..29357
                     /gene="comGE"
                     /locus_tag="ACL70N_000603"
     CDS             29055..29357
                     /gene="comGE"
                     /locus_tag="ACL70N_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGS0589437.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            29320..29781
                     /gene="comGF"
                     /locus_tag="ACL70N_000604"
     CDS             29320..29781
                     /gene="comGF"
                     /locus_tag="ACL70N_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGS0589438.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            29759..30205
                     /gene="comGG"
                     /locus_tag="ACL70N_000605"
     CDS             29759..30205
                     /gene="comGG"
                     /locus_tag="ACL70N_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGS0589439.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            30308..30902
                     /locus_tag="ACL70N_000606"
                     /pseudo
     CDS             30308..30902
                     /locus_tag="ACL70N_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            30963..31916
                     /locus_tag="ACL70N_000607"
     CDS             30963..31916
                     /locus_tag="ACL70N_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0589440.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            31967..33157
                     /locus_tag="ACL70N_000608"
     CDS             31967..33157
                     /locus_tag="ACL70N_000608"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGS0589441.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADVIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            33158..33289
                     /locus_tag="ACL70N_000609"
     CDS             33158..33289
                     /locus_tag="ACL70N_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589442.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            33306..33677
                     /gene="rnpA"
                     /locus_tag="ACL70N_000610"
     CDS             33306..33677
                     /gene="rnpA"
                     /locus_tag="ACL70N_000610"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGS0589443.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            33652..34476
                     /locus_tag="ACL70N_000611"
     CDS             33652..34476
                     /locus_tag="ACL70N_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS0589444.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            34495..35481
                     /gene="jag"
                     /locus_tag="ACL70N_000612"
     CDS             34495..35481
                     /gene="jag"
                     /locus_tag="ACL70N_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGS0589445.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            35532..36155
                     /locus_tag="ACL70N_000613"
     CDS             35532..36155
                     /locus_tag="ACL70N_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGS0589446.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            36286..37743
                     /locus_tag="ACL70N_000614"
     CDS             36286..37743
                     /locus_tag="ACL70N_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0589447.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            37766..38047
                     /locus_tag="ACL70N_000615"
     CDS             37766..38047
                     /locus_tag="ACL70N_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0589448.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            38124..38609
                     /locus_tag="ACL70N_000616"
     CDS             38124..38609
                     /locus_tag="ACL70N_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0589449.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            38626..39291
                     /locus_tag="ACL70N_000617"
     CDS             38626..39291
                     /locus_tag="ACL70N_000617"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGS0589450.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            39295..40158
                     /locus_tag="ACL70N_000618"
     CDS             39295..40158
                     /locus_tag="ACL70N_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGS0589451.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            40160..40864
                     /locus_tag="ACL70N_000619"
     CDS             40160..40864
                     /locus_tag="ACL70N_000619"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGS0589452.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            41043..42716
                     /locus_tag="ACL70N_000620"
     CDS             41043..42716
                     /locus_tag="ACL70N_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0589453.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            42828..43919
                     /gene="ulaG"
                     /locus_tag="ACL70N_000621"
     CDS             42828..43919
                     /gene="ulaG"
                     /locus_tag="ACL70N_000621"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGS0589454.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            44033..46009
                     /gene="tkt"
                     /locus_tag="ACL70N_000622"
     CDS             44033..46009
                     /gene="tkt"
                     /locus_tag="ACL70N_000622"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS0589455.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGINTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            46126..46425
                     /gene="yajC"
                     /locus_tag="ACL70N_000623"
     CDS             46126..46425
                     /gene="yajC"
                     /locus_tag="ACL70N_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS0589456.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            46472..46900
                     /locus_tag="ACL70N_000624"
     CDS             46472..46900
                     /locus_tag="ACL70N_000624"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGS0589457.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            46902..47312
                     /locus_tag="ACL70N_000625"
     CDS             46902..47312
                     /locus_tag="ACL70N_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGS0589458.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            47612..50263
                     /gene="adhE"
                     /locus_tag="ACL70N_000626"
                     /gene_synonym="adhC"
     CDS             47612..50263
                     /gene="adhE"
                     /locus_tag="ACL70N_000626"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGS0589459.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSVHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        15397 a         8878 c        10661 g        15613 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaaac tattttggag gattacccaa gtccggctga agggaacggt
      301 cttgaaaacc gtcaggcgtg taaaagcgtg cgtgggttcg aatcccacat cctcctttta
      361 tattaacgcg ggatggagca gctaggtagc tcgtcgggct cataacccga aggtcgtagg
      421 ttcaaatcct gctcccgcaa taaggctcgg tagctcagtt ggtagagcaa tggattgaag
      481 ctccatgtgt cggcggttcg attccgtctc gcgccattta tatattttgg aagggtagcg
      541 aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg gttcgggggt tcgaatccct
      601 ccccttccat tttacgggca tagtttaaag gtagaactaa ggtctccaaa accttcagtg
      661 tgggttcaat tcctactgcc cgtgttaata gaattatggc gggtgtggtg aagtggttaa
      721 cacaccagat tgtggctctg gcatgcgtgg gttcgatccc catcactcgc ctattttata
      781 ttggggtata gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat
      841 ccagctaccc cagttactat ttgccggcgt ggcggaattg gcagacgcgc tggactcaaa
      901 atccagtgtc cgcaaggacg tgccggttcg accccggccg ccggtatagt attaaagaca
      961 aggttttagg accttgtctt tttgttatgt cataagaaat ttcttggaat tgttactaat
     1021 aattactaat ttcatataaa agcacatgat taaaagttat agaaagtgat atttttgggt
     1081 aattgtatca tagtaaagaa caggtattgt tttgctattc gttacatctc catcaattaa
     1141 gtaatgactt ttactatcat agtaaatctt acctaggtat cttctatctt tagctacttc
     1201 ccaagaagca atatggcccg aaataatagc tttatgaaat ctaccagtgg taattggaaa
     1261 tttgtttgta aatatctttg aactcgttag ttctttccaa agcattcctg cttcttcatc
     1321 aatgcctgca tgaacaaaaa tttgggtatc agtttcataa tagcgtttat ccctatatcg
     1381 ctttttaaac cagtttataa atgggttgaa tttgatatta tttttaattt catttctaac
     1441 acctgtttca aagttgttag cattcgattt aaaaatatag ttcaattcct ctggagagaa
     1501 gaagcttttt attgtttctg gaaatgctga agcagtaggt ttatctaaaa tcaaccaatc
     1561 ataaaaccat tcttcatgat tccctagaag agtaataatt tgattaggat aaacctcctc
     1621 aagttcgatt attttggaaa tgacttgaaa agattgaagt ccattatcaa gataatctcc
     1681 tagtaaaaat aggcgattat ctttatcgtt taaatttact ttattgagag cgtctctgaa
     1741 ttcatccaag tatccatgta tatcagatat tgcgtataat ttagccatag cgtctcatca
     1801 tttcttcatg tgaggtagct tttttgccac attcaaccca ttttttataa gcttcatcag
     1861 cgaccttaat atcatacata tcttcaattt tctctataac agcttgtcta ataaagtcag
     1921 tctttgttgt attattttct tcaacaatag catttaataa agaatttaac tcttgactaa
     1981 gttgaataga aatttgtgta gtaacaacat tattcatata acagccacct aatagttatt
     2041 ttagatacat tatactccta gtctaaaagt ttctcaataa aaaatttcac tttttatagt
     2101 tatttatttt aataaaattg tagtatctgc aaggatgtgc cagttcgaga ccgaccgcca
     2161 gtatagtaat aaagacaaag tttataagcc ttgtcttttg ttttctcttt ataaaatttt
     2221 atagtttagt tactaacttt ttttctttgc tcttaaaaat ctaatagcag aactgtattt
     2281 cttatttctc tctaagtctt tttcagtaat taatggtagt cttgttaaat ctgaattatg
     2341 ccgtaaatcc gccaacttta caactctagc gagttcattt ttctttacta gattgagata
     2401 agattgataa tcttgtcctt ttttctttgt gagtatatcg acggcttcta taatgttttt
     2461 tgaaaaacct tcctttttta ggtctagtag ggttagtgaa gtatcttcaa ttacatcatg
     2521 tagataggcg acagctttct cttcatcagt tgcgacaaaa ctagctactg tttcagggtg
     2581 tttaatgtag tcaattcctg ctctatcaat ttgtccaaag tgtgcttttt tagctacttc
     2641 atgtgctttt attacttgtg atgtatccat gatttaatta taaactttcc atttataaaa
     2701 ctcaattact ttatagtaaa tcatctagtt tatcagctaa atccttttgc ttacttgggt
     2761 acaagtgaga gtaggtatca atcgtggttg ttatagaagc atgtcctagt cgctctttta
     2821 caactagata atcttcccct tggttaatca gcagggaagc gtgtgagtgc ctaaaatcgt
     2881 gtatgcgtat cttttttagt gtgctatcac gttcaatgat tttcttgtac tgcttttcaa
     2941 tagcattttt tgtaattgtg ataggactat tttgaaacac ttgtaatgtt aggctattgt
     3001 tggtaaattg ctctaataga tgtttttgtc gctttttcca atcttgtaat tcttggctta
     3061 attttttatt gataacaatt cttcttgttt ctgctttagt ttttgttgtg ctgatatgag
     3121 ttactccttt attaacatag acagacttcg tgatatgaat tgtattactt gaaaagtcga
     3181 tgtcttgcca tgttagggca agagcttccc caagtcttaa tcctgtaaag aatagaacag
     3241 taaagagtag tttgatattg tattcttcgg gttcaaatag tgtcaaaaac ttctgaaatt
     3301 ctttgactgt ccaaaattgc atttttgttt tttcaattgg caactttttt attaattttg
     3361 ctggattgga ggagtaatag ccttttcgca aaccaacatc aaaaattttt ttgagtaaaa
     3421 tcatgatttt gttaatagta tttgtgctta acggtttatc agaattttta gctacttttt
     3481 gcctaagatg ttctctaaat tggtagatgt cttcataggt tagttttccg acattatcga
     3541 ccatagaaaa ataatctttg atgtgtttgt tgtaattatt atcttgtgta ttgatatagc
     3601 ttgcttttcg atgatttata ctatcttcct ccttaagtag ttcatatagt atggggatag
     3661 ttattttagc tccataaaag cgttctttta actctacact tcgtaagtag tgttctgctt
     3721 caatagcttc ttttttcgtc ttatagccct ttctgacaag tctacgttgc tttagtgtta
     3781 ttgggtcaaa accgttgcta atatcaacta cccaattacc gtctttacct tttctaattg
     3841 ccatatttta ctccttgagg gtactgtttt gaacatcaaa aacgagtaat tcggtagcaa
     3901 tagtagcagg tatagtacca attcgcttgt tctgatagac tgtaaagcct cgggttatca
     3961 gtagctcttt cccttggcgg ataatacgtt tagatgttcc ctcaaagaaa ccgagggcaa
     4021 ttaggtcatt cttagtaaca gttgctatca tgtgacttac tcctttattc atctagtctt
     4081 attttcttgt actttacatg attatcgaaa tactgaccgt atttatagac cttactagtg
     4141 tattccgttt catatagcac gactgaacta tcatagttaa aatcttcata agtgtaaaat
     4201 ttatcttcat caggcttttt caagttgcgt gatgaaaaat aggcttgctt tccgaagttt
     4261 tccaacaatt cttgtccaat acctttttca aaatactttg tgacatatcg accgcgattt
     4321 tctttgctgt cgacgtcaac tttatttatc catactgcac catgccccca aagttctaat
     4381 aattgcttat gtggaatata gggaacactg aatagcaaaa tatgactatg ccatgcttta
     4441 cgtttttgcc tctctaatac tgctatatat tttaatttac ttttcttggt attaaaaatg
     4501 tggtagttaa agcgtttaat aaatgttttg agtgagtctt tgaagtggtt tctatcgctg
     4561 atattttcct tagtggtcag tgtaagaaaa gaagttgtat catcaaaatt acaatcaact
     4621 agacggagta agttccactt ggcttctaag cgagtcttct tcatacgttc aagacgttgt
     4681 tcttgttcta ggggtgttag ttcatcaaat gttctgcgtt ttgctttttc cttgttttca
     4741 gtattagtat ctaaaataga ttttcctttt gaaaatattg gcttttcata ttcccaaatt
     4801 tcaatatagg aagaagtgcg gactattttt ttattatatg aggtcataaa aaatagttcc
     4861 ttttaggttg gctttcgcca aaagattgtc tatataataa ataaactagg aggagcaaag
     4921 ctcctccaca cttctatcat gtgtttctaa gcatcgctcc gctaaacacg cttccagctt
     4981 gctgacctcc agtcagcagt ttcgcttagt cacatgatga gaagtagtag ttaaatttgt
     5041 ggtttagata attgttttaa tgtttcgtct gtagcccagt tggttgaaat gatttcaaga
     5101 tggccttggt catagactag caaatctccg ttaccaataa attgatattt attatctttg
     5161 tcaatatata atgaaaaagt atctatacca ataacatttt tagaaatatc aatagattct
     5221 ttaggggtat gtccaacaat ttgtttagga aagtcttggt tgggaagcaa ttctaattct
     5281 ctaaaatgtg cccataaagg agaaccccca agagctttcc caccacgcat tggtcctatt
     5341 gtataagcta ggatatctaa ttcttcttca tactctttgg tataaaggtt aaaatgccat
     5401 tcttttgggt caaatatcag attgaaacca gcgtgactga ctaaataatc atctagttga
     5461 taagctattt gtaatttcaa atcctgcaac aattctttta ctgcgaaaaa cacttctaaa
     5521 ttttgaattg agaaaggagc ttgttctccc agtaaataat aagcatcatg attacctata
     5581 agattaatta catctattcc gttttgctct ttatctattt tccaagagta taaaaaagtg
     5641 aggtctttgg cataaagttg gatattgtta gtttgaccat gtaaatcaac ataatcacca
     5701 agaaaaatga ttctcttaat gttatgtgtt tggataattt tgtcaacaat gggtaaaatt
     5761 agttgagatt ttaaatgtaa gtcaccaatt aataatgtct tcatatatat tcccctcttt
     5821 atttttgata ttagtctaag aatagaatta agctctatca aattttttag gcaatagaga
     5881 agtgtttttt gaatattgat aggatttttt aactgtatca tagcagataa caggtattgt
     5941 tttgctattt tttacatctc catcaataaa gtaatgactt ttactatcat ggtaaatctt
     6001 acctaggtaa cttttatctt tagctacttc ccaagaagca aaatgcccag agataatatc
     6061 tttataaaat ctaccagttg taataggaaa tttgttggta aatatctctg gactcgttag
     6121 gtctttccaa agattattag cttcttcatc aatgccagca tggacaaaaa tttgattttc
     6181 tgtttcaaaa taacgactat cttcatatcg tttttggaac cagtttataa atggaatata
     6241 cttatcatta tttctaattt cgtttctaac acctgtttca aagttgttag gatttgtttt
     6301 taaaatatag ttcaattcct ctgtagagaa gaaactcttt attgtttctg gaaacgcaga
     6361 agcagtagga ttatctaaaa tcaaccaatc ataaaaccat tcttcatgat ttccaaaaag
     6421 tgtaataatt tgttttggat aaatcttttc aagttcaatt attttagaaa tgacttgaaa
     6481 agattgagaa ccgtaatcaa tatagtctcc aagtaagata agtttacttt gtttatcaga
     6541 taaatctatt ttattgagag atttaataaa ctcattgtag tgcccatgta tatcagatac
     6601 ggaataataa attgccatat aagattcttt ctataatcaa cgtgaattta cagcgtatat
     6661 gtaatttata taattagcaa aatcacccat acgttttcta tcgttatgaa acttatcgaa
     6721 ccaagaggta tctttgttat tgatttgagc caagcctcta atagatataa ggttatctct
     6781 aattctatta tgaatattag ttcttgtatc atcaagtgta tcttgctctt cttttgtaag
     6841 tattcgccat tttcctctca tttcagcata cttcgcactg tactcgataa gttctttcca
     6901 gtatgcttga aattcagggt cataaatgtt tgatgatttt ataagttcat ctaaaattat
     6961 ttcagcttgt tcaaaagtta cgatttcttt gtcttttaga aaatcgttat aagtaaaaat
     7021 ttgcatagta agctccttta atttttgaaa taattataac acattattta gtaattagaa
     7081 ttacattaga acaagaaaac cataaatttc cattgtattg acctacgttt aaatctttta
     7141 gagtaacagg acaggtttta ttatttgcca tttcttgaac agaagcagta ggggataatg
     7201 tatttacttt gacttgtatc atctccataa agaaatcaga atcctcatct tgaattgaca
     7261 cgttaagtcg taaagctacg ggcttattag tctctctgtc taatacttct gtatagcctt
     7321 ttactgctat aaatttgttg ccaagcagtt ctggctttaa aaaatcattt agcttcatgt
     7381 gtacctcttt tctatcatcg cagagcgatg aggaacagat atttttgctg aaaatctatt
     7441 aaatttaagc aaaaatatct gttgaaatta ttttgacttt gttacgtata attgtagttc
     7501 ttttataaaa tcgaattgag ttgtatcaag ataagggctt tcccagtatt gggcagattc
     7561 tttaccagag ccttgtatat aaagatagcc tgaacctttt tcttcaatag gttttaactt
     7621 atcaggagta gccgaaccaa agaccatgtg atagccttca ctagaattag caccaagagc
     7681 aattctcaat cctaaattat ctctgagttc agtacttaaa gtagtactag catttacttg
     7741 ttgggcagac actaggataa aaatgcctga ctgtcttcca agtagaatga tttgtttaat
     7801 cccatccata acttcagtga taatctctct tgatttttta tctgaacctg tagcttgaaa
     7861 tgctcccatt tcatcaaata taagccatac tggcttaaat ccatggttag taaaatttga
     7921 accatactga aagttatcac gcatgacttg atatcgttcc tgcatttcct caactacgac
     7981 tctcacaatg cgagctatat tatttggggt ggttgctacg tatttatttc caaagtaatg
     8041 agacaagcta cctaggtcag agttcttagg gtcagctata taaactgttg attgacgttt
     8101 tagaaattct aaaatcaaaa cagatataag cacggatttc ccacttccag ttccacccga
     8161 tactaaaata tgtgagcatt tgacaggatt ataatttaca ccatatccta aatctatatc
     8221 aaggctatct atctcttgtc tttggctgtg agattgtaga actaaccttt ttggttttat
     8281 gtaatagaaa tgatattcta taaaactagg tcgaataatc ttttcctcaa gctctagttc
     8341 aagcacgtca gaaagtacat catcaagaga ttgaactttt ttactaaatt catcgcccgt
     8401 tataagagct ttgataagaa catgaccttt ttgtctatct atctcgtatt ctaatactgc
     8461 acttctaacg attttttcat agcctgaacc atctttagat gtggtataaa gtctgtttgt
     8521 gtggagtaca taaagtaagc tctcacgtat aataaggtaa tgctctaagt catatcgaaa
     8581 aatttttatt ttcagatgaa ttttatagat aataaatcca cctaaaaata tgaagagaat
     8641 ttgaacaaaa gttggagccc taatattaac aatagtggaa aatagaatgc aggcagagat
     8701 acttagtatc agccagtgca ttatttttaa cttataacag gaaattatat tgtttcttgt
     8761 taaatcagca ctttgtctta atttaaacat attagttaga taccttttat tttatctaaa
     8821 agctctttta aaagttcgta aaaccctaag agcttgattt ttgcgaaata atatgttgag
     8881 ataagtagtg gaatacaccc aaggataagg atagaattcg aaaagaaatg tccttgaggg
     8941 aatataaaaa ttgctatgcc agctaatatc acaaatccta aaagaaatag atatgctttt
     9001 aaattatcac tcatttcatt acctcctcta ataagcaatt attttaagga aaactataaa
     9061 gatatagtcg ccgataaaat agcgtggtcg gggaaaccga ctttattttg ataatcagga
     9121 ttttctaaga atctccaaga ataacacaca ttagaaatag gaatgtttcc tataatatgg
     9181 tctaatttac aatatttcca agagttctcc tcagacggag tatgtacagt taaacctgct
     9241 ttattcattt ctgattttag taatggatag gagtaaaatt ctctaggttt accttgatag
     9301 gaatgagtat catcattctg cttgaaaaag ccattattaa agtcacctag aataattgtg
     9361 ttttcatgaa ttggtaaatt gaagattagc ttgtctagtt gtgtttttct gtgtttgaaa
     9421 tcttcaaaaa cattttcccc tcctatcttg atacgaactc caataatgtt taattcttgt
     9481 ccttcaattg tcactctaac gtgtaaaaag tttggattat tatcatcatt atcgatagta
     9541 atgacttggc aatcattaac taaatcactc tttattgcaa taagaatttc atttccaaaa
     9601 tctatagtac gcacatcttc aaagattgta taaccattag tttgaaggct agaacagaat
     9661 tgagaatgat tatctgtttt tacatactct gtcagacaga taatatctga attttgctga
     9721 gctagttcct gcgcaatcat ttcaggaatt tgttttcctt ttcttgaacg tagatttata
     9781 ttccaagtgg atgctgtaag ttgtatcata aaatttcctc ctaaaagtta gtccgcagga
     9841 ggaggcacct cctcctgcta tccttcgaat ccatcaaaga tttctcctag ttcgtcttca
     9901 tcatagtagc tttccaattc ctcatagaag taatctaagg cttcttggtc aaaaaagttc
     9961 attgctattc ctcctctcag tatttttttg tacattttaa ttgtacaaaa ttaaaagaag
    10021 aaagtcaaca aaaaagtata ctttaatttc caaaatgtac aaatttaata aaaaaagaat
    10081 gagtctggga caaaaagatt ttgattttag gaattcttta ttataaattt taaaaatcga
    10141 tagattatac aaaaaagcga acaagacaga attctgagta tcagataact cgttttgttc
    10201 gctttttata tttaagatta gacttttgtt ccagactcat tttataaaat tatttttgaa
    10261 attccatatg gtatcagaaa gtaatttgtg gttgactggt gcaacgattt caagaagctg
    10321 tttttctaga atagagaatt tcttgtcaaa atctttttca ggttctgaaa tatcgtgatt
    10381 taattgggtc atcaattctg ctttaagaag aaatttaaca catacaccta aagttacact
    10441 ttgagtattt gtggcactag gcaatatttc tttatatttt ttaattcctt ctgctacttc
    10501 atcggacagt gcaacgttca attttaattc cttttcttcc actggataaa tattttttaa
    10561 agagatagag ttatcttgta caacttttgt ccagtttgtt acagtctttg aattttgaaa
    10621 cgcacgcgtt aaaatggtag ctttagttat attgatacct tctgaagttt catatttctc
    10681 ttttagcatt cttaaatagt aagctgcttc accagatatt cggacttgaa attgtgtcat
    10741 tattagtacc tccgtattgt attataccat ttgtacatta aaaggacaat gtataaacga
    10801 ataatctacc ttctcgttca agcattttta caagtttagt aatcttgttg aagatgcatt
    10861 ccatgtgtta cgtttaaaaa agggaattaa agtaatctag ttcctaaaag gttactaaaa
    10921 ataaaaaaac tatcgttttt gtgatagagg taactttttg aaaaggctat ttgactggct
    10981 ttatatactt atgaaatgtt aagagcccaa ctcaaaatcc agtgtccgca aggacgtgcc
    11041 ggttcgaccc cggccgccgg tatagtatag tgttaggaac gttgttattc ttcgttcctt
    11101 ttttatatta tttttggtat aattatagtt attcaaattt tatttagatt aagaaagtgt
    11161 aggggagtat gtcttgttct atcgatttat taaaacatcg gtatttgaaa aatattaaag
    11221 aaaatcctga attgtttgtc ggaattgagt tggagtatcc tgttgcaagt ttagaagggg
    11281 atgctacaga tgttgaagtt ataaaggatc tatttcatta tttagtttct actttggatc
    11341 tcaccgtagc aaagatagat gattttggca atctgatcca gttagtagat ccgataagtc
    11401 aggatgctat tttatttgaa gtttcctata caacgattga gtttgcattt ggtaaggctg
    11461 aaacgattca agaggtcgaa aatcgtttca ataattatat gaatgtaatt cagagaaagt
    11521 tagctgaatc aaatcatgct attgttggct gtggtatcca tcccaactgg gataaaaatg
    11581 agaattgtcc agtggcttat ccacgctatc agatgttgat ggattatttg aatttgagta
    11641 gaaatattat taaatcagat ttacatcatt tccctgaata tggtactttt atctgtggga
    11701 gccaggttca gctggatatt tcaaaaacca actacttacg ggtgattaat gcttttactc
    11761 aaattgaagc ggctaaggct tatttatttg caaactctga gttttcgggt gcggattggg
    11821 atacgaaaat ttcaagggat attttctggg aagaatctat gcatggtatc tatccagaga
    11881 atgttggggt caatgctaga ctccttaatg atgaagctga tttttttgac tatctaaatc
    11941 attctgcgat ttttactgcg gaacgtgatg ggcagaccta ttatttttat cctattcagg
    12001 ctggggacta tttggctacg cctgaaatcc aagcattttc tctgaatggg gatgaggtta
    12061 ttatttaccc ccaagagaag gattttgaaa ctcatcgtag ttaccagtac caagacttaa
    12121 cgactcgagg aacagttgag tttcgtagtg tgtgtacaca gccacttgat agaacttttg
    12181 cttctgcagc ttttcacttg ggattattgg ttaatttaga caagttagaa gcttacttag
    12241 aaacagcacc tttctttaaa gtatttggtt atgattacaa gtctttaagg agacaatttt
    12301 ctaagaaaaa tcttacagat gaggaagaaa ctacgattat tgaattttcc aaagacttac
    12361 tcctactagc tgaggaggga ctagtggtga gaaataagga agaaatgacc tatttacagc
    12421 ctttgagaga agaattgagc ctataatttc tcttataaag ggagaatttt ctgaaaaatc
    12481 atgatataat ggacgagact atagataaag gatagagagt aatgacatta gtttatcaat
    12541 caacgcgtga tgccaacaat acagtaactg ccagtcaagc aattttgcaa ggtttggcga
    12601 cggacggcgg tttgtttaca ccggttactt atccaaaggt agatttggac tttgacaaat
    12661 tgaaagatgc ttcttaccag gaagttgcta agctagtttt gtcagcattt ttagatgact
    12721 ttacagctga ggagttggac tactgtatca acaatgccta cgatagcaaa tttgatactc
    12781 cagctattgc accattagtg aaattagatg ggcaatacaa tttggaactt ttccatggtt
    12841 caacgattgc ctttaaggat atggccttgt ctattttgcc atactttatg acgactgctg
    12901 ctaagaaaca tggtttggag aacaagattg ttatcttgac agcgacatct ggtgacacgg
    12961 ggaaagctgc tatggcgggg tttgcggatg tgcctggtac tgagattatc gtcttttatc
    13021 caaaggatgg tgtcagcaag attcaagagt tacaaatgac cactcagact ggcgacaata
    13081 ctcatgttat tgctattgat ggtaactttg acgatgcgca aacaaatgtg aagcacatgt
    13141 ttaacgatgt ggctcttcgt gaaaaattga ctaccaacaa gttgcaattt tcatcagcta
    13201 actctatgaa cattggtcgt ctggtgccac aaattgttta ttatgtttat gcttacgctc
    13261 aattggttaa gactggtgaa actgtagctg gtgaaaaggt taacttcaca gtaccaacag
    13321 gaaactttgg aaatatcttg gctgcctttt atgccaaaca aattggtttg ccagttggta
    13381 aattgatctg tgcttcaaat gacaacaatg ttttgacaga cttctttaaa acacgtgtct
    13441 atgacaaaaa acgtgagttt aaggtaacaa ccagcccatc tatggatatc ttggtatctt
    13501 caaacttgga gcgcttgatt ttccatcttt tgggaaataa tgctgaaaag acagctgaac
    13561 tcatgaatgc tttgaacatg caaggacaat ataagttgac agactttgat gcagagattt
    13621 tggacctctt tgcagctgaa tatgcgactg aggaagaaac agcggcagaa atcaagcgtg
    13681 tttatgagtt agattcttat attgaggatc cacatacggc ggttgcctca gcagtttata
    13741 gaaaatacca agcggttact gatgatgcga ctaagacagt gattgcttca acagctagtc
    13801 cctacaagtt cccagtagtt gcagtagaag ctgtaactgg aaaagcaggt ttaacagact
    13861 ttgaagcttt ggctcaatta tatgaaatct caggcgttgc agtgccacca gcagttgatg
    13921 ggcttgagac agctcctgtt cgtcacaaga caacagtggc agctgctgac atgcaagtag
    13981 cggttgaggc ttatttagga ctttaagata gagggagtaa actcggttgg gaaaccaact
    14041 gagtttcttt tcatcaggag gagagattgt ttaagaaaaa taaagacatt cttaatattg
    14101 cattgccagc tatgggtgaa aactttttgc agatgctaat gggaatggtg gacagttatt
    14161 tggttgctca tttaggattg atagctattt caggggtttc ggtagctggt aatattatca
    14221 ccatttatca ggcgattttc atcgctctgg gagctgctat ttccagtgtt atttcaaaaa
    14281 gcatagggca gaaagaccag tcgaagttgg cctatcatgt gactgaggcg ttgaagatta
    14341 ccttactatt aagtttcctt ttaggatttt tgtccatctt cgctgggaaa gagatgatag
    14401 gacttttggg gacggagagg gatgtagctg agagtggtgg actgtatcta tctttggtag
    14461 gcggatcgat tgttctctta ggtttaatga ctagtctggg agccttgatt cgtgcaacgc
    14521 ataatccacg tctgcctctc tatgttagtt ttttatccaa tgccttgaat attctttttt
    14581 caagtctagc tatttttgtt ctggatatgg ggatagctgg tgttgcttgg ggaacaattc
    14641 tgtctcgttt ggttggtctt gtgattttgt ggtcacaatt aaaactgcct tatgggaagc
    14701 caacttttgg tttagataag gaactgttga ccttggcttt accagcagct ggagagcgac
    14761 ttatgatgag ggctggagat gtagtgatca ttgccttggt cgtttctttt gggacggagg
    14821 cagttgctgg gaatgcaatc ggagaagtct tgacccagtt taactatatg cctgcctttg
    14881 gtgtcgctac ggcaacggtc atgctgttgg cccgagcagt tggagaggat gattggaaaa
    14941 gagttgctag tttgagtaaa caaacctttt ggctttctct gttcctcatg ttgcccctgt
    15001 cctttagtat atatgtcttg ggtgtaccat taactcatct ctatacgact gattctctag
    15061 cggtggaggc tagtgttcta gtgacactgt tttcactact tgggacccct atgacgacag
    15121 gaacagtcat ctatacggca gtctggcagg gattaggaaa tgcacgcctc cctttttatg
    15181 cgacaagtat aggcatgtgg tgtatccgca ttgggacagg atatctgatg gggattgtgc
    15241 ttggttgggg cttgcctggt atttgggcag ggtctctctt ggataatggt tttcgctggt
    15301 tatttctacg ctatcgttac cagcgctata tgagcttgaa aggataggaa atgcaaaaaa
    15361 cagcttttat ttgggattta gacgggactt tattggactc ttacgaagcg attttatcag
    15421 ggattgagga gacttttgct cagttttcta ttccttatga taaggagaag gtgagagagt
    15481 ttatcttcaa gtattcggtg caaaatttgc ttgtgcgggt ggcagaagat agaaatctgg
    15541 atgttgaggt gctaaatcag gtgcgtgccc agagtctggc tgagaagaat gctcaggtag
    15601 ttttgatgcc aggtgcgcgt gaggtgctag cttgggcaga cgaatcagga attcagcagt
    15661 ttatatatac tcataagggg aacaacgctt ttaccattct caaggacttg ggggtggaat
    15721 cctattttac agagatttta accagtcaga gtggctttgt gcggaagcca agtccagaag
    15781 cggctaccta tctgctagat aagtatcagc tggatcctga gaagacctat tatatagggg
    15841 accggacttt agatgtggaa tttgccaaga atagcggtat tcaaagcatc aactttttag
    15901 aatcttcttt tgaaggcaat cacaggattc aagcactagc agatatttcc cgtatttttg
    15961 agactaagtg ataaaaagat tgtgtcagtt ttgtgacaga gacctaacaa actatttcaa
    16021 gtaatctagt ttgttacaag gaatagacag ttctgttaaa taggcccgag agggcttttt
    16081 ttctacattt tttgtgttat gatagacagg tactcatttg aaaggaattt gaaagaatga
    16141 agaaaagaat gttattagcg tcaacagtag ccttgtcatt tgccccagta ttggcaactc
    16201 aagcagaaga agttctttgg actgcacgta gtgttgagca aatccaaaac gatttgacta
    16261 aaacggacaa caaaacaagt tataccgtac agtatggtga tactttgagc accattgcag
    16321 aagccttggg tgtagatgtc acagtgcttg cgaatctgaa caaaatcact aatatggact
    16381 tgattttccc agaaactgtt ttgacaacga ctgtcaatga agcagaagaa gtaacagaag
    16441 ttgaaatcca aacacctcaa gcagactcta gtgaagaagt gacaactgcg acagcagatt
    16501 tgacaaccaa tcaagtgacc gttgatgatc aaactgttca agttgcagat ctttctcaac
    16561 caattgcaga agctccaaaa gaagtagcat caaattcaga agttgcagag acagtgactg
    16621 ctgcagaaga agtggcacca tctacgggca cttctgtccc agaggagcaa acggccgaaa
    16681 caactcgccc agttgaagaa gtagctcctc aggcaacgac tctagctgag aagcaggaaa
    16741 cacaagtgag ctctcaaacc gagtcagcag tggaagcaac tacaatgcca gtagaagaaa
    16801 aagcaaccga aacaactgca acaagttcag aagcaaaaga agtagcatca tcaaatggag
    16861 ctacagcagc agtttctact tatcaaccag aagagacgaa aacaatttca acaacttacg
    16921 aggctccagc tgcgcccgat tatgctggac tggcagtagc gaaatctgaa aatgcaggtc
    16981 ttcaaccaca aacagctgcc tttaaagaag aaattgctaa cttgtttggc attacatcct
    17041 ttagtggtta tcgtccagga gacagtggag atcacggaaa aggtttggct atcgacttta
    17101 tggtaccaga aagttcagaa ttaggggata agattgcgga atatgctatt caaaacatgg
    17161 ccagccgtgg cattagttac atcatctgga aacaacgttt ctatgctcca ttcgatagca
    17221 aatatgggcc agctaacact tggaacccaa tgccagaccg tggtagtgtg acagaaaatc
    17281 actatgacca cgttcacgtt tcaatgaatg gataaacccg acttggtaac atcattttga
    17341 cgaatgagat ctagctttcg tgataggaag cgattctcgt tcgttttttc tttgtcatac
    17401 tcttcgaaaa tctcttcaaa caacgtcagt tttatctgaa acctcaaagc tgtgctttga
    17461 gcaacctgcg actagcttcc tagtttgctt tttgattttc attgagtatc aatttgaatg
    17521 gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca ttcttgcaat ctattttata
    17581 gtagattgaa actagaatag tacacaactg cttctaaaac attgttagaa atcgatttga
    17641 ctgtcctgat cgatttgtcc tgctcttatt tcatttcact atactttata ttataattga
    17701 ctggtcaaat attgataaat caataaaaag agaggggaag aaatgctaga gattcaagat
    17761 ttactgtatc aactccgctt gtctgagcaa gtgagtacgc aattgtttga aaaagcttgg
    17821 gattagtttg acacggtatc agattttact gtttttgctg gagcattctc tttgtaacca
    17881 aatggcggtt caggagcgtt tgaaaattga tcaggctgct ttgacacgga atttcaagat
    17941 tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct gaaaatcagc gggaagtatt
    18001 ggtagaggct gcgaagtatg ccaaggagca gttagtggtg aatccccctc tgcaacatat
    18061 caaggttaag gaagagatgg aaagtatctt aacagagttt gagagaacag aactcagccg
    18121 tttattaaat aaattggttt tgggtattga aaatatagaa atttaaggag aaatagatgt
    18181 caattattac aattatttta acaacgatcg ttgcttggga gcatttttac attttttatt
    18241 tagaaagtat tgccacgcaa tcagatgcga ctagtcgtgt atttaatatg gaaagggaag
    18301 aattggctca tccgtcagta agtttattgt tcaaaaatca agggatttat aaggctctgc
    18361 taggagtctg tctcttgtat ggcatttatt tctcacagaa tttagaaatt gtgactattt
    18421 ttgtcttatt tgtgattggt gctgcgactt acggctcttt aacagcggat aaaaaaatta
    18481 ttttgaaaca aggtggatca gctattttgg ccttgattag tattttactc tttaaataca
    18541 cttgaaggtc gattctaatc tcgctaatcc tttttaatcc agaataaggg aaatatgtta
    18601 tacttgtttt taagaaaaaa gtttcattga attggttttg aggagttaga aatgaaagta
    18661 ttagtgacag gttttgagcc cttttgaggc cattaaaggt ttaccagctg aaatccatgg
    18721 tgctgaggtc cgttggctag aggtgccgac agtttttcac aaatctgctc aagtattgga
    18781 agaagagatg aatcgttatc aacctgactt tgtcctttgt attgggcaag ctggtggaag
    18841 aactagtttg acacctgaac gagtggccat taatcaagac gatgcacgta cttctgataa
    18901 cgaagataat caaccgattg accgtcccat tcgcccagat ggtgcttcgg cctactttag
    18961 tagtttgccg attaaagcga tggttcaagc tataaaaaaa gagggcttac cggcctctgt
    19021 ttccaatacg gcagggactt ttgtctgcag ccatttgatg tatcaggctc tctatttggt
    19081 agaaaagaaa tttccatatg ttaaggcagg ttttatgcat attccttata tgatggaaca
    19141 ggtggtgaac agaccgacta ctccagctat gagtttagtg gatattcggc gagggataga
    19201 agcagcaatc ggcgctatga tagaacatgg agatcaggaa ctcaagttgg taggcggaga
    19261 aactcattga tagaaaaaag cttgagggga aaaaccttca agcttttgga cgttttcgag
    19321 ccaatactgc tcggtaaaac ataattttag tgcattggat ataaggtagg agtgaaaaac
    19381 tagcaatgcc aaaggtaatc caattgagga agtaccaagg aagaagctgt aaatctagga
    19441 caaagcgctg gaacttgtag cccttcataa aggaacggct agtttttagg attcgtcttg
    19501 gtgggacctg tcctaggtct agactataac agagaagaaa ttccacctgt gaataggcat
    19561 aatactgtgg aatatagagg atatttccta caatgatcaa gatgagactt gcaagaaagt
    19621 agagtccaaa gaccatgagg aaacgctcgg tttcaactga tgagagatct agatttggaa
    19681 actcaggatg tagggtgacg aattttttgg ctaaaaagct actataaaag aggaggtaaa
    19741 tcccaagtaa attagggata ctccataaaa agagatagaa acgtttgaga agtagggtca
    19801 aaaaggtttg agaaaagcgc tcctcatcaa agagagctag gctgtttttt acagatggct
    19861 ccgttttaga atctttcatg agtgtcagtg ttgcatagac ggaactggtc aaaagaatag
    19921 tcccgataaa ggagactagt agaggaaaga ggtaggtttg aagtatttgg ccaagtatgc
    19981 tgaaaaatgg ctgttctaaa acagtcccgt ggatccgaga taagggatta agaaaactag
    20041 ataagatgac cagcatactg ggaaggatat agaggagaaa gagacggggg gtgtcagcct
    20101 gaaaatgttt tgactcctga cgaattgttt ttaaatcaat ttttggatag ttcattctct
    20161 tattatacca tagttcttat acatagttcg tgacagttcc tacttttttt gataaaatca
    20221 tacagtgtgt ccttgggcac actgtatgaa ctgggactgt ctttcccagc ttcggaggta
    20281 aaaaatgtca gattcaccaa tcaaatatcg tttgattaag aaagaaaaac acacaggagc
    20341 tcgtctagga gaaatcatca ctccccacgg tacctttccg acacctatgt ttatgccagt
    20401 tgggacacaa gccactgtca aaactcagtc acctgaagaa ttgaaggaga tgggttcggg
    20461 aattatccta tcaaacacct atcatctctg gcttcgccct ggagatgaac tcattgcacg
    20521 cgctggtggt ctccacaagt tcatgaattg ggaccagcct atcttgacag atagtggtgg
    20581 ttttcaggtt tattctttag cagatagccg taatatcaca gaagaaggag taacctttaa
    20641 aaatcatcta aatggttcta agatgctcct atccccagaa aaagccatct ctattcagaa
    20701 taatctgggt tcagacatca tgatgtcctt tgatgaatgt cctcagtttt atcaacctta
    20761 tgactacgtt aagaaatcga tcgagcgtac cagccgttgg gctgagcgtg gtttgaaggc
    20821 tcaccgtcgt ccacatgacc aaggtttgtt tggaattgtg caaggtgcag gatttgaaga
    20881 ccttcgccgc caatcagctc atgatcttgt cagcatggat ttctcaggct actctatcgg
    20941 tggtttggca gtgggagaaa cccatgaaga gatgaatgcg gtcttggact ttacaactca
    21001 actgctgcct gaaaataaac ctcgttatct gatgggtgtg ggagcgccag atagcttgat
    21061 cgatggggtc attcgtgggg tggatatgtt tgactgtgtc ttaccgactc gaattgctcg
    21121 taacgggact tgtatgacca gtcaaggacg tttggttgtg aaaaatgccc agtttgctga
    21181 ggactttacg ccactggatc ctgagtgtga ttgctacaca tgtaataact atacacgcgc
    21241 ttaccttcgt cacctgctca aggctgatga aacctttggt atccgcttga ctagctacca
    21301 caatctttac ttcttgctta acctgatgaa gcaagtgcga caagccatca tggatgacaa
    21361 tctcttggaa ttccgtaagt attttgtgga aaaatatggc tataataagt caggacgtaa
    21421 tttctaaaat ggaattgata taagctaaaa atcctaagtt ttctcttagg atttttcttc
    21481 tttttttgat agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat
    21541 ggttttcctt ggttaggatt acaggtttac ttttggtact cttgtatcac ttctttcaga
    21601 cgatctttcc tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga
    21661 ttacagctct actcattgaa gaattttcta aaaaccatga gattgatttg ataggatttt
    21721 ttagaagacg cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc
    21781 cttttacttt cttggttcgc caagactatg ttgctggaat tggtggccag attgcgagcg
    21841 tcttaggctt tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt
    21901 tcattcctca tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc
    21961 tttggggatt ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg
    22021 ggatggtctt tctcttatct gctgttgcct tcttgatcag tttcttctcc atgtttattg
    22081 gtagttttct agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc
    22141 cattcttttt gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg
    22201 tcaagcagtt ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct
    22261 ttggtttcct agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta
    22321 tcggcttctt acttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac
    22381 atgaaaagac acatcatata caggagccga agattatcag ctttttagcg gatactagct
    22441 atgcggttta tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc
    22501 ttcttgctgt attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg
    22561 tattggaacc ttggattgca ggcaagaaca cacctattgt ccaaaccctt cgtcccctgc
    22621 cttatattca cgcaattctt gcagcaggta caggaatctt gaccatcatt gtctgcacgg
    22681 tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga
    22741 agcaagctgc aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca
    22801 gtttgggaat tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata
    22861 cagcactaca gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca
    22921 agaccgcaaa tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg
    22981 tcattgcgac tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga
    23041 aaaatcttcc taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa
    23101 aagagaccta tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga
    23161 caccttacat tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg
    23221 caggaacaga ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat
    23281 tgtatgcaga tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa
    23341 aataacttgt attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca
    23401 aaaaataggt ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa
    23461 taaattgtag aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga
    23521 tcagtttttc tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa
    23581 gtttgggaaa catgtagagc agattcctga aggggctgag gtgattgact atacaggtta
    23641 tagcattgcc ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat
    23701 ggacaacaac attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt
    23761 taccagtttc ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga
    23821 aaatcttgga aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga
    23881 aggtccatat ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc
    23941 gggtgttgag gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc
    24001 ccttgcacca gaacgtgatg gggtggagga ctttgttcgt acagttacgg gcgaaggtgt
    24061 gacggttgct cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc
    24121 tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt
    24181 gggtatggtt ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg
    24241 ccaccacgta gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat
    24301 cgctcttatc acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg
    24361 agaattccca gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc
    24421 aggttctatc ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa
    24481 tccgcatgaa gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga
    24541 tgtctgtggc caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt
    24601 ggaattggta gcaacctacc tagatggcgt aaaacgttat caagcataag agagaaagca
    24661 gaagttagag actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt
    24721 aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa
    24781 tattacaaat aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg
    24841 acttgcttct tttgttgatg tagacaaacc agttattcgc aagccaacag atgctattgt
    24901 gcgtattgta aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc
    24961 tacttgccaa agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg
    25021 ggaaggagtt tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg
    25081 tggtaaatgc tactactgta aaaaaggaat ttatgctcac tgtgaagacg aagggggctg
    25141 gattttcggt cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga
    25201 taatactctt taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga
    25261 cattctgcct actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag
    25321 cgtagccatt attggttcag gtccagttgg attggctgct cttttaacag cccaattcta
    25381 ttcaccagct aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc
    25441 attcggtgcg actcataagg ttaattcttc agaccctgaa aaagccatta aagaaattta
    25501 tgatttgaca gatggtcgtg gtgtggatgt cgctatcgaa gctgttggta ttcctgcaac
    25561 atttgatttc tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca
    25621 tggtaaacca gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac
    25681 tggtttggta tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat
    25741 tgaaccagaa aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctatga
    25801 agtcttcagt aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc
    25861 agaagcctaa gtagtaaaaa tatttttgta cataagtaaa tagaaattca gtcatccatc
    25921 agatggctgg attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc
    25981 ggaattggtt ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat
    26041 gtacggagat tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag
    26101 tagaaaattt gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt
    26161 ggaacaagaa tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc
    26221 ggaagaccaa cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc
    26281 tcttttgcag gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca
    26341 aaccagtcag gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt
    26401 tttggagttg ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag
    26461 tatggttcaa gaaattgcac aagaaatcat tcgttcagct cggaaaaaag ggacgcagga
    26521 tatttatttt gtccctaagt tagacgccta tgagcttcat atgagggtag gagacgagcg
    26581 ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt
    26641 tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc
    26701 ctatgaccag aagatggcgt ctctacgttt atctactgta ggcgattatc ggggacatga
    26761 gagtttggtt atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga
    26821 tattgaagaa ttaggcaagc agtacaggca acggggactc tatctttttg ctggcccggt
    26881 tgggagtggt aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca
    26941 agttatgtcc atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt
    27001 gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc
    27061 agatctcttg attatcggag aaattcgtga catcgagacg gcgcgtgcag tggtcagagc
    27121 tagtttgaca ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta
    27181 tgagcgtctg ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt
    27241 ctgctaccag agattaatcg ggggaggagg aatcgttgac tttgcaaaca gagattatca
    27301 agaacaccaa gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat
    27361 cacaagtctt caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca
    27421 ccctatttaa caatctcttt tctagcggtt ttcatctggt ggagactatc tcctttttag
    27481 ataggagttc cttgttggac aagcagtgtg tgacccagat gcgtacaggc ttgtctcagg
    27541 ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt
    27601 tatctctagc tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc
    27661 tagacaatct ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt
    27721 tgctgggttt tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg
    27781 atagtagcaa tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg
    27841 tagggcttgt ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga
    27901 tgagtgtctt ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact
    27961 tgacagccta ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc
    28021 agatttttca aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc
    28081 tggctcaaac cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct
    28141 ttaggaagga attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg
    28201 agttggaaat ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgtacca
    28261 tgaatttggt gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg
    28321 cggcaatgct catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg
    28381 atgacattct tgaaaaaagc taaggttaaa gcttttacat tgattgagat gttggtggtc
    28441 ttgctgatta tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa
    28501 gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt
    28561 tatagcttag aaaagaatga agatgctagc ctaagaaagt tacaagcaga tgggcgcatc
    28621 acggaagaac aggttaaagc ttataatgaa tactatacta aaaatggagg ggcaaatcgt
    28681 aaagtcaatg attaaggcct ttaccatgct ggaaagtctc ttggttttgg gacttgtgag
    28741 tatccttgcc ttgggcttat ccggctctgt ccagtccact tttgcagcag tagaggagca
    28801 gattttcttt atggagtttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag
    28861 tcagcaaaag actagtctaa atttagatgg gcagacgctt agcaatggca gtcaaaagtt
    28921 gacagttcct aaaggaattc aggcaccatc aggccaaagt attacatttg accgagctgg
    28981 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    29041 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    29101 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    29161 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    29221 gggtagctaa gatggccttg cagacaggtc aaaatcaggt aaacataaac ggagttgaga
    29281 ttcaggtgtt ttctagcgaa aagggattgg aggtctacca tggttcagaa cagttgttgg
    29341 caatcaaaga gccataaggt caaggctttt accttgttag aatccctgct tgccctgatt
    29401 gtcatcagtg ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    29461 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggca
    29521 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    29581 ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt
    29641 ggacgggggt atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat
    29701 caactggttc attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    29761 gtggaaaaag aagaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat
    29821 ctttagtctt ttgttgcaat tttatttgaa ccgacaaatc gcccactatc aagactatgc
    29881 tttaaataaa gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga
    29941 gcaagaaagt ggggaacagg tttttaatct aggtcaggta agctatcaaa acaagaaaac
    30001 aagcttggtg acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt
    30061 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa
    30121 agcggagaaa aaaaatcaga agagaagcct gaaaagaaag agaattccta gtcaattcaa
    30181 ctataatgcg ttgaatccag aatagtccac tgtagtttct agaaaattgc tggaaatgga
    30241 tgttaagctc caattcattt gtttatatct tatttcagtt tactatactt tgtgctaaat
    30301 taaagatatg aaacatgatt ttaaccacaa agcagaaact ttcgattccc ctaaaaatat
    30361 cttcctcgca aacttggtat gtcaagcagc cgagaaacag attgatcttc tatcagacaa
    30421 agaaatttta gatttcggtg gtgacacggg tctattagcc ttgcccctag cccctagcca
    30481 agcaggctaa gtcagtcact cttgtagaca tttctgagaa aatgttggag taagctcgtt
    30541 tgaaagcgga gcagcaagca atcaagaata tccagttttt ggagcaagat ttaccgaaaa
    30601 atcccttgga gaaagagttt gattgccttg ctgttagtcg gcttcttcat catatgcctg
    30661 atttggatgc ggatctctca ctgtttcatc aacatttgaa ggaagatagg aaactcatca
    30721 ttgctgattt taccaagaca gaagctaatc atcatggatt tgatttagct gaactggaaa
    30781 acaagctaat tgagcatggt ttttcatctg tgcatagtca gattctctat agcgctgaag
    30841 acctgtttca agggaatcac tcagaattct ttttaacagt atcccaaaaa tcactcgcct
    30901 agtcagggag tgatttttct ataaggatgg aaaaaagaag ggaaatttga taagatagga
    30961 atatggattt tgaaaaaatt gaacaagctt atatctattt actagagaat gtccaagtca
    31021 tccaaagtga tttggcgacc aacttttatg acgccttggt ggagcaaaat agcatctatc
    31081 tggatggtga aactgagcta aaccaggtca aagacaacaa tcaggccctt aagcgtttag
    31141 cactacgcaa agaagaatgg ctcaagacct accagtttct cttgatgaag gctgggcaaa
    31201 cagaaccctt gcaggccaat caccagttta cgccagatgc tattgcctta cttttggtat
    31261 ttattgtgga agagttgttt acagaggagg aaattactat cctcgaaatg ggttctggga
    31321 tgggaattct aggcgctact ttcttgacct cgcttgataa aaaggtggat tacttgggaa
    31381 tggaagtgga tgatttgctg attgatctgg cagctagcat ggcagatgta attggtttgc
    31441 aggctggctt tgtccaagga gatgccgttc gcccacaaat gctcaaagaa agcgatgtgg
    31501 tcatcagtga cttgcctgtc ggctattatc ctgatgatgc cgttgcgtcg cgtcatcaag
    31561 ttgcttctag ccaagaacat acttacgccc atcacttgct catggaacaa gggtttaagt
    31621 accttaagtc agatggatat gctatttttc tagctccgag tgatttgttg accagtcctc
    31681 aaagtgattt gttgaaagtc tggttgaaag aggaggcaag tctggttgct atgattagtt
    31741 tacctgaaaa tctctttgct aatgctaaac aatctaagac tatttttatc ctacagaaga
    31801 aaagtgaaat agcagtggag ccttttgttt atccacttgc tagcttgcaa gatgcaagtg
    31861 ttttaatgaa atttaaagaa aattttcaaa aatggactca aggtactgaa atataaaata
    31921 gattttgtta taatagttga aaacgcttaa aaaggggtat catgttatga caaaaacaat
    31981 tgcaatcaat gcaggaagtt caagtttgaa atggcaatta tacttaatgc cagaggaaaa
    32041 agtgttagcc aaaggtttga ttgaacgtat cggtttgaaa gattcaattt caactgtaaa
    32101 atttgacggc cgttctgaac aacaaatttt ggatattgaa aatcatacac aagccgttaa
    32161 aattttattg gatgacttga ttcgtttcga tattatcaag gcttatgacg agattacagg
    32221 tgttggacat cgtgttgttg ctggtggaga atatttcaaa gaatcaacag ttgttgaggg
    32281 agatgtttta gaaaaagttg aagagttgag tttgttggct cctctacaca acccggccaa
    32341 tgcagcaggt gttcgtgcct tcaaggaatt gttgccagac attaccagtg tagttgtttt
    32401 tgatacttcc ttccacacaa gtatgccaga gaaagcttat cgctaccctc taccaacaaa
    32461 atattacaca gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc accagtttgt
    32521 agcaggagaa gctgcaaaac tcttgggacg tccattagaa gacttgaagt taattacctg
    32581 tcatattggt aacggaggct caattacagc tgtgaaagcc ggcaaatctg tagacacttc
    32641 tatggggttc actcctcttg gtggtattat gatgggaacg cgtacagggg atattgatcc
    32701 agctatcatt ccttatttaa tgcaatatac agaggatttt aacacaccag aagatatcag
    32761 tcgtgttctt aaccgtgaat caggtctttt gggagtttct gctaattcta gcgatatgcg
    32821 cgatatagaa gcagctgtag cagaagggaa tcacgaggct agcttggctt atgaaatgta
    32881 tgttgaccgt atccaaaaac atatcggtca gtaccttgca gtgctaaatg gagcagatgt
    32941 cattgttttc acagcaggtg tcggtgaaaa tgcagagagt ttccgtcgtg atgtaatctc
    33001 agggatttcg tggtttggtt gtgatgttga tgatgaaaag aatgtctttg gcgttacagg
    33061 agacatctca acagaggcag ctaaaatccg tgtcttggtt attccaacag atgaagaatt
    33121 agtcattgcc cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa aatattcaat
    33181 acaaggagtt gggaaagtta tttttccagc ttctttttct gatgaaattg tccaaaacct
    33241 tgctatgatt ggcttttttg aaaaatatgg tataatagta gtaatttaat agatggagtt
    33301 gagttttgaa gaaaaacttt cgtgtaaaaa gagagaaaga ttttaaggcg attttcaagg
    33361 aggggacaag ttttgctaat cgcaaatttg tggtctacca attagaaaac cagaaaaacc
    33421 attttcgagt aggtctatca gttagcaaaa aactggggaa tgccgtcact agaaatcaaa
    33481 ttaagcgacg gattcggcat attatccaga atgcaaaagg gagtctggta gaagatgtcg
    33541 actttgttgt cattgctcga aaaggagtcg aaaccttggg atacgcagag atggagaaaa
    33601 atctactcca tgtattaaaa ttatcaaaga tttaccggga aggaaatggg agtgaaaaag
    33661 aaactaaagt tgactagttt gctaggactg tctctgttaa tcatgacagc ctgtgcgact
    33721 aatggggtaa ctagcgatat tacagccgaa tcggctgatt tttggagtaa attggtttac
    33781 ttctttgcgg aaatcattcg ctttttatcg tttgatatta gtatcggagt ggggattatt
    33841 ctctttacgg tcttgattcg tacagtcctc ttgccagtct ttcaggtgca aatggtggct
    33901 tctaggaaaa tgcaggaagc tcagccacgc attaaggcgc ttcgagaaca atatccaggt
    33961 cgagatatgg aaagcagaac caaactagag caggaaatgc gtaaagtatt taaagaaatg
    34021 ggtgtcagac agtcagactc tctttggccg attttgattc agatgccggt tattttggcc
    34081 ctgttccaag ccctatcaag agttgacttt ttaaagacag gtcatttctt atggattaac
    34141 cttggtagtg tggatacaac ccttgttctt ccgattttag cagcagtatt caccttttta
    34201 agtacttggt tgtccaacaa agctttgtct gagcgaaatg gcgctacgac tgcgatgatg
    34261 tatgggattc cagtcttgat ttttatcttt gcagtttatg cgccaggtgg agtcgcccta
    34321 tactggacag tgtctaatgc ttatcaagtc ttgcaaacct atttcttgaa taatccattc
    34381 aagattatcg cagagcgcga ggccgtagta caggcacaaa aagatttgga aaatagaaaa
    34441 agaaaagcca agaaaaaggc tcagaaaacg aaataaataa ggaggaatct ggtaatggta
    34501 gtatttacag gttcaactgt tgaagaagca atccagaaag gattgaaaga attagatatt
    34561 ccaagaatga aggctcatat caaagtcatt tctagggaga aaaaaggctt tcttggtcta
    34621 tttggtaaaa aaccagccca agtggatatt gaagcgatta gtgaaacgac tgttgtcaaa
    34681 gcaaatcaac aggtagtaaa aggcgttccg aaaaaaatca atgatttgaa cgagcctgtg
    34741 aagacggtta gtgaagaaac cgttgacctt ggtcatgtag ttgatgctat taaaaaaata
    34801 gaggaagaag gtcaaggtat ttctgatgaa gtcaaggctg aaatcttaaa acatgaaaga
    34861 catgccagca ctatcttaga agaaactggt cacattgaga ttttaaatga acttcaaatc
    34921 gaggaagcga tgagggaaga agcaggcgct gatgaccttg aaactgagca agaccaagct
    34981 gaaagtcaag aactagaaga cttgggcttg aaagttgaaa cgaactttga tattgaacaa
    35041 gtagctacgg aagtaatggc ttatgttcaa acgattattg atgacatgga tgttgaggct
    35101 acactttcaa atgattataa ccgtcgtagc atcaatttgc aaattgatac taacgaacca
    35161 ggtcgtatta tcggctacca tggtaaagtc ttgaaggcct tgcaactgtt ggctcaaaat
    35221 tatctttaca actgctattc aagaaccttc tatatcacta ttaatgtcaa tgattatgtt
    35281 gaacaccgtg cagaagtctt gcagacctat gcgcaaaaat tggcgattcg tgttttagaa
    35341 gaaggacgta gtcatcaaac agatccaatg tcgaatagtg aacgcaagat tatccaccgt
    35401 attatttcac gtatggatgg cgtgaccagt tactctgaag gtgatgagcc aaatcgctat
    35461 gtcgttgtag atacagaata agtaaaatca gggttgacct gattttttgc tagctagagg
    35521 aggttaaact gatgttgaat aagataagag actatttaga ctttgctggt ttgcagtacc
    35581 gtaatcctga taaagcggga gcagagcgag agaagatgct ggcattccgc cacaaaggac
    35641 aagaggcccg aaaggctttt acagaactgg ccaaagcctt tcaagcaagc catccagaat
    35701 ggcaactcca acagactagt cagtggatga atcaggccca gcgtttgaga ccacattttt
    35761 gggtttatct acagagagac ggacaagtga cagaacctat gatggcctta cgtttgtatg
    35821 ggacatctac tgactttgga atttctttgg aagtcagttt catcgaacgt aagaaggatg
    35881 agcaaacact gggcaagcag gccaaagttt tagacattcc aaccgttaaa gggatttatt
    35941 atctaaccta ctctaatggt caaagtcaac ggtgggaggc gaatgaagaa aagcgtcgta
    36001 ctttacgcga gaaggtgaga agtcaagaag ttcgaaaagt tttagtgaag gtagatgttc
    36061 ctatgacaga aaattcgtct gaagaagaaa tcgtagaagg cttattgaag tcttattcta
    36121 aaattcttcc ctattatcta gctacgagaa aataagataa tttgtaaaac atcataaatc
    36181 atacagtcca agagtgaaca gtccgctgtg taattcttgg tctttttgtt tgcgctttcg
    36241 cattatataa taaacttaca aaaacaattc aaaaggagaa caattatgga agtcgtttca
    36301 agtgttctaa attggttttc tagcaatatt ttgcagaatc ccgcattttt cgtaggttta
    36361 ttggtgttga taggatatgc acttttgaaa aaacctgccc atgacgtttt ttcagggttt
    36421 gttaaagcaa cagtagggta tatgttgctt aacgtgggtg ctggtggttt ggttacaacc
    36481 tttcgtccaa tcttagcagc tcttaactac aaattccaaa ttggtgcagc ggttatcgac
    36541 ccttactttg gacttgctgc agcaaacaac aaaattgcag cagagtttcc agattttgtt
    36601 ggaactgcaa ctacagctct attgattggt tttggaataa atatcttgct cgtagctctt
    36661 cgaaagatta cgaaggtaag aaccctcttt attactggtc acatcatggt acaacaagct
    36721 gcaacagtat ctcttatggt tctattctta gtaccacaat tgcgcaatgc ttacggtaca
    36781 gcagcgattg gtatcatctg tggactttac tgggcagtta gttcaaatat gactgttgag
    36841 gcaactcaac gcttgactgg tggtggcgga tttgcgattg gtcaccaaca gcaatttgca
    36901 atctggtttg tagataaagt agcaggacgc tttggtaaga aagaagaaag tttagacaat
    36961 cttaaattac ctaagttcct ctcaatcttc cacgatacag ttgttgcatc tgctaccttg
    37021 atgctcgtat tcttcggagc cattctttta atcttgggtc cagacattat gtctaataaa
    37081 gaagtcatca cttcaggaac tctattcaat cctgctaaac aagatttctt tatgtacatt
    37141 atccaaacag cctttacctt ctcagtttac ttgttcgttt tgatgcaagg tgtccgaatg
    37201 ttcgtatctg agttgacaaa cgccttccaa ggtatttcaa acaaattgtt gccaggttca
    37261 ttcccagcgg ttgacgttgc agcttcttat ggatttggtt ctccaaatgc tgtcttgtca
    37321 ggatttacct ttggtttgat tggtcaattg attacaattg tcttgctcat cgtctttaaa
    37381 aatccgattc ttattattac aggatttgta ccagtgttct ttgacaatgc agccattgcg
    37441 gtctacgctg ataaacgcgg cggatggaaa gcggctgtta tcctttcctt tatatcaggt
    37501 gtccttcaag ttgctctagg agctctttgt gtggcccttc tcgatttggc atcttatggt
    37561 ggctaccatg gaaatatcga ctttgaattc ccatggcttg gatttggata tatcttcaaa
    37621 taccttggta ttgttggtta tgtacttgtg tgtctcttct tgcttgttat tcctcaactt
    37681 caatttgcca aagcaaaaga taaagagaaa tattacaacg gtgaagttca agaagaagct
    37741 tagtatctag aaaaggagaa ataaaatggt taaagtatta gcagcgtgcg gaaatggaat
    37801 gggttcatca atggttatca agatgaaggt tgaaaatgct ctccgtaagc ttaatcaaac
    37861 agattttaca gtcaattcat gcagtgtcgg tgaagctaaa ggtttagcag taggatatga
    37921 catcgtaatc gcttctcttc atttgattca agaattggaa gggcgaacta atgggaagtt
    37981 aattgggctt gataacttga tggatgataa agaaatcacc gaaaaactca gtcaagcact
    38041 acagtaaaag gttggagggg gctggacaga aactgagagt tatcgtttct gtccttctcc
    38101 ctctttaaat aaaggaggca gatatgaatt taaaacaagc tttaattgac aatgactcga
    38161 tccgactagg tttagaggct aacaattgga aagaagcagt caaggtagca gtagatccct
    38221 taattgaaag tggggcaatt ttgccagagt attacgatgc tatcattgaa tcgactgaag
    38281 agtatgggcc ttactatatc ttgatgccag gtatggctat gccccacgct agacctgaag
    38341 ctggtgtgca aagtgatgcc ttttcattga ttaccttaca aaatcctgtt gtattttcag
    38401 atgggaaaga ggtatctgtt ttgttggcac tagcagcaac aagttcaaaa attcacacaa
    38461 gtgtagccat tccacaaatt attgccctgt ttgaattaga agattctatt gcacgtttac
    38521 aggcttgcca gactaaagaa gatgtcttgg ctatgattga agaatctaag gatagccctt
    38581 atctcgaagg attggatttg gaaagttaga aagaggaata aagaaatgac aaaaagaata
    38641 cctaatttac aagttgcatt agaccattca gacttgcaag gagcgattaa agcagctgtt
    38701 tctgttggtc aggaagtaga tattatcgaa gctggaactg tttgcttgct tcaagttgga
    38761 agtgaactgg ctgaagtctt gcgtagcctt ttcccagata agattattgt ggcagacaca
    38821 aaatgtgctg atgctggtgg aacagttgct aaaaataatg cggttcgtgg agcagactgg
    38881 atgacttgta tctgttgtgc aaccatccct actatggaag cagctctaaa ggctatcaag
    38941 actgaacgag gagaacgagg cgaaatccag atcgagcttt atggcgattg gacttttgaa
    39001 caagctcagc tttggctaga tgcaggtatc tcacaagcta tttatcacca atctcgtgat
    39061 gctcttcttg ctggtgaaac ttggggtgaa aaagacctta ataaggttaa aaaactcatt
    39121 gatatgggct tccgtgtatc tgtaacaggt ggtctagatg tagatactct caaactcttt
    39181 gaaggtgttg atatctttac ctttatcgca ggtcgtggaa ttacagaggc tgcggatcca
    39241 gcaggagcag cgcgtgcctt caaggatgaa atcaaacgaa tttgggggta aatcatggta
    39301 cgtccaattg gaatttatga aaaggcaacc ccaacacact ttacttggct agaacgttta
    39361 aattttgcca aggagttagg ctttgatttt atcgagatgt ctattgacga acgtgacgag
    39421 cgtttagcaa gacttgactg gagtaaggaa gaacgcttgg aagttgtcaa agaaatctat
    39481 gaaactggtg ttcgtattcc ttctatctgt ttttcaggcc atcgtcgcta cccattggga
    39541 tcaaaagatt cagttctaga ggaaaaatct ctagaactca tgaaaaaatg tatcgaatta
    39601 gctcaagact tgggagttcg tacgattcaa ttagctggtt acgatgttta ctatgaggaa
    39661 aagtcacccc agacacgcca acgttttatc aaaaatttga gaaaagcctg tgactgggct
    39721 gaagaagctc aggtggtact tgctattgaa attatggatg atcctttcat cagtagcatc
    39781 gaaaaatatt tggctataga aaaagagatt gactctccct tcctctttgt atatccagat
    39841 attggtaatg tgtctgcatg gcataatgat atctatagtg agttttatct tggtcatcat
    39901 gccatcgcag ctctccatct caaggatact tatgcagtga cagaaagttc aaagggccag
    39961 ttccgagatg tacctttcgg gcaaggttgt gtcaaatggg aagaagcttt cgatatttta
    40021 aaggaaacca attataatgg acctttccta atcgaaatgt ggtctgaaaa ttgtgaaaca
    40081 gtagaagaaa cacgcgcagc cattcaagag gcgcaagctt ttctctatcc actcattaag
    40141 aaagcaggtt tgatgtaaga tgaatcaagt aatcaatgct atgcgtaaac gagtctgtga
    40201 tgccaatcaa tcattgccaa aacatggact tgtcaaattt acctggggga atgtatctga
    40261 agtcaatcgc gaactcggtg tcattgttat caaaccatca ggcgtggatt atgacgaatt
    40321 gacacctgaa aacatggtag tgactgatct agatggtaag atcctagaag gggatttaag
    40381 accatcttcc gacctcccaa ctcatgtgca attatataag gcttggtcag aaattggtag
    40441 tgtggttcac acccattcga cagaagctgt tgcttgggct caggcaggtc gtgatattcc
    40501 tttctacgga acaacccatg cagattattt ctacggttca attccttgcg cccgtagttt
    40561 gaccaaggac gaagtagaag tggcctatga aaaagatact ggcctggtta tcgtagaaga
    40621 gtttgaacat cgcggactta acccggttga agtaccagga attgttgtac gcaatcacgg
    40681 tccattcacc tggggcaaaa atccagagaa tgctgtttat cactctgtcg tactagagga
    40741 agtatcaaag atgaatcgct ttacagaaca aatcaatcca agagttggac ctgctcccca
    40801 gtacatacta gaaaaacact accaacgtaa acatggacca aatgcttatt atggtcaaaa
    40861 gtaagaacga tgaaggagga gaaaaagata aatttagctc ctctttttac atttgatttt
    40921 tattgagagt aaagttggag ttgaagtaat tttaaaagat tttttagaaa tagcgcttga
    40981 tatatatatg gtaaaataaa aagaattgct gtgatatcaa tagatttggg ggatttttta
    41041 atatggtact ggataaggca agttgtgatt tgcttcaata tttgatggat caagaaacgt
    41101 ccaaaacgat tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa atttattatc
    41161 acattgacaa aatcaatgct gctctgggtg acgaggcgct tcacatcatt agtattccac
    41221 gaattggtat tcacttaacg gaagagcaga gagatgcttg ttgtaaacta ttatcggaag
    41281 tagattcgta cgattatatc atgagtgcgc atgaacgtat gatgataatg ttactatgga
    41341 taggtatttc taaagaacgt attacgattg aaaaattgat agagttaaca gaggtatcta
    41401 ggaatactgt tctcaatgat ttgaatagta ttcgttatca actaactttg gaacaatatc
    41461 aggtgatctt gcaagtgagc aagtcacagg gataccacct tcatgcccac cctcttaata
    41521 aaattcagta tcttcaatcg cttctatatc atatttttat ggaagaaaat gccacttttg
    41581 tatctatttt agaagataag atgaaagaga ggttagatga tgagtgtttg ctttctgttg
    41641 aaatgaacca attttttaag gaacaggttc ctttagttga acaagattta gggaagaaaa
    41701 taaatcatca tgaaataact tttatgttgc aggttctacc ttatttgctg ttaagctgtc
    41761 ataatgttga acagtatcaa gaaagacatc aggatataga gaaagaattt tctttgataa
    41821 gaaaaagaat agagtatcag gtgtctaaga aattaggaga acggttgttt caaaagtttg
    41881 aaatttcttt gtcaggactt gaagtttctc ttgtagctgt tctcctcctc tcctatcgta
    41941 aagatttgga tattcatgca gaaagtgatg attttcggca attaaaactt gctttagaag
    42001 aatttatctg gtattttgaa tcacaaatcc gaatggagat tgagaacaag gatgatttgt
    42061 tacgaaattt gatgatccac tgtaaagcct tgttatttag aaagacttac ggtatttttt
    42121 ctaaaaatcc tctaacaaaa caaattcgat ccaagtatgg agaattattt ttagtcacta
    42181 gaaaatctgc ggaaatttta gaaggagcat ggtttattcg gctaacagac gatgatattg
    42241 cctatttgac gattcatatt ggaggatttt taaagtatac accatcgtct caaaaaaata
    42301 tgaaaaaagt ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt ttgctgaaac
    42361 aatgcaaact ttattttcca aatgagcaaa ttgacactgt atttacaaca gaacaattta
    42421 agagtgtgga agatattgca caagttgatg tagtgattac tactaatgat gatttggata
    42481 gcagatttcc gattttaagg gttaatccta tccttgaagc agaagatatt ttgaaaatgc
    42541 tagactatct taaacacaat atatttcgta ataagagcaa aagtttcagt gaaaatcttt
    42601 ctagtcttat ttcgtcttat attgtagaca gcaagttggc tagtaagttc caagaagagg
    42661 ttcaaacact tataaatcaa gaaatagtag ttcaagcttt tttggaagat atttgaagga
    42721 cagtccaatg atgaacacaa acctgtgttt ttcttggtct tttttagtgt tttgaagggt
    42781 ggtatactaa tctcaaagat aacaattata tccaaaggag gcaacatatg ccaaacgtca
    42841 aagaaattac aagagagtca tggattttag ccactttccc agagtgggga acatggttga
    42901 acgaagaaat cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg tggctaggca
    42961 actgtggtac ttggattaag acaccagctg gtgctaacgt tgtcatggac ctttggtcaa
    43021 accgtggaaa atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa atggcaaata
    43081 tggcaggtgt tcgtaaattg caaccaaact tgcgtgttca gccaatggtt atcgatccat
    43141 ttgctatcaa cgaactagac tattacttag tttcacactt ccacagtgat catatcgacc
    43201 catacacagc tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag tttatcggtc
    43261 cttaccactg tggacgaatc tgggaaggat ggggggttcc aaaagaacgt atcatcgttg
    43321 ttaaaccagg tgacactatc gaattaaaag atatgaagat tcatgcagta gaatcatttg
    43381 accgtacttg cttggtaact ctcccagtga acggtgctga tgagacaggc ggtgaacttg
    43441 ctggcttggc tgttacagat gaagaaatgg ctcaaaaggc tgttaactat atctttgaaa
    43501 caccaggtgg aaccatctat catggtgcag attctcactt ctcaaactat tttgcaaaac
    43561 atggtaaaga ctttaaaatt gatgttgctt tgaataacta tggtgaaaat ccggtaggta
    43621 tccaagacaa aatgacatct atcgaccttc ttcgtatggc agaaaatctg cgtaccaaag
    43681 tcattatccc agttcactat gatatctggt ctaacttcat ggcttctact aatgagattc
    43741 tagaactttg gaaaatgcga aaagatcgct tgcaatacga tttccatcca tttatctggg
    43801 aagttggcgg taagtacact tatcctcaag atcaacactt agtagaatac catcatccac
    43861 gtggttttga tgattgtttt gaacaagact ctaacattca atttaaagct ttgctataat
    43921 ataaaaatat tctttggagg ttatccgtat gttgcatgat acggataatt ttcatataat
    43981 agtaaaatag aatgtgtgat tcaataatca cctcaaatag aaaggaaatt ctatgtcaaa
    44041 tctatctgtt aatgcaattc gttttctagg tattgacgcc attaataaag ccaactcagg
    44101 tcatccaggt gtggttatgg gagcggctcc gatggcttac agcctcttta caaaacaact
    44161 tcatatcaat ccagctcaac caaactggat taaccgcgac cgctttattc tttcagcagg
    44221 tcatggttca atgctccttt atgctcttct tcacctttct ggttttgaag atgtcagcat
    44281 ggatgagatt aagagtttcc gtcaatgggg ttcaaaaaca ccaggtcacc cagaatttgg
    44341 tcatacggca gggattgatg ctacgacagg tcctctaggg caagggattt caactgctac
    44401 tggttttgcc caagcagaac gtttcttggc agccaaatat aaccgtgaag gctacaatat
    44461 ctttgaccac tatacttacg ttatctgtgg agacggagac ttgatggaag gtgtctcaag
    44521 cgaggcagct tcatacgcag gtttgcaaaa acttgataag ttggttgttc tttatgattc
    44581 aaatgatatc aacttggatg gtgagacaaa ggattccttt acagaaagtg ttcgtgaccg
    44641 ttacaatgcc tacggttggc atactgcctt ggttgaaaat ggaacagact tggaagccat
    44701 ccatgctgct atcgaaacag caaaagcttc aggcaagcca tctttgattg aagtgaagac
    44761 ggttattgga tacggttctc caaacaaaca aggaactaat gctgtacacg gcgcccctct
    44821 tggagcagat gaaactgcat caactcgtca agccctcggt tgggactacg aaccatttga
    44881 aattccagaa caagtatatg ctgatttcaa agaacatgtt gcagaccgtg gcgcatcagc
    44941 ttatcaagct tggactaaat tagttgcaga ttataaagaa gctcatccag aactggctgc
    45001 agaagtagaa gccatcatcg acggacgtga tccagtcgaa gtgactccag cagacttccc
    45061 agctttagaa aatggttttt ctcaagcaac tcgtaattca agtcaagatg ccttgaatgt
    45121 tgtggcagct aaattaccaa ccttcctagg tggatcagct gaccttgctc actcaaacat
    45181 gacttatatc aagacggatg gacttcaaga cgataccaat cgcttgaatc gtaacattca
    45241 gtttggtgtt cgtgaatttg caatgggaac aatcttgaac gggatggccc ttcatggtgg
    45301 acttcgtgta tacggtggaa ctttcttcgt cttctctgac tatgtgaagg cagctgtccg
    45361 cttgtcagcc ttacaaggac ttcctgtgac ttatgtcttt acccatgatt caatcgcagt
    45421 tggggaagat ggtccgactc acgaaccggt tgagcattta gcaggtcttc gtgctatgcc
    45481 aaatctaaat gttttccgtc cagcagatgc gcgtgaaacg caagcagctt ggtaccttgc
    45541 agtgacaagt gagaaaacac caactgccct tgtcttgaca cgtcaaaact tgactgttga
    45601 agatggaaca gacttcgaca aggttgctaa aggtgcttat gttgtatatg aaaatgcagc
    45661 cgactttgat accatcttga ttgcgacagg ttcagaggtt aatcttgctg tctcagctgc
    45721 taaagaattg gctagtcaag gcgaaaaaat ccgcgtagtc agcatgccat ctacagatgt
    45781 ctttgataaa caagatgcag cttacaagga agagattctt ccaaatgcag tccgccgtcg
    45841 tgttgcagtc gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc tcgatggtgc
    45901 cgttctaggt attaatacct tcggagcctc tgccccagca ccaaaagtat tggcagaata
    45961 tggctttact gtagaaaatc ttgtaaaaat tgttcgaaac ttgaaataat cctaaaaatc
    46021 agggcgtaag ctctggtttt tcttaccaga aaagtaaggt acaatcttgt aaaagtagct
    46081 gaaatttgat atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa tccaaatatt
    46141 acttttttaa tcatgcttgt aggtatgatg gccttgatgt tctttatgca acgttctcaa
    46201 aagaaacaag ctcaaaagcg tatggaaagc ttaaataaac tacaaaaagg ctatgaagtg
    46261 attacaatcg gtggacttta tggaacagtc gatgaagtag atacggagaa gggaacaata
    46321 gttcttgacg tagatggagt ttacttgact tttgaactag ctgctatcaa gacagtatta
    46381 ccgctgaaag aaacagcttc actagaaggc gcaattgaaa aataagacgg gatcacgaac
    46441 tcccgttttt ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg tctgtctggg
    46501 aaatatttgc cgtagcccta tggccgagtt tgttatgaaa tcaatgacag ataactacga
    46561 aatccaaagt cgagcaactt cctcttggga acatggcaat ccgattcata aggggactca
    46621 gggaattttt caagagtatg agattcctta tgacaagaac aagacatcgc ttcagattag
    46681 taaggaagat tttgaagcct ttgattatat tatcggaatg gacgcttcaa atatttctga
    46741 cttacgtcag atgtgtccag tagactgtca agataagatt tactcatttt catctgaaag
    46801 tgttccagac ccttggtata caggagattt tgaagaaacc tatcgacgtg ttcaagaggg
    46861 ctgtcaagct tggttagaac gtttagaaaa ggagagttaa ggtggaaaat cttacgaatt
    46921 tttacgaaaa gtatcgtgtc tatctgactc gtccacgatt agagcttttg gcagtagtta
    46981 ccattgtttt ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa ggtgtcttaa
    47041 aactcgataa tggaacgatt gtttatgatg gcagtcttgt ccgtggtaaa atgaatggtc
    47101 aaggtaccat taccttccaa aatggagacc aatatacagg tggcttcaac aatggagcct
    47161 tcaacggaaa aggtaccttt caatctaaag aaggctggac ctacgaaggt gattttgtaa
    47221 atggtcaggc tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt tatgaaggaa
    47281 cttttaaaca aggcgttttt caacaaaaat aaagcctcct tatcaaagga ggtattatta
    47341 gaatcgcaag gtaagcgctt acctgcaaat ccctttcttt ccaaatccct cttccaacca
    47401 agtttgtgaa ataaaaaata tttgaaataa atttcacaaa cttcaaagat aaaacctgat
    47461 aagaaaagaa gatgagaaaa gtttcacaag agtttaaaaa ttctttgtga aatgtttatg
    47521 aaactgttta caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa ttaacaaagg
    47581 atatcgttcc ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg tgacaccaga
    47641 ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag ctctagttgc
    47701 ccttgaagaa atgcgtaaat tggatcaaga acaagttgac tacatcgttg ccaaagcatc
    47761 agtagcagct ttggatgccc acggagaatt ggctttacat gcctttgaag aaacaggacg
    47821 tggtgtattt gaagataaag caactaagaa cttgtttgct tgtgaacacg tggtaaacaa
    47881 catgcgtcac actaaaacag ttggcgttat cgaagaagat gatgtaacag gattgaccct
    47941 gattgctgaa ccagttggtg ttgtttgtgg tatcactcca acaacaaacc caacatcaac
    48001 agcgatcttc aaatcattga tttcattgaa gacacgtaat ccaatcgtct ttgccttcca
    48061 tccatcagct caagaatcat cagttcatgc agctcgtatc gtccgcgatg cagctatcgc
    48121 agctggtgct cctgaaaact gtgtacagtg gatcactgaa ccatctatgg aagcaactag
    48181 tgcccttatg aaccacgaag gtattgcaac aatccttgca acaggtggta atgccatggt
    48241 taaagccgca tactcatgtg gtaaaccagc tcttggggta ggtgccggaa acgttccagc
    48301 ttatgttgaa aaatcagcaa acattcgtca agcagcacac gatatcgtca tgtctaaatc
    48361 atttgataac ggtatggtct gtgcatctga acaagcagtt atcattgata aagaaattta
    48421 cgatgaattt gtagcagagt tcaaatctta ccacacttac tttgtaaaca aaaaagaaaa
    48481 agctcttctt gaagagttct gcttcggcgt caaagcaaac agcaaaaact gtgctggtgc
    48541 aaaattgaac gctgacatcg ttggtaaacc agcaacttgg attgcagaac aagcaggatt
    48601 tacagttcca gaaggaacaa acattcttgc tgcagaatgt aaagaagttg gcgaaaatga
    48661 gccattgact cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg aaagccgtga
    48721 agatggtatt actaaggctc gtcaaatggt tgaatttaac ggtcttggac actcagcagc
    48781 tatccacaca gctgacgaag aattgactaa agaatttggt aaagctgtta aagctattcg
    48841 tgttatctgt aactcacctt ctacttttgg tggtatcggg gacgtttaca atgccttctt
    48901 gccatcattg acacttggat gtggttctta cggacgcaac tcagttgggg ataacgttag
    48961 tgccattaac ctcttgaata tcaaaaaagt cggaagacgg agaaataaca tgcaatggat
    49021 gaaacttcct tcaaaaacat actttgaacg tgattcaatt caataccttc aaaaatgtcg
    49081 tgacgttgaa cgtgtcatga tcgttactga ccatgccatg gtagagcttg gtttccttga
    49141 tcgtatcatc gaacaactgg accttcgtcg caataaggtt gtttaccaaa tctttgcgga
    49201 tgtagaaccg gatccagata tcacaactgt aaaccgtggt actgagatta tgcgtgcctt
    49261 cagaccagat accatcatcg cactcggtgg tgggtctcca atggatgctg ccaaagtaat
    49321 gtggctcttc tacgagcaac cagaagtgga cttccgtgac cttgtccaaa aattcatgga
    49381 tatccgtaaa cgtgccttca agttcccatt gcttggtaag aagactaaat tcatcgcgat
    49441 tccaactaca tctggtacag gatctgaagt aacaccattt gccgttatct ctgataaagc
    49501 aaacaaccgt aaatacccaa tcgctgacta ctcattgaca ccaactgtgg caattgtaga
    49561 ccctgctttg gtattgacag ttccaggatt tgttgctgct gatactggta tggacgtatt
    49621 gactcacgcg acagaagcat acgtatcaca aatggctagt gactacactg atggtttagc
    49681 acttcaagct attaaattgg tctttgaaaa tctcgaaagc tcagttaaga atgcagactt
    49741 ccactcacgt gagaaaatgc ataacgcttc aacaatcgct ggtatggcct ttgccaatgc
    49801 cttcctaggt atttctcact caatggccca taagattggt gcgcaattcc acacaataca
    49861 cggtcgtaca aatgctatct tgcttccata cgttatccgt tacaacggta cacgtccagc
    49921 taagacagca acatggccta agtacaacta ctaccgtgca gatgaaaaat accaagatat
    49981 cgcacgcatg cttggacttc cagcttctac tccagaagaa ggggttgaat cttacgcaaa
    50041 agctgtctac gaactcggtg aacgtattgg gatccaaatg aattttagag accaaggaat
    50101 tgacgaaaaa gaatggaaag aacattctcg tgaattagcc ttcctggctt atgaagacca
    50161 atgttcacca gctaacccac gtcttccaat ggtagaccat atgcaagaaa tcatcgaaga
    50221 tgcatactat ggctacaaag aaagaccagg acgccgtaaa taattgttta tcagtctaga
    50281 agcaagacaa aaactcaatt tgagggaaag atccagtaat ttttctatga taaaaggcat
    50341 cctatcaagg tttttgaaca cctgatagga tgccttttta tgatattgag gcctttttgc
    50401 cctttttgaa aaactagaat agaaacaaaa tatataatag attgaaactg gaatagtaca
    50461 cttctgcttc taaaacattg ttagaattcg atttgactgt cctgatcgat ttgtcctatt
    50521 cctatttcat tttattatat aaaaaatat
//
LOCUS       DBERAE010000008        48764 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.08, whole genome shotgun sequence.
ACCESSION   DBERAE010000008 DBERAE010000000
VERSION     DBERAE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.08"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            167..781
                     /locus_tag="ACL70N_000627"
     CDS             167..781
                     /locus_tag="ACL70N_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGS0589460.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGNAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAVLRLVF"
     gene            885..1715
                     /locus_tag="ACL70N_000628"
     CDS             885..1715
                     /locus_tag="ACL70N_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS0589461.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1756..1833
                     /locus_tag="ACL70N_000629"
                     /pseudo
     CDS             1756..1833
                     /locus_tag="ACL70N_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            1937..2767
                     /locus_tag="ACL70N_000630"
     CDS             1937..2767
                     /locus_tag="ACL70N_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0589462.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2921..3775
                     /locus_tag="ACL70N_000631"
     CDS             2921..3775
                     /locus_tag="ACL70N_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS0589463.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3875..5248
                     /locus_tag="ACL70N_000632"
     CDS             3875..5248
                     /locus_tag="ACL70N_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGS0589464.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAYFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQRHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            5241..6302
                     /locus_tag="ACL70N_000633"
     CDS             5241..6302
                     /locus_tag="ACL70N_000633"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGS0589465.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEESSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            6304..6996
                     /locus_tag="ACL70N_000634"
     CDS             6304..6996
                     /locus_tag="ACL70N_000634"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGS0589466.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(7026..7595)
                     /locus_tag="ACL70N_000635"
     CDS             complement(7026..7595)
                     /locus_tag="ACL70N_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS0589467.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7730..8344
                     /locus_tag="ACL70N_000636"
     CDS             7730..8344
                     /locus_tag="ACL70N_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS0589468.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFISSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            8322..9992
                     /locus_tag="ACL70N_000637"
     CDS             8322..9992
                     /locus_tag="ACL70N_000637"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0589469.1"
                     /translation="MKNWRQNRMKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKVSPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQ
                     ASYSDQRQSIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            10004..11290
                     /locus_tag="ACL70N_000638"
     CDS             10004..11290
                     /locus_tag="ACL70N_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0589470.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            11351..11884
                     /locus_tag="ACL70N_000639"
     CDS             11351..11884
                     /locus_tag="ACL70N_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589471.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11962..12432
                     /gene="nrdI"
                     /locus_tag="ACL70N_000640"
     CDS             11962..12432
                     /gene="nrdI"
                     /locus_tag="ACL70N_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGS0589472.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12725..13987)
                     /locus_tag="ACL70N_000641"
     CDS             complement(12725..13987)
                     /locus_tag="ACL70N_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGS0589473.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(14297..14755)
                     /locus_tag="ACL70N_000642"
     CDS             complement(14297..14755)
                     /locus_tag="ACL70N_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGS0589474.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14752..15192)
                     /locus_tag="ACL70N_000643"
     CDS             complement(14752..15192)
                     /locus_tag="ACL70N_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0589475.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15625..16491
                     /locus_tag="ACL70N_000644"
     CDS             15625..16491
                     /locus_tag="ACL70N_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0589476.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16644..16772
                     /locus_tag="ACL70N_000645"
     CDS             16644..16772
                     /locus_tag="ACL70N_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589477.1"
                     /translation="MRSLFKKIVAVLVIGLILLGIARTPQVHKMARGIDPGPANFI"
     gene            16828..17385
                     /locus_tag="ACL70N_000646"
     CDS             16828..17385
                     /locus_tag="ACL70N_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavoprotein"
                     /protein_id="HGS0589478.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            17606..18712
                     /locus_tag="ACL70N_000647"
     CDS             17606..18712
                     /locus_tag="ACL70N_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HGS0589479.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGSA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            18688..20079
                     /locus_tag="ACL70N_000648"
     CDS             18688..20079
                     /locus_tag="ACL70N_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589480.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            20076..21254
                     /locus_tag="ACL70N_000649"
     CDS             20076..21254
                     /locus_tag="ACL70N_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0589481.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            21292..21655
                     /locus_tag="ACL70N_000650"
                     /pseudo
     CDS             21292..21655
                     /locus_tag="ACL70N_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032902.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
     gene            21679..21912
                     /locus_tag="ACL70N_000651"
     CDS             21679..21912
                     /locus_tag="ACL70N_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0589482.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            complement(21878..22009)
                     /locus_tag="ACL70N_000652"
                     /pseudo
     CDS             complement(21878..22009)
                     /locus_tag="ACL70N_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_152639374.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            22195..24144
                     /gene="mutL"
                     /locus_tag="ACL70N_000653"
     CDS             22195..24144
                     /gene="mutL"
                     /locus_tag="ACL70N_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGS0589483.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(24469..24936)
                     /gene="ribE"
                     /locus_tag="ACL70N_000654"
     CDS             complement(24469..24936)
                     /gene="ribE"
                     /locus_tag="ACL70N_000654"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGS0589484.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(24937..26142)
                     /locus_tag="ACL70N_000655"
     CDS             complement(24937..26142)
                     /locus_tag="ACL70N_000655"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGS0589485.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(26162..26797)
                     /gene="ribE"
                     /locus_tag="ACL70N_000656"
     CDS             complement(26162..26797)
                     /gene="ribE"
                     /locus_tag="ACL70N_000656"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGS0589486.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(26782..27882)
                     /gene="ribD"
                     /locus_tag="ACL70N_000657"
     CDS             complement(26782..27882)
                     /gene="ribD"
                     /locus_tag="ACL70N_000657"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGS0589487.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(28016..28130)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            28287..28880
                     /gene="ruvA"
                     /locus_tag="ACL70N_000658"
     CDS             28287..28880
                     /gene="ruvA"
                     /locus_tag="ACL70N_000658"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGS0589488.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            28890..29453
                     /locus_tag="ACL70N_000659"
     CDS             28890..29453
                     /locus_tag="ACL70N_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGS0589489.1"
                     /translation="MTKRCSWVKMTNPLYITYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            29450..30127
                     /locus_tag="ACL70N_000660"
     CDS             29450..30127
                     /locus_tag="ACL70N_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0589490.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALIHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(30264..31294)
                     /locus_tag="ACL70N_000661"
                     /pseudo
     CDS             complement(30264..31294)
                     /locus_tag="ACL70N_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
     gene            complement(31549..32232)
                     /locus_tag="ACL70N_000662"
     CDS             complement(31549..32232)
                     /locus_tag="ACL70N_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGS0589491.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(32244..33188)
                     /locus_tag="ACL70N_000663"
     CDS             complement(32244..33188)
                     /locus_tag="ACL70N_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS0589492.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            33320..36151
                     /gene="uvrA"
                     /locus_tag="ACL70N_000664"
     CDS             33320..36151
                     /gene="uvrA"
                     /locus_tag="ACL70N_000664"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGS0589493.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILASVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            36144..37205
                     /locus_tag="ACL70N_000665"
     CDS             36144..37205
                     /locus_tag="ACL70N_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS0589494.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            37337..37735
                     /gene="spx"
                     /locus_tag="ACL70N_000666"
     CDS             37337..37735
                     /gene="spx"
                     /locus_tag="ACL70N_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGS0589495.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            37801..38370
                     /locus_tag="ACL70N_000667"
     CDS             37801..38370
                     /locus_tag="ACL70N_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGS0589496.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            38457..38723
                     /locus_tag="ACL70N_000668"
     CDS             38457..38723
                     /locus_tag="ACL70N_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGS0589497.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            38727..39146
                     /gene="ruvX"
                     /locus_tag="ACL70N_000669"
     CDS             38727..39146
                     /gene="ruvX"
                     /locus_tag="ACL70N_000669"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGS0589498.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            39162..39467
                     /locus_tag="ACL70N_000670"
     CDS             39162..39467
                     /locus_tag="ACL70N_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGS0589499.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            39726..40976
                     /locus_tag="ACL70N_000671"
     CDS             39726..40976
                     /locus_tag="ACL70N_000671"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS0589500.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKDGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMREGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            41060..41515
                     /locus_tag="ACL70N_000672"
     CDS             41060..41515
                     /locus_tag="ACL70N_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGS0589501.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQVQQPAQQN
                     TNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDG
                     DQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            41661..43193
                     /gene="cls"
                     /locus_tag="ACL70N_000673"
     CDS             41661..43193
                     /gene="cls"
                     /locus_tag="ACL70N_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGS0589502.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIMEIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            43271..43414
                     /locus_tag="ACL70N_000674"
     CDS             43271..43414
                     /locus_tag="ACL70N_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589503.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            43451..44989
                     /locus_tag="ACL70N_000675"
     CDS             43451..44989
                     /locus_tag="ACL70N_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGS0589504.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     YFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILY
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            45109..47316
                     /gene="nrdD"
                     /locus_tag="ACL70N_000676"
     CDS             45109..47316
                     /gene="nrdD"
                     /locus_tag="ACL70N_000676"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGS0589505.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTD"
     gene            47328..47468
                     /locus_tag="ACL70N_000677"
     CDS             47328..47468
                     /locus_tag="ACL70N_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589506.1"
                     /translation="MGKYQLDDKGCAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            47512..48018
                     /locus_tag="ACL70N_000678"
     CDS             47512..48018
                     /locus_tag="ACL70N_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589507.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            48011..48601
                     /gene="nrdG"
                     /locus_tag="ACL70N_000679"
     CDS             48011..48601
                     /gene="nrdG"
                     /locus_tag="ACL70N_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGS0589508.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            48609..>48764
                     /locus_tag="ACL70N_000680"
     CDS             48609..>48764
                     /locus_tag="ACL70N_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-triphosphate reductase"
                     /protein_id="HGS0589509.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNPNY"
BASE COUNT        14773 a         8780 c        10534 g        14677 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgcggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggaat gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttgcc ttgattcttt caagcgtagt gacaggtaag gttgggagcc ttcctcaaat
      661 taaatggcta gacttcttag ccgtctttcc aacagcttgg gtagcctttc gctaccgcaa
      721 tctagtcgga acagttctct ttggagtagt cttgattgcc gtcttgcgtt tggtctttta
      781 aatcagccat aaagaaaacc tatcacagat atatatatca tataatggtg taaatgattt
      841 ttttctgtta agactataag gtattctatt ttggaggaaa tgacatgaaa aaaatcgtta
      901 aatactcatc tcttgctgcc ctagggcttg ttgctgcagg tgtgctagca gcttgctcag
      961 gtggtgctaa gaaagaagga caagcagcta gcaagaaaga aattattgtt gcaactaatt
     1021 cttcaccaaa accattcaac tatgaagaaa atggcgaatt gactggttac gagattgaag
     1081 tcgttcgcgc tatctttaaa gactctgaca agtatgatgt caagtttgag aagacagagt
     1141 ggtcaggtgt ctttgcgggt cttgacgctg accgttacca aatggctgtt aacaacatca
     1201 gctacactaa agaacgtgcg gagaaatacc tttatgcagc cccaactgtt aaagacccta
     1261 acgttcttgt agtcaagaaa gacgattcta gcatcaaatc gcttgatgat gttggtggaa
     1321 aatcaacaga agttgttcaa ggaacaacat ctgctaaaca gttagaagac tacaacaaac
     1381 aacactcaga taatccaact atccttaact atactaaagc aaacttacaa caaatcatgg
     1441 gccacttgag cgatggtcag tttgactaca agatttttga taaaatcact gttgaaacag
     1501 tcatcaagaa ccaaggtttg gacaacttga aagtcatcga acttccaagc gaccaacaac
     1561 cttacgttta cccacttctt gctaaaggtc aagatgagtt gaaaacattt gtagacaaac
     1621 gtatccaaga actctacaaa gacggaactc ttgaaaaatt gtctaaacaa ttcttcggag
     1681 acacttacct accggcagaa gctgatatta aataatttct tgaaatcatc cattctgagt
     1741 aagatgggtg atttttcagt tcgctaccgc aatctagtcg gaacagttct ctttggagtg
     1801 gtcttgattg ccatcttgcg tttggtcttt taaattaccc ataaaaaaaa cttatcacag
     1861 agatagatat catataatgg cgtaaatgct ctttttctgt taagattata aggtattcta
     1921 ttttggagga aatgacatga aaaaaatcgt taaatactca tctcttgctg ccctaggact
     1981 tgttgctgca ggtgtgcttg cggcttgctc agggggtgct aagaaagaag gagaagcagc
     2041 tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca aggccattta tctatgaaga
     2101 aaatggcgaa ttgactggtt acgagattga agtcgttcgc gctatcttta aagattctga
     2161 caaatatgat gtcaagtttg aaaagacaga atggtcaggt gtctttgctg gtcttgacgc
     2221 tgaccgttac aatatggctg tcaacaatct tagctacact aaagaacgtg cggagaaata
     2281 cctctatgcc gcaccaattg cccaaaatcc taatgtcctt gtcgtgaaga aagatgactc
     2341 tagtatcaag tctctcgatg atatcggtgg aaaatcgacg gaagtcgttc aagccactac
     2401 atcagctaag cagttagaag catacaatgc tgaacacacg gacaacccaa ctatccttaa
     2461 ctatactaag gcagacttcc aacaaatcat ggtacgtttg agcgatggac aatttgacta
     2521 taagattttt gataaaatcg gtgttgaaac agtgatcaag aaccaaggtt tggacaactt
     2581 gaaagttatc gaacttccaa gcgaccaaca accgtacgtt tacccacttc ttgctcaagg
     2641 tcaagatgag ttgaaatcat ttgtagacaa acgcatcaaa gaactttata aagatggaac
     2701 tcttgaaaaa ttgtctaaac aattcttcgg agacacttat ctaccggcag aagctgatat
     2761 taaataattt cttgaaatca tccattctga gtaaggtggg tggtttctca gtttttaggg
     2821 atatagtttt aaactatata tctgactatc taataacaat ttgtgaaatc aaacaaattg
     2881 tgagatacta gtacggtatt atttttaagg agaaagaatc atgaaaatca aaaaatggct
     2941 tggcctagca gcccttgcta cagtcgcagg tttggctctt gcagcttgcg gaaactcaga
     3001 aaagaaagca gacaatgcaa caactatcaa aatcgcaact gttaaccgta gcggttctga
     3061 agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa gacgggatta ccttggaatt
     3121 tacagagttc acagactatt cacaaccaaa caaagcaact gctgatgggg aagtagattt
     3181 gaacgctttc caacactata acttcttgaa caactggaac aaagaaaacg gaaaagacct
     3241 tgtagcgatt ggagatactt acatctctcc aatccgcctt tactcaggtt tgaatggaag
     3301 tgccaacaag tacactaaag tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa
     3361 tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa tcagctggct tgattaaatt
     3421 ggatgtttct ggaactgctc ttgcaacagt tgccaacatc aaagaaaatc caaagaactt
     3481 gaaaatcact gaattggacg ctagccaaac agctcgttca ttgtcatcag ttgacgctgc
     3541 cgttgtaaac aataccttcg ttacagaagc aaaattggac tacaagaaag cacttttcaa
     3601 agaacaagct gatgaaaact caaaacaatg gtacaacatc attgttgcga aaaaagattg
     3661 ggaaacatca cctaaggctg atgctatcaa gaaagtaatc gcagcttacc acacagatga
     3721 cgtgaaaaaa gttatcgaag aaacatcaga cggtttggat caaccagttt ggtaataaga
     3781 aacagggagg tgggagagag aattccacct cttgcttttg tatagagcac ggagtgtaaa
     3841 gaagactatt cgttcataga aaggtagaga gaatatggtt tttcctagcg aacaagaaca
     3901 gattgaaaaa tttgaaaagg atcatgtagc ccagcattat tttgaggttt tgcgtacctt
     3961 gatttctaag aaatcagtct ttgcccagca ggttggactc aaggaagtcg caaattatct
     4021 gggtgagatt ttcaagcgtg ttggagctga agtggagatt gatgagagct atacagcgcc
     4081 ctttgtcatg gcatatttca agagttcgcg tccagatgcc aagaccttga ttttctataa
     4141 ccactatgac actgtgccag cggatgggga tcaggtctgg acagaggatc cttttacgct
     4201 ttcggtccgc aatggcttca tgtatgggcg tggggttgat gacgacaagg gtcatatcac
     4261 agctcgcttg agtgctttga gaaaatatat gcagcgccat gatgatttac ctgtcaatat
     4321 cagctttatc atggagggag cggaggaatc ggcttcaaca gacctagata agtatttgga
     4381 aaagcatgca gacaaactcc gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa
     4441 tgccttggaa caactggaaa tttctggtgg caataagggg attgtgacct ttgatgccaa
     4501 ggtaaaaagc gctgatgtgg atatccactc gagttatggt ggcgttgtgg aatcagctcc
     4561 ttggtatctc ctccaagcct tacagtctct tcgtgctgcg gatggccgta tcttggttga
     4621 aggcttgtac gaagaagtac aagagcccaa tgaacgagaa atggccttgc tagaaactta
     4681 tggtcaacga aacccagagg aagttagtcg gatttatgga ttggagttgc ctctcttaca
     4741 ggaggatcgg atggcctttc taaaacgttt ctttttcgag ccagcgctta atatcgaagg
     4801 aatccagtct ggttatcaag gtcagggtgt taagactatt ttacctgcag aagccagtgc
     4861 caagctagag gttcgtctgg ttccgggcct agaaccgcat gatgttctgg aaaaaattcg
     4921 gaaacagcta gacaaaaatg gctttgataa ggtagaatta tactatacct tgggagagat
     4981 gagctatcga agcgatatga gcgcaccagc cattctcaat gtgatcgagt tggccaagaa
     5041 attctatcca cagggcgttt cagtcttgcc gacgacagcg gggacaggac ctatgcatac
     5101 ggtctttgat gccctagagg taccaatggt tgcattcggt ctaggaaatg ccaatagccg
     5161 agaccacggt ggagatgaaa atgtgcgaat cgctgattat tacacccata tcgaattagt
     5221 agaggagctg attagaagct atgagtagag atattatcaa gttagatcag atcgatgtga
     5281 cttttcatca aaagaagaga accattacag cggttaagga tgtgaccatt cacatccaag
     5341 aaggggatat ctacggaatc gttggatatt ctggagcagg gaaatcaacc cttgtacggg
     5401 tgattaacct cttgcaaaaa ccatctgcag ggaaaattac cattgacgac gatgtgattt
     5461 ttgatggtaa ggtcaccttg acggcagagc agttgcgtcg taaacgtcaa gatatcggga
     5521 tgattttcca gcattttaac ctgatgagcc aaaagacagc agaggagaat gtagcctttg
     5581 cccttaaaca ctctggactc agcaaggaag aaaagaaggc taaagtagct aagttgttgg
     5641 acttggttgg tttggcagat cgtgctgaaa actacccttc acaactatct ggagggcaaa
     5701 aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg
     5761 agtcaacttc tgcccttgac cctaagacaa ccaagcagat tttggccttg ttgcaagatt
     5821 tgaaccaaaa attaggcttg actgttgtcc tgattacgca tgaaatgcag attgtcaaag
     5881 acattgccaa ccgtgttgca gttatgcagg atgggcattt gattgaagag agtagtgtgc
     5941 ttgaaatctt ctcagaccct aaacaacctt tgactcaaga ctttatctca acagctacag
     6001 gtattgacga agccatggtc aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa
     6061 acagtctctt ggtgcaactc aagtacgctg gatcttcaac agacgagcca cttttgaatg
     6121 aattgtacaa gcattatcaa gtaatggcta atattctcta tgggaatatc gaaatcctcg
     6181 atggtactcc tgttggagaa ttggtggtgg tcttgtcagg tgaaaaagca gcgctggcag
     6241 gtgctcaaga agccattcgt caagcaggcg tacagttaaa agtattgaag ggaggacagt
     6301 aagatggaat cattgattca aacctattta ccaaatgtct ataagatggg ttggtctggt
     6361 caggcaggct ggggaacagc tatctaccta accctctata tgacagttct ttccttcatt
     6421 atcggaggct tcttggggct agtggcaggt ctctttctcg tcttgacagc gccaggtggt
     6481 gtcttggaga ataaagtcgt attctggatt ttagacaaaa ttacctcaat ttttcgtgcg
     6541 gttcccttta tcatcctctt ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca
     6601 agtatcgggc caaatgcagc ccttgtccca ctttcttttg cagtctttgc cttctttgcc
     6661 cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg tcattgaggc ggctcaagcg
     6721 agcggagcga ctttctggga catcgtgggt gtttacctat cagaaggtct tccagatttg
     6781 atccgtgtga cgactgtgac cttgatttcc cttgttgggg aaacagctat ggccggtgcg
     6841 gttggagctg gtggtatcgg taacgtagcc atcgcttatg gatttaaccg ctacaatcac
     6901 gatgtgacca tcttggcaac catcgttatc attttgatta tctttgcaat ccaattctta
     6961 ggagatttct tgactaagaa attgagccat aaataaaaaa gagccgtgtg gctcttttta
     7021 actgatcaga ttttctgggc aaatttttta ctcaaggctt gtccaatcaa ggcacccact
     7081 agggctccga tgacaatact tgcgataaat agaaggacag ttccagggtt tggagcgacc
     7141 atgatgcggt cgatatattc ttgggatttt cctcttgcca gaagagtagc catataggct
     7201 ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa aataatgaaa
     7261 gaaaggaagt tctttgtttt gtccttgtat tttcctaaat gagctactcc atctgctagg
     7321 aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag
     7381 agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt tgcgactagg
     7441 atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa catgtttcca
     7501 gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa gtaaagaact
     7561 gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat aattttttca
     7621 caattctcat tttaccatgg tttggtggga ttgtaaatgg atactagaag tttttgaaaa
     7681 cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca tgggtagatt
     7741 tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct tcttttggct
     7801 attaacttta gcaggaggga ttatccttgg tctagcgccg gctagtgcca ccttgatgag
     7861 cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg cttggtctct
     7921 ttacaagcaa aattttatct caagcaacct gattttctat agctttttag gtgtgggtct
     7981 agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacca ttgttcattt
     8041 gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt atacagtatc
     8101 tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat tatccttgat
     8161 tggcatcttt atgagtctag cagctgtggc taaggttctc cttgggactg tgctacttgt
     8221 agcaattggt tactatatgc ctgccctgct attttttgta ggaattggga tgtggcattt
     8281 ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa
     8341 atagaatgaa gcacttttgg ctacatacgc ttctaagaac ctatagttca gtgatgatca
     8401 ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca cgtgaaaagg
     8461 aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt gaatattacc
     8521 atagagagtc aacccagata gctcaggctt tagttgaaaa ccaagctcgt attgagggaa
     8581 tctataaata ctttagcctt agcatgccag actattttta ctggcaatta gagcggaaag
     8641 tttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat gttcgaaatg
     8701 attttgtaac tggggtggcc attgcttttc aagattacaa ggaagtctat gtttctacta
     8761 aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagca ggaaatagtt
     8821 ttgccattcc agtgtcagat ccagtgtcag atcaagactt aggagtgatt tacatctcct
     8881 tggatcctgc tgttttatac catgccattg ataatactag aggtcatact ccgatggcag
     8941 taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca gttgataagg
     9001 agagtgaaaa ttggctagtt ggcttaactt ctcatggtta tcaggttcag gtggcagttc
     9061 ccaaaaactt tgttttacaa ggaacggtga ccagctctgc tttgattgtg ggcttgagcc
     9121 ttctctttat tgtcattctt tatctgactt tgaggcagac ctttgctaat tatcaaaagc
     9181 aggtagtgga tttggtggat tccatccaag ctattgccca aggacaagaa ggtcttcgca
     9241 ttgatacgct tgaaaaggat caggaattgc tcctaatcgc ggagacgacc aatgatatgt
     9301 tggatcgatt ggaaaagaat atccatgata tttaccagtt agagcttagt caaaaagatg
     9361 ccaatatgcg agccttgcag gcgcaaatca atcctcattt tatgtataat acgctggagt
     9421 tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt ggcagatatc atttatgaat
     9481 tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc aaacaggaat
     9541 tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag tccattgcct
     9601 atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt accttgcaac
     9661 cgctggtaga aaactatttc gcgcatggtg ttgaccacag gcggacagat aatgtgatta
     9721 gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat aatggtagag
     9781 gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaaa tattttgaac
     9841 accaagccag ctacagtgat caaaggcagt ctatcggaat tatcaatgta cacgagcgtt
     9901 ttgtgctcta ttttggagac cgctatgcca ttacgataga gtctgcagag caagccggtg
     9961 ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata aagtattatt
    10021 agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct ttgataagtg
    10081 ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa gctctagaat atgttcagga
    10141 aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag ggcttgatat
    10201 gattcgggag atgaaagaga tcttaccaga tgctgcctat atcctgctct caggttatca
    10261 ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt tggtcaagcc
    10321 tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc tcggcgagag
    10381 agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg ttagttattt
    10441 aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt ccttcaccat
    10501 tccctactat gtcttgggcc aagactggca gattttcatt tctgaccaac ccctagatgg
    10561 tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct ggaagctgaa
    10621 tgctgagaaa accctctttt acggttctgt aaatttgcag cagtctgaga gtctctttgc
    10681 ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa tcgtagaaga
    10741 gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga ttactaaaca
    10801 gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca aagctgatga
    10861 cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat tggttcctta
    10921 tatcaaggaa actctgagca gctttttcgg tcaataccgt atgaatgaaa atgtggtcag
    10981 tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg atatcagtaa
    11041 ggctctcttt atcaatcctg tctatctagg gcagttgatt aagcgtgaaa ccgattcgac
    11101 ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt tgctttcaac
    11161 tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg gatatttcta
    11221 taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac aggtagaaac
    11281 tatactataa gatttgtatt cctttacaaa atgtgctata atataaatat tattattagg
    11341 aggttctatc atgaaaaaga aaccaattta tctatgggtc ttgctaatct tgtctgccct
    11401 tatttcagtt ccgtctctgt ttggaattgt gagtcccttg cctagtaaag aagcccttcg
    11461 tgctgctcag aaacaagttg caggggtcaa tgctcagcaa ttagaagacc agcttaatta
    11521 tacctataga gtagcagaag catctcattc tatttttaat gttgctttga ttgtgctatc
    11581 tactatttta gtggtcgtag cgattgtctt ccttgttcgt aaaaatttgc aatatgcaaa
    11641 ctatacttac gttggctatg ttttgttagc tattattggt tcgatttatg gctatgttgg
    11701 tttacaagac gctgtgcagt tggttcaaga tgagagcatg cgtttgacag tgagtattgg
    11761 ttcaaaagct gttagcattt tctatatcgt catcaatgtt ctcttcctag cccttgtctt
    11821 ctataagatg tggcgacaac agaaagcctt ggcagaagaa gaggaaacag aagagcttgc
    11881 ctaagtattg acaaaaaaga actatcaaga tacaatcttg gtagttgttt tttgattata
    11941 gataaaatca tggaggtaca tatgaagaca atttctttag tttatattag tttgagtggc
    12001 aacactgaaa gttttgtgac gcgcttgaaa gactatctct tgtcccagta caaagggatt
    12061 gaggttcaaa agattcatat caaggatttg gtcaaggaag gcaaaaattt ctacgaaatg
    12121 gaccatccct atgttgcttt tttgccgacc tatctcgaag gtgggaatgg cgtggataac
    12181 ggagatgttg agattttgac gacaccggtg ggagatttta ttgcctatgg taacaatgct
    12241 agtaagtgtt ttggtgtggt tgggtcagga aatcgtaact ttaataacca atactgccta
    12301 acagccaagc aatacagtca acgctttggc tttcctgtat tggctgactt tgaaatgcga
    12361 ggcatgctgg aagatatcaa acatgtcgca gctattatcg cagatttgta tgagttggaa
    12421 aaggagaatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagt cgcaggttgc
    12481 tcaaagcaca gctttgaggt tgcagataga gctgacgtgg tttgaagaga ttctcgaata
    12541 gtataaagtt cttataagag gtggttgaag ttgttcaact gttttttgag tataaacagt
    12601 ctttaagaac gtaaaaaagc ataagttcag gtcttcaaaa ccttgttctt atgcttttta
    12661 tcatagaaat atttgctgaa ttttctcttg aaatgaaacc ttatcttcat ctcgcgcttg
    12721 tcccttaccc tgcttttccg attgcgagtg cgtagataaa gaagatggcg aagccaaaga
    12781 ggaaaatcaa tcccgcaatg gcaaggtgtt tgagccaaga aggaagattt ttgttttcac
    12841 gtgttaccaa ggcgtaattc aaaagagcaa agaaaggtgt tgtcaggaaa gagccaatca
    12901 tggcaaagcg gagcatggtt gaaacctgac cagcgaagaa cttgataatg atgataccga
    12961 tgatagcagt gatggtcatc cagatgttca aagatttacg attatcctct ttttgactga
    13021 ttagcagtcg gagagattcc tgattaacgc gagaatagcc atcgataaca gttataactg
    13081 ttccaaagat acagaggaag gcaataaagg taatcaagta acgggaccat tcgccaagaa
    13141 cagaggcata catgcccacg aattgagaga tgtatttggc tgaagcagct tcaaccgcct
    13201 gccctgtagg atactgaatc agtgctccca gtgccacaaa gaagacggct aggatagctg
    13261 ttccaatata accagtgtta aagtcaaaca gagcgtcttc tgtgttaaag ttgacggtct
    13321 ttctcttttc agctgaccaa agtgaattga tggctgaaat ttcaatagga gccggcatcc
    13381 atcctaggag ggagacgatg aagggcagag ctgccatttg ccaaggtgtc ttctcgacaa
    13441 aatcagaact gtattctgga tgcttgaccg ccgcaatgat aactgcaaga acagtcgcaa
    13501 tggttaaggc agacataatc catttgacca tgccgtctaa aagtttgtag cctccaaaga
    13561 gtagcatagc ccaaatgatt gcaacgagaa tgagggacca ctgagtaatg ctaagtccaa
    13621 tcattgggaa ggcactggcg atgatagctg agcacagaat ggcaacacca gccgtgttga
    13681 ccatagccga aaagacattg aggataaaga aaatccagag atagagtttt cctttttcgg
    13741 cataaccttc aaccaaagtc tttccagtat cagctgtgta ttcagcacca aaacggaaaa
    13801 atggatattt aaagacattg gctaagatga ccaagagaag tagagaccaa ccgtaagaac
    13861 cgccagcttg agttgaggat acaatgtggg aacctccaac agcggcagtt gccattagga
    13921 ttccaggtcc cattgctttt agcttgcttg cccaggttga ttgatttaag gaaatagctt
    13981 gcgacatgat aaatactcct ttttgaattt tcagaataat ctgtatatgt aatctatatt
    14041 ctacaaaaaa ttttggaaaa atgcaagagt attttgaaaa aagatagaaa atttacaaag
    14101 aaaatctgaa ataactgtta tgatatagag gattgaaact agaatagtac acctctgctt
    14161 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttatttca
    14221 tttcactata gtaaggtgca gcaggataaa gaaaatccga gaagtttctt tctcggattt
    14281 gcttattatg aggttcctat tttctatgct ccaagagttg attgatgtga tctacttttt
    14341 tagcctctct tttatagaga atagcccaga tgatgagata gacaatcgca aactcgataa
    14401 tgagctggag gtagaaaatc cagtggaaag ggaaccaacc agcaagagtt gctagtggga
    14461 caaagccagc cagcataagg aagaaatgag tcagagtggc acgaagcatg ctccagtcac
    14521 ggctaaataa gcggttgcca aagttgaaga gcataccgat ggttgcccat ataagtgtgc
    14581 agtagagcaa gaccagggca ccgtgaacct gatgctgatc catcacttgg ccgatgagag
    14641 agtagggatt tagtggtgcg taggtatttg gtgcataaat gagtgaaaag aggatagaga
    14701 ggatgaggcc gataagaaca ccggtagctg catcgtgaaa tacttgtttt ttcatagttc
    14761 taatttctcc ttgatggttt ttagataacg gcgtgaagag taggtgaagc tttcgttttt
    14821 caagaaaatt tctaccagac cgtttggcgt gagcttgagg tgagagatgg aatcgatatt
    14881 gatgatttct gattgggaaa tttggataaa attggttggc aagagtttaa gaacctgata
    14941 gagtcgcaaa tcaatgctgt aggtctgact cgcggtttct gctagaacct tccgattctc
    15001 gatatagaag cgctgaatct tgccaatctc aactagatag acctgatcat cgatttttcc
    15061 tttgattttt tctctttggt ccagattttc tgcgaactcg atgactttct ggactttttc
    15121 ggtttcttga ggtgcttgga caatcagctt ttcctcctcg taagtctcac taatctgtag
    15181 ttctactttc atagttttct ctccttttca gttatacaag gttgtgatca cttcctgtat
    15241 atccttatta aacactattt tatagcccat ggcaaggaac cttgtctatg tggagggatt
    15301 gggctcctat gtggtggagc ttttctgttc tttctgaaat atggtataat agcactaatc
    15361 aatttctagg aaaatagata cggaaagggg ctgaaagaac taggggaaca gttggaatta
    15421 gaaagtgata ggtatgaaaa gtggcgttga agctgaataa gtttataaag cgtttgaatg
    15481 aagaaatgga aagtaaataa gttgacgatg aattacaaaa tagattttat ctacaatttg
    15541 tatctttcaa atcattgatt tgaattttag atttaatcat gttacaatta aaactgaaat
    15601 caaatagaag aggaaaatgc aaacgtgggc acactattag caacaagatt aaaaaataga
    15661 cggaaagaat taaaaatgtc tcagcgagaa ctagctgaag gtatctgtaa acaggggcaa
    15721 atcagtcgat tagagagcgg agagtttacc cctggagcgg atttcctgaa tgcccttgct
    15781 aagaagttaa aagtcagtat ggattatttt tttgatgagc aggttgtaga gaaagttgag
    15841 gagttatcag aatttaagaa attagcacag acatttatta caaatcgcaa ttatgagtct
    15901 ttgaaatata tatatgaatt ggagaatgta aaagctcacc gcctatcttt agcagataaa
    15961 atctacatgg aatggataaa atctctgata gatttttatt tttacggaca gaaagaagat
    16021 gcgattgtac gattagaggg ggtattatca cagttaagtg tatctgattt gaactatctc
    16081 caagtttcaa acaccctatt caatttttat tatgatattg gagatttagg tcgtttcaat
    16141 aaaattcgtg aaaaactaga gtatcaagta aatcacctca atttgagtac aatcgaagag
    16201 ttagaactat ctattaagtt taactacaac gtttgtcgtt atctatggtt acagaaaaat
    16261 attgaagaag ctattactaa aattacagct actataaaac aatgtaaggc ttacagaacg
    16321 aattatcttt tggctgattt gtacttattg atgggaaatg taagtgaaaa tttttcttct
    16381 aaaagttcgg tgaaagaata ttttgagacg gcatattttc tatacaaact tgaggagaac
    16441 atgtcaatga ctctgaaagt tgagcattac attgcagata taacagaata atgaatacgg
    16501 tgttcaagtg agcatcgttt ttcaaaccta gttcagatac aaaaaagtat caaacaaaaa
    16561 aaaataaaaa aacattataa aaacaattga caagctaatt ttgaagtgat aaattaaatg
    16621 caagaaaaca aaaggagagg tatatgagaa gtttgtttaa gaaaatagtt gctgtattag
    16681 ttattggctt aattctgtta ggaattgcga gaacacctca agttcataag atggctagag
    16741 ggattgatcc tggtcctgcg aattttattt agaaatcaat ttctactaat tgagtactaa
    16801 ttgagtatta atgggtaaaa agattgtatg gataagaaaa atttacttgt attggttact
    16861 ggttcggtag gtgccagtaa tgtagataca tacttatatt atataaaaaa attctataat
    16921 gttaaagtga tactttctga aaattctaaa aaatttataa gtaaggaatt aattagttat
    16981 ttttgtgata aagtttatga tgaaatattt gttgaagagg tagttccgca cgtttttctg
    17041 ccatatgaat ctgacttact tcttatttta ccagctacgg caaatgtgat tggcaaaatt
    17101 gctaatggta ttgctgatga tttagttaca gcaactgttt taaactttaa taaaaaaata
    17161 attttttgtc ccaatatgaa ctctactatg tgggacaatc acatagttca aagaaatgta
    17221 tcaattctaa aggagttggg acatatattt ttatttgagt ctaaaaaaac atatgaggta
    17281 ggattgcgta aagcaataga ttcaacatgt tcaatgttac aaccacagtc gttagtaaaa
    17341 gaacttatca aattagaaaa tattgtcctt gaagagggac attaaaaact actgagaata
    17401 ttaaggaggg gaaaaaatgg aaaattcatc aatcgatgta gatatgctgt tggaagaatt
    17461 gacacaagaa gcaatggtcg ttgttgctgt tgataaggac tgttaattta aacttatggc
    17521 aatatatgaa aggttactgg atgttttaaa ttatgcaggc agtagccttt tattatatac
    17581 aaatggataa agtaaggata atacaatgat taataaaaaa atacaacaag ttgttttgga
    17641 atcattacag aattttttga atgggaactt catttcgcct tgtgtagtct atgattttgg
    17701 cttgctggaa actgtacttg atgaatttaa aaatcaaatt cctgtaacat tcaattacca
    17761 acttttttat gccgttaaag caaattcaaa tgagaagata cttgaattct tagtagataa
    17821 aattgatgga gttgatgtgg cgtcattatc tgaattagat gtggctaaaa aatttttccc
    17881 accaactcaa atttctgtta atggttccgc attttcttat gaaactttat ataatctgat
    17941 taaaaaacaa tataaagttg atattaactt tttggaacat cttcaacaat tttccccaaa
    18001 agaatctgtt ggaataagag taacggagcc agatgaactt aataatcgta tgagtcgatt
    18061 tggaataaat atttgcagtg ataattggac tagtaattta caaaatcctt taattacacg
    18121 actgcatttt cattttggag aaaaagatga taaatttatt gttaagttag ataaaatatt
    18181 atttaagtta caagaaatta ataaacttag agaggttaga gaaataaatc ttggaggcgg
    18241 ttttatgaaa ttatttatgg aaaatcgttt gaaagaattt tttctatcac ttatggaaat
    18301 ctataaaaag tacgatattg atagtactgt gactacaata atagaaccag gtagtgcaat
    18361 tacttcattt tctgcctata tgattactag cccagttaat gttagtgagg tgaatgagca
    18421 gcaggttatc acgttagaca catcaatata caccaataca ttatggtttg ttccgcatat
    18481 tattacaacg ttaaattcaa gtagtaaaga gcgttatagt actattctct atggtaatac
    18541 ctgttatgaa catgacaagt ataaaatgaa agtttcgctt ccaaggttaa ctcaaaatag
    18601 cagtatagtg ttttttcctg taggagctta tataaaaagc aatcattcaa atttacatcg
    18661 taatgatttt atgcgggagg tatatttgtg gacaaaaaac ttgacatatt agataaagtt
    18721 aaggaatatt taggaaataa aactactcaa attctggata atcaatataa agaatttttg
    18781 aaacttaatg atataaggcg agcgtttggt atttcagaaa aagtattaaa caattctttt
    18841 aattttacga gtaaagaatt taatgattta attaataacg aaaattattt attcgaatat
    18901 gcatgtagaa ttagagagga atggagaaaa aaatgcttta atcattctta tcgttttcta
    18961 tgctcaccta taattacaga tgattttctt aacacgaaga cattgagaag tagccaaatt
    19021 gaatataaat atgagcgata tttatcgaaa agttcgatag gcgatagagc ggttgatggc
    19081 tttgtttcct tcaatacttt aacagctaat ggtatgtctg ctattaaact atgtcttgag
    19141 atattaaact ctattttctt caagaagaag attgatttat tatattcaac cggatattat
    19201 gaaacaagat ttttattaaa taatcttgct aaatcaggta ttagttgcta tgaggtaagt
    19261 aattgtgaat tggataaaga taaattttat aatgtattca tgatggaacc caatcgagcc
    19321 gatttaacat tacaaaaaac tgatttcaag atagtagaat attttgttaa gtataaaaat
    19381 aattcaataa aagtcgttat tttagatatt tcatatcaag gttctaattt taaattagta
    19441 gaatttttag agaaatttaa atttgcgaat gtaattattt ttgtggtacg atctttgata
    19501 aaattagatc aaatgggatt agaattgaca aatgggggaa taatagaagt gtttattcct
    19561 aatcatttga gaaagttgaa aaattttatt gaagaggaat tcaataaatt tagaaattct
    19621 cacggagcta atctaagcct ctatgaatac tgtttgcttg ataattcttt aactttaaaa
    19681 aatgattgga actattctga tttagttatg aaatttacga gtaattttta tgctgatata
    19741 aaagacttgt tcatggaaaa ttctgatatt gaaatcatcc atgaagaggg agtacctttt
    19801 gtatttttag atttaatagg tgaaggtaaa aaagaatatg aaatgttttt tcaatggtta
    19861 aacttctttt acaaacagct tggaatcaca ttgtatgcta gaaatagttt tgggtttcgg
    19921 aatctaacag tagagtattt tggaattatt gggacagaaa gatatatatt taagatttgt
    19981 ccaggtgttt ataaagggtt aagttattat ttgatgaaat ttttattaaa atctttttca
    20041 aatgaatatt taaaaactac tgatgaggtt aatagatgaa aaatttgata aagttgctaa
    20101 taattagatt gattgttaac ttagcagaca gtgtatttta tatagtagca ttgtggcacg
    20161 ttagcaataa ttattcttcg agcatgttct taggaatatt tattgcagta aattatctac
    20221 cggatttgtt actaatcttt tttggaccag ttattgacag agtaaatccg caaaaaattc
    20281 ttataatatc aattttggtt caattagcag tggctgtaat atttttatta ttattaaacc
    20341 aaatatcatt ttgggtgata atgagtctag tgtttatttc agtaatggct agctccataa
    20401 gttacgtgat agaagatgtg ttgattcctc aagtggtaga atatgataag attgtatttg
    20461 caaattctct ttttagtatt tcgtataaag tattagattc tatttttaat tcattcgcat
    20521 catttttaca ggtggcagta ggatttattt tattggttaa gatagatata ggcatatttt
    20581 tacttgctct atttatattg ttgttgttaa aatttagaac tagcaatgcg aatatagaaa
    20641 acttctcttt caaatattac aagagagaag tgttgcaagg tacaaagttt attttaaata
    20701 ataaattatt atttaaaacc agtatttctt taacgcttat aaactttttt tattcatttc
    20761 agacagtagt tgtaccgatt ttttctattc gatattttga tggtccgatt ttttatggta
    20821 tttttttaac tattgctggt ttgggtggta tattgggaaa tatgctagcg ccaatcgtaa
    20881 taaaatattt aaaatcgaat caaattgttg gtgtatttct ttttttgaac ggctcaagtt
    20941 ggttagtagc aattgttata aaagactata ctttatcact tattttattt ttcgtttgtt
    21001 ttatgtctaa aggagtcttc aatattattt ttaattcgtt gtaccaacaa atacctccac
    21061 atcaacttct tggtagggta aatactacca ttgattctat tatttctttt ggaatgccaa
    21121 ttggtagttt agttgcagga acgcttattg atttgaatat tgaattagtg ttaattgcta
    21181 ttagcatacc ttattttttg ttttcttata ttttttatac ggataatgga ttgaaagaat
    21241 ttagtatata ttagaaatgt ttatgttcat tcaaaagcat aatgactata actgaaaaag
    21301 aaaagtgata tctttaaggt tgttcttctt ggtggtgaga ttcgtgagac aacccaagct
    21361 tttgtcggaa agattaccaa tgctttgatg gataggatgt actttagcaa gatgttttta
    21421 gtggtaacgg tatcgtggat ggacgtgtaa taacctcttc tttcgaggag tattttacta
    21481 aaaaactagc cttggagcgt tccccagaaa cggacttact cattgactct tcaaagattt
    21541 ggggagaaga ttttgcttca tctgttcctt gaaaaaagtc acagcagtca tcacagacga
    21601 tagtactgaa caaaactatg aagagttaga aatttatacg caggtgattg tataaaggat
    21661 ctggaaatag ataagaagtt gattagtatt gacctaggtg gtacaaatat taagattact
    21721 gttctttcaa atgacggtga gattgaaact ttgtggagta ttacaacaga tacaagtgag
    21781 aaaggttctc aaattatatc ggacatcatc agttctatta aaaataaatt gaccgaacgg
    21841 aatattcctg atagcgacct tcttggaatc ggtatgggaa gttgctcatc atactttcct
    21901 tgtaaatcat aggggctata aactctccgt ctacttgtcc tgcaacaatt gaagtctgct
    21961 caaaacgccg tccgctaatc ttttcataga ctttctccct tttaggagcc tagctttcta
    22021 gtttgttctt tgatttttat tgagtatacc actattttac tccctctggc aagggacttt
    22081 gtctatgtgg agggattggg ctcctatgtg gtggagcttt tctgttcttt ctgaaatatg
    22141 gtataatagc actaatcaat ttctaggaaa atagatacag aaaggggctg aaagatgtct
    22201 catattattg aattgccaga gatgctggca aaccaaatcg cggctggaga ggtcattgaa
    22261 cgtcctgcca gtgtggtcaa agagttggta gaaaatgcca ttgacgcggg ctctagtcag
    22321 attatcattg agattgagga agctggtctc aagaaggttc aaatcacgga taacggtcat
    22381 ggaattgccc acgatgaggt ggagttggcc ctgcgtcgcc atgcgaccag taagataaaa
    22441 aatcaagcag atctctttcg gattcggacg cttggttttc gtggtgaagc cttgccttct
    22501 attgcgtctg ttagtgtctt gactctgtta acggcggtgg atggtgctag tcatggaacc
    22561 aagttagtcg cgcgtggggg tgaagttgag gaagtcatcc cagcgactag tcctgtggga
    22621 accaaggttt gtgtggagga tctctttttc aacacgcctg cccgtctcaa gtatatgaag
    22681 agccagcaag cggagttgtc tcatatcatt gatattgtca accgtctggg cttggcccat
    22741 cctgagattt cttttagctt gattagtgat ggcaaggaaa tgacgcggac agcagggact
    22801 ggtcaattgc gccaagcaat cgcagggatt tacggtttgg tcagtgccaa gaagatgatt
    22861 gaaattgaga actctgacct agatttcgaa atttcaggtt ttgtgtcctt gcctgagttg
    22921 actcgggcta accgcaatta tatcagcctc ttcatcaatg gccgttatat taagaacttc
    22981 ctgctcaatc gtgctatttt ggatggtttt ggaagcaagc ttatggttgg acgttttcca
    23041 ctggctgtca ttcacatcca tatcgaccct tatctagcgg atgtcaatgt gcatccaact
    23101 aagcaagagg tgcggatttc caaggaaaaa gaactgatga ctctggtttc agaagctatt
    23161 gcaaatagtc tcaaggaaca aaccttgatt ccagatgcct tggaaaatct tgccaaatcg
    23221 accgtgcgca atcgtgagaa ggtggagcaa actattctcc cactcaaaga aaatacgctc
    23281 tactatgaga aaactgagcc gtcaagacct agtcaaactg aagtagctga ttatcaggta
    23341 gaattgactg atgaagggca ggatttgacc ctgtttgcca aggaaacctt ggaccgattg
    23401 accaagccag caaaactgca ttttgcagag agaaagcctg ctaactacga ccagctagac
    23461 catccagagt tagatcttgc tagcatcgat aaggcttatg acaaactgga gcgagaagaa
    23521 gcatccagct tcccagagtt ggagtttttc ggacaaatgc acgggactta tctctttgcc
    23581 caagggcgag atggacttta catcatagat cagcacgctg ctcaggaacg ggtcaagtac
    23641 gaggagtacc gtgaaagcat tggcaatgtt gaccagagcc agcagcaact cctagtgccc
    23701 tatatctttg aatttcctgc ggatgatgcc ctgcgtctca aggaaagaat gcctctctta
    23761 gaggaagtgg gcgtctttct agcagagtac ggagaaaatc aatttattct acgtgaacat
    23821 cctatttgga tggcagaaga agagattgaa tcaggcatct atgagatgtg cgacatgctc
    23881 cttttgacca aggaagtttc tatcaagaaa taccgagcag agctggctat catgatgtct
    23941 tgcaagcgat ctatcaaggc caatcatcgt attgatgatc attcagctag acaactcctc
    24001 tatcagcttt ctcaatgtga caatccctat aactgtcctc acggacgtcc tgttttggtg
    24061 cattttacca agtcggatat ggaaaagatg ttccgacgta ttcaggaaaa tcacaccagt
    24121 ctccgtgagt tggggaaata ttaaaagtat aaaaaagtct gggaaaaatt ttcaaaatca
    24181 gaaaaacgca taaaatcagg tgttcaaaaa ccttgatttt atgcgtttta tcatagaaat
    24241 atttacttca ttttttccta attcttttcg aaactctttt taaaccacgt cagttttatc
    24301 agtaatctca aaacagtgtt ttgagctaat tttgccagtt ttgtctgtaa catcgaagtt
    24361 gtgttttacc actctgcgac tggtttccta gtttgctcta tgattttcac agagtattaa
    24421 attgcgattt tgccaagttt ctttattcgt ctaaaagtag agtctgttct atgcgtctaa
    24481 tgtacgaatt aggttgacca tttcaatagc tccttgtgca cactcagaac ccttatttcc
    24541 tgctttagta ccagctcgtt ctatggcttg ttcaattgta tctgtcgtta acacaccaaa
    24601 cataacagga atttcgctat ttaaactgat ttgggcgatt cccttagata cctcgctaca
    24661 tacataatca taatgacttg tattccctct aatgacagct cccaagcaga taattgcatc
    24721 atatttttta ctttttgcca tttttgatgc aatcagtggt atttcaaaag ctcctggaac
    24781 ccaggctacc tcgatatctt tctcgtttac attctctctt ttgagattat ctagtgctcc
    24841 agataataat tttgaagtta taaattcatt aaatctcgct acaacaatac ctattttaat
    24901 attgtttgct actaaattac cttcataagt gttcatttat ttttcctcca tatttaaaat
    24961 gtgacccatt cgatttttct ttgtttctaa ataaaaacta tcgtaaggat tggcttctat
    25021 ttcgattgat attctactgg aaatggtaat tccatatttt tctaactgtt caaccttgtc
    25081 aggattattt gtcagtaaat gaagtgactg aagtcccaga tctttaagca tttgtgctcc
    25141 aatatgatat tctcttaaat caccttcaaa gcctaatgca agattggcat caagcgtatc
    25201 catgccttga tcttgtaaat gataggcttt taatttattg ataagtccaa ttcctcgtcc
    25261 ctcctgtcgc aagtaaagta agacacccga accattctca acaatcattt tcatagcttt
    25321 atcgaattgc tgtccacaat cgcaacgtaa agagcctaaa acatctcctg ttaaacattc
    25381 ggagtggacc cgacataata cattggcttc atcctctatg tttcccataa taagagcaag
    25441 atgatgttcc ccatttagtt tatctatata gctaattgct ttgaaattac cgtatctagt
    25501 aggcatattg acagttgaaa ctcgttctac cagctgatca tatacttttc tatattcttg
    25561 taattctttg atggtaatta gtggaatgtt gtgtttcttc gagaactgaa ttaaatcatc
    25621 tgttctcatc attttgccat catgattcat tatttcacaa cataggccac actcttttag
    25681 tccagctaat tttaataaat caacagttgc ttctgtgtgt ccatttcttt ctagaacacc
    25741 accttttttt gcaattaaag gaaacatgtg tcctggcctg cgaaaatcag agggtgttat
    25801 atcttcagct acacacatac gtgcggtcag tcctctttcc tcggcagaaa tacctgtggt
    25861 cgtttcttta taatcaattg aaactgtaaa agcagtctta tgattatctg tattgttttc
    25921 aaccataggt gaaagcatta attgattagc taaactttcg ctcataggca tacaaattaa
    25981 tcctttggca taagtagcca taaaattaac attttctgtt gtagctgctt gtgcagaaca
    26041 aattaagtct ccttcatttt ctctatcctt gtcgtctata acaagaacaa gtcgtccctt
    26101 ctgcaatgct tctaatgctt cttgtatttt tcgatattcc attgactgat tatcctttct
    26161 gctaaaatcc attttgatat aatagttcct tagatatttc tgattttgga gagttatcca
    26221 tcagtttttg cacatattta cctaagatat cattttcaag atttactgta ctcccgactt
    26281 gtttactctt aagaatggtt tgttccaagg tatgagggat aacagatact gaaaagttta
    26341 ctttggagac tttagcgaca gtcagactaa tgccgtcaat tgtaatagat cctttttcaa
    26401 ctattaaatc taaaatttct ttttgtgtgt tgatttgata ccatacagca ttatcatctt
    26461 tttttattga cgagattttt cctgtaccat caatgtgtcc tgtaacgacg tgacccccaa
    26521 gtcgaccgtt gacagataag gctctttcta gattcacctc acttccatgt tttaatagag
    26581 taagagctgt tcgactccat gtttcattca ttacatcaac tgtaaaggat tgatgattga
    26641 aatgagtaac tgtaagacag ataccattta ctgctatact atcgcctaaa tggatatccg
    26701 ttaatatttt tgaggcttta attgatagtt tacaattacg agagtctttc tgtattcttt
    26761 caacttttcc gatttcttca attattcctg tgaacatgga taaatcactt cactttctat
    26821 gagatagtca tttcctattt gagaaaaagc ataaggtttc aatctaatag cgtcatttgg
    26881 caaagaaatg ccttcacctc cgacaggaaa cttggcactg cctccaaaaa tttttggtgc
    26941 aatatatatt ttcagctcat caacaatttg ttgttccaaa gcactccaat tcattagact
    27001 gcccccttct agaactaggc tatcaatctg catgtttcct agatgttgca ttaaactcga
    27061 taagtctata tgattgcctt ttttctttat ggaaagtatt tcacagccat gattttgata
    27121 tagcttcatt ttatttttgt cttcagagga agtggcaatg taagttttaa tatcatttgc
    27181 tgtttttacg attttagagg taagaggagt tcgtaaatgt gtatcgcata tgatacggat
    27241 aggatttttc ccttcctcca atctacatgt cagcaaagga tcgtcttgaa taacagtatt
    27301 gactcccacc ataattgcac taacatagtg tcgtaactga tgcacatgct ttcttgcttc
    27361 ttcttcagta atccatttgg attgatttgt tttagtggct atttttccat ccattgacat
    27421 tgcatatttc ataaaaacat agggtacatg ctgggtaata tactttctaa aactttttat
    27481 taagttaaga cactcatttt ctaaaattcc aacagtaact tgaagattat tttcctcaag
    27541 tatctttact ccttttccag atacaatagg attacagtct aggcttccaa tgactactct
    27601 tgtaatacca ctatcgatta tagcatctat acagggaggt gttttcccga agtgacaaca
    27661 gggttcaagt gttacataaa gcgtcgctcc gacaggggat tttctacagt ttttaagagc
    27721 atttctctca gcatgtgggc caccaaaaaa ctcatgataa ccttgtccga taatgtgatt
    27781 atcttttaca ataactgcgc cgaccatagg attgggattg acgtaaccag cccctttttg
    27841 tgccagtttt attgctaatt tcatatattt tgaatcgctc atctcactac ctccaaaaaa
    27901 atataccttg aataggggac tactcaaggc atacaaaaga aaacttatgc gattaacaaa
    27961 aatgctctga aatgacaagt aatcatttca gagcacgcaa aaagcacaaa tatactttta
    28021 tcttctttca tccagactat actgtcggct ttggaatttc accaaatcat gcctttcggc
    28081 tcgtgggcta taccaccggt agggaattgc accctgccct gaagatagtt attcaattac
    28141 agatgattat agtacttaat tttgaatatg tcaacagata aataccgatt gtttttgata
    28201 tactgtattt gtgataatcg attctcgctc ctcggataaa gaaaatatga tatactagat
    28261 aaacgaaata agagagaagg aacactatgt acgcatattt aaaaggaatc attaccaaaa
    28321 ttactgccaa atacattgtt cttgaaacca atggtattgg ttatatcctg catgtggcca
    28381 atccttatgc ctattcaggt caggttaatc aggaggctca gatttatgtg catcaggttg
    28441 tgcgtgagga cgcccatttg ctttatggat ttcgctcaga ggatgagaaa aagctctttc
    28501 ttagtctgat ttcggtctct gggattggtc ctgtatcagc tcttgctatt atcgctgctg
    28561 atgacaatgc tggcttggtt caagccattg aaaccaagaa catcacctac ttgaccaagt
    28621 tccctaaaat tggcaagaaa acagcccagc agatggtgct ggacttggaa ggcaaggtag
    28681 tagttgcagg agatgacctt cctgccaagg tcgcagtgca agcaagtgct gaaaaccaag
    28741 aattggaaga agctatggaa gccatgttgg ctctgggcta caaggcaaca gagctcaaga
    28801 aaatcaagaa attctttgaa ggaacgacag atacagctga gaactatatc aagtcggccc
    28861 ttaaaatgtt ggtcaaatag gagcagagaa tgacaaaacg ttgttcgtgg gtcaagatga
    28921 ccaacccgct ctacatcacc tatcatgatg aggagtgggg ccagcccctc catgatgacc
    28981 aagcattgtt tgagttgttg tgtatggaaa cctatcaggc aggcctgtct tgggaaacgg
    29041 tactcaacaa acgccaagct ttccgagaag cctttcatag ctatcaaatt cactcagtcg
    29101 cagagatgac tgacactgaa ttggaagcca tgctggagaa tccagctatc attcgaaata
    29161 gagccaagat ttttgctaca cgcgctaacg cccaagcctt tctacagtta caggcagagt
    29221 acggctcttt tgatgcctat ctttggtctt ttgttgaggg gaaaactgtc gttaacgatg
    29281 ttcctgatta tcgccaagcc ccagctaaaa cacccttatc tgagaaatta gccaaagatc
    29341 tcaaaaaacg aggcttcaag ttcacaggcc cagtcgccgt attgtctttt ctacaggctg
    29401 cagggctagt tgatgaccac gagaatgatt gtgagtggaa aggtcttaaa tgatgtctaa
    29461 caaaaataag ggaattctga tttttgcgat tctctataca gtcctctttg tgtttgatgg
    29521 cgttaaattg ctggcttctt taatgccatc tgccattgca aattatcttg tttatgtagt
    29581 tttagcttta tatggctcct tcttgttcaa ggatagattg atccaacaat ggaaggagat
    29641 tagaaagact aaaagaaaat tcttctttgg agtcttaaca ggatggctct ttctcattct
    29701 gatgactgtt gtctttgaat ttgtatcaga gatgttgaag cagtttgtgg gactagatgg
    29761 acaaggtcta aatcagtcta atattcaaag tacctttcaa gaacaaccac tactgatagc
    29821 tgtttttgct tgtgtcattg gacctctggt agaagaatta tttttccgtc aggtcttatt
    29881 gcattacttg caggaacggt tgtcaggttt actaagcatt attctggtag gacttgtttt
    29941 tgctctgatt catatgcaca gtttggctct atcagagtgg attggtgcag ttggttactt
    30001 aggtggaggc cttgcctttt ctattattta tgtgaaagaa aaagagaata tctactatcc
    30061 cctacttgtt cacatgttaa gcaacagcct ctccttaatc attttagcta tcagtatagt
    30121 aaaatgaaat gagaacagga caaatcgatt tctaacaatg ttttagaagt agaggtgtac
    30181 tattctagtt tcaatatact gtaatatgtg atgaaaatgc cagtaatgat accgagaaaa
    30241 aagctgagaa acttttccca gctttatttg ttatagtcaa agagaatgac ttgttcctgt
    30301 gcatctacat gagcatggac cccaaagggt acaattgctc ttggagttgc gtggccgaca
    30361 ttcagattat agacaatcgg gatattgctg tcaatgatat ccaatagtgc ctctttatag
    30421 tcgtcatgga aagtttcatc cataggtttt ccgaccaaga gtccattgat gaccgcgaat
    30481 atgccagtgt cctttaaagt tagcaacatc tttttgaagt cttctggctt aggcttttct
    30541 tcgcttgttt cgagcaagag gattttccct tcccagtctg acaagtcagg gaaaagtttg
    30601 tatttttggc agagttccgt gctatctgcg tatcgagagt tgtcaaagat atcgtagagg
    30661 gattcgaggc aaccaccgag gattttcccc tcgaactggg cacttccttg caacaagtca
    30721 aaacctgtat ttgtatgact gacacgaggt gttcccaggg ccgtgggact aaaatcagtt
    30781 cgttcctcat accaaacgtc actagggcgg atttctgaaa ttcttcccgt ctcaatcaat
    30841 tctttaaagt agtgaaggct ataggctagc atttctttgt ctaattcaca aatgtctgct
    30901 aaaaaggatt gaccataaaa agtcttgatt cctaatttat gcaacatgag gtggttcatg
    30961 gttgtatccg agaagccaag aaaaattttt tgtttgatac ccttttggag ttggtcattt
    31021 tcaaaaagat aaggtagcaa gcgataggca tcgtctccac cgatggcaca taggatcatg
    31081 tcgatctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    31141 tgataaagtc taatcctttt aacgaatggg gcaaaaagat gggattgagt cccagatcct
    31201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    31261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    31321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    31381 tactcttcga aaatctcttc aaaccacgtc agttttattt gcaacctcaa agctgtgctt
    31441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgagt ataactcaaa
    31501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    31561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    31621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    31681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    31741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg gtccatagta
    31801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    31861 aagagtaatc aatccatagc cgaaagcttg atctgccgca aagaaggttg tgagggcgct
    31921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttggatc
    31981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    32041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    32101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    32161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    32221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    32281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    32341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    32401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    32461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    32521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcttc aaggtatttc
    32581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    32641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    32701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    32761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    32821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    32881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    32941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    33001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    33061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    33121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    33181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    33241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    33301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    33361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    33421 aggttcaggg aagtccagtc tggcttttga taccctctat gcggagggac aacgtcgcta
    33481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    33541 agatgccatt gatggtctca gtccagctat ttctatcgac cagaaaacga ctagcaaaaa
    33601 ccctcgctcg acggtgggaa caacgactga aatcaatgac tatctgcgtc tcctctacgc
    33661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    33721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggcctc
    33781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    33841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    33901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    33961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    34021 tatcgacacc atggacgact ctgagttgtt gttctctgag cattatgcct gtccagtttg
    34081 tggttttact gtcccagagt tagagcctcg tctcttctct ttcaatgctc cttttggctc
    34141 ttgtagtgag tgtgacggct tgggcatcaa gctggaggtg gatactgatt tggtagtgcc
    34201 agatgccagc aaaaccttac gtgagggagc gttagcacct tggaatccta tctcatccaa
    34261 ctactatcca aacatgttag agcaggccat gaaagtattt ggagtggcta tggataagcc
    34321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tatgggtcag atggtaagga
    34381 attccatttc cactatgaga atgaatttgg tggcgtgcgc gatatcgaca ttccgtttga
    34441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    34501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    34561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    34621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    34681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    34741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    34801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggcgtcc tctatatcct
    34861 agacgagccg tcaatcggtc ttcaccagag agacaatgac cgcctgattg ccagtctgaa
    34921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    34981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    35041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    35101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    35161 tgaagtgata ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    35221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    35281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    35341 gactattaca gggattgagc atgtcgaccg tttgattgat attgaccaga gccctatcgg
    35401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    35461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    35521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    35581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    35641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    35701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    35761 ggatgtaggg ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    35821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    35881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    35941 tttagctcgc tttgtagacg atggcaatac agtcctcgtc atcgagcaca atctggatgt
    36001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    36061 catcatcgta acaggaactc cagaagaagt agctgccaat gaagccagct atacaggaca
    36121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    36181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    36241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    36301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    36361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gggcttgact cgtatcggtt
    36421 ttgaagatga gatttcagta tcttattacc accgtatgca ggcagctttt gcaggtttgg
    36481 acttgcttcc acaaactcaa tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    36541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    36601 ttatcaaacc aggaaaaact gaaattgaaa ttgccaactt ccttgatttc cgcatgcgtg
    36661 agttgggagc atctagctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    36721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatt accatggact
    36781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    36841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    36901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    36961 ttgaggcagg ttatggcgac tactttactc acggcattgg ccacggtatt ggtctggata
    37021 tccatgagga accctacttt agccagactt ctacagaaac tattaagaca ggtatggcct
    37081 tgaccgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    37141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    37201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    37261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    37321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    37381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    37441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    37501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    37561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    37621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    37681 acgctctgtc cgtaatgtag aaaatgcaga agcacgttta cgtgcagctc tataaacatc
    37741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagagagaa
    37801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    37861 aaaaaagaaa ctggaacagc tacaaaaaca gaaaaggata cgcttcagtc ggcattgcca
    37921 gttattgaaa atgccgagaa gaatacagtt gtaaccaaga ctttggtctt gcccaagtca
    37981 gatgatggta gccagcaaac tcaaaccatt acatacaagg acaagacttt tttgagctta
    38041 acgattcaac aaaaacgtcc agtttctgat gagttgaaga cttatatcga ccaacatgga
    38101 gtggaagaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    38161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    38221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    38281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    38341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    38401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    38461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    38521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    38581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    38641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgt tactacctca
    38701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    38761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    38821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    38881 acaaggtaga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    38941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    39001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    39061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    39121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    39181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    39241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    39301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    39361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    39421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtgatac agtctgggag
    39481 actgtatcag cccaactccc agaaatgggg aagagttgga acgtccagtg aacattttta
    39541 ccccaactct tagaacttga gaagagttgg aacatctagt ggatgttttt agcccatatt
    39601 cacattcata gtagctagtt attagctaac caggtaagag gtcgggacga aaatcctggc
    39661 cttgttttta ttagtaacca tactttaatg cgataattga ttggactttt gtcaaggaga
    39721 tgtgtatgtt tgaagtagaa gaatggctcc atagtcggat tggtttgaat tttcgatcag
    39781 gtttgggccg aatgcagcaa gcggtggatt tgttaggaaa tcctgagcag tcttacccta
    39841 ttatccacgt aacagggact aatgggaaag gatctaccat tgcttttatg agggaattat
    39901 ttatggggca tggcaaaaaa gttgcgacct ttacctcccc tcatatcgtc tctatcaatg
    39961 accgaatctg cattaatggg caacctatag cagacgcaga ctttatccgt ttgactgatc
    40021 aggtcaaaga gatggagaaa acgcttctgc aaactcctgc ccagttgtcc ttttttgaat
    40081 tgctgacctt agttgctttt ctttatttta gggagcagga ggtggatttg gttttattag
    40141 aagtgggaat tggtggctta cttgacacga ccaatgtggt aactggagag cttgctgtca
    40201 tcacctccat tgggcttgac catcaagaaa ccttgggtga tagtctagaa gcaattgcag
    40261 agcagaaagc tggtattttc aaggatggta agaaggcagt gattgcgaaa ttgcctccag
    40321 aagctaggct tgtctgtcag aaaaaagccg aatctttagc tgttaacctt tatcaggcag
    40381 gtcaagattt tttaatgctg aatggtgatt tttcaagctc tttactaaat ctttcacagc
    40441 tgaacatagg cttagaagga gtctatcagc aggagaatgc agccttggcg ttgcaaactt
    40501 ttcttctttt tatgagagaa ggaaaggaag ctgttgatga acaggctgta agaaaggcct
    40561 tggaacagac ccattgggct ggtcgcttgg agcgtattcg cccacagatt tacttggatg
    40621 gtgctcataa cctccctgcc ttgactcgct tggttgagtt tatcaaagaa aaagagcagg
    40681 aaggctatcg acctcaaatc ctctttggat ccttgaaacg gaaggattat caagggatgt
    40741 tgggttatct gactgaaaat ttacctcaag tggaactcaa aatgaccggc tttgactatc
    40801 aagggtcttt ggacgagaca gatgtcacag gttaccatgt aattccctct taccgagaat
    40861 ttatcagcag tttcgaagaa agggcagacg ctcaagactt gctgttcgtt acagggtctc
    40921 tctattttat ctcagaagta cggggctacc tgctggaccg tgagcagata aattgacccc
    40981 cttgtttgaa cttgttatac taggggaatt gctggttaga gaaaatttct ctaaattggt
    41041 agcagaaagg aaattcatca tgaaattaaa aagattcaca ctttctcttg cttctctagc
    41101 aagttttagt ctcttagtag cttgttcaca aagagctcaa caggttcaac agcctgttgc
    41161 tcagcaggtc caacagcctg ctcaacagaa taccaatact gcaaatgcag gaggtaacca
    41221 aaatcaagcg gctccagtac aaaaccaacc tgttgctcaa ccgaccgata ttgatgggac
    41281 ttatactggt caggatgacg gagaccgtat cactttagtg gtaactggaa cgactggtac
    41341 atggactgag ctcgaatctg acggggatca gaaagtcaaa caggttacat ttgattcagc
    41401 aaatcaacgc atgattattg gcgatgatgt caaaatttac actgtaaacg gtaatcaaat
    41461 cgtcgtagat gatatggata gagacccatc ggaccaaatc gttttaacta aataagacta
    41521 tgcaagtaga aagggctgga tttttcagcc tttttacttt tacctagaaa ataatcataa
    41581 atacttgcct tctaccgaat acctgcgtta tactagtatc aattacttgt ttttagcatt
    41641 caaactatca aggaggggat atgaaatata ggaaatttca attattgatg tccaagtatg
    41701 gctttagtct ttcgattatg ctacttgaac tttgtcttgt ttttggtctc tttctttatt
    41761 taggacgcat ggctcccatt ttatggatta ctgtcctcat tctactgagt atcatcacaa
    41821 tcatttcgat agtcaaccgt aatacgactc ctgagaataa ggtaacctgg ttgttagtag
    41881 cctttgtgcc agtatttggt cccttgctct atctgatgtt tggtgaaagg cgattgtcca
    41941 aaaaagaaat caaacaactg aagaagctag gctctatgca tttccaagaa gcaaatagcc
    42001 agctactaaa agagaaatta aaagaaagtg acaaggcagc ttatggagtc atcaagtcct
    42061 tattgagtat ggataccaat gctgacatct atgatcaaac tgcctctaca ttttttccta
    42121 acggagaagc tatgtggaaa aagatggtag aagatcttaa aaaggctgag aaatttattt
    42181 tcttggaata ttacattata gaagaaggtt tgatgtggaa tcgcatacta gatatactag
    42241 agcaaaaggt agctcagggt gtagaggtta agatgctcta tgatgatatc ggctgtatgg
    42301 ctactttaac aggagattat gcacatcgac ttcgtcagct gggcatcgag gcccataaat
    42361 tcaataaagt tattcctcgt ttgacagtgg cttataataa cagagatcat agaaaaatat
    42421 tgattgttga tggtcagata gcctatactg gtggggtcaa tctggcagat gagtacatta
    42481 accacgtcga gagatttggt tattggaagg atagtggaat tcgcttagac ggactagcag
    42541 taaaagccct gacacgctta tttttgacca cttggtacat taatcgagga gaaattagtg
    42601 attttgatca atatcattta gaaaatcatt ctatcccgag tgacggttta accattccat
    42661 acggaagtgg acccaagcca atttttcgag cgcaggtagg gaaaaaagtt tatcagagtt
    42721 taatcaatca agcaacggaa tcggtctata ttacgacacc ttatttgatt atagattatg
    42781 atttaacaga gacaatcaaa aatgcagcta tgagaggggt cgatgttcga attatcaccc
    42841 cttacatacc agataagaag ttcattcagt tagtcacgag aggggcttat cccgaccttc
    42901 tttctgctgg tgttcggatt tatgagtata gtccaggttt tattcatagt aagcagatgt
    42961 tggtagacga agattttgcg gtggtgggga caatcaatct cgactaccgg agcttggtac
    43021 accattatga aaatgcagtc ttactctata aaactccttc tataatggaa atcgcccgag
    43081 attttcgaaa tatatttgca gattctcagg aagtctatcc tcattctatc aaaacgagct
    43141 ggtatcaaaa gcttgtaaaa gaaatcgccc agctattcgc ccctatctta taagaaatct
    43201 agaacttagg atacaaacca gacctatttt tcttgtcttt tacgaataga aagaaagagg
    43261 aggggaattc atgctaacta aggaagaagt gaatgatatg attgagttca aacagacaca
    43321 tttacaccgc tttcgggaaa ttgaaacctt tgtgaaacta tgcaaaaaat cactcaaaca
    43381 gccatcgcaa gctgacaatc ctaggacttt ttgatatact aagacagata aattgaacag
    43441 gagaaacgat atgagtgtgt atggtagagt agaagaagtt cataaggaga atcgtgaacc
    43501 tctagaatac caaatcgaac aagaatcgca tcatcgtgaa tcaagtcgtc ttcctttggt
    43561 gaaaatttta ctatggagta cgcttgtaac ggggataact ctaggagtac cgctattact
    43621 cgacttaatg agtgcacaag aagtgcagga tttttatgca ggttgggcgc ttcatcagac
    43681 agggaagatt tacagcgact attatggaag tcaaggtttg ctttattatt tgctgactta
    43741 cgtgagtcag ggcggatatt tctttgccat ctttgagtgg ttagccttgg tagcaggagg
    43801 atttttcctt tttagatcag cggacacctt gacagagcaa ggagaccaag ctggacatct
    43861 ggtgactatt ttttacatgc tagttacagg tcttgctttt ggtggaggct atgcgactct
    43921 tttagcgctt cctttcttat tcgcagcctt tagtttagtt gcggcttacc taagcaatcc
    43981 aagccatgat aagggatttg tacggattgg gctagctttg gcaggcggat ttttctttgc
    44041 tcccttatca tcgctcctgt ttattgctgt agtgagttta ggcttgttgg tctttaacct
    44101 tgggcataga cgttttgtgc atgggtttta tcagtttctt gcagtggctt taggtttttc
    44161 acttgtcttt tatccaactg cctactatag tgctgcaaca ggaagttttg gggatgcgat
    44221 tagtggtatt cgttatccta ttgacagtat tcgctttgat tttacttcta aaattttaga
    44281 gaatatgttt ttttatggct tgttgtccct tggtttggga tttgtggttt gtatcttttt
    44341 aggtctcttt caatccaaac cctttaaact atacgtcatt tcggttcctg caagtcttgt
    44401 ggtaatttta ggtttgattt tacttttctt ttcacaagag cctctgcacg cttcttattt
    44461 gatggtcgtc ttccctgttt tcctactttt attggtaacc aatattaaga gtcaacagag
    44521 ggggcgtagt gctagaagaa gccgaagaga aacgccagtt agcctatgga gtcgtttctt
    44581 caaaggaaat ctatatctgc tagtttttgg gtttgtctat cttttgtctg ttcctttttt
    44641 gatgaagttt gtcctttatc cagtacctta tcaagaacgt aatcgtcttg ctgatttggt
    44701 aaaagaggag acaaatacgg aagatgctat ctatgcatgg gatgatactg cgactcttta
    44761 tcgtaagagt gagcgcttgt cgccatcggc gattttgtac ccgttgcact atacagcaac
    44821 tgaagaaaat cgtaataagt tacttaatga cttgaaagaa aaacaaccta aggtgattgt
    44881 ggtaaatgac aaggtggtag tctggtctga agtggaaaca ctcttaaaag aaaattacca
    44941 acaagtaaag actgattact cagagtttaa agtctataaa attaaataac caaatcaata
    45001 tcttgtgtat ttttaaaaat tttaggattt ttaacacaag atattgattt ttctttttag
    45061 agtggtataa tactttttag aaagaacatt ttagaaaaga gcatgcatat gattgcacta
    45121 gaagaaaaaa ttacaatttt gccaactctc ttcgtcgaga aacgagatgg gagacgtgtt
    45181 gtatttgatg tggacaagat tgacaaggct ctccacaagg cggctgacaa ggttatggat
    45241 gtgacacccc tggttgaaaa acgcctcaat gatctgactg agcgaattat tacagaaatt
    45301 catagtcgct ttccacaggg aattaagatt tacgaaattc aaaatatcgt agaacatgaa
    45361 ctccttgaag ccaaagaata tgcactggct gaggagtata ttacttatcg gacacagagg
    45421 gattttgagc gctcaaaagc gacggatatc aactttagta ttcataaact tctcaacaaa
    45481 gaccagacag ttgtcaatga aaatgctaat aaagacagtg atgtctttaa cactcagcgt
    45541 gatttgacag cagggattgt tgggaaatca atcggactgc aaatgcttcc taagcacgta
    45601 gccaatgccc accaaaaggg ggatatccac tatcacgatt tggactacag tccctatacc
    45661 cctatgacca actgctgttt gattgatttt aagggtatgt tggaaaatgg ttttaagatt
    45721 ggaaatgcag aggtagagag tcccaagtct atccagactg cgacagcaca gatttctcaa
    45781 atcattgcca acgttgcttc tagccagtac ggtggctgtt cagctgaccg tatcgatgaa
    45841 attttggcgc cttatgcaga gaagaactat caaaaacatc tcaaagatgc agaagagtgg
    45901 gtattgcctg aaaaacggga agattacgct tggaagaaaa cgcaaaagga catctacgat
    45961 gccatgcaat ctcttgagta tgaaatcaat actctcttca cttcaaatgg acaaacacct
    46021 tttacttcgc taggttttgg tctgggaacc agtcgttttg aacgagaaat tcaaaaagct
    46081 attttaaaca ttcgcatcaa gggtcttggt tcagaacacc gtacggctat ctttcctaaa
    46141 cttattttca ctctgaaaag aggccttaat ttagaggaag gaactcccaa ctacgacatc
    46201 aagcagttgg ctcttgagtg tgcaaccaaa cggatgtatc cagatgtttt atcttacgat
    46261 aagattgttg acttgacagg atccttcaag gtgcctatgg gttgccgttc tttcctccaa
    46321 ggatggaagg atgaaaatgg tgtagaagtc aattcaggtc gcatgaatct gggtgttgtg
    46381 acggttaatc tgcctcgtat tgctcttgag tctgaaggtg atatgaataa gttctgggaa
    46441 atcttcaacg agcgaatgaa tatcgcagaa gatgctcttg tttaccgtgt cgaacgcact
    46501 aaagaggcga caccagcgaa tgctcctatc ctttatcagt acggtgcttt tggccatcgt
    46561 ctaggtaaag aagaaagtgt tgaccagctc tttaagaatc gtcgtgcgac cgtttcgctg
    46621 ggctatatcg gcttgtatga agtagcgaca gttttctttg gtaacagctg ggaaagtaat
    46681 ccagatgcta aggaattcac gctagacatc attcacgata tgaaacgccg tgtagaagag
    46741 tggtcagacc aatatggcta ccatttctct atctactcaa caccatccga aagtctgaca
    46801 gaccgtttct gtcgactaga tatagacaag tttggctcta ttcctgatat cacagacaag
    46861 gaatactaca ccaactcttt ccactacgat gttcgtaaaa atccaacacc gtttgaaaaa
    46921 ttggactttg agaaagtcta tccagaagca ggtgcgtcag gtggtttcat ccattattgt
    46981 gagtatccag tccttcagca aaatccaaag gccttggaag ctgtctggga ttatgcttat
    47041 gaccgtgtag gctatctagg caccaatact ccgattgacc gttgctacaa gtgtgacttt
    47101 gaaggggatt ttgaaccaac tgagagaggg tttgcttgtc caaactgtgg caatagcgac
    47161 cctaaaacag tagatgtggt gaagcgaact tgtggctacc taggtaatcc tcaagcaaga
    47221 ccgatggtca acgggcgtca caaggaaatc gctgcgcgtg tcaaacatat gaatggttca
    47281 acgattaaaa tagctgggca tcaagtaaca gattagaaag aaatgaaatg ggaaaatatc
    47341 aactagacga taaggggtgc gcacaagtga cccgttatca cgagaaacac tctaaaggtg
    47401 gagctggtaa gaaagaacgc ttgcttagct tcagagaaca atttttaaac aagaacaaga
    47461 aaaaataaaa gtgagagcca gctctcgctt ttctcatagt gggaggtaag gatggaatta
    47521 cgcagaccaa gattagcgga taagaaagct gttttagata tgatgacaga gtttgaaaaa
    47581 tttcagtcgc ctcacgacgg cggtttctgg gatacagaga actttgtgta tgaagactgg
    47641 ttagaaagca atcaggaaca ggaaatgggg attaatctgc ctgaaggatg ggttcctgca
    47701 attcagttag tggctttttc tgagaaaggt caagcagttg gatttcttaa tctccggttg
    47761 cgcctcagta actttctact agaagaaggt ggccacattg gctactccat tcgtccatct
    47821 gaaagaggca agggttatgc aaaagagact ctccgtcagg gcttgcaagt tgctaaggaa
    47881 aagaacatca agaaagctct ggtgacctgt agcgtgaata atcctgctag cagagcagtc
    47941 attctagcaa atggtggaat atttgaggat gctcgcaatg gagtcgagcg ttattggata
    48001 gaggtagcga atgaataatc caaaaccaca agaatggaaa agcgaggaac ttagtcaagg
    48061 tcgtatcatt gactacaagg cctttaactt tgtggacggc gaaggcgtgc gtaactctct
    48121 ctatgtatca ggctgtatgt ttcactgcga gggatgttat aatgttgcga cttggtcttt
    48181 taatgctggc attccctata cagcagaatt agaagagcag atcatggcag atcttgctca
    48241 gccctatgtt caaggtttga ctttgttggg aggggagcct tttcttaata ctgggattct
    48301 cttgccactt gttaagcgga ttcggaagga attgccagac aaggacatct ggtcctggac
    48361 cggctacact tgggaagaaa tgatgttgga aactccagat aaactggaat tcttgtcact
    48421 gattgacatt cttgtcgatg gaagatatga tcgaactaag agaaatctta tgctccagtt
    48481 tcgaggttca tctaaccaac gaattatcga tgtgcaaaaa tcgctcaaaa gtgggcaagt
    48541 agtgatttgg gacaagctca atgacggaaa agaaagctat gaacaggtga agagagaatg
    48601 aagaaaaaat gaagaaaaaa gacttagtag accaactagt ctcagagatc gagacgggga
    48661 aagtcaggac actgggaata tacggtcatg gagcttcagg taaatcaacc tttgcacagg
    48721 aattgtacca agctttagat tctactacag taaaccccaa ttat
//
LOCUS       DBERAE010000009        46589 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.09, whole genome shotgun sequence.
ACCESSION   DBERAE010000009 DBERAE010000000
VERSION     DBERAE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 46589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.09"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(612..1025)
                     /gene="ndk"
                     /locus_tag="ACL70N_000681"
     CDS             complement(612..1025)
                     /gene="ndk"
                     /locus_tag="ACL70N_000681"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGS0589510.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="ACL70N_000682"
     CDS             complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="ACL70N_000682"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGS0589511.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="ACL70N_000683"
     CDS             complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="ACL70N_000683"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS0589512.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8873..8943
                     /locus_tag="ACL70N_000684"
     tRNA            8873..8943
                     /locus_tag="ACL70N_000684"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8905..8907,aa:Cys,seq:gca)
     gene            complement(9141..10472)
                     /locus_tag="ACL70N_000685"
     CDS             complement(9141..10472)
                     /locus_tag="ACL70N_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGS0589513.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10763..11587)
                     /gene="endA"
                     /locus_tag="ACL70N_000686"
     CDS             complement(10763..11587)
                     /gene="endA"
                     /locus_tag="ACL70N_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGS0589514.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11626..11814)
                     /locus_tag="ACL70N_000687"
     CDS             complement(11626..11814)
                     /locus_tag="ACL70N_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS0589515.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11807..13090)
                     /gene="murA"
                     /locus_tag="ACL70N_000688"
     CDS             complement(11807..13090)
                     /gene="murA"
                     /locus_tag="ACL70N_000688"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS0589516.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13114..13344)
                     /locus_tag="ACL70N_000689"
     CDS             complement(13114..13344)
                     /locus_tag="ACL70N_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGS0589517.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13402..14439)
                     /locus_tag="ACL70N_000690"
     CDS             complement(13402..14439)
                     /locus_tag="ACL70N_000690"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGS0589518.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="ACL70N_000691"
     CDS             complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="ACL70N_000691"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGS0589519.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="ACL70N_000692"
     CDS             complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="ACL70N_000692"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGS0589520.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15505..16497)
                     /gene="asnA"
                     /locus_tag="ACL70N_000693"
     CDS             complement(15505..16497)
                     /gene="asnA"
                     /locus_tag="ACL70N_000693"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGS0589521.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16608..17291)
                     /locus_tag="ACL70N_000694"
     CDS             complement(16608..17291)
                     /locus_tag="ACL70N_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGS0589522.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17347..18087)
                     /locus_tag="ACL70N_000695"
     CDS             complement(17347..18087)
                     /locus_tag="ACL70N_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGS0589523.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18121..18399
                     /locus_tag="ACL70N_000696"
     CDS             18121..18399
                     /locus_tag="ACL70N_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGS0589524.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18477..19403
                     /gene="yidC"
                     /locus_tag="ACL70N_000697"
     CDS             18477..19403
                     /gene="yidC"
                     /locus_tag="ACL70N_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS0589525.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="ACL70N_000698"
     CDS             complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="ACL70N_000698"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGS0589526.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20398..21648)
                     /locus_tag="ACL70N_000699"
     CDS             complement(20398..21648)
                     /locus_tag="ACL70N_000699"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGS0589527.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21715..22542)
                     /gene="purR"
                     /locus_tag="ACL70N_000700"
     CDS             complement(21715..22542)
                     /gene="purR"
                     /locus_tag="ACL70N_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGS0589528.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22809..23750)
                     /locus_tag="ACL70N_000701"
     CDS             complement(22809..23750)
                     /locus_tag="ACL70N_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGS0589529.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(23740..24996)
                     /gene="rmuC"
                     /locus_tag="ACL70N_000702"
     CDS             complement(23740..24996)
                     /gene="rmuC"
                     /locus_tag="ACL70N_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGS0589530.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24998..25660)
                     /locus_tag="ACL70N_000703"
     CDS             complement(24998..25660)
                     /locus_tag="ACL70N_000703"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGS0589531.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25623..26279)
                     /gene="rpe"
                     /locus_tag="ACL70N_000704"
     CDS             complement(25623..26279)
                     /gene="rpe"
                     /locus_tag="ACL70N_000704"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGS0589532.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="ACL70N_000705"
     CDS             complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="ACL70N_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGS0589533.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="ACL70N_000706"
     CDS             complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="ACL70N_000706"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGS0589534.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28293..28574)
                     /locus_tag="ACL70N_000707"
                     /pseudo
     CDS             complement(28293..28574)
                     /locus_tag="ACL70N_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28567..29208)
                     /locus_tag="ACL70N_000708"
     CDS             complement(28567..29208)
                     /locus_tag="ACL70N_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589535.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29210..31240)
                     /locus_tag="ACL70N_000709"
     CDS             complement(29210..31240)
                     /locus_tag="ACL70N_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS0589536.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31317..31613)
                     /locus_tag="ACL70N_000710"
     CDS             complement(31317..31613)
                     /locus_tag="ACL70N_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS0589537.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31933..32832)
                     /locus_tag="ACL70N_000711"
     CDS             complement(31933..32832)
                     /locus_tag="ACL70N_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0589538.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="ACL70N_000712"
     CDS             complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="ACL70N_000712"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGS0589539.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33464..34237)
                     /locus_tag="ACL70N_000713"
     CDS             complement(33464..34237)
                     /locus_tag="ACL70N_000713"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGS0589540.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPMIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34542..35435)
                     /locus_tag="ACL70N_000714"
     CDS             complement(34542..35435)
                     /locus_tag="ACL70N_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGS0589541.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEVTPEY
                     KLETTPGGDKGGNIGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="ACL70N_000715"
     CDS             complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="ACL70N_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGS0589542.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35998..37212)
                     /locus_tag="ACL70N_000716"
     CDS             complement(35998..37212)
                     /locus_tag="ACL70N_000716"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0589543.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37368..37661)
                     /locus_tag="ACL70N_000717"
     CDS             complement(37368..37661)
                     /locus_tag="ACL70N_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589544.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37810..38262
                     /locus_tag="ACL70N_000718"
     CDS             37810..38262
                     /locus_tag="ACL70N_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGS0589545.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38297..39685)
                     /locus_tag="ACL70N_000719"
     CDS             complement(38297..39685)
                     /locus_tag="ACL70N_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0589546.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELHRQL
                     KAYERHKERNKS"
     gene            39751..40713
                     /locus_tag="ACL70N_000720"
     CDS             39751..40713
                     /locus_tag="ACL70N_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGS0589547.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HTLDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLTMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40710..40901)
                     /locus_tag="ACL70N_000721"
     CDS             complement(40710..40901)
                     /locus_tag="ACL70N_000721"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589548.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     NHTYGKATLTWFAEIFEEY"
     gene            complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="ACL70N_000722"
     CDS             complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="ACL70N_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGS0589549.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42400..42999)
                     /locus_tag="ACL70N_000723"
     CDS             complement(42400..42999)
                     /locus_tag="ACL70N_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0589550.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVAVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(43001..44098)
                     /locus_tag="ACL70N_000724"
     CDS             complement(43001..44098)
                     /locus_tag="ACL70N_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0589551.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(44098..44835)
                     /locus_tag="ACL70N_000725"
     CDS             complement(44098..44835)
                     /locus_tag="ACL70N_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589552.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44837..45721)
                     /locus_tag="ACL70N_000726"
     CDS             complement(44837..45721)
                     /locus_tag="ACL70N_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589553.1"
                     /translation="MDMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELVAFFQSIY
                     PNPLSNQEIDQLLQFDKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(45708..45902)
                     /locus_tag="ACL70N_000727"
     CDS             complement(45708..45902)
                     /locus_tag="ACL70N_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589554.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQALLRQFIRGAWGLGFM
                     IFIAFPMGMEWLKGEYHGHD"
     gene            complement(45899..46090)
                     /locus_tag="ACL70N_000728"
     CDS             complement(45899..46090)
                     /locus_tag="ACL70N_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589555.1"
                     /translation="MKNKMIVAMSLVAAGVMTYLMFSGLDEDFYHFPWELFAGFGMMS
                     WLIREGLKLVSDVKKEFEK"
BASE COUNT        13335 a        10803 c         8834 g        13617 t
ORIGIN      
        1 tattccatgt tattttgagg aagatattgt gaaagtcaaa gatgatgata aagttgagtg
       61 gaatttgtta gaatttcaaa aatttagagc atttttgact tagtaatctg tgttgaaggc
      121 tcaaaaccta tggtaaaaaa gtaactttga aaacgtattg cctccaaaga tttagttaaa
      181 taatgattta acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga
      241 gaaaaggtgg gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata
      301 gtcaattgaa acaagaacag gataaaagaa ccttttgtgc catatttttc tcctttcgct
      361 ttacaattgg attgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc
      421 gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta
      481 atagtcactt aatcaaaaaa cgcaccatat caaaaactaa aaagtttgat atcatgcgtc
      541 atgtcttaaa ctaattgact atactttcta ttcaaatgag cttttaacca attgattgag
      601 ccaatccact cttaaaacca aagagcaatt tctcgcttag ctgactcttc tgaatctgaa
      661 ccatgtacaa cattttggat aacctcattt tctccagcag cttttgcaaa gtcacctcga
      721 atagtgcctg gtaaagcttc ttctggacga gttgcaccca tcatggtccg ccaagtttcg
      781 attactttgg gaccagaaat gacacccaca agaactggac ctgaagtcat gaattcacga
      841 atcggtgggt aaaaactctg accaaccaag tcctgatagt gctggtcaat caactcttct
      901 gaaacctgtg aacgaaactc caatttttcg attgtaaatc cacgttgttc gatgcgcttt
      961 aacacttcac ccactagccc tctttttaca ccatctggtt tgatgataaa gaatgtttgt
     1021 tccatacccg tctcctttgt cagcttcttt cttttatttt accacatttc gtggaaaaat
     1081 ggagaaagtt ttcagaagag agaatgagag aacccgaggg ttctctcatt ctctcttatt
     1141 ctactgtttc ttccacagtt tcaacggcag tatccacaac tacttctgtt gtttcttcat
     1201 ttccttcttc ctctactgga ggattaaggt attcttcttc gttgacagca tgtggttcaa
     1261 ggttacggta acgggccata ccagtaccag ctgggatgat cttaccgatg ataacatttt
     1321 ctttaagtcc aaggagatgg tctttcttac cacggatagc tgcgtcagta aggacacgag
     1381 ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt ttcaagtgag gctttggtaa
     1441 ttcccataag gactgggcga cctgtcgctg gaactccacc tgcgataagg acatctttgt
     1501 tggcatctgt aaagtcattg atatccatga gggtacccat gagaagatct gtatcacctg
     1561 gatccatgac acggacttta cggatcattt gacgaaccat tacctcgatg tgtttgtcac
     1621 cgatttctac cccttggcta cggtaaactt tttgtacttc accgagaagg tacgtttcaa
     1681 ctgacaagac atcacgaact gcaaggagac gttttggttg gatagaacct tctgtcagag
     1741 cagcaccacg cgctacttgg cccccaactt cgacacgcat acgagctgta aatggaacga
     1801 catattcacc ttcgccagtt tcacccttaa caaagacttt cttggtacga gttgatgcat
     1861 cctcttcgat agcagtaact tgtcctttaa cctctgtgat aaccgcttcc cctttaggat
     1921 tgcgggcttc aaagatttct tggacacgag gaagaccctg agtgatatcg gtatttgagg
     1981 caaccccacc tgtgtggaag gtacgcattg taagctgtgt accaggttcc ccgatagatt
     2041 gggcagcgat tgtaccaact gcttcaccaa cttcaaccgc atcaccagtc gccaagttga
     2101 taccgtaaca gtgacggcag acaccgtgac gagtgttaca tgtaaataca gaacggatag
     2161 tcacttcttc cacaccagca ttgacaattt cacgcgcctt gtcttctgta atcaattcat
     2221 ttggaccaat aatcactgca ccagtttctg gatgtttaac agttttctta gtgtaacgac
     2281 cgttgagacg ctcttcgaga gactcgatca tctcttttcc ttctgcgata gaacggatca
     2341 agagaccacg gtcagttcca cagtcgtcct cacggatgat aacgtcttgg gcaacgtcga
     2401 ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag ggccgtatcg gtcatacctt
     2461 tacgagcacc gtgagttgag aagaacattt ccaataccga caaaccttcg cggaagtttg
     2521 aaaggattgg caattccatg atacgtccat tcggagcagc catcagacca cgcataccgg
     2581 caagctgtga gaagtttgag atgttaccac gggctccaga gtccatcatc ataacgattg
     2641 ggttcttagg atcttgatta gcaatcaagc gtttctcaag tttttcacgg gcagcacgcc
     2701 attcagctgt aacagcattg taacgctcgt cgtctgtgat cataccacga cggaattgtt
     2761 tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat ttcagccttg tcatcaacga
     2821 ctgggatatc ggcaataccc actgtcaatc ctgcaagagt tgagtggtgg taaccgaggt
     2881 tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg gaaacgtttg aagatttcag
     2941 cgatgatatt tccgaggttt ttcttcttga atggagggtt gagctcaaga ttgctgatag
     3001 cttccttgat atctccacca agtggcaaga agtatttagc tggaacacct tctgtcaagt
     3061 tggcattgtt tggttcttgc aagtatggta gcccctctgg catgatatcg ttgaagagaa
     3121 ttttaccaac tgttgtaagc aagaccttat gtctttgctc ttctgtccaa ggcttgttga
     3181 ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac ataaccattg cggtaagcca
     3241 taaccgcttc gtcacggtct ttgaagacca ttccttcacc ttcgcgacca gcttcttcca
     3301 tggtcaagta gtagttaccc aaaaccatgt cctgagatgg agtaactacc ggtttcccat
     3361 ctttcgggtt caagatgtgc tcagcagcta gcatgaggat acgagcttct gcttgtgctt
     3421 cttctgaaag tggtacgtgg atggccattt ggtccccgtc aaagtcagca ttgtaggctt
     3481 cacagacaag tgggtgcaag cgaagagcct taccatcaat caagactggc tcgaaggctt
     3541 ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag cactgggtgt tctttaatca
     3601 cttcttcaag gatatcccag atacgctcat ctccgcgttc caccaagcgt ttagctgctt
     3661 tgacgttttg cacgatatca cgggcaacga tttcacgcat gacaaatggt ttaaagagtt
     3721 caatcgccat ttcacgtgga acaccacatt ggtacatctt aagagttgga ccaacggcga
     3781 taacggaacg tcctgagaag tcaacacgtt taccgagcaa gttttgacgg aagcgtccct
     3841 gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg gctacctggt cctgtgattg
     3901 gacgaccacg acgaccattg tcaatcaaag cgtcaactgc ttcttgaagc atacgcttct
     3961 cattttgaac gatgatacct ggtgcattta actcaagcaa acgagccaaa cggttgttac
     4021 ggttgataac acggcggtaa aggtcattca agtcagatga ggcaaaacgg ccaccatcca
     4081 actgcaacat tggacgaaga tctggtggga taaccggaag gatgttaaga atcatccatt
     4141 caggtttgtt tccagacttg taaaaggcat ccaaaacatc caaacgacgg atggctttga
     4201 cacgtttttg tccagtagct gttttcaatt cttctttgag ttcagcaatt tctttttcaa
     4261 gatctacttg cttcaaaagg tcttggatgg cttccgcacc catcttggca acaaatgaac
     4321 cataaccata ttcacgcaag cgctctcggt attcgcgctc tgtcatgata gacttgtgct
     4381 caagtggtgt atccttagga tcaatcacca cataagccgc aaagtagata acttcctcga
     4441 gggcacgagg gctcatatca agggtcaagc ccatacggct tggaatcccc ttgaagtacc
     4501 agatgtgaga tacaggagct ttcaattcga tatgtcccat acgctcacga cgaactttcg
     4561 tacgcgttac ttcaacccca cagcggtcac aaacaattcc tctgtaacga atgcgtttgt
     4621 acttaccaca agcacattcc cagtcttttg taggaccaaa gatcacttca tcaaagagtc
     4681 cttcacgttc tggtttcaag gtccgataat tgattgtttc aggttttttg acttctccat
     4741 aagaccatga acggacttta cttggagaag ctagggtgat ttgcatactt ttaaaacgat
     4801 ttacatcaac cactatttct tccctttcta ttctaagtga actgcttatt cttgttcagc
     4861 agcttcttct gttgcttccg cttttgttgc tttctcagct tcttcagctt caaaggctgc
     4921 tttagcctct tgggctgctt tttcgcgggc tttttcaagg tcatctacgt ggatgacatc
     4981 ttcgtccatt ccttcatcca agtcgcgaag ttccacttct tggtcatctt cgtctaggac
     5041 acgcatgtca agaccaagag attgcaattc tttgacaaga actcggaagg attctggaac
     5101 acctggtttt ggaattggtt tgccttttgt aatagcttca taggctttca aacgtccgtt
     5161 gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca tttgacgcac cgtaggcttc
     5221 aagagcccaa acctccatct caccgaaacg ttgtccacca aactgagctt tacctccgag
     5281 tggttgttgg gtaacagttg agtaaggtcc gactgaacgc gcatgcaatt tatcgtcaac
     5341 catgtggtgg agtttaatca tgtacatgac tccaacagaa acacggttat caaatggttc
     5401 acctgtacgt ccatcgtaaa ggattgtctt ggcatcgcta tccatacctg cttctttaac
     5461 agttgaccaa agatcttcag agcttgctcc atcaaagact ggtgtcgcaa tgtgaatacc
     5521 aagagtacga gctgccatac caaggtgaag ctccataacc tgaccgatat tcatacgtga
     5581 tggcacccca agtgggttca acatgatgtc gactggagtt ccgtctggaa ggtaaggcat
     5641 gtcttctaca ggaacgatac gagagacaac ccctttgttt ccgtgacgtc cggccatttt
     5701 atctccgacc ttaatcttac gtttttgagc gatgtaaaca cgaaccaaca tgttaacacc
     5761 tgattgcaac tcatctccat ttacacgtgt aaagatctta acatcacgaa cgacaccatc
     5821 ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca cgagacttgt ctccaaagat
     5881 agcgtgcaag agacgttctt cagctgaaag atctttctca cccttaggtg ttactttacc
     5941 tacaagaata tcaccttctt taacctcagc accaatacgg ataatcccca tttcgtcaag
     6001 gtctttgagg gcatcttcac caacgtttgg aatttcgcga gtgatttctt caggcccaag
     6061 ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga acagatgtgt agacatcgtc
     6121 cttcaccaaa cgttcgctca tgataacggc atcctcgaag ttgtaacctt cccaagtcat
     6181 gtaggcaacg attgggtttt gtccaagcgc catttctcca ttttccatag aaggtccgtc
     6241 agcgatgaaa tcgccttttt caacgacatc accaactttt acgagagtgc gttggttgta
     6301 agcagtacct gagtttgaac gacggaattt ttggatgtgg taaacatcca atgaaccatc
     6361 ttcacgacga acttctacct tgtcagcatc tgcgtaagta actttaccat catactgagc
     6421 aatcacagcc gcaccagaat cgtgggctgc ttggtattcc ataccagtac caacgtaagg
     6481 tgcctgagga ttaatcaatg gcacagcctg acgttgcata ttggctccca tgagggcacg
     6541 gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacctgttt
     6601 tggtgaaacg tccatgtagt caacaatatt agctggatac tcttggttga ccccttggtg
     6661 acgtcccatg acaatcttct cagcaaaggt tccatcttca ttcagacgag agttagcctg
     6721 agctacagta tattcatctt cttcatcagc tgtcaaccaa acaatttcgt tcgtgacaac
     6781 acctgtttca cggtcaacct tacggtatgg tgtttgaaca aaaccatatt tgttcaagtg
     6841 tccgtaagat gacaagttat tgatcaaacc gatgttaggt ccttcaggtg tctcgattgg
     6901 acacatacga ccatagtgag tgtagtgcac gtcacgtact tcatatccgg cacggtcacg
     6961 agtcaaacca ccaggtccta aggctgacaa acggcgtttg tgagacaact cagaaagcgg
     7021 gttgtgttgg tccatgaact gtgacaactg tgatgaacca aagaattctt taactgcagc
     7081 tgttacagga cggatattga taatttgttg tggtgtcaag acttcattgt cctgaacaga
     7141 catacgttca cggacattac gttccatacg agaaagtccc aaacgtactt ggttggcaag
     7201 caattcacca accgcacgga tacgacgatt tccaaggtgg tcgatatcat ctacacggcc
     7261 aagtccttca gccaagttga ggaagtagct catctcagca aggatatctg caggagtcac
     7321 cgtacgaacc ttgtcatctg ggttagcatt accaatgatc gttacgacgc gatctggatc
     7381 agttggagca ataaccttga atttttgaag aacaacaggc tcagtcacaa cggctgcatc
     7441 gtttgggatg tagacaatct tgttcaagtc gccatccaaa tggctttcaa tgctttcaat
     7501 cacgctacga gtcataatcg taccagcttc taccaagatt tctccagttt cagggtctac
     7561 caatggctct gcaatggttt ggttgagcaa acgtgtttta acattgagtt ttttattgat
     7621 tttgtaacga ccaactgctg ccaagtcata acgacgtggg tcaaagaagc gagctacaag
     7681 caagctacgt gagctttcag ccgtcttagg ctcacctgga cgaaggcgtt cgtaaatttc
     7741 tttcaaggct tcgtctgtac gagagtccat tggattcttg tggatatctt tttcaacagt
     7801 gttgcgaacc aattcgctgt ctccaaagat atcaaagatt tcatcatcac ctgagaaacc
     7861 aagagcacga accaaggttg taaatggaat cttacgagta cggtcgatac gagtgtaggt
     7921 gatatctttt gagtcgcttt caagttccaa ccaagctcca cggttaggga taacagttga
     7981 accatagccc accttaccat ttttgtctac tttgtcgtta aagtaaacac ctggtgagcg
     8041 gaccaactga gaaacgataa tacgttcacc accattgatg atgaaagtac ccatttctgt
     8101 catgattggg aaatcaccaa agaaaacttc ttgggtcttg atttcgcctg tttctttatt
     8161 gatcaaacgg aaggttacaa aaattggtgc tgagtagcta gcatcgtgga tacgagcttc
     8221 ttctagcgtg tattttggtt ccttgatttc atatccaaca aattccaact ccattgtgtc
     8281 tgtgaagttt gaaattggca atacatcttc aaacacttcc ttaagaccgt ggtctaggaa
     8341 agctttgaat gagtcagttt gaatttcaat caaatttggt aagtcaagaa cttctttgat
     8401 tcttgaaaaa ctacgacggg tacgatgttt cccgtattga acgtcatgtc ctgccaagat
     8461 gattctcctt tgtaaataag ttccaagcct tgtcaatcag gcttttctaa tcgtcatatg
     8521 gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt cagaatcttt aagcctctgt
     8581 tacaaatgct cataatcttg aaaaaaagca caaaaagagc agctaaatct gactttttca
     8641 gaagatttaa ctgctgtgag ccttgtctgg acaatatttc agacaaaacc tacgacaaat
     8701 gattacccat attataccct atttagctag atttttcaag gggtttcagt aggtttttgg
     8761 taaatttttt cccatagaaa acttggcatc acattcgaat cacgctatgg tacaaaaaac
     8821 tgaaaaaact attgactgaa aatcattttc aaggtataat aataaacgtt aaggcggtat
     8881 agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt cggttcaaat ccgtctaccg
     8941 ccttctataa cttgatttat caggtttcaa atgaacagaa agcccaattt gaagggcttt
     9001 ttttattttc cctcgaataa atacgtataa ctttaaaaac ttttggagcg agtttgtggc
     9061 agagttcttt ccatggcata attccctttt gaaatcaatt gaaaaaagct tcgtcacgcc
     9121 tggtgacaaa agcctctagt ttattctgtt tcttcttcta tttcgacttc tgtgatttgg
     9181 acttttacct tggtaacacg tccattcttc actttatcat tggttaagat aaactgtttg
     9241 ttttggctga ccaattcata gctgagtttc tcagtcgttg gaatggttcc cactcctgtc
     9301 aaataataac cagcgatggt atcaacgtca tcactttcca gctcaacatc aaagtaatta
     9361 ttgaaatcat tgagggtcat agttccttga acaatgtagg tatcctcgcc aatctgatga
     9421 acatctattg ctgctttgtc cgtttcatca tcaatttcac caacaatttc ctctaagagg
     9481 tcttccaaag tcactaaacc agccatacca ccgtattcat ccagcaagat tgccatttgt
     9541 ctttgggtat ttcgcagttc ttttagcaag tcatccacaa aaatagtttc aggtacaaaa
     9601 agtggatctt gtaaaattct cttccaaaca atattgtcaa aaccgtccac aaagcctgcc
     9661 ttaaggagac tcttggtgtg aatgattcca attacattgt ccttatcccc atcataaacc
     9721 gggatacgag aataattttg ttttaaaata ctttggataa tggcttgact atcatcctga
     9781 atatccacca taaaggcatc cgttcgagga accataacct ctcgtgccat cagttcatcg
     9841 agcgaaaaga caccttgtag catctcaatc tcatcagcat ccaatgtttc ttcactattt
     9901 gtcagcatat aggcaatttc atcacgggtc attttttcat ccgcatcatc gaatgacata
     9961 ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa gccaaacaaa aggactgact
    10021 agttttccga tcccaatgat aaccggcgct gtacgaattg ccaaggcatc ctttagatta
    10081 agagcgattc tcttaggata taattcccca aaaacgatgg aaatataggt caaaaatgcc
    10141 aaggatagaa aagttgccac ggcttgtgct gtttcgccat tcccaagcca agaggcaatc
    10201 acacgtccta gagtatcagt taaactcgcc cctgataaga ttgtaatcag ggtgattcct
    10261 acctgaatgg ttgataaaaa gtggttagga ttttctagta ccttcagcag gcggatgtag
    10321 cgtctgtctc cttcttccgc cttttgttca actcgggcac gattaagaga aaccatggcc
    10381 atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga taaacaataa aacaaattgt
    10441 agcaacaaat tctgactact tgggtcttcc atagttcttc tcctaaaata gtatcttatc
    10501 ctttattata tcacaaaatt taatccaata catattattt ttttcttagc gtaacttcca
    10561 tctctctccc aaaactggaa gttagtctaa gacggatttc cactgatttc acgcgttttt
    10621 ctcatactaa aagctaggtt gtgggaaact ggaagttagt tttagaagtt actatttttt
    10681 cttagtacct attctagccc tgcttaaact agtaaaaaga actcctacat ccataagtga
    10741 cataggagtt taggcttatc ttttactgag ttacagttac ttctccagtt cggtaatcca
    10801 gttgaagtcc cttttgaaca ttgggaacta gaacattgaa ttccaattct ccatccgaag
    10861 acttggcttc aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg
    10921 ttacacggta acggacacgc ttgttttggt ccaaggcttt acgcaccttg ctttcatagt
    10981 agttttgacc agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa
    11041 tgtttttagg attgcttgtt gaggcatcaa aaccatccaa accaccgatt aaggcatagc
    11101 ctaacaaatg acctctatcg actgcatggg tataagagcc ctttagattc ttgacctgat
    11161 gccaacctgg aggagtccaa gaagttgaac cattcccagt ttctttacga ttcttgtact
    11221 gacgagtggc cttagacaag agggcattag ctacggttgg aacagtttcc ttgcccactg
    11281 tctttgtttt attgtcagcg tagggcttac ttgaaacctt ggcatctaga tttgttttat
    11341 taccattgac gataaaagca cctgagccat tccactccag actccccttt atttgactct
    11401 tgactgcgtc tgttaagaca ctctctgcca atgcttgact aggagcttca gacgcttgtt
    11461 ttttctgact aagattggtt ttgggactat taggtgccga ctgcatctgc ttgatataat
    11521 agctccctgt agacaaaagc aataacacta gcagtccgat tagtgtctgt cttgtttttt
    11581 tgttcatatt tctccttatc tttagaaaaa ggctggttct ccagcctaat ttcctgtaaa
    11641 tttatgaatc aattcctgcc attttgctgg agacaggata gcccatggat cttgaccctt
    11701 gcccaagatt ccataaccta ccattagacc gattcctaga gccagagtac ctaaaatcag
    11761 tactatgatg actaaaagta aacgattgat tacgtagctt gatttcttat tcatcttcat
    11821 cgcttgcctc aatccgctga atcttagcac ctagctgcgc caacttctca tggaaaccgt
    11881 agtaacctct atccaagtga accaatttac cgaccacagt ttctccctgt gctaccaaac
    11941 ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga aagaacttct gctccctgca
    12001 aaggctgtcc accaacaata cgagctgtat cacggataat ctcagaatgc aagcccatgc
    12061 ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac tgtctccacc atggttgatt
    12121 cgccttttgc aactgtcatc aaggctgtaa attgagcctg catatctgtt ggaaatcctg
    12181 ggtggggcaa ggttttcaca tgaacagctt ttagattttc tagttgagaa cgaacacgaa
    12241 ttccttcgtc ttcttcaatt acttcaacac ccatttcaag taacttggca atcaagggac
    12301 ggttgtgctc ccagacagcg tctcgaatca agacatcacc accagtcatg gcagcagcta
    12361 ccataaaggt tcctgcttcg atacggtctt ggactacatt gtgagtcgta ccatgaagtt
    12421 tctcaacacc agtaatggtt atagtctctg taccagcacc tttgaccttg gctcccattt
    12481 cattaaggag aatggctaag tcaacaatct caggctcacg cgcagcattc tcaatcactg
    12541 tcaccccatc agccagagtc gctgccatca tcaagttctg cgttgcacca acacttggaa
    12601 agtccatata gatatgagca ccatgcaagc gttctgcctt ggcttcgatg taaccagctg
    12661 tctgactaat cttaaccccc atagcttcca gacctttcaa atgaagatca ataggacggc
    12721 taccaatcgt acaaccacct ggcatggata ccttggcatg acccacacgg gcaaggattg
    12781 gccctaatac aacgatggag gcgcgcatct tgctgacata cttgtaaggg gcttcctcag
    12841 tgatgtcgcc agtagcatcc accttgacaa gatgagcttc ctcatcaaag tcaaccttgg
    12901 cattcaaacc accaactacc tgattcataa taaagacatc cgacaaaatc ggaacattct
    12961 gcaagacggt ctttccttca cttgctagaa tagtcgctgc caacaagggt aagactgcat
    13021 tttttgctcc ctcgatcgtc acgcttccta ccagacgatt atcgccacct tgaaccacaa
    13081 ttttatccat actcgtttcc tttactcttg atttcataat aatcctctaa gcgcttcttg
    13141 ccacaaatga tacaggctaa taaagaaaga actcaggatg tagcctatga caatgctaaa
    13201 aaaggctact aataaacgaa cttttcttgt attctcatct gtcactttta aaaccttctc
    13261 ccatctaaca agatccttta aaaggtaaaa actcacataa ataaagagca tatgactact
    13321 tagagtgaat aataattgaa ccatttgact attataccat cttctctgtt tgtgcgctag
    13381 tttggaaact tcactcaaaa attagggatt gtttttcaag taatcaatcg catcttgtag
    13441 ggttttaacg ggcacgattt tcatatccgt cttgattgtt ttagccgctt ctagggctgt
    13501 ttggtagttg tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa cagggttatc
    13561 aggagcaaag aaaatagcag cacctgccct agccgaagct acaaccttct tatcaatacc
    13621 tccaatgtct cccacattac catcgcggtc aatggtacct gtaccggcaa caatacgacc
    13681 attacgaaga tctgggtgag ctatttgagt atagatagct agactaaaca tgagaccagc
    13741 acttggaccg ccaataccag ctgttgaaaa gctaattggg acattgctga ttacctctgt
    13801 acggtcaatc aagccgattc caattccatt tttgccattt tccaaggtga taatctttcc
    13861 ttctgcagac ttggtttgcc catcctcttc ataggtgacc ttgacggaat cccctaattt
    13921 ttgagaactg acgtaatcaa tcaagtcttt ggaactatca aaggtctgat cattgactgc
    13981 tgtgactgta tcagagatat tgagaatccc tttaaaggtt gaattatccg tcacattcaa
    14041 aacataaact ccaaagtact tgagttcgat atccttacca gctgttttta gtccttgata
    14101 cttggccata ttttgcgatg tttgcatgta gaattgattg attcgcataa attcaacatc
    14161 ggaagaacca cctgtagtct cctgagcact acgaatatct gtaaaaggtg tcaaccaagc
    14221 ataaatcata tgagctaaag tggcatgttg aacaccaacc gtaacgaatt gataggcacc
    14281 agcttcctta tcttctgtgt catttatttt aaggacttgg cgaatatctt ccgaaccacc
    14341 tggaacctct atataataag gcaagggcac tacaaatgcc aagaaagtca caatcaaggc
    14401 cgcaatgacg tataagggcc atctaatctt ttttttcatt tcttatttcc tccaaaatac
    14461 tctcgggaac atagcaggca atatcctgac caaacttcaa aagctctcta acgcctgatg
    14521 aactgatata gagatgttca ggtcgactat gtaaataaat agtctctata tcagaagaca
    14581 gctgatgatt gtagtaatca aaactggctt catattgcaa atccgacgca ttcctcaaac
    14641 cacgcactag acaagtagca cccaatcttt ttgcaacatc gaccaccaat tcatcatgag
    14701 aagccacgac ttcaacattt tccagatgtc ccaaagcctt ttctagcccc cgtttacgat
    14761 tttcgatagg aagaaatcct tgtttgtggg gattaaaaaa aataccgaca tagagcttat
    14821 caaagagtct gctcgcccgt tcaatgatat ccagatgccc atttgtcatc ggatcaaatg
    14881 agcctgtgaa taagccaatc ttatctgaca tagactgtca ccttactaat tccataaatc
    14941 ttttccttcc agatacccag acaggcaatt tcttctggaa gttcaacggc cttatccgtc
    15001 tcgcacacaa ccataacatc ttcagaaaaa agctctctct cagccatttt ttcaatatct
    15061 gctacgattt gttccttggt atagggaggg tctaagaaaa cgaggtcaaa ttccccagat
    15121 acctgttcca atgccctttc tgcatccatc ttgaggagtt gaaattttcc aatttccttg
    15181 gttatctgga tattttcagc cacgatggtc tgagccttac ggtctcgctc caccaaaaca
    15241 gcactggaca tgccacgcga tactgcttcg atagataaac caccactacc tgcataaagg
    15301 tccaagactc gtcccccttc aaagtaggga ccaatcatgt taaaaatggc tcccctaacc
    15361 ttatccgaag taggtcttgt cgtcttgcct tctagtgtct tgaggggacg tcccccatag
    15421 attcctgata cgattttcat actgtttatt ataccaaatt atagacaaaa agagaaagaa
    15481 aaccgaacct tgcggttcga ttctctacaa aatattttcg taagtatcgc ggacttcttg
    15541 aggccaaaca cttgtttgca cttctccgat gtgtctcttg cgaagtagga acatggccat
    15601 acgagattgt ccaattcctc caccgattgt caatgggaat agaccattca acaaagactt
    15661 gtgccattcc aattccaagc ggtcttcatc acctgtaatt tccacctgac gtctaagagt
    15721 ttcttcatct acacgaattc ccatagaaga caactcaaag gctccaccta aagactcatt
    15781 ccagacaaga atatcaccat ttagaccctt gtagccattc tcagactcgc ttgtccagtc
    15841 atcatagtct ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc caccgatacc
    15901 aatcaaaaag acggctccaa attctttaca aatcgcattt tcacgttctt tcggtgtcaa
    15961 gtctgggtag cgttctacca attcttctgt atggataaag gtgatttgtt ttggcaagat
    16021 agactcgatg tcatagcggg cttcaacagc tagctcagtc aggcgaatag ccttataaat
    16081 cttctcaact gtttctttta gataaacgat gttacgctta ccatttggga taaccttctc
    16141 ccagtcccac tggtcaacat aaacagagtg ggttgcatcc aaggaatcct catctggacg
    16201 aagggctttc atgtggacaa agagaccctc tccttcacca aagccaaaac gagccaaggt
    16261 gtggcgtttc catttagcaa gtgagtgcac cacttcataa gtagcatcag ggatttggag
    16321 aaccttgacc gatactggat tttccacacc agacaggttg tcctgcattc cgtcaccgac
    16381 cttactcaag ataggacctt gaacttcgac aacttctagc ttatctttca aatactgggt
    16441 aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt tcttcataga
    16501 caactcctca aaaatttaat aaacgtatta tacacctatt tccaagaaaa gaaaagagaa
    16561 aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga
    16621 ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc
    16681 attgacacca cccaacctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc
    16741 ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata
    16801 taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg
    16861 agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa gataccaact
    16921 gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga
    16981 gtatagaaag ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat
    17041 actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc
    17101 aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac
    17161 tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga
    17221 ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata
    17281 gtgtgattca tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag
    17341 ttaaaattag cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc
    17401 ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact
    17461 aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct
    17521 gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt
    17581 ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg
    17641 catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc
    17701 tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac
    17761 atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt cttctctttg
    17821 aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc
    17881 tgacacccag acagtttgcg aaaaagtagc taactgatct cgataatttt ctagggtaaa
    17941 gattttctca atcgtcactc cagcttgaac agcttcttca aacaagtgcc agccttcaat
    18001 caaataggct gacttgcggt attttttttg gtgtaatttc ttggtatttt ttaccacaga
    18061 attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt
    18121 atgcaaaagg ttagaatgat tgcccaaggt agggtacagg gagtcggctt tcgttggggt
    18181 gtttacagct tggcccttga aatcggtggc atcacaggtc gggtatggaa taacgacgat
    18241 ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa
    18301 gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc
    18361 aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat
    18421 tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga
    18481 aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg
    18541 gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg
    18601 gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg
    18661 tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc
    18721 aatcatggaa ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc
    18781 cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag
    18841 ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc
    18901 ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag
    18961 gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg
    19021 cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacggg gtagaagatg
    19081 aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct
    19141 tctccctctt ctcaccagcc agtgttacac tttactgggt tgtcggtggt ttcatgatga
    19201 ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg
    19261 aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag
    19321 acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg
    19381 ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg
    19441 caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat
    19501 aatcttgata actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg
    19561 gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca
    19621 tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac
    19681 caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc
    19741 agacaggttt tccaatatct gatagatact gggcacaagc caagatattt ttattagttt
    19801 gtctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt
    19861 cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa
    19921 gagcacaggt atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa
    19981 tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc
    20041 cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg
    20101 acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac
    20161 agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg
    20221 tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac
    20281 cttccttgaa aacgttttat agttttatta tatcatgact tgaaggaaaa acaagatttt
    20341 tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta
    20401 ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg
    20461 gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt
    20521 atactggtag cccattgaaa atccgtgggc acctgtatca tgaatgacca gcaaatcacc
    20581 gatttctgta tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga
    20641 accaaccaca tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg
    20701 gtaagctccg tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata
    20761 ggtacggtag gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag
    20821 cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac
    20881 ttcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc
    20941 tggacgataa ttaacaccaa taccgccaga aagattgata aagtctagcg aaatgcccaa
    21001 cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag
    21061 atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc
    21121 cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc
    21181 aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga
    21241 gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa
    21301 gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga
    21361 agagaacata atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata
    21421 actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg
    21481 agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac
    21541 ggctcttgcc ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc
    21601 ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct
    21661 attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt
    21721 atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt
    21781 agttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc
    21841 cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc
    21901 gttgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt
    21961 aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata
    22021 gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga
    22081 gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat
    22141 aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa
    22201 gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc
    22261 actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat
    22321 agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc
    22381 aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga
    22441 ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat taatcaaata
    22501 gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat
    22561 ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg
    22621 ttttgagatt gtcgatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac
    22681 aaagcgatac taccctagtt tgaagatatt ttcgaagagt attcattttt gtcttttact
    22741 tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc
    22801 ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta
    22861 ttggtcatct ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca
    22921 tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg gactggactt
    22981 ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc
    23041 ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg
    23101 atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg
    23161 atgaccttag ccaagtcgtg caacataatc cccgcataga gcagactctt attgagctga
    23221 ggataaactt cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg ataagccaac
    23281 cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca
    23341 tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc
    23401 atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg
    23461 gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg
    23521 gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc
    23581 tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg
    23641 aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt
    23701 aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac taatcttcat attcttcctc
    23761 attttcttga aaatggagta gatcaagcgc aggctcgcct tctgacaact caatgtgacg
    23821 gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc
    23881 atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt
    23941 gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa
    24001 accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa caataatctg
    24061 ttcttcccgt ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc
    24121 ttctgtcgga acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt
    24181 cctaatatcc ctagcaaaac gcttgacact tgctaggagt gacttacgac agcgttcgat
    24241 ttcatccttg tcacctactt cataggcttc ttctaagcgg taataatctg ccagtggaaa
    24301 cttagagtca attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc
    24361 atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg
    24421 tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt
    24481 ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc
    24541 aagaccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg
    24601 tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg
    24661 ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag
    24721 attatctgtc atttcttgac ggacttgggt caggccttgg tgcaattcaa tccgcacttc
    24781 ttgcaaacgg tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct
    24841 ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct
    24901 cttacttaag tgtttctcct gcctatcctg tctttgccaa atcagaaaga gaccagctag
    24961 gttggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca
    25021 gtacgaccac ataaccatct gggcaagtca ccgacacttc cctatctata tattcgttag
    25081 aagcgtacac ttttttaaag aaaaaattct cctctgtcaa ctcatactta gctccaagaa
    25141 tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt
    25201 ctagctgact ggtcccttct gaacaatagg caatcaaatt ttgcccatcc tcaatttcta
    25261 tttgacgcat atagggtgcc aacttaggat tgctaggtag aaagacattg gccaacatat
    25321 ggtcaatacg gccacccaag gcaccgaaaa tagtgacctc agcctgagga ttttgttcaa
    25381 agatggttaa gagagccaat tccagatctg tatcatcctt ttctggtcgg gcttggacaa
    25441 aatgctgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatccc
    25501 caactgctag agcaagaagc aagtcttctt ccaagaccca gagcgagcct cgatccaccc
    25561 caacaaaagc atcaaaatct gtccgataat gaccgcggtc tccgcctgca aaaacggcaa
    25621 ccctagtcca gttgttttct gagagtttgt actcgctcat tgacatctcc cttaaagaca
    25681 taggaacctg ctacaaaaac ggtcgcacca gcttctttag cttgggcaat agtttggtca
    25741 tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc
    25801 aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta
    25861 accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat
    25921 gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg
    25981 ccatgaatat gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca
    26041 aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta
    26101 ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga
    26161 ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca
    26221 cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata
    26281 ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc tacgattttc
    26341 aatttcacta aggaattgca ggtaattgtc aaaacggaag gttgcaataa caccctcttc
    26401 aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca
    26461 atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac
    26521 ttcatagtcc aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta
    26581 aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt
    26641 ttcaagattg aggtctggtg cgattttatt gagaagagtt gacttcccaa cacctgtctg
    26701 ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac
    26761 aaagtcatag ccgatgtcac cataggtctg ctggtaaaaa tccagttctc ccctatcttc
    26821 caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac
    26881 caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac
    26941 agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt
    27001 gaggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg
    27061 ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact
    27121 ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt
    27181 gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca
    27241 cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag
    27301 tcttaccaaa gtaacctgtc aagttattcc acaaggtctt gcggcgatgg gtaaaactag
    27361 ccttggaaac cttaaagaaa aagttctcat cttctactgc tacggctggc tctggacgac
    27421 gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca
    27481 cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag
    27541 ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa
    27601 actcactaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt
    27661 aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt
    27721 gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca aaatcacgca
    27781 gggtatctac caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg
    27841 cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg atgacattga
    27901 cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcagga
    27961 aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca
    28021 cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac
    28081 acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag
    28141 aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca
    28201 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgtcgtactc aagtacagcc
    28261 tgcggctagc ttcctagttt gctctttgat tttcattgag tatcaaaaaa atcagcttct
    28321 tgataacttc tattttcggg tagggtcaaa tccacatcct cctccacatc atccactgtc
    28381 agttcaaccg tttgaggtaa atttttcaaa cgataatgct tttgccttta cccttcaata
    28441 ctagcaaaat caagcaaata gccatgcact aggatttgaa ccaaaaggag atgattggtc
    28501 atatttttat cttctaaacc acctctggca ctaggataat cagataccct gcgaatacgg
    28561 attttttcac acatgagcaa gtttcctcat atcaatgatt tcatcagcct tattccagac
    28621 taggggatta tgggtcgcaa tgatgataat tcgattttca tctttcaaat ccaccaagag
    28681 attcataacc tcctctgaat tttcaggatc aagagctgct gttggttcat ctgccaaaat
    28741 caagggtgga tttttcaaaa tagtttttgc aagggcaact cgttgggcct ctcccccaga
    28801 taaagtatag attttttgtt ctaaatccaa ataccctaga ttaacttttt ctaaagcccc
    28861 cacttgcctt tccaaacgtt ctacttttga gattttctga ccaacaaaac ccaaatccaa
    28921 attttctttg attgattggt tttctaagag gccgaaattt tgaaagagat agcccatctg
    28981 gtctcgaaaa tactcacgag taggaatggt ttttaaatct ttcccctgat agagaaccct
    29041 tccaccatct atcttttcta gctttcccaa gatattcagc agcgtcgtct ttccgcttcc
    29101 actctttccg attaaggcat aaaccttgcc cttctccagc ttgagattca aaccagagaa
    29161 aatcgcgcgg tcattaaatt tcttttccaa tccttgaata tcaatcatct tattttcctt
    29221 tcaatactgc catgctacca gcttcttctt ttttgtcctg ccttactaaa atcaagaggg
    29281 cgttaagcgt aaacaaagct acaactagag cgctaatcaa accatctctt gtcaaaatac
    29341 tagataggac taggccaagc aagagaactc ctccttgcgc cagtaaatac ttgccatgaa
    29401 gttcatagat tgtcatacca gcaagacgtt taatcataag ctcccgtctg aactgctcaa
    29461 aatagagaag attcatggaa tcaaataaca agatagccgt agacagggtc aaaatcgtcc
    29521 caataaggag agagtaaaac tccacccgtt tgtcatttag taccttggca aaaaatagct
    29581 ggctttttac caagtaagaa accttgtgat acagaccttg ctcttttaga gctgtgatgc
    29641 tgtctccata tcgatctagt ttcaaggcac tattagccgt agttccccac aacatccctg
    29701 caacaggtct tgttccagtc gcttgcggcg ttagaactac aataatcgga tcttttaggt
    29761 actggcgtgt tgtcttgtac ccatcattat agaggaaacg ttcctgtcct gtttctgtaa
    29821 aagctagcct tacctgtggg aggtagtgtt tctgactcgt cacttctaca ctttcagatg
    29881 aaaagttttg caggtaatct gtaaacaatc cttggtagta gacagactgc tctcgcaagc
    29941 tctcaggcaa gatcagccca aactctccct cagacaagtt ttgcatcttg tccataaact
    30001 ctgaagaaac ggtaatcttt tcttctatca gatagcgtgg tgagacatag ataacattcc
    30061 ctgacggtgt gtagtcactg agacgattgc catctaggtc cacttctgct ccatctgaga
    30121 aattgtcaac attgctcata atataaaaag agtctgtatt ggctaaccgt tcttcagtaa
    30181 atgtctgcca ctcacgatta tccttacgcg ttccttcttc atcggcaaat gcactagacc
    30241 aaccaaagga tagacggtaa cggtctgagg actggctcca tttattgcta gctctctcca
    30301 tttcctgcat ttcacggtag tggggtagga gagctgtcgc actcgatccg accaccaata
    30361 cagctaagag ttgccccacc atcatcaatg tcatcatacg tttgagaggg agtttccctt
    30421 tcaatagatc caccagacta ttttcctgta aaccaagtag atagacgaca cttagtaagg
    30481 tagaaatccc tgccaaggtc aatccataaa gtagaagagc aatgatgacc agttgcaccg
    30541 ttgccataaa caaggcacct tgataccaga gaatccccaa tcccaaaaga ctggatacca
    30601 gcactgagca gataagctgt ctcacatctt ctaacactgg tctgagagca actccaaaca
    30661 agctctcacc agctattaag cgaatccctg cctgacgaag ggatttgatc cgataaatca
    30721 gggtcagact cataaaggtc agcagaaaaa tagctaaact cagtagcacc ataggggtgg
    30781 ccgtcaatag taagactatc gaaaatggat cttctccatt cgaaacaaag ccttgataac
    30841 caagctcttt caaggtggtc tgtaagctca ctccatccaa acttcctgac acaatcaagt
    30901 aagaccctaa taaatcactc gtttctgcac tctccttgga ggaaatggtc agaccttctg
    30961 gaagctttcc ctcaccataa gtggcatagg taaagcgtgt ttctccagct tcatttggct
    31021 caacgattcg acgagcaatg agactattgt gctctaccgc caagtgactc aaagcctctg
    31081 tcacctcttc ccgactagct actggttgat ttatcatcat tcctgtcaca tcaacagaag
    31141 gatagttacc aaataaaatc tcttctcgat ggtcaacgga agttatcacc atataaagcg
    31201 ataccaatac cattgaaatc aaaataaata aacgtttcat catttcctcc aaaaagttac
    31261 ttggtcactt agtgagaagg tgaccaagta aagctaaaca atagggctat accattctaa
    31321 acattatagt agaatgcaac tttctctccc caagaagtac gaatccatgc acgagaagtc
    31381 cctccagcac cagcatatcc cttgtcagat gaaccagttt ttctgctaac aactgttgaa
    31441 ctatggtatt ttgaagggtg atagtagttt gagtaagcac caccgttacc tgaaccataa
    31501 gtccaaacac caccttctgg gtattgaacg gctgcagagg caactgctac acttccacct
    31561 aatgttgctg caatgctcgc tacaagagct aattttttaa ctgtttgttt catattgata
    31621 ctcctctatt tttgattaca agattgttga gttacttgct cctctttcca ttatcaacgt
    31681 tgatactatt atattaccaa atgatattct aaaattattt gtttttctct aaattgtcaa
    31741 aatagcaccc tgaaatgaac ttttatagtc attatactcc atctttatca cactatcaag
    31801 gacatcaatg tccttaaaat ctaactattt catattattt ttagcttata tctaaaaaaa
    31861 cagttctaaa gacgaacttt agaactgttt tgatacgagg acaaggacat ttttgtcact
    31921 gattcactat gtttataaat attttttgac atcctcttgc cattcctctg tcaatttctt
    31981 tactagaaat ccatctccaa ttagcttcgc aaatgtttta gaagactgat aaaatgattc
    32041 agctaaacta aaatctcttt ctactcttaa tgcttgcttc cacaaaaaca taaatacaag
    32101 aggtttcttt tgataatctt gagttttatc cataatttct tgtaaacacg atagataatc
    32161 attaaaacaa tcagttactc ctaccttttc aagacaacac attcctgaaa taagagtatc
    32221 tctaattata aagtaattct ctatttgagt taccttcttc tgttccaaaa gaaagagcat
    32281 tagcttttcg atttgattta taaatttggc aagatctttt ctaatgagca tttgataaaa
    32341 aaacaaacga atcaacaaca tatcatttat tgaataagct tctttttcta taatctgagg
    32401 catatgttcc tcaagtatta actctgcata ttcaggcctt ctagttctag aagtatccaa
    32461 acacgcctgc aatacttcac atgctaattg ttcttcttta ggaagattat caaagtatgt
    32521 tttataaatc tcttccaaac acgcttcctt cttatcgtac tcctcttctt taccatagat
    32581 tggttcacgt aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc
    32641 cggcataagg ctataaactg gaactcctag ccggcgagca atataggcta acttgggcaa
    32701 actcggttgc gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc
    32761 atctccacaa aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg
    32821 accaattaac atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa
    32881 aaattgtaac ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc
    32941 aaagtaaccc caaacaactc taggcgtttg aggagttgct tgccgttaga atagccgatt
    33001 cggagagtct ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca
    33061 aggcgaatca aatcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc
    33121 acctgagcta gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc
    33181 cccttggtct tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt
    33241 ggaatggccg tcataatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag
    33301 acaatgactc catgacgttg gtgtagacgc tgaatccgct ctatgtcctg gtcattgatg
    33361 gcagaacctc gagtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca
    33421 tcacgacctt caaccacgat aacttgggaa attctctctt tcattacttg ctgtccaatc
    33481 caaaaatgcg ttctgcattt gcagtcgttg ctaccgccag ctcttctgtc gtcataccac
    33541 gcaagtcagc gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac
    33601 gcttgggtac aggtgctaag taaggcgcat ctgtttctac caacatcttg tccaaaggta
    33661 actctttagc tgcttcttgg aggtcagttg ccttcttgaa ggtcaccact cctgagaagg
    33721 aaatggtcat accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat
    33781 gcatgatacc accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca
    33841 gcgcatcacg ggtatggaca acaaaaggca aatccaagtc cttagatagc cgaatctgac
    33901 ggcgaaaaac ctgctcctgc acctctttgg gcgctgtcat ccaatggtaa tctaagccaa
    33961 tttcacctaa agccacaacc ttgggatgtt ttaacttatc caacaagtaa gcctcaactt
    34021 cctctgtata agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat
    34081 actcatctac caactccaag gcacgctcaa tcatcggttt atcaaaacca acaatattca
    34141 tctgtatcac acccatctca gcagccaagg caatttcttc tgcctcacga cctgcaaatt
    34201 cttctacatt caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc
    34261 ttctattata ccaaaaaaga ggaggggcac ctaatttttc ggtttcccct cctctcttca
    34321 atagagagct attctgctat cttttctatc cgatattgcc catctcctat tccacagtta
    34381 gagacagaag agattggcta cattgataga atattcctat tcagctaaag tatgtgatta
    34441 tcttgggttc tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt
    34501 ataatctaac tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc
    34561 tttcttccta gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct
    34621 gcacttgatg ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca
    34681 tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc agcattagga
    34741 gccactagtc tcttaggaac tgtaaccatg gcaatggctt gcactccaat cgtttctgct
    34801 tccttcacat cttccatagt tttcgcattt tcaatctctt tgagagctgc ttgtttttct
    34861 gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc gcctttgatt
    34921 tcatcctgct tgtccttggc tgctttttca atggcatttt tagctgattc tttttcagta
    34981 gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg agctgatcca
    35041 cccgcctggc taccaccgcc ttcattcgca ttagcatctg agcttccaat attgcctccc
    35101 ttatctccac ctggtgtagt ttctagctta tactctggtg taacttcttg agttacagat
    35161 tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac tgaaccatct
    35221 gggaatgtga ttgttgctgt accatctcca gctacattga ttgtcgctcc gtctaatgct
    35281 gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa atgagttata
    35341 tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc agtcggttta
    35401 gtgctatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat tgtaatagct
    35461 gaaccatctt taaagacgat tgttgctgta ccatctccac ctacttcaac tttatagtaa
    35521 aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    35581 agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc gaatccattt
    35641 gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc tactgatttt
    35701 tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac gacgagctgc
    35761 caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt tgcgcgcacg
    35821 acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat agattttgta
    35881 ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt ctatctgatt
    35941 ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat gcaagcccta
    36001 tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta actcatcaac
    36061 acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc ctcgaccatg
    36121 aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat catcatcgat
    36181 acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg gtttaacggc
    36241 agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct cgtagattcg
    36301 tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag tttgtacgac
    36361 ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga gcccttcgat
    36421 atagccctta acatgagtct tagggccaga caagaccatc caacccacac ggaaacctgc
    36481 tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg gtgccaagct
    36541 cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt catccgcaaa
    36601 gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt ccttaggata
    36661 aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat tggaagtgat
    36721 ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac agatatagtg
    36781 aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt ctggcattgg
    36841 cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa tcaactcact
    36901 gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct tcagctggca
    36961 atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat agccttcact
    37021 atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa agccaaattc
    37081 tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca tccgcatggc
    37141 ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac tagacttgtt
    37201 atattctttc atcttgtttc ctcaattcat caggatagta acattatacc actagaaaga
    37261 gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa accttgctaa
    37321 aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca cataccaaaa
    37381 gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa catgaggaaa
    37441 agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag aaataagatt
    37501 agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag aagcggtacc
    37561 agactctcta attgacagat catgatcact tttaccaaga ctgaaactag gataattcca
    37621 taataaagga aatttgattt ttgaaaagag tttttcatca ttctcctttc ctcctatcct
    37681 ttcttttatt ttatcatata tttatataga gtttaagccc taatattctt ttgaaaaata
    37741 ctttttttgc tttacttcta tagtgaaaag gtttacaatt atagtaagaa aatttcagga
    37801 ggtttcatta tggcacaacg ttaccaaaat atcatggtcg caatcgatgg ttctaaggaa
    37861 gcggacttgg cttttgtcaa gggagttcat tctgctctac gaaacgacgc taaactcacc
    37921 atcgcacatg tcattgacac acgcgctctc caaagcgtat ccacctttga tgctgaagtt
    37981 tacgaagaac tccaagtcga cgctgaaagt ctgatgaaag agtacgaaaa acgtgctaaa
    38041 gatgctgggg tagcagatgt tcatatcgtc attgaaatgg gaaatccaaa gaccctgcta
    38101 gcacgtacta ttccagatgc cgaggaagtg gacctcatcc tcgtgggcgc aactggtctc
    38161 aacgcctttg aacgcctctt ggtcggctct tcatctgaat acatactccg ccatgctaag
    38221 gtcgatttgc tggttgtgag agaacaagaa aaaaccttat aatcacaaag aaaaggagcc
    38281 cctagctcct ttttgtttac gatttatttc tctctttatg gcgttcgtaa gccttgagct
    38341 ggcgatgcag ttccttttta atagcaggtt ctggagcata tttttcttcc caattatctg
    38401 gttttaagat tttatgggtc actggatcaa aatgagcctt gccatctgga aaaattttcc
    38461 ccatattggc ctgatggaca atatcaaaaa tacgttctgg gtccaccccc atcaagacaa
    38521 aactgccgta ggtgaagtaa agcgtgtcaa tcaaggcatc cacttgccct atcaaatctt
    38581 gctgagcagg tgtcttcttg gctactttac ctgctgcctt atcaagggcc tgatgaagtt
    38641 gcgatacagc ttgaccaaaa tcttcttcag aaggactggc tgctcgaaca aactccacca
    38701 attcttctat tttaaaacca gccctatggg ttgcaccctc taaatcccaa gctcgaggtt
    38761 cttcttgggt tcgttcatcc atcatgtggt ggaaggtctt gaccttattg aaatgatagt
    38821 cacggctgac aaagactttt tctgaagaca aaacaccaaa atgttccaag gccttgtgga
    38881 tcccatcttg ttgattgcta gtggtaatgt gcttggcagc ttccttgaca ctgctactac
    38941 catttcccat agcgaccgac ataccgacgc cagccagcat ttcaaggtca ttatctgagt
    39001 caccaaaagc catgacttgg ttgaggtcaa agccatattc tttcccaact cggcgaatgc
    39061 cttctaattt agaatttccc tgattgatga catccgatgc aaaaggattg ctacgtgtca
    39121 atttcaagtc ttcaaaatca gctgccgcct tctcagattc ttctggtgtc atcagcatca
    39181 aaacttggta gataggctga ttcatcaggt gaagcaggtc ctcttccttt tggggaacaa
    39241 ccttgctgac catgcgatta aaagactgac tcaccgtccg agttaaaaca gagggaacga
    39301 agcgactaat tcgttgggaa aaagaaccca gaccaaagga catgatttta gaacccaaca
    39361 tggcatcctt ggtccctaga gcaatctccg tgccctcttt tttagcatag ctaattagat
    39421 ggcgcaaatg taacttggaa atagggctcg tgaacaagac tctgtcttta ctaaagatat
    39481 actggccatt ataggttacc gcaaaatcca gatccaaatc gtccatcaat tccttaacaa
    39541 aaaaaggtcc tcgccctgtc gctacgccaa ctagtacccc ttgttctttg acaatcttaa
    39601 tcgcgtcctt agtggatttc aaaacactct tgcgattgtt gaccaaggtt ccatcgatat
    39661 caaaaaaaac agctttgact tccatcctat tccaatctcc ccttttgtga tacaatgatt
    39721 ataccacatt tcagaaagag tgagtaaatc atgcctaaga aaatccttgt tttacatacg
    39781 ggtggaacta tttccatgca ggccgatgct tctggcgctg ttgtgacgag ttcagataat
    39841 cccatgaacc atgtgtccaa cccacttgaa ggaatccaag tccacacctt ggactttttt
    39901 aaccttccaa gtccccatat caaacccaaa catatgctgg tcctctacca gaaaattaaa
    39961 gaggaagcag ataactacga tggagtggtg atcacacacg gaaccgatac tttagaggaa
    40021 acagcctatt tccttgatac catggaagtt ccccatatgc ctatcgttct aacaggagcc
    40081 atgcgtagct ccaatgagct cggtagtgat ggtgtttata attacctaag tgctttacga
    40141 gtggccagcg atgacagggc tgctgacaaa ggagttttgg tcgttatgaa cgatgaaatc
    40201 cacgctgcca agtatgtcac caaaacacat acgactaatg tcagcacctt ccagactcca
    40261 acacatggcc ccctcggtct caccatgaaa caggaaatcc tctacttcaa aacagctgaa
    40321 cctcgtgttc gctttgacct tgatcacata caaggtttag tccctatcat ctcggcttat
    40381 gctggtatga cagatgagct gattgatatg ctggatttag aacacttgga cggtttgatt
    40441 atccaagcct tcggagctgg taatattccc aaagaaacgg ctcaaaaatt agaaagcctt
    40501 ctgcaaaaag gaattccagt cgctctggta tcacgatgct ttaacggtat tgccgagcct
    40561 gtttatgcct accagggtgg gggcgtacag ttgcaaaaag caggcgtttt ctttgttaaa
    40621 gaactcaacg cccaaaaagc tcgcttgaaa ctcctcatcg ccctcaatgc cggactaaca
    40681 ggacaggctt tgaaagacta tatggaaggc taatactctt cgaaaatctc tgcaaaccac
    40741 gtcagcgtcg ccttaccgta tgtatggtta ctgacttcgt cagttctatc tacaacctca
    40801 aaaacatgtt ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgtgttgcg
    40861 cagcctttaa ccagccgcct agtccgctct atggtattca ttaagtcaac atctcttgtt
    40921 taagagcaca aaatcaggaa atcttctcga ttccctgatt ttttctattt acgttttcgt
    40981 gttgagctac gttctgtcaa accatgaggt aagagaactt cacgttcttc caactcttcc
    41041 ttatgcataa tcttggtcaa catacgcata ctaatggcac caaggtcata aagaggttgg
    41101 gcaatcgttg tcaagtttgg acgggtaaag cgtgagattt gtgaatcatc actagtaata
    41161 atttcaaaat cttctggcac agaaacaccc ttatcagcca aaccgttcaa gactcctgct
    41221 gccaactcat cacctgtcac aactgctgca gttgcatttg atgaaatcaa acgctctgct
    41281 aaggcgtaac catcatcata gctatattta gattcaaata ccaaaccctc actataagtg
    41341 attcctgctt ttttcaaggt ttccttgtag ccaactaaac gaaccttacc attgatgtca
    41401 tccactagcg gaccgctaac gaaagcaata cgctcatttt ctttagcaag gtaactcact
    41461 gcatcaattg ttgcttgctt atagtcaata ttgacacttg gcaactggtg ctcaacatcg
    41521 acagttcctg cgagaacaat cggagtacgt gaacgcgaaa attctgagcg aattttatct
    41581 gtcaagtgat aacccatata gataatgcca tctacctgct ttgaaaagag ggtattgaca
    41641 acagaaactt ctttctcgtt atcttcatcg ctattagcta ggacaatatt gtacttgtac
    41701 atttctgcaa tatcatcaat ccccttagcc aaactcgaaa aataaccatt ggtaatattt
    41761 ggaatcacga caccgacagt ggttgtcttt ttacttgcaa gaccacgcgc aactgcattt
    41821 ggacgataat ccaaacgatc aattacctct agcacttttt tacgggtatt ctcttttaca
    41881 tttttattgc cattgaccac acggctgacc gtcgccatgg aaacacctgc ttcacgagcg
    41941 acatcataaa tggttactgt atcatctgca ttcattcctt ttcctgtcct ttctatctca
    42001 cacattcttt tacaagtaga ggtactgatt gaagctctat atctacttac aaaagtgaag
    42061 atgtgaaaat ttcgttttca tatttctact tattccattc tatcactaat tgtaaacact
    42121 ttcaagtgtt ttttgaagat tgattgaaaa aatttcatag aaaacctagg tttagctcct
    42181 tgctaccacc ttagactaaa caaaaaggag gaaactaagc cctcctaaag ttatagtaaa
    42241 atgaaataag aacaggataa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    42301 gaagtagagg tgtactattc tagtttccat ctactatagg tattgttcca ttcactaccg
    42361 tcaattttag cacatagtct tcatgaaaat attatatcat cataaccaac cagattcttt
    42421 tgcgatatta gctgcctctg ttcgattacc agcatccagt tttgaaagaa tattggtgac
    42481 atagtttcga atagttccgt ttgagaggta aagctgatct gcgatttctt ggttggataa
    42541 gccccgggcg attcccttta agacagcaat ctcttgttct gtcaacggat tgggacgggt
    42601 catcaccact tccatcaatt caggcgaata ctccttgcgt ccttcgagga cggtgtgcaa
    42661 ggtttgcatg aggtctgcaa tgcttcgttc ctttaataca taagcatcca ctccagcctt
    42721 gaccgcacgt tcaaaatacc cagcacgctt gaaggtcgtc accacagcca cctttgtttc
    42781 aagcctttct gatcgtatcc actccaagac ttcaagacct gtcttaacag gcatttctac
    42841 gtcaaggatg gcgatatcta cagactcctt ttctaatagt tggattgctt cttgcccatt
    42901 cttggcttga aggacagact ccacatctgg ttgaagcgtg agcaattgac acatggcatc
    42961 tcgcaacata ctttgatctt ctgcgactaa tactttcatc ttagtttctc tccttataag
    43021 gtagtcgaac ttgcacttcc gttggatgtt tctgactgat tacacttact tctcctgaaa
    43081 atggaaaaac acgatctcgg actgtatgga gctcatctcc ttttagaaaa gcaaagccgc
    43141 agccatcatc acttactgtt aaaatgagtt ccttctctgt ccgttctaat tttaagtaag
    43201 ctttagacgc tttggcatgt ttgatgatat tggtcaccaa ctcaagcaaa atcatagaag
    43261 ccattgaatc caattcttga gtaaggctag cagtatctag ttggttatct gtttccacct
    43321 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    43381 acttaagatt ttccacaatg gttcgaactt cacacattga ttctttgcta atttgctgta
    43441 tttctcttaa ttccttttcc acttgtggat aagcctgcat ttgaaatagc tgcaaggcta
    43501 gatctgtctt gacactaagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    43561 cgatacgatt gcgctcattt tctgctagca atagatttat ctgggtattt tgcttgacct
    43621 gagcttcttt caaatcctcg acaaggcgaa ttcgaaccga gcccaaagtc atcaaatcga
    43681 caaaagtaag aattacaagc atatagacta gaaactcaac ttcgattctc tgaaaaatca
    43741 aaagtcgccc cacaacaagg acttgagcaa ggagaaatgt ccatacatgt aaagacttta
    43801 aactacgtac gccaaaatga taaattaaga gattggaaag gaaaaagaaa aaccagatat
    43861 aattcccagc aacaaaggcg gtattcccag ctacatagac cagcatgagc ccccagaaaa
    43921 gccaagatag gcgctggttc ttagttatta aaacacccaa atacgtcact acaaatagaa
    43981 tatcaaccaa taaatgccaa gcaggaagct ccccaatcac tacaggtagg atgggaaaaa
    44041 gcataaaaat caaactggtc caaaacatat agtgtatgct tttcagtctt tcaagcatta
    44101 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    44161 aagtaaataa actgtggctg atagattgat gtcaccctcg tttaagaagg tcttgagcaa
    44221 ctccatcaat tgataggtcg ggagacactt accaactgct tgcatccagt ctggaaataa
    44281 agaaatgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    44341 aacagacatc agctgactag ttggtaagag agtcaaggtc aagccaagtg ctacaaaagc
    44401 aatactcccc acaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    44461 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    44521 catacttgtt atctttgata gataatattc taccatattt acagggctat gacgcaatgt
    44581 tttctgccag ttgttcatct tatcggtatg taaaacagct ggaaatgaga ggatagttgt
    44641 cgacatcatg gaaaaggcag tcatggagat gaggtaatca cgcataaaat tcgcgagttc
    44701 acctggtgtg tcctgataga taccagaaaa aaataaatag aaagccgtcg gcatccctac
    44761 cgacaataga taatagatta attgtcgttt ggtcaataaa aattctatct tactaagtgc
    44821 tatccatcgt ttcatcttag ttatctccct tctgcgtctc ttcaaagatt gtattcaaca
    44881 aactacgatt attaacttcg atttcttgca tcctacatcc tgcttgggct aatagttccc
    44941 agaaagcatc tgcttctcga gtgactactt gtaaagaatc ttgctttagg gtccagtttt
    45001 caaccaaatt tgactgctct acgacttcct tgtaagctat aggaaggata aagtgctttt
    45061 ctatttcctc gctacgcata gctagaggcg tcgtatctcg aatcaactct cccttattta
    45121 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    45181 tggtaactcc ctgcgctttt agatcctgaa caatttccca aaaacgttgg cgggttgagg
    45241 tatccatggc cgcagttggc tcatctaaaa agacaagttt tggtcggcca atcaaggtca
    45301 agacaaaaga gaaaagacgc ttttgcccac ctgacaattt ttctgccaat tgctctttct
    45361 gttgcttgtc aaactgcaac agttgatcga tttcctggtt gctcaaggga tttggataaa
    45421 tgctttgaaa gaaagcaacc aactctttga cctttaattt ctgaacgatg acattttctt
    45481 gaggcagata acctctaata tagtctaact gagaactcgt cactgacaag ccttggatgg
    45541 atacttgacc gcttgtgacc agtttatctc caagcagaca gtccaagagt gtggtcttcc
    45601 cagcaccatt tggcccaatc aaggcgacgc attcaccttc agctacctca aaggaaatat
    45661 ccttcaaaat agcctttccc ttgatgtttt tatgtaatcc ttgaacctta atcatgtcca
    45721 tgatattctc ctttcaacca ctccattccc ataggaaagg cgataaaaat cataaatcct
    45781 agtccccagg caccacggat gaattggcga agcaaggctt gatcaaacca acctgtaaac
    45841 atttctacca accataccac tagtgatagt ccaataaaaa gatagagaaa cgcttttttc
    45901 atttttcaaa ctcctttttc acatctgaga ctaatttcaa accttctcgg ataagccagg
    45961 acatcattcc aaatcctgca aatagctccc aaggaaaatg atagaaatct tcatccaatc
    46021 ctgagaacat gagataagtc atgactcctg ctgctactaa actcattgcg acaatcattt
    46081 tatttttcat ctcttcttcc tccgtttcat acttcaatta tagacttttg aagttggcgg
    46141 agctagatgc ttctgtcact agaaaatatg acaaatgtca taaaaattct gtacaaaaca
    46201 agcaagatac actatataat aaaacacaag tagaaaaaat ctaaggcagc tttcaaaaga
    46261 gatatcaaac ccaattcaca ccataatgta aactaatact tatttaaaat caaaaagagc
    46321 ggaaattttt atcgcacaaa cacatatatt ataagcagag cgaaaaactc ttcaattact
    46381 ttcttaaaag tttgtaagaa ttatacaatc tgttaaattt taatttatgt acctaaacta
    46441 cagtattcat tgaacaaatt aggaaacaaa aaagtatacg ctgctaaaat gaattactga
    46501 aattcaaaaa agagagaagc aaactgattc tctcttaatg tatataatat ctagttaaaa
    46561 caaaaagata cgcttacgta tctctgaaa
//
LOCUS       DBERAE010000010        44658 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.10, whole genome shotgun sequence.
ACCESSION   DBERAE010000010 DBERAE010000000
VERSION     DBERAE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.10"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(310..2037)
                     /gene="ezrA"
                     /locus_tag="ACL70N_000729"
     CDS             complement(310..2037)
                     /gene="ezrA"
                     /locus_tag="ACL70N_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGS0589556.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAESYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2119..4065)
                     /gene="gyrB"
                     /locus_tag="ACL70N_000730"
     CDS             complement(2119..4065)
                     /gene="gyrB"
                     /locus_tag="ACL70N_000730"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGS0589557.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4080..4643)
                     /locus_tag="ACL70N_000731"
     CDS             complement(4080..4643)
                     /locus_tag="ACL70N_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0589558.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTSFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4728..5282)
                     /locus_tag="ACL70N_000732"
     CDS             complement(4728..5282)
                     /locus_tag="ACL70N_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGS0589559.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5293..6516)
                     /locus_tag="ACL70N_000733"
     CDS             complement(5293..6516)
                     /locus_tag="ACL70N_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS0589560.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPRLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6553..9003)
                     /locus_tag="ACL70N_000734"
     CDS             complement(6553..9003)
                     /locus_tag="ACL70N_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGS0589561.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVVSLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9203..10132)
                     /locus_tag="ACL70N_000735"
     CDS             complement(9203..10132)
                     /locus_tag="ACL70N_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS0589562.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10272..10559
                     /locus_tag="ACL70N_000736"
     CDS             10272..10559
                     /locus_tag="ACL70N_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGS0589563.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10593..11927)
                     /gene="ciaH"
                     /locus_tag="ACL70N_000737"
     CDS             complement(10593..11927)
                     /gene="ciaH"
                     /locus_tag="ACL70N_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGS0589564.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11917..12591)
                     /gene="ciaR"
                     /locus_tag="ACL70N_000738"
     CDS             complement(11917..12591)
                     /gene="ciaR"
                     /locus_tag="ACL70N_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGS0589565.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12700..15246)
                     /locus_tag="ACL70N_000739"
     CDS             complement(12700..15246)
                     /locus_tag="ACL70N_000739"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGS0589566.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15369..15809)
                     /locus_tag="ACL70N_000740"
     CDS             complement(15369..15809)
                     /locus_tag="ACL70N_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGS0589567.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15784..16653)
                     /locus_tag="ACL70N_000741"
     CDS             complement(15784..16653)
                     /locus_tag="ACL70N_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGS0589568.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16631..17131)
                     /locus_tag="ACL70N_000742"
     CDS             complement(16631..17131)
                     /locus_tag="ACL70N_000742"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0589569.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17142..17840)
                     /locus_tag="ACL70N_000743"
     CDS             complement(17142..17840)
                     /locus_tag="ACL70N_000743"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGS0589570.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17833..18069)
                     /locus_tag="ACL70N_000744"
     CDS             complement(17833..18069)
                     /locus_tag="ACL70N_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGS0589571.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18169..19095)
                     /locus_tag="ACL70N_000745"
     CDS             complement(18169..19095)
                     /locus_tag="ACL70N_000745"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGS0589572.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19170..19985)
                     /locus_tag="ACL70N_000746"
     CDS             complement(19170..19985)
                     /locus_tag="ACL70N_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589573.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(19989..20309)
                     /locus_tag="ACL70N_000747"
     CDS             complement(19989..20309)
                     /locus_tag="ACL70N_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS0589574.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20399..20545)
                     /locus_tag="ACL70N_000748"
     CDS             complement(20399..20545)
                     /locus_tag="ACL70N_000748"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589575.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGRATLTWFEEI
                     FEEY"
     gene            complement(20595..22592)
                     /gene="metG"
                     /locus_tag="ACL70N_000749"
     CDS             complement(20595..22592)
                     /gene="metG"
                     /locus_tag="ACL70N_000749"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS0589576.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22716..23975)
                     /locus_tag="ACL70N_000750"
     CDS             complement(22716..23975)
                     /locus_tag="ACL70N_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589577.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(23977..24678)
                     /locus_tag="ACL70N_000751"
     CDS             complement(23977..24678)
                     /locus_tag="ACL70N_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589578.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24662..25861)
                     /locus_tag="ACL70N_000752"
     CDS             complement(24662..25861)
                     /locus_tag="ACL70N_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGS0589579.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26147..27493
                     /gene="gor"
                     /locus_tag="ACL70N_000753"
     CDS             26147..27493
                     /gene="gor"
                     /locus_tag="ACL70N_000753"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGS0589580.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            27690..28226
                     /locus_tag="ACL70N_000754"
     CDS             27690..28226
                     /locus_tag="ACL70N_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGS0589581.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(28427..28642)
                     /locus_tag="ACL70N_000755"
     CDS             complement(28427..28642)
                     /locus_tag="ACL70N_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGS0589582.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28740..29060
                     /locus_tag="ACL70N_000756"
     CDS             28740..29060
                     /locus_tag="ACL70N_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589583.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29091..29429)
                     /locus_tag="ACL70N_000757"
     CDS             complement(29091..29429)
                     /locus_tag="ACL70N_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGS0589584.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29441..30160)
                     /gene="trmD"
                     /locus_tag="ACL70N_000758"
     CDS             complement(29441..30160)
                     /gene="trmD"
                     /locus_tag="ACL70N_000758"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGS0589585.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30150..30668)
                     /gene="rimM"
                     /locus_tag="ACL70N_000759"
     CDS             complement(30150..30668)
                     /gene="rimM"
                     /locus_tag="ACL70N_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGS0589586.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELTLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30698..31486)
                     /locus_tag="ACL70N_000760"
     CDS             complement(30698..31486)
                     /locus_tag="ACL70N_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0589587.1"
                     /translation="MKRFEVSTEIGSLSVTYKKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(31590..31914)
                     /locus_tag="ACL70N_000761"
                     /pseudo
     CDS             complement(31590..31914)
                     /locus_tag="ACL70N_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(32063..32302)
                     /gene="kphA"
                     /locus_tag="ACL70N_000762"
     CDS             complement(32063..32302)
                     /gene="kphA"
                     /locus_tag="ACL70N_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGS0589588.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32322..32594)
                     /gene="rpsP"
                     /locus_tag="ACL70N_000763"
     CDS             complement(32322..32594)
                     /gene="rpsP"
                     /locus_tag="ACL70N_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGS0589589.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32764..32973
                     /locus_tag="ACL70N_000764"
     CDS             32764..32973
                     /locus_tag="ACL70N_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589590.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33455..33667
                     /locus_tag="ACL70N_000765"
     CDS             33455..33667
                     /locus_tag="ACL70N_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589591.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            33751..34554
                     /locus_tag="ACL70N_000766"
     CDS             33751..34554
                     /locus_tag="ACL70N_000766"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGS0589592.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGNGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34610..36151)
                     /locus_tag="ACL70N_000767"
     CDS             complement(34610..36151)
                     /locus_tag="ACL70N_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0589593.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36153..36635)
                     /locus_tag="ACL70N_000768"
     CDS             complement(36153..36635)
                     /locus_tag="ACL70N_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS0589594.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(36635..37720)
                     /gene="rlmN"
                     /locus_tag="ACL70N_000769"
     CDS             complement(36635..37720)
                     /gene="rlmN"
                     /locus_tag="ACL70N_000769"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGS0589595.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMTIGARHITVSTLGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(37741..38271)
                     /locus_tag="ACL70N_000770"
     CDS             complement(37741..38271)
                     /locus_tag="ACL70N_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGS0589596.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38427..39032)
                     /gene="sodA"
                     /locus_tag="ACL70N_000771"
     CDS             complement(38427..39032)
                     /gene="sodA"
                     /locus_tag="ACL70N_000771"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGS0589597.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39205..40242)
                     /gene="holA"
                     /locus_tag="ACL70N_000772"
     CDS             complement(39205..40242)
                     /gene="holA"
                     /locus_tag="ACL70N_000772"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS0589598.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40276..41211)
                     /locus_tag="ACL70N_000773"
     CDS             complement(40276..41211)
                     /locus_tag="ACL70N_000773"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGS0589599.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(41764..42954)
                     /gene="metK"
                     /locus_tag="ACL70N_000774"
     CDS             complement(41764..42954)
                     /gene="metK"
                     /locus_tag="ACL70N_000774"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGS0589600.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43169..44512)
                     /locus_tag="ACL70N_000775"
     CDS             complement(43169..44512)
                     /locus_tag="ACL70N_000775"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0589601.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
BASE COUNT        13218 a         9776 c         8072 g        13592 t
ORIGIN      
        1 ttattggacg gttaccaagt tactcaaagt acagatttga agctgcagat aagactgacg
       61 aaatcacttt aatactaaat gaaaatcaaa aagcaaacta agaagctagc ctcaggctgt
      121 acttgagtac ggtaaggcga cgctgacgtg atttgaagag attttcgaag agtataaaac
      181 actgttttga ggtggtggat aaatcggctg ggtaaaaact caatctcagg agaaaatgaa
      241 gtaaatctcc ccgcaactat agaaaaagat ttgattctgc tcctcacaca ataaaatctt
      301 tttcttttat taaaaacgaa tcgtttcacg tgttttctca tatgaggtaa caaagcgatt
      361 agttacacca ggctctgcca cttccaatgc ttgagaaatc ttgtcaaatg aagcgtgata
      421 atcaaattct ttttcaaaaa tatctaaagc ttcgttaaat gcttcttgaa tgcgttcatc
      481 aaatgagcga tagcggttag aatattgcaa gagttgctct gtcaaagttg catattgtac
      541 aatattataa gtttccgttt ctaaagcttc catatcattc gttgcaattt caagaactcg
      601 ggtaacagat tcaatgttaa tcattttttg ttctaactca accattaaat cctcggtatt
      661 attgcttgcc gtaaagaata acttcaagaa agtttgtgga atacctggca gattgcgttt
      721 ttccatgtat cgcttgatag tatggagacg attgacataa acattggcct tttgacgtgc
      781 attaatatca tctttctcaa tttgtgtcag gcgctcacta actgaaattt gctcatcttc
      841 aatatctttt agttgagttt gtaaatcctc aagattttct tcaagaactg aataagcttg
      901 ggttggttct tcttgattcg aagttacctc aacaatagct gcctcaaaac tctctaattc
      961 tgtctgaata cgacgaacat ggcttgcagc tgtctcagga agtaaatagg tcttgttcaa
     1021 acgtgcaata tcttctccca ataaagtatt attctctttc atatgttgaa ggtaagttgg
     1081 aagagttgca agtagatttt ccactacttt ctgagcagca atttctcgag taaaaatatc
     1141 atacaaggca ttgatttcct cttgtgcctg tccattctca tattcggcat tatccaattc
     1201 caactgacga atattctctt ggtttttctt gaatgcttca taaagcaagt ggaaacgcgc
     1261 ttcaatatcc gtttcaacaa aatgataatt agcatcaatt agtttacgat aaccggcttc
     1321 caaatcctgt aattgatctg gcaattctgt agaaagcgtc gtaaccaagg ctggaacacg
     1381 atccacaata tgacttaagg ccaaaatgtg attttctgta ttatccaaaa tcactgcggc
     1441 ttccacaggg tcacccgatg aattcaaggt tacaaattgt gaaaattcag attggatatt
     1501 ttctaattgt ttttcaattt catccaaggc ttgaccatac tgttctgaat tttcagcaac
     1561 tctatgctga agttcctcaa ataaatccaa agcatgaaga acacgaccac tatttttaga
     1621 ttcttgcttc tctaagtctg ccaaagcatt gcgaattgcc gcaatatctt cttcaatcaa
     1681 agtaatttga ctctcaattt ggtcaatttg atgactggcc ttgagaaaac gaaatgaatg
     1741 gttatagctc tctgcttcaa agagattatt ttcaatatcg gcaaaagagt tgagagataa
     1801 atcgacccat ttttgattcc attcacggaa agccacttga ctttgtccaa tcaagtgcat
     1861 attttttaca gcttctactt catcatttac tggaagattg tatagttctt cttttctttc
     1921 ttctagtgcc tctaatctcc cctcgtttcg cttacgtaga aagattgcca ctacataagc
     1981 cagaactaaa atgactgcaa ttgcaaccat taaataaatt agttgtccat tagacatatc
     2041 aaactccttt tttacttgaa acaatcgtaa cgattatatc atatttttta gaccaaggga
     2101 actacttctc cctatttttt agacatcaag tgtactatag acagcatttt cttcgataaa
     2161 ctcacgacga ggctctactc gatcccccat caacatatca aagattttat ctgcttctgc
     2221 agcatcatct acagaaactc tagccatcaa gcgatgttcg ggatccatgg ttgtttccca
     2281 cagctgatga tcgtccattt cacctagccc cttataacgc tgaatagtcg gtttggtacg
     2341 accttcacta taacgggcta aagcttcttg gagtttgatt tcttgatctg cacccggctg
     2401 gatatattct ttaatctcgc ttccaacctt gacaccatag attggtggtt gggcaatata
     2461 aacataacca gcttctagga ttggtttcat ataacgataa atcaaggtta aaagaagggt
     2521 acgaatgtgg gctccatcga catcggcatc ggtcatcaaa acgagttttt ggtaacgggc
     2581 tttcgaaaca tcaaattctg cgccaaatcc tgttcccatg gctgtgaaaa gactacgaat
     2641 ttcttcgtta gctagaatct tatccatact tgctttttca acgttcaaaa tcttaccgcg
     2701 aattggaagg atagcctgaa actcacggtt acgaccagat ttggctgatc caccagctga
     2761 gtctccttcg acgatgaaga gttctgtttc agcagggtta ttagaagaac agtctgctag
     2821 tttccctgga aggttggaaa tttccaaacc agatttttta cgtgtgactt cacgcgcacg
     2881 cttggcagcc acacgagcct tggcagccaa aattcctttt tctacgatac gtttggcaat
     2941 ctgtggattt tccatgagga aatcggagaa ggcttcactg aagaggcgat tggtaatctt
     3001 gaccacttcg ctatttccca atttggtctt ggtttgtcct tcaaactgtg gatttgggtg
     3061 tttaactgag ataactgcag ttaagccttc gcgaacatct tcccctgtta ggttgtcttc
     3121 attgtctttc agtaacttat ttttacgagc ataatcattg ataacacgtg tcaaggctgt
     3181 acggaaacct tgttcatgcg ttccaccttc atgtgtatga atattattgg cgaaactcat
     3241 gacattttca tggtaaccag ttgtgtactg catggctacc tcaactgtga tatcatccat
     3301 ctcaccgtct gtatagattg gtgtatcaaa gattacatcc ttgttctcgt tgatatattc
     3361 aacgtaacta gcaatcccac cttcataatg ataatgcttg gtttgttcca aaccttggcg
     3421 cttatcagtg atagaaattt gaagaccgcg atttagaaag gccaactctt gaatccgttt
     3481 atttaattta tcaaaatcaa agattgttgt ttcagtgaaa atttctgggt ccggtgtgaa
     3541 gtgaaccgtt gttccagttc tatctgtatc cccaaccacc tcaaggtctg caacaacatg
     3601 accacgacgg tattcttggt aatgaatctt accgttttta tggacatgaa cgtctaattg
     3661 agtggaaagg gcattaacta ctgacgaccc caccccgtga agaccacctg aaaccttgta
     3721 tccaccaccg ccgaactttc ctccagcatg aaggactgta aagacggtct caacagcagg
     3781 acggcctgtt ttttcctgaa tatcgactgg gataccacgc ccatcatcca caacagtaat
     3841 cgaatcatct ggctcaataa aaacttgaat atggctggca aatcctgcca aggcctcgtc
     3901 aattgagtta tcaacaattt cccagactag atggtgaaga ccttcttttg aggttgatcc
     3961 aatgtacatc cctggacgca tacgaacagc ctctaagccc tctaaaactt gaatttgact
     4021 ggcatcataa tcctgtgcct gcagattttt gatttcttct gtcatcttat tcctttttct
     4081 tatatgtcta atacttgtct taaattcacg atactggtaa acaagtgggt atcaagtcct
     4141 gcagcttgac ctgcttcgat atcaatcggc cgatcaccaa tgacaagacc agagctaatc
     4201 tgatactttt ctcttaaata aagcatggat tcgggatttg gctttctctt aaagcctgag
     4261 ctagaagtca ccacttctgt aaaataagct gctatagagg ttttttctaa aatttccaaa
     4321 acctgatcat ttcgatgaga gaccaaaaaa tgacggccac cttgatttga aatgacttcc
     4381 aataggtcag aaactccttc aaataaaatc gggtgttcaa gctctctggc ttcattttcc
     4441 ttgtactttt ctaaaaaatt ctctaaattg ggagcgaatg tctcaatcgc aaaagaagta
     4501 gaaaccttta aagcttgata gacactgtca tggtcttgtg tgataccata cagtgccaat
     4561 gtttcaacaa atgcagctgt tgaagtttca taattatcca gtaaagttcc acctaaatcc
     4621 cagatgtaat cgtgatattt catacccttc attatagcat ttttttatga aaaaagcgat
     4681 gatttccctg agttttccac ataaaaaacg agagaataac tcccgtttta ctgattttta
     4741 ccaaagacat ctcgatagag cattcctgtt cgtaaactct ctgcgtcccc tcctagttgc
     4801 tccaccaact cgtaggcaaa ggcaagggct gttgaaggac cccgactggt tgtcaactga
     4861 ccatctacca ctactgtttc cttgacgtag tgaccatcaa ggatttgctc ttgaacgccg
     4921 tcataacaag tgtatcgctt atttttcaat atctctgctt gattgagggc aattggtgcc
     4981 gcacaaatgg ctgctagttt cttcccttct tgctcgaagc tttgcaattc ttgaatcaag
     5041 gtctgattat cacgtaaatg tgcagaacca ggcatacctc caggaagaac aatcatatca
     5101 tagtctgata aatttccatc aaagacatga tctgctctta cttggattgc atgcgaaccc
     5161 gttacttgct cttcaaaacc aaccatatca catgtgatat tggctcgacg caagacatct
     5221 acaactgtca aggcttcaat ttcttcaaag ccctgagcta acataactgc tacttttacc
     5281 atgattttct ccttatttaa tttgttttaa tacaaccttt ttccgtttga atgggacttt
     5341 tccgctcttt tcttcagcta gattagtctg gtaactcatc gataaaagca aaccaacacc
     5401 aatcagatta ctgataatag ctgatccccc ttgcgaaatg aaaggcaagg gaatccccgt
     5461 caaaggaagt agtccagtca cagcaccgat attctcaaag atgtggaaga gcaacatcat
     5521 aatcaaacct gtggaaatat aagtgtagaa ctggttattt gatttaagag taatcttcaa
     5581 catacggtaa atcaacatga gatagagggc aataaccagg acagagccaa taaagccaaa
     5641 atcttctgca ataaccgtaa aaatcatatc tgactctcga actgggataa gcagattcga
     5701 agcattaaat ccctgaccaa ataagccacc actcccaatg gcaatctgcc cttgagcctg
     5761 ctggtaagtc gttgtttggg caaactcaaa gggattgagc caagccaaaa tccgattgat
     5821 ttggtaggtc ggcattccaa tctggtgaag aaaagctcgt ccgtccttgc taataaagat
     5881 agctaagaaa ccagcaactc ctgttacagc agtcacaaat actgggataa taattttcca
     5941 agaaacccct gataataaaa cgattcctga gaaaatggct acaaaaacca aagccgtccc
     6001 caagtcactt tgaagtgcta aaagaactag gactggaatg gtaaagagaa tcatccagaa
     6061 aattaacaaa aagtccagcg gaaccgtgcg tctccattcc ttatgtttct ttgtaaattg
     6121 gacaatgaca cgagccaaca tgaggatata agatatcttc ataaattctg acggttggaa
     6181 tagggtaatt ccatttattg atacccagtt tttggcaccc gttgatgcaa ctaatcttgg
     6241 attataaaat acaatcggca agatcataag tcccaagcct aaaatatata gaaagggggt
     6301 caccttccaa agaaattctg tattaaagag catgaccaca aaaccaatca caagccccaa
     6361 ggcaatccag gcgacctgct gccctaaaat gggcaaaata ttattgggat aatcatgact
     6421 aacggctata tagatagcca ccacaccgat gaccagtaga aaaaatactg gcaagagcaa
     6481 actgtaatcg actcttgagt cgagagaacg tttcatatat actaacctta tactttcata
     6541 caatactatt tatcaaagtt cattaaaaaa tctatcaata gcctcgtcaa cttcggatcg
     6601 agagatggtt ttaacagtcg cttcttctgc tagagatact actatttgtt tgccgtatcg
     6661 ttttccgacg attctcctat ccaaaataag agttaaggaa cgttggtatt cacgtctcat
     6721 acttcttccc aaagcctgtt ttaaacgaat aatggccatt ggcaattgat aatcataaaa
     6781 ggcatttttc ccttcttgat tcagttcttg attaatcttt ttcgtcaagg gttcttgagg
     6841 attttggaaa ggaagcctcg gtacaacttg aatcacaaaa ggatggcttg aaaaatcaac
     6901 tccctcccag aaacttgctg caccaagcaa gatttgttgt tcaccttttt caaagcgttt
     6961 ctttagctga tgaacatccc catttttata ctgggccaag tggctaactg taagtaaatc
     7021 cgatactgct agaagcatgt ctttagcggt aaagagaacc aaaatcggtt gctggaaagc
     7081 ttgaatttcc actagtaaag cagctacctc tctggcatag acttctaagg aggtttctgt
     7141 taccagaggg aaatctttga ccatgaccac ttcttgttcc tgttttcccc gagattcaat
     7201 cttgacaaat ttggcttcag gatagcctaa aaggtctgcc aaagaaaccc tctgactaat
     7261 ctcaagagta gccgatactc ccaagacttg gcaactctca ggaagtaaag aggacagaag
     7321 agtacggcat gattttgtag aagaaatctg aattttcttt tgactcgttt cagttacttc
     7381 aagccagtaa tcaccttcag ctgtaaaata gcgaaccagc tcatcaaagc cttctacttc
     7441 taattctgaa aaatactgat ggagattgtc cagagaatct aagatatttt tcctagattt
     7501 accagactga aattgttcta tcaagtagag acactcaaag cgaatacttt ctagtatccg
     7561 ttgttgaacc ctgttttctt ctcctactaa agccttatca attaaatcga taatagattg
     7621 tatatcgtag gtctcttgaa gcagattttc tagagctaac aaaatctttt ggacttcatc
     7681 aataatcagt aaacggtcac tgacaaattc aggattatct tcaagtctgg tcacgagata
     7741 ggcatgatta gtcactaaaa gcttgcaagt ctctgccctt tcttgactac gtttccaaaa
     7801 atcttccgtc acaaataagc tctgggatga taaattccca tcatgacgaa ggtctgctag
     7861 aaaatgttgg taacggtaga gttgcccgat ttcatccaaa tctcctgtct ctgtctcagt
     7921 aagccagacc aagacttgca ttttaaagcg tctaaataag cgattttcat cattttcctg
     7981 caaggaatga taaaaggcat ccaacttcag ataattttgt ggtcccttta agctatgaat
     8041 atctgtatgg aacacttcct tgaggcgttt accttcttct tccatgattt gattttgaag
     8101 aatctttgtc ggaacactaa gaacaatttg tcgctctttg gattgagata aagcgggtaa
     8161 gagatagcca taggttttcc caatccctgt cggcgcttga atcagagaga caggttcatc
     8221 tttcaatagc aagccaacct ctttagcaaa actttcttgt tcctccctca cttcaaggtt
     8281 caacagagaa atatttttag aaaagtcttg agatagtttt cgtggctcca gagaagctgc
     8341 cgttttctta aaatacagac cttgaacttg gaccaagtct ggagaactca ggatagattg
     8401 gttgcgataa gtttcctcaa taaccaggta ggactcatat aggagagcgt cagccatttc
     8461 cagcaagcgt tccaagagac ctttaggaag ctgggtcatc ttttcccgta aaaaaagaag
     8521 taattctgct gtagcttggg catctgaaag ggctgtgtgt gcgtgtttaa gaggaattcc
     8581 taattctcga cacaaaatcg gcaagctata tttttccagt tcagggaaaa agacctgggc
     8641 caattcgacc gtatcaacac gagggtttct tagctcatag ccttcaaaaa ataaattttc
     8701 cgccaagaga ttagcatcaa actgaacatt atgggctaca aaaatcccat cctccaccaa
     8761 gtcaaatatt tttctggcaa cttgcgaaaa atcaggtgct tgcgccagac gttggtctgt
     8821 caatcctgtc agttctttga tatgagcatc caagggttca tgtggattga catccgtcgt
     8881 atagtgatcg acgatttctc cgtcctcaat cacgacaatt cccacttgga taattttagc
     8941 cttactacct gtgctagttg cctctaaatc caccacaaca tagcgattac caatcgtttt
     9001 cattataaaa aattatacca aaaaaagggc catttggcac ctgcaaacat aggataattt
     9061 tcaaactcaa gaacactact tttcttaaaa atcccatcga atagagcatt ctagcctgct
     9121 gatttttgta aaatagtgaa gaaatacgaa aaattgagag aagaaatgtt tgcatcttcc
     9181 ttctctcaac gaatcatgta ttttatctaa ccatgtcagg atcgtagtca taaaatcctg
     9241 tatcaaggaa acggttttta gggtgaagtt tacgaacttc ttcatccagc aagaaggctt
     9301 gatcatggct aaagttgccc tcttgaatca agttacgcgc ttggataaag agttttgcaa
     9361 tctcaacaaa gttctgacca ggagtgtaga gcccttctag tttccagcga gtaaagccat
     9421 gctccaccaa ttctgttaat ttgatcatca aatcaaggtc attgttggca aagatatggg
     9481 tcccatgatt atcttcaaaa atggaatagt ggctctctgg atcacttggc tcagccaaga
     9541 agaggtcacg tttatgcgtc ttttcatcat cgatatgtgt aaagttatag tagttttgca
     9601 agagtggacg tttagaatga tggatgacgc tagcaccgta aaccaaaact tcagcaggaa
     9661 tttccaaaat ctctggcatt ttgaaaagtt cagctgatgg aatttcacgc gccaaaacag
     9721 cctcagatgc gccagccttt tgtccccaga agttaatctg acgactgcta gttaccatgg
     9781 ttgaagcatc gtagatggtc ttaaatgaat aaccatcgcg gttaactacg taaaagacgc
     9841 ctgcatcccc aatcgtaata tagtctgtct tgatttcttc caagaagtct aagaaaggct
     9901 tgatacggtc catcatatct tggtgcatga gagcattgac cgcaacgatc aattccttac
     9961 cagcatcatg aaccaactta gcgatttcac gtaattggtc ataactaaag gtcgttggca
    10021 gacgaaggcc aaaatctttc tcaccgacat agatacggtc tacgccagct tcgagtagtt
    10081 gttcaacttg ttcaatactt tcagcagttg ctgtaatgac aatcttttcc ataagaaaaa
    10141 ttataccaca tttctccaaa atcatccatg ctttgaaaat gaaaagggac tttattcttt
    10201 ttgtaacctt tctgtaataa ttctctgccg aaaaaatgat aaaataggta tgtactgtta
    10261 aggagagaat tatgcccgta agaaaattac aatcctatga ggtagactat caagaagaat
    10321 taaaccagca gcttcctcat taccaagctt atacacctga agcgcaatct gatgccaatc
    10381 tcaaggaaat cctatttttt attaatatcg ctgttttttg tatctgtatt gctatcttta
    10441 gttttatctt tttagcatta aaattatcaa ctgctcttgc ctttgccgca gcaatcggat
    10501 tcagcttact tgttttaaaa gttcaacggt ctattatcaa acgaaaacgt agaagataaa
    10561 tccaaaatat cgccccagtt ggagcgatat ttttattttt tctttttaga tggtgtctga
    10621 atggcaatct tcacttcaaa gattgttccc ttgggtttat tatctttgac agtaacagtt
    10681 ccttttagag catctacaat ttgcttggct agggataatc ctaaaccaaa accacctttt
    10741 tgccgggttc tagccttgtc tactcgataa aaacggtcaa aaattttctt tttatcttct
    10801 gtcgaaatac cgattccatt atcagaaaca agtaaataaa gattgcgatc ggtcgccgag
    10861 ataagaaaat caatttcacc atcctcctca gtatacttga cggcattatc gaaaagaatg
    10921 gtcatcagtt gtttcagaag aagctgatct gtgacaattg ttcgatggat acgattttca
    10981 aaacggaaga cacgattatt ttccgaagca atcatctcgt agtttgtgaa agttgtatta
    11041 aaaaagctag ttggaacttc tgcaagctcc ggcttaatcc catcatctct ccgagctaag
    11101 ttcagcaagc ttgtcgttaa aaaacgcata tttcggactt cttccaaact cgatgcaatg
    11161 ctttcgctca catccataat ggtagcttct ggcttacgaa aaagggtctc taagcgattt
    11221 tgcaaaactg cgagtggagt tcgtaactca tgactggcat tttccacaaa agactgttgc
    11281 ttctgcatac tctcaagcag gggcctaaca ctgaccctag ctagatagag actggcaagt
    11341 aaagacaaaa tccagaaact agccatcacg accacaatca attgctcatg cttttgacta
    11401 gcctgttcca actgactggt attaatcaag acagcagcat acttgatatt ggttgaaacc
    11461 gaactaatat tggtctccat caaaatcaca cgatagattt cttcctgccc atagctatta
    11521 aaaacctgaa tctggtagat atgtcctagt tctttctttt ctaacttaat cttatccaag
    11581 cccaaaaatc gatttccaga aagaagttga gtaaagtctt tatcaaagag aatgacttcc
    11641 gtattggaac tgacattagg ttttatttct actttactag cgtccgccct agcattttct
    11701 aaatctttaa tctcttctgt tgccctattt atagccagct gaataactgc ttgaggattt
    11761 tcactcagtc catgaagctt atcgtccacc gaagtataaa gactcgaatg catgacttgt
    11821 aaaataatca gagtcattgt agaaaaaatc agggtgaaga caccgaagtt gcggataaaa
    11881 taactaaagt catccgcata ccatgttttt ttaagtttac tgaacatctt ttaaaagata
    11941 cccaacacta cgcaaagttt gcaaattctc tgcaaaagtg gttcccttta atttcttacg
    12001 gacttttgaa acatagactt cgacaaccga aatcgttgta tcactatcaa atccccatag
    12061 acggtcaaaa atctgcgtct taggtaaaat cacattttga ttttgaagga aataaactag
    12121 taaatcgaac tctttcccca gcaattcgac aggagtatct tcaactttaa cggtattggt
    12181 tgataaatta accacgatat tcccataagt caaggtgttt tcattaaact tccctgaacg
    12241 tttgagaaga gcctgaatcc gcattttaag ttcttctagg tagaaaggtt tggtcagata
    12301 atcatccgct cccagttcaa atccatgtcc cttgtcatcc aaactttcct tggcagtcat
    12361 aatcagaact ggtgtcgtaa ttcccttttc acgcaattct tttaagactt ggaaaccatt
    12421 tttttctggc aacatcaaat ccagcaaaat caagtcatag acaccactct cagcttcgta
    12481 gagaccttct tctccatcaa atacctgcat aacatccgca aaatcgtcta aaaagtcaaa
    12541 tactgaattt gacagaccta ggtcatcctc aaccaataag atttttatca tgagaaactc
    12601 ctccttatta aaactattat accaaatttg ccttaaaaaa aactcaactc tctgcatttt
    12661 acatgagata gctgagtttt ctttttattt taggcttatt tatgcatttc cgtattgaag
    12721 aacaactgct tcgactgcag ctttttcacg gctaatcaag tcaacacgcg ctgcaatttc
    12781 cttgattccc ataccgatgt tacggctaag agcaaggtca gaaagttgcg gctcaaagaa
    12841 ctccttgtat tccgccaagc gttgctgagt cttaaataca tgagcaggaa ggataacaaa
    12901 gctatcaaag ctcatatctc ctccaagggc tgccttaatc caagcccagt tttcacgcgc
    12961 ccaagaccaa gctgttttct gagttgcttg atgagctagg aattggtaat accaagcaga
    13021 caagtcctgt ggtttgacca caaatttgtc cttccaagaa gtaatcaggt tttggatatt
    13081 atccgcatct gtactgtatg caagagctgc tgccaactgg cgtttaaaga cagcatctgt
    13141 tgcgtgagta taagtatcaa gataaagtgc taacaagtct ttagtctcat gatgtttcat
    13201 ctcattaatc agaacttgtg agcgaatagc tgctgggagt cctgcaagat tctccttgtg
    13261 tgttgcgaag atttggctag cgacttgact agcttctgca tcatttgagc gaatcatcat
    13321 cgaaacagcc agctgacgaa ccaattcatc ctcatctgat tctccgtctt tagcttcaaa
    13381 accaagacgg tcatagttat gacgagccaa tttagcaacc agtcctttga aggctgtttc
    13441 agcatccgtt ccttcatcaa taaagcgctc aagggctgaa atcacttgag aaacagctga
    13501 aaccaccaga taagactctt ccttagcaag tttatcaaga actggaagca agtctgcata
    13561 agaaatgtgc cctgcctcag ccaacaaacg acgttcttga acaatttgca gtttgcttgt
    13621 gttatcaagt gtctctagct cagcaagaac agcttctaac aagtctcctt gatagtcggt
    13681 aatatagtgg gcagtatttt cagtgttgag acgaagagct ccttcatttt cagcaagaag
    13741 agctgcgtag ccagggattt cgatactttc agtttcgagt gtatcaggca agcctttcca
    13801 gttgctattg aggggcacca cccagagacg gttcttgtct tcgttctcac cgatgaagaa
    13861 ttgtttttgt gaaatcttca agacatcatt ttcaacttta acagtaagaa ctgggtaacc
    13921 aggctgttcc aaccaagaat ccatgaaggc tgcgacatca cgtcctgacg cttgaccaag
    13981 ggcatcccaa aggtcactac caatggtgtt gctgtattgg tgtttttcaa agtaggcgtg
    14041 caaaccttta gcaaaatcag catctcctag ccaacggcga agcatgtgca tgagacggct
    14101 tcctttggca tagacgatag cgccgtcaaa gagtgtattg atttcatctg gatgtttaac
    14161 ttcgacgtgg acagactgaa cgccatcagt agcgtcacgt tcaagagcaa gaggtactcc
    14221 acctgtttgg aaatcttcaa agatattcca gcttggttcg atggtatcca cacagacgta
    14281 ttccatcata ttagcgaaac tttcattgag ccaaaggtca tcccaccatt tcatagtcac
    14341 gaggttccca aaccattggt gagccaattc atgggccaca acaagggcaa cttgttgacg
    14401 gctagcaaat gtagagttct catcgacaac caagtaaact tcacggtagg tcacaagacc
    14461 ccagttttcc atagcaccag ctgagaagtc aggaagggcg atgtggagag attgaggaat
    14521 tgggtactta actccatagt aatcttcgta aaactcgata gagcgaacag cgatatccag
    14581 tgagaaatca agatttgaaa gtggatgtgc tttggttgag tagacaccta ccagggtacc
    14641 atttttagtt ttagcggtca ccccttgcaa atcaccagca acaaaggcca acaagtaaga
    14701 agacatgcga ggtgttgtct caaacttcca gatacctgtt tccttacggt tttcaacatc
    14761 gatttctggc atgtttgaca aggccaattc accttctgct tggtcaaagc gaagagagag
    14821 gtcaaaagtt gctttggctt caggctcatc cacacatggg aaagcttcgc gcgcaaaatg
    14881 gctctcgaac tgagtagaca agacctcctt cttgactcca tcaactgtat aataagaagg
    14941 gtaaatccct gtcatgttgt ctgtaatttt accagaaaag gcaagaacca attcaacttg
    15001 accagcctca gccaattcga tatgaagggc ttcattgtca tggtcaactg taaatggacg
    15061 agcttgacct gcaacttcta cagaggtgat ttccaagtct ttttggtgga gggagatgcg
    15121 gtcactctgt gcttgaccag tgatggtcac tttcccagaa aaagtcttgg tctcacgact
    15181 caaatctaaa aataaatcat aatgttcagg aacaaattgc ttaataaaat gttcaactgc
    15241 ttgcatagtt ttctcctatt ctaagtttaa gagctgctgc tcttcttcaa acaaacttat
    15301 tatatcatat tttgcttgag aaaaaaggat tggacagcga tttccaaaac tttcttcctt
    15361 ctaatagtct acagtgggta gaccttgcga aattcttcta aaacaacctt gctttcaggt
    15421 gtaaaagtca gccctacttc acccaaacag tctgtgaaaa agtcctcatg aacctggcgc
    15481 caataggcaa gtgatttgtc tccctcacct tccttaaagg catgttgcgc agaaacttga
    15541 ttgaagagtt caacagaaac ctttgtaatt tcgacaatgc agacagactg attttgacta
    15601 tctaaaatga catcgaaggt ccctacttgg ggaagtggtt cgtcttctag tacatagagg
    15661 tcataggctg atgctgttgc tgtcttttct cctttaaaca ccaaatccgc taaaaggtct
    15721 ggttcaactc caaaagccca agcatcgatt tcatctccga tcaaaggatt gatttgcttg
    15781 tatttattcc acatttcttg cggtatcatg ggtactcctt tgtaattttt tactttcttc
    15841 ttttatgtgt ttaagatgat ctggatggtc aatctctaaa tcaaaaatct ctggaataga
    15901 actgtagtgg ataatgcact tgatacccaa ctgattcatt ttttgtatga aagaagtatt
    15961 cagatagcct gctacagcaa aatcaatctt gttctttctt gctttatcct gcatatctct
    16021 tagcatatct aacattattg gactttccat atcatgccat tgactgtttc tcatagtcgc
    16081 aaaaacaaag gaagtcaaat cattcattcc aactacaatc tttgaaatgc ccgtttccag
    16141 tatcctatcc aagtcaaaat acgctgacgg taattcaatc atcgttccga ctttcccagt
    16201 aaagccatac tgacgcaata ctgtaatagc ttgttttaat tggtcggcat cattgacaaa
    16261 aggaaagata agagatagat tgggattggt ttgataaact tctgtaacga catgtgcttc
    16321 agcctgaaat tcatccaaac acgccagtaa acgcctggtt cctctatagc caaacaaggg
    16381 atgcccttcg tcaaaaaact ctctagtccc cactaaacaa ttggcttctg tattcgttaa
    16441 ttcagaaaaa cgataccaaa cttcttcatc tgagtacagg gagcagatag tctctagata
    16501 atcttttaca aattgctgac aacttgctaa tatgatgttt tgattaagct ctctcaacaa
    16561 atattcccca cgaatcatgc cgacgtggtg aaatagttga ggataaattt tttcaagaat
    16621 tttttcgcca ctaagggcaa gttgatttct catcattcac cttccaattc atgtaagaag
    16681 tcttgtccag ttctggaaat cctaataatt cagacttaac cttcaagact aatggcgatg
    16741 cattttcttc tgtaatctct tgaatatcca tccaaatata tccaagtgaa tcattcgcac
    16801 catcagacac agcttccgaa gtcgtaactt gaggtgcact ctcattcatt tcaacatcat
    16861 acaaggccat gacatggtga accataaaat ttgttaactc ttctctgacg aaaacatcgt
    16921 agattcgagg attagagtag cttctaacag taaatcccgt ctcttccata acttctctag
    16981 tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc tccaggtaga tcataccgat
    17041 gttgataagg gcctctcgtt ttttcaatgc agagtaactt cccattttct aagcaaacag
    17101 cgtagactcc aaagtgtttt ttgatttcca tccaactcct cctacttcaa agaccagcca
    17161 ccatctattg tcaagatttg tccttgcatg gcgctcgctt ttccacttgc taaaaaaaga
    17221 ctaagctctg ctatttcctc tggctcaatc cagcgcttga ttggggtttc actagccacc
    17281 cagtcagcca aaccacctgg ttcaaaatcc gcagcggtca tagctgtctt gactgctcct
    17341 ggagcgatac caaagacctg aatcccagct tcagcatagt ctagagccaa ctgcttggtg
    17401 aagccagcca aggcatgctt ggatgaagta taggcgtgac cacctccacc tgctaggcta
    17461 gaagcaatgg aacacatatt gatgatgatt ccctttttat tttccagcat ttgtgtcaaa
    17521 taataccgag tcaactcaac aggagtcatg tagttaattt caaaaatctc ttgaatttcc
    17581 tgcgcagtct gttccaacag tggtttgtaa gcatccaaaa ctccggcagt attacacaaa
    17641 acatccacct gagggcacca gtcaaaaata ggttccaagt ccaaggtcaa atctctctgt
    17701 aaaaagtgaa aatcaccctc taagagtggc ttttcacctt ggtcaactcc ataaacttga
    17761 tagcccttct ctaaaaagag gcgagcttga gccaatccga tccctgaact cactcctgta
    17821 atgagtacac gtttagtcat gcacttctac ccaatccgtt gccaaaacat cacaagctgt
    17881 cgggctccac atggaaaaac cttctccttc tccagacacg ttgattaaga aataaggtgt
    17941 cacttcaagt gcaagcccat tttgctcgat ggtatcaaag agttggacat agttttcagc
    18001 acctccccaa ccagttcgta catatttttt cttagccttt aagccaggta gaatttcttc
    18061 aaatgtcatg tttttctcct ttaatgtcaa taattctccc cttcattata acaaaaaaac
    18121 cgctttaaaa cggctttttg actgtgattt atttacatct tcttctactt acggcaaatt
    18181 attccctgca gcaagataaa tttcatacca ttcttttctt gttaagctaa agtttgccgc
    18241 ttggctaact tctctcaagt gcttaggatt tgtggtacct acaactgcct gcatttttgc
    18301 tggataacgc aatatccaag aaatggcaat agttgaagag gttactccat atttaatagc
    18361 taaacgatca agtacttgat ttaaagcttg aaatttctca tttccaacaa agttcccttt
    18421 aaaatacccg aattgcaaga cagaccatgc ttgaatgacc acatcgtgta atttgcaata
    18481 ttcaaaaatg ctgccatctc gcatagctgc ttgactatct tccatattaa catgaaaagc
    18541 tgattcaaat cctggagtaa aagccgcact caattgtagc tgattaacag ctaacggctg
    18601 cttgacatct tttttaagca actccatcat cataggattt tgattagaaa ctccaaaatc
    18661 tcgaacttta ccttgtttat aaaggagatc aaaggcttct gctacttggt cagattccat
    18721 caaagcatct ggtcgatgaa ggagcaagct atctagatga tcaatcttca atctttgcaa
    18781 aataccgtct actgatttta taatatagtc cttagaaaaa tcaaaatagg taaattcttc
    18841 aatgcgaatg ccacatttgg actgaatcca catcttttct cttaaatctg gacgattttt
    18901 taggacaaga cctaacagtt cttcacaacg accacgacca taaatatcag ccaagtcgaa
    18961 ggcattgatt ccaacagaaa gtgctgtttc tacaagctct tcaacttctt ttacagactt
    19021 atcttttatt ctcatcattc cgagaacaat ttctgataat tctttgtcat cttgaccaag
    19081 agttatgtat ctcatcaaat ttttctcctt taatttctaa cattcttccc ttcattataa
    19141 caaaaaaccg ctttgcaacg gctttttgac tatacttcac tccattttat cttcttaaac
    19201 ccacggaaca agacaaagat tccaataaag aggacagcta aaggaataac ttttgtaagg
    19261 aaaacatttg aaattcccat ccactcataa taacggagca gagaacccac cacaagatgg
    19321 gcaataatca tactgacaaa tggacgaaag accgcttctt tccaattcca aataccgata
    19381 actagcgaaa tcgtaaagac agacaaacta tcccagggag ccggaatata aaaggctcct
    19441 tcttgtatga agcttgccat tcctacatat cctaaaacaa ctagaagaac tatagtccca
    19501 acaacaatgt aagtgccaat tttcatttta ggagaatctt ggactaaact tcttcgtaaa
    19561 attgtggcca caagtccaaa tccaatcaga aaaataagaa gttgccctaa aaatgtgagc
    19621 aaattgactg ttaagagagg acctttagaa aaatcactta gtagttgata ataacgtaat
    19681 accgccagga caagaattgg cgtcaaaagg gactctttga tagaactgcg aggtgctccc
    19741 ttgagaatct ctttcattat ttttttagga ttcttaccta gataatcctc tgcactcatg
    19801 ccatctcgtt ctgcttctga gaaatctagc atcatcaaat agatctgctc tctgagatag
    19861 tcttcatcat agagaaatcc agcaagatta aaactttccc acaactcctc aaaatacttt
    19921 tgattctcct cagaaaactc atgtagcaaa gcgcttgttt cttcgtaata cttcattttc
    19981 ttcatggttt aacccccatt cttaatccct tctacttttt gactcaaatc gtcccattgt
    20041 tgccaaaaga ctgagacacg ctcttctcct tctttcatta atgaaaaata cttccgatct
    20101 ggaccatctg gcgacgggcg catgtcgcct cttatccatt gatttttttc taacttttgc
    20161 aacaaaggat aaatagttcc tggaacgata gtatcaaatc cagcctctcg caaagtctga
    20221 accaactcat aaccataccg ctctttttga ccaatcatat ccaagacaca accttcaaga
    20281 acacctttta atagctgagt ttctttcatc acttctccct tctaatctat tttgtaatac
    20341 ctactagtaa cttcacctat agtatatcac ttctacacta gtttgtaaag cataatagtt
    20401 aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cctaccgtat gtatggttac
    20461 tgacttcgtc agtttcatct acaacctcaa aacagtgttt tgagcaacct gcggctagct
    20521 tcctagtttg ctctttgatt ttcattgagt ataaataaaa aaacagaact agtctgaact
    20581 agtcctgtct acttttaccc aatcacactt ccatttggta cagctggatc aactgtgaga
    20641 agggttaatt tgccatcatg ttcagctgat agaatcatac cctggctgac atattttttc
    20701 atcattttac gtggtttgag gttagcaacg atttgaactt tcttgccgac caattcttgt
    20761 tcatttggat agtattttgc aattcctgaa agaatctgac gatcttctcc atcaccagca
    20821 tccaagcgga attgaagcaa cttatctgaa ccttctactt tagacacttc tttgacttct
    20881 gcgacacgga tttcaacctt gtcaaagtct tcaaacttga tttcatcctt gtttagtttg
    20941 agctcaactt cgtccggatt ccattctttt tcgactgctg gtttattgcc ttccatttgt
    21001 tccttgatat aggcgatttc ttcttccata tttagacgtg gaaagatagg tgttcctttg
    21061 gcaactacag tcacatctgc tgggaagtca gccaaactca agttttcaag actagaaact
    21121 tcttccaaac caagttgagt caaaactgca cgactagttt ccatcataaa tggttcaatc
    21181 aagtgagcaa ctacacgaat gctggctgcc aagtggctca tgacacttgc caattggtca
    21241 cgaagagctt catccttggc caagacccat ggtgcggtct catcgatgta tttattggta
    21301 cgagagatca gagtccagac tgcttcaagc gcacgtggat agtcaactgc ttccatgtgt
    21361 gtatggaagt ctgcgattga ttgttctgca acctcagcaa gaacatgatc aaattcagtc
    21421 acaccttcta cataggcagg gatttgtcca tcaaagtact tattaatcat ggaaaccgta
    21481 cggttaagga ggttcccaag gtcattagcc aattcatagt tgatacggcc gacatagtct
    21541 tcaggagtaa aggttccgtc tgaaccaact ggaaggttac gcatgaggta gtaacgaagt
    21601 ggatctagtc cataacgctc taccaacatt tcagggtaaa cgacattccc ttttgactta
    21661 gacatttttc cgtctttcat gacaaaccaa ccatgggcaa tcaaacgatc aggtaattta
    21721 acatccaaca tcataagaag gattggccag tagatagagt ggaagcgaag gatatctttt
    21781 cctaccatat ggaagactgt tccattccag aacttgtcaa agttaccatg ttcgtcttga
    21841 gcgtagccaa gagctgtcgc atagttaaga agggcatcaa tccaaacgta gacaacgtgt
    21901 tttggatttg atgggacagg cactccccat gtaaaggttg tacgagatac cgccaaatct
    21961 tccaagcctg gctcgatgaa gttgcgtagc atttcattaa ggcgaccatc tggcgtgata
    22021 aattcaggat gagctttgaa aaattcgacc aaacggtctt ggtatttgct aaggcgaagg
    22081 aagtatgatt cttcagaaac ccattcaacc tcatgacctg atggagcaat accaccagtc
    22141 acatttccag cttcatcacg gaaaacttct gccagctggc tttctgtaaa gaattcttcg
    22201 tctgatactg aataccaacc agagtattca cccaagtaga tatcatcttg agcaagtaag
    22261 cgttcaaaga cctgtgcgac aactttttca tggtagtcat cggttgtacg gataaattta
    22321 tcgtatgaga tatctagtaa ttgccagagt tctttaactc caaccgccat tccatcaaca
    22381 taggcttgag gtgtaatacc agcttcttcc gctttctgct ggattttctg accatgttca
    22441 tcaagacctg tcagataaaa tacatcgtag cccatcaggc gtttgtaacg tgctaggaca
    22501 tcacatgcga tagttgtgta ggcagaaccg atatgaagtt tcccagatgg atagtaaatc
    22561 ggcgttgtaa tataaaaatt tttttcagac ataatttttc ctttccaggc aaatgaaacc
    22621 tgtttttcta acacttcatt atatcacatt tttaatgaat ttcgataggg aaatccatac
    22681 aaaaacaaga tagacgagtg tccatcttgt tgatctcatt cataacgaag ggcttcaatt
    22741 ggatcaagtt tcgatgcctt gttggctggc aagactccaa aaatcatacc aacactagcc
    22801 gaaactgcaa gactaaatag ggcaactggg attgatactc caacttctat accttctatt
    22861 aaaccttgca gtaacaaacc tgctaaggca gttaaaccac ttgcaattgt caagccaatt
    22921 aagccaccta acaaggtcaa aatcatggat tcaatcaaaa actgaattaa aatattggca
    22981 cgtgttgcac ccaaagcctt acgaagacca atctcacgag tgcgctctgt caccgaaacc
    23041 agcatgatgt tcatgacacc agttcctcca acaaagagag aaatccctgc gatggaacta
    23101 ataatcgtcg tcataaaact aaacgattgt tgaatttctg caaatacaac ggactcatct
    23161 gccacctggt attctccctg ttgtaagcct gcaagctctg tcatttttcg tgccagttct
    23221 ggacccagag ttggggttaa actggtatca ttcactcgaa agacaatatt agctatttca
    23281 tctacattaa aattcgcagc aagggagata ttggtagtaa taggcaagcc accaaaccca
    23341 tatatttttg atcttttagc ctccggacta gtataaaccc caatgacccg gtaactaaat
    23401 ccattgactt ctacaacctt gttaatagcc tcttgaggag attcaaataa actaatggac
    23461 aattcctcat ctagcaaaat gacacttgca aactctttga aatcttgctc tctcagacta
    23521 cgacctgcaa taatttcatt cttaacagcg tccatgtaag ttctgtttcc acctgtcaaa
    23581 ttagcattct caaccttttt atcttgatag gtcaagatgg cattcgttga attggttaca
    23641 tagtaactat ccactccctt cagtttagct gcctcttgaa cccaggattc ttgcggtttt
    23701 ggcggttcaa caggaacttc ctcttccttt ccagaaaccg taaaagctga ttgtttctga
    23761 gtaaaagacc catctttact ttttttagga gagaaaaaga cgctaatatt tttctgagat
    23821 ttagtcatat ctttattgac ttgacgagat agggaatcac ccaaagccat aatcacaaca
    23881 actgatgaaa caccgataat aatcccaatc atagtaagca aagaacgcat cttgtgagcc
    23941 atgatagatg aaaaggcaaa tttcagattc tgcatcttag ttttcctcct ttcctaactg
    24001 agcactgtca gacgaaatga ccccatcccg aatgacaatc tgacgtttgg cataggcagc
    24061 aatctcaggc tcatgcgtta ccatgataat ggtttttcct tctttattca aatcaaccaa
    24121 taattgcata atttggttac ctgttttggt atccaaggct cctgtcggtt catccgctag
    24181 gataatagaa ggattgttta ccaaggcacg cgcaatggct acacgttgct tttgaccacc
    24241 agataattct gaaggtaaat ggtgactacg ttctgtcaat tcaaccttgt ctaaatattc
    24301 ctcagccaac ttgcgacgtt ttgaagacga aactcctgcg taaatcaagg gcaattctac
    24361 attttgcaga gcattgagct tcgatagaag aaagaactgc tgaaagacaa aaccgatttg
    24421 ttggttacgg accttagcca gttgtttttc accaagccca gccacttctt gaccttcaag
    24481 ataatattct ccactggttg gtgtatccaa catgccaatc gtattcatca gagtggactt
    24541 accagaccca gatggtccca tgatggctac aaattcaccc tcattcactt ctagattgat
    24601 atttttgaga acctgcaatt cttggtcacc attacggtag cttctgaaga tattttttag
    24661 actaattagt tgcttcatca gccttcacct cttttccttc ttccaaggaa gatgttggat
    24721 tactgatgac cttagcaccg ttcgttaaac cagaagtgat ttcttgattt tctgcgtcag
    24781 catttcccaa tgaaacctca acttttttag ccttttgttg ttcatccaca atccagacat
    24841 aatttttact atcatccatt actagactgc taacaggaac aagaatagcc ttagttttgc
    24901 ttttaacctc aatgttgaca gaaaaacctt gtttcaaatc accaacctcg cctgtcacat
    24961 caatagtata agggtattta gaacctgtat tattcccggc tgctggacta gctgcttcac
    25021 cattgttttt aggatagtca gaaatatagc ttaatttccc agtccatttt ttatcaggat
    25081 acactttaga agtaaagctt acttcttgac ctacagaaag gttggctaga ttgtactcag
    25141 acaattctcc cttgacttgt aaattttcat tgctgacaat atgaaccata acttggctcg
    25201 cccctgttgg agatttagaa acattgctat tgacttcgac tacagttccc tctagggtac
    25261 tgagaacagt tgttgcatcc aattgacttt gagccttact taattgcgcc gcagcatctg
    25321 cacgcgcatc acgggcatca cccaattgag cgtcaataga agcaacagaa tttccagcca
    25381 ctggagttgg gctttgcacc gttgcatctt ctcctcctac tggcgctggt aactgtggag
    25441 ccggagctga agcggcttca tttcgtgctt gattgagttc attgatatga cgatctgcct
    25501 tagctactgc tcgactagct gaatcatagg ccgcctgcgc ttctgaacta ctgtacttga
    25561 ctaaagcctg cccttcgctg accttatcgc ccacagaaac aaggatttca tctaaatcac
    25621 ccttactagc atcaaaataa acatattgtt cattttttgc tgttactgtc cctgacaata
    25681 aaacagagga tgccacgctt ccttccttgg caacaacaag atgagtaggc tcatctttta
    25741 gagcagtctg agaaggttgt ctaaagagta aaatcccccc ggcacccaat acaactacac
    25801 tcgcagcacc gattgctgca tacagttgcc actttttagc tttaccattc tttttcttca
    25861 taatgaaact ccttttcttt tttacaatac tttgctatta taccaaattt ccctccagca
    25921 aacaatgcag ttcagatgga aataatggca gttcaggatt aaacaatcgt tcggaatttt
    25981 gcttttctat tgtactagat atataataca ctatcttgac ttatttggca agcttttttg
    26041 caattttttg tgcgtagcag atttttgcaa tcaaatcaaa aaaagaataa aatataacta
    26101 tcaaaaaaga cactctacta tttaaaagat tacaaaggag ttttcaatga gagaatatga
    26161 tatcattgct atcggtggag gtagcggagg aatcgctacc atgaaccgtg ctggtgaaca
    26221 tggagccaaa gcagccgtta ttgaggaaaa gaaattaggt ggaacctgtg tcaacgtcgg
    26281 ttgtgttcct aaaaaaatca tgtggtacgg ggcgcaaatc gctgagactt tccatcaatt
    26341 tggagaagac tacggcttta agactactga tcttaacttt aactttgcaa ccctacgtcg
    26401 caatcgtgaa gcctacattg atcgcgctcg ttcttcttat gatggtagtt ttaaacgcaa
    26461 cggtgtagac ttgattgaag gtcatgctga atttgtagat tctcatactg taagcgtaaa
    26521 tggtgaactg attcgtgcta aacatatcgt gattgctaca ggtgcccatc caagtattcc
    26581 taatattcct ggtgctgagc taggtggctc ttctgatgat gtatttgcct gggaagaact
    26641 tccagagtca attgccattc taggcgctgg ttatatcgcc gttgaattag ctggcgtact
    26701 ccacactttt ggtgtcaaga cagatctctt tgttcgccgc gatcgtcctt tacgtggttt
    26761 tgattcctac atcgttgaag gtttggtcaa ggaaatggaa agaacaaact taccacttca
    26821 cactcacaaa gtccctgtca agttagaaaa aactactgac ggcattacca ttcatttcga
    26881 agatggtact agtcacacag ctagccaagt tatctgggct acaggtcgcc gtccaaacgt
    26941 taagggcttg caacttgaaa aagctggagt gactctgaac gaacgtggct ttatccaagt
    27001 ggatgaatac caaaatactg ttgttgaggg aatctatgct ctaggtgatg taacgggcga
    27061 gaaagaactg actccagttg caatcaaggc cggacgtacc ctatctgaac gtctctttaa
    27121 cggaaaaact actgcaaaaa tggattactc aactattcca actgttgtct tttcacaccc
    27181 tgctatcgga actgttggtt tgacagaaga gcaagctatt aaagaatacg gtcaagacca
    27241 aatcaaggtt tataaatcaa gctttgcatc tatgtactct gcttgcactc gcaaccgtca
    27301 agaatcccgt ttcaaactca taacagctgg ttcagaagaa aaagttgtcg gacttcatgg
    27361 aattggctac ggcgttgatg aaatgattca gggatttgcc gttgctatca aaatgggagc
    27421 aaccaaggct gactttgatg caactgtggc aattcaccca actgcatctg aagaatttgt
    27481 aaccatgcgt taatcgaaac aaaagaagct gatataaata tgtctgcttc ttttttaatg
    27541 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
    27601 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
    27661 actatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
    27721 ctattggggc tgctctcatt gctgttttgg cacaaatcag tcttccaatt ggacctgttc
    27781 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
    27841 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
    27901 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
    27961 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
    28021 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
    28081 tcctagctgg aatggcattt gaaaaagctc ttgttgtggg ggttcttccc tttatcattc
    28141 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
    28201 aaaatcaggc ttactttact aactaaaaaa ggataccgag ttatcatgac tcaatatcct
    28261 tttttttatt ttgaaaactt atactcaatg aaaatcaaag agcaaactag gaagctagcc
    28321 gcaggctgct caaaacactg ttttgaggtt gtagatgaaa ctgacgaagt cagtaaccat
    28381 acggcaaggc aaagctgatg cggtttgaag agattttcga agagtattag ttgcctttaa
    28441 aggcatccac catcgtttga aattcttcat ttgagagagt aatccctttg cccattttag
    28501 tatggtctgg actccaagca cgaatatcaa actttgcagg ggcaccatta aagctcacac
    28561 ggttaatttc cttggtccaa cctttttcgt tttcagaaag agtcaacaag tgctcttcga
    28621 tttcaaatgt aaattctgcc attttcttct ccttttttag tttcattagt ttattcgtaa
    28681 aatcttgtag attttaggaa aattttatat aatattgata taaaagaagg gaggccaata
    28741 tgagacataa attccagcaa gttctagata aaatacatga ttttttaaat ggacatgacc
    28801 aacctgacca gactgaaacc aactccctta cagccactat tgaagaggct atccagaaac
    28861 aaaccgctgt tcaccttatc ttgtctgaga caagctttac aggtgatatc atcaaatatg
    28921 atcagcaagg ccagcaaatt atcgtgaaaa attttgccaa aaatgtgagc cggattatcc
    28981 gtataagcga tattcaacgc ctgcgatttg tcccctcaac tgtccaaaca gcccaaaaaa
    29041 atagatttaa gaaagagtga gatgtagttg cttcatccca ctcttttttc ttagcgaatt
    29101 tgttcaaaat gtaaatgaac tgcgatatga tctccataac cacttctttc caagtcacgt
    29161 tgtaaacgat aggaaatgta gtgttctgca atggtaatgt aacctgcgcc caataaacga
    29221 tgttcaacca tagattgaat catactgata gtcgcacgtt ccaccttggc ttcttgtaaa
    29281 tccaaaacta ccttcttagt gacttgagca agattttgac gcaaatcatc tgtcaaaaca
    29341 taaacagttt gggctgcctt caagatggct tggtaaatct tatctggatt aaattcagca
    29401 atttcgccat tacgtttgat tacttgcata ggtttctcct ttattctttg ttttctttga
    29461 tttctgccag cattttttct tcttctactg tcagttgata atgttcaagt aaatccggtc
    29521 tgcgctcgta ggttttcttt aaactctcgt acaatcgcca ctgacgaatc ttttcatggt
    29581 ggccactcat caatacatct ggcacgacca tgcctcgata atcataggga cgtgtgtact
    29641 gaggatattc taaaagacct gaagaaaaac tatcatcttg gtggctagac tccttgccaa
    29701 tcacttctgg aatcaggcga actgtagcat caatcatggt catagctgcc aattctccac
    29761 cagtgaggac atagtcgcct agggaaatct catctgttac caaggtctta atgcgctcat
    29821 cataaccctc atagtgccca cagataaaga ttagctcttc ctcttgagcc aaatcttcag
    29881 cataagcctg atcaaactgc tttccagcag gatcgaggag aataacgcgc ggatttttct
    29941 tttcaatagc atcaaaggaa tcgaaaatag gttgtgctct gagcaacatg ccctgaccgc
    30001 ctccgtaggg ctcatcatct acatgacggg ccttttcagc attttctcga aaattatgat
    30061 actggatatc caagagccct ttttctcgag cctttccaac gattgagtgc tccagtggag
    30121 aaaacatctc tggaaagagg gttaaaatat caatcttcat cgtctaaccc ttctaagatt
    30181 tccacatcga cccgtttatt tggaatatca acattgagaa ccactggtgg gatataaggt
    30241 aaaagcaaat cacgtttgcc ttttcgtttg accacccaga catcattagc acctggttgc
    30301 aggatttcct tgatggttcc aaccaagcta tcaccctcat agacttccaa accgataatc
    30361 tcgtgatagt aaaattcacc atcgtctagg tcattcaaat cttcctcagc gaccttgaga
    30421 ctgtatccct tgtacttttc gatagtattg atatggtaca tatctttgaa tttaataatg
    30481 tcaaagttct tctgtttacg gtggctagcg atggtcactg tttggacaaa ctgatctttt
    30541 tcatcaaaca aagtcagctc agctcctttt ttaaaccgtt cttctgcaaa atccgtcaca
    30601 gacaatactc gcatctcacc ctgtaatccc tgcgtattaa cgattttccc aacattaaag
    30661 tagttcatct tgtctcctgt aatctccttt ttccatctta ttctgacaat tctcgaataa
    30721 tagccgcaat tttttccgat tctgaccatt gtaaataatg gtgattcctt cctaaaatga
    30781 gtttagtatt ggaagtccaa tattctgatt ctctgtactc tttttctcta taagtctgac
    30841 aaaaaataaa tacagggaca tgagattcta tcgacaaatt ctcaaaatct tcctcagtaa
    30901 tctctccaga tatctgaaat tctggatctt gattttccaa ctctaagcct ttttcttgca
    30961 ttaattccca gattttttta ttcgtttcag gactaaatgt tgcttgagtt aagttcttaa
    31021 aataaagttc aggaccacac tcgtcaatca gcctcatctg ctcttccatt tctggataag
    31081 gattttctga aaaatcagca aacatgactt ttttagttgt cggttcaatt gctactaaag
    31141 tctgacactt aattggtttc tcgagtaatt tgcaagctaa aattccactc caactatgtg
    31201 cacaaagtat atattcagaa attcctaatt cttcaagtac ttcataaacc gcatctgcaa
    31261 gattatctag attttttcca gcttggtcat gaatcggact cctacctgtg ttcggaaaat
    31321 caattgtcaa ataaccaatt gtaggaggag gtttttcaag tataagtgaa aaattttcat
    31381 aacttggtag caaacctgct ccgtttagac aaactagcac tttcttttgc tttttataag
    31441 taacagagag gctaccaatt tctgtagata cttcaaacct cttcataaag aaatccactc
    31501 attctatata atgaattatt aaaaatcctt atcctttatt ttatcacgtt ccaaagattt
    31561 tctcaagttg gaggaagggg acaatatctc tactttccct tcaagaatcc ttccaaatca
    31621 tgtttatgtt ggtaattaac ggctgcggtt ttgtctttct caaagatggt tctagttagg
    31681 tcaatatgct tgatagcagc aatagcgacg gtgtagtgaa tgatattagc cagttctatg
    31741 gcaggttcct cgttcgaatc ctatcccttc ttttcgacca gagcgcctat tcaaaacctc
    31801 ggctacttct ccgacttcct ccactaactt cataaagaga ccttcatcag tccgagactg
    31861 ctgttaatgt tcgagtaagt agtcttggaa ttgcctaaac gttcaatctt ttatagtata
    31921 ttgaaactag aatagtacac ctttacttct aaaacattgt tagaaatcga tttgactgtc
    31981 ctgatcgatt tgtcctgtta ttatttcatt ttactatatc ttctattcca cacaaaaaag
    32041 cgagacatcc gtcccgccct tcttattttt cgtcaataac gattcttact tttttgtatt
    32101 cagttgggac agagtagaca atcgttctta tcgcagaaat agtgcgaccc ttacgaccga
    32161 ttacacgacc cacatcgctt tgatcaagat tcaaatgata ttccaaaaat tctggtgtat
    32221 cctcaatctt gatagttaag gcatctggtt gtgaaattaa gggtttcaca atcgcaataa
    32281 tgagattttc aatcgtatcc atctgtcaac ctactttaaa cttattttga gaatttagaa
    32341 tcgtggaatt ttttcaatac gccttctttt gaaaggatgt tacgtactgt gtctgaaggt
    32401 tgagctccat tagccaacca tgcaagaacg cggtcttctt tcaaagttac ttggttttca
    32461 gcaacaagtg ggttgtaagt tccaactgtt tcgatgaaac gtccgtcacg tggtgaacgt
    32521 gaatctgcta cgttgatacg gtagaaaggt tttttcttag aacccatacg agtcaaacgg
    32581 attttaactg ccatttttaa agtctcattt ctttaatttt ttatttcggt gaaatagctg
    32641 agctatttag cacatgttct attatagcag atttctggca ggtgtcaaga aaaaaacttg
    32701 acagactata aatttcttaa agcatttaga aatttgttag aataggaaat aaatgtttga
    32761 aagatgctat ccgtgaatac tattttagaa aaattttata aagaacacca agtcaaaccc
    32821 ttcatatcgc ctgaacgaga tttggatact tggcttctaa gtcccaaacc cgttcccaag
    32881 cgaaatatgg acttattagc agatgattca ctagcaggag atatcatttt actatggaga
    32941 atccagtttg gtacttttac cactgaaaca tgattttaaa aactcccatt cgaatatgat
    33001 tcaaaattcg cttagaatca atgttttccc actttttcaa aaaataaatt ttcatctaat
    33061 ttaaataact ttcaattaag tgtgaatttt gcttaaaatc attaaaaaac accccatggt
    33121 gtgaaccatg aagtgttgta aatgctgtgt tgtagctagt tcttagcgtt tagagaactg
    33181 gctagcttta cgagctttct taagatctgg ttccctaaat actttgagta cacttatggc
    33241 attgatgccc caaaacatct aaaaactctg gtagaaaaag ggtatgctct tgtcgaaact
    33301 tcttttgact cacttgacca tctaaataat accatgaaaa agaatatcct gaagaagaag
    33361 aagggagtta ctggactttc taaaatgaaa tcttgcgacc tggatcaagc ccttcatgag
    33421 catttttcag aagaagaatt agctggtcac tttcatgtcc ttctatggac ttttttacaa
    33481 tggcattgct atcacaccca atacctatct aagcgcctgg ttcgtaaact ttattgcagc
    33541 tcttcctcta aatttcctaa ttgttgaacc aattgcccgt tttatactaa gttcttttca
    33601 gaaaccattt actggggaag aagttgaaga ttttcaagat gatgatgaaa tcccaactat
    33661 tatctaagcc agttctgtaa actactaata tttgaaatcc acttcctttt agggtacaat
    33721 ggttataaat gaatttttga gaggatcaga atgaaaaaac tagcaaccct tcttttactg
    33781 tctactgtag ccctagctgg gtgtagcagc gtccaacgca gtctgcgtgg tgatgattat
    33841 gttgattcca gtcttgctgc tgaagaaagt tccaaagtag ctgcccaatc tgccaaggag
    33901 ttaaacgatg ctttaacaaa cgaaaacgcc aatttcccac aactatctaa ggaagttgct
    33961 gaagatgaag ccgaagtgat tctccacaca agccaaggtg atattcgcat taaactcttc
    34021 cctaaactcg ctcctctagc ggttgaaaat ttcctcactc acgccaaaga aggctactat
    34081 aacggtatta ccttccaccg tgtcatcgat ggctttatgg tccaaactgg agatccaaaa
    34141 gggaacggta caggtggtca gtccatctgg catgacaagg ataagactaa agacaaagga
    34201 actggtttca agaacgagat tactccttat ttgtataaca tccgtggtgc tcttgctatg
    34261 gctaatactg gtcaaccaaa caccaatggc agccagttct tcatcaacca aaactctaca
    34321 gatacctctt ctaaactccc tacaagcaag tatccacaga aaattatcga agcctacaaa
    34381 gaaggtggaa accctagtct agatggcaaa cacccagtct ttggtcaagt gattgacggt
    34441 atggatgttg tggataagat tgctaaggcc gaaaaagatg aaaaagacaa gccaactact
    34501 gctatcacaa tcgacagcat cgaagtggtg aaagactacg attttaaatc ttaaaaacca
    34561 aaaaaataca gtatccacat tcggtactgt atttctttta ctctcattct taagttaaat
    34621 tattaaaatc ccatatttgg tctatccagc cttcataaaa gtctggctcg tggcagacca
    34681 taaggataga tcccctatat tctttgagag cgcgtttgag ctcatccttt gcatccacat
    34741 ccaaatggtt ggtcggctcg tccagcacta aaacgttgtt ttcacgattc atcaagagac
    34801 agaaacgaac cttggcttgc tctccccctg ataatacttg aatctggctt tcaatatgtt
    34861 tggttgtcaa accacaacgg gcaagggctg cacggacttc tgcttgatta agggcaggaa
    34921 aggcattcca gacagcttca agaggagttt ggcgattacc gccttctact tcctgctcaa
    34981 aataaccaag ttctaaataa tctccacgct ccacttcccc agcgattggc gagataatgc
    35041 ctaagagact cttcaagaga gttgtttttc caataccatt agcaccaata atcgcaacct
    35101 tttgattgcg ttcgaaggta agatttaaag gcttagtaag aggacggtcg taaccaattt
    35161 gcaagttctt ggcttggaag ataaagcgcc ctggtgtacg agctggtttg aaatcaaagg
    35221 atggttttgg tttctcactt tggagttcga taatatccat cttatccaat ttcttttgac
    35281 gagacatagc catattacga gttgcaacac gggctttatt acgagccaca aagtccttga
    35341 ggtctgcaat ctctttctgc tggcgttcgt aggctgcctc tagctgagat ttcttcatag
    35401 cataaacttc ttggaactgg tagtagtcac cagagtaacg cgtcagctgt tgattttcca
    35461 catgatagac aatattaata acgtcattga ggaatggaat atcgtgcgaa atgagaacaa
    35521 aggcattctc atagttttgg agatagcgct tgagccaatc aatatgctca gcatccaagt
    35581 agttggtcgg ctcgtccaac agcaagatat caggcttttc aaggagaagt tttgccaaaa
    35641 gcaccttggt tctttgccca cctgacaaag aagttacatc cgtatccatg ccaaagtcca
    35701 taacaccaag agcacgcgct acttcgtcaa tcttagcatc caaggtatag aaatcacgac
    35761 tctccagacg gtcttgaagt tctcctactt cttccatgag agcatcaaca tccgcgccgt
    35821 cttcagccat tttcatatag aggtcattga tacgagcttc agctttaaaa agctcatcaa
    35881 aagccgtacg gagaacatca cgcaccgact gtctttcagc aaggacagag tgctgatcca
    35941 agtaaccagc cgtcacatat ttggaccact caacctttcc ttcatctggc agcattttac
    36001 cagtcacgat actcataaag gttgattttc cttcaccatt ggcaccgacc aggccgatat
    36061 gttctccctt gaggagacgg aaggacacat cttcaaaaat tgcacggtca ccaaaaccgt
    36121 gactcagatt tttaacttct aaaatactca ttttaattcc ttatcttgtt tttatgtaat
    36181 cgtttataaa ggagccaagc cagatagcca cccaaagtgt tggtccacaa atcatcaatc
    36241 tcaaagacgc gattgaaatc aaagaaaaag tccaagatta attgcgtaca ctcgattcca
    36301 agactcacaa gaaaactaaa aagaaggacc ttttttgttt tccgcaaatt tggaaataga
    36361 taaaggagtt ggaaaatcag aggaaaaaac aagaagacat tgaggacatt ttgtaaaaaa
    36421 atccaacata attgtccaat gtcactcact tcgcccagtt tccagagaga attgaaagga
    36481 gtcaaaagaa aaaccaggcg tccaagatgc tgaatacctg gagttcccac tcccacggta
    36541 gattgttctt gaggagtaaa gcaaaaacag acaatgcaaa tgctatagaa aatgactccc
    36601 cagaccaaaa tatgattata agtcttcttc atcattaagg atttaccgct gcgactgcct
    36661 tctggcggtc acgtttcatt gtgttagagc gcaattgtcc acaagctgcg tcaatatctg
    36721 taccatgctc ttgacgaacc acacagttga cccctttttt cttaagcgta tcatagaaag
    36781 ccaacacgcg ctctttggga ctacggctat attggtcatg ctcactaact gggttataag
    36841 gaatcaagtt tacataagac aatttcttga tgttcttgag caattcagtc aattccaagg
    36901 cttgttctac actgtcgttg acttcattaa gcatgatata ttcaaaggtt acacgacggt
    36961 ttgttgtctc aatgtagtat tcaatagcag caaagagttt ttcaatcgga aaggcacggt
    37021 taatcttcat gatacttgaa cgaagttcat tgttaggtgc gtgaagagac acggcaagat
    37081 tgacctgaac cccttcatca gcaaagtcac gaattttatg agccaaacct aaggttgaaa
    37141 ccgtgatgtg acgagcaccg atagtcattc ctttatcatc attgatagta cgaaagaaat
    37201 tcaagacatt gttgtaatta tcaaagggct caccgattcc catgacaacg atatggctga
    37261 cgcgttcatc ctgaccacgc tcatcaaagt atttctgaac cagcatgatt tgcgctacga
    37321 tttcaccgtt attgaggtca cgttgcttct taatcaaacc agaggcacag aaggtacaac
    37381 cgatattaca gccgacctga gtggtcacac agacagataa accatagtgt tgacgcatga
    37441 gtacagtctc aattaacata ccgtcgggca attcaaagag atatttgact gtaccatcag
    37501 cagactcttg cacaatacgt tgtttcaagg gattgaccac aaactggtca ttgagcttag
    37561 caatcaaatc cttggaaagg ttggtcattt cttcaaatga ctgcacacgt ttacggtaga
    37621 gccattccca gatttgatct gcacggaatt tcttttctcc ctgctccaat acccattcct
    37681 gcatggtttg atgtgccaaa ctatgaattg agggtttcat ttcttctcct tattctctac
    37741 tcacttctga cgaatgacaa aatgacgttg tcccttgtcc tctttctgag aatgctggtc
    37801 tttctgacga cgtctattct tcttatctgc attcgacttt cgtttagttt gagtcggttt
    37861 ctttcctttt ctagaaggtg tttcttcttc cgtcttacgc attttcttgt caaatgatgc
    37921 tcgcttaggg gcttcatttt ctaagacaaa ataggcacaa ccataactac aatactctaa
    37981 aaggtagtct tgtaaacgac tgattttttc aagtttttct tctgttcggt catccttgta
    38041 aaaacctcgt aggcgaagct gttcgttgct ccagtccccc acgatataat caaacttggt
    38101 taatacttct gaaaaacgct gattaaaagt cgtcacatca aaggcatcct tgatattttc
    38161 aaccaaggaa aaagctatcc cttccgtttc gaccttgtcc ccgtgtaaat ggaactccgg
    38221 accaggaaac ttgttatagt tgtataattc aggtgcaatt tcttttcgca tagatatcct
    38281 ttttccacga ttacttaata ctttattcta ccataatttc tagcagttag cacgtttctc
    38341 ataaaaatga aaaaagtctg acgattttgt cagaccagaa tcttataacc taaaaagaga
    38401 agaacaattc ttccctccaa ctatcattat ttagcagctg cgtacaattc atctacttta
    38461 ttccagttga ttactgaaaa gaaagctttg atgtagtcag gacgcacgtt gcggtatttc
    38521 acgtagtaag catgttccca aacgtccaag cccaagattg gttttttacc ttctgagatt
    38581 ggtgtgtctt ggtttgctgt tgaagtcact tcaagtttcc cttctttgtt gacaaccaac
    38641 catgcccaac ctgaaccaaa acgagttgtt gctgctgcag tgaaggctgc ttggaattct
    38701 tcaaatgaac caaatgttgc atcgattgct gctgccagtt ctgctgaagg agctgttttc
    38761 tcgggagtca tcaattccca gaaaagagcg tggttcaagt gtccgccacc attgttgata
    38821 agtgcttgac ggatatcagc tgggatagat tctacatcag caagcaaggc ttcaaggtct
    38881 tcaccgattt cagggtgttt ttctaaagct gcattggcat tgttgacata agtttgatgg
    38941 tgtttgtcat ggtgcaaatg cattgtttcc gcatcgatgt atggttccaa agcgtcgtat
    39001 gcatatggaa gttctggtaa gataatagcc atctgtaata cctctttttc tttctatatg
    39061 aaaatgataa cgcaaacatt cacttttttc aagttttttg cttatagata aggaaatcac
    39121 tgacatactt tctaataaaa taagcaaatc agcaagaaac ccacgacaag ataatcctga
    39181 cgcgggttgt agtttcaaca aatgtcaatt gacctgacta gcaatctgta agagtgcctt
    39241 ttcaaaaagg aaaccttttt cataaagacc tgtcttaatc tgatagtctg tctcaatcaa
    39301 ataggaaata gcttgcttca gaaagctcaa agaaagtcct ctcgaatctc ttaatgcaaa
    39361 cttgatttga taaggatttg ggttacgtcc cagataacta cctaaactac ttgcaatctg
    39421 cgattctgtt tggccagact ccgccaaaat cttcacctga gtaaaagtcc gaaattgtcc
    39481 cagcatgact gcaatcagtt tgatttcatc ttccccttgc aaggtcaagt ctctcaccaa
    39541 atcgcgcgcc tgatccatct ttttagtcag aataaactga gttaaatcaa aaatattgtc
    39601 ctgcaaggtc ttgggaattg cgttaacaat atcctcttcc tcgataacag aatccgcctt
    39661 ataggactgt aaaaagagaa gatttttctg gatttcgcta aattgaaacc ccgacttgat
    39721 gaggagattt tcaaaagaat gattggtaaa ctgcagacct tgtttctgac tccacttttg
    39781 gaaatactgg cgcaattctt gttcttttac ttctactgca tcgaagacct tggcatcacg
    39841 cttaagtaat ttgactaacc gtcttttgct atccagcttt ccttctgcaa agattatcaa
    39901 cttggttgtt ggagaaggat tgtcaaggta ttcctcaaat gacttaagct catcatctgt
    39961 caaaaagcgt ttcttagcag tcgtgatatc cataaaataa tctaatatca cgattttctc
    40021 atccgcaaag aaaggaaggc tgaccaactc cagttccaca tccttgtaaa ctacttcttt
    40081 catatcaaag taggcaaagt tgaggtcagc agaatcatac ccaatctgtt tcaacacttg
    40141 actcttcatc acttcaaact gaccctgatc tgtccctgta aataggctca ggctcggtaa
    40201 atttgataaa gtcaacttct gactttcttc aatggctagc atcgtctctc ctttcttcag
    40261 atttttcgat ttaatttagt caatatagcg caatttccca cggaaatctt ctaagctctc
    40321 gtagcctttt tccaccatga ttgctttcag ttcattggta atgcggtcaa aagcactgac
    40381 gccttctttg tgaagggtcg ttcccacctg caccatactt gctccacaga ggatgtgttc
    40441 aaaggcatct cgaccagtca gaacgccacc tgttccgata atttggattt gaggatttaa
    40501 acgttgataa aaggcgtgaa cattggctag agcagtcggt ttgatgtatt ctccaccaat
    40561 tccaccaaaa ccattcttag gccgaataac gacagattcg tcttctatat agaggccgtt
    40621 tccgatagag ttaacgcagt tgacaaactt gagcggatat ttgttgaaaa tagctgccgc
    40681 ttgatcaaag tgaacaatat caaaataagg tggcaattta attccaagag gtttggtgaa
    40741 gtaagcaaac acttctgcca aaatccggtc tgttgtctca aaatcatagg caatctgagg
    40801 tttacctgga acatttggac aggaaagatt tagctcagtc agaccacgaa aatcactctc
    40861 ttggactttt ttcaaaatag tatgggtttc ctctggagac atgccgacca gagataagaa
    40921 gaaagttcgg ttcgactctt tttcctgcaa atctaaaaga taatccaaat aatagtctaa
    40981 gccattattt ggcaagccca tagagttgat ggaaccaagt ggaacatctt ggtagcgtgg
    41041 ctcaggattc ccctgacgga agtccaaggt cgctgtctta gtaacaaagg ttcctgccgc
    41101 tgagtttttg acctcttcta actcctctat cgtcatacaa gccacacctg ctgcattcat
    41161 caagcaattg tcaaactcaa aaccagcaat ttgtgttttc gttgatacca tgattctaat
    41221 cctccagatt tcttttattg ctaatattat accataattt taattctagg tttactagat
    41281 tctgtggttc tatctattta ttcggaaaag aaagtctagt acagaagtca tgctatggaa
    41341 acagctagtg tattagaagt ttgaacaagg cttgggtaac agacttttga atgaagtcca
    41401 agcaacaagg agaaatctca accatgagtc cattccatga ctctgttgct ctagaaaacc
    41461 ttgcaatagt caagtgataa cgaataaaac tttggattga aatatcccca agattatcta
    41521 ttacgaggag aaatcttaac ctttatcatt tttaaagaaa tatagtaaaa tgaaacaaga
    41581 acaggagaaa tcgatcagga cagtcaaatt gattgctaac aatgttttag aagttgaggt
    41641 gtactattct agtttcaatc tactatacat gtaaatctct actttcgcaa aatggatttt
    41701 cagaacagta tcccagtata gttaaaaact ataaaaaaga gaggacgttc ccctcttaaa
    41761 atcttatttt actgcttctt tcaaagcatc taccttatcc aaacgttccc atggaagatc
    41821 aatatctgta cgtcccatgt gaccgtaagc cgatgtttga cggtaaattg gacgcttgag
    41881 gtccagcatt tggataatcc ctgcagggcg aaggtcaaag atttgacgag ccgctttttc
    41941 aagttgactt tcagctactg ttcctgtacc gaaagtatcg atacgaacag aaacaggttg
    42001 cgcaacaccg atagcatagg ccaactgcac ttctgccttc ttagcaaggc ctgctgcaac
    42061 gatattcttg gcaatatagc gagccgcata agaggctgaa cgatccacct tagtcgcatc
    42121 tttaccagag aaggcaccac caccatgacg agagtagcca ccataagtat ctacaataat
    42181 cttacgacca gtcaaacctg agtccccttg aggaccaccg attacaaaac gacctgtcgg
    42241 attgataaag aattttgtct tatcatcaag ataagaagat ggaataactt ctttgatgac
    42301 cttgtcaatc acatcttgat ggatttgttc attagtggcc tctggatcat gctgagtaga
    42361 aataacgact gtatctacac gtaccggacg gtcattttca tcgtactcaa ctgtaacttg
    42421 tgattttgca tctggacgga gatagctaat ttctccagac ttacgaagtt ctgccagacg
    42481 acgaaccaat ttatgactga gtgcaattgg caatggcata agctcttctg tttcatctac
    42541 tgcaaatcca aacatgagcc cttggtcacc tgctccaatc aagtccagtg gatcttgatc
    42601 agcatttcca cgaacctcca aggcttcgtt aacaccttga gcgatgtcag gagattgttc
    42661 caccaaagat gggtgtactc ccaccgtctc agcagaaaat ccatattctg tattggtata
    42721 accaatctct gcaatggtat cacgaaccac acggttaata tccacatagg catttgtaga
    42781 aatttcacca aaaacgtgga cagaaccagt atatacagct gtttcagcag caacgtgcgc
    42841 ctctggatcc tttgctaaaa tagcatccaa aatcgcatct gaaatttggt ctgcaatctt
    42901 atccggatgc ccctcagata cagattcaga cgtgaataat ttacgttctg acataaaaat
    42961 gtcccccctt aaaaaatatt gttatagagt tacaaagtac tgataggaaa actcttcgta
    43021 ataaatacct accatcttat cgggactata taactttatc attataccat ttttaatcgc
    43081 aatttgcagt ctttaatgta gtgtttcggt ttagatagtt cgttctcata aagcaaaaag
    43141 ttggagctca gtactccaac aatttctatt aaaatgtttg acgtttagct ttacgctctg
    43201 cacgaccgcg agcgcgattt tcagcacgct tggttttacg gcgcttttca tcaaccgccc
    43261 attgaatttt cttcttataa cccggtttga cttttttctt tttcttttta accaaaccaa
    43321 tcatttcgat atcaagttta tcttgttttt tctcacggtt ggcacgacga tcacggtcat
    43381 aggtatcttg aaattccccg tctttgacca tcttaggact aaacttgatt cccaatttct
    43441 ccaactcacg gatatccgag tcatcacttg gctgataaag ggtaatagct gtacctggta
    43501 ggccatttcg tccagtacga ccaacacggt gaacaaaaaa agataagtct tgcggaatgg
    43561 catcattgat gacatggctg acaccttcaa tgtcaatccc acgtgctgcc aaatctgttg
    43621 cgacaatata ctcaaaatcc agattttgca cctgattcat gattcgcttg cgttcacgag
    43681 gggcaatatc gccatggatt tttgcaacct tcaagccttg agcagtcaga tatgaatgca
    43741 attcatcagc acgcgtttta gtgttaacaa aaatcattgc caaatacggc tgcatcaact
    43801 gagtcaactg gtaaatttga gcattcttat catgtccctt ggtcgaaatc aaccaattat
    43861 caatggtgtc agaaataacc gttttggtct taattttctc cataacagga ttggataagt
    43921 attttttcaa gaatggttgc agtttttgtg ggatagtcgc tgagaagacc atgaattgca
    43981 agtcttttgg aagactgcca gcaatcttat caacagtttc caagaatccc atatccaagg
    44041 tcatatccgc ttcatcaaca acaaatgtct tggctttatg aatagctaaa tcaccagatt
    44101 taaccaagtc gtagatacgg cctggtgttc caataacaat atgaggctga ttgcttgcca
    44161 atttctcaat ctggcgagcc ttatccgtac cacccacata attaaccaca cgaacttcga
    44221 catctgagtg agctgaaatc tgacgcgcta cttggtaaat ttgagtagcc aactcacgac
    44281 tcggtgcagt aatcactgct tgtacactat cgctagcttc atctaattgc tggaaaatcg
    44341 gtaacaagaa agtatgagtc ttacctgaac ctgtttttga ttctcctact aggtcacgac
    44401 ctgccaaaac aataggaatc aacttgtctt gcacctctgt tggagttgta aattttaact
    44461 cctccaaggc ttctctaata tagtttttaa attgaaattt cgtaaatgac ataacatcct
    44521 cgattctatc tatcttatca attataccat attttattcc attacagtag tctcacttat
    44581 ttaggctatt tccagtagct tctctagtaa gaaaaggctg gaattttata ccccaattat
    44641 tcacccctaa tctaaaaa
//
LOCUS       DBERAE010000011        44577 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.11, whole genome shotgun sequence.
ACCESSION   DBERAE010000011 DBERAE010000000
VERSION     DBERAE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.11"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(115..330)
                     /locus_tag="ACL70N_000776"
     CDS             complement(115..330)
                     /locus_tag="ACL70N_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589602.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="ACL70N_000777"
     CDS             complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="ACL70N_000777"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGS0589603.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2501..2857)
                     /locus_tag="ACL70N_000778"
     CDS             complement(2501..2857)
                     /locus_tag="ACL70N_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS0589604.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3095..3331)
                     /locus_tag="ACL70N_000779"
     CDS             complement(3095..3331)
                     /locus_tag="ACL70N_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589605.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="ACL70N_000780"
     CDS             complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="ACL70N_000780"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS0589606.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGSRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="ACL70N_000781"
     CDS             complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="ACL70N_000781"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGS0589607.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4995..6695)
                     /locus_tag="ACL70N_000782"
     CDS             complement(4995..6695)
                     /locus_tag="ACL70N_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGS0589608.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6896..8563)
                     /locus_tag="ACL70N_000783"
     CDS             complement(6896..8563)
                     /locus_tag="ACL70N_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGS0589609.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8566..8931)
                     /locus_tag="ACL70N_000784"
     CDS             complement(8566..8931)
                     /locus_tag="ACL70N_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0589610.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9088..9276)
                     /gene="rpmB"
                     /locus_tag="ACL70N_000785"
     CDS             complement(9088..9276)
                     /gene="rpmB"
                     /locus_tag="ACL70N_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGS0589611.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9392..9628)
                     /locus_tag="ACL70N_000786"
     CDS             complement(9392..9628)
                     /locus_tag="ACL70N_000786"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0589612.1"
                     /translation="MCGFFRYFIPKYVSESRVLYLDLDIVVRKSIDELWDLDLTAIPL
                     AAVRDDFYTHNFNSGVLLINNGMWRAENVTQDLI"
     gene            complement(9779..9877)
                     /locus_tag="ACL70N_000787"
     CDS             complement(9779..9877)
                     /locus_tag="ACL70N_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HGS0589613.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHLL"
     gene            complement(10305..11849)
                     /locus_tag="ACL70N_000788"
     CDS             complement(10305..11849)
                     /locus_tag="ACL70N_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGS0589614.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNKRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12062..12364
                     /gene="gatC"
                     /locus_tag="ACL70N_000789"
     CDS             12062..12364
                     /gene="gatC"
                     /locus_tag="ACL70N_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGS0589615.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12364..13830
                     /gene="gatA"
                     /locus_tag="ACL70N_000790"
     CDS             12364..13830
                     /gene="gatA"
                     /locus_tag="ACL70N_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGS0589616.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLSAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13830..15272
                     /gene="gatB"
                     /locus_tag="ACL70N_000791"
     CDS             13830..15272
                     /gene="gatB"
                     /locus_tag="ACL70N_000791"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGS0589617.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15401..15961
                     /gene="efp"
                     /locus_tag="ACL70N_000792"
     CDS             15401..15961
                     /gene="efp"
                     /locus_tag="ACL70N_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGS0589618.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15983..16372
                     /locus_tag="ACL70N_000793"
     CDS             15983..16372
                     /locus_tag="ACL70N_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0589619.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            16365..16787
                     /gene="nusB"
                     /locus_tag="ACL70N_000794"
     CDS             16365..16787
                     /gene="nusB"
                     /locus_tag="ACL70N_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGS0589620.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQMVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16837..17073)
                     /locus_tag="ACL70N_000795"
     CDS             complement(16837..17073)
                     /locus_tag="ACL70N_000795"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS0589621.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(17086..17559)
                     /locus_tag="ACL70N_000796"
     CDS             complement(17086..17559)
                     /locus_tag="ACL70N_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589622.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17577..17762)
                     /gene="briC"
                     /locus_tag="ACL70N_000797"
     CDS             complement(17577..17762)
                     /gene="briC"
                     /locus_tag="ACL70N_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGS0589623.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17921..18688)
                     /locus_tag="ACL70N_000798"
     CDS             complement(17921..18688)
                     /locus_tag="ACL70N_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGS0589624.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18685..19551)
                     /gene="accD"
                     /locus_tag="ACL70N_000799"
     CDS             complement(18685..19551)
                     /gene="accD"
                     /locus_tag="ACL70N_000799"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGS0589625.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19588..20955)
                     /gene="accC"
                     /locus_tag="ACL70N_000800"
     CDS             complement(19588..20955)
                     /gene="accC"
                     /locus_tag="ACL70N_000800"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGS0589626.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVKKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="ACL70N_000801"
     CDS             complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="ACL70N_000801"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGS0589627.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(21386..21871)
                     /gene="accB"
                     /locus_tag="ACL70N_000802"
     CDS             complement(21386..21871)
                     /gene="accB"
                     /locus_tag="ACL70N_000802"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGS0589628.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="ACL70N_000803"
     CDS             complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="ACL70N_000803"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGS0589629.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="ACL70N_000804"
     CDS             complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="ACL70N_000804"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGS0589630.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="ACL70N_000805"
     CDS             complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="ACL70N_000805"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGS0589631.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="ACL70N_000806"
     CDS             complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="ACL70N_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGS0589632.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(25903..26127)
                     /locus_tag="ACL70N_000807"
     CDS             complement(25903..26127)
                     /locus_tag="ACL70N_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS0589633.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(26187..27161)
                     /locus_tag="ACL70N_000808"
     CDS             complement(26187..27161)
                     /locus_tag="ACL70N_000808"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGS0589634.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(27161..27595)
                     /locus_tag="ACL70N_000809"
     CDS             complement(27161..27595)
                     /locus_tag="ACL70N_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS0589635.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27689..28474)
                     /locus_tag="ACL70N_000810"
     CDS             complement(27689..28474)
                     /locus_tag="ACL70N_000810"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGS0589636.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            complement(28534..28656)
                     /locus_tag="ACL70N_000811"
     CDS             complement(28534..28656)
                     /locus_tag="ACL70N_000811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589637.1"
                     /translation="MKIKEQTRKLAADCSKHCFEVVNKTDEVSSKYCFEVTDGS"
     gene            28844..30208
                     /locus_tag="ACL70N_000812"
     CDS             28844..30208
                     /locus_tag="ACL70N_000812"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGS0589638.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYYAFFGE
                     SKED"
     gene            30211..30582
                     /locus_tag="ACL70N_000813"
     CDS             30211..30582
                     /locus_tag="ACL70N_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGS0589639.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30796..32070
                     /gene="serS"
                     /locus_tag="ACL70N_000814"
     CDS             30796..32070
                     /gene="serS"
                     /locus_tag="ACL70N_000814"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGS0589640.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(32095..32994)
                     /locus_tag="ACL70N_000815"
     CDS             complement(32095..32994)
                     /locus_tag="ACL70N_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGS0589641.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(33104..33652)
                     /locus_tag="ACL70N_000816"
     CDS             complement(33104..33652)
                     /locus_tag="ACL70N_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGS0589642.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33870..35186)
                     /locus_tag="ACL70N_000817"
     CDS             complement(33870..35186)
                     /locus_tag="ACL70N_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGS0589643.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(35277..35365)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(35529..37865)
                     /locus_tag="ACL70N_000818"
     CDS             complement(35529..37865)
                     /locus_tag="ACL70N_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGS0589644.1"
                     /translation="MNKKILETLELDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKVKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYVEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37969..38517)
                     /locus_tag="ACL70N_000819"
     CDS             complement(37969..38517)
                     /locus_tag="ACL70N_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGS0589645.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="ACL70N_000820"
     CDS             complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="ACL70N_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGS0589646.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38903..39784
                     /gene="rnhC"
                     /locus_tag="ACL70N_000821"
     CDS             38903..39784
                     /gene="rnhC"
                     /locus_tag="ACL70N_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGS0589647.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFDYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            39788..40402
                     /gene="lepB"
                     /locus_tag="ACL70N_000822"
     CDS             39788..40402
                     /gene="lepB"
                     /locus_tag="ACL70N_000822"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGS0589648.1"
                     /translation="MNSLKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKLLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            40482..40604
                     /locus_tag="ACL70N_000823"
     CDS             40482..40604
                     /locus_tag="ACL70N_000823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589649.1"
                     /translation="MKIKEQTRKLAVGCLKQWFEVVDRTDEVSSKYCFEVADGS"
     gene            40681..43047
                     /locus_tag="ACL70N_000824"
     CDS             40681..43047
                     /locus_tag="ACL70N_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGS0589650.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLTNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(43095..44378)
                     /gene="tig"
                     /locus_tag="ACL70N_000825"
     CDS             complement(43095..44378)
                     /gene="tig"
                     /locus_tag="ACL70N_000825"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGS0589651.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        13009 a        10181 c         8417 g        12970 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
      121 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata
      421 attagttcag aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
      481 tctacaccat aaatatttgc taataaaaat actgtattat taccctatta aggtgcgaaa
      541 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
      601 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttctctag ctcaaaaact
      661 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
      721 catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca
      781 tccttaatag agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
      841 tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga
      901 gcaaactagg aagctagccg caaattgctc aaaacactgt tttgaggttt cagatagagc
      961 taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtatgactat gcttgtcaat
     1021 agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga
     1081 acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca
     1141 tcttcattat agcacatata catcagttgt acaaataata tgatattttt ttattagtcc
     1201 tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa
     1261 accttccatt ctacggatca aacctgcata atcatgctta tctgccaaag cgatcccaat
     1321 caatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc
     1381 atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgct gtgggaaatt
     1441 gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat
     1501 acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata
     1561 ttcagctaaa acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc
     1621 ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa
     1681 agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat
     1741 cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct caaaggcagc
     1801 tttcatggaa cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc
     1861 cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc
     1921 atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg
     1981 acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt
     2041 aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac
     2101 aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat
     2161 aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt
     2221 tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc
     2281 ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata
     2341 aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac
     2401 cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct
     2461 ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt
     2521 cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat
     2581 aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac
     2641 gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt
     2701 ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt
     2761 ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac
     2821 atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt
     2881 acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc
     2941 gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc
     3001 tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct
     3061 gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc
     3121 atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga gaatgaattt
     3181 caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca
     3241 acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg
     3301 accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca
     3361 actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca
     3421 gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaaca
     3481 aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt
     3541 tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca
     3601 aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg
     3661 attacacgtg aacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc
     3721 attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact
     3781 tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg
     3841 ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt
     3901 tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag
     3961 tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga
     4021 acaccaaatc cttcttcgta agtacgacgt accaagtgtc ccggtccttt aggagcacac
     4081 atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt gaaaccatgg
     4141 gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct
     4201 tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt agcttctact
     4261 actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca
     4321 ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg tccttgtgaa
     4381 ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca
     4441 tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct
     4501 ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag
     4561 caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat
     4621 ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag
     4681 gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa
     4741 tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct
     4801 gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa
     4861 tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa
     4921 cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtagtt
     4981 ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca
     5041 gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga
     5101 acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag
     5161 tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac
     5221 tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga
     5281 ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg
     5341 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
     5401 attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc
     5461 actaactgac gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca
     5521 acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct
     5581 tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg
     5641 actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc
     5701 aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca
     5761 gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc
     5821 gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca
     5881 atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt
     5941 gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat
     6001 tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc
     6061 tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga
     6121 gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt ttctaaagca
     6181 gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg
     6241 acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta attgtactta
     6301 gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt cccaatccct
     6361 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat agcatccgca
     6421 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
     6481 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga
     6541 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca
     6601 ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac
     6661 cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa
     6721 ataacttgtt actatcatac cattttttca aaatttttca agataaaaga agaaattttc
     6781 tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt aaaaagatac
     6841 cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
     6901 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
     6961 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
     7021 caccgacata gaaggttacg atttcactat cttcatccaa catatgtttc aaggtttcag
     7081 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat
     7141 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
     7201 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
     7261 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
     7321 ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
     7381 tgtttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt
     7441 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
     7501 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
     7561 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
     7621 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
     7681 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
     7741 ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
     7801 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
     7861 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
     7921 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
     7981 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
     8041 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
     8101 cttcaacagc gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
     8161 aaactgttaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
     8221 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
     8281 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
     8341 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
     8401 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
     8461 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
     8521 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
     8581 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
     8641 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
     8701 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
     8761 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
     8821 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
     8881 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
     8941 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
     9001 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
     9061 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
     9121 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
     9181 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
     9241 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
     9301 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
     9361 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
     9421 ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
     9481 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
     9541 attttcttac aacaatatct aaatccaaat acagtacacg agactcgctt acatactttg
     9601 gaataaaata cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
     9661 cagaatacta ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt
     9721 ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
     9781 ataatagatg aacacaaaga gattttattg ttgtttcaac tttatccata taagcattat
     9841 ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatctcatt tctttttatt
     9901 cccatcatat gtttctacgt aaccattatt ttcgcccatt cgttcgtaaa accataccag
     9961 tggagatttt agatgaagtc ccattacggt ttacaatttt tacattacga cacggagttt
    10021 tacaaatcga tttcatttgc caaacgtagt tagtaaggca gttagctagg ctacctactt
    10081 tctgctacga cggaaaaatc cacaaatcaa taccattcgt ggatttttcc tagtgaagcg
    10141 tttaggtaag ccgccatagc ggttaccgat tattagatta cgacacggag tttggcaaat
    10201 cgattctatt tgccaaacgt agttagtgag gcagttagct agttcgccaa atagcgacta
    10261 gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct
    10321 aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga
    10381 aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgatga catccgttca
    10441 tccaaatcct caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact
    10501 tccgcattat attctccttc catacggtgc ttaaagactt caaactggag ttgacctaca
    10561 gcgcctagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc
    10621 actagttgct caatcccctt gtggaaggat ttttgcttca tgacattctt agcagaaact
    10681 ttcatgaaaa tttcaggagt aaaggttggc aatggttcaa attcaaattt gtttttccca
    10741 actgtcaagg tatccccaac ctgataagtg cctgtatcgt aaaccccgat aatatcacct
    10801 gccacggcat tggtcacatt ctcacgactt tccgccataa actgggtaac attagacagt
    10861 ttagccccct taccagtacg agggagatta acactcatgc cgcgctcaaa ttcgccagat
    10921 acgatacgga caaaggcaat acggtcacgg tgacgagggt ccatgttggc ttggatttta
    10981 aagacaaagc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg
    11041 tgaccatgtg gttctggagc aaacttgagg aaggtttcaa ggaaggtctg cacaccaaag
    11101 tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct
    11161 gaaaactcat tcccggcttc atttaaaagc tcaatatcat ccttgacttg ctcgtagaaa
    11221 ggattgctac caaaaagttt gtccccatct tctagactag caaaacgctc atccccttta
    11281 taaagctcta aacgtttgtt atagaggtca tacaagccct caaaggcttt ccccatcccg
    11341 ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc ttgtaagaga
    11401 tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaagac tggaatgcca
    11461 cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc
    11521 acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc
    11581 tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca
    11641 gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccaatcaga tttagcaaaa
    11701 gtccctgttt tcttcccttt taccgtacca gcctcacgaa tttcaccccc aaagtagagt
    11761 aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga
    11821 cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgattct ctatttttct
    11881 tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc aacactccat
    11941 tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt
    12001 tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa
    12061 gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc
    12121 tgaaaaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt
    12181 gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac
    12241 tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt
    12301 acctgaaaaa gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc
    12361 ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt ctctaaggaa
    12421 atttctgcaa cagaattgac ccaaacaaca cttgaaaata tcaagtctcg tgaggaagct
    12481 ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat
    12541 gaagctggaa ttgatgctga caatgtcctt tcaggaattc cacttgctgt taaggataac
    12601 atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca
    12661 atctttgatg cgacagctgt tgccaatgca aaaaccaagg gcatgattgt cgttggaaag
    12721 accaacatgg acgaatttgc tatgggtggt tcaggtgaaa cttcacacta cggagcaact
    12781 aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct
    12841 gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa
    12901 cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc
    12961 ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag
    13021 gaaaatgccc tcttgctcag cgctattgcc agcgaagatg ctaaagactc tacttctgct
    13081 cctgttcgca tcgccgactt tacttcaaaa atcggccaag acatcaaggg tatgaaaatc
    13141 gctttgccta aggaatacct cggtgaagga attgatccag aagttaagga aacaatctta
    13201 aacgcggcca aacactttga aaaattgggt gctattgtcg aagaagtcag ccttcctcac
    13261 tctaaatacg gagttgccgt atactacatc atcgcttcat cagaagcttc atcaaacttg
    13321 caacgctttg acggtatccg ttacggctat cgcgcagaag atgcaaccaa ccttgatgaa
    13381 atctatgtaa acagccgaag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg
    13441 ggtactttca gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc
    13501 cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt
    13561 ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg
    13621 tacttagccg acctattgac catacctgta aacttggcag gactgcctgg aatttcgatt
    13681 cctgctggat tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct
    13741 gaggaaacca tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa
    13801 caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatt ggacttgaag
    13861 tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cacttcggaa
    13921 atgatcaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt ctgccagttc
    13981 tcaataaagg ggttgtcgat gccggaatca aggctgctct tgccctcaac atggacatcc
    14041 acaaaaagat gcactttgac cgcaagaact acttctatcc tgataacccc aaagcctacc
    14101 aaatttctca atttgatgaa ccaatcggat ataatggctg gattgaagtc gaactagaag
    14161 acggtacgac caagaaaatc ggtatcgaac gtgcccacct agaggaagac gctggtaaaa
    14221 acacccatgg tacagatggc tactcttatg ttgacctcaa ccgccaaggg gttcccttga
    14281 ttgagattgt atctgaggca gatatgcgtt ctcctgaaga agcctatgct tatctgacag
    14341 ccctcaagga agttatccag tacgctggca tttctgacgt taagatggag gaaggttcga
    14401 tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca agagaaattc ggtaccaaga
    14461 ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc
    14521 aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg
    14581 atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct
    14641 acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc
    14701 ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt
    14761 tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa
    14821 aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg
    14881 ctcagttctt gaatactgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact
    14941 tggttgaaat gattgccatc atcgaagacg gtactatttc atctaagatt gccaagaaag
    15001 tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta
    15061 tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata
    15121 acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag
    15181 gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg
    15241 cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt
    15301 tttttcttct ctcccaactc ccaataacta ttttggcttt atttccagag tattttatgg
    15361 taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt
    15421 aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag
    15481 tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac
    15541 tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga
    15601 gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga
    15661 aacttacgac caatacgaaa tccctgtagt caatgttgaa aacgaattgc tttacatcct
    15721 tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc
    15781 tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac
    15841 aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat
    15901 cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta
    15961 atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc
    16021 cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc
    16081 tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcattta
    16141 tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt
    16201 aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat
    16261 ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac
    16321 accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat
    16381 tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg
    16441 gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa gatacggatg
    16501 tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac
    16561 tagataagca aatcactcag catttaaaag caggttggac cattgaacgc ttaacgctcg
    16621 tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac actcctcaga
    16681 tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc
    16741 gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt
    16801 ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat gataatagat
    16861 ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg
    16921 gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc
    16981 aatcagacta taatataata aactaattgg atctctgtga gatagtatca aatggctaat
    17041 cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg gaaagaaggt
    17101 attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaggcag
    17161 gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa gcacggtaaa
    17221 atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc aaaaattacc
    17281 gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc agttccagct
    17341 ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta atagaaggaa
    17401 acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta accctaaaat
    17461 gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa
    17521 aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac
    17581 cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata
    17641 tagggagcaa attctctata atataaccat ctactatatc catcttccca aacagcaaga
    17701 ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt tgtacctgtc
    17761 attgcaagta ccttcttaaa atagattgtt gtaggttcac atttatagta tatttctttt
    17821 tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa ttacattttt
    17881 ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt
    17941 gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc agctccgttt
    18001 ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt tcagaaatca
    18061 ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc agttctgctg
    18121 cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct ggactgagaa
    18181 tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga gccagagccc
    18241 cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg tcactcattt
    18301 ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg acaccaggat
    18361 aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca gcctgtttca
    18421 tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc cgtttgaggt
    18481 tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga tctccaagcc
    18541 aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca tgtaattgga
    18601 taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg
    18661 cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc tgactaggct
    18721 agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc catgttctaa
    18781 taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat tttcaatcac
    18841 acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat cgccttccat
    18901 agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca ggtaaaagag
    18961 accagcattt gaatggcgtt taaccgccgc agagatctta gccatctgca tgagactcat
    19021 gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg gcaatttttc
    19081 gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac ccatagaagc
    19141 catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa taagagcagt
    19201 tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca gtttcttttg
    19261 gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt ctttgaaggt
    19321 tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg tatagctaca
    19381 gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct tacagcctgg
    19441 acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt ccctaaccga
    19501 acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca ttgattcccc
    19561 ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag gtaagaaggt
    19621 ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg aaatgaggtc
    19681 aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga gggcacgttg
    19741 cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg caatcatact
    19801 atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc gcaagccaac
    19861 tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa agttaaaggc
    19921 tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa tatcttcttg
    19981 cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga tatcaacacc
    20041 tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct ccatgaaata
    20101 gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct catagccaac
    20161 aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt ttccgattgc
    20221 aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac aatcccgttc
    20281 acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa tgtgccgagc
    20341 tggatagata acccgttcta tgtacatggc accattgcca taattggcct tggcctcact
    20401 agaggcagtt tcaaaggcag aaacgaggtc atctggtttt ttaaccttac gaatcccttt
    20461 accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt cagcaacaat
    20521 caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag gcacacctgc
    20581 tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa catgaccaga
    20641 tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg aattttcact
    20701 gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag ctgatagaac
    20761 tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa ctgcttcatc
    20821 tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta ccgtcgcaat
    20881 ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat tggcaattaa
    20941 aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag ggtaccactg
    21001 gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt gccacgacgt
    21061 tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt cttgaactta
    21121 accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt tgataactcc
    21181 aacacaccgg cagtttgcgc caaggcttcc ataatcagaa cacctggcat aactgggtat
    21241 tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat agcaacaatg
    21301 gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg gtggggaaga
    21361 gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta ccaaactcaa
    21421 ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga gctgggattt
    21481 cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg acactatcac
    21541 caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact ccaacaagtg
    21601 gactctctac aagatttccc tcagtagcca cacttgcttc agctggagct ggaacttctt
    21661 ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt gctagaacgg
    21721 gtgctggagc gacttgagtt gcaacttcag gcacaggtct tgcttcattc ttgctaaact
    21781 gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg tcaaattgag
    21841 tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac gtttgaaagc
    21901 aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg gaatttcttt
    21961 ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt cacttgtccc
    22021 agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag cttctactgc
    22081 acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag gtacttcctt
    22141 accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag ttgacgttcc
    22201 gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca aggctagttt
    22261 gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt aggcatcaca
    22321 agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt cagcgtgttc
    22381 aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat tgcgatcctt
    22441 atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg ttaaggcttg
    22501 gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca acatcacatc
    22561 ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg atgaagagca
    22621 ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga
    22681 agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg gtcctttttc
    22741 atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag atgcaacgat
    22801 aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat ttacagcctc
    22861 ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat ctttttttac
    22921 aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat caaagtcact
    22981 atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac tattccaaaa
    23041 ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca ctactcgatt
    23101 tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat caatggcaat
    23161 cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg caacctgctc
    23221 tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa tcttatctga
    23281 taagatagct gtcatatcag actcaatcat tcctggagca atcacattga ctcgtatatt
    23341 ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag ccttagaagc
    23401 agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca tattaatgat
    23461 agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat taaaggcacc
    23521 agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga gcataagagt
    23581 atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt ctgcaatagc
    23641 ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa tgggaaccac
    23701 cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc cacgactgtt
    23761 taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac caattccacg
    23821 actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc tttcaaaact
    23881 tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat cttccacatg
    23941 agctaagtga gcagtttgat caattttttt aacaaagcct gacaagactt tccccggtcc
    24001 aatctctata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt catagaaacg
    24061 aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc
    24121 agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct gagctagagt
    24181 ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac ctgacacctt
    24241 aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc
    24301 aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg gagtaaccac
    24361 tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg tattgagaac
    24421 tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc cacgcttagc
    24481 taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg cagagtattc
    24541 tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca ataaacggta
    24601 gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc
    24661 ttcttccgta tcgatgagat aacgcaaatc ataacctagt acctggctcg ctcgatcaat
    24721 cgtttcttta acaatcggat actgatcata gaaatcccgt cccatcccta gatactgggc
    24781 accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct gtccagcgag
    24841 aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg atttcttcag
    24901 ctgtttcttc tttagaaaca agccctgcga tttgacctgc cataacagag ccaccatcca
    24961 catcaccgtg aacaactgct ttggctagag cacctgctcc catttgttca aagatttcta
    25021 aatcaggatc ttcttgctta aaggcatctt tttcagccag ttcaaaatct ctagtcaact
    25081 gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat
    25141 cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct tttgcaacta
    25201 caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc gcagcacctt
    25261 caccatccgc aattcctcct gcagcaataa caggaataga tacagctgtg gctacctgtc
    25321 gcaccaaagt catggttgtt aatttaccga tatgcccccc agcttccatt ccttctgcaa
    25381 taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcaacacta ggaacgacag
    25441 gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga tttcctgctc
    25501 ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct tccacaaagg
    25561 gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg attttatcaa
    25621 tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct aatcctccag
    25681 ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct ccttggaaaa
    25741 taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct ccaaccttcc
    25801 ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta cctaaacaag
    25861 agggagtggg tttctcccta ctccttctac ttaatattct gcttattttg cttgctcttc
    25921 aacgtaagca accaagtcac caactgtttt caagtcattt tctgcttcga tttggatatc
    25981 aaaagcatct tcgatttctg agattacttg gaacaagtcc aatgaatctg cgtccaaatc
    26041 atcaaaagtt gattcaagtg ttacttctga tgcgtctttt ccaagttctt caacgataat
    26101 ttcttgtact ttttcaaata ctgccatgat aggactcctt taaaataaat agttttttta
    26161 taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc ccaggtcaaa
    26221 cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat gagaccttgt
    26281 tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc atattccatc
    26341 atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt atccaaaata
    26401 cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat aggagattca
    26461 tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa gactgtgcgt
    26521 ccatccatct tcaaaaatga atctgcactt tcttgatctg aaaatggaga atgcaaacct
    26581 gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact ctcagctaag
    26641 aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc aaacaacaca
    26701 gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc aatcaccaag
    26761 cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc aaatacaaat
    26821 ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcaccaat attagcttga
    26881 acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag gatgataaaa
    26941 tccagttctt ttcctgttat tccagctttt gccatcagtt tcttagcaac ctctgtagcc
    27001 aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt tcgacttgaa
    27061 atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac cacttgctct
    27121 ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa tcctccaaaa
    27181 attggtaaag attagtcaag cctttaccca tgacagcaat ttcttcctcg ctcatgccat
    27241 caataatttt ttctaccatg gccttgtgga agcgtttatg cagtctatga atcaagcgac
    27301 ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga actcgctcaa
    27361 tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga gttaccatca
    27421 actcttttga cacttgactt ggagtcacat ctggagcctt accgatgaca tcaatcgtat
    27481 gcatttcttt gatggagata tccttaaaac gactacctct caagttcact tcctcaatta
    27541 caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag tccatttttc
    27601 atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa gaattatatc
    27661 aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt cttcttctct
    27721 ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat ttctgtaggt
    27781 tcagttctaa agtagcgtaa ccctgccagt ctttaaattg gctctcccaa accaacttct
    27841 taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc tgttctctcg
    27901 tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct agggcttttt
    27961 ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca ccgatactgc
    28021 ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca aaggcttgga
    28081 taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata ttcgctgcgg
    28141 cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc ttgattttat
    28201 aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca tcctcatcca
    28261 ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca ttggcattga
    28321 ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct aaaatctcct
    28381 cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta aggattgcca
    28441 agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat tttataagca
    28501 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgtaa cctcaaaaca
    28561 gtattttgag ctgacttcgt cagtcttatt tacaacctca aagcagtgct ttgagcagtc
    28621 tgcggctagc ttcctagttt gctctttgat tttcattgag tgttaaatta tttcactgtc
    28681 aaagtatatc ttttttagga gcagaaagca agaaaaaatc gactgaaagt gtctcagccg
    28741 ataagaaagg ctcgctttag gctagaaagc atcttatttt cttcattgaa aaaagccttt
    28801 ctttctgcta taatcgtata aaatacttac tttaggagtt cttatgaaag ttgttaaatt
    28861 tggaggtagt tctcttgcct ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag
    28921 cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac
    28981 taaggttacg gatgccctga ttaaatacta ccgcgactat gttgcgggta acgatattag
    29041 caagagccaa agctggatta tcgaccgcta tgctgctatg gttagtgaat tgggactaaa
    29101 accagctgtg ctagaaaaaa tttctaaaag cattcacgcc ttggccactc ttcctattga
    29161 agaaaatgaa tttctctacg atactttcct agcagccggt gaaaataaca atgccaaatt
    29221 gattgctgcc tactttaacc aaaatggtat cgatgcacgc tatatgcacc ctagagaagc
    29281 tgggattgtg gtcacaagtg aacctggtca cgctcgcatc attccatcaa gttatgacaa
    29341 gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac
    29401 taaggaaaat caaatctgta ctttctcacg tggaggatct gatattacag gttctatcat
    29461 tgctgctggt gtcaaagctg acctctatga aaactttacg gacgttgatg gtatctttgc
    29521 agcccaccct ggtattatcc accaaccaca ctcgattcct gagttgacct accgtgaaat
    29581 gcgcgagttg gcctatgcag gcttctcagt ccttcatgac gaggctcttc ttcctgccta
    29641 ccgtggaaaa attcctctgg ttatcaagaa taccaacaac cctgaccatc caggtactcg
    29701 tatcgttcta aaacacagta atgatgaatt tccagttgtg ggaattgctg gtgactcagg
    29761 ctttgtcagc attaatatgt cgaaatacct catgaaccgt gagattggat ttggccgcaa
    29821 ggttctgcaa atcctggaag aacttaacat cggttgggaa catatgccaa caggtatcga
    29881 cgatctttct atcattctcc gttctcgcca actaactccc atcaaggaag aagaaatcct
    29941 gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa atcgaacacg acctttctat
    30001 cattatgatt gttggtgaaa aaatgaagag ccatatcgga gtgactgcta ctgcgacacg
    30061 cgctctatct gaaaacaaaa tcaacatcca gatgatgtct caaggttcta gtgaagtttc
    30121 tattatgttt gttgtcaata aagaccaaga gaaagcagca attaaagccc tctactatgc
    30181 cttttttgga gaaagtaagg aagactaagc atggctcaat cacttaacaa aacagtactc
    30241 ctcagtacga caggcacttc ctacctctct atcgctggga aagttgggaa attccttgtc
    30301 ggagatcagg ctttggaatt ttacccagat gtcaatgtcg aacaatttat ccagattcct
    30361 tggagccata tcaatcagat tggagccaat gtcactggac gcaaagtcag ccgccacttc
    30421 gaagtcttta cagacaaagg aaaattcctc tttgcttcaa aagactcagg tgccattctc
    30481 aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca aacttccgac cctgattcag
    30541 acaattagcc aaaaatttaa aaatctattt gcaaaaaagt agaaacttta gtataatcat
    30601 agcaacggat aagtaggtta tcttcttctt tcagaaagtc tgcgggtact gcgagcagat
    30661 aggggggata ggtgaaattc taccgttagt aacaattaca tacacaatca agtgcacacc
    30721 tgtgaagttg gatggaaccg tggccctgcc actccaacgt tttgtcaggc gtgctttttt
    30781 cataaaggag ttcttatgtt agatatcaaa cgtattcgta cagattttga agctgtcgca
    30841 gaaaaattag ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa agaaatcgat
    30901 gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca aagcagaacg taacacagtt
    30961 tctgctgaga ttgcccaagc taagcgcaac aaggaaaata cagatgacaa gattgctgcc
    31021 atgcaaaatc tatctgctga ggttaaagcc ttggatgctg aattggcaga aatcgatgct
    31081 aaattgacag aatttacaac gactcttcca aatatcccag ctgacagcgt tcctgttggg
    31141 actgacgaag acgacaatgt ggaagttcgc cgttggggta ctccacgcga gtttgacttc
    31201 gaacctaaag ctcactggga tctcggtgaa gaccttggta tccttgactg ggaacgcggt
    31261 ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc tcggtgctcg tttggaacgt
    31321 gctatctaca actttatgtt ggatgaacat ggaaaagaag gctatactga agtcatcaca
    31381 ccttacatag tcaaccatga ttctatgttt ggtactggtc agtatccaaa atttaaggaa
    31441 gatacttttg aactcagcga taccaacttt gtcttgattc caactgctga agttcctctg
    31501 acaaactact accgtgatga aatcttagac ggcaaagatc ttccaatcta cttcactgcc
    31561 atgagtccgt cattccgttc tgaggctggt tctgccggtc gtgatacgcg tggcttgatc
    31621 cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac
    31681 gaagaattgg aaaaaatgac agccaacgct gaaaacattc ttcaaaaact caaccttcca
    31741 taccgtgtcg ttgctctctc tactggagat atgggcttct cagctgcgaa gacttacgac
    31801 ttggaagtgt ggattccagc acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca
    31861 gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg
    31921 aaactccttc ataccttgaa cggttctgga cttgcagttg gacgtacagt ggctgcaatt
    31981 cttgaaaatt accaaaatga agatggttct gtgaccatcc cagaagcact tcgtccatac
    32041 atgggtggag ctgaagtcat caaaccataa aaaataaggt ttagctattt ctagctagac
    32101 cttttttcgt aaccaaatca gataagcacc tagtacaaag aataaaatag ttaggcatat
    32161 aatggtttca gccaatacca ggtaatccag aaatggaagt ttcaaaattc cctgagccat
    32221 cttgagcgag gtcgctgtga taatggttgg gaaggtgagg gctgagaagg ctggttgaaa
    32281 accttgtttt aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg attgagaagc
    32341 caaaatcatg acaatcaaga cccaagtcgg caggctggtt cctcctactc gaactagaga
    32401 agccaagagt agagagaaag gagcacagta gattccttct tgtccaagca aggctagtgg
    32461 gagtggatgt ttctttaaat cgctataaat aaggggatag agatagaagg tcaagagaaa
    32521 accaaaactc aaggtcgcat aggcaatttc gataatacct accagaggat aggtcaaggc
    32581 agccactgct atccccacat agagaaccgt ccagcttgga gtggcatgaa ccctccgccc
    32641 tggacaagca aacttgatgg taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa
    32701 ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga cataggtcga
    32761 taaaatcatc ccagccatag gaaaggttgc cattcctgac aaaagagggg gcttggtcaa
    32821 ttcttgcttg gtttctttcc aattaaagag atgcagaatt agaaagtaaa tccataaaac
    32881 caaaccagtc agactaaaaa gatgggatag aaccggcaac gtatctaaaa taagatttcc
    32941 agctcctgcc aaacctagca aacaacctga aaatactaag gggagttttt tcatcctaac
    33001 ctccaataat catgttagtt tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa
    33061 acgaagtccg attatttcag acttcatttt actcagatat gaattaggca taaggttgca
    33121 attctggatt aattggtgta ttagctaagt tgttggcata gttacagagg attgctaggc
    33181 tgacaccaaa aaccacatcc aaggcatttt gttgagtgta gccagcttct aaaaactcag
    33241 acaaggcttc atctcctaca cgacccttgg tattgataac tgccaaggta aacttagcta
    33301 gggtatccaa tttaggatct gtttcaattg gagtacgatt gcgaagagct tgaatcaagt
    33361 catcattcat ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac
    33421 aaccattggt cacggctgcc gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt
    33481 tgcgacggtg gatagatgag acaatttggt aggcttctaa aacagtcggg gcattggcca
    33541 agagaccgat taggttggga atatagccat tgttgtcttt ttctactgtt tcaagaattt
    33601 ctttcacttc tgctggtgct gactctactg tatggatagt aaatgttgtc ataagatacc
    33661 tcttttctta ttattgacac taatattatt ggaaaatctt ataaaatcct gattcctaag
    33721 tttatctaag ataaagcttt attctctcat aagattttcg ttgttatatt agtttatcac
    33781 acttccaatc acttgcataa tatatattat atatcaggct gataaaaatt atttataggc
    33841 aaaaaaatca cacgagctgt gtgattccat tatttgttaa aatacttttt agtttcagca
    33901 ataacgactg gcgacaagac caagagggca atcaagtttg gcagagccat caaggcgtta
    33961 acgatatctg cgataatcca gaccatatcc aactcgataa atcctcctaa caagaccatg
    34021 agcacaaaaa acacacggta gagccagata aagcgagccc caaagaggaa ctcaaaacag
    34081 cgttctccgt aatagttcca acctagaatc gttgtaaagg caaaaagtac aaggaagatg
    34141 gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga aagctgactg agtcaaggca
    34201 accccattca agtcaccact ccaaactcca gttaccaaga tggtcaaacc agttagagta
    34261 caaatgatga gggtatcaat aaaggttcct gtcatggaaa tcaaaccttg ctctactggt
    34321 tcatttgtct tggcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    34381 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    34441 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    34501 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    34561 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    34621 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    34681 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    34741 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    34801 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    34861 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    34921 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    34981 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    35041 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    35101 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    35161 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    35221 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    35281 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    35341 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    35401 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    35461 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    35521 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    35581 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    35641 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    35701 tggtcgatga aggtatctag ctcattcatg gcttctacat agcgcttgcc tcgaagatcc
    35761 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    35821 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    35881 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    35941 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    36001 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    36061 accttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    36121 atctggtcac tttcacttaa ggccatatcc acaatctcag cagcctgttc acgcgccttg
    36181 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    36241 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    36301 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    36361 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    36421 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    36481 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    36541 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    36601 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    36661 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    36721 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    36781 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    36841 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    36901 gttaaatctt gaccaaaata gacatcattt gcgacggcat ttttgaccaa aggatggcag
    36961 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    37021 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    37081 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    37141 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    37201 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    37261 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    37321 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    37381 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    37441 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    37501 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcgta aaaactttga
    37561 agttctcggc tggtaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    37621 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    37681 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    37741 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    37801 aaatgaggct caaacaaggc cttgacctta tcgagctcta atgtttctaa tattttctta
    37861 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    37921 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    37981 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatactct ggatgatgtg
    38041 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    38101 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    38161 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    38221 caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac ctgcataaaa
    38281 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    38341 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    38401 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    38461 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    38521 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    38581 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    38641 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    38701 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    38761 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    38821 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    38881 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    38941 tcaggctttt cttgaacact atcaaaccag tctggctcct agcaagaatc cctatatccg
    39001 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    39061 tcagggtgaa ggggctgaaa aatacgccag tttctttgac tatcaagctg tagagcaaac
    39121 cagcggacaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    39181 tgggcttgca gttgtggctg cctttgtcac acctgaccag cacgactttt tacgaaaact
    39241 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    39301 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    39361 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    39421 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    39481 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    39541 agaaaaggct gagggcaaat acttggctgt cgcagtttct tctgtcattg cgcgtgatct
    39601 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagcttc caagtggagc
    39661 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    39721 caacttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    39781 gtaagttatg aattcactta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    39841 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    39901 catggatccg accctagcgg atggcgaaat tctcttcgtt gttaagctcc tccctattga
    39961 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacattg tcaaacgtgt
    40021 catcggaatg cctggcgata ccattcgtta cgaaaatgat aaactttaca tcaatgacaa
    40081 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    40141 aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    40201 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    40261 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    40321 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    40381 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcacaaat ctcagcctct
    40441 tcttctatcg tgagaagtga ttgtttattg acaaatactc aatgaaaatc aaagaacaaa
    40501 ctaggaagct agccgtaggc tgcttaaaac agtggtttga ggttgtggat agaactgacg
    40561 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    40621 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    40681 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    40741 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    40801 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    40861 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    40921 aaaccaacta gtaagggatt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    40981 ctcaagacag ctcagaaaat cgtagatacc tatggcgaaa ataccattga tgaaattttg
    41041 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    41101 gtctccactc tccgtctcaa ctacggaacg gagatggttt tggccaaact agccaactac
    41161 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    41221 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttacaatt
    41281 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    41341 ggtctagttc acagtctttt tcaggcctgt atggaaacag gagacaccta tgttgaagca
    41401 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt agaactagac
    41461 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    41521 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggtatccg cagtcacttg
    41581 attcgtatcc ttgaaaaagg agaacagaag agacaagatt tagaaactat tcaaaagcat
    41641 atcactactg tcgagcaaga actggggatt gagtatgata acattcaaaa acaagctatt
    41701 tgtgacgcta tccagaacaa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    41761 actgttatca atggaatcat cgctgtttat gcccttttag aaggacttga cttcaggaag
    41821 aaaagcaatc tgcccattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    41881 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    41941 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    42001 atggtagata cttggctgac caatcaactc ttctccaata tctcttctaa cagtaagatc
    42061 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    42121 ctgcttcata ttcctttgat tcctcagact cgcttggaaa aaatttatcg acaaagcaaa
    42181 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    42241 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    42301 attgaaaaaa tcttaggtgt cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    42361 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    42421 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    42481 aagagagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    42541 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    42601 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    42661 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    42721 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    42781 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    42841 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    42901 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    42961 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    43021 gacctcaaag agatttttgg aaaatagtac atcagaaaac ccaccaattc aggtgggttt
    43081 tctgtttatt aagattattt tactgttgct gtgcttgtga tcaattcaac agcttttttg
    43141 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    43201 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    43261 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    43321 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtgatttg gaagtacatg
    43381 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    43441 tcttcatgga tcatttcttc tggaagttct acgatttcag cgttttctac agctgtatca
    43501 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    43561 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    43621 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    43681 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    43741 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    43801 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    43861 gaaccaacga agtcgatcac aacagtgtcg ccgttttcag cagcagcttc cttgataacc
    43921 aattcagcca gattgttgcg ttcgcgttcg atacgctctt caacatcagc gtcagttact
    43981 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    44041 tttgtaacga cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    44101 atttttggtt gggcaaccac ttcaagacca gcttctttta cagctgcttc ataagcgttt
    44161 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttgtcgaag
    44221 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    44281 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    44341 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    44401 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagccaat
    44461 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    44521 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttcagt
//
LOCUS       DBERAE010000012        43178 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.12, whole genome shotgun sequence.
ACCESSION   DBERAE010000012 DBERAE010000000
VERSION     DBERAE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.12"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..187)
                     /locus_tag="ACL70N_000826"
     CDS             complement(<1..187)
                     /locus_tag="ACL70N_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS0589652.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTK"
     gene            complement(309..2267)
                     /gene="ftsH"
                     /locus_tag="ACL70N_000827"
     CDS             complement(309..2267)
                     /gene="ftsH"
                     /locus_tag="ACL70N_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGS0589653.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNKARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2283..2825)
                     /gene="hpt"
                     /locus_tag="ACL70N_000828"
     CDS             complement(2283..2825)
                     /gene="hpt"
                     /locus_tag="ACL70N_000828"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGS0589654.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEVDYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2829..4106)
                     /gene="tilS"
                     /locus_tag="ACL70N_000829"
     CDS             complement(2829..4106)
                     /gene="tilS"
                     /locus_tag="ACL70N_000829"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGS0589655.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(4103..5371)
                     /locus_tag="ACL70N_000830"
     CDS             complement(4103..5371)
                     /locus_tag="ACL70N_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGS0589656.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5364..5486)
                     /locus_tag="ACL70N_000831"
     CDS             complement(5364..5486)
                     /locus_tag="ACL70N_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGS0589657.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELTDKNQLLRLQEEKERKNA"
     gene            complement(5491..5859)
                     /locus_tag="ACL70N_000832"
     CDS             complement(5491..5859)
                     /locus_tag="ACL70N_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGS0589658.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5852..6118)
                     /locus_tag="ACL70N_000833"
     CDS             complement(5852..6118)
                     /locus_tag="ACL70N_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS0589659.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6186..9695)
                     /gene="mfd"
                     /locus_tag="ACL70N_000834"
     CDS             complement(6186..9695)
                     /gene="mfd"
                     /locus_tag="ACL70N_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGS0589660.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9696..10265)
                     /gene="pth"
                     /locus_tag="ACL70N_000835"
     CDS             complement(9696..10265)
                     /gene="pth"
                     /locus_tag="ACL70N_000835"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGS0589661.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10336..11451)
                     /gene="ychF"
                     /locus_tag="ACL70N_000836"
     CDS             complement(10336..11451)
                     /gene="ychF"
                     /locus_tag="ACL70N_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGS0589662.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11535..11729)
                     /locus_tag="ACL70N_000837"
     CDS             complement(11535..11729)
                     /locus_tag="ACL70N_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGS0589663.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11794..12930)
                     /gene="dnaN"
                     /locus_tag="ACL70N_000838"
     CDS             complement(11794..12930)
                     /gene="dnaN"
                     /locus_tag="ACL70N_000838"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGS0589664.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(13089..14450)
                     /gene="dnaA"
                     /locus_tag="ACL70N_000839"
     CDS             complement(13089..14450)
                     /gene="dnaA"
                     /locus_tag="ACL70N_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGS0589665.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14663..15421)
                     /locus_tag="ACL70N_000840"
     CDS             complement(14663..15421)
                     /locus_tag="ACL70N_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGS0589666.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15479..16660)
                     /locus_tag="ACL70N_000841"
     CDS             complement(15479..16660)
                     /locus_tag="ACL70N_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGS0589667.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16843..17322
                     /gene="rlmH"
                     /locus_tag="ACL70N_000842"
     CDS             16843..17322
                     /gene="rlmH"
                     /locus_tag="ACL70N_000842"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGS0589668.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEELSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17366..17439
                     /locus_tag="ACL70N_000843"
     tRNA            17366..17439
                     /locus_tag="ACL70N_000843"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17400..17402,aa:Arg,seq:tct)
     gene            17605..17730
                     /gene="comC"
                     /locus_tag="ACL70N_000844"
     CDS             17605..17730
                     /gene="comC"
                     /locus_tag="ACL70N_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGS0589669.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17751..19076
                     /gene="comD"
                     /locus_tag="ACL70N_000845"
     CDS             17751..19076
                     /gene="comD"
                     /locus_tag="ACL70N_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGS0589670.1"
                     /translation="MDLFGFGTVIVHFLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            19073..19825
                     /gene="comE"
                     /locus_tag="ACL70N_000846"
     CDS             19073..19825
                     /gene="comE"
                     /locus_tag="ACL70N_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGS0589671.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19877..19948
                     /locus_tag="ACL70N_000847"
     tRNA            19877..19948
                     /locus_tag="ACL70N_000847"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19910..19912,aa:Glu,seq:ttc)
     gene            19954..20027
                     /locus_tag="ACL70N_000848"
     tRNA            19954..20027
                     /locus_tag="ACL70N_000848"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19988..19990,aa:Asn,seq:gtt)
     gene            complement(20068..20610)
                     /locus_tag="ACL70N_000849"
     CDS             complement(20068..20610)
                     /locus_tag="ACL70N_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS0589672.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20738..22387
                     /locus_tag="ACL70N_000850"
                     /pseudo
     CDS             20738..22387
                     /locus_tag="ACL70N_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22417..24969)
                     /locus_tag="ACL70N_000851"
     CDS             complement(22417..24969)
                     /locus_tag="ACL70N_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGS0589673.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQALKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISITSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTYKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(25031..26653)
                     /locus_tag="ACL70N_000852"
     CDS             complement(25031..26653)
                     /locus_tag="ACL70N_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589674.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26859..27884
                     /gene="trpS"
                     /locus_tag="ACL70N_000853"
     CDS             26859..27884
                     /gene="trpS"
                     /locus_tag="ACL70N_000853"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGS0589675.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            28036..29514
                     /gene="guaB"
                     /locus_tag="ACL70N_000854"
     CDS             28036..29514
                     /gene="guaB"
                     /locus_tag="ACL70N_000854"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGS0589676.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29565..30662)
                     /gene="recF"
                     /locus_tag="ACL70N_000855"
     CDS             complement(29565..30662)
                     /gene="recF"
                     /locus_tag="ACL70N_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGS0589677.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30665..31033)
                     /gene="yaaA"
                     /locus_tag="ACL70N_000856"
     CDS             complement(30665..31033)
                     /gene="yaaA"
                     /locus_tag="ACL70N_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGS0589678.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            31192..32442
                     /locus_tag="ACL70N_000857"
     CDS             31192..32442
                     /locus_tag="ACL70N_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS0589679.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32439..33722
                     /locus_tag="ACL70N_000858"
     CDS             32439..33722
                     /locus_tag="ACL70N_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS0589680.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33764..34585
                     /gene="rodZ"
                     /locus_tag="ACL70N_000859"
     CDS             33764..34585
                     /gene="rodZ"
                     /locus_tag="ACL70N_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGS0589681.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34596..35141
                     /gene="pgsA"
                     /locus_tag="ACL70N_000860"
     CDS             34596..35141
                     /gene="pgsA"
                     /locus_tag="ACL70N_000860"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGS0589682.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            35138..35965
                     /locus_tag="ACL70N_000861"
     CDS             35138..35965
                     /locus_tag="ACL70N_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGS0589683.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35950..36789
                     /locus_tag="ACL70N_000862"
     CDS             35950..36789
                     /locus_tag="ACL70N_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGS0589684.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36782..37576
                     /locus_tag="ACL70N_000863"
     CDS             36782..37576
                     /locus_tag="ACL70N_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0589685.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37635..38453
                     /gene="mreC"
                     /locus_tag="ACL70N_000864"
     CDS             37635..38453
                     /gene="mreC"
                     /locus_tag="ACL70N_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGS0589686.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38453..38947
                     /gene="mreD"
                     /locus_tag="ACL70N_000865"
     CDS             38453..38947
                     /gene="mreD"
                     /locus_tag="ACL70N_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGS0589687.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            39041..40219
                     /gene="pcsB"
                     /locus_tag="ACL70N_000866"
     CDS             39041..40219
                     /gene="pcsB"
                     /locus_tag="ACL70N_000866"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGS0589688.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40443..41222
                     /gene="rpsB"
                     /locus_tag="ACL70N_000867"
     CDS             40443..41222
                     /gene="rpsB"
                     /locus_tag="ACL70N_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGS0589689.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGHQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41301..42341
                     /gene="tsf"
                     /locus_tag="ACL70N_000868"
     CDS             41301..42341
                     /gene="tsf"
                     /locus_tag="ACL70N_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGS0589690.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42656..42910
                     /gene="tnpB"
                     /locus_tag="ACL70N_000869"
     CDS             42656..42910
                     /gene="tnpB"
                     /locus_tag="ACL70N_000869"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0589691.1"
                     /translation="MDSLAYVVKTHFELDSFSGQVFLFCGGRKDRFKALYWDGQGFWL
                     LYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFSITPKI"
     gene            complement(43051..>43178)
                     /locus_tag="ACL70N_000870"
     CDS             complement(43051..>43178)
                     /locus_tag="ACL70N_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGS0589692.1"
                     /translation="RKRGFKNKAFRTLEDVIQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT        13517 a         7464 c         7929 g        14268 t
ORIGIN      
        1 acttggtttt gaaatatttc cttaaacgtg gaatatcgtc taccagtcct tcttctctac
       61 taatcaattc atgtaagcag agcatgcctt cttggtccca atccgataat tcccataaat
      121 gaaggtaata ttcatttcta cacttataca cagtcccttg gacttcttca tacaattctt
      181 taatcataat tttccccttt ctagatacag tctaacagat tagaaaacac atttgttcca
      241 ttttctccat tctgttccct ttagctccta aactgcacaa aaaagagagg ctccagcctc
      301 tctcagggtt atttttcgtc attcattttt gactttactt catcatagga tagtgcatga
      361 gattcctctt ctactgcttc aggcatcttt cctgtttcgt aaagagcttt aatttgtgta
      421 ctatccaatg tttcgtattt caataatgct tctgcaatta acttgtgagt ttcacgattt
      481 gactgaataa tttcagcagc tttatttcgt gccttattta ataatgaacg aacctcttca
      541 tcaatttcat aagctgtttg ttctgaaatt gatttttgag gattctgtgc accaaacata
      601 gcatggtttc cttcatattg tactgggcca agtttttcac tcataccgta ctctgtaacc
      661 attgcacgtg ccatttgtgt cgcttgttca aagtcgtttg aagctcctgt agtttggaca
      721 ttaaagataa tttcttcagc tacacgtcca cccattaagc cagccaattg ctctttcata
      781 tcttctttag atagaagcat ttgatcctct ttaggaagtg caatcatgta tccgcctgca
      841 cggccgcgtg gtacaattgt aaccttatgg acaacgcgag cattcgacaa gactagacca
      901 acaatggtat gtcctgcctc atggtaagca accaattctc gttctttttg tgaaactgtc
      961 ttatctttct tagaaggtcc agcaataact ctatcttctg cttcatcaat atctgaagca
     1021 tcaattatcg atttattgcg acgagcagca actaaagctg cttcattcaa gacattctct
     1081 aaatcagcac caacaaagcc tggagtttgt tgagccacta atttcaaatc aacatcttct
     1141 gctaaaggct tgttcttagc gtgaactttc aagattgctt cacgaccttt aacatcagga
     1201 cggccaacca atacttttct atcaaaacgt cctggacgca aaagggcagg atcaagtaca
     1261 tctgaacggt ttgtcgcagc gatgacgata atcccttcat ttccctcaaa accatccatc
     1321 tcaatcaaaa gttggttcaa ggtttgttca cgttcgtcat tacctccgcc gagaccaact
     1381 ccacgttgac gtccaacagc atcaatttca tcgataaaga tgatagctgg tgctgctttt
     1441 ttggcatcct caaaaagaga gcgaacacga ctagctccaa ctccgacaaa catttctaca
     1501 aagtcagaac ctgagatact aaagaatgga acacctgctt ctccagcgac tgccttagca
     1561 agcaaagtct tacctgtccc cggaggtccc tccaaaagaa cacctgctgg aatacgggct
     1621 ccaagttttg tgaatcgttt tggatctttt aagaactcaa caacttcaac tagttcttgt
     1681 ttttcttcct cagctccagc aacatctgaa aatcttactt taatatcttc tttatttgct
     1741 gctttagcct tactacgtcc aaaactcatt ggattacggc cattgcctcc tcccatattt
     1801 cccatcatag agaataggaa gaagaataga attccaaatg gcacaatgga tacgagtaga
     1861 ttaatccata taccacttga actttcatgc ttaacagtta cttctgcttt atggtcagta
     1921 gcaagttttt gcaattctga tacggtagta tctgcaggaa gaatagtgct ggtaaatttc
     1981 tctaccttag taacagatgg cgtgaaaaac tgaatacctg ttccttcttt acttgtttta
     2041 ggatttttat agacaccaga aacttcgata acactaccat ttggttggta agttaattct
     2101 tttacattac catcggtaat ttcttgtacc aactcagtat agttgatttg ctgacttcct
     2161 cctgagttat tcccagaata gaaatactgg aatcctgtca caaggaaaaa gataaataat
     2221 aaccatagaa aaggattttt aattaaacca ttattttgtt ttttcattaa agattattct
     2281 ttctaatttg aatacacttc ctctttcaat actccaatat aaggaagatt acgataattt
     2341 tctttgtagt ctaaaccata acctactaca aactcatttg ggatagtaaa gcaggtatag
     2401 tctacctcaa tttctacaac acgtccttct ggtttatcca acaaggttgc aattttaaca
     2461 gaagctgctt ctctttcttt aaacatatct cgcaaattct tcaaagtttg acctgtatca
     2521 atgatatctt ctacaaatag aacatgtctt cctttgatat cttgagtcac atcttgttta
     2581 atattgataa caccactact tgctgttcca ccatggtagc tagaaaccat catgaagtcc
     2641 atttcaatat gtgtatcaat atgtttgacc aattcagcca taaaaggaat agatcctttt
     2701 aaaatcccaa ctaagattgg attttttcct gcatagtctt tagttaattg agcacctagt
     2761 tttttagctg cttctgtaat ttcatcgtgt gaaacgagga cttttttaat atcgttttct
     2821 aacatttttt acctatctat tttttctata taaagtacag tgttcattat atcatttttc
     2881 gtttttttac tcaaattatt ggtcgcaatt cccaaaattg agacaatttc accaaattgc
     2941 tcaataataa gagcagagtt tctcttttcc atagggattt tcaaatcaat aaataaacgt
     3001 ctgagttttt ttctatgccc attttgaatc aaaacatctc ctgtttttcg atgacgaatg
     3061 tgtatggatg tttcacgtga aacaggtatt tgttgaatta attcaccttc taatggaagt
     3121 ccaaaggaaa ataaatatcc ttgataagct acctgatttt gatagtgtaa cacaagttca
     3181 tcttcctttt catcagcctg cggactgatt ttacaaatct gaaactgttg gtactctttt
     3241 atcaattcat agccattttt aatcggatga cgatactggc ttttagattt taaaatctgc
     3301 tgaacttcag caaactgagt ttttgtaaga ttcaaatctg gaaaacgatt cagataagtt
     3361 tgaagtaaaa ctctttgtgt agactcagag taagaaaata actgctgtaa atcttccaca
     3421 ttaatattgt tagataattc agctattgcc aaatcataat ctaaaatttc attgccaatg
     3481 cctaagattg catccctaaa tcgaggattt tctttttcca attttggtaa gtaagaattt
     3541 cgaatacgat ttcgaaaata atgattctcc tgatttgatg tatcttcaaa gtgaaaaatt
     3601 gatggaaagt cttttttctg aaaatgcaag aagggacgaa tgatttctat ctctccgact
     3661 acttgcttct ccttaattcc tgatagatag cgcaagcgag ttcctcgaat caagcgcatc
     3721 aaaatcgttt ccacctgatc atcagcatgg tgggcagtga ctaaagctgt cgcacctgtc
     3781 tttttcatga cctcttgaaa aaaatcataa cgaaaatttc gtgcacgcgc ttctgaaaat
     3841 tctcctgaaa aattgctgat ataaatagga agctctgctt cagcagccaa cttccttaat
     3901 tccttttctt cccaatctga ttcaattctc tgcttatgat tcacatgagc cagaatcaat
     3961 tcaatctcta actctttttg ataagtagac aataccttaa atagaaacat agaatctaat
     4021 ccaccagaaa gagctagaac cgccttagca tgctttttga aatatccctt cttgagaaaa
     4081 tgatttaaaa aatctggttc cctcatttta gaacctcata aacatccttg gctatcttag
     4141 aaatcgtatc ataatcagaa ttcttagtga aaatagaaag aataaatgga gaatctgcat
     4201 agacaacacc cgtatcatgc ttaaattcat ccgcatctcc aattttatga gctactttaa
     4261 cagaaacacc tttggcaatt cgctgactat caaaatctgt tttagtcaaa gactctagca
     4321 caaatccatt ttgattataa atagcttcca taaacttccc ggccatctta gaagaaatca
     4381 atttttcttt tggatcccaa tcatctccca taatggcaga catcttggat ttgaatgtgg
     4441 catcagattg gtttgaaatg taatatccca atagattatg agctacatta tcagattctt
     4501 ttgatacttt cgtaattaaa tcctttaaag aatattcttt attatcttct tttttaggaa
     4561 gactaccact tccctctggt ttataagaac ctggaaaatc attgactgca gatacgtatt
     4621 ttacagtcgt atctaactga taaagaccct catttatttt ttcttgcgta taatagagat
     4681 aggagagttt caaaacgctg gctgcataca tcttttcatc ttgattgata ccagcttctt
     4741 ttccagtagt cagttgctta acataaatag agaaagaatc tttctgatat ttttcagata
     4801 acatttcttg aactttactc atccgattat cttcttcaga agttgattct ttagctaccc
     4861 atccagcctg atcaatatgt agaaattctc ttccttctac aaacatggtc ttgtcgattg
     4921 atacttgcga ataagctgat aaggatgatt tcacttcttt taaatcataa ggactattgt
     4981 acagtttaaa gtcagattct aaccatgctt tttttattgt tggagttacc tctgattgat
     5041 catataaaaa tcgtttgtcc gcagctataa attgatgatt tgatagctta aatactggaa
     5101 ttccttgttt atttaagcgc cactcggtta tttgaaaact tgttttggga gtcaatttcc
     5161 cagattccac tactaaatct tcattcgcat aaacaggaac ctctccataa accatgggag
     5221 aacttaattt ttctctaaaa taaataccaa agtcagattg tgaaaggtaa taaatttctt
     5281 tcgaagtata gacgacttct ttttctgtgc taacgacttt tgaaatggtc aaaaaacttg
     5341 gtagcaacaa aataattaag aatttacgca ttcttccttt ccttttcttc ttgtaaacgc
     5401 aataattgat ttttatcagt caattcttcc agcttttcat ctgacaaact caaaaattgc
     5461 tctattacgt ctaataaatt ttccatttta tcacctttga agcaagtcag gaatcgtata
     5521 aactttttcc ctcgacttag aataatagta cttcgctcgt gtatatttag cagcataatc
     5581 ttcatctttc aacttggtag caaatgctgt ttccttatcc ttttcatcac tcaaagtttg
     5641 atactgagtt tgcaagtctg ctaattgctg acgtctttgg agtaattgct gataactctg
     5701 cgccaaatta aaagttggca agataaataa tagcataatc aaaatcaata ccccccccat
     5761 aaaacgattc cgtttttgtc gttctttcat caggtagcga cgacgttggt attcattttg
     5821 aataaaagaa ttattcaatt gtacaatatt tttagacatt ttcttctacc cgtgtttcac
     5881 tgataatttc atacattcct gctgcatctt ctttttttgt actatctttc atctctagta
     5941 cttttacaag cagcaactta ttgccaaagc gaatttcaac ttggtcatta actttcaagt
     6001 ccgttgaact tttggccaag attccattaa ccttgattct acctttatct gctacttcct
     6061 ttgcgactgt acgacgcttg ataattcgcg atacttttaa atatttatct aatctcatcc
     6121 ttattacctc aatttattat tgtaccattt ttatctattt ttatctattt tatagaagaa
     6181 aaatatcaaa tggaattttc ttccttaaac tcttttatct ctaataaact ttctccaaaa
     6241 atcagcagac cttctaaaat ttcataatct ttcttatttt ggacatcaaa tacaagctcc
     6301 attaatccct tattctcagc gatgcctgct tttaagttcg ttacggataa agctttaaaa
     6361 taatcttgag ctaaaaacag tcgttgagtg actttttcaa attgaattgt aattttatta
     6421 tcttttcttt ccacacgttg aacaaagacc ttgtccaagt atgatttgac caaaccaatc
     6481 tctaaaagat aggctactac atctgggtat tctccaaaac ggtctatcaa ctcctcttgt
     6541 aactcttcat aattgacacg gttgtcaatt tgacgaattt tcttgtaaat ttcaatctta
     6601 tgtcgttgat cagaaatata agtatcagga agataggcat caatttgcaa aatcaactca
     6661 gcattccctt tggttcttgt gttagcgtta gcattaccgt ttcgtttagc aatagcttcc
     6721 tctaataact gcgaatacaa ttcaaaacca acagaatcaa tgaaaccaga ctgggatttt
     6781 cctaaaagat ttcctgctcc acgaatcgaa agatctcgca ttgcaatctt aaagccagag
     6841 cccaattctg taaatccttt aatcgcttct aatctctttt cagagacttc actgattgat
     6901 ttttctggac gatacatgag ataagcataa gcaatacgat tactacgacc gactcttcct
     6961 cttaactgat ataaggttga caagcccata tggtccgcat tttcaataaa taaagtatta
     7021 gcatttggaa tgtccacccc tgtctcaata atagtagtcg tcaccaagat atcgtattgt
     7081 ccctcaataa agtctaatag agtattttcc aactggactt cactcattcg accatgaaca
     7141 tatccaatcg aagcctccgg aatcaactcc tgtaattctg aaaccttctg aacaattgtg
     7201 tcaactttgt tgtaaagata gtaaacttga cctccacgct ccatttcacg caagacagca
     7261 tcacgaatga cactatcatt cttttccaaa acataggtct gaacaggata gcgattagtc
     7321 ggcggagttt caataacaga caaatctctg attcccagca tagacatatg gagggtacga
     7381 gggattggcg tagcggtcaa ggttaggaca tccacttgtt tcttcagttc tttcaaagtt
     7441 tccttatgct tgacaccaaa tcgctgttcc tcatcaataa tcatcaagcc caaatcagca
     7501 aacacaacat cttttgacaa aacacgatgt gttccaatca aaatatcgac ttgaccgttt
     7561 ttcaattttt caagtgttgc agtctgctct tttttacttc taaagcgact caacacatca
     7621 acattaactg caaaattttg gaatcgttcc ttaaaattcg tatagtgctg ttgcgctaaa
     7681 accgtcgtcg gaactagaat gacaacctgt ttgtgatcat tgactgcttt aaaggctgca
     7741 cgcatagcaa cttcagtctt tccaaaacca acatccccaa ctaaaagtcg atccattggc
     7801 tgagaagcct gcatatccct tttgatttcc tcaatactac gaagttgatc atccgtttca
     7861 acataaggga aagcatcatc aaaggcatct tgatcatcat catcagctga gaaagcaaaa
     7921 cccttcaact gactacgttc agagtagagt ttgattaaat catcagctat atcctctacc
     7981 tggttcttaa ccttttgctt ggccttttta aaatgaccgt catttaattt attgagtttt
     8041 ggagctttac catcacttga aatatatttg gacagtagat gaatctgttc cacggggata
     8101 gaaatttgat caccattttg gtattggaca ctgacataat cgcgatgaat tcccttgatt
     8161 tcaatggttt caattcctag atattgacca atcccatgga tatgatggac aacatagtcc
     8221 cctttttcaa gttcattgta atcttttaat ctctctgcat ttgaaacatg ttgtcttcga
     8281 aaacgacgct ttaatttctt ttgaaaaatc tcatgttcag ttatcaataa aatcttttca
     8341 tctacaaaat gaaaaccatg tctgagatta ccctctatta agtttacaga ttctttacag
     8401 atatttgtct tatctctaga atccaattta atctgatatt cctctaacat atcctccaat
     8461 gttttacttc ccattgaatt gctagactgc agaataatgg tgtaatccat ttttttatat
     8521 cgttcaattt cttcttttag aaaagaaaac tgattgaaaa attcctgcat aggatattga
     8581 ttgaattgat aaattttgtc aaatttgaga tttcctaaac ccttttgaag attagagaaa
     8641 aaggtcactg gactttgttt tttatagatt tgttcaatat cagaaaaata ctgcatatca
     8701 gaaaatgctt tactattctg taattcttct gtaaagtact gcgctaagtc tctttcaaag
     8761 acttcatact gattcatcaa tttttgataa tcatcaaaga atattggagt atctttttca
     8821 atataatcaa agacagtcca tgtcttatca tagcacaaag ataaaaactt ccgagagtct
     8881 gcatgacttt gtttttggtg aaaacttgaa agaatttctt ctaggtatga tttcaaaata
     8941 ggtgataaag tttttgaaat ttgtttttct aaagctgact gtcctcgttg ataatccttt
     9001 tctctcaaaa gcatatcact agctggaaag atagtgagtt ctgtcttatt ttctttcgat
     9061 aattgtgttt ctacttcaaa tgacctgata ccatcaattt catcaccaaa aaactcaatt
     9121 cgacaaggtt ctaactggga tatttcaaaa atatctaaaa tatctcctcg aagactaaat
     9181 tcgccctgag tttgtacttg agtaactttt cgatagccat tttcctttaa ctgatggata
     9241 aacgcgtgtt gatcatattc ttcaccaact gagattttta caatactatc tttgaatgca
     9301 ttgggagacg gtaaaatcaa tcgacttgct gcgatattac aaactaaaat ccctttctta
     9361 gatgaatcag tcaaaaaacg caaggcttca acccgtgaaa taattttttc ctgtgaagac
     9421 atcaaaaact ccaccatagg agcatcatct accaaaaatg gatagacgag ttcctcaccc
     9481 aagatagata taagatcact aacaagtcct tctgcttctc cataagttga cgtcaataac
     9541 acaatcctat cttctttttc taaactgctt gcaattgcaa gagccttagt agatgttgat
     9601 aaaccaagta ttagttgtct tttcttatca gttaaatttt gatgccattt tttaatctga
     9661 tcattttctg agaataaatc taataaggtc accatttatc cgttatacct ctgcattgtt
     9721 ttctcaaaat ttttctcttg taaatagtag tttacagaat cgtcaacttt gtcaacagac
     9781 tgtaaaatac cgatataatc atccctgtca aacttactca aaacatgatg aacaactgac
     9841 ataccatttt taggtcttcc aattccaatc ttaacacggt taaagacctg agttcctata
     9901 tgttgaataa tagacttgat accattatga ccacctgctg agccttttgc tcttaaacga
     9961 attttcccaa cttccatgtc aagatcatcg taaatgataa gtaaatcgtc aatatccaaa
    10021 ccatagtaag ttaataaagc atgaactgct tttccacttt cattcataaa ggtcgttggt
    10081 ttaaccagat aaattttttc tccatttagg aaaaaggatg ctaggtcagc tttaaatatc
    10141 ttatcgtgtg taaaagtgac attctgtttc ttcgctagtt gatcaatcaa cataaaacca
    10201 acattgtgtt ttgtttcaaa atatttatcc cctggatttc ccaagcctac aagtaatttg
    10261 gtcatttatt tttcctttca aaagccaaaa gggttggaat ttttttccaa cctaattgac
    10321 accatttatt aatttttaga cattaaagcg gaattccatg atatcgccat cttgaacgat
    10381 atattctttt ccttcttcac gcaagcgtcc agcttctttt acggcctttt cagattcgta
    10441 tttcactaga tcctcatatg acatggttac tgcacgaata aagccttttt caaagtctga
    10501 gtggataata ccagctgctt gaggagcctt cataccacgt ttgaaagtcc aagcgcgaac
    10561 ttctttttca ccagctgtga agtaagttcc caatccaagc aagtggtaag ctgcacgcgt
    10621 caacttatct acacctgatt ctatcaaacc aatggcttca agaaactctt ttttatcttc
    10681 atcatccaat tcagaaattt cttcctcagc acgcgcagaa ataacgacta cttcagcatt
    10741 ttctgtcgct gcaaattcac gaatttgttt gacatagtcg atagagtcag gttctgaaac
    10801 cacatcctcg tccacattag ctacataaag aactggttta gtcgtcaaaa ggaaaagacc
    10861 tttgacaacc ttttgttcct catctgtaaa ttcaatggta cgagctgatt tcccgtcttc
    10921 taggactggt ttaatctttt gaagaacatt gaattctgct actgattctt tatctttttg
    10981 cgtacgtgcc atcttttcta cacgcgcata tcgtttattg actgattcta agtctgcaag
    11041 aatcaattct aggttaatgg tgtcaatatc tgcaagtgga tccacaaagg cgtcttcacg
    11101 tccttgctcg cgcatcacat tttcatcatc aaaagcacga actacgtgaa caatcgcatc
    11161 tacttcacga atattggcca agaatttatt ccctagccct tctccttttg aagctccttt
    11221 tacaatccct gcaatatccg taaattcaaa tgttgtggga actgtctttt taggagttat
    11281 catttcagtt agtttttgta ggcgttcatc tggaacttcc accattccaa catttggatc
    11341 aatagtcgca aatgggtagt ttgctgcctc tgctcctgct tttgtaattg cattaaatag
    11401 tgttgattta ccaacgtttg gcaaaccaac gatacctgct gtcaaagcca tatttctcat
    11461 tctccgtttt catttcaatc cctaatatta taacacaaaa agggataaag tgctaaccct
    11521 ctaactaagg gttctcagtc aataatttta ttcatttttc gctcaaaatc atatcgcccc
    11581 atcatgacaa catgctcaca attactgcat tttattttga tatctgctcc tacacgtgta
    11641 atttcccaac gattagcctt tttaccagtc gacttgattg tacaagcgtg tgattttttc
    11701 atctcaacaa aatttccaac ttgatacata ctactctcct tttctttttc gattatatca
    11761 taaaagaggc gagccaggct caacctcttt cacttaattt gtacgaactg gtgtaatgag
    11821 ctgcatgaag tcttcgtcag tatctgctgg cacaagagta aatggacgaa cagctgagat
    11881 aaagctaata gtcacctttt cgctatttaa agctttaaga gaatcaatca agtaagttgg
    11941 gttgaaacta atggtcaaat cttcaccagt aacctgatca gtatcgattt cttcgtttac
    12001 tttaccaact tctggagagt gaacatgggc gctaacaacc ccatccttaa tttcaagttt
    12061 cacagtacca ttttgagtcg cacttgataa aagacgggca cgctccattg actggcgtaa
    12121 gtttaccaca ttaaaagtaa tagtagtgtt aaagtctgtt ggaatcaagc gatctgtatc
    12181 aggatagttt ccttctagga gacgagtata gaagctaata ttttcgcttc taaagaggat
    12241 ttgattattg gcaaagaaaa tctctacagt ttcgatatca tctgtaaata ccgctgaaaa
    12301 ttcgcgtaga gaacggctag gaattacgac atcaaaatca tcactatttt tttcaagagt
    12361 caattttttc tggcttaggc gatgagagtc tgttgcaact gtttttaact ctttgtgttg
    12421 actcaatacg aagtggacac ctgttaaaat cggacgactc tcttgtgtac ttgcagcaaa
    12481 ggctgtttca ttaataattt tcttgagtaa ttttgtttca agtattaaag gagtgcttgc
    12541 tgaaatttct tggattcgtg gatattgttc gctatctttt ccttttaggg taatttctga
    12601 tttgccactg gttaaaacaa tttgattttg ttcaatttct ttaaaatcaa gagttacatc
    12661 aggtaaacta gatactacat tgataaagaa agaagcttca agaaggatcg aacctaaaga
    12721 agtaattaac aaaccagcat cttcattttt ttgagaaata aaattttcaa ttgaaatttg
    12781 accatttgaa ccaattaaag taataccttc attggtcacg tcaattttta ctgttgataa
    12841 aataggaatg gcatttttag aactaatagc tctcttagta gtatttaatg cttgtagaaa
    12901 taaattttta ttaattgaaa aatgaatcat ggattctcct ttatttattt ttagtattag
    12961 aaagataata gtaataatag agtctgtgaa atctgtggaa aacagccttt aaacaagtca
    13021 tatcaagttt tttagcttgt ttaaaaaatg tggataaaaa agataaaaaa ctaaaagtta
    13081 tccacaaatt atttgatttt ctttttgatt gattcaattt ctaaacgtaa attatcgtct
    13141 tgatcaatca aagattttat tttggcatgg gcatgaatga ctgtggtatg atcttttccc
    13201 ccaaattcct tcccaatttt tggaagacta ttatctgtta gttctctaga taaatacatg
    13261 gctacttgac gggccaaaac aatattttga aggcgtctac ttcccttcat ttctttgata
    13321 ctaacaccat aaaagttacc aacttcagtt tggattttat caattgggat gacgagcatt
    13381 tggctaacat cttgtttgcg ggctctaatg gcttctgcag caatatcaat agtgatatcc
    13441 ttgatttttt ttactctggc aattaaagtg atgtcgttga tggctccctc aagatctcga
    13501 acatttgaat caaattgccc agctaggtat tctagagtat cactttggaa attgtagcct
    13561 aaatgttccg ttttactttg taaaatggca atacgtgttt caaagtcagg gggtgtgata
    13621 gtttgtgtca atccccaact aaaacgcgtg acaagcctct cctcgagccc ttctagatgt
    13681 tttggactac gatcactcgt taggacaatc tgtttttgct tgtcatgaag ggcgttaaag
    13741 gtattgaaaa attcttcctg agttgcgact ttttttccgc tgagtgactg gatatcatcg
    13801 attaacaaaa gatcaagact acgataggtc tttttaaact tttccatttc cccaagtctt
    13861 aggtgatcaa gaaagtcatt aataaagctt tcggcaggga tatatttaac acgcgcatta
    13921 ggaatatttt ttagaatttc atttccaata gcgtttaata agtgagtctt accaaggcct
    13981 ggtcctccat agataaaaag agggttatag gtcagagcca aatcttcaga gacagctaaa
    14041 gcggctgata cagcccaaac atttccatcc ccttgaataa agttatcaaa ggtatacttt
    14101 tcttttaatc ccgtatctga ataaggaata gatactaact ttggactata gtcataaaga
    14161 gttaaatttg tagcttcttc aacttgtgag ctagtcgtat cttgaggttt ggtgaaaata
    14221 tagtggggag ttatttcagc gtcataaatt tcaaaaccag ctactacaat aatatctttt
    14281 agttgttttt cccagaccat ttccatttca gagcgaggta gaaatatagt ggcaacattt
    14341 tcctctacct tgatgagttc agcttgaata gcatagaaat catacatgga tcgagtcagt
    14401 ctttcttgtg caaattctaa tatacgattc caaaattgtt tttctttcaa tcctttctcc
    14461 tcctttacta tttaaaagtt taatactaga gatattttac catagatagc aagaattttc
    14521 cacaagctgt gaaaaataat ccacaatgtt actaaacttt atccacaggt tggggataaa
    14581 agaagaaatt attgatttat taagcttttt atcgaaaaac atagtggata accttgtgag
    14641 ataaaaaaat aaaagaacag ccttatttca ggctgttgat aattctacta tattcttctt
    14701 gatttgaaaa agaaataatg atttttccac tgtctttttt agatagttta atttctacat
    14761 ctaatccgag tagttttctt aactgttttt cttcattttg tatgaaataa ttagtttttt
    14821 gctgtttctt ttgttttttc tctgtcagaa gagcttctaa cttccttaca gaaatatctt
    14881 cttctataat ccgttgaaag aaatagtctt gttgttcctt atttaaccca actagggaac
    14941 gcgcatgggc ttgtgatagt ttgccatttt ctacttctga gagaatctgt tctggcaagg
    15001 aaagtaaacg aatggagttg ctgatatatg gacgagactt gcccatctta tctgcaattt
    15061 cagcatgggt gaatcctttc tctacgagag attcataggc gcgtgcttct tctattgggt
    15121 ttaaattttc tctctgtaaa ttttcaataa tggactggac catcatctct tggtctgaaa
    15181 tctgtttaac aacagctggg atagaccgta gaccagctaa aagtgaagcc cgatagcgtc
    15241 tctctcctgc aaggatttca taaccaataa caggagattg acgaacaata atcggttgaa
    15301 tgaccccatt ttctttgata gactgtgcta gttcatctag tttttctcta tcaaattctt
    15361 ttcggggttg atagggattt ttttgtatat ctgtgataga aatcatttca aatttttcca
    15421 tgattctaca ctaacacatc ttttctctta tgtaaagctt tctttacata gatgtcaatt
    15481 aagattctaa atcacctgaa ctcttgttaa gtttgataga ggtagtttct tctttcccgt
    15541 tacgatagta ggttatctta atggtgtctc cgatagaatg gttgtaaaga gcactttgta
    15601 agtctgttga tgaagcaatc tctttgtcat ctacttttgt aattacatcg tatttttcaa
    15661 ggtgaccatt ggcaggcata ttactttgta ccgaacgaac aattacacca gatgtaacat
    15721 tacttggaat attgagtctt ctgatgtcgc ttgtactcac attagataaa ttaaccatct
    15781 ggattcccaa agctggacgc gtcacttttc cgtttttttc taactgttca ataatattga
    15841 tagcatcatt tgcaggaatt gcgaaaccaa gaccttctac agatgttcct ccatttgtag
    15901 caattttact tgaggtaatt ccgataacct gcccttgaat attgatcagt gggccgccag
    15961 agttacctgg gttaatagca gtatcagttt ggatggcttt tgtagaaata gcttgtccat
    16021 cttccgattt taaggataca tttctattga gactggatac gataccttga gtgacagtat
    16081 ttgcatattc agaacctaac gggctaccga tggcaatagc agtttctcct acagttaact
    16141 tactagaatc accaaactca gctactgttg tcactttttc tgaagagatt ttgacgacag
    16201 caatatcaga gaaagtgtca gctccgacaa tttctccagg tactttagtc ccatctgaca
    16261 atcgaatatc tactttgctg gcgccattta taacgtgatt gttggtgacg atgtaagctt
    16321 ctttatcatt ctttttataa ataactccag atccttcact agagattcgc tgagaatctg
    16381 tgtcagtatc atcattgcca aatacgctat tttgtctgtt tgccgaataa gtaataacag
    16441 aaacaacagc atcttttact ttgttaacag cctgtgttgt tgaattttcg ttcttatagg
    16501 cagtttgtgt aatagtacta ttgttgttag agttgtttac actacttttt tgagttagtt
    16561 gagttattga aaaactaccc aaggctccac taaaaaagct aatgacgata acgactaata
    16621 attgaaacca ttttttgtaa aatgttttta gatgtttcat atttgcctcc atatgtttga
    16681 attactgaaa gtataaactg actagcttaa ttataactta aacacaaaag ttttacacaa
    16741 actgtggata actcttttga aactgtgatt ttcttaattg aaatctattt tttattttgt
    16801 gaataagatg tgaaaaaata gagaatatgt tagaatagag tcatgaaaat taaagttgta
    16861 acagttggga aactgaaaga aaagtattta aaagatggta tcgcagagta ttcaaaacga
    16921 atttctagat ttgctaagtt tgaaatgatt gagttatcag atgaaaaaac accagataag
    16981 gccagtgaat cagaaaatca aaagatttta gaaatagaag gtcagagaat tttatcaaaa
    17041 attgctgacc gtgatttcgt tattgtgtta gccattgaag ggaaaacttt cttctcagaa
    17101 gaattgagta agcagttaga agaaacttct ataaaaggat tttctactct tacttttatt
    17161 attgggggaa gtttaggatt gtcatcatct gtaaaaaata gagccaatct ttctgtcagt
    17221 tttggtcgcc taaccttgcc tcatcagtta atgagactag ttcttgttga acaaatctat
    17281 cgcgctttta cgattcagca gggattcccc taccataaat agaaaattga cttttaattg
    17341 aatttttggt agaataattg tgttaggtct catagctcag ctggatagag cattcgcctt
    17401 ctaagcgaac ggtcgcaggt tcgaatcctg ctgggatcaa tataatagca aagctgggaa
    17461 ttttcccggc ttttttctta aaaaagtaca ctttgggaga aaaaaatgac agttgagaga
    17521 attttatcta aaacgaaatt ccattttgta taatggtttt tgtaagttag cttacaagaa
    17581 aaaaacattt taggagattt tattatgaaa aacacagtta aattggaaca gtttgtagct
    17641 ttgaaggaaa aagacttaca aaagattaaa ggtggggaga tgaggctgtc aaaattcttc
    17701 cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg ggaaagagta atggatttat
    17761 ttggatttgg gacagttatt gttcattttt taattattag tcacaactac catttaattt
    17821 gtaaaggtca aataaataga aaagaattat tcgtttttgg tgcttataca ttactaacag
    17881 aaatagtatt tgattttccc ttatatattc tatatttaga tgggttaggg attgcaacat
    17941 ttttatttcc tttgggccta tattcctatt ttcgatggat aaaacagtat gagagggata
    18001 gaggactatt cctaagttta ctactatctc ttttatatga gagcactcat aactttctgt
    18061 ccgtaacttt ctcctctata acaggagata attttgtttt acaatatcat ttcccattct
    18121 ttttcgttgt gacggtgtta acctattttg ttacattaaa aatcatttac tatttccatt
    18181 tggaactagc ctattttgac aaggactacc tttatccttt cttgaaaaaa gtattttttg
    18241 ctttactatt gctacatatt gtatctttcg tttcagatat ggtaagtacg attaaacatt
    18301 tgaatagttt tggaagtatt ttgtcatcta ttgtctttat ctctctcctt ttgaccttct
    18361 ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat tgctttgaag cagaagaaat
    18421 ttgaacagaa acatttacag aattacacag atgaaattgt tggtctgtat aatgaaatcc
    18481 gtggttttcg acatgattat gctggaatgc ttgtcagcat gcagatggca attgacagtg
    18541 gtaatttaca ggaaattgac agaatttaca atgaagtttt agtcaaagca aatcataaat
    18601 tgcgttcaga taagtacact tactttgatt tgaacaacat agaagactca gctttacgaa
    18661 gtttggttgc tcagtcaatt gtctatgctc gaaataatgg tgtagagttt acactggaag
    18721 taaaagatac gattaccaag cttccaattg aactattgga tttggttcgt atcatgagcg
    18781 ttttattgaa taatgctgtc gaaggatcgg ctgatagcta taaaaagcag atggaagtag
    18841 cagttattaa gatggaaact gaaacagtta ttgtgattca gaattcatgt aaaatgacga
    18901 tgactccttc aggagatcta ttttccttag gattctccac taagggaaga aatcgcggag
    18961 tcggattaaa taatgtgaaa gaactactag ataagtacaa caatattatt ttagaaacag
    19021 agatggaagg cagtacattt agacaaatca ttagatttaa gagggaattt gaatgaaagt
    19081 tttaatttta gaagatgtta ttgaacatca agtgagacta gagagaatat tggatgaaat
    19141 ttcgaaagaa tcgaatattc caatatcata caagacaacg ggaaaagtcc gtgaatttga
    19201 agaatacatt gaaaatgatg aagtaaatca gctttatttc ctagatatcg atattcatgg
    19261 aattgagaaa aagggatttg aagtggctca gctcattcgt cattacaatc cttacgctat
    19321 tatcgtcttt atcactagtc gatcagagtt tgcgactcta acctataaat accaggtatc
    19381 agccctagat tttgttgata aggatatcaa tgatgagatg tttaagaaga gaattgagca
    19441 aaatatcttc tacacgaaga gtatgttact tgaaaatgaa gatgttgtag attatttcga
    19501 ctacaattac aagggaaatg atttaaaaat tccttaccat gatattttgt atattgaaac
    19561 aacaggggta tctcataaat tgcgcattat tggtaagaat tttgcaaaag agttttatgg
    19621 taccatgaca gatattcagg aaaaggacaa acatactcag cgattttatt ctcctcacaa
    19681 gtcatttttg gtaaatatag gcaatatcag agaaattgat cgaaaaaact tagaaattgt
    19741 tttctatgaa gaccatcgtt gtcctatttc aagattaaaa attagaaaat taaaagatat
    19801 tttagagaaa aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata
    19861 tctgctacag atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
    19921 aacacgggtt cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg
    19981 catgactgtt aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg
    20041 gaacacagct gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa
    20101 gtctgttatt tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc
    20161 aaaaagtgca tgagttagat agatgctact atattctaat tcagtggtat ttagattcag
    20221 ttgcataaat cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa
    20281 attttggatt tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc
    20341 tagatattca aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat
    20401 atattcaaat gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt
    20461 atagtgagta tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga
    20521 aattttatca aatggctgtt ccatcagtaa ttgtaccata gcattttcaa tagttcgctt
    20581 tgtttttaag cgtttgttac tttcttgcat atttcctcct tgtaaataaa ttagactata
    20641 tgtctaaaaa tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat
    20701 caaaatttta gacaatatgt ttaaaaaagg agaaactatg tttaaagaat ggaaagcaat
    20761 ttaaaaaaaa caacctttat tattgtcatg atcgggattt ctcttattcc agctctgtac
    20821 aatatcatat ttttgtcatc aatgtgggat ccatatgggc aattgtctga cttatctgtg
    20881 gcagttgtaa ataatgataa agaggcttcc tataatggta atactatggc aataggaaaa
    20941 gacatggtgt ccaatttaaa agaaaataaa accttggatt ttcattttgt agatgaagag
    21001 gaaggaaaga agggattgga agatggcgat tactatatgg tagtgacttt accaagtgat
    21061 ttatctaaaa aaacaactac attatccaat attcaatcga cagcagctta tcaatcattg
    21121 acaagtgagc aacaaactgg gataagtgat tctgtatctc aaaattcaac tgatagtatt
    21181 caatcggctc agtcaattgt agctttagta caaggtttac agggaagttt agaaaactta
    21241 caaaatcaat cttctaatct ttcgacttta aaaaatcaag ctaatcaagt attacctatt
    21301 acttctactt ctttgatagg attgtcaagt ggattaacag agatacaagg agctgttact
    21361 agcaaattag ttcctgccag tcagttgatt gcatcaggtg taaacgcata tactacaggt
    21421 gttgataaag tttctcaggg cgcaagtcaa ctaagtgaaa aaaatgccac cttgacaggt
    21481 agtttggata aactagtttc aggctcaaac accttgacac aaaaatcttc tagattgaca
    21541 gcaggagttg gttaattaca atcaggatct gggcaattag cagacaaatc cagtcagtta
    21601 ctttcaggtg cttctccatt agagaataga gctaataaat tggcagatgg atctgggaaa
    21661 ctagcagaag gtggaacaaa gttaacttct ggattggaag atttacagac aggacttgct
    21721 tctttaggac aaggactagg taatgctagt gatcaactca aatcagtatc aacagaatct
    21781 aaaaatgcag agattttgtc aaatccactc aatctttcaa aaacagacaa tgatcaagtt
    21841 cctgtaaatg gaatcgcaat agctccttat atgatatcag ttgctctttt tgttgcagca
    21901 atatcaacaa atataatatt tgcgaaattg ccttcaggac gtcatccaga gagccgttgg
    21961 ccttggttga aatctcgagc tgaaataaat ggtattatag ctgttttggc aggaattttg
    22021 gtatatggag gagttctatt ggtttaactg ctaatcatga gatgagaata tttattctca
    22081 tcatccaaac aagtttagta ttcatgtcta tggtgaccac tttagcaacg tggaatagcc
    22141 gtataggagc ttttttctca cttattttgc ttttactata gttagcatca agtgcaggta
    22201 cttatccact tgctttgaca aatgatttct ttagatctat taatccctgt ttaccaatga
    22261 gctattcagt ttcgggatta cgacaaacaa tctctatcaa caagtcattt tcctagctgt
    22321 catactagct ctatttactg gtttaggtat gctagcctat caacataaga aaatggaaga
    22381 agattaaaaa aatcgaccga ttaactggtc gattttttat gccttagatg actttcgtct
    22441 gtgattatag attccaaata gtaagagaga agtaaaggaa cagattgctc cagtaataaa
    22501 accattggga atgaaggaaa gtgtaatagt tcctttcccc ttgggaatgt caactttcat
    22561 aaatccagtt tgagcttgtt taatttctat tttcttacca tcttggtagg cagaccaacc
    22621 tttgtcataa ggaatggtga agaaaataga tgtatcttgt tggacatcat atgtagcaaa
    22681 aaccttgttt ttataagttg atactgtgac aggttgttct ttaatttttt gaattgcctc
    22741 ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat tcaaatgata cttgtgaatt
    22801 tccagggaaa ctaacattga tattgaaagt ttttttctct ttagtatatc ctagattaaa
    22861 gaaggagaag acattatcag ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac
    22921 cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa gagagataaa cttggctgtt
    22981 ttctggaact tcaatttgat actggattgc tgcatcttca tttgaagaac ttgtgatact
    23041 aatcaaatca ttagtatttt ctattttttc tgttttttca taaggtattg gagaaaaata
    23101 atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca aggtatgttc
    23161 attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa gagagtattg
    23221 attttcatat agggtaagat tatctttttg atagatatct ttaaagccat acttatcaat
    23281 aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa tactattatt
    23341 tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat ctaaagtaga
    23401 gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt tgaatttcat
    23461 actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat ttccaatata
    23521 tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag aagcaaatcc
    23581 ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt caaccagtat
    23641 aaataaagag attagaatgg caaatagatt cacagatata aactttttga taactgcaag
    23701 gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca aatctgttaa
    23761 aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta caagaaaaag
    23821 cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt ctgctgctgt
    23881 gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt ttggagtatg
    23941 catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta gaaatgcaaa
    24001 gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa aaaataaaat
    24061 ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat actttgttgt
    24121 gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac tttcagtttg
    24181 aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata gagtgggaag
    24241 agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat caagaacaga
    24301 tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa taagaaacaa
    24361 tactgtcata tatccaaaat aataattttg aataaataag attgacagac ttgtaaagta
    24421 caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta aaggaatcaa
    24481 gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac tcatcagagc
    24541 ataggaagta gataaggcta gttttaaagc ctgagggata gattgaaaca atttattcaa
    24601 actaaaaaag gttgacagac caatcaatcc aaattttaag agagttgtca gatagatagc
    24661 atctggcata ttcgttagat caaaaaagta aaccagaggc gcgagaaaac tacccaagta
    24721 ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt aaaacagact
    24781 actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt gatgaaagcc
    24841 atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata gatatactcc
    24901 agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg tttttaaaaa
    24961 tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca actgagtttt
    25021 gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct gcattttcta
    25081 ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat aagacaatga
    25141 tatggttagc caaagtttga ataaattcgt ggtcatggct ggcaaagatg attgattctt
    25201 taaagttttt caatccatca ttcaagcttg agatagattc caagtccaag tgatttgttg
    25261 gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc atgacacgaa
    25321 ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca gagaagagca
    25381 tacggccgag gaagccacgt aggaaagtat tgtcatcttc ttctttactt gcgaattgac
    25441 gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct tttggtaggt
    25501 aagattgact agttgtaact ccccacttga cagttccttc atagtcaata tctcccatga
    25561 ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct gtcttatcat
    25621 ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc tttacagtta
    25681 gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag ttgataaatg
    25741 gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc attttcttac
    25801 gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg aattcttgca
    25861 attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta gcagcaagct
    25921 cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt ccaaagtcaa
    25981 ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat actacgataa
    26041 ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg atatccaaac
    26101 cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct ttggcgagga
    26161 gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt aattcttctg
    26221 gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa cctccaagtt
    26281 cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag aaatcttcct
    26341 tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt cccatgataa
    26401 cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga acagagagac
    26461 gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca gctaaaattt
    26521 ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta tttccttctg
    26581 taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt gaaacatcag
    26641 atactgtaag caatattttt ctcctatatg tgtaatatat ttattctact agaaaataca
    26701 gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt atcctttaca
    26761 caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt cattaaaaaa
    26821 atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc attattttaa
    26881 caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt ctcaaaaatc
    26941 gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct gaccaacaag
    27001 ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga aatgtggctt
    27061 tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt caaagccaga
    27121 ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta gcacgtttgg
    27181 agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa agcattccga
    27241 caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc aaggctaatt
    27301 atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa attgttcgtt
    27361 cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt tatccagaaa
    27421 atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct aaatcactaa
    27481 ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta atgagtatgt
    27541 atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga aatatggttt
    27601 tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct gatatgaaag
    27661 aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta cttgaaatat
    27721 tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag gatatgggag
    27781 aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg ggtcaaaccc
    27841 tatctgaggt aaaaggggca atgggacttc attactttaa ttaagtttat tttacaagaa
    27901 actatcattt ctatctcgaa gaaaagatag ttttttattt acccctgtaa catttgacaa
    27961 atttttatag aatggtatga tagatacaat ataaaaagag tcaagctcaa aaagaaagaa
    28021 aagaggaaac ttcgaatgtc taattgggac actaaatttt tgaaaaaagg ttttaccttt
    28081 gatgatgtat tgcttattcc agctgaaagt catgtgttgc ctaacgatgc agatttaaca
    28141 actaaattgg cagataattt gactttaaat atcccaatta ttaccgctgc catggacaca
    28201 gttacagaga gtcaaatggc cattgctatt gctcgtgcag gtggtctcgg agttatccat
    28261 aaaaacatgt caattgctca acaagcagac gaggttcgta aggtaaaacg ttctgaaaat
    28321 ggagttatta ttgatccgtt cttcttgacg cctgaacata caattgctga agcagatgag
    28381 cttatgggtc gttaccgcat cagtggtgtt ccagttgttg aaacacttga aaatcgtaaa
    28441 ttggttggta ttttgacaaa ccgagatctt cgttttattt cagattataa tcaaccaatt
    28501 tcaaaccata tgactagtga aaatcttgtt actgctcctg tgggtacgga tcttgcaacg
    28561 gctgagagta ttcttcaaga gcatcgtatt gaaaaacttc cgttggtcga tgaagaaggc
    28621 agtctttctg gtttgatcac tatcaaagat attgaaaaag ttattgagtt tccaaatgcg
    28681 gctaaagatg aatttggtcg tcttctagtt gcaggtgcag taggtgttac ttcagataca
    28741 tttgaacgtg cagaggctct ttttgaggca ggagcggatg cgattgttat tgatactgca
    28801 catggtcatt ctgcaggtgt cttgcgtaaa attgccgaga ttcgtgctca tttcccagat
    28861 cggactttga ttgctggaaa tattgctact gctgaaggtg cacgtgccct ttatgaagcg
    28921 ggtgtagacg ttgttaaggt tggtattgga ccaggttcta tctgtactac tcgtgtgatt
    28981 gctggtgttg gtgttccgca agtaacagct atctacgatg ctgcagctgt tgcgcgcgaa
    29041 tatggtaaaa cgattattgc tgacggtggg atcaagtatt ctggagatat tgtaaaagca
    29101 cttgctgcag gtggaaatgc tgttatgctt ggatctatgt ttgctggaac tgatgaagct
    29161 ccaggcgaaa ctgaaatctt ccaaggacgt aaattcaaga cttaccgtgg tatgggatca
    29221 attgctgcta tgaagaaagg ttcaagcgac cgttatttcc aaggttctat caatgaagca
    29281 aacaagctcg ttccagaagg aattgaaggt cgtgttgctt ataaaggagc ggcagctgat
    29341 attgttttcc aaatgattgg tggtattcgc tctggtatgg gttactgtgg tgcagctaac
    29401 cttaaagaac tacacgataa tgctcaattt attgaaatgt ctggtgctgg tttgaaagaa
    29461 agccatcctc atgatgtgca aattactaat gaggcaccaa attattctat gtaaaaaaca
    29521 atgaaaagaa ctccagtgaa aacaggagtt cttttacaat gttgtcaatt tccatttaca
    29581 gcagctttac catcctgaat agtgaagata cttagatttt ctggtagatt ttgaagatgg
    29641 tctaagcttg ttgttgtgat aaaggtttgg attgattgag aaatcgtttc taataatttt
    29701 aattgtctag tgttgtcaag ttcactcatc acatcgtcaa gcagtaatat aggagattct
    29761 gtggtaatgc tttccattaa ttcgatttct gctaatttta tcgagaggac gagactacga
    29821 tgttgacctt ggcttccgaa actagcatcc atcccattta tataaaaaga aatgtcatct
    29881 cgatgaggac cgacaccagt attcttttta aataaatctc tggatttact tttttctaaa
    29941 gcaattttga aagattcgga taagttttgt ttgtcagtta tattgacaga agattgatag
    30001 gatattgaca actcttcgat ctgattagag agttcaaaat gtttcttacg cccaaatgat
    30061 tctagttttt ttatgaaatc taagcggtga ttcattacac gacatccata atcaactagc
    30121 tgatcatcta acacagaaag gaatgtttca tctatttttt gatctgattt taggtaagtg
    30181 tttctttgct ttaggatgtg gttataattg gttaagtcag ataagtagat tggcttaatt
    30241 tgcccaagtt ccatatcgat gaattttcgt cgaatcgaag gtgctccttt aattagttgt
    30301 aaatcttcag gagcaaataa gacaacattc atgtgtccta cataatctga aaggcgtgcc
    30361 tgttttaagt gattaacttt tgttacacgg cctttttgtg ttagttcgat ttctagggga
    30421 atggatccag tttttttctg aacgagacct gaaagatgaa gttgttcctc atcaaaatga
    30481 atgagatttt tatctgttcg agttcgatga ctacgcgtta aggctaaaaa atagatagcc
    30541 tctaacatgt ttgtttttcc ttgtgcatta cgtcccaaaa agacattcaa tttaggatta
    30601 aagtctattt tcgtttcttt gtaattacga aaagtcttga gagatagatg ttgtagccac
    30661 atgattatct accagggaat cgtggagctt gttggctttt aggtgatgaa gcaggtttcg
    30721 atttgtcttt tttaactccc ttattcatct ttttgacaag tttagcgatc cgttcttttt
    30781 caactttatc agcttggtat tcatcttgtt cttcagaagt aggttgtgtc aacaagatgt
    30841 caatgttcat gtcagggatg tcaactttat cgccaatacg aagttttttt ccacgacgac
    30901 tctctaattc cctattaaag taaacagaat gttcagagag aaatgattta atagctcctc
    30961 cgctatgtgt aattccaagt tctttgagta gtgcttggag ggtaataaat tcttcaaata
    31021 atttgtattc cataattcac ctcaatcttt ggtattatac catattttcc taaaaatagt
    31081 gagagagaca gcgagaaatg taagcgattt ttatttcaaa agtgttacag ggaacaagaa
    31141 aatttcaggt tttcgtgata taatagaagt ctgtatataa ggaggtaaat catggagtta
    31201 gtgcatggaa tttcaacaca ttttatccaa tcaaaaaagt ttaaaacaaa caaaattacc
    31261 gtgcgtttta ccgctccatt atcccttgat acgattgcag gtcacatgtt gagtgcaagt
    31321 atgctagaga ctgctaatca gatgtacccc acttctcaag atttgaggag acacttggcc
    31381 agtctatacg gtacagatat gtcaaccaat tgtttcagaa gagggcaaag ccacattata
    31441 gaattgacat ttacctatgt tcgtgatgag tttttaagta ggaaaaacgt gctaacctct
    31501 cagattttgg aacttgtaaa agaaactctt ttttcacccg tagtagttga taatgggttt
    31561 gatccggcct tatttgaaat tgagaaaaaa caattgctag caagtttagc agctgatatg
    31621 gatgattctt tttattttgc acataaagaa ttggataaat tgttttttca tgatgaacgt
    31681 cttcaattgg aatatagtga tttacgaaat cgtattttag ctgaaactcc acaaagttct
    31741 tactcttgtt tccaagaatt tttagccaat gatcgaatag atttcttttt cctaggtgat
    31801 tttaatgagg ttgaaattca aaatgtatta gaatcatttg gctttaaagg tcgaaaagga
    31861 gatgtgaagg ttcagtattg tcaaccttat tctaatatcc ttcaggaagg tatggttcgg
    31921 aaaaatgtgg gacaatccat tttggaatta ggttatcatt accgttctaa atatggtgat
    31981 gaacaacatt tacccatgat tgtaatgaat ggtttacttg gtggatttgc tcactctaag
    32041 ctctttacaa atgtccgtga aaatgctgga ttagcttata ccatttcaag tgagcttgat
    32101 ttatttagtg gattcttgag gatgtatgct ggtatcaatc gagaaaatcg taaccaggct
    32161 cgtaaaatga tgaataatca actgcttgat ttaaaaaaag gttattttac agagtttgag
    32221 ttaaatcaga ccaaggaaat gattcgttgg tcgttgttac tttctcaaga taatcaatct
    32281 tcattgattg aacgtgctta tcaaaatgcc ttatttggaa aatcttcagc agactttaaa
    32341 agttggattg caaagcttga acaaattgac aaagatgcta tttgtagagt agctaataat
    32401 gtgaaactac aagcgattta ctttatggaa ggaatagaat gacaaaggtt gtttttgaag
    32461 aaaaatacta tccagctgta aaagaaatgg tttatcgaac tcgtttggcc aacggattga
    32521 cagttgctct tttgcctaaa aaggaattta aagaggttta cggaagtgtc actgtacagt
    32581 ttggttcggt agatacgttt gtcacagaag ttgacggaga tgtaaaacaa tatcctggag
    32641 gaattgctca ttttcttgaa cataaattat ttgagagaga agattctagt gatttgatgt
    32701 cggcttttac gagtctaggt gcagatagta atgcctttac aagctttaca aaaacaaact
    32761 atcttttttc agcaacggat tattttttag aaaatttaga tttacttgat gaattggtaa
    32821 catcagcaca ctttactgaa gcttccattt tgacagagca ggatattatt cagcaagaac
    32881 gagaaatgta ccaagatgat ccagattcgt gtttattctt ttcaacttta gcgaatttgt
    32941 atcctggtac acctttagca actgatatag ttggaagtga ggagtccatt tcccaaatca
    33001 atctaactaa tttgcaagaa aattttacaa agttttacaa acctgtaaac atgtctctgt
    33061 ttttagttgg taattttgat gtggagcgag tacaggacta ttttgaaagc aaagaactga
    33121 aagattcaga ttttcaggaa gtagcaagag aaaagttgtt tttacagcct gtaaagccaa
    33181 cagatagtat gagaatggaa gtatcttctc ccaaactagc gattggagtt agaggtaagc
    33241 gagaagtttc tgaagcggat tgctatcgac atcatatttt attaaaatta ttgtttgcaa
    33301 tgatgtttgg ttggacttcg gatcgttttc aaaaatgtta tgaatcaggt aaaattgatg
    33361 catccttatc tctggaagtt gaagtaacaa gtcgctttca ttttgtcatg ttgacaatgg
    33421 atacgaaaga gccagttgct ttgtctcatc aatttaggaa ggctattcgt aattttacaa
    33481 aggatttaga tattacagag gaacatttag atattatcaa aagagagatg tttggcgaat
    33541 ttttcagtag catgaactct cttgaattta ttgcaacgca atatgatgct tttgaaaatg
    33601 gtgagacaat ttttgatttg ccgaaaattt tacaggaaat tactttagag gatgtccttg
    33661 atgctggaca tcatttaata gatgatggtg acatagttga ttttacaata ttcccatcgt
    33721 agtaacctat tataatagac actagaaaga agggatgaca agtatgagaa aaaaaacaat
    33781 tggagaggtt ttacgattag ctagaatcaa tcagggattg agtttagatg aattgcagaa
    33841 aaagacagaa atccagttag atatgttgga agcaatggaa gcagacgatt tcgatcaact
    33901 tccaagtcct ttttacacgc gttctttctt gaaaaaatat gcatgggctg ttgagttaga
    33961 tgaccaaatt gttttggatg cttatgattc tgggagtatg attacttatg aggaagtaga
    34021 tgttgatgaa gatgagttga caggtcgtag acgttcaagt aagaaaaaga agaaaaaaac
    34081 atcattttta cctttatttt attttatcct ttttgcttta tcgattttaa tttttgtgac
    34141 ttattatgtt tggaactata ttcaaactca accagaggag ccttctcttt ctaattacag
    34201 tgtggttcaa tcaacaagtt caactagctc tgttccccac tcctcaagta gtagttcttc
    34261 tagtatagaa tcagctataa gtgtatcagg cgaaggaaat catgtagaaa tcgcttataa
    34321 gacaagtaag gaaacagtta aattgcaatt ggcagtttca gatgttacaa gttgggtcag
    34381 tgtttcagaa agcgaacttg agggcggtgt aaccttatcg ccaaagaaga aaagtgcaga
    34441 agcaacagtt gcaactaaaa gtcctgtaac aattacgtta ggtgttgtaa aaggtgttga
    34501 tttgacagta gataatcaga ctgttgattt atcgaaatta acagctcaga ctggacaaat
    34561 cactgtaacc tttactaaaa attaaggaaa aacgaatgaa aaaagaacaa attcccaatc
    34621 tcttaacaat aggtcgaatt ctctttatac ctatttttat ctttatttta acgataggaa
    34681 attcgataga gagtcatata gttgcagcta ttatctttgc tgttgccagt attaccgact
    34741 atttagatgg atatttagct cgtaaatgga atgtggtcag taattttggt aaatttgcag
    34801 atcctatggc ggataagtta ctagttatgt cggcttttat tatgttgatt gagttaggta
    34861 tggctccggc ttggattgtt gcagtgatta tctgtcgtga gttagctgtg acaggtttaa
    34921 ggcttttatt ggttgaaact ggtggaacaa ttttagcagc agcaatgcct ggaaaaatta
    34981 aaacttttag tcagatgttt gctattattt tcttgctatt acattggact ttgcttggtc
    35041 aagttctact ttatgtagcc ttatttttca ctatctactc tggctatgac tatttcaagg
    35101 gtagtgccta tgtatttaaa gggacatttg gttcgaaatg aaatcaataa ttgatgtaaa
    35161 aaatctttct tttcgctata aagaaaatca gaactactac gatgtgaagg atattacgtt
    35221 tcacgtgaaa cgtggagaat ggctttcgat tgtagggcat aatggtagtg gtaaatcaac
    35281 tacggttcga ttaattgatg gcttactgga agcagaatcc ggagagattg taattgatgg
    35341 ccaacgtttg actgaggaaa atgtttggaa tatacgtcgt caaatcggta tggtttttca
    35401 aaatccagac aatcaatttg ttggagcgac tgttgaagat gatgttgctt ttggtttgga
    35461 aaatcaggga ctttctcgtc aagaaatgaa aaagagagtg gaagaagctc tggctttagt
    35521 tggcatgttg gactttaaaa agagagagcc agcgcgtcta tcaggtggtc aaaagcaacg
    35581 tgtggccatt gcaggtgttg tagccctaag accagctatt ttaatcttag atgaagcaac
    35641 gagtatgttg gatcctgagg ggcgtagaga acttattggg acagtaaaag gaattcgaaa
    35701 agactatgat atgacggtca tttctattac ccatgatttg gaagaagtcg ccatgagtga
    35761 tcgcgtattg gtcatgaaaa aaggggaaat tgaatcaact agtagtccaa gggagctttt
    35821 ctctcgaaat gatttagatc aaattggatt agacgatcct tttgctaatc aattaaaaaa
    35881 atctttgagc cagaatggct atgatttacc tgaaaattat ttgacagaaa gtgagctaga
    35941 ggataagcta tgggaattgc tctagaaaat gtgaatttta catatcaaga aggtactccc
    36001 ttagcttcag cagctttgtc ggatgtttct ttgacgattg aagatggctc ttatacagct
    36061 ttaattgggc acacaggtag tggtaaatca actattttac aactcttaaa tggtttattg
    36121 gtgccaagtc aagggagtgt gagggttttt gataccttaa tcacctcgac ttctaaaaat
    36181 aaagatattc gtcaaattag aaaacaggtt ggcttggtat ttcagtttgc tgaaaatcag
    36241 atttttgaag aaacggtttt gaaggacgtt gcttttggac cgcaaaattt tggagtttct
    36301 gaagaagatg ctgtgaagac tgcgcgtgag aaactggctc tggttggaat tgatgaatca
    36361 ctttttgatc gtagtccgtt tgagctgtca gggggacaaa tgagacgtgt tgccattgca
    36421 ggcatacttg ccatggagcc agctatatta gtcttagatg agccaacagc tggtctagat
    36481 cctctaggga gaaaagagtt gatgaccctg ttcaaaaaac tccaccagtc agggatgacc
    36541 atcgtcttgg taacgcattt gatggatgat gttgctgaat atgcaaatca agtctatgta
    36601 atggaaaagg gacgtttagt aaaggggggc aaaccaagtg atgtctttca agacgttgtt
    36661 tttatggaag aagttcagtt gggagtacct aaaattacgg ccttttgtaa acgattggct
    36721 gatagaggcg tgtcatttaa acgattaccg attaagatag aggagttcaa ggagtcgcta
    36781 aatggatagt atgattttgg ggcgttatat cccaggggat tcgattgttc accgattgga
    36841 tccacgtagc aaattgcttg ctatgatgct actgattttg attgtgtttt gggctaataa
    36901 ccccttgacg aatctgattc tttttatagc gacagggata tttattgcct tgtcaggagt
    36961 atctctttca ttttttattc agggcttgaa gtctatgttt ttcttgattg ccttcacaac
    37021 tatttttcaa ctatttttca tttctaatgg gaatgtttta tttgagtttt cgtttgtgag
    37081 aatcacggat tatgctttgc aacaagctgg gattattttt tgtcgctttg tattgattat
    37141 tttcttttca actttgttaa ccttaacaac catgccttta agtttggcat cagctgtcga
    37201 agctttatta gcacctttaa agcgtgtgaa agttccagtt catgaaattg gattgatgct
    37261 gtctatgagt ttgcgttttg tcccaacctt gatggatgat acgactcgga ttatgaatgc
    37321 acagaaagct cgtggagtgg attttggaga aggaagcatc gttcaaaaag taaaggcgat
    37381 gattcccatt ttgattcctc tttttgcgac aagtttaaaa cgtgcagatt ccttggctat
    37441 cgctatggaa gcgcgtggct atcagggtgg aaaaggcaga agtcaatacc gacaattgaa
    37501 atggactcta aaggatacgc tgaccattct tgttattctc gtacttggtt gttgtttatt
    37561 tttcttaaaa tcttagtagc tttcaggaat tgataaaaag ttactgtaac agtttttgat
    37621 ataaaggtag ggatatgaac cgttttaaaa aatcaaaata tgtcattatt gtttttgtca
    37681 ctgttctgct tgtgtcagct ctcttagcga cgacttattc aagtacaatt gtgacaaaat
    37741 taggagatgg aatctcattg gttgatagag ttgtacaaaa accttttcag tggtttgatt
    37801 ctgtcaaatc agatttggct catttgacac gaacatataa tgaaaatgaa agtttgaaga
    37861 aacagcttta ccaattagaa gttaaatcaa atgaggtgga aagtttaaag acagaaaatg
    37921 aacaactgcg ccaattgctt gatatgaagt ctaaattgca agccacaaag actttagcag
    37981 cagatgttat tatgcgttct ccggtatctt ggaagcagga gttgacctta gatgcaggta
    38041 gatcaaaagg tgcttctgag aacatgttag ctattgcaaa tggtggcttg attgggagtg
    38101 tttcaaaagt agaggagaac tctactatag tcaaccttct gacaaatacg gaaaatgctg
    38161 ataagatttc tgttaaaatt caacatggct ctactacaat ttatggaatt attattggct
    38221 atgacaagga aaatgacgtt cttaaaatta gccaattaaa tagtaatagc gatattagtg
    38281 cgggagataa ggtgactact ggtggattag gaaactttaa cgttgctgat attcctgttg
    38341 gtgaagtggt tgccacaacg catagtacag actatttgac acgagaagta actgttaaat
    38401 tgagtgcaga tactcataat gtagatgtga tagaattagt ggggaattca taatgagaca
    38461 gttgaagcga gttggagtat ttttattgct tcctttcttt gttctaattg acgcccatat
    38521 tagccagctt ctgggctcat ttttccccca tgtacatttg gctagtcatt ttctttttct
    38581 atttctctta tttgagacga tagaagtatc agagtatctc tacctagtct attgttttgt
    38641 tataggcttg gtttatgatg tttacttttt ccatctaata gggattacaa ctctcttatt
    38701 tatcttattg ggagccttcc ttcataaatt gaatagtgtt attttgttga atcgttggac
    38761 aagaatgcta gctatgattg tgctgacatt cctgtttgaa atgggtagtt atcttttggc
    38821 ttttatggta gggttgacag tagatagcat gtcgattttt atagtctata gcttggtacc
    38881 gacgatgatt ttaaattttt tatggattac tgtttttcaa tttatttttg aaaaatatta
    38941 tctataagaa cgacatataa atgtaacaaa ggcgtaatat ttattaggcc tttttttggt
    39001 atactagtat tgtctttaaa agaaggagta tctacgtaat atgaagaaaa aaatcttagc
    39061 gtcactttta ttaagtacag taatggtttc tcaagtagct gttttaacaa ctgcgcatgc
    39121 agaaacgact gatgacaaaa ttgctgctca agataataaa attagtaact taacagcaca
    39181 acaacaagaa gcccaaaaac aagttgacca aattcaggag caagtatcag ctattcaagc
    39241 tgagcagtct aacttgcaag ctgaaaatga tagattacaa gcagaatcta agaaactcga
    39301 gggtgagatt acagaacttt ctaaaaacat tgtttctcgt aaccaatcgt tggaaaaaca
    39361 agctcgtagt gctcaaacaa atggagccgt aactagctat atcaatacca ttgtaaactc
    39421 aaaatcaatt acagaagcta tttcacgtgt tgctgcaatg agtgaaatcg tatctgcaaa
    39481 caacaaaatg ttagaacaac aaaaggcaga taaaaaagct atttctgaaa aacaagtagc
    39541 aaataatgat gctatcaata ctgtaattgc taatcaacaa aaattggctg atgatgctca
    39601 agcattgact acgaaacagg cagaactaaa agctgctgaa ttaagtcttg ctgctgagaa
    39661 agcgacagct gaaggggaaa aagcaagtct attagagcaa aaagcagcag ctgaggcaga
    39721 ggctcgtgca gctgcggtag cagaagcagc ttataaagaa aaacgagcta gccaacaaca
    39781 atcagtactt gcttcagcaa acactaactt aacagctcaa gtgcaagcag tatctgaatc
    39841 tgcagcagca cctgtccgtg caaaagttcg tccaacatac agtacaaacg cttcaagtta
    39901 tccaattgga gaatgtacat ggggagtaaa aacattggca ccttgggctg gagactactg
    39961 gggtaatgga gcacagtggg ctacaagtgc agcagcagca ggtttccgta caggttcaac
    40021 acctcaagtt ggagcaattg catgttggaa tgatggtgga tatggtcacg tagcggttgt
    40081 tacagctgtt gaatcaacaa cacgtatcca agtatcagaa tcaaattatg caggtaatcg
    40141 tacaattgga aatcaccgtg gatggttcaa tccaacaaca acttctgaag gttttgttac
    40201 atatatttat gcagattaat ttacagaggg actcgaatag agccctcttt tcaggtttta
    40261 ccgtgacaat ccctattaaa aattatatca aaatagcttg aaaatattgg aaaagtatgg
    40321 tagaatgaaa attgtcgtgt gaacgataat actcattctt gatgaattgt gaagcagttg
    40381 cccttgggtc gttttgcgag ttgaagtcaa gaagaggaaa aaaacaaaaa ggagaaatac
    40441 tcatggcagt aatttcaatg aaacaacttc ttgaggctgg tgtacacttt ggtcaccaaa
    40501 ctcgtcgctg gaatcctaag atggctaagt acatctttac tgaacgtaac ggaatccacg
    40561 ttatcgactt gcaacaaact gtaaaatacg ctgaccaagc atacgacttc atgcgtgatg
    40621 cagcagctaa cgatgcagtt gtattgttcg ttggtactaa gaaacaagca gctgatgcag
    40681 ttgctgaaga agcagtacgt tcaggtcaat acttcatcaa ccaccgttgg ttgggtggaa
    40741 ctcttacaaa ctggggaaca atccaaaaac gtatcgctcg tttgaaagaa attaaacgta
    40801 tggaagaaga tggaactttc gaagttcttc ctaagaaaga agttgcactt cttaacaaac
    40861 aacgtgcgcg tcttgaaaaa ttcttgggtg gtatcgaaga tatgcctcgt atcccagatg
    40921 tgatgtacgt agttgaccca cataaagagc aaatcgctgt taaagaagct aaaaaattgg
    40981 gaatcccagt tgtagcgatg gttgacacca atactgatcc agatgatatc gatgtaatca
    41041 tcccagctaa cgatgacgct atccgtgctg ttaaattgat cacagctaaa ttggctgacg
    41101 ctattatcga aggacatcaa ggtgaggatg cagtagcagt tgaagcagaa tttgcagctt
    41161 cagaaactca agcagattca attgaagaaa tcgttgaagt tgtagaaggt gacaacgctt
    41221 aatttataca aatagtaatt acctaggagg gcggggctta gcccggctct cctattttca
    41281 aaaaatatag gagaattaaa atggcagaaa ttacagctaa acttgtaaaa gagttgcgtg
    41341 aaaaatctgg tgccggtgtt atggacgcta aaaaagcgct tgtagaaaca gacggtgaca
    41401 tcgaaaaagc gattgaattg cttcgtgaaa aaggtatggc taaggcagct aagaaagctg
    41461 accgtgttgc tgcagaaggt ttgactggtg tttatgttaa cggtaatgtt gcagcagtta
    41521 ttgaagtaaa cgctgaaact gacttcgttg caaaaaacgc tcaattcgtt gaattggtaa
    41581 atactacagc taaagtcatt gctgaaggaa aacctgctaa caatgaagaa gctcttgctt
    41641 tgataatgcc ttcaggtgaa actcttgaag ctgcatacgt atctgcaaca gcaactatcg
    41701 gagagaaaat ctcattccgt cgctttgcat tgattgaaaa aacagacgca caacactttg
    41761 gagcatacca acataacggt ggacgtatcg gtgttatttc agttgttgaa gatggagacg
    41821 aagcacttgc taaacaattg tcaatgcaca tcgcagcgat gaaaccaaca gttctttctt
    41881 acaaagaatt ggatgagcaa ttcgttaaag atgagttggc acaattgaat cacgttatcg
    41941 accaagacaa cgaaagccgt gcaatggtta ataaaccagc tcttccacac ttgaagtatg
    42001 gatcaaaagc tcaattaact gatgatgtta ttgctcaagc tgaagctgac atcaaagctg
    42061 aattggctgc agaaggcaaa ccagaaaaaa tctgggacaa aattattcca ggtaaaatgg
    42121 atcgcttcat gcttgataac actaaagttg accaagctta cacacttctt gcacaagttt
    42181 acatcatgga tgacagcaag acagttgaag cataccttga atcagttaac gcttcggtag
    42241 ttgagtttgc tcgctttgaa gttggtgaag gtatcgagaa agctgcaaac gacttcgaag
    42301 ctgaagttgc agctacaatg gcagcagcct tgaataacta ataatagaaa ggaagcaaat
    42361 tgcttccttt tttgtatagg gcttagattt ttcctgaaat tgttttttcc ccagtctcac
    42421 tcgattagaa taattaaaac aaaaagccct ataataaggg ctaagtgcat ttaggagact
    42481 atacttcaaa ttcatagtaa gcgcgtcata acaaggtatc tatcctaatt ccccaacttc
    42541 cagtatacta gataaaaaat aattatcgga ggaaaggtat tgtactatga taattcaact
    42601 aagtgattta ggtcaagttc accttgtttg tggcaagaca gatatgaggt agggaataga
    42661 ctcattagcc tatgtagtta aaacccactt tgaattggat tctttctccg gtcaagtctt
    42721 tctcttttgt ggtggacgta aagaccgctt taaagccctt tactgggatg gtcaaggatt
    42781 ttggctacta tataaacgct ttgagaacgg aaaactgact tggctaagta cagaaaagga
    42841 tgtcaaagct ctcgcacctg aacaagtaga ttggcttatg aagggctttt ctatcactcc
    42901 aaaaatatag tagattgaaa ctagaatagt acacctctgc ttctaaaaca ttgttagaaa
    42961 tcgatttgat tgtcctgttc ttatttcatt ttactataaa tccatcagaa agttgtgatt
    43021 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtcca
    43081 tctccgatta acgatggact ttatcacctc cttctccagt ccttgtatga catcttccaa
    43141 agttcgaaag gctttattct taaatccacg tttacgaa
//
LOCUS       DBERAE010000013        40376 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.13, whole genome shotgun sequence.
ACCESSION   DBERAE010000013 DBERAE010000000
VERSION     DBERAE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.13"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            184..414
                     /gene="blpU"
                     /locus_tag="ACL70N_000871"
     CDS             184..414
                     /gene="blpU"
                     /locus_tag="ACL70N_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGS0589693.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            417..542
                     /locus_tag="ACL70N_000872"
     CDS             417..542
                     /locus_tag="ACL70N_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS0589694.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            1129..3282
                     /gene="comA"
                     /locus_tag="ACL70N_000873"
     CDS             1129..3282
                     /gene="comA"
                     /locus_tag="ACL70N_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGS0589695.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNSLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3295..4644
                     /gene="comB"
                     /locus_tag="ACL70N_000874"
     CDS             3295..4644
                     /gene="comB"
                     /locus_tag="ACL70N_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGS0589696.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4814..5521
                     /gene="purC"
                     /locus_tag="ACL70N_000875"
     CDS             4814..5521
                     /gene="purC"
                     /locus_tag="ACL70N_000875"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS0589697.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIVG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5523..5666
                     /locus_tag="ACL70N_000876"
     CDS             5523..5666
                     /locus_tag="ACL70N_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS0589698.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5723..9448
                     /locus_tag="ACL70N_000877"
     CDS             5723..9448
                     /locus_tag="ACL70N_000877"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGS0589699.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9541..10983
                     /gene="purF"
                     /locus_tag="ACL70N_000878"
     CDS             9541..10983
                     /gene="purF"
                     /locus_tag="ACL70N_000878"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGS0589700.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11020..12042
                     /gene="purM"
                     /locus_tag="ACL70N_000879"
     CDS             11020..12042
                     /gene="purM"
                     /locus_tag="ACL70N_000879"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGS0589701.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12039..12584
                     /gene="purN"
                     /locus_tag="ACL70N_000880"
     CDS             12039..12584
                     /gene="purN"
                     /locus_tag="ACL70N_000880"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGS0589702.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12668..13177
                     /locus_tag="ACL70N_000881"
     CDS             12668..13177
                     /locus_tag="ACL70N_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS0589703.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13202..14749
                     /gene="purH"
                     /locus_tag="ACL70N_000882"
     CDS             13202..14749
                     /gene="purH"
                     /locus_tag="ACL70N_000882"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGS0589704.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14871..16133
                     /gene="purD"
                     /locus_tag="ACL70N_000883"
     CDS             14871..16133
                     /gene="purD"
                     /locus_tag="ACL70N_000883"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGS0589705.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKTFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16324..16815
                     /gene="purE"
                     /locus_tag="ACL70N_000884"
     CDS             16324..16815
                     /gene="purE"
                     /locus_tag="ACL70N_000884"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGS0589706.1"
                     /translation="MTKPIISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTP
                     DLMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSN
                     ELI"
     gene            16802..17893
                     /gene="purK"
                     /locus_tag="ACL70N_000885"
     CDS             16802..17893
                     /gene="purK"
                     /locus_tag="ACL70N_000885"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGS0589707.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17903..18130
                     /locus_tag="ACL70N_000886"
     CDS             17903..18130
                     /locus_tag="ACL70N_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS0589708.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            18193..19491
                     /gene="purB"
                     /locus_tag="ACL70N_000887"
     CDS             18193..19491
                     /gene="purB"
                     /locus_tag="ACL70N_000887"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGS0589709.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19546..23484)
                     /gene="strH"
                     /locus_tag="ACL70N_000888"
     CDS             complement(19546..23484)
                     /gene="strH"
                     /locus_tag="ACL70N_000888"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGS0589710.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKADVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKIISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEDIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23797..24513)
                     /locus_tag="ACL70N_000889"
     CDS             complement(23797..24513)
                     /locus_tag="ACL70N_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0589711.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIEFISCDRDH"
     gene            24861..26648
                     /locus_tag="ACL70N_000890"
     CDS             24861..26648
                     /locus_tag="ACL70N_000890"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGS0589712.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26645..27121
                     /locus_tag="ACL70N_000891"
     CDS             26645..27121
                     /locus_tag="ACL70N_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0589713.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27149..28054
                     /locus_tag="ACL70N_000892"
     CDS             27149..28054
                     /locus_tag="ACL70N_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0589714.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28041..28856
                     /locus_tag="ACL70N_000893"
     CDS             28041..28856
                     /locus_tag="ACL70N_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0589715.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28863..29267
                     /locus_tag="ACL70N_000894"
     CDS             28863..29267
                     /locus_tag="ACL70N_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0589716.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29566..30726
                     /locus_tag="ACL70N_000895"
     CDS             29566..30726
                     /locus_tag="ACL70N_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS0589717.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEY"
     gene            30848..31885
                     /locus_tag="ACL70N_000896"
     CDS             30848..31885
                     /locus_tag="ACL70N_000896"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGS0589718.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32092..32946
                     /locus_tag="ACL70N_000897"
     CDS             32092..32946
                     /locus_tag="ACL70N_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0589719.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33096..33353
                     /locus_tag="ACL70N_000898"
     CDS             33096..33353
                     /locus_tag="ACL70N_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGS0589720.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33521..33757)
                     /locus_tag="ACL70N_000899"
     CDS             complement(33521..33757)
                     /locus_tag="ACL70N_000899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589721.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLMWFEEIFEEYKFLHNKTHITKVLMN"
     gene            complement(33811..34044)
                     /locus_tag="ACL70N_000900"
     CDS             complement(33811..34044)
                     /locus_tag="ACL70N_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS0589722.1"
                     /translation="MDVREAHEFQAGHAPGAKNLPLSTLEQGYKELKPDHEYYVICQG
                     GVRSASTCQFLSSQGLTVTNVEGGMNTWPGQVE"
     gene            complement(34097..34279)
                     /locus_tag="ACL70N_000901"
                     /pseudo
     CDS             complement(34097..34279)
                     /locus_tag="ACL70N_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            34328..35092
                     /locus_tag="ACL70N_000902"
     CDS             34328..35092
                     /locus_tag="ACL70N_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGS0589723.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35705..37084
                     /locus_tag="ACL70N_000903"
     CDS             35705..37084
                     /locus_tag="ACL70N_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS0589724.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37098..37763
                     /locus_tag="ACL70N_000904"
     CDS             37098..37763
                     /locus_tag="ACL70N_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGS0589725.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37898..38056
                     /locus_tag="ACL70N_000905"
     CDS             37898..38056
                     /locus_tag="ACL70N_000905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589726.1"
                     /translation="MKIKDQTRKLAAGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            38118..38657
                     /locus_tag="ACL70N_000906"
     CDS             38118..38657
                     /locus_tag="ACL70N_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0589727.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            38724..39134
                     /locus_tag="ACL70N_000907"
     CDS             38724..39134
                     /locus_tag="ACL70N_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS0589728.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39250..>40376
                     /gene="pavB"
                     /locus_tag="ACL70N_000908"
     CDS             39250..>40376
                     /gene="pavB"
                     /locus_tag="ACL70N_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGS0589729.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETPGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLG"
BASE COUNT        11158 a         7833 c         9440 g        11945 t
ORIGIN      
        1 gtaaaaaagt gattagaaaa catctttttt aaaaatagag atgattttga aacaaaaaag
       61 ctaattcaag acgtttcgat gccaattcaa gatttggatg aaaaaaatta atagatactg
      121 ttatactaaa cttgtcaagt ttgtaacaag acaaatatta aaaataaaaa agaggtattc
      181 gttatgaata caaaaaagat gtcacaattt gaaattatgg atactgagat gcttgcttgc
      241 gttgaaggtg gcggatgcaa ttggggagat tttgccaaag caggtgttgg aggaggagca
      301 gcacgaggtc ttcagctagg aattaaaaca agaacatggc aaggtgcagc aactggtgct
      361 gcgggaggag ctatacttgg aggtgtggcc tatgcagcga catgttggtg gtaattatgg
      421 attttaaaag ttttattatt ggtttagtag ttggtatatt tggtccttat atggatgatt
      481 taattagaaa aaaattttta aagtcttcgg agaagaaaac agaaaaatct gttaaaaaat
      541 aatcaaaact ataaatgatg aatctgaatc aaaattattt tgcgcatgta aagaggagtc
      601 ttatagtaac gagtcaaaaa aggagtaact atgaatcgta atttagaacg gtgttatcta
      661 ttctgactag gaatagatca taccagaggt agcttagaaa tagcagagac attagaaatt
      721 gaagtaataa atgggatgtc gtaagtgtta ctatcaatga tttatttgtt tcaagcttgc
      781 ctagggtgac agtaaaaaat caatttcctt tcaatagcat atttttagtg ggcaggactc
      841 ttgttctgcc tattttttta tccaaaaagt gcagttggga gggagatagg ctcatttggg
      901 aaggaagtcc agtttttgtt tagtgattgg ggtaagatag ttgttatcag atgagtttat
      961 actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct tgccgtatat atgtgactga
     1021 cttcgtcagt cctatctaca acctcaaaac agtgttttga gcagcctgcg gctagtttcc
     1081 tagtttgctc tttgattttc attgagtatt agggaaaagg agatgaatat gaaatttggg
     1141 aaacgtcact atcgtccgca agtggatcag atggactgcg gtgtagcttc attagccatg
     1201 gtttttggct actatggtag ttattatttt ttggctcact tgcgagaatt ggctaagacg
     1261 accatggatg ggacgacggc tttgggcttg gtcaaggtgg cagaggagat tggttttgag
     1321 acgcgagcca ttaaggcgga tatgacgctt tttgacttgc cggatttgac ttttcctttt
     1381 gttgcccatg tgcttaagga agggaaattg ctccactact atgtggtgac tgggcaggat
     1441 aaggatagca ttcatattgc cgatccagat cccggggtga agttgactaa actgccacgt
     1501 gagcgttttg aggaagaatg gacaggagtg actcttttta tggcacctag tccagactat
     1561 aagccttata aggaacaaaa aaatggtctg ctctctttta tccctatatt agtgaagcag
     1621 cgtggcttga ttgccaatat cgttttggca acactcttgg taaccgtgat taacattgtg
     1681 ggttcttatt atctgcagtc tatcattgat acctatgtgc cagatcagat gcgttcgaca
     1741 ctagggatta tttctattgg gctagtcatc gtctacatcc tccagcaaat cttgtcttac
     1801 gctcaggagt atctcttgct tgttttgggg caacgcttgt cgattgacgt gattttgtcc
     1861 tatatcaagc atgtttttca cctccctatg tccttctttg cgacacgcag gacaggggag
     1921 atcgtgtctc gttttacaga tgctaacagt atcatcgatg cgctggcttc gaccatcctt
     1981 tcgattttcc tagatgtgtc aacggttgtc attatttccc ttgttctatt ttcacaaaat
     2041 accaatctct ttttcatgac tttattggcg cttcctatct acacagtgat tatctttgcc
     2101 tttatgaagc cgtttgaaaa gatgaatcgg gataccatgg aagccaatgc ggttctgttt
     2161 tcttctatca ttgaggacat caacggtatt gagactatca agtccttgac cagtgaaagt
     2221 cagcgttacc aaaaaattga caaggaattt gtggattatc tgaagaaatc ctttacctat
     2281 agtcgagcag agagtcagca aaaggctctg aaaaaggttg cccatctctt gcttaatgtc
     2341 ggcattctct ggatgggggc tgttctggtc atggatggca agatgagttt ggggcagttg
     2401 attacctata ataccttgct ggtttacttt accaattctt tggaaaatat catcaatctg
     2461 caaaccaagc ttcagacagc gcaggttgcc aataaccgtc taaatgaagt gtatctagta
     2521 gcttctgagt ttgaggagaa gaaaacagtt gaggatttga gcttgatgaa gggagatatg
     2581 accttcaagc aggttcatta caagtatggc tatggtcgag acgtcttgtc ggatatcaat
     2641 ttaaccgttc cccaagggtc taaggtggct tttgtgggga tttcagggtc aggtaagacg
     2701 actttggcca agatgatggt taatttttac gacccaagtc aaggggagat tagtctgggt
     2761 agtgtcaatc tcaatcagat tgataaaaaa gccctgcgcc agtacatcaa ctatctgcct
     2821 caacagccct atgtctttaa cggaacgatt ttggagaatc ttcttttggg agccaaggag
     2881 gggacgacac aggaagatat cttacgggcg gtcgaattgg cagagattcg agaggatatc
     2941 gagcgcatgc cactgaatta tcagacagaa ttgacttcgg atggggcagg gatttcaggt
     3001 ggtcaacgtc agagaatcgc tttggcgcgt gctctcttga cagatgcgcc ggtcttgatt
     3061 ttggatgagg cgactagcag tttggatatt ttgacagaga agcggattgt cgataatctc
     3121 atagctttgg acaagacctt gattttcatt gctcaccgct tgactattgc tgagcggaca
     3181 gagaaggtag ttgtcttgga tcagggcaag attgtcgaag aaggaaagca tgctgatttg
     3241 cttgcacagg gtggctttta cgcccatttg gtcaatagct agaaagagga gaggatgaaa
     3301 ccagaatttt tagaaagtgc ggagttttat aatcgtcgtt accataattt ttccagtagt
     3361 gtgattgtac ccatggccct tctgctcgtg tttttacttg gctttgcaac tgttgcagag
     3421 aaggagatga gtttgtccac tagagctact gtcgaaccca gtcgtatcct tgcaaatatc
     3481 cagtcaacta gcaacaatcg tattcttgtc aatcatttgg aagaaaataa gctggttaag
     3541 aagggggatc ttttggttca ataccaagaa ggggcagagg gtgtccaagc ggagtcctat
     3601 gccagtcagt tggacatgct aaaggatcaa aaaaagcaat tggagtatct gcaaaagagc
     3661 ctgcaagaag gggagaacca ctttccagag gaggataagt ttggctacca agccaccttt
     3721 cgcgactaca tcagtcaagc aggcagtctt agggctagta catcgcaaca aaatgagacc
     3781 atcgcgtccc agaatgcagc agctagccaa acccaatccg aaatcggcaa cctcatcagt
     3841 caaacagagg ctaaaattcg cgattaccag acagctaagt cagctattga aacaggtgct
     3901 tccttggccg gtcagaatct agcctactct ctttaccagt cctacaagtc tcagggcgag
     3961 gaaaatcccc aaactaaggt tcaggcagtt gcacaggttg aagcacagat ttctcagtta
     4021 gaatctagtc ttgctactta ccgtgtccag tatgcaggtt caggtaccca gcaagcctat
     4081 gcgtcagggt taagcagtca attggaatcc cttaaatccc aacacttggc aaaggttggt
     4141 caggaattga cccttctagc ccagaaaatc ttggaggcag agtcaggtaa gaaggtacag
     4201 ggaaatcttt tagacaaggg gaaaattacg gcgagtgagg atggggtgct tcatcttaat
     4261 cctgagacca gtgattctag catggttgca gaaggtgccc tactagccca actttatcca
     4321 tctttggaaa gagaagggaa agccaaactc acagcctatc taagttcaaa agatgtagca
     4381 agaatcaagg tcggtgattc tgttcgctat actacgactc atgatgccgg gaatcaattt
     4441 tttctagatt ctactattac aagtattgat gcgacagcta ctaagactga gaaagggaat
     4501 ttctttaaaa tcgaggcgga gactaatcta acttcggagc aggctgaaaa acttaggtac
     4561 ggggtggaag gccgtctaca gatgattacg ggcaagaaaa gttatctacg ttattatttg
     4621 gatcaatttt tgaacaaaga gtaatgttcg tgtttttaga gttaaataat ttttaaactg
     4681 tgagaaagat tcttcttgca gttttttctt tacaattttt gaaaaacata tgctatttat
     4741 tcggttaaat tcttgtgttt tttggttttt tgtggtaaaa tgtgctcaag taatacgaaa
     4801 ggcgaacttt aaaatgtcaa aacaattgat ctattcggga aaagctaaag atatctatac
     4861 aactgaggat gaaaatctta ttatttcaac ttacaaggac caggcgactg ctttcaacgg
     4921 tgtcaagaag gagcagattg taggtaaggg agtcttgaat aatcagatct catcttttat
     4981 ttttgagaaa ttaaatgcgg ctggtgtggc gactcacttt gtggagaaac tttcagacac
     5041 ggaacaactc aataaaaagg ttaagattat tcctttggaa gtcgtgctcc gcaactatac
     5101 tgctggttcc ttttcaaaac gttttggtgt ggatgaggga atcgccttgg agactccgat
     5161 tgtcgaattt tactacaaaa atgatgattt ggatgatcca tttatcaatg atgagcatgt
     5221 gaaattccta cagattgcgg gtgaccagca gattgcctac ttgaaggaag aaacgcgtcg
     5281 tatcaatgaa ctattgaaag tctggtttgc tgagattggg cttaaattga ttgactttaa
     5341 gctagagttc ggttttgaca aggatggcaa gattatcttg gcagacgaat tttcaccaga
     5401 taactgccgc ttgtgggacg ctgatggcaa ccacatggat aaggatgttt tccgtagagg
     5461 attgggagaa ctaaccgacg tttatgagat tgtttgggaa aagttgcagg aattgaaata
     5521 atctgtttgc aacggaaaac cttcgtctct caactaaaag gactcaggct gaaaaggtcc
     5581 cccagacctt ttcactctgt agagaactag gtgaactaac agatgtttac gaaattgtct
     5641 gggaaaagtt gcagggttta aaataacaac ctcaaggctg tttgggaata ttgcaagagc
     5701 tgaaataaag gaataagaat tgatggataa acgtattttt gttgaaaaaa aggctgattt
     5761 tcaggtcaag tcagagagtt tggttagaga gctccagcac aacttgggac tgtcaagctt
     5821 gaaaagtatt cgtattgtgc aagtatatga tgtatttgac ttggctgagg acttgtttgc
     5881 acctgcagag aagcacattt tctctgagca gggaaccgac catgttttag atgaagtatc
     5941 tgtgcaggcg gatcttgcta actatgcttt ctttgccatt gaaagtctgc cagggcagtt
     6001 tgaccagcgt gcagcttcgt cacaggaagc cttgcttttg ttgggaagtt cgagtgacgt
     6061 gacagtcaac acagcccaac tttacttggt gaataaagat attgatgcga ctgagttgga
     6121 agctgtcaaa aactacctgc tcaatccagt tgattctcgt ttcaaggata tcacgacagg
     6181 gattgccaag caggagtttt cagagtcaga caagaccatt ccaaaattga ctttctttga
     6241 aagctataca gcagaagact ttgctcgcta caaggccgag caagggatgg ccatggaagt
     6301 ggatgatttg ctctttatcc aagactactt taagtcaatc gggcgcgtgc caactgagac
     6361 tgaactcaag gttttggaca cttactggtc tgaccactgc cgtcatacga cttttgagac
     6421 agagttgaaa cacatcgact tttcagcttc taaatttcaa aagcaattgc agtcaaccta
     6481 tgacaagtat attgccatgc gcgaggagtt aggtcggtct gaaaaaccac aaaccttgat
     6541 ggatatggcg actattttcg gtcgttatga gcgtgctaat ggacgattgg atgatatgga
     6601 agtctctgac gaaatcaatg cctgctcagt tgaaattgaa gtggatgttg atggtgtcaa
     6661 ggaaccttgg ctcctcatgt ttaaaaatga aacccacaac catccaacag aaattgagcc
     6721 atttggtgga gcggctacct gtatcggtgg agctattcgt gatccgttgt caggccgttc
     6781 ctatgtttac caagccatgc gtatttcagg tgctggtgat attacagcac cgatttcgga
     6841 aactcgtgct gggaaattgc cacaacaagt catttctaaa acagcagctc atggttattc
     6901 ttcatatggt aaccagattg ggcttgccac aacctacgtt cgtgaatact tccacccagg
     6961 ctttgtagct aaacgtatgg aacttggtgc cgttgttggt gcggctccca agggcaatgt
     7021 tgtccgtgaa aaacctgaag caggtgatgt gatcatcctt ctcggaggca aaacaggtcg
     7081 tgatggtgtc ggtggtgcga cgggctcttc taaggttcaa acagttgagt ctgtagagac
     7141 tgctggtgct gaggttcaaa aaggaaatgc catcgaagaa cgcaagattc agcgcctctt
     7201 ccgtaatggc aatgtcactc gtctgatcaa gaagtccaat gactttgggg caggcggcgt
     7261 ctgtgtggct atcggtgaat tggcagacgg tcttgaaatc gacctcaaca aggtgcctct
     7321 taaataccag ggcttgaatg gtacagaaat tgccatctct gaatcacaag aacggatggc
     7381 ggtcgtggtt cgtcctgaag atgtggatac cttcgttgcc gaatgtaaca aagaaaatat
     7441 tgatgctgtt gtggtggcga cagtaactga aaaaccaaat cttgtcatgc actggaatgg
     7501 tgagacaatc gttgacttgg agcgtcgttt ccttgacacc aatggtgtgc gcgtggttgt
     7561 cgatgccaaa gttgtggaca aggatgtcaa actcccagaa gagcgtcaaa catctgctga
     7621 aacactggaa tcagataccc ttacggttct atctgacctc aaccatgcaa gtcaaaaagg
     7681 attacagact atctttgact gctctgttgg acgctcaacg gttaatcacc cacttggtgg
     7741 tcgttaccaa ctcacaccaa ctgaggcatc tgtgcagaaa ttgccagttc aacacggtgt
     7801 gactcatact gcgtcggtca ttgctcaagg tttcaaccca tatgtagctg aatggtctcc
     7861 ataccacggt gctgcttatg cggttatcga agcaactgct cgtttggtgg ctgctggtgc
     7921 caactggtcc aaggctcgtt tctcttacca agagtatttc gagcgtatgg ataaacaagc
     7981 agagcgtttc ggtcagccag tagctgctct tctaggttct attgaagcac aaattcagct
     8041 tggcttgcca tctatcggtg gtaaggactc catgtctggt acctttgaag aattgaccgt
     8101 tccgccaacc ttggttgcct ttggggtgac gacggcagat agccgtaagg tgctctctcc
     8161 agaatttaaa gctgttgggg aaaatatcta ctacatccca ggtcaagccc tctctgcaga
     8221 gattgatttt gacttgatta agaaaaattt tactcagttt gaagccatcc aagctgacca
     8281 taaagtgaca tctgcatcag ctgtcaaata cggtggtgta gttgaaagtt tggctcttgc
     8341 tacctttgga aactatattg gtgcagaggt gaccttgcct gaacttaaaa cagctttgac
     8401 agctcaatta ggcggctttg tcttcacatc tcctgaagaa attgctggag tagagaaggt
     8461 tggacaaacg aaagcagact ttacactgac tgtcaacggt gtgaagctag atggacacaa
     8521 gcttgacagt gcatttcaag ggacattgga agaagtttac ccaacagaat ttacccaagc
     8581 gaaagaacta gaagaagtac cagctgtggc atcagatgtt gtgattaaag ccaaagaaaa
     8641 ggttgaaaaa cctgtggttt acatcccagt ctttccagga accaactcag aatatgattc
     8701 agctaaggcc ttcgaaaaag aaggtgcaga ggtcaatttg gtgccattcg tgaccttgaa
     8761 tgaagaagct attgtcaagt cagttgaaac tatggttgac aatatcgaca agactaatat
     8821 tctcttcttt gctggtggat tctcggctgc ggatgaacca gatggttcag ctaagtttat
     8881 cgtcaatatc ctgcttaatg aaaaagtgtg tgtggctatt gatagcttta tcgcccgtgg
     8941 tggtttgatt atcggtattt gtaatggatt ccaagcctta gtcaaatcgg gtctcctacc
     9001 ctacggaaac tttgaagctg ctaacagtac tagcccaacc ctcttctaca atgatgccaa
     9061 ccaacacgtg gccaagatgg tggaaactcg cattgccaat accaactcac catggttggc
     9121 tggtgtgcaa gtgggcgata tccacgctat tcctgtttcg cacggtgaag ggaagtttgt
     9181 cgtgacggct gaggaatttg cagagctccg tgacaatgga caaattttca gccaatacgt
     9241 tgactttaac ggtaaaccaa gtatggattc taagtacaat ccgaatggtt ctgtccatgc
     9301 catcgaagga attaccagca agaatggtca aatcatcggt aagatgggcc actcagaacg
     9361 ttatgaggat ggtcttttcc aaaatatccc aggcaataaa gaccaacacc tgttcgcatc
     9421 agcggttaaa catttcactg gaaaataaga cttacagatt ttctaataga tagtatcagt
     9481 aatgtaaaag tcatgtaaat ctagctcttg atgattacaa atgaaaatta ggtataaaaa
     9541 atgacatacg aagtaaaatc tcttaatgaa gaatgtggtg ttttcggtat ttggggacat
     9601 ccagatgctg ctaagttgac ctattttgga ctccacagtc ttcaacaccg tggtcaggag
     9661 ggggcaggaa tcctctccaa tgatcaagga caactgaagc gccatcgtga catggggctt
     9721 ttatcagaag ttttcagaaa tccagccaat ttggataaat tgacaggagc tggtgcgatt
     9781 gggcatgtgc gttatgcgac tgctggcgaa gcttctgttg ataacatcca acccttcctc
     9841 ttccgttttc acgatatgca gtttggtttg gctcataatg gaaatctgac caatgcagcc
     9901 tctctcaaga aagaactgga acaaagagga gcaattttca gcgcgacttc ggactctgaa
     9961 atcttggctc acctcattcg tcgcagtcat aatcctagcc tgatgggcaa aatcaaggaa
    10021 gcgctcagcc ttgtcaaagg tggttttgcc tatatcttgc tgtttgagga caagttgatt
    10081 gcggctcttg accctaatgg ctttcgtccg ctttctatcg ggaaaatggc caacggagcg
    10141 gtggttgttt cctctgaaac ctgtgctttt gaggtcattg gtgccgagtg gattcgtgat
    10201 ttgaagccag gtgagattgt gatcattgat gacgagggca ttcagtatga cagctataca
    10261 gatgataccc agttggcgat ttgttctatg gagtatatct actttgcccg ccctgattct
    10321 aatatccacg gtgtcaatgt ccatacggca cgtaagagaa tgggagcgca attggcgcga
    10381 gaatttaagc atgaggcaga tattgtagtt ggtgtgccca attcttccct aagcgcggct
    10441 atgggatttg cggaagaatc aggcttacca aatgaaatgg gtctgatcaa aaaccaatac
    10501 acccagcgaa cttttatcca accgactcaa gaattgcggg agcaaggagt gcggatgaaa
    10561 ctgtctgctg tttcgggtgt tgtcaaaggc aaacgtgtgg ttatggtgga tgattccatt
    10621 gtacgtggaa caacctctcg tcgtatcgtt cagctcttga aagaagcggg tgcgactgag
    10681 gttcacgttg ccattggaag tcctgcacta gcgtatccat gtttctacgg gattgatatc
    10741 cagacccgtc aggagctgat tgcagccaat catacggtcg aagaaactcg ccaaatcatt
    10801 ggtgcggaca gtctgactta tctttcaatt gatagcttga ttgagtcgat tggtatcgaa
    10861 acagatgcgc cgaacggtgg tctctgtgtc gcttactttg acggtgacta cccaacgcct
    10921 ctctatgact acgaagaaga ctatcgtaga agtttggaag aaaagaccag tttttacaag
    10981 taggcgacag attctccatt aaagaaaagg aaaaaacaaa tgacaaataa aaatgcatat
    11041 gcccagtcgg gtgtggatgt tgaagcgggt tatgaagttg ttgaacggat taaaaagcac
    11101 gtggcccgta cggagcgtgc aggtgtcatg ggagctcttg gtggctttgg tggtatgttt
    11161 gacctttcca agactggggt taaagaaccc gtcttgattt cagggactga cggtgtcgga
    11221 accaagctca tgttggctat caagtacgac aagcacgata ccatcgggca ggactgtgtg
    11281 gccatgtgtg tcaacgacat cattgctgca ggtgcggaac ccctctattt tctcgactac
    11341 gtagcgacag ggaagaatga accagctaag ctagaacaag tggttgctgg tgtggcagaa
    11401 ggttgtgtgc aggctggtgc tgccctcatc ggtggggaaa cggctgaaat gccgggcatg
    11461 tacggcgaag acgactatga cttggctggt tttgcggtcg gtgtggctga aaaatctcaa
    11521 atcattgacg gttcaaaggt ggtagaggga gatgttcttc tcggacttgc ttcaagtggg
    11581 attcactcaa atggttactc tttggttcgt cgtgtctttg cggattacac aggtgaggaa
    11641 gtcctaccag aattggaagg caagaaactt aaggaagttc tacttgagcc gactcgtatc
    11701 tatgtcaagg ctgtcttgcc gctcatcaaa gaagagttgg tcaacggcat tgcccacatc
    11761 acaggtggtg gctttatcga aaatgtccct cgtatgtttg cagatgacct agctgctgaa
    11821 attgatgaaa gcaaagttcc agtgcttcca attttcaaag cccttgaaaa atatggtcag
    11881 attaaacacg aagaaatgtt tgaaatcttc aatatgggtg tgggacttat gttggcggtc
    11941 agccctgaaa atgtagagcg tgtaaaagaa ttgttggatg aagcagtcta tgaaattggt
    12001 cgcatcgtca agaaagaaaa cgaaagtgtc attatcaaat gaaaaaaata gcggtttttg
    12061 cctctggtaa tggctcaaat tttcaggtga ttgccgaaga atttccagtg gagtttgtct
    12121 tttcagacca tcgtgatgcc tatgtgcttg agcgtgcaaa gcagctcggc gttctgtcct
    12181 atgcttttga actcaaggag tttgagagca aggcagacta cgaagcagcc cttgtcgaac
    12241 tcttggaaga acaccagatt gacttggttt gcctagcagg ctacatgaaa atcgttggac
    12301 caaccttatt gtcggcttat gaaggtcgga ttgtcaacat tcatccagcc tacttgccag
    12361 aatttccagg agctcatggg attgaggatg cttggaatgc tggcgtgggt cagtctggtg
    12421 tgaccattca ctgggtggat tcgggtgtgg atacaggcca ggtcatcaaa caggttcgtg
    12481 tgccacgact agctgatgat accattgaca gatttgaagc tcgcatccat gaagcagagt
    12541 acaggctgta tccggaagta gtgaaggctc tatttacaga ttgacttttt gatgattcat
    12601 atgatatctt tgattttaaa ttggagtcag tgtttgttga agacggcttc aaacggaggt
    12661 atttgtaata ttagaatcta aaaaaacaac tcgatatgta ttttatgtct atctgatgtt
    12721 attaacttgg ggaatcttat ttaagtttga aacaaatcct gaatttatag catttttctt
    12781 agctccaagg tatatcaatt ggattccatt ttcagaacca ctaatagtcg atggaaaaat
    12841 tgtttttgct gaaatgttat ttaatctgat ttcctttatt ccattaggtg tttgtttccc
    12901 tttgataaaa actaatttat ctagtttaag aatagtcggg acaggtttct tgattagttt
    12961 attgtttgag tgcttacagt atattttagc aataggtata acagatataa cggatttgac
    13021 tttaaatacg ctaggtgtct gtgtaggctt actgatttat caaattttta taagagtgtt
    13081 caaatcacag actagaaaat ggatcaatat cttaggtatg cttagccttg gttttgctta
    13141 tcttgtttta ctgttactgc atttaattgg tgtttaacta atgattaaaa aggagaatat
    13201 aatgactaaa cgcgtcttaa tcagcgtctc agacaaagcg ggcattgttg aatttgccca
    13261 agaactcaaa aaacttggtt gggagattat ctcgacaggt ggaactaagg ttgcccttga
    13321 taatgctggg gtggatacca ttgctatcga tgatgtgact ggtttcccag aaatgatgga
    13381 cggtcgtgtg aagaccctcc acccaaatat ccacgggggg cttctcgctc gtcgtgactt
    13441 ggatagccac ttggaagcgg ctaaggacaa caagattgag ctcattgacc ttgtggtggt
    13501 caacctttac ccatttaagg aaactatcct taaaccagat gcgacttatg ctgatgcagt
    13561 tgaaaatatc gatattggtg ggccatctat gcttcgttca gcagcgaaaa atcatgccag
    13621 tgttacagtt gtggtagatc ctgctgacta cgctgtggtt ttggacgaat tggcagcaaa
    13681 cggcgaaacc tcttatgaaa ctcgccaacg tttagcagcc aaagtatttc gtcacacagc
    13741 ggcttatgac gccttgattg cagaatactt cacagctcaa gtgggtgaaa gcaagcctga
    13801 aaaactcact ttgacttatg acctcaagca accaatgcgt tacggtgaga atcctcaaca
    13861 agacgcggac ttttaccaga aagctttgcc tacagactac tccattgctt cagccaaaca
    13921 gctcaacggg aaagaattgt catttaataa tatccgtgat gcagatgctg ctatccgtat
    13981 catccgtgac ttcaaagata gtccaaccgt tgtggctctc aaacacatga atccatgtgg
    14041 aattggtcaa gctgatgaca tcgagactgc ttgggactac gcttatgagt ctgacccagt
    14101 gtctatcttt ggtgggattg tcgtcctcaa ccgtgaggtg gatgctgcga cagctgagaa
    14161 gatgcacggc gttttcctcg aaatcatcat tgcaccaagc tatacggatg aagcgctagc
    14221 cattttgatc aataaaaaga aaaacttgcg tatccttgcc ttgccattta atgctcaaga
    14281 ggctagcgaa gtggaagcag aatacacagg tgtagtcggt ggacttctcg tgcaaaatca
    14341 agacgtggtc aaggaaagcc cagctgactg gcaagtggtg accaaacgtc agccaaccga
    14401 gacagaagcg actgctcttg agttcgcttg gaaggctatc aagtacgtca aatcaaatgg
    14461 tattatcgtg accaacgacc acatgacact tggtgttggt ccaggtcaaa ccaaccgtgt
    14521 ggcttctgtt cgccttgcca ttgaccaagc caaagatcgt ctggacgggg cggtccttgc
    14581 ttcagatgcc ttcttcccat ttgcggataa cgtggaagaa atcgctaaag caggaattaa
    14641 ggccatcatc cagcccggtg gctctgtccg tgaccaagaa tccatcgaag cagcggataa
    14701 atacggcttg actatggtct ttacaggtgt gagacatttt agacattaag aagataaaag
    14761 ggaagaaaac agtttctttc cttttttggc ttaaaatgct aactgaaaca agattaaaac
    14821 gaactttttt gatataatat tggtaaataa ttcgcaaaag aggttgagga atgaaactgc
    14881 ttgttgtcgg ttcgggtggt cgtgagcatg cgattgctaa aaagttactt gaatcaaaag
    14941 atgtggaaaa agtctttgta gctcctggga atgatgggat gactctggat ggtttggaat
    15001 tggtaaatat ctctatttcc gaacattcta aattgattga cttcgcaaag accaatgatg
    15061 ttgcttggac ctttatcggt ccagatgatg cccttgctgc tggtatcgtg gatgatttta
    15121 accaagctgg gcttaagacc tttggtccga ctagggctgc agcggagctg gagtggtcca
    15181 aggattttgc caaggaaatc atggtcaaat atggtgtttc gacagcagcc tatggcacat
    15241 tttcagattt cgaggaagca aaggcttata tcgaaaagca tggtgcgcct atcgtagtca
    15301 aggcggatgg cttggcgctt gggaagggtg tcgtcgttgc tgagacggtt gagcaagcgg
    15361 tcgaagccgc tcatgagatg cttttggaca ataaatttgg tgactcaggt gcgcgcgtgg
    15421 ttattgagga attccttgaa ggagaggaat tttcactctt tgcctttgtc aatggtgata
    15481 agttctacat catgccaacg gctcaggacc acaaacgtgc ctacgatggc gacaaagggc
    15541 ctaacacggg tggtatgggt gcctatgcgc cagttccaca cttaccacag agtgtagttg
    15601 atacagcggt tgacaccatt gtcaagccag ttctagaagg gatgattaaa gaaggtcgcc
    15661 cttatctggg agttctttac gcagggctta tcctgacagc tgatggaccg aaagtcatcg
    15721 agttcaacgc tcggttcgga gatccagaaa ctcagattat cttgcctcgc ttaacctctg
    15781 actttgctca aaatatcaca gatatcctgg atagcaagga gccaaatatc atgtggacgg
    15841 acaagggtgt gactctgggt gtggttgtcg catccaaggg ctacccgcta gactatgaaa
    15901 ggggcgttga gttgccagcc aagacagaag gcgatgtcat cacctactat gcaggggcta
    15961 agtttgcgga aaatagcaga gcactgctct caaacggcgg acgagtttat atgctcgtta
    16021 ccacagcaga taccgtcaaa gaagcccaag ccagcatcta ccaagaacta tcccaacaaa
    16081 aaatagaagg actcttctac cgaacagata tcggaagcaa ggcaattaag taaagatata
    16141 agaataacgc gccgtagtcg ccaaacacga taatggtcgt cgtggtgaaa agaccagaac
    16201 agtgaatgtt ctggtcaggg ggaaatttgg agaccgtagg ctcaaagttt aggaatgaaa
    16261 ccgaaggttt gcttccgcct ccatcaccta agatcattat taaaaaagaa gaaaaggaaa
    16321 attatgacca aaccaattat ttccatcatc atgggctcaa aatccgattg ggcaaccatg
    16381 caaaaaacag cagaagtctt agaccgcttc ggtgtagcct acgaaaagaa agttgtttct
    16441 gcccaccgta cacctgatct catgttcaaa catgcagaag aagcatatag ccgtggtatt
    16501 aaggtcatca tcgcaggtgc tggaggcgca gcccacttgc caggaatggt agctgccaaa
    16561 acaacccttc ctgtcatagg ggtacctgtc aagtctcgtg ctcttagtgg agtggattca
    16621 ctctattcta tcgttcagat gccgggtggg gtgcctgttg cgaccatggc tatcggtgaa
    16681 gctggagcga ctaacgcagc tctctttgcc ctccgtctcc tctctgtaga agataagtcc
    16741 attgcggatg cacttgccaa ctttgctgaa gaacaaggaa aaatcgcaga ggagtcgtca
    16801 aatgagctca tctaaaacaa tcggaattat cggtggcggt caactgggtc agatgatggc
    16861 catttctgct atctacatgg gccacaaggt tatcgcgctg gatcctgcgg cggattgccc
    16921 ggtctctcgt gtggcggaaa tcattgtggc accttataac gatgtagacg ccctccgtca
    16981 gttggcagac cgttgcgatg tcctcactta cgagtttgaa aatgtcgacg ctgacggttt
    17041 ggatgccgtt atcaaggatg gacaactccc tcaagggaca gacctgctcc gcatttcgca
    17101 aaatcgtatt tttgaaaagg actttttgtc aaacaaggct caagtcactg tggcacccta
    17161 caaggtcgtg acttctagcc tagacttggc agatatcgac ttgtcgaaaa actatgtcct
    17221 caagactgcg actggtggct acgatggtca tggacaaaag gttattcgtt cagaagtaga
    17281 cttggaagca gcctatgcgc tagcagaatc agcagactgc gtcttggaag aatttgtcaa
    17341 ctttgccctt gagatttctg tcatcgtgtc aggaaatggc aaggaggtga cgtttttccc
    17401 agttcaggaa aatatccacc gcaacaatat cctgtctaag accatcgtac cagcccgcat
    17461 ttctgaaagt ctagtagaca aggctaaagc tatggcagtg cgaatcgcag aacaactcaa
    17521 cttgtctgga actctctgtg tggaaatgtt tgcgactgat gatgacgtta ttgtcaatga
    17581 aatcgcccca cgaccacata actctgggca ctattctatt gaagcctgtg atttctctca
    17641 gtttgacacc catattctcg gtgttctcgg agcaccatta ccagtcatca aactccatgc
    17701 gccagccgtt atgctcaatg tcctaggtca acacgtcgag gctgctgaaa agtatgtcgc
    17761 agaaaatcca agcgcccacc tccacatgta tggtaaaata gaagcaaagc ataatcgtaa
    17821 gatgggacat gtgaccttgt ttagtgatgt accggatagt gtggatgagc ttggggaagg
    17881 gattgatttt taggacaagt ctatgataca aattatcgtt aatacattta ttgaaaagga
    17941 taagactgga gcagttgttg aagtgttgta tgccagtgct gaccaagata aggtacaagc
    18001 taaatatgaa gaactagctg cacaataccc cgaaaattat ttagctatct atgatgtacc
    18061 gctggatacg gatttgaata cactagatca ttacccgtct gtgtttattg gaaaagagga
    18121 gtttgagtag aaatcttggt ttacctagat agcttattcc caacagctta agaagaaagg
    18181 aaaaattaac acatgatcaa ccgttactct cgccctgaga tggcgaatat ttggagtgaa
    18241 gaaaataaat accgtgcttg gcttgaggtg gaaatcctct ctgacgaggc atgggctgag
    18301 ttgggggaaa tccctaagga agatgtggct ttgattcgca agaaggcgga ctttgacatc
    18361 gaccgtattt tggaaattga gcaggagacg cgccacgatg tggtggcttt cacgcgtgcg
    18421 gtttctgaga ctcttggtga agagcgcaag tgggttcact atgggttaac ttctaccgac
    18481 gtggtggata ctgcttatgg ttacctctac aagcaggcca acgacatcat ccgtcgtgac
    18541 cttgaaaact tcactaatat catcgctgac aaggccaagg agcacaagtt caccatcatg
    18601 atggggcgta ctcatggtgt gcacgctgag ccgacaacct ttggtcttaa attggcaact
    18661 tggtacagcg aaatgaaacg caatatcgag cgcttcgagc atgcggctgc tggtgtagaa
    18721 gctggtaaga tttctggtgc ggttgggaac tttgccaata tcccaccatt tgtagaggag
    18781 tatgtctgcg ataaacttgg catccgtgcc caagaaatct ctacacaagt ccttcctcgt
    18841 gaccttcacg ctgagtactt tgcggttctt gccagcattg cgacttcaat cgaacgtatg
    18901 gcgactgaga ttcgtggtct acaaaaatct gagcaacgcg aagtagaaga gttctttgct
    18961 aaagggcaaa aagggtcttc agcaatgcct cacaaacgca acccaatcgg ttctgaaaat
    19021 atgactggtc tggcgcgtgt cattcgtggt cacatgatta cggcttatga aaacgtcgct
    19081 ctctggcacg aacgcgatat ttctcactca tcagctgagc gtatcatcac accagatacg
    19141 accattttga ttgactacat gctcaaccgt tttggaaata tcgtcaagaa cttgacagtc
    19201 ttcccagaaa atatgatccg aaacatgaac tcgacttttg gtcttatctt tagccaacgg
    19261 gctatgttga cattgattga aaaaggcatg acccgtgagc aagcctatga cttggtgcaa
    19321 ccaaaaacag cctactcttg ggacaaccaa gtagacttta aaccacttct tgaggcagat
    19381 tcagaagtaa catcacgtct cacacaagaa gaaatcgatg aaatcttcaa cccagtttat
    19441 tacaccaaac gagtggatga tatctttgaa cgtcttggac taggtgatta attaaaaaat
    19501 aaacagcgag cttcaatctc gctgtttatt ttttatcgaa aagacttagt cttcttttct
    19561 tttagtgagt ccataggctg ctagtgtgga catgagtcct gcgactacta gtcctgcaga
    19621 atcgtgagtt cctgtttcag gaagtttttt ctctgttacc acaggagctg gatcttgagg
    19681 aagaactttg ctttcctcag caggagcagt tgatggagct ggttggcttg ggatttctag
    19741 ttttggtttt tcttcagcaa tagcggcttg tccgttttca tcgcctacat gtgttaccat
    19801 agttccgact tcgactattt gagtaacggc ttcctgtgct acgacactat ttacaagtgt
    19861 tttcacttcc ttaccatcgg cagaagtgct cacagagtag aagttgctac gatgtccatt
    19921 gacgccctta gtaatgactt gtgtttttcc tttgagtaag agtggatttt cacgagtcac
    19981 tgtggtaaat ggaatgtctt cttcttggat atccagtcta ggttttacct cagtagttgg
    20041 tgcaagacca ctttcatcac ccttgtgagt tacaggagcg ccaacttcaa ccacttggtt
    20101 tataacttct ttggttacct ggctatcaag gactgtttct gttgtttttc cattttcagt
    20161 gagtacagag atgtaatgag ttcgttcacc tttgactcct gctgtgataa tattttcctg
    20221 accggctggg aggttaggat tttctttctt gataacttca aatggaattt cttcagttct
    20281 tgtgatgagt tctggtctgg tttcaacatt ggcagccact tcattttcat ctaggcttcc
    20341 tgaatgagtt acagctggtt tgaggccttg aagagcggct tttaggttgg ctacaagtgt
    20401 gtcaagctca gcttgtttat tacggttgag gttgtaattt agagctgttt tagctgcgtc
    20461 aagggcctca agactttctt tactatatcc ttctaagttt gtaggaattt tagctaattc
    20521 ttcgcggaga gcattataat tagcacggaa gtagtctttg ttgtggtctg caaaggcagt
    20581 catgagttca aagatttcct cttccttgta ttcagcgctt ggtctatctg cccagattga
    20641 aagcatactt ccgactgttg gaagatctac ttcaggatat ttggtagaag ctagttgatt
    20701 gaatggtgtt tttccagtat tctcaatagc tttcttgagg aaaccaccac catcttctgg
    20761 tttttgacca agaatgtagt accagtcacc gttggtattc aagaatttat agcctttgct
    20821 tgctaggtat tgaggtgatg cgaggttata tccccaccag cctttagacc agtaagaaat
    20881 caagacatct ttgtcaaact gaacatcgtc cttgtcttca tagtagaagc catcgttgaa
    20941 ggccattggt tgaagccctc tttctttggc catagctgcg agggtgttgg catattcggc
    21001 aaatttgcca tagagttgat accacttgag gtagtaccag ccttgggcac tagtcgcatc
    21061 gttggcgtat tcgtcagtac caaagttgaa aatctttgtt ttacctgcaa agaagtccat
    21121 gtatttaccg atgagggctt ttacaaagtt catcgcttct tcgtttttca agtccatagt
    21181 tgtttttgaa actttatcaa agtgggcttg aggattttta atacctaatt tttccatggc
    21241 aaccagcata gcatccatgt gacctggact gttaatagct gggatgagac cgatgtcctt
    21301 agatttagcg tattcaatta gctctgtcac ttctgcctgt gttagtgcag taccgtttgg
    21361 atcgtcgtag taagctttag ttccttcgat aatagctttt ttaacgtcat cactagcata
    21421 ggtttttccg ttggcagtaa tggtcatatc atcgagtaga aagcgaagtc cgtcatttcc
    21481 tagaaggaga tggacatcag aatatccgag ctcactggcc ttgtctacga tgcgtttgag
    21541 ctggttcaga gtaaagtatt tgcgtccagc atcgattgag attatcttgt ttttggcaag
    21601 tttttcaacc tcacgtttag cttcttcttc tttttgagct tcaggcgtga gggtcaagtt
    21661 gttgacagtt tcttgaagtt tagcaatggc ttgatcaatc gtatcttgtt gggcacggct
    21721 aaggttgcta tcgagagagc gaatagcttt ttcagcttct tttacggccg tgacgctttc
    21781 tgcagtataa cggttcaggt cttttggtac ctcgttaagt gcttgctctg cagattcata
    21841 atcagctgcg aagtattcag cgttggcatt tgcaaaatga cgcatgagtt tgaagaggcg
    21901 tgatggtgaa taacgtgcag atggagtgtc agcccaagca gctaccatac caccgatgat
    21961 tgggatatca gctccttctg tttttggtac agaagtgatt ggtgtgtttt taataccatt
    22021 gagcccctga tcgagattgt accagccttg gccatcagcg tttcgtccaa gaacgtagta
    22081 ccaagcatca ttggtattaa ggatttggtg acctttttca gctagtagtt tagaagaagc
    22141 gacatcgtag cctccccaac caccagtcca catagaaacg atgatgtctt tgtcaaaact
    22201 accaaagctt gtgtcgctat tgtagtagat accgtcgtta aaggccattg gtttgagacc
    22261 gtgcgatttt acaatacgag cgaggtcatt ggcgtaggca ataaattttt catagccttt
    22321 tacagggtag ccttcgtttg gatagtattt atcagcttga agcacactcc aacctttagc
    22381 atctgtcgca tcattggcat attcatcaag tccgatgttg aagatttcag tctttttcgc
    22441 gaaataagca gcatacttgt cgataagggc ttttgtaaaa gcgacagctt gttcgttgtc
    22501 aagatcgaca gtacgggctg attccttccc aaaatagcta aagttagggt tttggattcc
    22561 caattctttc atggcattga gaatcgcatc catgtgccca ggactattta ctgtcggaat
    22621 gagaccgata cctttatctt tggcatagtt aatcagatct gtcatttgac tttctgttaa
    22681 gtgattgccg tttggatcgt cgtaataatc atttgtacct ttttcaatgg cgcgtttgac
    22741 atcgtcactg gcataggtct tgccgttagc tgtgatgctc atatcgtcca acatgaaacg
    22801 gagtccatca tttccgacta ataggtgtaa atcagtgtag ccataatgtt tcgctttatc
    22861 gatgatttcc ttgagctgtt ctggtgagaa atatttacgt ccagcatcaa tagaaacaat
    22921 tttctttttc gctagttttt catttacagt tgcagcacgt tcctttcctg cctctgtttc
    22981 cggtttgtca gcctctgctt tcgcttcatc ttttttagct ggtttatcct tgtcagtctt
    23041 gtctgtattt gactctttag aatcaacctc tttcgcttct tcctttttag ggctagcttc
    23101 ttctgccttt ttattagcag tttctttttc agcagaagtt ggagttacca cgtctgcttt
    23161 atcactagga gttgaactaa cttcctcttg tggtttttct tctgtttttg gaagactagc
    23221 taccttatca gtagctggag tttctgtttc tacagttttt ggagcttctg gttgaagctc
    23281 tgctttaggt gtttcctcag tccgattttc ggatgattga ggggaatcag aaaccgtatg
    23341 gatggtcggt tggttttctg tagtagtagg agtaactcca tcggctgcaa cagtctgtgc
    23401 ttggaaggca aatccaatta gaacagaagc tgctcctaca gcgtatttac gaatagaaaa
    23461 acgctgttgt ttttcatgtt tcattgcaaa acctcctgat tgcattgtta tattgatagc
    23521 gattatataa atcaacgcct ttattttatt tcttatatta acgagagtca agaggagatg
    23581 acaaaaaact ataataagta taaaaaaata taaaatttaa acttaagatt tcagattggt
    23641 cgaaaataca tatatatatc tagtataatt tttggttcta tttctataaa atattccaca
    23701 aattatagaa tcttccaaaa ataggtaagc gctacctttt tggtgtggta taataagcat
    23761 agaaaaagcc cgagcgatta ggctcaggct ttcttcttag tgatcacggt cacatgagat
    23821 gaattcaatc ttgtagtaat cagatcgttt gtaagtttca ctgtattcta aaacttggcc
    23881 agttgattcg agtttggtga ttttagtttg taggacagta gggaattgtt catcgactcc
    23941 gaggactgaa gccgcatgtt ctggagttgg aaagactatt tcgttgattt cttcaaagtg
    24001 ttcatcattc atgtgaatgt ggtagtctaa cttgaaacga ttatagatag aactatagta
    24061 ttcaaggttt ggataatttg cgttgatata ttgttctggg atgtaggatg tatggtagat
    24121 ataaacgaca ccgtttgatt cgcggatacg ttcaatcttg tagtagaatt gatcgccgcg
    24181 tagacccaat ttttccaagt aaacaagctt gtttccgcgt tcaattgaaa gaacagttac
    24241 cttatcatct ttagcattga agagttcaat atctgaaaac tctacaagct tgtgtttgcg
    24301 tgcacgtgaa acgaaggttc cttttccttg ttggcggaca atatagccat ctttggcaag
    24361 gtcgtttaag gcgcgaacaa ctgtgataga gctgacatcg tacattgaaa tgagttctgc
    24421 ttcagtgtaa aatttatctc cactgctaaa ctgcccagag atgattttat tttttaattc
    24481 gtcttttatg tattgatatt tgggaattgc catattttta cctctatttt ccttctccat
    24541 agaaaatttt accataaaag cgaaaaaaat agtagtcttt tgaataaaaa attagaataa
    24601 tagtttgaaa aattaagcga tatagggatt gctcatattt tatcaatgta ttctatacaa
    24661 aattatttta ggtcctatat tccgaattta aagagcgttt gaaatgggtc taaaaatgtt
    24721 tgaaactaat tgaatgtgtg tataatagta aaaatgcagt aaatatcccg acaatttcta
    24781 ttgacaattc aaacagattg gtttataatt aatataacaa caaatgaaag cgcaaacttt
    24841 cgcggtcgga aggtagtttt atgacacgat ttgagatacg agatgatttc tatctcgatg
    24901 gaaaatcatt taagatttta tctggtgcca ttcattattt tagggttcct ccagaggatt
    24961 ggtatcattc gctctataac ttgaaggctc ttggttttaa tacggtagag acttatattg
    25021 cttggaattt acacgagcct cgtgaaggtg agtttcattt tgacggtgat ctggatttag
    25081 agaaatttct ccaaatagcg caggatttgg gtctctacgc aattgtgcgt ccgtctccat
    25141 ttatctgtgc ggaatgggaa ttcggtggct taccagcttg gctcttgacc aagaacatgc
    25201 gaattcgctc atccgaccca gcatatatcg aggcagttgg tcgctactat gatcagttat
    25261 tgccaagact ggtgcctcgt ttgttggaca atggtggcaa tattctcatg atgcaggttg
    25321 aaaatgagta tggttcttac ggagaagata aggcttacct gagagcgatt cgacagctaa
    25381 tggaagagcg tggcgtaacc tgtcctctct ttacatcaga tggtccatgg cgagctactc
    25441 tgaaagctgg aaccttaatt gaagaggacc tctttgtaac aggaaacttt ggttctaagg
    25501 caccttacaa cttttcgcag atgcaggaat tctttgatga acatggtaag aaatggccac
    25561 tcatgtgtat ggagttctgg gatggttggt ttaatcgctg gaaagaaccg attatcacac
    25621 gggatcctaa ggaattggca gatgcagttc gagaggtttt ggaacaaggc tctatcaatc
    25681 tttacatgtt ccacggtggt acaaactttg gtttcatgaa tggttgctcg gctcgaggaa
    25741 ctttggacct gccacaagtt acgtcttatg attacgatgc ccttctggat gaagaaggaa
    25801 atccaactgc taaatatctt gcagtcaaga agatgatggc aacacatttt tcagagtatc
    25861 cgcagttgga accactctac aaagagagta tggagttgga tgctattcca ctagttgaaa
    25921 aagtttcttt gtttgaaacc ttagatagct tgtcaagtcc tgtagaaagt ctctatcctc
    25981 aaaagatgga ggagctggga caaagttatg gctacctact ttatcgaaca gaaacaaact
    26041 gggatgcaga agaagaaaga cttcgtatca ttgatggtcg agatagggcc cagctgtatg
    26101 tcgatggtca gtgggttaaa actcaatatc agacagagat tggggaagat attttttatc
    26161 aaggtaaaaa gaaagggcta tctaggttag atatcttgat agaaaatatg gggcgtgtca
    26221 actatgggca taagttctta gcggatacgc aacgtaaggg aattcggaca ggggtctgta
    26281 aggatctgca tttcttacta aactggaaac actatccact tccactagac aatcctgaga
    26341 aaattgattt ttcaaaagga tggactcaag gacaaccagc cttttacgct tatgacttta
    26401 cagtcgaaga gccaaaagat acttacctag acttgtctga gtttggtaag ggagttgcct
    26461 ttgtcaatgg gcagaatcta ggacgttttt ggaacgttgg cccaactctc tcactttata
    26521 tccctcatag ctatctcaag gaaggtgcca accgcatcat tatctttgaa acagaaggtc
    26581 aatataaaga agagattcat ttaactcgta aacctacact aaaacatata aagggggaaa
    26641 acttatgaca attgtaggat gccgtattga tggacgtttg atccacggac aagtagccaa
    26701 tctttgggct ggaaaactaa atgtttcacg cattatggtt gtagacgacg aagttgtcaa
    26761 caacgatatt gaaaagagtg gtttgaaact tgcgacacca ccaggtgtga aattgagtat
    26821 tttgccagtt gagaaagctg cagccaatat tcttgctggt aaatacgata gccaacgtct
    26881 ctttatcgtg gctcgtaaac cagaccgctt ccttggcttg gtagaagcag gtgtaccact
    26941 tgaaaccctt aatgttggga atatgtctca aacaccagaa actcgttcta ttacacgttc
    27001 tatcaacgta gtagacaagg atgtggaaga cttccacaaa ctggcagaaa aaggtgttaa
    27061 acttactgct cagatggttc caaatgatcc aatttcagac tttttgagct tattaaaata
    27121 ggaaaaaaat ttttaggagg tcattgttat gatacaatgg tggcaaattt tacttctcac
    27181 tttgtactca gcttatcaaa tctgtgatga gttgacgatc gtttcatctg caggttcccc
    27241 tgtatttgct ggtttcatta ctggtttaat catgggagat gtgactactg gtttacttat
    27301 cggtggtaac ttgcaactgt tcgttcttgg ggttggtacc ttcggtggtg cttctcgtat
    27361 cgacgcaact tctggtgcgg ttcttgcgac agccttctct gtttcacaag gaattgatgc
    27421 accgcttgcc attactacaa tcgctgtacc agtagcagct ctcttgactt acttcgacgt
    27481 tcttggtcgt atgactacta ccttcttcgc tcaccgtgtg gatgctgcaa tcgaacgctt
    27541 tgactataaa ggtattgaac gcaactactt gcttggtgcg attccgtggg ctctatctcg
    27601 tgcccttcca gtcttctttg cccttgcttt tggtggtgcc tttgtacaat cagtagtaga
    27661 cttcgttgaa gcctacaaat gggttgcaga tggcttgaca cttgcaggac gtatgcttcc
    27721 aggtcttgga tttgcaatct tgcttcgtta ccttccagtt aaacgtaacc ttcactacct
    27781 tgctatggga tttggtttga cagctatgtt gactgttctt tactcatatg taacaggtct
    27841 tggtggcgct gttgctggta tcgtaggtac tcttcctgct gaagttgctg aaaaaattgg
    27901 tttcgtgaac aacttcaaag gtttgtctat gattggtatt tctatcgtag gtattttcct
    27961 tgcagtgctt cacttcaaaa atagccaaaa agtagctgta gcagcacctt ctacaccatc
    28021 agaaagtggg gaaatcgaag atgacgaatt ctaattacaa acttacaaaa gaagatttta
    28081 atcaaatcaa caaacgtagc ttgtttactt tccaattagg ttggaactac gaacgtatgc
    28141 aagcttctgg ttacctttac atgatcttgc ctcagttgcg taaaatgtat ggtgatggaa
    28201 ctcctgaatt gaaagaaatg atgaaagttc atactcaatt cttcaatact tcaccattct
    28261 tccataccat tatcgctggt tttgaccttg ccatggaaga aaaagatggt gtaggttcaa
    28321 aagacgctgt taacggtatc aagacaggtt tgatgggacc attcgctcct cttggggata
    28381 caatctttgg ttcacttgta cctgctatca tggggtcagt cgcagcaact atggctatcg
    28441 ctggccaacc ttgggggatc ttcctttgga ttgcagttgc agtagcgtat gacatcttcc
    28501 gttggaaaca gttggaattt gcttacaaag aaggggttaa ccttatcaac aacatgcaaa
    28561 gtaccttgac agctttgatt gacgctgcat ctgtacttgg tgtcttcatg atgggtgctc
    28621 ttgtagcaac agtgattaac tttgaaattt cttacaagtt gccaatcggt gaaaagatga
    28681 ttgatttcca agacatcttg aaccaaatct tcccacgttt gcttccagca atctttactg
    28741 cctttatctt ctggttgctt ggtaagaaag gtatgaactc tactaaagct atcggtatta
    28801 ttatcgtact tgctttggct ctttctgccc ttggtcactt tgcacttgga atgtaattcc
    28861 ttatgactaa atcattaatt ttggtgagcc atggtcgctt ctgtgaggag cttagaggta
    28921 gcacagaaat gattatgggc ccacaagaca acatttacac agtagctctt cttccagaag
    28981 atggcccaga agaatttact gctaaatttg aagctgttat tgaaggattg gatgatttcc
    29041 tagtttttgc ggatcttctc ggtgggacac cttgtaatgt ggtgagtcgc ttgatcatgg
    29101 aaggtcgtga tattgacctt tacgcaggga tgaatcttcc aatggtgatt gaatttatca
    29161 atgcgagcct tacaggcgca gatgcggact acaagagccg tgctgcagaa agcattgtga
    29221 aagttaatga cctgttagcg ggcttcgatg atgacgaaga tgaataatac tcttcgaaaa
    29281 tctcttcaaa ctacgtcaac gtcgccttac cgtaggtata tgttactgac ttcgtcagtc
    29341 ttatccggca acctcaaaac ggtgttttga gctgacttcg tcagtcttat ccggcaacct
    29401 caaagcagtg ctttgagcag cctgcggcta gtttcctaca gattttagtt ggaactcgat
    29461 tcaattcatg tgacaacgtg aaaatcgtta gagcatttta tatagaatat acatgggaat
    29521 ggagcttact cccattccta tatttaatag aaaaagagga actcaatgct acattataca
    29581 aaagaagact tgctcgaatt gggtgcagaa atcactacgc gtgaaatcta ccaacagcct
    29641 gatgtatgga gagaagcttt tgaattttat caagcaaaac gtgaagaaat tgcagccttc
    29701 ctacaagaaa tcgctgataa acatgactat attaaggtta tcttgacagg tgctgggact
    29761 tctgcttatg tgggagacac cttgctacct tactttaagg aagtctatga cgaacgcaaa
    29821 tggaatttca atgctattgc gacaacagat atcgttgcca atccagcaac ctatttgaaa
    29881 aaagatgtgg caactatcct tgtgtctttt gctcgtagtg ggaactcgcc tgaaagtgtg
    29941 gcgactgttg atttggccaa atccttggtg gatgagcttt atcaagtgac gattacttgt
    30001 gcaacagatg gtaaattggc tcttcaagct cacggtgatg accgtaatct cttgctcttg
    30061 caaccagctg tctctaatga tgctggattt gccatgactt ctagctttac gtctatgatg
    30121 ttgacagctc tcttggtctt tgatcctaca gaatttgctg ttaagtctga acgttttgaa
    30181 gttgtatcta gtcttgcccg taaagtttta gacaaggcag aagatgtcaa agagctcgtt
    30241 gatttagact ttaaccgtgt catctatcta ggcgctggtc ctttctttgg acttgctcat
    30301 gaagctcagc tcaagatttt ggaattaact gctggtcaag ttgcgaccat gtatgaaagc
    30361 ccagttggct tccgtcacgg tccaaaatct cttatcaacg acaatacagt tgttttggtc
    30421 tttggtacaa cgacagacta cactcgtaag tacgacttgg acttggttcg tgaagttgct
    30481 ggtgaccaga ttgctcgtcg tgttgtgctt ttgagtgatc aagcttttgg tcttgaaaat
    30541 gtcaaagaag tggcccttgg ttgtggcggt gtcttgaatg atatttaccg tgtcttccct
    30601 tacatcgttt atgcccaact ctttgcccta ttgacttcac tcaaggtaga aaataaacca
    30661 gatacaccgt ctcctacagg tacagtaaac cgtgtagtac aaggtgtcat aattcacgaa
    30721 tattaaaagt aagacagtgt ttatgaattc ttgacaagag gatttgtaaa ttatcagata
    30781 aaccatagat tgtcagtacg ctttctatgg tttgtttgct tgagagaaat agtaaaagga
    30841 gaacagaatg aaagcataca cagagcgtgt atttggaaat gttgagggcg aggatgtctt
    30901 ggcctatcga tttgagacag acggtggcta ccaacttgag gttatgactt atggcgcgac
    30961 catcttgcgc tatgtcgcac ctgacaaggc tggaaatttt gccaatgtta tcttgggatt
    31021 tgatgacttt gatagttatg taggcaatag tcccaagcat ggagcaagtg taggtcctgt
    31081 agcgggtcgt attgcaggtg cgacctttga gctcaatggt aagacctatg accttgaggt
    31141 taataatgct agcaactgta atcacagtgg ttcaactggt tgggattcca gcttgtttga
    31201 agttgaagaa gtaagcgatc atggcttgac tctctacaca gaacgtacag atgggacagg
    31261 agggttccct ggaaatctca agatttggat cagttatcac ttggaagaaa ctggtgccta
    31321 tgaaattagc tacaaggtaa cgaccgatca ggatacgctg gtcaatccaa ccaaccacag
    31381 ctatttcaac ttgtctggtg atttcacgca gacgattgac cgtcatgtct tccaactaaa
    31441 cacagagggc atttactcaa tcactcctga cggtgttcct gccaaaactc cagaagccaa
    31501 ccgtgatgtg gtcaaacaca tctacaatgg taccttgttg aaggatatct ttgcagaaga
    31561 agatgagcaa atccagctgg catcaggttt ggatcaccca tttgcccttc ctgtaggcca
    31621 tgacaatgct ggattccttt atgaccaaaa ttcaggtcgc ttcctgcttt tcaagacaga
    31681 agctccttgc tttgtggtct acacagcaaa ctttgtggat gaaagtgtca tcataggagg
    31741 tcagccaatg ctacagcaca atgggattgc tcttgaagcg caagctttac cagatgccat
    31801 tcacagtgac cttaaaggcc aagtcattct taaagctggt caaaccttca ccagtaagac
    31861 acgttatgaa cttgttgtga aataaaaaag ctggtcaaaa agtctttaaa attaaaataa
    31921 cgcatattgt caggtgatga aaagtttgat actatgcgtt ttattatgaa atgatttact
    31981 ttatcttatc ctgaaatggt gttatttttg agttatctgg cttgactttc ttgatggaaa
    32041 ttatataata gttgtaataa caataattac aacgagaaaa gaggaccatt tatgacctat
    32101 gaatacaaga gtcacattta tttggcagag acagttttaa atgtaaagga tttggccagt
    32161 caaacagcct tttatcagca agttattggt ttagaaatct tatctcaaac tgagacagag
    32221 tccattctag gccttggtgg aaaagtcttg gtacagctga ttcaagcaca agagagcgga
    32281 gaagtgaggg aacattatgg tctttaccat ttggccattc tcttgcccac acgcaaggct
    32341 ttggctgatg tcttgaaaca cctgacagat ttacagattc ctcttgtcgg cggtgcagac
    32401 catggttaca gtgaagctat ttacttggaa gatttggagg gaaatggcat tgaactctat
    32461 cgagataagc cagtttccac atgggatatt cgagaagatg gacgcattat cggagtgacg
    32521 gaggctcttg cggcgcagga catttatgag ttgggggaaa gagtagagcc ctttatcctg
    32581 gcagaaggta caagaatggg gcatattcat ctttccgtca aggatagtcg aaagtccagc
    32641 cagttttatc aaaaggtgtt agggctagag gataaattca gtgtgcctag cgctagttgg
    32701 attgcggctg gagattacca tcatcattta gcagttaacg aatggggagg aaaaggtctg
    32761 gcttcgcgta agcaaggctt accaggttta gcctactatg tcatcgaagt cgcacataaa
    32821 gaagaactgt taacgattgt ccaacgagca caagaagttg acgcaccaat caaatggatg
    32881 acatcgagcc aattggaaat cacagactca gatggcatcg tgacccgtat tcgtttagca
    32941 aggtaaaatt aggaatttct aataagttat aagtattgct agtttgcttt ttgaacggtc
    33001 tttggtaaca gaactgcgtg agctggatgg gtgagaattt tgacaaagaa gctgattaga
    33061 gatataatga agaaaaatcg agcaaggaaa aagaaatgac aaattcaaag tatattactt
    33121 gtttgaaacg ttcagagggc cagttgtgtg ggattcaaaa gatgattgaa ggagatcgtg
    33181 actgtgctga tattgtgacg caactgacag cagtgagatc tagtgtagag cgcgtgattg
    33241 agatgataat taccgaaaat cttactgaat gtatcaatca gccactagat gattctgaag
    33301 ctcaaaagga acgcctagaa aaggctatcc gatacttgat taaacggaaa taaatgaatg
    33361 ttttgagacg atatgtgcaa aggtctatta actattagaa tagtttaatg tgagtcaaaa
    33421 gaagttgtaa aaaatcttta aaattaaaaa aacgcatagt atcaggtgtt gaatgtactg
    33481 acccccaaaa gttagatttt ttctgtctaa cttttggggg tcagttcata agaaccttgg
    33541 taatatgcgt tttattatgt agaaacttat actcttcgaa aatctcttca aaccacatca
    33601 gcttcacctt gccgtagata tggttactga cttcgtcagt tctatccaca acctcaaaac
    33661 agtgttttga gctgacttcg tcagttccat ccacaacctt aaaacagtgt tttgagcagc
    33721 ctgcggctaa cttcctagtt tgcactttaa ttttcattga gtattacttc atcttctcat
    33781 gaaattgagt ttttgcccag ctcctcttga ttattctact tgaccgggcc aagtattcat
    33841 accaccttct acgttggtaa cggtgaggcc ttgggagctg agaaattggc aggtagatgc
    33901 agagcggact cctccttgac aaataacata gtattcatgg tcaggtttga gttctttgta
    33961 gccttgctct aaggtactta atggaagatt tttggcacct ggtgcatgtc ctgcttggaa
    34021 ttcatgtgct tcacggacat cgataagttc tagattttca ttttagtatt ttccataaaa
    34081 gtcagccatg ctgatactag tttccatatt ctactccttc tgggttagcc attttgtata
    34141 gtgaataagc gccgtcaagg ttttggacgg taaatcctgc ttgcttgagg ataggctctg
    34201 cgatatagct gcgcaaacca ctgtggcagc tgacgatgta ggcttgtttt ttgtccagtt
    34261 catcagcttc ctccttgaca ctttgtcagt ttttgataca atagtacaaa attagaggag
    34321 gtgggctatg attcagaaac atgcgattcc cattttagag tttgatgata atcctcaggc
    34381 ggttatcatg cccaatcacg aggggttgga tttgcagttg ccaaagaagt gtgtctatgc
    34441 ttttttaggt gaggagattg accgctatgc gagggaagta ggggcgaact gtgttggcga
    34501 attcgtttct gctaccaaga cctatccagt ctatgtcatc aactacaagg gtgaggaggt
    34561 ctgtctggct caggctcctg ttggctccgc tccagcagcc cagtttatgg attggttgat
    34621 tggctatggt gtggagcaga ttatctctac tgggacctgt ggtgtcctag ctgatataga
    34681 ggaaaatgcc tttctagtcc ctgttcgcgc tttgcgagat gagggagcca gttaccacta
    34741 tgtggcacct tgtcgttata tggaaatgca gccagaggct attgctgcta ttgaggaagt
    34801 tttggaagac agagggattc cttatgaaga agtcatgacc tggacgacag acggttttta
    34861 ccgagaaacg gctgaaaagg tggcttatcg taaggaagaa ggctgtgctg ttgtggagat
    34921 ggagtgttct gctcttgcgg cagtagctca attgcgtggg gttctctggg gtgaattgtt
    34981 gttcacagca gattctctag cggacttgga ccagtacgac agtcgtgact ggggctcgga
    35041 agcttttaat aaggcgctag aactgagttt agcaagtgtt caccaccttt agttgtacag
    35101 gcaaaggatt tgttttatca taaaatgtct agctcatact tttcaaaaat atgtttaaac
    35161 gaggtcacct tcctcttgtc ctaggcatgt tgaggttggg aaaaatcttt aaaatcagaa
    35221 aaacgtatca tatcaggtga tgaaaatttt gatactatgc gttttatgtt ggtaagattt
    35281 agagtgagat gaaatgatac tcttcgaaaa tctcttcaaa ccaggtcagc ttcaccttgc
    35341 cgtaggtata tgttactgac ttcgtcagtc ttatccggca acctcaaaac ggtgttttga
    35401 gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag
    35461 ctttctaagc gatgccttgg ttctcattgc ctataatcaa aaagagaaat tttctcctga
    35521 aaagcatata gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac
    35581 atctatcaag tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg
    35641 gtgttagtga attttgcctt atcctatcta agtcatttcg agctttttat ggtacaatgg
    35701 aaacatgtta ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc
    35761 agcccgtcgt atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag
    35821 cttgcccttt gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc
    35881 tgtctctgca gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat
    35941 ctggggccaa ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacttt
    36001 tattggggtt ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat
    36061 tcaggatagt tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt
    36121 tctcacgacc tttttggttg agagcttggg agctattttg cttagttttc gccttattcc
    36181 tcaacttggc tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg
    36241 taatgccggt tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact
    36301 ggtcaatctg gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt
    36361 tgatttggct ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct
    36421 tgtactattg ttgactatag gtttgttgtt atttggaacg gcaactactc tctttcttga
    36481 gtggaacaat gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt
    36541 ttttcaaaca gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca
    36601 tcctgtgact cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac
    36661 agctggggga ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct
    36721 tctaggcttg cctcatgcca atgttgcgag acgaacgatt gcgtcgcgaa cggttcaaaa
    36781 atcctttagt gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg
    36841 gataacagcc aaaggcaatc ctccctttat ccacctcata tttgaaacca tttcagctct
    36901 tagtacagtt ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt
    36961 tatcatgcca cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc
    37021 agattaccat ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg
    37081 ttaagaaagg aaagagcatg tcagatcgta cgattggaat tttgggtttg ggaatttttg
    37141 ggagcagtgt cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc
    37201 acgcagagcg catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca
    37261 cagatgaaga attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga
    37321 caggtgaaaa tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac
    37381 cgactgttat tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag
    37441 ctgactcggt tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt
    37501 tccataatag tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa
    37561 ttcctcagtc ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc
    37621 tgaatatttt gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag
    37681 atgacctctt gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata
    37741 ccctagtagc attgaattcg taaagaggga tgacccctct tttttgatgc ccaagatggc
    37801 aaatagagac agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg
    37861 taaaatagaa ggaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag
    37921 gaaactagct gcgggctgct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt
    37981 cagctcaaaa cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac
    38041 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc
    38101 ccctaaagga gcagattatg aagttattgt ctatcgccat ttctagctat aatgcagcag
    38161 cctatcttca ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga
    38221 ttatcaatga cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt
    38281 atcctaatat cgttagagcc atctatcagg aaaataaatg ccatggcggt gcggtcaatc
    38341 gtggcttggc agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg
    38401 atcctcgtgc ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag
    38461 aggtggatgt ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga
    38521 gtatgagtta cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa
    38581 atttctccaa aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc
    38641 gtgctagcca gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta
    38701 cgccccttca gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga
    38761 ttgggcgtga ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac
    38821 tcaaggtcaa tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa
    38881 tgcgagaata tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca
    38941 accgatctgg aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc
    39001 agaaaaatcc agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac
    39061 attctgtctt gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt
    39121 atggatttaa ttaatataag tgttttataa gagggattta agaaaaattt taactttttc
    39181 ttagtccttt ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag
    39241 gagaatccta tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc
    39301 agtgtcggtg ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca
    39361 agttctgtac gtgccgatgg gctcaatcca accccaggtc aagtcttacc tgaagagaca
    39421 ccgggaacga aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg
    39481 aaacctgagg gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa
    39541 gtgagcgagg aaacaagccc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct
    39601 caaaaaaatc cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat
    39661 gggacacaag caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa
    39721 aatacaaaag acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt
    39781 cctttcactg ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg
    39841 ttaactcgtc tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct
    39901 aaaaatcctg ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta
    39961 gacttaaatg gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct
    40021 aatggtactc aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct
    40081 gacttgacta atctagttgc tactaaaaat gtagacatca acatcaatgg attagttgct
    40141 aaagaaacag ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca
    40201 gcctacctag aaaaagccaa gggtgaaggt ccattcacag caggtgtcaa ccatgtgatt
    40261 ccatacgaac tcttcgcagg tgatggcatg ttgactcgtc tcttgctcaa ggcatctgac
    40321 aaggcaccat ggtcagataa cggcgacgct aaaaacccag ccctatctcc actagg
//
LOCUS       DBERAE010000014        38440 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.14, whole genome shotgun sequence.
ACCESSION   DBERAE010000014 DBERAE010000000
VERSION     DBERAE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 38440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.14"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(372..521)
                     /locus_tag="ACL70N_000909"
     CDS             complement(372..521)
                     /locus_tag="ACL70N_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGS0589730.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            486..605
                     /locus_tag="ACL70N_000910"
     CDS             486..605
                     /locus_tag="ACL70N_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGS0589731.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL70N_000911"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL70N_000911"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGS0589732.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL70N_000912"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL70N_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGS0589733.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="ACL70N_000913"
     CDS             complement(2517..3044)
                     /locus_tag="ACL70N_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS0589734.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL70N_000914"
     CDS             complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL70N_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGS0589735.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9376)
                     /locus_tag="ACL70N_000915"
     CDS             complement(4466..9376)
                     /locus_tag="ACL70N_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGS0589736.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGKWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVYENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            9669..11300
                     /locus_tag="ACL70N_000916"
     CDS             9669..11300
                     /locus_tag="ACL70N_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGS0589737.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11859..13466)
                     /locus_tag="ACL70N_000917"
     CDS             complement(11859..13466)
                     /locus_tag="ACL70N_000917"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGS0589738.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13856..14443)
                     /gene="rpoE"
                     /locus_tag="ACL70N_000918"
     CDS             complement(13856..14443)
                     /gene="rpoE"
                     /locus_tag="ACL70N_000918"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGS0589739.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14571..14882)
                     /locus_tag="ACL70N_000919"
                     /pseudo
     CDS             complement(14571..14882)
                     /locus_tag="ACL70N_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
     gene            complement(14780..15196)
                     /locus_tag="ACL70N_000920"
     CDS             complement(14780..15196)
                     /locus_tag="ACL70N_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589740.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            complement(15224..15874)
                     /locus_tag="ACL70N_000921"
     CDS             complement(15224..15874)
                     /locus_tag="ACL70N_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS0589741.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(15864..16427)
                     /locus_tag="ACL70N_000922"
     CDS             complement(15864..16427)
                     /locus_tag="ACL70N_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0589742.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16592..16826)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16880..17383)
                     /locus_tag="ACL70N_000923"
     CDS             complement(16880..17383)
                     /locus_tag="ACL70N_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGS0589743.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17576..18406)
                     /locus_tag="ACL70N_000924"
     CDS             complement(17576..18406)
                     /locus_tag="ACL70N_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0589744.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18391..20073)
                     /locus_tag="ACL70N_000925"
     CDS             complement(18391..20073)
                     /locus_tag="ACL70N_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589745.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20184..20432)
                     /locus_tag="ACL70N_000926"
     CDS             complement(20184..20432)
                     /locus_tag="ACL70N_000926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589746.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(20439..20987)
                     /locus_tag="ACL70N_000927"
     CDS             complement(20439..20987)
                     /locus_tag="ACL70N_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGS0589747.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21002..21850)
                     /locus_tag="ACL70N_000928"
     CDS             complement(21002..21850)
                     /locus_tag="ACL70N_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGS0589748.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22038..23387
                     /gene="trkA"
                     /locus_tag="ACL70N_000929"
     CDS             22038..23387
                     /gene="trkA"
                     /locus_tag="ACL70N_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGS0589749.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIETKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23391..24830
                     /locus_tag="ACL70N_000930"
     CDS             23391..24830
                     /locus_tag="ACL70N_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS0589750.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(24955..26634)
                     /locus_tag="ACL70N_000931"
     CDS             complement(24955..26634)
                     /locus_tag="ACL70N_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS0589751.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(26704..28116)
                     /gene="lacG"
                     /locus_tag="ACL70N_000932"
     CDS             complement(26704..28116)
                     /gene="lacG"
                     /locus_tag="ACL70N_000932"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS0589752.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(28126..28470)
                     /locus_tag="ACL70N_000933"
     CDS             complement(28126..28470)
                     /locus_tag="ACL70N_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0589753.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(28638..30524)
                     /locus_tag="ACL70N_000934"
     CDS             complement(28638..30524)
                     /locus_tag="ACL70N_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGS0589754.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRNYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWKNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(30526..31848)
                     /locus_tag="ACL70N_000935"
     CDS             complement(30526..31848)
                     /locus_tag="ACL70N_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0589755.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            32016..33239
                     /locus_tag="ACL70N_000936"
     CDS             32016..33239
                     /locus_tag="ACL70N_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS0589756.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            34671..34955
                     /locus_tag="ACL70N_000937"
     CDS             34671..34955
                     /locus_tag="ACL70N_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589757.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            34948..35196
                     /locus_tag="ACL70N_000938"
     CDS             34948..35196
                     /locus_tag="ACL70N_000938"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589758.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLHATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            35292..35510
                     /locus_tag="ACL70N_000939"
     CDS             35292..35510
                     /locus_tag="ACL70N_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589759.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LESFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(35878..38202)
                     /gene="pflB"
                     /locus_tag="ACL70N_000940"
     CDS             complement(35878..38202)
                     /gene="pflB"
                     /locus_tag="ACL70N_000940"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGS0589760.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT        11674 a         8220 c         6747 g        11799 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt cagaattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttgattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtgtagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aatgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatgacagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 atccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagt ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtataaaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattgataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaacgt ttctgataca cgcacaaaca cgtacgaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcaaggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 cataaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagta ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactttgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtgt ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 ccaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcgt aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgcaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgaa cctcacctgt taagcgatca agttctgtct
     5521 tttcttcctt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaaa gcttctttta cttctggtga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tctgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagttga cttcatgacc ttggtaacga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcgtct tggccagtga cagtcactga caaattagca tttactggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcga
     6421 gtggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttgcc acggacttcc ttagctagct
     6721 tccacttacc atctgcatct ttataataaa ggtcaaagtc tttggtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gcccctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttct gtatctggga
     6961 aggtacttcc gataacagta gcccctggaa cgatgttttc tgctagaggt cttggaagac
     7021 ttgtgtcttg gacagtcatc ccccactcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc taggttaaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cccgctagtg
     7441 agctaagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctggagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgatct gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttgacca gtagggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcatac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata cttggccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaattg gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttctgct gctggcttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacctgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgccttt tctagcttgt tttctctagc atgttcccct tcattctgct
     9181 tatcagcttc attggtcgaa tgctcactct ctcctgaaac aagctctgta ttagctccgc
     9241 tattttcagg aactgcagtt tcttcagcca aggctggacc agcaaataaa acagcaccaa
     9301 tcatcagcga gcaggctcct actgataact tacgaatact gtaacgacaa cgtctttcaa
     9361 aaaatggatt cttcattttc tcctcctaaa agattgattt tgttgtttta aagaaagcgc
     9421 tttatattct gtagtttttt atcaaactct agaaccatga taatcacatt tttatcctaa
     9481 aacattttta gacaaaaaac aataactgtt tgcacaaatc taaaataagg ttaaaaactc
     9541 ttaaaaataa tacacttatc aattataatt ttcttttaca aacttgacat taacacttgt
     9601 tagatttact tttatccttt aaaatagaat aggagatatt ccgcgattat ttttcggagg
     9661 aaaaagaaat gtccattaat tggcaggaaa ttttatttca ctttttaggt ggtctggggc
     9721 tattcttata tagcatcaag accatgggag acggtttgca acaagctgct ggagatcgcc
     9781 ttcgttttta cattgacaaa tatactagta atcctttctt tggagttctg gttggtattg
     9841 ggatgactgc tctaattcag tctagttctg gtgtaacagt tattacagtc ggcctggtca
     9901 gtgccggtct cttaacctta cgtcaggcta tcgggattgt catgggtgct aatattggga
     9961 caactgtcac atcctttctc atcggtttta aattaggtaa ctatgcccta cctatgctct
    10021 ttatcggtgc cgtctgtctc ttttttacga aaaatcggac agtcaataat atcggacgca
    10081 tcctctttgg tgtcggtggt atcttttttg ccctcaatct catgagcggc gcaatggctc
    10141 cactcaagga tttacaggtc tttaaggact atatgattga gctaagtaag aatcctgttt
    10201 tgggtgtctt tgtcggtacc ggcttgacct tgctaattca agcttcttcg gctaccattg
    10261 ggattttaca aaacctctac gccggcaatc taattgacct acagggagct ttgccagttc
    10321 tatttggtga caatatcggg acaaccatta cagccatcat tgcctcttta ggggctaata
    10381 ttgcagctaa acgggtagca ggagctcatg ttgccttcaa cgttatcgga acagtcgtct
    10441 gcgttatttt tctagttcct tttactgtcc tgattcattg gtttgaagct acgctaaatc
    10501 tagcaccgga aatgaccatc gcctttgctc acggaacctt taatattacc aacaccattg
    10561 tccaatttcc atttatcgga gctctggctt actttgtaac caagattatt cctggagagg
    10621 acgaggttgt caaatacgaa cccttatatc ttgatgaaca tttcatcaaa caagccccat
    10681 ctatcgctct aggaaatgct aaaaaagagc tcttgcactt aggaaactac gctgctaaag
    10741 cctttgacct ttcctataag tacatcattg acttggatga aaaagttgct gaaaaagggc
    10801 ataaaaccga agaagcaatt aacaccatcg atgagcaatt aacacgttat ctcattgccc
    10861 tttcaagcga agctctcagc caaaaagaaa gtgaagtgct caccaatatc cttgattcct
    10921 cccgtgattt ggaacggatt ggagaccaca cggaggctct actcaatctg actgactatc
    10981 ttcaacggaa aaatgttgaa ttttctgatg ccgccttgaa agaattagag gaagtttacc
    11041 gccaaactag tgactttatc aaagatgctc tggatagtgt ggaaaacaat gatattgaaa
    11101 aagcacgcag tcttgtagaa cgtcatgaag caatcaataa gatagaacgt gttctcagaa
    11161 aaacccacat caaacgcctc aacaaaggcg aatgttcaac acaagctggg gtcaacttta
    11221 tcgacatcat ctcacactac actcgtgtat cagaccacgc tatgaacctt gctgaaaagg
    11281 tttttgcaga acaaatctaa gaaccaagaa gctatccatc ataattggat ggcttcttac
    11341 tttttcctaa gcaagactag gctgaatgaa actgaaagag tattctgcag atatatagta
    11401 tattgaaact agaatagtac acctctattt ctaaaacatt gttagaaatc gatttgactg
    11461 tcctgatcga tttgtcctgt tattatttca ttttactata gtggattaaa ttaaaaaagt
    11521 ataatgtatt gaatctataa cagtacatct tgactgctaa aatatttcta taaattaatt
    11581 tgactttcct tatagagatg ttcacatctt atttcaattc atgatacaat ccagttccta
    11641 aaactttgct agaaattaat ttggctttcc gaattaattt gttcagattt tatttcattt
    11701 caatatactg ataaatccat tcactagcac agggcaagag ggagtcgcta ttgatttcaa
    11761 cggtagcagg tacatacaga ggactcctac ctcagatata ctgcaatatc atcgtatgca
    11821 aaaaacctct gagatttttc tcaaaggttc tgattttgct aattgctgtt ctcaaccgct
    11881 gcagtaacaa aggcagtgta gagttcttct ggtcggtttg gacggcttga cagttcaggg
    11941 tgatactgac aagctacaaa gaatttattt tcaggaattt ccacgatttc taccaaacga
    12001 ttgtctggag aaactcctga aaagacaaaa cctgctgcct caaactgctc acggaaggca
    12061 ttattaaact cataacggtg acggtgacgg cgttgcacca cttcttgatt gtgataagca
    12121 gcagcagcct tagagccacg tttcaactta gacggataaa gtcccaaacg aagggttcca
    12181 cccatatcct caatatcaat ctgatcacgc atgatatcaa tgatagggta ttttgtttct
    12241 ggtgcaagct ctgcagaatt ggcaccttca agacctaaaa cgtgacgagc aaactcgata
    12301 catgtcaact gcattcccaa gcagactccc aacattggaa catcattttc acgcgcatag
    12361 cggatggctt ggattttccc ttctgtacca cgttgaccaa aaccacctgg tacgatgatc
    12421 ccgtccgcat cagacaagag ttctgctaca ttctctgctg tcacatcatt ggcattgacc
    12481 caattgattt taacttctgc atcattgaca tagccagagt gtttcaaggc ttcgaccact
    12541 gagatatagg catcttgcaa ctccacatac ttaccaacaa gggaaatctt aacttgtttc
    12601 ttgaggttca tgaccttgtc caccatggct gaccattctg tcatagccgc tgctggtgcg
    12661 tctaatttca aatgatcaca aacaatttgg tccatccctt gtgcctgcaa gttcagtgga
    12721 atttggtaaa ggtgttcaac atccaacgat tcgataacgg cttctggtgc cacatcacag
    12781 aactgggcca gtttattttt aattccttga ccagctggct cttctgtacg aataaccaac
    12841 atatttggtt ggattcccaa gccacgcaat tctttgacag agtgttgggt tggtttggtt
    12901 ttcatttcac cagcagcctt gaggtaagga agcaaggttg tatggatata catgacatta
    12961 tccgcaccca catctgcctt catctgacga agagcctcta ggaatggcaa ggactcgata
    13021 tctcctactg ttccaccaac ctctgtgata atgacatcag agtcggtcgt tagagcggca
    13081 cgcttgattt tttctttcaa agcatctgtg atatgaggaa tgacttgaac agttgcccca
    13141 aggtattctc cacggcgttc tttacgaaga acttcactgt aaattttccc agttgtcacg
    13201 ttggaatatt tgttgagatt gatatcgatg aaacgttcat agtgacccaa gtccaaatct
    13261 gtctcagctc cgtcatctgt cacaaaaact tccccgtgct ggtaaggact catggttccc
    13321 ggatcaatat tgatataagg gtcaaacttt tgaatggtta ctttgagacc acgatttttc
    13381 aagagacggc ctagactcgc tgccacaatc cctttcccaa tagacgatac cacaccacca
    13441 gttacaaaaa tatatttcgt agacatagat tcctctttct aaaatgctca aggtcttgtt
    13501 aactacgagg ggatatagaa aacaagaccc tactaataag aataatctgg gacgactgca
    13561 ccagattcac aactaatact cttcgaaaat ctcttcaaac cgcgtcaacg tcgccttgcc
    13621 gtagatatgt gttcctgact ttgtcagtct tatctacaac ctcaaaacag tgttttgagc
    13681 agcctacggc tagtttccta gcttgctctt tgattttcat tgagtataaa atacaagaag
    13741 ataacttctt gaaaaaacaa aaatagctcc ctaagaacta gggagccccg acctctaaaa
    13801 gaggtgccca aacaatatga tacctaaaaa taggataatt gtcaatagct aactcttatt
    13861 cctcgctggt ttcagcgtcg tcatctgaaa actcgtcgtc gtcttcgttg agatccacat
    13921 cttctcccaa gtcatctgga gcgatttcgt tgatttctgc atcataagct tccacttcat
    13981 ttttttcatc atctggattt tcatcatcgt atgaaagagc tggatctgct tcgtatgcat
    14041 cttcgtcttc tggatcatct gcattgtagt caatggcatc tgaatcacca tccataaagg
    14101 cattgacacg ttttttctta gcttttggtg ctacttcatc gtcgtcattt tcttcaagag
    14161 cgatgatttc ttcgtcgatt tcgtccacac cataccatga acgaagaccc catttgttgt
    14221 ccccaagtga gatgaagcta ccgtcaaagt tcaactctgt gtagaacaga ggcaaagctt
    14281 cgcggatatc gctgtttgat gttccaaggt agttttgaat ttcgtttaca agatcgctaa
    14341 aatgcatctc atgatcgcga ccacgaagtt ctaatatagc acgcgctacc tcaatcatag
    14401 atagttcact tttttcttgc ccagcaaata cttctaattc caaagcgttt ctcctcattt
    14461 atactactat cgccagagcg aacagactct gacctcattt tatcatttac tctttatttt
    14521 acgataattt tgcggaatag tcaaaggtta agggggagaa agtggcagga ttagactaat
    14581 tccaatataa aactccttcc tttttctgtt gctccatttt ccacaaatcc aagcgacttg
    14641 aaacacctcc tagaagcatg attgtaggtg tagatttcct tgactctcaa ttctttccat
    14701 ccttttactc gagccaattc aatcaaagca cttagaatct tttttccaag tcctcgatgt
    14761 tggtaagcgg aattcccaat cacaatgggg agattatcct gagatagtgt aatatcccca
    14821 attggaaacc attctccctt ctccttgact tcaatccaaa aaagctcacc atgccgatcc
    14881 aaagaggtaa gatatgattt tttaaatcaa aaacagagta aatctttctt tcctcgcaag
    14941 cttgcgcata gagatgatat agttcatcac caccatctct atcccactca gcagaaatcg
    15001 tatcccgacc tgccaataaa gcctgataag ccctgtgatg cccatctgta atcagcaaac
    15061 aatctccaaa ggcaagaata ctgattggat cgacttggtt tgtttctgcc gactggtaaa
    15121 gcatctgaat atcttgcaac ttcttttctg ataaatatag ttgagtcgga tgaagatcta
    15181 ctatattgac tttcatttct ttctcctaaa gggaattcga tactcacttc tgtttgcctt
    15241 taaatcgcca ttggaagcgg agcttgtcat agaagggaaa ctcgataaac aagactccca
    15301 aacccacaca gaaactggca agaacatctg atgggtagtg aactcccaga tagactcttg
    15361 ataccagcac actgactagg tagaggccaa ggacgatttg tacgattttt ctccagacct
    15421 gatctttaat ccgctgacta agaataacaa tcaaagtccc taccatcagc gttacagcta
    15481 gagaatgccc acttgggaag gaaaatccct tctcctccac cagatgtaag atagctggtc
    15541 gtgggcgctg gtagatattt ttaaaggtca cgattaaaag acctgccaaa gccagatttc
    15601 ccagcatgaa gaaactttct atcttccatc gcttacgata aaagacaaaa gctataatga
    15661 caacccaagt gataatcact ggaatatcaa tcagatgtgt gagggatcga aaaagaatag
    15721 tcaaataatc tggtaagtct cctcgaatgg cagtctgaat cgattggtca aaaccgacca
    15781 gcgtttcagg gtaaaatttg accatatagc caagaataac gaaaagtaaa agggcaaaac
    15841 tgcccttcat taaaaatgtt tgtttatctt tcatagtgtt ttaaggttgg tttcaaaagg
    15901 acgtacaaca accagaatga aacggaaaag attacaccct caatcaagtt aaaaggtaat
    15961 accatggtca ttaggtagtt ggaaagtccc aaaatttttc caatatcaaa gttagcaaac
    16021 ttagcgtaca aaggaacagc ataaacatag ttgagaacca acatggccaa ggttaaacca
    16081 acagttccag ctagagagcc tagtaggaaa cgaagggttg tccgttcctt tttccaaatc
    16141 aaagcaaata cgatgacaaa aactcccaaa gctacgatat tcatcggcaa accaatgtaa
    16201 gtattcactc cttggctgtt aagaagcaat ttcaatagtg agcgaagcaa gagcactcct
    16261 agagcagcag gcaaatccat gaccaccaga cccacaagga ctggcaagat actaaattcg
    16321 atcttgagga aagatgccgc tggtaaaagc ggaaagtcaa agtacatcag cacaaatgag
    16381 atggctgata gaattgcaat ggtcgaaagt cgacgtgtgt ttgtcataac aggttcctcc
    16441 aattttctat aaaatcagaa gaagttggaa aggattcctc tatctattct cactttttat
    16501 atcccaaaag ttccctctta ctctattaaa gaaaaacaaa gcaagtggtt acaatccggc
    16561 tataaatcta tcaaaacaga caaagctatt ctttcgtctt ctcccatcca gactatactg
    16621 tcggttgtgg aatctcacca catcagcttg cgctcgcgga cttctttaaa gagaaggaaa
    16681 tagagatttt tcttttagac taggcgacaa gctgtaggca taacttctgg ttaggcaaag
    16741 cttgtcaaca aagtataaaa ggaaaagatc atttcctagt taaagtcacc gccggtcggg
    16801 aatcacaccc tgccctgaag actcttttat cataacaaaa aacgcttgca agcgcaagca
    16861 ttttgttcat tttcattttt tatttcaatt tatccacttc ataggtatgg acgagctcaa
    16921 gacctgcaaa gttctgctgg cgaagagcct catagacaat catgcagacg gtattagaca
    16981 cattgagact gcggacatgt tcatcattca tgggaatacg gagagccttc tcaggatgtt
    17041 ctcgcataaa atcttcaggt aagcccttgt cttcacgtcc aaagagaaaa taatggtcct
    17101 cgtcagtcga taaatccacc tcagaataga ctttttccgc gaatttcgaa atcagataga
    17161 gttttccctt catctgagat atgaaatctt ccaaactctc gtaaaaataa atctctagct
    17221 tatcccagta atccaatcca gcccgcttca tcttgcggtc atcaatagga aagcccatag
    17281 gcttgatgat gtggagggga gaattggtcg cagcgcaagt acgcgcgata ttgcccgtat
    17341 tttgtggaat ttgaggttca aataatacaa tgtgatttgt catgacttgc ttcctttcac
    17401 cattgcaaaa aaatagccac actgcccgga gtcaagctca gcaaacagcg tggttaaggc
    17461 atcgttaact tacctcacaa caggtttgaa gtaaatcagc gaaactactt tcttagtata
    17521 acactttcag aatcattgtc aatagaaatg acttgatttt ttcaattttt tcaagctatt
    17581 tccaagggtt gtaaaatcgt ccctgattct gcaagataag tagtaaacta actactaaaa
    17641 acaaggttgc caagagcaag gtaatatagt ctcctttttt caaggcctga taactatacc
    17701 atgtgcgttt tttctctttc ccaaagcggc gaagctccat ggcagtcgca atggtatcaa
    17761 tgcgttctag cgagctaaaa atcaagggcg taataatgag cagattgcct ttgattcgtt
    17821 gcataagaga agctttcttg gataattcca tcccacgcgc ctcctgagac atcttgatag
    17881 taaagaattc ttcctgcaaa tctggaatat agcgcaaggt caggctgaca gaataagcaa
    17941 tcttataggg cacaccaatt tgatttaaac tggaagcaaa ctgactagga tgggttgtca
    18001 tcaaaaagat aatagccaga ggaatggtgc aaagatactt aatggccaaa tttagcagat
    18061 aaaagagctc ctggctggtt agagtgtaga caccgattcc ctgccaaatc acacttctct
    18121 ctccataaag tccaacccca tactcgggag aaaagagata gaccatcaaa acgtttaaaa
    18181 cggcaaatac cgtcgcaaaa acggctacaa aggaaacatc tttaaagcga atttctgata
    18241 aatagaggag aaagactgaa aagatggcaa tcagcaagag cattctggta tcatagctaa
    18301 tcatggccgc caatgatacc agaatgaaaa agagaagttt cccagctcct gacaagcgat
    18361 gaatcacagt atctctatgc tggtaaccga ttaatttagc ttgcatccct ctctcctttc
    18421 tttgtaaaat gccgttaaat ccagtggatc cacatctagt ttcttagcca agttaaagat
    18481 ggaggtttct tttagattgg cttttactaa cagctcagga tcgctcaaca gactggctgg
    18541 aacagtatcg gcaatcaatt ctccatccac catgacaagg acccggtctg aataatccag
    18601 catcaattgc atatcatggg taatcatgac aatggtatgc cctttttgat gtaactcttc
    18661 gagaaattcc ataatctcag tatagttctt ctgatcttga cctgcagtcg gttcatctag
    18721 gagaataatt tcagctccta agaccaaaat tgaagcaatg gtgacacgtt ttttctgacc
    18781 aaatgacagg gcagaaatag gccaattacg gaattcataa agtccacaga ttttcaaggt
    18841 ttcatatact ctcgtttcaa tttccttctc atccacacct cgcaaacgga gccctagagc
    18901 cacctcatca aaaatcatat tggttgaaat catttgatta ggattttgta gcacatatcc
    18961 tactcgttcc gcccgctctg caacagaatc gccttttata tcctgttttt cccaaagata
    19021 gcgtccttcc gtctgaataa agctacttat agccttggct agagttgatt tccctgctcc
    19081 attttttccg acaatagcaa tcttttcacc ctttttaata tctaaatgta gggattttaa
    19141 aatcggtcta tcatcataag aaaaagatac ttcctctagt ctaaagagtg actgcaatgc
    19201 tggggtttct tttgccagtt cattctgcaa ctgaacctga ccttttgaga tagacaagtt
    19261 atccagattc gctaattgtt cttccttgac taaatccaca cccaattgac ggagagtggt
    19321 gagataaagg ggttcgcgaa ttccattttg ggtcaacaaa tcagtcgcca gtaactggtc
    19381 agggctccca ttaaaaagga tacgaccatc gtttatcaag acaatccgat ccacagggca
    19441 atgcagaaca tcctccaaac ggtgctcgat aataagggtc gtcgtcccct cctccttatg
    19501 aatctggtca atcaattcga taatatcctg acctgacttg ggatcaagat tggcgagtgg
    19561 ctcatcaaac aagagaatcg gactttcatc aatcaagaca ccagccagac tgactcgctg
    19621 cttttgtcca cctgacaaat cctgagggcg ctgatccagt aaaggaagaa ggtccagctt
    19681 ttcagcccat ttataaacac gacctttcat ctcatctagg gctgtcacat cattttccag
    19741 agcaaacgcc aaatcttctg ccacagacaa gccaataaac tgcccatctg tatcctgcaa
    19801 aactgtgcta accagatgag acttatcata gatgctcata tcaaaggctg tttgaccctt
    19861 tatcaaaaat tctccatatg tctgaccctt gtaaatattg ggaataatcc cattcaaaca
    19921 ctgacccaag gtagatttac ctgatccaga tggtccaaca attaagactt tctctccctt
    19981 gtaaatggtc aagtctatcc cttgcaaggt cggttcttgt tgtgtttcat accggaaaga
    20041 gaaatccttc cactcaatta tagcttcttt catcttactc tcttcattcg cttcttagac
    20101 ttctatttta tcataaatca agcccttctt gcagtctctc ctattaaaat cttagcgcca
    20161 aaaagattcc tatcctagct tacttaccta actaatctat aaacatcgaa aaagactagt
    20221 tgcccagcct tccccatcat tttatactct tcgaaaatct cttcaaacca cgtcagcttc
    20281 gccttgccgt aggtatggtt actgacttcg tcagtttcat ctacaacctc aaaaccatgt
    20341 tttgagctga cttcgtcagt tctatccaca atttcaaaac actgttttga gcaacctgcg
    20401 gctaacttcc tagtttgctc tttgattttc attgagtatt agtccttttt caaacttcct
    20461 gcacgagttt gggttcctgc ataggcaagt aagagaagag ttcctgcaat agctacagat
    20521 acaccattgg caattcccgc aacaatccct tgtgcaaata ctttttctgc cgcttcttga
    20581 taaatcacaa catctccaag tggtgccaag acaccccaaa caagggcatt tgcaagtagt
    20641 tgaatgaggt taaaaataag aatatctttc cagtcaaaaa caccattgat cacgcgaacg
    20701 tactttctaa aaagtcccac aactaaacca aagagtccgc tagcgataat ccaagtccac
    20761 catagaccat aaccagcaag agagtccttg attgcatgac caatcaaccc gacaagcaaa
    20821 ccgataatcg gtccaaaaat aatagaaagt agcgcttgta ccgcatactg aagctggatg
    20881 cttgtatttg gaacaggggt tggaatgttg atcatcccga tgacgacaaa gagggcagcg
    20941 ccaattccga cagcaacaac ttgtttaatt gtaaatttaa tttccatact attctcctat
    21001 tttatccttc tattttcttt atttcaatgg tccaagatga accgacacct acattatagg
    21061 ccttggcaaa ggaaccttgg ttgatagcca aacctaaacg atagagagag ttgatgtaaa
    21121 ggatgggttg cccaattctc acatctgcaa atgatttgcc atagacaacc tgattttgat
    21181 agaccagcat atcagcatga tagatggtca cttcaaaacg atcaccaaat tctggttcca
    21241 gcttgtaaaa ttcttcccgt gtgatagagg tccaaagcga accgaaacgc acatccagaa
    21301 tatcaatggc tcccttcacc agatgatctt ctatgatggt cgctacgact ggaagctcta
    21361 caatctgttc cacactgagc tctggcccta cttcctcaaa agtaatgtga ccactggcca
    21421 gtttagcacc agtataggca tagacatcac gaccgtggaa ggtataagaa tgctctgtgt
    21481 tttgacgcct attggccacc tcagaaatct cacgaatggc tacaatgcca acgtgtttct
    21541 tgataaagga aagcgtccca ttatctggcg tgacaatgta ttgatttttt gcagtcttgg
    21601 caactacact cttacgtttc gaaccgacac ctggatcgac aaccgataca aacgtcgttc
    21661 cctcaggcca gtaatccacc gtctgaaaga gacgatagct cccctcaaaa atattataag
    21721 gcgtgatatc gtgcgtcaag tgatggattt ttaaggttgg agactcttct aaagccactc
    21781 caatcatagc cgataccgca ccatcaacca gaccaaagtc tgattgtaat accagtaaat
    21841 tattattcat tttatctcct tgtatatcct ttatcatacc atatttcaga gaaagtcgct
    21901 aatagctatt tcaattggtt agggtatagt tttaccttat agcgaatttt cactaaaagc
    21961 tcttgttatt agctagtagg tgcatttttt cttgaaaaag ggtatgatag ttacatcatg
    22021 aaaaagtagg ttttattatg aaaattatcc ttgtcggagg gggaaaagtt ggttttgccc
    22081 tctgtcgctc cttggttgca gaaaagcatg atgttttgct gattgagcaa gacgaagctg
    22141 ttctcaatca tattgtcagt cgctttgata tcattggtat ccttggtaac ggggccgatt
    22201 ttgccattct tgagcaagcc agcgtccaag attgtgatat ctttatcgcc ctgactgagc
    22261 acgatgaagt caacatgatt gcagcagttc tagccaagaa aatgggagct aaagaaacta
    22321 tcgttcgggt gcggaaccct gaatattcta actcttattt caaggaaaag aatattctcg
    22381 gtttttctct tatcgttaat cctgagctct tggctgcccg cgctatcgcg aatatcattg
    22441 acttccccaa cgccctgtct gtcgaacgct ttgctggtgg acgcgttagc ctcatggaat
    22501 ttgtcgtcaa gtccaccagc ggtctttgcc aaatgcccat ttctgatttt cgtaaaaaat
    22561 ttggtaatgt cattgtctgt gcgatagaga gggatcatca aattatcatt ccaagcggtg
    22621 acatgactgt acaggataaa gatagaatct ttgtcactgg taaccgtgtc gatatgatac
    22681 tcttccataa ttattttaaa tcacgcgccg tgaagagcct tctcatcgtt ggagctggta
    22741 gaattgccta ttatctatta ggtatcctca aagatagtcg tatcgaaacc aaggttattg
    22801 aaatcaatcc tgaaatcgct agcttcttta gcgagaaatt cccaaatctc tacatcgttc
    22861 aaggagatgg aaccgcaaaa gatatcctgc tggaagaaag tgctcaacac tatgatgccg
    22921 ttgcgactct aacaggagtc gatgaggaaa atctgattac atctatgttc cttgacaggg
    22981 taggtgtaca gaaaaatatt actaaggtca atcgtaccag tctcctcgag attatcaatg
    23041 cgcctgattt ttcaagtatc atcacaccta aaagcatcgc tgtagatacg attatgcact
    23101 ttattcgtgg tcgagttaat gcccagtatt cagaccttca agccatgcac catctagcca
    23161 atggccaaat cgaaaccctg caattccata tcaaggaagc caataaaatg actgccaaac
    23221 ctctttctca actgaaattg aaaaaagggg ttcttattgc agccattatt cgaaagggca
    23281 agactatttt cccaactggg gaggatatgt tggaagttgg agacaagctc ctagtaacaa
    23341 ccttgttgcc aaacatcacc aagatttatg acttgattgc gaggtaagaa atgaataaaa
    23401 gtatgattcg ttacctcctt tcaaagttac ttttgattga agctgttctc ctcttggttc
    23461 ctgtggctat cgctgtctat taccgtgaat cgagccaagt ctttacagcc ctcttttcga
    23521 ccatagggat tctcgtattg ttaggcggtt cagggagttt acagaagcca aaaaatcaac
    23581 ggatttatgc caaggaggga gtcttgatcg ttgccctctg ttggatcctt tggtctttct
    23641 ttggtggtct cccctttgtc ttttctgggc aaatccctag cgttattgat gccttttttg
    23701 aaattagttc tgggtttaca actactggag caagtatttt gaacgacgtt tcggttctca
    23761 gccgttccct cctcttctgg cgaagtttta cccacttgat tggagggatg ggagtgcttg
    23821 tttttgcact tgctattatg gacaatgcca aaaatagcca cctagaggtg atgaaggctg
    23881 aggttccagg tcctgttttt ggcaaggttg tatccaaact aaaaaacact gcccagattc
    23941 tctatctcct ttatctagct ctcttctccc tctttgtcat catctattat ctagctggta
    24001 tgcctctcta cgatagtttt gtcattgcta tggggacagc gggaactgga ggctttaccg
    24061 tctataacga cggaattgcc cactatggca gctcactgat tacctatctg gtcagtatcg
    24121 gagttctggt ttttggggta aatttcaacc tctactacta cctcatgctc cgtcgcatca
    24181 aggccttctt tggtgacgaa gaacttcggg cttacttggt cattgtactg gtttctacag
    24241 gcttgattag cctcaacacc ctctacctct acccagggtt ttcaaagagc tttgaaatga
    24301 ccttcttcca ggtttccaac atcattacaa caactggttt tggatatgga gatattacca
    24361 actggcccct cttctcccag tttatcctcc ttttcctcat ggcaatcggt ggctctgctg
    24421 gatcaactgc aggtggactc aagattattc gaggcctcat cctttcaaaa attgccaaaa
    24481 accaaatttt gtcaatccta tcgccccacc gtgttttgac tctccatgtg aatcaaacgg
    24541 tgattgataa agatacccag cataagattc tcaagtactt tgtcatctat gctatgattt
    24601 tgctagcgct tatctttatt gtcagcctag atagcaatga ttttctggtc gtgaccagcg
    24661 ctgtctttag ctgtttcaat aatatcgggc ctattctagg aaccacttct agtttctcaa
    24721 tctttagtcc catctcaaaa attctcctct cctttgcaat gattgcaggg cgcttggaga
    24781 tttacccaat cctccttctc tttatgaaaa gaacttggtc taagagataa aatacaaaat
    24841 ccctcttttt acaattgtga aagagggatt tttatattaa aaagggggaa cgtttttaaa
    24901 tccaagcctg tctgtaagca aagttcttac tcaaataaaa gatggaaaaa cttactacac
    24961 agcttggtaa tgctccaata caaattgtaa ggctttactt ggattctttg ttaaatgaat
    25021 atattccatt cctctggtag caactatctg aatacctaat ctttctgcat ccaccttcat
    25081 ctctctataa taactccgaa cttgtggagc cagaataatt aaatcataaa cacccataat
    25141 atcataatga gctccgtacg ctcctgaatt cgcaatcact ctaacttctg ctaattgagc
    25201 gccctcgtta attgcattgg ctaattgcgc acttgttcca gaccctgcac aaagaaccag
    25261 tactttcaac tccttacttt ttatttcatc taactcacca ggcattattt cacttgtctc
    25321 ctcctctaaa ataatatcat ttgagcttgc aacatcttct ttcatcagta actgtctatc
    25381 atacgctcta cagaatggca aataaatcaa tatgtcgaca actaaaatca aagataaaaa
    25441 tacaaaggag atagattgaa aattcgttcc aattaacaat cccaagggac caggaaaggc
    25501 ccaaggtaac tggatataaa atccattcat tccaaagaaa tcaataaaga cctttcctag
    25561 aaatacattc actggtggag tcatcaaaaa aggtacaaaa agatagggat tcaaaataac
    25621 tggcatacca aatagaagag gttcattcac tgcaaataaa acaggagtaa ttgtagcttt
    25681 acctaccgat tttaattgtt tagaccgcat aaagaaaatc aaaataaatg gtacaacaaa
    25741 ggtagccccc gttcctccga tagcagcgat ataatttccg aaattaggcg ttaaagaatg
    25801 ataaggaaac tgcccatttg caagaagttg agcattctct tccatattgc tcagttgtaa
    25861 agctgtaaca gcaggtaaga caatagatgg tccatgaatt ccaacaaacc aaagcaaagc
    25921 gcacataaac caaatcaaca tcatagcagg atatgattct gcccccttaa aaataggagt
    25981 caatagttgt tgaaatactt gggcaaaagg aacatctaaa ctaaaccgag atacaatatc
    26041 taacaaacca ctaataagta aaacaaaaga aaaaggaaaa atatctctaa aagcttgtga
    26101 tatagcccca ggaacttcct taggtaaatg aatagtaatg tctcgcttaa tacagaatcg
    26161 gtaaacattt acagtaataa aggcactgac aaacgaagtt atcaatcctt gagatcctaa
    26221 atagtttgtc gacaaacttg tagatcccgt tttctcatca actacaagcg ttacagttaa
    26281 tacaagatag ccacatatgg ccgccaacat tgcagaagta tcatttatta cctttccagg
    26341 aggcattttt ctattaacat ttccagccaa tgactttgca actgtccctg aaacaataac
    26401 acccaaaact cccatggtta gcatatacac tttcctcatc caggcaatag ctggactcgg
    26461 taactctact ccgaaatttt taggaatcat aataataatc atcaaaaagc ttgaaaacat
    26521 aattaaaggc atagtagcaa tgaatccatc tttaatagcc atcatataat tattagtaga
    26581 aattttttca aatttccctt gttgcttttc aatggcagcg actaacttat ccataaaaac
    26641 tcctcctgta aaaaatttaa gctcatagtt aaaatatatt aaacatcagt caaatcgcta
    26701 accttaattc cgttttagcc cttttaccca aagagcactt ttcttaatat atctcttctg
    26761 tgtttcataa tcaacaaaga aaagaccata tcgcttattg tagccattcg cccaagaaaa
    26821 ttgatcttgc aaagaccata taaaatagcc ttgaatattg actcccctat ctcgagcctc
    26881 taaaactttg tgtaaatgtt gctcaatata acggattctt ttactgtcat caataatatc
    26941 attctcgccc tctggcttaa cctctttaag ggctgtacca ttttcagtta aataaatgac
    27001 cggatgttga ggatattctt ctttgatacg aagcaacata tcaaataacc cttgaggata
    27061 aatattccaa tcccaatctg ttgtcggaat accaggcttt tttacaaatt cacctagagc
    27121 atttaattta aaagaagact gtccttttat tcctgttgaa ttaaattctt gtctattttc
    27181 acctttgtat tcacgaataa attctgaacg ataataattc atcccaaaca tcgtattaag
    27241 aggtgcagct cttttcataa tttctaaatc accatcttca ataataaagc tagaattatt
    27301 agcttccaat atttgattca agtgaaaaag cgtgtcatca ctgtagtagc ccaaaaaagt
    27361 tccatctaat agaaatttat tattataaac atcataccgt ttagctgcca aaatattttc
    27421 tttttgccca tcaataggat agcctggctt taaagcatga atacaaccta cctttccctc
    27481 aatccctaat tgatgaaatt cgaggactgc aagagcatgc gccaacaaca tgttatgatt
    27541 tgcttgaatt gcttcagata attgaaaatg gtgattcgga ggaaactgac ctcctatgta
    27601 ttggcctgca gcaagagaca tcagttcatt gattgtaaac caatgcttga cttctgtaaa
    27661 ttcttggaaa caaaagcgag catatcgtat gaaacgatca atattctctc tattcaacca
    27721 atcccctgtt tctaacattt tctgaggcga atcaaaatga tgtaaagaaa caaacggaat
    27781 cacattatat tttaagcagg actgaaagac tctatggtaa taacgaacag ccaatatatt
    27841 cggctcccca tctatatcag gaaatatacg aacccaagaa atagataaac gcaaagcctg
    27901 caaaccatgt tctgccgcca aagctatatc ctcttcgtaa cgataataaa aatcactagc
    27961 tggatctggt aagaacggac tattttcttg caaataaaca tcccacatat ttattccttt
    28021 gccatctacc ctagttgcac cctctacttg ataagcagcg gtagcagctc ctaataaaaa
    28081 ctccttcggt aaggctttaa cctgtaaatt ttccatgact aatcctcatt gcaaaccaat
    28141 atgttcttca atctttcgaa ttcgttcata ttcatcaata aaaaacttta cctgatcata
    28201 caatagcatc gttgtcatca aagtatcttg accatgaatc atgataaaac tcacttcaaa
    28261 attatctcca tatgcctcct ccgctaataa attagtctgt tctcgatggg cagacactat
    28321 tgagtcgttt gcagactcaa ccaattctct tgcctgttca aaatatccat ctctcgcaaa
    28381 cgccaaagca tccatcaaat ctgaccttgc atctcctgcg taagcgacaa ttgtaaaacc
    28441 aagcatattt atttcttctt ttgatttcat ctttcttcct cctcaatctt gaaccatctt
    28501 ttacacatca ttattaaaat gacttcgcta cgatacaaat agaaagtcga ccctaaatat
    28561 cttaaaaatc cttaaatttc ataatattta ggatcaatct tctctgaata ccttggttca
    28621 ttttctagac ttatgattta taagtggaaa ccagcgtaat tttttgctac ttcaattaca
    28681 cgataaacat ccaaattaga ttggaatagc agttcgtgcc cacggatata attcaacaca
    28741 tttttccact catcttgagc ttgccttgtt tttccggttg cttgaagata taaagccttc
    28801 gccatcttga caacatattc acgatgataa ctgagctgtt tccattcatc cttttgacta
    28861 tttaataact tagaaatatt ttcctcaata attggtaaaa aattatcagc tagattgtaa
    28921 gctatataat aatgattcgc taaaacatca ctttgacggc tgccaattgc attaaaataa
    28981 tcacaagagg aataaatgga taatttttct aaatattcaa caacagactg ccaattttcc
    29041 ccatacaaag cagaaaagta ttcttcaatc aattcttcat aatttcttgt cttcttccag
    29101 agcatttgcc ccatgacata attaggaaaa ttatgaggga atccggcacg taattcttga
    29161 cacgaaatgt acccgttcaa atgtaggttg gaaagataag atacatctct gtaaatagtt
    29221 tgactaattt tcatatagcc taaatcgcca taatgagcac gccctaaagg atagtcatat
    29281 acgaaactat ctcctttaaa tgctttttgc cactcaaaaa gataagataa attttcctca
    29341 agagaattcg gaagtataat tttattacgc agataaggtt taggcgtagg tatggaattg
    29401 tcaaaatcta catctgcata actcatttca aatgttcttg taatcggtgc aaacatcatg
    29461 gtaaagcgtt caggattatc taatttttct ttctgaggtg cccataacaa ctcatgataa
    29521 agcagaaaac aaatctttgt atctaatccc tcactcgtta aagccctatc caattgattg
    29581 agaatacgaa tatactgatc cgaaaccaat tcttgtctac agttttcgca ttcacaaata
    29641 ttattacgag catccgacaa ccatacatgt aagtagttaa catcaggtct tttcttggca
    29701 taatccttga taatttctac catcttatca gctacatctg gatttgaaaa atccaggctg
    29761 gttaaaatcg gagccgtatt aaacaattct cgtttcccgt ttatttcagc gacatagggt
    29821 ttcttctcct ctgaaatact aagacctgat tcccagccaa attttgaaga gtaacctaaa
    29881 acttcacctg tccatccatg accaacacga tgatgaataa gacctctttt ttgcaattct
    29941 ttatccaacc tatcactcaa ttcttgtact aattcatttg aaaattgttc tttatttaga
    30001 tatggattaa attcatgttc ataccaacgt ttcaaaaaag agtagggatt ttcaaactgg
    30061 atgaaaaaac tgttcatccc aatcttaggt agccaatcaa tgaaatctag tatattttca
    30121 aatgaatccg ctccctctat acatactccc ctatgatagt aactggctgt ttcatctata
    30181 gatagctgtt tatctaaaaa atcttcaaat cgtaactctg gaacaaagtc atgtccgcgc
    30241 cctggtctag tatacacaac cccaaattca tgaaacattc ggtaaattcc aataagtaaa
    30301 cctacaattg tattagactc aattctcccc ttacccttgt ctaatgagat aagaacatgg
    30361 tctcttctat cctctttatt gactaatcct acaaaaatat ccgcttcctt ctcctcgaca
    30421 agttctatgt cagtcttaaa gacccgattt atatagtaac ttaattcctc taaggcaaag
    30481 ctagaataag tatttttctg cttatcaaat actctgataa ccatcttatt tccctccaac
    30541 agtagctttt tctttttcaa gattgcgttt atctgcaatt ttgaagaatg gataataaat
    30601 tgctacagaa accaaaatca aaacaacttg taatagagct cctcgccaac tagctcctgt
    30661 cgcaaggaag cctcctatga tcggtggcat tgtccacgga aggattacac ctgttgtata
    30721 gggtactaat cctacagcca ttgatacata ggtaattaag gcattgattg taggagtagc
    30781 aataaacgga atcagcataa tcggatttaa aactgttgga aacgtaaata gaatagctgt
    30841 attgatatta aaaatagacg gtataatagc tagcttacct aatgttttat tcgcacgact
    30901 cttactaaat aggaagagac aaatcgcaag accaatagtc gctccaccgc caccaataaa
    30961 tacaaataaa tctttaaacg gtaatgtaat aatgtgttgg agtgtttgtc ctgcagccac
    31021 agcttcttgg ttttctgtag taaattgtaa ccaaactggg tctacaaaag catttaaaac
    31081 ttgtccccca ttaactccac agaaccaaaa gaatgagttt acaataacac atagaatcat
    31141 acctggaagc gttcctgcaa ttaacttaag cggtgttcca acaattgcac ctaggagtcc
    31201 gttgagacct cctgcaactc ctgccgcttc aagacctttt aagaccagag cccacaaaac
    31261 aaaagtagta aagccaggta aaagagctga aaatgattta cttaccacat ctgggacacc
    31321 acttggcatt tttatcgtaa ttccgcgctg gataaacata cgataaatct ctgctgtaac
    31381 caatccaata gtaatcgcca taaacaaaga agatgcattc agactagaaa atggtattgc
    31441 gccgccaaat aactgcttga cctgctcccc atttttatca taaaccatac tcgaaaaacg
    31501 aggtgccatc aatacaaaac tggataaggc tatgatccct gccgacggac catctgtacc
    31561 atatccttcc gacaacctgt aggcaatacc gaaacaagcg accaaggaga taatcgctac
    31621 tgttgactga ttcatagttg tcaagatact tagcaatcca acactattca gccaatttgt
    31681 aaaagcctct tgaggccaac tgattagaat aagaaataaa gagccgacta aaatcaaagg
    31741 cattgccatc ataaatcctt cacgaatagc tttcaaatgc cgttggttgc caactttttc
    31801 accaaacgga gcgacttttg tttctaaaaa cgctaaaata ttgttcatca ccggaactcc
    31861 tttttttatt ttttataaat taaatatacc actaacagaa agcgttgtca atatattttt
    31921 tgttattttt acaatatttt tttctttgta tagaataata attttaattg attttttctt
    31981 atgtttaata taaaataaac caaaggagga aacaaatgat tacaaaacaa tcagcctttt
    32041 tacaaaatag agccactata ctggagtttc tatatcgaaa tccagcaaca tcccgtacag
    32101 atattgttaa tgaaacagga cttactccag caacaacgac taacatcata aaagagctaa
    32161 gcgaacagtc cctcatatac gaaactggtg atgaatttag cgagttttcc ggatctggaa
    32221 gacgtagaaa aactatttct atcacagata atattccgta tgttgttgga ggtattgaaa
    32281 taaacgtcct aggtatcttt ctcagtctat gtgacttaca agggaaaact cttttcgaga
    32341 cagaaatttt gaatgaagat tatcctattt cagaaatcaa ttccaccatt accaatatga
    32401 taaaaacagc tatagagtac gtccctttgg aaacaaaatt acttggattt ggcttatcaa
    32461 tacctggaca ttataacaaa gactccggaa gtatcattac aaacaacccc atatgggaat
    32521 cttttaattt attaaatgta attaaaagat tcaattttcc ttttattgta aaaaataata
    32581 tcgattgtat ggctatagga caataccttt ttaatccaca caataccccc gataacttta
    32641 ttttcctgca cgctggatta ggtatttaca cttccttttt cacaaaagaa aaaataggag
    32701 cctctaaaaa tccttatatc ggagaaattg gacacaccat tgtcgaattg aatgggcaat
    32761 attgtgaatg cggaaaaaaa ggttgtttac aaacatatat ttcggatgct tggttaatca
    32821 aacacgccca attattattt aaaaattccc aactaactgt actaaaaagc cttgtaaaga
    32881 ctgaaaaaga cattcattta gacacccttt taacggctta taatttaggc gactccgctt
    32941 tacgtcaaca aattgataaa ggagtcaatt tattagccac ttctattgca aatctcctcc
    33001 tcatcaatcc tgctgataaa atctatatca acagtcaatt gcttaattat caacctttca
    33061 ctcatgaagt cagggataaa atccaagacc agctccactt cgttcccttt actcgtaata
    33121 tagaaattga aattttacct tacaacaaac atcgtggaag tataggagct tgtgcattag
    33181 ctatcgtcgc ttttttcata gaacatagca atgtattaca agatattatt tcaccttaat
    33241 atattagaaa tctatagacc tgtttaaatc aactataacc tgtagtagat atctcgtatt
    33301 tagacaatat gaaaacaaga cgacttccat ataggaaacc gccttctctc tatgttgagt
    33361 gatttatatt aaaataactt ttcttctagc tgcattttat tattataaaa acattcatca
    33421 taaccctgaa cttaaataac gatttttatt caagatacat actcctagaa taaactttat
    33481 atgaaattct catttttgtt tttacaattc tccttagtta aatcttgttt aatatatgtt
    33541 ttacatatag tatttagcgc cacatagtac tgaactctct ccaaaaacgg ttattcctct
    33601 ttgaataggg cgttatcaca agaaaagcat ctccacgttt caacttcata tggctcaaaa
    33661 acaatcaatt gatgctaaaa cctgtaccta gatgtttcgg ttcataaaac catgaaactg
    33721 taaaagtgga tgaaattgat agcgatagtc aaatcaagag gcatcataac tctaaaaagt
    33781 cacaatatat aagttcatcc tcggaaaaat atcattctaa ttgttgaaat gcctacatga
    33841 aaagaaacgt caaatactca tgaaacaacg aatacaggta tcaaaactat gacaaaacaa
    33901 gtccctaaat ttactaaaga cactgctcaa ctttacacct gtaaatggtt gttgtataat
    33961 aaagttacaa agatgtacga ccacactgtt gtaaatcata gtgttcgcga atatattact
    34021 gatagcattt ctacaaatac aattgaagag actggataga ctttaaacga aatatgtcag
    34081 tgttttggca ttcctagcct tcatatcatt taaagaattc tatagacaaa atttttccca
    34141 atacagacac tcgtaacaac tgcttcattt ttctaccaac atatttagga acaggataag
    34201 atacaagagg attaatccat agatcagttc tataccaatc taagacaaat aagctaaaaa
    34261 aacgattgat aataagcaaa tagattccaa attttctcta tctgctcatt ttaataaaca
    34321 atactagtgt aactatcctt ccagtcagaa gcttgtcaaa tcacaccgaa aattcttcta
    34381 aaatttatct cgttaggcaa tcaagcaaaa actcgacgat agtacaaaca ttatcataca
    34441 gaattgactt cctaaattat atactttagt aaggttttcg tataagaaaa aagattcatt
    34501 ttacatttct aaacattctt ttctaagatg aaaaacagaa tttttcgatt gtgatttaaa
    34561 gcaacaagaa gattttcagt atcatcctat agatacgagc taattaagaa aaactacatt
    34621 ttcgaatata aactacaata atataaacta aattttatag gaggaagaca atggattggt
    34681 acgattatat gatacaggca tccaaacaat cacaattcaa cgcaagccat tggtttcgct
    34741 atttgcgaaa agttattttt gaagactatt cttatttaac aaaccaagat gtagaaaagt
    34801 tgctagactc caaagaacta acccgttttc aaaaaattag cttgaagtat gcctttcaag
    34861 agcatactcc aactcataaa tatgtgattt cattaaataa acctgctaag ttaaccaatg
    34921 ttcaaaaatt gatggagaaa tacaaacatg gataaaatga aaccggtctt ccaagcccta
    34981 aataaggaat taattcagga aaatctgact ttaacaatta tctgtgtcga tggttatgtc
    35041 ttagaatatc atggtttaca tgccacacaa gatgttgatg ctttttatga ccaaaatcag
    35101 aaaatcaatg aaattattgc tcgtgtagga aaacagttta atcttaacat ccacgaagag
    35161 ttatggctca acaatcatgt tgcaaagcaa atatgaacaa acaacctccc ttaagtttat
    35221 gcgaatcctt gtactcattt gagaatctga ccgttttagt agtccctatt gagtatgtgt
    35281 taggaatgaa gatgatgagt atcagagagc aggatttgca agatattggt gcaattatta
    35341 aatacaaaaa ctttcattca ccattcgata cctttaaata tttaaaagac atgggatttg
    35401 atactattga cctctctgtt ctattagaaa gttttagtta tgcttatggt atggattggt
    35461 tagaaaaatt ttttaaagaa aatcaagata aacttcgcga attttattaa cagtatcaaa
    35521 caagatgatt gtcaattagc cagtcgtctt gttttttatg atgaaatgaa ataaaatctg
    35581 aacaaatcgc ttagagaatt ccagtcaatt tctagcgctg tttgagacgt ttcagtggac
    35641 tatagtaaaa tgaaataaga ataggacaaa tcgatcagga cagtcaaatc gatttctaag
    35701 aatgttttag aaataaaggt gtactattct agtttcaatc tattatattt cagattcggt
    35761 ccactattcc ttcccaaaaa cattgcatat tgcgccgaag gaattgctca tactatccca
    35821 agcacaaaac cctcagtcgt ttgaccgagg gttccttttt attattcaag aacttgatta
    35881 gctcaatgca tccaaggcgt catccattga aagaacttcg tggaagacac gttgtgtcaa
    35941 ttcagttttt tgttctggag tgaggtattt agtgtttaca cagtatccag agatacgtac
    36001 gataacgtct tcgcctgaca tgattttttc gtaaacatcg ttcaagtcca taacgttcaa
    36061 gttaacgtgt tgtccaccgt tttcgaagta accatcaagg attgttacca agttatcaac
    36121 ttgttcatca cgagtcttac caagagcgcg aggtgatact tgtgtagtca atgagatacc
    36181 gtcagctgca taactaaagt caaggctaga aagtgagttc aagttttgca accaaccacc
    36241 tttagctttg ttagatgggt tagcacctgg tgagaagaat tcaagtttag acaagttcac
    36301 agaaccatct tcgttgaggt atacaccttt gtgaactggt gagttaccag tttgtttaga
    36361 gtaagcaacg ttagatgtga ttgtcaaaag tgatactgta gcttctgcgt ctttgtatag
    36421 tttgtggcta cgtagacgag ttgtgtaagc ttcgatcaac cattctgcca attcgtttga
    36481 acgtgggtca tcttcacccc agcgtgggta gtcaccgatt gtttcgtaat cgtagatgta
    36541 gccatcttcg tcacggattg gtttaactgt agcgtatttg atagctgaca atgtatcaac
    36601 agtgttagca aatccacaga taccgaatcc catgttggca cgttgtttag ttggcaagaa
    36661 ggccatttga acagcttcgt agttgtacct atcagtcatg tagtggatga tgttcaaggc
    36721 atctacgtaa gtgtcagtca accagtcaag agatttttca aagttcgctt taactgattc
    36781 gaattcaaga acttcgtcac ggattggttc gatatcaaat actttgtagt ctttgtgaac
    36841 atcgtcgtaa ccaccattca aaccagtaag aagggcttta agaacgttta cacgagcacc
    36901 gaagtactgg atgttgtggc gttgttcttc attttctgga tcaagtggag acacacagca
    36961 tgagatacag ctcatttcac catatccgtc tttagccatt gttgttacac cttcgtattg
    37021 gatagaagag tgtttgtggc tcatgtgcat acagtagcga cggaagttgt atggcaattt
    37081 gtcagtccaa agaactgtca agtttggttc tggtgagtta ccgatgttgt caagagtgtt
    37141 caagaaacgg tagtccatct tagtaacacg gtgacgaccg tcgttaccca taccagccat
    37201 agaagttgtg ataaaggttg ggtcacctga gtacaattgg tcataagctt tggtacgagc
    37261 aaatttaact gtacgaagtt tcataacgaa atcatcaacg aattcttgga tttctgattc
    37321 agtaaatgta ccacgagcaa ggtcacgttc tgcaaagatg tccaatacga ttggtacacg
    37381 acctagagat gtagcagcac cgttaatcac acggcagaca gccatgaaag caatgttaac
    37441 ccattggatt gcttctttca cgttcatcgc tggtttgcga acatcaaccc cgtaaaggtc
    37501 acccaggcga acaacttgtt gcaatgcttg gtattgaagg tttacttctt cacgaagacg
    37561 gattgtttct tcatcgattt ctttgattgc attccagtca tttacttttt cttgcatcaa
    37621 gtagtctgca ccgtaaagag caagacgtgc gtaaacaccg atgatacgtc cgcgtgagta
    37681 tgcatctgga agaccagtta cagtgtgtgc gtgacgagcg cgacgaatat ttgaagtgta
    37741 ggcacggaaa ataccgtcgt taactgttgt tacatattta gtgaagattt cgtgaacagc
    37801 tgggtctggt tcgtatccat tttctttcaa agtagtttca gccatacgga taccaccttt
    37861 tggcatgaag ttcaatttga agagttcatc gttttggata ccgaagataa cttcattttc
    37921 tttgtcgata aatccagcag ggatatcagc gatagatgtt ggacgagtgt ccattgggaa
    37981 acgagtttct tcgtagtgtg ctttagtttc ttctacaatt ttcttgatgt gaagtgaacg
    38041 ctctgttggt cctgcaagga agctttcgtc tccatcataa ggtgtgtagt tagcttgtac
    38101 aaatcgtgat acacttgctt tttctttcca atctacgcct ttgaagcctt cccaagcttt
    38161 gtcaaaaata tcttgtgctt caacaactgt cttaacaacc atattaatgt cctctttttt
    38221 ctagtaacag tcatctgtta cattcataag acaagtatac catatagtaa ccgatttcaa
    38281 caagtgaaaa ttccctattt ttacactttc ttttctaaaa cagtctatat tttatttcaa
    38341 actgtattat atttttgaaa aaataaagtc cttttttctt tttttcagaa aaaagggtat
    38401 aataaaagaa aataagcagt aacactcaat ggaaatcgaa
//
LOCUS       DBERAE010000015        35014 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.15, whole genome shotgun sequence.
ACCESSION   DBERAE010000015 DBERAE010000000
VERSION     DBERAE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.15"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..210
                     /locus_tag="ACL70N_000941"
     CDS             <1..210
                     /locus_tag="ACL70N_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS0589761.1"
                     /translation="WKVRNIEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAV
                     LDNTVIARDRITVPIDPLCGKDFIE"
     gene            455..1789
                     /gene="trmFO"
                     /locus_tag="ACL70N_000942"
     CDS             455..1789
                     /gene="trmFO"
                     /locus_tag="ACL70N_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGS0589762.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1873..2610
                     /gene="pyrH"
                     /locus_tag="ACL70N_000943"
     CDS             1873..2610
                     /gene="pyrH"
                     /locus_tag="ACL70N_000943"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGS0589763.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2619..3176
                     /gene="frr"
                     /locus_tag="ACL70N_000944"
     CDS             2619..3176
                     /gene="frr"
                     /locus_tag="ACL70N_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGS0589764.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3236..4090
                     /gene="cvfB"
                     /locus_tag="ACL70N_000945"
     CDS             3236..4090
                     /gene="cvfB"
                     /locus_tag="ACL70N_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGS0589765.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4099..4314
                     /locus_tag="ACL70N_000946"
     CDS             4099..4314
                     /locus_tag="ACL70N_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGS0589766.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            4400..5368
                     /locus_tag="ACL70N_000947"
     CDS             4400..5368
                     /locus_tag="ACL70N_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGS0589767.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5561..6061
                     /locus_tag="ACL70N_000948"
     CDS             5561..6061
                     /locus_tag="ACL70N_000948"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589768.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGFFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            6064..6389
                     /locus_tag="ACL70N_000949"
                     /pseudo
     CDS             6064..6389
                     /locus_tag="ACL70N_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6690..7801)
                     /gene="ald"
                     /locus_tag="ACL70N_000950"
                     /pseudo
     CDS             complement(6690..7801)
                     /gene="ald"
                     /locus_tag="ACL70N_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            7978..8547
                     /locus_tag="ACL70N_000951"
     CDS             7978..8547
                     /locus_tag="ACL70N_000951"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0589769.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLVNPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8615..9265
                     /locus_tag="ACL70N_000952"
     CDS             8615..9265
                     /locus_tag="ACL70N_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS0589770.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9249..11489
                     /locus_tag="ACL70N_000953"
     CDS             9249..11489
                     /locus_tag="ACL70N_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGS0589771.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKAAQHGSKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            11631..11855
                     /locus_tag="ACL70N_000954"
     CDS             11631..11855
                     /locus_tag="ACL70N_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589772.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYYSYSEYPVGSGWNYARYEVINYYTGGY"
     gene            11887..12474
                     /locus_tag="ACL70N_000955"
     CDS             11887..12474
                     /locus_tag="ACL70N_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589773.1"
                     /translation="MLRLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            12478..13659
                     /locus_tag="ACL70N_000956"
     CDS             12478..13659
                     /locus_tag="ACL70N_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589774.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDISSEEYQFAKNNLDVQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQAMYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    13819..13950
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            13966..14496
                     /gene="infC"
                     /locus_tag="ACL70N_000957"
     CDS             13966..14496
                     /gene="infC"
                     /locus_tag="ACL70N_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGS0589775.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14529..14729
                     /gene="rpmI"
                     /locus_tag="ACL70N_000958"
     CDS             14529..14729
                     /gene="rpmI"
                     /locus_tag="ACL70N_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGS0589776.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14781..15140
                     /gene="rplT"
                     /locus_tag="ACL70N_000959"
     CDS             14781..15140
                     /gene="rplT"
                     /locus_tag="ACL70N_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGS0589777.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15198..15578
                     /locus_tag="ACL70N_000960"
     CDS             15198..15578
                     /locus_tag="ACL70N_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0589778.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15828..16628
                     /locus_tag="ACL70N_000961"
     CDS             15828..16628
                     /locus_tag="ACL70N_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGS0589779.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16591..17577
                     /locus_tag="ACL70N_000962"
     CDS             16591..17577
                     /locus_tag="ACL70N_000962"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGS0589780.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGAAAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17677..19785
                     /gene="lytB"
                     /locus_tag="ACL70N_000963"
     CDS             17677..19785
                     /gene="lytB"
                     /locus_tag="ACL70N_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS0589781.1"
                     /translation="MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANE
                     WVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQD
                     GKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYF
                     KSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHY
                     YYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEW
                     IWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDG
                     KIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQ
                     AWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKL
                     SYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRF
                     YHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEEL
                     DKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFF
                     GITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPY
                     WGEKIASVMMKINEKLGGKD"
     gene            complement(19846..21501)
                     /gene="pavA"
                     /locus_tag="ACL70N_000964"
     CDS             complement(19846..21501)
                     /gene="pavA"
                     /locus_tag="ACL70N_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGS0589782.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21606..22103
                     /gene="ybeY"
                     /locus_tag="ACL70N_000965"
     CDS             21606..22103
                     /gene="ybeY"
                     /locus_tag="ACL70N_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGS0589783.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22084..22479
                     /locus_tag="ACL70N_000966"
     CDS             22084..22479
                     /locus_tag="ACL70N_000966"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS0589784.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22496..23395
                     /gene="era"
                     /locus_tag="ACL70N_000967"
     CDS             22496..23395
                     /gene="era"
                     /locus_tag="ACL70N_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGS0589785.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKIPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23444..24268
                     /gene="mutM"
                     /locus_tag="ACL70N_000968"
     CDS             23444..24268
                     /gene="mutM"
                     /locus_tag="ACL70N_000968"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGS0589786.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24268..24873
                     /gene="coaE"
                     /locus_tag="ACL70N_000969"
     CDS             24268..24873
                     /gene="coaE"
                     /locus_tag="ACL70N_000969"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGS0589787.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24860..26059
                     /locus_tag="ACL70N_000970"
     CDS             24860..26059
                     /locus_tag="ACL70N_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGS0589788.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26059..26208
                     /gene="rpmG"
                     /locus_tag="ACL70N_000971"
     CDS             26059..26208
                     /gene="rpmG"
                     /locus_tag="ACL70N_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0589789.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26248..26481
                     /gene="secG"
                     /locus_tag="ACL70N_000972"
     CDS             26248..26481
                     /gene="secG"
                     /locus_tag="ACL70N_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGS0589790.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26583..28937
                     /gene="rnr"
                     /locus_tag="ACL70N_000973"
     CDS             26583..28937
                     /gene="rnr"
                     /locus_tag="ACL70N_000973"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGS0589791.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYLEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRDSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28900..29367
                     /gene="smpB"
                     /locus_tag="ACL70N_000974"
     CDS             28900..29367
                     /gene="smpB"
                     /locus_tag="ACL70N_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGS0589792.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29383..30243
                     /gene="tehB"
                     /locus_tag="ACL70N_000975"
     CDS             29383..30243
                     /gene="tehB"
                     /locus_tag="ACL70N_000975"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGS0589793.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30316..31269
                     /gene="coiA"
                     /locus_tag="ACL70N_000976"
     CDS             30316..31269
                     /gene="coiA"
                     /locus_tag="ACL70N_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGS0589794.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIQQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31288..33090
                     /gene="pepF"
                     /locus_tag="ACL70N_000977"
     CDS             31288..33090
                     /gene="pepF"
                     /locus_tag="ACL70N_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS0589795.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33092..33805
                     /locus_tag="ACL70N_000978"
     CDS             33092..33805
                     /locus_tag="ACL70N_000978"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGS0589796.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEEFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33872..34813
                     /gene="prsA"
                     /locus_tag="ACL70N_000979"
     CDS             33872..34813
                     /gene="prsA"
                     /locus_tag="ACL70N_000979"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGS0589797.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34930..>35014)
                     /locus_tag="ACL70N_000980"
     CDS             complement(34930..>35014)
                     /locus_tag="ACL70N_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0589798.1"
                     /translation="IDYYNNKRIKVKLKGLSPVQYRTKSFR"
BASE COUNT        10538 a         6511 c         7920 g        10045 t
ORIGIN      
        1 tggaaagtaa gaaatattga agctgaggct attagaagaa attgtgagcg tggtgctatt
       61 ttttcaggta aaataaaata tcacgaagat tcacagttta aaggagatca ctatgttgaa
      121 tgttatgctg ttttagataa tacggttata gcaagagata gaataacagt ccctatcgat
      181 ccgttatgtg gaaaagattt tatagagtag catataattg attcttaact ggaatactca
      241 ctatctcttt acatcaagaa aatgactaaa cagggaagtt tgccttcttc cctttttttg
      301 ttatactagt agaagaaaaa atagaaagat ttgtgggagt gaaaaagtcc tgtggacttt
      361 ttcagcctga gccaagaaac tcgaaagctt gtaagtctga ttggcttttt caatgtgaat
      421 cttaacttca cactcccaaa gaggtattag tgtcgtgtct caatcttata tcaatgttat
      481 cggtgctggt ttggcaggtt ctgaagcagc ttaccaaatc gcagagcgtg gtattccagt
      541 taaactatat gaaatgcgtg gtgtcaagtc tacaccccag cataaaacag acaattttgc
      601 tgagttggtt tgttccaatt ctttgcgtgg ggatgctttg acaaatgcag ttggtcttct
      661 caaggaagaa atgcgtcgct tgggttctgt tatcttggaa tctgctgagg ctacacgtgt
      721 tcctgccggt ggagcccttg cggtggatcg tgatggtttc tctcaaatgg tgaccgaaaa
      781 agtggtcaac caccccttga ttgaagtggt gcgtgatgaa attacagaat tgccaacaga
      841 tgttattaca gttgtggcga ctggtccctt gactagcgat gccctggctg aaaagattca
      901 tgcccttaat aatggcgatg gcttctattt ctacgatgca gcagcgccta ttatcgatgt
      961 caacactatc gatatgagta aggtctatct caaatctcgt tatgataagg gagaagcagc
     1021 ctatctcaat gctccaatga ccaagcaaga gtttatggat ttccatgaag ccttggtcaa
     1081 tgcggaagaa gcaccgctca attcttttga aaaagaaaag tactttgaag gatgtatgcc
     1141 aatcgaagtt atggccaaac gtggcattaa aactatgctt tatggcccta tgaagccagt
     1201 cggtcttgag tatccggacg actacacagg acctcgtgat ggagaattta aaacacctta
     1261 tgcggttgtg caacttcgtc aggataatgc agctggtagc ctatacaata ttgttggttt
     1321 ccagacccac ctcaaatggg gagaacaaaa gcgtgtcttc caaatgattc cgggtcttga
     1381 aaatgcggag tttgtccgtt atggtgtcat gcatcgcaat tcttacatgg attcaccaaa
     1441 tcttcttgag cagacttacc gttccaagaa acaaccaaat ctcttctttg ctggtcagat
     1501 gacgggggtg gaaggctatg ttgagtcggc ggcttcgggc ttagttgcgg gaattaacgc
     1561 agctcgtctc ttcaaggaag aaagcgaggt tattttcccc gagacgacag cgattggaag
     1621 cttagctcat tacattaccc atgccgacag caaacatttc caaccaatga atgtcaattt
     1681 tgggatcatc aaggagttgg aaggcgagcg tatccgtgat aagaaggctc gttatgaaaa
     1741 aattgcagag cgtgcccttg ccgacttaga ggaatttttg actgtctaat ttttttgaaa
     1801 gaattgttca tgatactata aaaatcttag aaattgtgat aaaataggta ggatgaaaga
     1861 aggagagtga aaatggcgaa tcccaagtat aaacgtattt taatcaagtt atcaggtgaa
     1921 gcccttgccg gtgaacgtgg cgtagggatt gatatccaaa cagttcaaac aatcgcaaaa
     1981 gagattcaag aagttcatag cttaggtatc gaaattgccc ttgttattgg tggaggaaat
     2041 ctctggcgtg gagaacctgc agcagaagca ggtatggacc gtgttcaggc agattacact
     2101 ggaatgcttg ggactgttat gaatgctctt gtgatggcag attcattgca acaagttggg
     2161 gttgatacgc gtgtacaaac agctattgct atgcaacaag tggcagagcc ttatgtccgt
     2221 ggacgtgccc ttcgtcacct tgaaaaaggc cgtatcgtta tctttggtgc tggaattggt
     2281 tcaccatact tctcgacaga tacaacagcg gcccttcgtg cagctgaaat cgaagcagat
     2341 gccatcctca tggctaaaaa tggcgtcgat ggtgtgtaca atgccgatcc taagaaggac
     2401 aagacagccg ttaagtttga agaattgacc caccgtgatg ttatcaacaa aggtcttcgt
     2461 atcatggact caacagcctc aaccctctca atggacaacg acattgactt ggttgtcttc
     2521 aacatgaacc aatcaggcaa catcaaacgt gtcgtatttg gtgaaaatat cggaacaaca
     2581 gtttcaaata atatcgaaga aaaggaataa gaaagaatat ggctaacgta attattgaaa
     2641 aagctaaaga gagaatgacc cagtctcacc aatcacttgc tcgtgaattt ggtggtatcc
     2701 gtgctggtcg tgccaatgca agcttgcttg accgtgtaca tgtagaatac tatggagtcg
     2761 aaactcctct taaccaaatc gcttcaatta cgattccaga agcgcgtgtt ttgttggtaa
     2821 caccatttga caagtcttca ttgaaagaca tcgaacgtgc cttgaacgct tctgatcttg
     2881 gtatcacacc ggctaatgac ggttctgtga ttcgcttggt tatcccagct cttacagaag
     2941 aaactcgtcg tgaccttgct aaagaagtga agaaggtcgg cgaaaatgct aaagtggctg
     3001 tccgcaatat ccgtcgcgat gctatggacg aagctaagaa acaagaaaaa gcaaaagaaa
     3061 tcactgaaga cgaattgaag actcttgaaa aagacattca aaaagtaaca gacgatgctg
     3121 ttaaacacat cgacgacatg actgctaaca aagagaaaga acttttggaa gtctaaaaat
     3181 aaacagaaaa actcagttgg cattgctggc tgagttttat tcgaaagaag gaaatatgaa
     3241 tacaaatctt gcaagtttta tcgttggact gatcatcgat gaaaacgacc gtttttactt
     3301 tgtgcaaaag gatggtcaaa cctatgctct tgctaaggaa gaaggccaac atacagtagg
     3361 ggatacggtc aagggttttg catacacgga tatgaagcaa aaactccgcc tgacaacctt
     3421 agaagtgact gccactcagg accaatttgg ttggggacgt gtcacagagg ttcgtaagga
     3481 cttgggtgtc tttgtggata caggccttcc tgacaaggaa atcgttgtgt cactcgatat
     3541 tctccctgag ctcaaggaac tctggcctaa gaagggcgac caactctaca tccgtcttga
     3601 agtggataag aaagaccgta tctggggcct cttggcttat caagaagact tccaacgtct
     3661 tgctcgtcct gcctacaaca acatgcagaa ccaaaactgg ccagccattg tttaccgtct
     3721 caagctgtca ggaacttttg tttacctacc agaaaataat atgcttggtt ttattcatcc
     3781 tagcgagcgt tacgcagagc cacgtttggg gcaagtatta gatgcgcgcg ttattggttt
     3841 ccgtgaagtg gaccgcactc tgaacctctc cctcaaacca cgctcctttg aaatgttgga
     3901 aaacgatgct cagatgattt tgacttattt ggaaagtaat ggcggtttca tgaccttaaa
     3961 tgataagtca tctccagacg acatcaaggc aacctttggc atttctaaag gtcagttcaa
     4021 gaaagcctta ggtggtctta tgaaggctgg taaaatcaag caggaccagt ttgggacaga
     4081 gttgatttag ggaggcttat gagaaaatca ttttacactt ggctcatgac cgagcgcaat
     4141 cctaaaagta acagtcccaa agcaattttg gcagacctcg cttttgaaga ggcagctttt
     4201 ccaaaacaca cagatgattt tgatgaggtc agtcgctttt tggaggagca tgccagtttc
     4261 tcttttaacc taggagactt tgacgctatc tggcaagaat acttagaaca ctagcattta
     4321 ttcactaggt ttgggctagt aatttctcca tccctctgct ataataaaaa gaaataaaag
     4381 gattagagag gttctttatt tgaaggaaca ttcaatagac attcaactga gtcatccaga
     4441 tgacctgttt catctttttg gttccaatga acgccatctt cgtttgatgg aagaagagct
     4501 tgatgttgtg attcatgctc gtacggagat tgtccaggtt ttgggagaag agtctgcttg
     4561 cgaggaagcc cgtcaggtta ttcaagctct catggtcttg gtaaatcgtg ggatgaccgt
     4621 tggtacgcca gatgtagtga cggctattag tatggtcaaa aatgatgaaa ttgacaagtt
     4681 tgtcgccctt tacgaagaag aaatcatcaa ggataatact gggaagccta tccgcgtcaa
     4741 aaccttaggt caaaaacttt atgtggacag tgtcaaacag catgatgtga cctttggaat
     4801 tgggccagca ggtacaggga agaccttcct tgcagtgacc ttggcagtga ctgcccttaa
     4861 acgtgggcaa gtcaagcgaa ttatcctaac tcgtccagcg gtggaagcgg gagagagtct
     4921 tggatttctt ccgggtgatc ttaaggagaa ggtggatcct taccttcgtc ctgtttacga
     4981 tgccttgtat caaattcttg ggaaagacca aacgactcgt ctcatggagc gtgaaattat
     5041 cgaaattgcg ccccttgcct atatgcgtgg ccggaccttg gatgatgcct ttgtcattct
     5101 cgatgaggcg caaaacacga ccatcatgca gatgaagatg ttcttgacgc gtttaggctt
     5161 tcattctaag atgattgtca atggagatat cagtcagatt gacctgccac gtaatgtcaa
     5221 gtccggtttg attgatgctc aagagaaact caagaacatc catcagattg actttgttca
     5281 tttttcagcc aaggatgtgg ttcgccatcc agttgtcgct cagattatcc gagcctatga
     5341 atattctact gaagttgcac acgactgatt ttgaggaagt tcgcctgcaa aagaatatac
     5401 ttttgagaga ggaaaatcca gttgtatagg ctaaaggttt tatccaaagg tctgagacaa
     5461 cgattaggca cgatggaaag aacttttatg tgactgatga cgatcagtgc atcttcctgt
     5521 gtcataatca cagggcacaa gaaagtagga atttgaaaag atgattgacc aactatctaa
     5581 gtattacagt tgtaggatac taactgaaaa ggatattcca agtattttat ctttatatga
     5641 aagtaatcct ctgtattttc agcattgtcc accagagcca aattttgcaa ctgtaaaaga
     5701 ggacatgctt tgtctacctg aaggtaaagc taaggctgat aagttttttg ttggattttg
     5761 gaatggatct gaccttgtgg ctgttatgga ttttgtctat gcatatcctg atgaggagac
     5821 tgtttttatt ggttttttta tggttgatca agcctatcag aggaaaggga ttggtagtca
     5881 tattgtgaca gaagcactag cttattttgc taagaacttt cgaaaggcac gtttggctta
     5941 tgttaaggga aatccgcaat ctcagcattt ttgggaaaag cagggcttta aatcaattgg
     6001 atgcgaggtt aagcaagaac tctatacggt tgttatcgtt gaacagagcc tagaagatta
     6061 gaaatggcat caagtaagaa ctatttggaa tttgttttgg aacaattatc aggattagat
     6121 gatgtgactt accgttccat gatgggggag tatattcttt acttccgcgg caagattatt
     6181 ggcggcattt atgacgatcg cttttagtta aacccgtgca agcagtctta gataagattg
     6241 accaatcttc ttttgagttt ccatacaaag gtgccaaaga aatgatttga gtggaagaac
     6301 ttgataataa gatgtttcta taagacctga ttttagctat gtataaccaa ctgccaacgc
     6361 ccaaacctaa aaagaaaaag caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct
     6421 gtctttgcac gggtaaaatt ttatatataa aaagaagctg ggactaaaga gctcagcttc
     6481 ctttggttta tataattgtc attacaagac gaagtggttg ggcgaaactc tgttgacttt
     6541 attcaattta gagtttctta tgcacaattg agtctggaac gaaagtctcc agttgcaaag
     6601 tatacagtac aataaaccaa cgatgtaata gctgatgaca caaagcacag tgggtaggac
     6661 ttgcgaagtc acccttttct tttcaaaatt tatactaaat cattgatatc agtgtagtca
     6721 cgattaagtc cttgagcaac tggtaggcta gtcaagtaac cttgataagt ggtcacacct
     6781 tgacgcaagc cttcatcttc agagattgct tgtgcgaatc ctttgccagc caaagcttcg
     6841 atataaggaa gagtgacatt ggttagggcg atggttgaag tgcgagcaac cgcaccaggg
     6901 atattggcaa cggcatagtg gagaacaccg tgtttttcat agacgggttc atcgtgcgtt
     6961 gtcacacggt cagctgtttc gataacgcca ccttggtcaa cagcaacgtc aacgatacag
     7021 agcctggacg catttgtttg accatctcat ctgtcaccaa ttccggtgct tttgcaccag
     7081 ggatgagaat ggctccaatc accacatcag catctctcat acttgcttca atgttgaatg
     7141 aattagatat aagagtttga atttgacttc caaagacttc ttctagaact gagagacgct
     7201 tggcactaat atctaaaata gtcacttgag caccaagacc aagggcgatg cgggcagcat
     7261 gtgtaccgac gacaccatca ccgatgatag ttacttttcc ttttggaaca cctggtacac
     7321 caccaggtag aacaccagag ccaccagctt gcttagtaag gaagtgagct ccgatttaaa
     7381 cagccatacg acctgcaacc tcactcatag gaacgaggag cggtagttgt ccttgattgt
     7441 cacgaacagt ttcataggca attcctgttg tttttgctgc taacatagca tctgctaatt
     7501 ctggagcagc ggccatgtgc aagtaggtga agagaagaag aacgtcgcgc aagtaaccgt
     7561 attcagaact taaaggttct tttactttca caaccaactc tgctgcccaa gcttcaccag
     7621 cagtagcgac aatctcagct ccttgctttt gatagtcagc atcagtaaag ccagaaccga
     7681 gaccagcatt tgtttcgata aggacacgat gaccacgact aactaagcta tgaacacctg
     7741 caggtgtgag ggcgacacgg ttttcgttat ttttaatttc ttttgggatt ccgattaaca
     7801 ttgagataac ctacctttca attgacggtc ttgttttggt tgtcacattc cagttcataa
     7861 atcaaaaatg tgacggtttc attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt
     7921 catcccaatt tttttatgct agactagtga aaatcaagct ctaatggagg gaaaagtatg
     7981 gaatcaattt ttgtaaaact tgcccagtat ccgtctatag aaacggagcg tttattgctt
     8041 agacctgtaa ctttggatga tgcggaagca atgtttgact atgcctcgga caagggtaat
     8101 acacgttaca cttttccaac caatcaaagc ttggaagaaa ccaagaataa cattgctcag
     8161 ttctatttgg ttaatccctt gggacgttgg ggaatagaac taaaaagcaa tggtcagttt
     8221 attggaacca ttgacttgca caagattgat tctgttctta agaaggcagc tattggctac
     8281 attatcaata aaaagtattg gaatcaagga ttaacgacag aagccaatcg tgctgtgatt
     8341 gagctagctt ttgagaagat agggatgaat aagttgactg cccttcacga taaggctaat
     8401 cccgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt tttcccatgc agaaccatat
     8461 gcttgtatgg accagcatga aaaaggccga atcgtgacaa gagttcatta tgtcttgacc
     8521 aaggaagact attttgcaaa taaataagca gttgaaaaga aatttttcga ctgttttttc
     8581 ttcctcttac gaataatcta agagaggaga aaatatggaa gcaattatcg agaaaatcaa
     8641 agagtataaa atcatcgtca tctgtactgg tctgggcttg cttgtaggcg gatttttcct
     8701 gctaaagcca gctccacaaa cacctgtcaa agaaacgaat ttgcaggttg aagttgcagc
     8761 tgtttccaag gatttggtat ccgaaaagga agtgaacaag gaagagaagg aagaaccagt
     8821 tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc aaatcgccag ggatttatga
     8881 cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag gctggtggct tgacagagca
     8941 agcagacagc aagtcgctca atctagctca gaaagttagt gatgaggctc tggtttacgt
     9001 tcctactaag ggagaagaag cagttagtca acagactggt tcggggacag cttcttcaac
     9061 aagcaaggaa aagaaggtca atctcaacaa ggccagtctg gaagaactca agcaggtcaa
     9121 gggactggga ggaaaacgag ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt
     9181 caagtcagta gacgagctca agaaggtctc tggcattggt ggcaaaacaa tagaaaagct
     9241 taaagactat gttacagtgg attaagaatt tctctattcc cctaatttac ctgagttttc
     9301 tattactttg gctttattac gctattttct cagcatctta tcttgctttg ttgggctttg
     9361 tttttctgct agtctgtctc tttatccaat ttccgtggaa atctgctggt aaagttctaa
     9421 taatttgcgg aatctttgga ttttggtttg tttttcaaaa ttggcaacag agtcaagcga
     9481 gtcaaaatct ggcggattct gttgaaaggg tacggatttt gcctgatact attaaggtta
     9541 atggtgatag tctatccttt cgtggcaagt ctaacggtcg tgctttccaa gtctattata
     9601 aactccagtc cgaggaggag aaagaagcct ttcaagcttt aaccgacctg catgagatag
     9661 gactagaagg gaagctttcg gagccagaag ggcagagaaa ttttggtggc tttaattacc
     9721 aagcctatct gaagactcag ggaatttacc agactctcaa tatcaaaaca atccagtcac
     9781 ttcaaaagat tggcagttgg gatataggag aaaacttgtc cagtttacgt cgaaaggctg
     9841 tggtttggat taagacgcac tttccagacc ctatgcgcaa ttacatgaca ggactcttgc
     9901 tgggacatct ggacaccgac tttgaggaga tgaatgagct ttattccagt ctaggaatta
     9961 tccacctctt tgctctatct ggtatgcagg taggtttttt catgaatgga tttaagaaac
    10021 ttctcttgcg attgggcttg acccaagaaa agttgaaatg gctgacttat cccttttccc
    10081 ttatctatgc gggactaact ggcttttcag catcggttat tcgcagtctc ttgcaaaagc
    10141 tactggctca acatggggtt aagggcttgg ataattttgc cttgacggtg cttgtcctct
    10201 ttattgtcat gccaaacttt ttcttgacag caggaggagt cttgtcctgc gcttatgctt
    10261 ttatcctgac catgaccagc aaagaagggg aggggctcaa ggctgttact agtgaaagtc
    10321 tagtcatctc cttgggcata ttgcccattc tatccttcta ttttgcggaa tttcaacctt
    10381 ggtctatcct tttgaccttt gtcttttcct ttctatttga cttgaccttc ttaccgctct
    10441 tgtctatttt atttgtcctt tcctttctct atccagtcat tcagctgaac tttatctttg
    10501 aatggttgga gggcattatt cgcttggtgt cacaggtgac aagtagacct ctggtctttg
    10561 gacaacccaa tgcatggttt ttaatcctat tgttaatttc cttggctttg gtctatgatt
    10621 tgagaaaaaa cattaaaaag ctaacggtat tgtgcttatt gattacaggg ctctttctcc
    10681 tgaccaagca tccactggaa aatgaaatca ccatgctgga tgtggggcaa ggagaaagta
    10741 ttttcctacg ggatgtaact gggaaaacca ttctcataga tgtaggtggt aaggcagaat
    10801 cttataagaa aatcgaaaaa tggcaagaaa agatgacgac cagcaatgca cagagaagct
    10861 tgatacccta tcttaaaagt cgaggagtag ctaagattga ccagctgatt ttgacaaata
    10921 cggacaagga acatgtcgga gatttgttag aggtgaccaa ggctttccat gtaggggaga
    10981 ttttagtatc aaaaggcagt ttgaagcaga agcaatttgt ggtagaacta caggcgactc
    11041 aaacaaaggt gcgtagtatg acagtagggg agaacttgcc catttttgga agtcagttag
    11101 aagttctatc tccaaggaaa atgggagatg gaggacacga tgatacccta gttctgtatg
    11161 ggaaattctt ggataagcaa tttctcttca cgggaaattt ggaggagaaa ggagagaagg
    11221 acttgctgaa gcactatcca gacttgaaag taaatgtttt gaaagctgcc caacatggct
    11281 ctaaaaagtc atcaagtcca gcctttctag aaaaactcaa accagagctt actcttatct
    11341 cagttggaaa gagcaatcga atgaaactcc cccatcagga aacattgaca cgactggaag
    11401 gtatcaatag caaagtttac cgaactgacc agcaaggagc tatacggttt aaaggttgga
    11461 atagttggaa aatcgaaagt gttcgatagg aaggataaat gttgtagatt agtgaaataa
    11521 actaaaaatt tgttgcataa taatgataaa aatggtataa tgaaaatgta ttcaatactg
    11581 aggatataaa atcattaaaa attagcaaaa atcgtttaat tagttagttt atgattattg
    11641 gtctttttca gtccagtata tctgctgtga cagtcactaa aagttacaag tatgattgga
    11701 atacggtttg ggaatatagt accaactatc acgaccatca gtatgcttgg attccgtcat
    11761 ggtctcgtta ttacagctat tctgagtatc cagttggttc tggctggaac tacgctcgtt
    11821 atgaggtcat aaactactat actggaggtt attaatcctt aaagagtgag aaaaggaggg
    11881 ctggatatgt taaggcttac tcatgttacc ctaaaaacgc gacaagtcat cttgcaagat
    11941 gtggatttca cctttaaaaa gggtagggtt tatggtcttc ttgctatcaa tggctctgga
    12001 aagacgaccc tgttccgtgc cattagcaat ttaattccca taagtagtgg aaatatcgca
    12061 gcccctcctt ctttatttta ttatgagagt attgaatggc tggatggaaa cttaagtggg
    12121 atggactacc ttcgtcttat caaaaacatc tggaagtcag gtctgaactt gagggatgaa
    12181 atcgcctatt gggaaatgtc tgactatatc agtcttccca ttcgcaagta ttccttaggc
    12241 atgaagcaac gcttggtgat tgccatgtat ttcctcagtc aggccaaatg ctggctcatg
    12301 gatgagatta caaatggctt agatgagtat tatcgacaga agttttttga taggctagca
    12361 caaatcgata gacaagaaca gctggttctt ttaagttccc actataagga agagttggtt
    12421 gatgtctgcg atagagtagt aaccattcat caggggcaga tagaagaggt ttagtttatg
    12481 aaagatgtta gtctattttt attgaaaaaa gttttcaaaa gccgcttaaa ctggattgtc
    12541 ttagctttat ttgtatctgt actcggtgtt accttttatt taaatagtca gactgcaaac
    12601 tcacacagct tggagagcag gttggaaagt cgcattgcag ccaacgagag ggctatcaat
    12661 gaaaatgaag agaaactctc ccaaatgtct gatatcagct cggaggaata ccagtttgct
    12721 aaaaataatt tagacgtgca aaaaaatctt ttgaagcgaa agacagaaat tctgacttta
    12781 ttaaaagaag ggcgctggaa agaggcctac tatctgcagt ggcaagatga agagaagaat
    12841 tatgaatttg tatcaaatga cccgactgct agctctggct taaaaatggg ggttgaccgc
    12901 gaacggaaga tttaccaagc catgtatccc ttgaacataa aagcacatac tttggagttt
    12961 ccgacccacg ggattgatca gattgtctgg attttagagg ttatcatccc aagcttgttt
    13021 gtggttgcga ttatttttat gctaacacaa ctatttgcag aaagatatca aaatcatctg
    13081 gacacagctc acttatatcc tgtttcaaaa gtgacatttg caatatcctc tcttggagtt
    13141 ggagtgggat atgtaactgt gctgtttatc ggaatctgtg gcttttcttt tctagtggga
    13201 agtctgataa gtggttttgg acagttagat tatccctacc caatttatag cttagtgaat
    13261 caagaagtaa ctattgggaa aatacaagat gtattatttc ctggcttgct cttagctttc
    13321 ttagccttta tcgtcattgt ggaagttgtg tacttgattg cttacttttt caagcaaaaa
    13381 atgcctgtcc tctttctttc actcattggg attgttggct tattgtttgg catccaaacc
    13441 attcagcctc ttcaaaggat tgcacatctg attcccttta cttacttgcg ttcagtggag
    13501 attttatctg gaagattatc taagcagatt gataatgtcg atctaaattg gagcatgggg
    13561 atggtcttac ttccttgcct gattatcctt ttgttagtgg ggattctatt tatcgaaaga
    13621 tggggaagtt cacgtaaaaa ggaagttttt aaagtttagt tttcctatag ggaagctaaa
    13681 gaaaaactaa catagggaga gaatcaactt ggttctctct ttttgattcg aaaaccaaac
    13741 caaaatacaa acacaaactt ttcaaaaaat aactttttat cttgacaaga gctagaaaac
    13801 ttggtatcat ataaaagttg agaaaagcag aagtgagagc ttctcgcctt gtgacattaa
    13861 gttgcctggc cctacggatg aaaagtttcg aagaaacgct atcataacgt gcgggcttgt
    13921 atatttacga gtccgctatt gtttttctct aataaaacaa aagaggtgaa aaccatagca
    13981 aagcaagact tattcatcaa tgatgagatt cgtgtacgtg aagttcgctt gattggtctt
    14041 gagggagaac agctaggcat caagccactc agtgaagcgc aagctttggc tgataacgct
    14101 aatgttgacc tagtattgat tcaaccccaa gccaaaccgc ctgttgcaaa aattatggac
    14161 tacggtaagt tcaaatttga gtaccagaag aagcaaaaag aacaacgtaa aaaacaaagc
    14221 gttgttactg tgaaagaagt tcgtctaagt ccaacaattg acaagggtga ctttgataca
    14281 aaacttcgca atgcacgtaa gttccttgaa aaaggaaata aagttaaggt atctattcgc
    14341 tttaagggtc gtatgattac ccacaaagag attggtgcaa aagttttagc cgagtttgct
    14401 gaagcaactc aagatattgc catcatcgaa caacgtgcta aaatggatgg acgtcaaatg
    14461 ttcatgcaat tggcgccagc gactgacaaa aaataattgt cagaaagtta aataaaggag
    14521 aaaaaatcat gccaaaacaa aaaacacacc gcgcatcagc taaacgtttc aaacgtacag
    14581 gttctggtgg acttaaacgt ttccgtgctt acacttctca ccgtttccac ggaaaaacta
    14641 agaaacaacg tcgtcatctt cgtaaagcat ctatggtgca ttcaggagat tacaaacgta
    14701 tcaaagcaat gcttactcgc ttgaaataat agcttgactg taagtaaaca attctaggaa
    14761 atatttggag gaaataaaac atggcacgtg ttaaaggtgg cgttgtatca cgcaaacgtc
    14821 gtaaacgtat tcttaaatta gcaaaaggtt actatggagc taaacacatc ttgttccgta
    14881 ctgcaaaaga acaagtaatg aactcttact actatgcata ccgtgaccgt cgtcagaaaa
    14941 aacgtgactt ccgcaaattg tggattactc gtatcaatgc ggcagctcgt atgaacggac
    15001 tttcatactc acaattgatg catggtttga aattggctga gattgaagtt aaccgtaaaa
    15061 tgcttgctga cttggctgtt aacgatgcag tagctttcac agctcttgca gatgcagcta
    15121 aagcaaaact tggtaaataa caactgatga gactggaaca ggattgtcca gtctttttaa
    15181 aaataaagga gaaagatatg gcttcaaaaa tgctacacac ttgcttacga gtagaaaatc
    15241 ttgaaaaatc aatcgcattt tatcaagatg cttttggttt taaagaattg cgtcgcagag
    15301 attttccaga ccatgccttc acgattgtct atctaggtct tgagggtgat gattatgagt
    15361 tggagttgac ttataactac gatcacggtc cgtatgtggt tggtgatggg tttgcccata
    15421 tcgccctcag tacacctgat cttgaggcac ttcatcaaga acacagtgca aaaggctatg
    15481 aagtgactga gccaaatggt ctaccaggaa ctacaccaaa ctattacttt gtcaaagacc
    15541 ctgatggata taaggtcgaa gtcattcgtg aaaaataatt tcgtgcaagt taagtagaat
    15601 attcgttttc tacttgactt tttttagctg aaagagtata ctaataaaaa ttcaaccttt
    15661 aaggggagtc cagagagact cacaaggtgt cagataaaag aatagtgcaa ttttctagag
    15721 gagacctttt gagtgtgctc tcttgtgttg tacgatttta actgaggcct tgcactagca
    15781 aggtcttttc tttatctggt ccccttaaaa tttaaggagg aaaagttatg aatctcacat
    15841 gtaagaagcg tttgggtgtc attcggttgg aaaccatgaa ggtggttgca caagaggaaa
    15901 tcgcgccagc aatctttgaa ttagtcctag aaggagaaat ggttgaagcc atgcgagcag
    15961 gccaatttct tcatctgcgt gtaccagacg atgcccatct cttacgtcgt cctatttcaa
    16021 tttcgtctat tgacaaggca aacaagcagt gtcacctcat ttatcggatt gagggagctg
    16081 ggactgcaat tttttcaacc ttaagtcagg gagacactct tgatgtgatg gggcctcagg
    16141 gaaatggttt tgacttgtct gaccttgatg agcagaatca ggttctcctt gttggtggtg
    16201 ggattggtgt tccacccttg cttgaggtgg ccaaggaatt gcatgaacgt ggagtgaaag
    16261 tagtgacagt cctcggtttt gctaataagg atgctgttat tttgaaaacg gaattggctc
    16321 agtatggtca ggtctttgta acgacagatg atggttctta tggcatcaag ggaaatgttt
    16381 ccgttgttat caatgattta gatagtcagt ttgatgctgt ttactcgtgt ggggctccag
    16441 gaatgatgaa gtatatcaat caaacctttg atgatcaccc aagagcctat ttatctctgg
    16501 aatctcgtat ggcttgtggg atgggagctt gctatgcctg tgttctaaaa gtaccagaaa
    16561 gcgagacggt cagccaacgc gtctgtgaag atggtcctgt tttccgcaca ggaacagttg
    16621 tattataagg agaaaattat gactacaaat cgattacaag tgtctctacc tggtttggat
    16681 ttgaaaaatc cgattattcc agcatcaggc tgttttggct ttggacaaga gtatgccaag
    16741 tactatgatt taaacctttt aggttctatt atgatcaagg cgacaaccct tgaaccacgt
    16801 tttgggaacc caactccaag agtagcagag acgcctgctg gtatgctcaa tgcaattggc
    16861 ttgcaaaatc ctggtttaga ggttgttttg gctgaaaagc taccttggct ggaaagagaa
    16921 tatccaaatc ttcctattat tgccaatgta gctggttttt caaaacaaga gtatgcagct
    16981 gtttctcatg ggatttccaa ggcaactaat gtaaaagcta tcgagctcaa tatttcttgt
    17041 cccaatgttg accactgtaa tcatggactt ttgattggtc aagatccaga tttggcttat
    17101 gatgtggtga aagcagctgt ggaagcctca gaagtgccag tttatgtcaa attaaccccg
    17161 agtgtgaccg atatcgttac tgtcgcaaaa gctgcagaag atgcgggagc aagtggcttg
    17221 accatgatca atactctggt tggaatgcgc tttgacctca aaaccagaaa accaatcttg
    17281 gccaatggaa caggtggaat gtcaggtcca gcagtctttc cagtagccct caaactcatc
    17341 cgccaagtag cccaaacaac agacctgcct atcattggaa tggggggagt ggattcggct
    17401 gaagctgccc tagaaatgta tctggctggg gcagctgcta tcggagttgg aacagctaac
    17461 tttaccaatc cttatgcctg ccctgacatc atcgaaaatt taccaaaagt catggataaa
    17521 tacggtatta gcagtctgga agaactccgt caggaagtaa aagagtctct gaggtaaact
    17581 gcaatcaatc tgttcttgat tttttattag tttgtaatat gaatttagga gaattttggt
    17641 acaataaata taaataagaa cagaggaaga aggttaatga agaaagtaag atttattttt
    17701 ttagctctgc tatttttctt agctagtcca gagggtgcaa tggctagtga tggtacttgg
    17761 caaggaaaac agtatctgaa agaagatggc agtcaagcag cgaatgagtg ggtttttgat
    17821 actcattatc aatcttggtt ctatataaaa gcagatgcta actatgctga aaatgagtgg
    17881 ctaaagcaag gtgacgacta tttttacctc aaatctggtg gctatatggc caaatcagaa
    17941 tgggtagaag acaagggagc cttttattat cttgaccaag atggaaagat gaaaagaaat
    18001 gcttgggtag gaacttccta tgttggtgca acaggtgcca aagtaataga agactgggtc
    18061 tatgattctc aatacgatgc ttggttttat atcaaagcag atggacagca cgcagagaaa
    18121 gaatggctcc aaattaaagg gaaggactat tatttcaaat ccggtggtta tctactgaca
    18181 agtcagtgga ttaatcaagc ttatgtgaat gctagtggtg ccaaagtaca gcaaggttgg
    18241 ctttttgaca aacaatacca atcttggttt tacatcaaag aaaatggaaa ctatgctgat
    18301 aaagaatgga ttttcgagaa tggtcactat tattatctaa aatccggtgg ctacatggca
    18361 gccaatgaat ggatttggga taaggaatct tggttttatc tcaaatttga tgggaaaata
    18421 gctgaaaaag aatgggtcta cgattctcat agtcaagctt ggtactactt caaatccggt
    18481 ggctacatgg cagccaatga atggatttgg gataaggaat cttggtttta cctcaagttt
    18541 gatggcaaaa tggctgaaaa agaatgggtc tacgattctc atagtcaagc ctggtactac
    18601 ttcaaatccg gtggttacat gacagccaat gaatggattt gggataagga atcttggttt
    18661 tatctcaaat ctgatgggaa aatagctgaa aaagaatggg tctacgattc tcatagtcaa
    18721 gcttggtact acttcaaatc cggtggttac atgacagcca atgaatggat ttgggataag
    18781 gaatcttggt tttacctcaa gtctgatggc aaaatggctg aaaaagaatg ggtctacgat
    18841 tctcatagtc aagcctggta ctacttcaaa tctggtggct acatggcgaa aaatgagaca
    18901 gtagatggtt atcagcttgg aagcgatggt aaatggcttg gaggaaaagc tacaaataaa
    18961 aatgctgctt actatcaagt agtgcctgtc acagccaatg tttatgattc agatggtgaa
    19021 aagctttcct atatatcgca aggtagtgtc gtatggctag ataaggatag aaaaagtgat
    19081 gacaagcgct tggctattac tatttctggt ttgtcaggct atatgaaaac agaagattta
    19141 caagcgctag atgctagtaa ggactttatc ccttattatg agagtgatgg ccaccgtttt
    19201 tatcactatg tggctcagaa tgctagtatc ccagtagctt ctcatctttc tgatatggaa
    19261 gtaggcaaga aatattattc ggcagatggc ctgcattttg atggttttaa gcttgagaat
    19321 cccttccttt tcaaagattt aacagaggct acaaactaca gtgctgaaga attggataag
    19381 gtatttagtt tgctaaacat taataatagc cttttggaga acaagggcgc tacttttaag
    19441 gaagccgaag aacattacca tatcaatgcc ctttatctcc ttgcccatag tgccctagaa
    19501 agtaactggg gaagaagtaa aattgccaaa gataagaata atttctttgg cattacagcc
    19561 tatgatacga ccccttacct ttctgccaag acatttgatg atgtggataa gggaatttta
    19621 ggtgcaacca agtggattaa ggaaaattat atcgataggg gaagaacttt ccttggaaac
    19681 aaggcttctg gtatgaatgt ggaatatgct tcagaccctt attggggcga aaaaattgct
    19741 agtgtgatga tgaaaatcaa tgagaagcta ggtggcaaag attagtacta taagtgaata
    19801 tgatttgagt gaatagtaag ttaaaaatcc tgatttcaag taaaatcagg attttttcat
    19861 ggatgcaatt tttttggagt ctggtgtgac gcggagggtc ttttgtcctg tgtaagtgac
    19921 aaagccgggt tttccaccag ttggtttatt gagttttttg acttcaatca tatctacctg
    19981 caccagattc gacaggcgcc cttgagagaa gtaggcagct aactctgctg cgtctgtctt
    20041 gactgcatca gatgggtcaa gatttcctga gatgacaaca tggcttccag gaatgtcctt
    20101 agcatggaac caaagttcct ccttgcgggc cattttaaag gtcaattcct cattttgaag
    20161 attgtttcgt ccgacataga tgatggtttt gccatcgctt gctagatatt gttctagttt
    20221 tttgcgtttc tggattttct cccgttgtct tctgcggata aaacctgttt gaatcaattc
    20281 ttcacggatt tcagcgattt cttccagtcc agcttggttg aggacggttt ctacactttc
    20341 cagatagaga atagtggctt tggtttcttc aatcaaatca gtcaagtatt tgacagcttc
    20401 tttgagtttc tgataccgtt taaaatagcg ttgggcattc tggttgggag tcagagcctt
    20461 atcaagcgca atcatgatag gttggttggt atagtagttg tctaggataa cctggtcttg
    20521 gtcgttaggc acttggtgta ggaaggttgt cagcaattct cctttttgac gaaattcttc
    20581 agcgttgtct gtcgccagta actctttttc ctgttttttg agtttgtgtc ggtttttctg
    20641 aagttcattt tcaacacgac gaatcagttc actggcctgc tgtttgacgc ggtcgcgctc
    20701 agccttatcc ttatagtagg tgtccaacaa atcagaaaga tttgcaaaag gctctcccac
    20761 ctgatttgca aaaggaactg gactgaagga agtctcagtc aagcatggct tggtttcttg
    20821 attgaaaaaa tttcggaaag cggaaagttt ttcactaacc agtatccttt ccaattcatt
    20881 tgcagtatcg cgtcccagac cttgaaagag gctttgaaga ttttttgctg ttagttcttg
    20941 ggtttgcagg atttcaaaga gcttttcatc tttgatagta aaaggattga gagattctgt
    21001 acttggcgga gcgatatagg tcgatcctgg aagtaaggtg cggtagctat tttgtgaaaa
    21061 accgacgtgt ttgataactt cgaggatttt atgactgctt ttatcgacca gtagaatatt
    21121 actgtgtttc cccataattt caataatcaa ggtagcctgg atatggtctc caatctcgtt
    21181 tttattggaa actgtcattt ccacaatacg gtcattttcc acttgctcaa tcgactcaat
    21241 cagggccccc tgcaaatact ttctcaaaac catgataaag gtagaaggtt gggctggatt
    21301 ttcaaaagtc gtttgggtca gctgaatgcg tccaaaaact ggatgggcag aaaggagcag
    21361 gcgatggctt tggcgattgc tgcggatttg caagaccaac tcttgttcaa aaggctgatt
    21421 gattttctgg atgcgaccat tcactaattc gcttcgcaat tcctcaacta tgtggtgtaa
    21481 aaaaaatcca tcaaatgaca tcgttctctc cttgtgattg tattccatag tattatatca
    21541 aaaaggtaga ataaaatcat ggaaatgtgg tataataaag ccaagtaaag agaaacgaga
    21601 agcacatgta tattgaaatg gtagatgaaa ctggtcaagt ttcaaaagaa atgttgcaac
    21661 aaacccaaga aattttggaa tttgcagccc aaaaattagg aaaagaagac aaggagatgg
    21721 cagtcacttt tgtgaccaat gagcgtagtc atgaacttaa tctggagtac cgtgacaccg
    21781 accgtccgac agatgtcatc agccttgagt ataaaccaga attggaaatt gcctttgacg
    21841 aagaggattt gcttgaaaat ccagaattgg cagagatgat gtctgagttt gatgcctata
    21901 ttggggaatt gttcatctct atcgataagg ctcatgagca ggccgaagaa tatggtcaca
    21961 gctttgagcg tgagatgggc ttcttggcag tacacggctt tttacatatt aacggctatg
    22021 atcactacac tccggaagaa gaagcggaga tgttcggttt acaagaagaa attttgacag
    22081 cctatggact cacaagacaa taaacgaaaa tggaaaaatc gtgacctgat atccagttta
    22141 gaatttgctt tgacaggtat ttttactgct atcaaggaag aacgaaatat gcgaaaacat
    22201 gcagtgacgg ctctagtggt tatccttgca ggttttgttt ttcaggtgtc acgaatcgaa
    22261 tggctctttc tcctattgag cattttcttg gtagtagcct ttgagattat caactctgct
    22321 attgaaaata tggtggattt ggccagtcac tatcactttt ccatgctggc taaaaatgcc
    22381 aaggatatgg cggctggtgc ggtattagtg gtttctcttt tcgcagcctt aacaggcgca
    22441 ttgatttttc tcccgcgaat ctgggattta ttattttaaa cagtaagagg aaattatgac
    22501 atttaaatca ggctttgtag ccattttagg acgtcctaac gttgggaagt caaccttttt
    22561 aaatcacgtc atggggcaaa agattgccat catgagtgac aaggcgcaga caacgcgcaa
    22621 caaaatcatg ggaatttaca cgactgataa ggagcaaatt gtctttatcg acacaccagg
    22681 gattcacaaa cctaaaacag ctctcggaga tttcatggtt gagtctgcct acagtaccct
    22741 tcgcgaagtg gacaccgttc ttttcatggt gcctgctgat gaagcgcgtg gtaaggggga
    22801 cgatatgatt atcgagcgtc tcaaggctgc caagattcct gtgattttgg tggtgaataa
    22861 aatcgataag gtccatccag accagctctt gtctcagatt gatgacttcc gtaatcaaat
    22921 ggactttaag gaaattgttc caatctcagc ccttcaggga aataacgtgt ctcgtctagt
    22981 ggatattttg agtgaaaatc tggatgaagg tttccaatat ttcccgtctg atcaaatcac
    23041 agaccatcca gaacgtttct tggtttcaga aatggttcgc gagaaagtct tgcacctaac
    23101 tcgtgaagag attccgcatt ctgtagcagt agttgttgac tctatgaaac gagacgaaga
    23161 gacagacaag gttcacatcc gtgcaaccat catggtcgag cgcgatagcc aaaaagggat
    23221 tatcatcggt aaaggtggcg ctatgcttaa gaaaatcggt agcatggccc gtcgtgatat
    23281 cgaactcatg ctaggagaca aggtcttcct agaaacctgg gtcaaggtca agaaaaactg
    23341 gcgcgataaa aagctagatt tggctgactt tggctataat gaaagagaat actaagtaga
    23401 ggtaggctca tgcctgcttc ttgtttttac agaaggagga cttatgcctg aattacctga
    23461 ggttgaaacc gtttgtcgtg gcttagaaaa attgattata gggaagaaga tttcgagtat
    23521 agaaattcgc taccccaaga tgattaagac ggatttggaa gagtttcaaa gggaattgcc
    23581 tagtcagatt atcgagtcaa tgggacgtcg tggaaaatat ttgctttttt atctgacaga
    23641 caaggtcttg atttcccatt tgcggatgga gggcaagtat ttttactatc cagaccaagg
    23701 acctgaacgc aagcatgccc atgttttctt tcattttgaa gatggtggca cgcttgttta
    23761 tgaggatgtt cgcaagtttg gaaccatgga actcttggtg cctgaccttt tagacgccta
    23821 ctttatttct aaaaaattag gtcctgaacc aagcgaacaa gactttgatt tacaggtctt
    23881 tcaatctgcc cttgccaagt ccaaaaagcc tatcaaatcc catctcctag accagacctt
    23941 ggtagctgga cttggcaata tctatgtgga tgaggttctc tggcgagctc aggttcatcc
    24001 agctagacct tcccagactt tgacagcaga agaagcgact gccattcatg accagaccat
    24061 tgctgttttg ggccaggctg ttgaaaaagg tggctccacc attcggactt ataccaatgc
    24121 ctttggggaa gatggaagca tgcaggactt tcatcaggtc tatgataaga ctggtcaaga
    24181 atgtgtacgc tgtggtacca tcattgagaa aattcaacta ggcggacgtg gaacccactt
    24241 ttgtccaaac tgtcaaagga gggactgatg ggaaaaatca tcggaatcac tgggggaatt
    24301 gcctctggta agtcaactgt gacaaatttt ctaagacagc aaggctttca agtagtggat
    24361 gccgacgcag tcgtccacca actacagaaa cctggtggtc gtctgtttga ggctctagta
    24421 cagcactttg ggcaagaaat cattcttgaa aacggagaac tcaatcgccc tctcctagct
    24481 agtctcatct tttcaaatcc tgaagagcaa aaatggtcta agcaaattca aggggagatt
    24541 atccgtgagg aactggctac tttgagagaa cagttggctc agacagaaga gattttcttc
    24601 atggatattc ccctactttt tgagcaggac tacagcgatt ggtttgctga gacttggttg
    24661 gtctatgtgg accgagatac ccaagtagaa cgcttaatga aaagggacca gttgtccaag
    24721 gatgaagctg agtctcgtct ggcagcccag tggcctttag aaaaaaagaa agatttggcc
    24781 agccaggttc ttgataataa tggcaatcag aaccagcttc ttaatcaagt gcatatcctt
    24841 cttgagggag gtaggcaaga tgacagagat taactggaag gataatctgc gcattgcctg
    24901 gtttggtaat tttctgacag gagccagtat ttctttggtt gtacctttta tgcccatctt
    24961 cgtggaaaat ctaggtgtag ggagtgagca agtcgctttt tatgcaggct tagcaatttc
    25021 tgtctctgct atttccgcgg cgctcttttc tcctatttgg ggtattcttg ctgacaaata
    25081 cggccgaaaa cccatgatga ttcgggcagg tcttgctatg actatcacta tgggaggctt
    25141 ggcctttgtc ccaaatatct attggttaat ctttcttcgt ttactaaacg gtgtatttgc
    25201 aggttttgtt cctaatgcaa cggcactgat agccagtcag gttccaaagg agaaatcagg
    25261 ctctgcctta ggtactttgt ctacaggcgt agttgcaggc actctaactg gtccctttat
    25321 tggtggcttt atcgcagaat tatttggcat tcgtacagtt ttcttactgg ttggtagttt
    25381 tctattttta gctgctattt tgactatttg ctttatcaag gaagattttc aaccagtagc
    25441 caaggaaaag gctattccaa caaaggaatt atttacctcg gttaaatatc cctatctttt
    25501 gctcaatctc tttttaacca gttttgtcat ccaattttca gctcaatcga ttggccctat
    25561 tttggctctt tatgtacgcg acttagggca gacagagaat cttctttttg tctctggttt
    25621 gattgtgtcc agtatgggct tttccagcat gatgagtgca ggagtcatgg gcaagctagg
    25681 tgacaaggtg ggcaatcatc gtctcttggt tgtcgcccag ttttattcag tcatcatcta
    25741 tctcctctgt gccaatgcct ctagccccct tcaactagga ctctatcgtt tcctctttgg
    25801 attgggaacc ggtgccttga ttcccggggt taatgcccta ctcagcaaaa tgactcccaa
    25861 agccggcatt tcgagggtct ttgccttcaa tcaggtattc ttttatctgg gaggtgttgt
    25921 tggtcccatg gcaggttctg cagtagcagg tcaatttggc taccatgctg tcttttatgc
    25981 gacgagcctt tgtgttgcct ttagttgtct ctttaacctg attcaatttc gaacattatt
    26041 aaaagtaaag gaaatctagt gcgagtaaaa attaatctca aatgctcctc ttgtggcagt
    26101 atcaattacc taaccagtaa aaattcaaaa acccatccag acaagattga ggttttaaag
    26161 tattgtccca aggaaagaaa agtaacccta catcttgaat ctaagtagat tttatggtaa
    26221 aataataggg attttaagga gtttgatatg tataacctat tattaaccat tttattagta
    26281 ttatctgttg tgattgtgat tgcaattttc atgcaaccaa ccaaaaacca atccagcaat
    26341 gtatttgatg ccagttcagg tgatttgttt gaacgcagta aagctcgcgg ttttgaagct
    26401 gtaatgcagc gtttgacagg gattttagtc tttttctggc tagccattgc cttagcattg
    26461 acggtattat caagtagata agaaaataat gggcaggact aggtctttgc ctctttttat
    26521 ttttaaagga tgtttgagaa ggttttacag taaaagaaaa ttaaaaaatc tagaaagaaa
    26581 atatgaaaga tagaataaaa gaatatttac aagacaaggg aaaggtgact gttaatgatt
    26641 tggctcaggc tttgggaaaa gacagttcca aggattttcg tgagttgatt aaaaccttgt
    26701 ccttaatgga aagaaagcac caaattcgtt ttgaagaaga tggtagtctg acattagaaa
    26761 ttaagaaaaa acatgagatt accctcaagg ggatttttca tgcccataaa aatggctttg
    26821 gctttgttag tctggaaggc gaggaggacg acctttttgt agggaaaaat gatgtcaact
    26881 atgctattgc tggtgatacc gtcgaggtag tgattaagaa agtcgctgac cgcaataagg
    26941 gaacagcagc agaagccaaa attattgata tcctagaaca cagtttgaca acagttgtcg
    27001 ggcaaatcgt tctggatcag gaaaaaccta agtatgctgg ctatattcgt tcaaaaaatc
    27061 agaaaatcag tcaaccgatt tatgttaaga aaccagccct aaaattagaa ggaacagaag
    27121 ttctcaaagt ctttatcgat aaatacccaa gcaagaaaca tgatttcttt gtcgcgagtg
    27181 ttctcgatgt ggtgggacac tcaacggatg tcggaattga tgttcttgag gttttggaat
    27241 caatggacat tgtatccgag tttccagaag ctgttgttaa ggaagcagaa agtgtgcctg
    27301 atgctccgtc tcaaaaggat atggaaggtc gtctggatct aagagatgaa attaccttta
    27361 ccattgacgg tgcggatgcc aaggacttgg acgatgcagt gcatatcaag gctctgaaaa
    27421 atggcaatct ggagcttggg gttcacatcg cagatgtttc ttattatgtg accgaggggt
    27481 ctgcccttga caaggaagcc cttaaccgtg cgacttctgt ttacgtgaca gaccgagtgg
    27541 tgccaatgct tccagaacga ctatcaaatg gcatctgctc tctcaatccc caagttgacc
    27601 gcctgaccca gtctgctatt atggagattg ataaacatgg tcgtgtggtc aactatacca
    27661 ttacacaaac agttatcaag accagttttc gtatgaccta tagcgatgtc aatgatatcc
    27721 tagctggcga tgaagaaaag agaaaagaat atcataaaat tgtaccaagt atcgaactca
    27781 tggccaagct tcatgaaact ttagaaaaca tgcgtgtgaa acgtggagct ctcaattttg
    27841 ataccaatga agcgaagatt ttagtggata aacaaggtaa gcctgttgat atcgttcttc
    27901 ggcagcgtgg tattgccgag cggatgattg agtcttttat gttgatggct aatgaaacag
    27961 ttgccgaaca tttcagcaag ttggatttgc cttttatcta tcgaattcac gaggagccta
    28021 aggctgaaaa ggttcagaag tttattgatt atgcttcgag ttttggcttg cgcatttatg
    28081 ggactgccag tgagattagc caggaggcac ttcaagacat catgcgtgct gttgagggag
    28141 aaccttatgc agatgtattg tccatgatgc ttcttcgctc tatgcagcag gctcgttatt
    28201 tggagcacaa tcacggccac tatggactag ctgctgacta ttatactcac tttaccagtc
    28261 caattcgtcg ttatccagac cttcttgttc accgtatgat tcgggattac ggccgttcta
    28321 aggaaatagc agagcatttt gaacaagtga ttccagagat tgcgacccag tcttccaacc
    28381 gtgaacgtcg tgccatagaa gctgagcgtg aagtcgaagc catgaaaaag gctgagtata
    28441 tggaagaata cgtgggtgaa gagtatgatg cagttgtatc aagtattgtc aaattcggtc
    28501 tctttgtcga attgccaaac acagttgaag gcttgattca catcactaat ctacctgaat
    28561 tttatcattt caatgagcgt gatttgactc ttcgtggaga aaaatcaggt atcactttcc
    28621 gagtgggtca gcagatccgt atccgtgttg aaagagcgga taaaatgact ggagagattg
    28681 atttttcatt cgtacctagt gagtttgatg tgattgaaaa aggcttgaaa cagtctagtc
    28741 gtagtggcag agggcgtgat tcaaatcgtc gttcggataa gaaggaagac aagagaaaat
    28801 caggacgctc aaatgataag cgtaagcatt cacaaaaaga caagaagaaa aaaggaaaga
    28861 aaccttttta caaggaagta gctaagaaag gagccaagca tggcaaaggg cgagggaaag
    28921 gtcgtcgcac aaaataaaaa ggcacgccac gactatacaa tcgtagatac gctagaggca
    28981 gggatggtcc tgactggaac tgaaatcaag agtgtacgag ctgctcgaat taatctcaag
    29041 gatggctttg ctcaagtgaa aaatggagaa gtttggctga gcaatgttca tatcgcgcct
    29101 tacgaagagg gcaatatctg gaaccaggaa ccagaacgtc gtcgtaaact cctgctccat
    29161 aaaaggcaaa ttcaaaaatt ggaacaagag accaaaggga caggaatgac cttagttccc
    29221 cttaaggtct atataaaaga tggctacgct aagcttcttt taggacttgc caaagggaag
    29281 catgactatg acaaacggga gtctatcaaa cgtcgtgagc aaaatcgaga tatcgcgcgt
    29341 gtgatgaaag ctgttaatca gcgataaaaa gaggaattga aaatggaaaa attagttgcc
    29401 tataaacgca tgcctttgtg gaataaacaa acaatgcctg aagctgttca gcaaaagcac
    29461 aatacaaaag ttgggacttg ggggaaaatt actgtcttga agggagctct caagtttatt
    29521 gaattgacag aagaagggga agttctagct gaacacctct ttgaagcagg ggcagacaat
    29581 ccaatggccc aacctcaagc ctggcaccga gtggaagctg ccacagatga tgtggaatgg
    29641 tacttggaat tttattgtaa acctgaggat tattttgcta aaaaatacaa taccaatcct
    29701 gttcattcag aggtcctaga ggccatggag acagtgaaac aagggaaagc tttggatttg
    29761 ggttgtggtc aggggcgtaa ttctcttttt ctagcccagc aagattttga tgtgacggct
    29821 gtagatcaaa atggactagc tcttgaaatc ttgcaaagca ttgtggagca ggaagatttg
    29881 gacatgcctg ttggccttta cgatatcaat tcagctagca ttgaacaaga atatgatttt
    29941 atcgtttcaa cagttgttct catgtttcta caagcggacc gcattccagc tattattcaa
    30001 aatatgcagg agaaaaccag tgttggtggt tacaacctta tcgtttgtgc catggacacg
    30061 gaggattatc cttgctcggt taacttccca ttcaccttta aagaaggaga actggcagac
    30121 tattacaagg attgggaatt ggttaagtac aatgaaaatc caggccattt gcatcgtcgc
    30181 gatgagaatg gcaatcgtat tcaactacgc tttgcgacct tactagctaa gaaaatcaag
    30241 taaacacaca tgaagattag gaattttcct gatctttttt cttttttacg aatgatatag
    30301 aaaaggaggg aattcatgtt tgttgcgaga gatgctaggg gagaattggt aaatgtgtta
    30361 gaggataaac ttgagaagca agcatacacc tgcccagctt gtggaggcca gctccatttg
    30421 cgtcaaggac caagtgtacg gacgcatttt gcccataaat ccttaaaaga ctgtgatttt
    30481 ttctttgaaa atgaaagtcc agaacacctg gccaataagg aatccctcta tcactggttg
    30541 aaaaaagaga caaaggttca attagagtac ccgctttcag aacttaaaca gattgcggat
    30601 gtatttgtaa atggcaatct agctctagaa gttcagtgta gtcccttgcc tcagaaagtc
    30661 cttaaagagc gaagtgaggg ctatcgtagt cagggttacc aagtactgtg gttgctgggt
    30721 caaaaactgt ggctcaagga gcgtttgact cgtctacagc aaggttttct ttatttcagt
    30781 caaaacatgg gcttttatgt ttgggaatta gacaaggaaa aacaagtttt aagactcaaa
    30841 tacctgattt accaggatct ccgcggtaaa ctccattatc aaatcaagga attttcctat
    30901 ggtcaaggta gtttattgga aatattgcgt cttccctata agagacaaaa aatatctcat
    30961 tttacagttt ctgaggacaa ggacatctgt cgctatatcc agcaacaact ttattatcaa
    31021 aatctctttt ggatgaaaga acaagcagaa gcctatcaaa agggagaaaa tatcctgact
    31081 tatggactga aagaatggta tccacaaatt cgaccaatag tgggcaaatt tttccagatt
    31141 gaacaagact tgactagcta ttatcagcac ttttatacct attaccaaaa aaatcctcaa
    31201 aatgattggc aaaagcttta tccaccagcc ttttatcagc aatatttctt gaaaaatatg
    31261 gtagaataga aaggatggag gaatctaatg gtattacaaa gaaatgaaat aaatgaaaaa
    31321 gatacatggg atctatcaac gatctaccca actgaccagg cttgggaaga agccttaaaa
    31381 gatttaacag aacaattgga gacagtagcc cagtatgaag gccatctctt ggatagtgcg
    31441 gataacctac tagaaatcac tgaattttct cttgaaatgg aacgccagat ggagaagctt
    31501 tacgtttatg ctcatatgaa gaatgaccag gatacacgtg aagctaagta tcaagagtac
    31561 tatgccaagg ccatgacact ctacagccag ttagaccaag ccttttcatt ctatgatcct
    31621 gaatttatgg agattagcga aaagcagtat gctgactttt tagaagctca accaaagctg
    31681 caggtttatc aacactattt tgacaagctc ttgcaaggca aggatcacgt tctttcacaa
    31741 cgtgaagaag aattattggc tggagctgga gaaatctttg gttcagcaag tgaaaccttc
    31801 gctatcttgg acaatgcgga tattgtgttc ccttatgtcc tagacgatga tggtaaagaa
    31861 gttcagctat ctcatgggac ttacacacgt ttgatggagt ctaaaaaacg tgaggttcgc
    31921 cgtggtgcct atcaagctct ttatgcgact tacgaacaat tccaacacac ctatgccaaa
    31981 accttgcaaa ccaatgttaa ggtgcaaaat taccgtgcta aagttcgtaa ctacaagagt
    32041 gctcgtcatg cagccctcgc agcgaatttt gttccagaaa gtgtttatga caatttggta
    32101 gcagcagttc gcaagcattt gccactctta catcgctatc ttgagcttcg ttcaaaaatc
    32161 ttggggattt cagatctcaa gatgtacgat gtctacacac cgctttcatc tgttgaatac
    32221 aattttacct accaagaagc cttgaaaaaa gcagaagatg ctttggcagt cttgggtgag
    32281 gattacttga gccgtgtcaa acgtgccttc agcgagcgtt ggattgatgt ttacgaaaat
    32341 caaggcaagc gttcaggtgc ctactctggt ggttcttacg ataccaatgc ctttatgctt
    32401 ctcaactggc aggacaatct ggacaatctc tttactcttg ttcatgaaac aggtcacagt
    32461 atgcattcaa gctatactcg tgaaactcag ccttatgttt acggagatta ctctatcttt
    32521 ttggctgaga ttgcctcaac taccaatgaa aatatcttga cggagaaatt attggaagaa
    32581 gtggaagacg acgcaacacg ctttgctatt ctcaataact tcctagatgg tttccgtgga
    32641 acagttttcc gccaaactca atttgctgag tttgaacacg ccattcacca agcagatcaa
    32701 aatggggagg tcttgacaag cgatttccta aataaactct acgcagactt gaaccaagag
    32761 tattatggtt tgagtaagga agacaatcct gaaatccaat acgagtgggc tcgcattcca
    32821 cacttctact ataactacta tgtatatcaa tattcaactg gctttgcggc cgcctcagcc
    32881 ttggctgaaa aaattgtcca tggtagtcaa gaagaccgtg accgctatat cgactacctc
    32941 aaggcaggta agtcggacta tccacttaat gtcatgagaa aagctggtgt tgatatggag
    33001 aaggaagact acctcaacga tgcctttgca gtctttgaac gccgtttaaa tgagtttgaa
    33061 gcccttgttg aaaaattagg attggcataa aatggttgaa tcgtatagta agaatgctaa
    33121 ccataacatg cgtcgtcctg tcgtcaaaga agaaattgta gacttgatgc gtcagcgtca
    33181 aaagcaggtc acaggtttct tgaaagaatt ggaagaattt gcccgcaagg aaaatattcc
    33241 tattattccc catgaaacgg ttgcttattt ccgttttctt atggaaacca tgcagcctaa
    33301 aaatattctg gaaattggga cggctatcgg tttttcagct ctcttgatgg ctgaacatgc
    33361 gccaaatgct aagattacaa ctattgatcg taatccagaa atgattggtt ttgccaagga
    33421 aaattttgcc cagtttgaca gtcgcaagca aatcactctc ctagagggag atgcggtgga
    33481 tgtcttatct acactgacag agtcttatga tttcgtcttt atggattctg ccaagtctaa
    33541 atacatcgtc tttctgccag aaatcctcaa acatttggaa gttggtggtg tggttgtctt
    33601 ggatgatatt tttcaaggtg gtgatgttgc caaggatatt atggaagtcc gtcgtggtca
    33661 gcgaaccatt tatcgaggcc ttcaaaaatt atttgatgca accttagaca atccagaact
    33721 caccgcaaca ttagtgcctt taggagatgg tattctcatg cttcgtaaaa atgtagcaga
    33781 tgttcaactg tctgaaagcg aatgattttc agaaaaattt aagaaaaaat agtaaaatag
    33841 atagagtaac acttatctca aaggagtaga catgaagaaa aaattattgg caggtgccat
    33901 cacactatta tcagtagcaa ctttagcagc ttgttcgaaa gggtcagaag gagcagacct
    33961 tatcagcatg aaaggggatg tcatcacaga acatcaattt tatgagcaag tgaaaaacaa
    34021 cccttcagcc caacaagtct tgttaaatat gaccatccaa aaagtttttg aaaaacaata
    34081 tggctcagag cttgatgata aagaggttga tgatactatt gccgaagaaa aaaaacaata
    34141 tggcgaaaac taccaacgtg tcttgtcaca agcaggtatg actcttgaaa cacgtaaagc
    34201 tcaaattcgt acaagtaaat tagttgagtt ggcagttaag aaggtagcag aagctgaatt
    34261 gacagatgaa gcctataaga aagcctttga tgagtacact ccagatgtaa cggctcaaat
    34321 catccgtctt aataatgaag ataaggccaa agaagttctc gaaaaagcca aggcagaagg
    34381 tgctgatttt gctcaattag ccaaagataa ttcaactgat gaaaaaacaa aagaaaatgg
    34441 tggagaaatt acctttgatt ctgcttcaac agaagtacct gagcaagtca aaaaagccgc
    34501 tttcgcttta gatgtggatg gtgtttctga tgtgattaca gcaactggca cacaagccta
    34561 cagtagccaa tattacattg taaaactcac taagaaaaca gaaaaatcat ctaatattga
    34621 tgactacaaa gaaaaattaa aaactgttat cttgactcaa aaacaaaatg attcaacatt
    34681 tgttcaaagc attatcggaa aagaattgca agcagccaat atcaaggtta aggaccaagc
    34741 cttccaaaat atctttaccc aatatatcgg tggtggagat tcaagctcaa gcagtagtac
    34801 atcaaacgaa tagtccaaat caatgagtca gggaaaaaaa ctcgacttca ggaaaaaatg
    34861 aagcaaacat tcccaaaata aaacgcatag tacaaggttt gtactgcccc caaaagttag
    34921 acaattaatt tatctgaagg atttagttct gtattgcaca gggctaagtc cttttagttt
    34981 taccttaatt ctcttattgt tgtaataatc aata
//
LOCUS       DBERAE010000016        34789 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.16, whole genome shotgun sequence.
ACCESSION   DBERAE010000016 DBERAE010000000
VERSION     DBERAE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34789
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.16"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1040)
                     /locus_tag="ACL70N_000981"
     CDS             complement(<1..1040)
                     /locus_tag="ACL70N_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGS0589799.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPKPAPAP"
     gene            complement(1329..1607)
                     /locus_tag="ACL70N_000982"
     CDS             complement(1329..1607)
                     /locus_tag="ACL70N_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589800.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(1592..1831)
                     /locus_tag="ACL70N_000983"
     CDS             complement(1592..1831)
                     /locus_tag="ACL70N_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589801.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            complement(2288..2485)
                     /locus_tag="ACL70N_000984"
     CDS             complement(2288..2485)
                     /locus_tag="ACL70N_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589802.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLALLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            complement(2964..3692)
                     /locus_tag="ACL70N_000985"
     CDS             complement(2964..3692)
                     /locus_tag="ACL70N_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589803.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            complement(3689..4021)
                     /locus_tag="ACL70N_000986"
     CDS             complement(3689..4021)
                     /locus_tag="ACL70N_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS0589804.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(4077..4979)
                     /locus_tag="ACL70N_000987"
     CDS             complement(4077..4979)
                     /locus_tag="ACL70N_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589805.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(4998..5180)
                     /locus_tag="ACL70N_000988"
     CDS             complement(4998..5180)
                     /locus_tag="ACL70N_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589806.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSIIFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            complement(5187..5561)
                     /locus_tag="ACL70N_000989"
     CDS             complement(5187..5561)
                     /locus_tag="ACL70N_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGS0589807.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(5938..6915)
                     /locus_tag="ACL70N_000990"
     CDS             complement(5938..6915)
                     /locus_tag="ACL70N_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589808.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            complement(7230..8288)
                     /locus_tag="ACL70N_000991"
     CDS             complement(7230..8288)
                     /locus_tag="ACL70N_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589809.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(8445..8690)
                     /locus_tag="ACL70N_000992"
     CDS             complement(8445..8690)
                     /locus_tag="ACL70N_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589810.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(8671..8796)
                     /locus_tag="ACL70N_000993"
     CDS             complement(8671..8796)
                     /locus_tag="ACL70N_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589811.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            complement(9170..9382)
                     /locus_tag="ACL70N_000994"
     CDS             complement(9170..9382)
                     /locus_tag="ACL70N_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589812.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            complement(9536..9970)
                     /locus_tag="ACL70N_000995"
     CDS             complement(9536..9970)
                     /locus_tag="ACL70N_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589813.1"
                     /translation="MGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVY
                     IFLGYVLVIQKDVYLFSILIIFSNFSVPFIREKEYELFKNKK"
     gene            complement(10009..10347)
                     /locus_tag="ACL70N_000996"
     CDS             complement(10009..10347)
                     /locus_tag="ACL70N_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS0589814.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            10813..11676
                     /locus_tag="ACL70N_000997"
     CDS             10813..11676
                     /locus_tag="ACL70N_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0589815.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(11889..12281)
                     /locus_tag="ACL70N_000998"
                     /pseudo
     CDS             complement(11889..12281)
                     /locus_tag="ACL70N_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase domain-containing
                     protein"
     gene            complement(12298..13104)
                     /locus_tag="ACL70N_000999"
     CDS             complement(12298..13104)
                     /locus_tag="ACL70N_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0589816.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(13311..13952)
                     /locus_tag="ACL70N_001000"
     CDS             complement(13311..13952)
                     /locus_tag="ACL70N_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589817.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(13949..16057)
                     /locus_tag="ACL70N_001001"
     CDS             complement(13949..16057)
                     /locus_tag="ACL70N_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS0589818.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(16109..16360)
                     /locus_tag="ACL70N_001002"
     CDS             complement(16109..16360)
                     /locus_tag="ACL70N_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS0589819.1"
                     /translation="MVCGILATTNALAVWVEGGQWNYGVGWTGTFGYSDYLHSTRYHT
                     ATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            16804..17130
                     /locus_tag="ACL70N_001003"
                     /pseudo
     CDS             16804..17130
                     /locus_tag="ACL70N_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(17182..17769)
                     /locus_tag="ACL70N_001004"
     CDS             complement(17182..17769)
                     /locus_tag="ACL70N_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS0589820.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQKLVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            18011..18682
                     /gene="sdaAB"
                     /locus_tag="ACL70N_001005"
     CDS             18011..18682
                     /gene="sdaAB"
                     /locus_tag="ACL70N_001005"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGS0589821.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            18691..19563
                     /gene="sdaAA"
                     /locus_tag="ACL70N_001006"
     CDS             18691..19563
                     /gene="sdaAA"
                     /locus_tag="ACL70N_001006"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGS0589822.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            19585..20217
                     /locus_tag="ACL70N_001007"
     CDS             19585..20217
                     /locus_tag="ACL70N_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0589823.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            20267..20524
                     /locus_tag="ACL70N_001008"
     CDS             20267..20524
                     /locus_tag="ACL70N_001008"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589824.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSNHIRQGDVDVI"
     gene            complement(20610..22460)
                     /locus_tag="ACL70N_001009"
     CDS             complement(20610..22460)
                     /locus_tag="ACL70N_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGS0589825.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(22502..23659)
                     /locus_tag="ACL70N_001010"
     CDS             complement(22502..23659)
                     /locus_tag="ACL70N_001010"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0589826.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVINNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            23717..24883
                     /locus_tag="ACL70N_001011"
     CDS             23717..24883
                     /locus_tag="ACL70N_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGS0589827.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            25022..25348
                     /locus_tag="ACL70N_001012"
     CDS             25022..25348
                     /locus_tag="ACL70N_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS0589828.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEHLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            25335..25928
                     /locus_tag="ACL70N_001013"
     CDS             25335..25928
                     /locus_tag="ACL70N_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGS0589829.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            25921..26832
                     /locus_tag="ACL70N_001014"
     CDS             25921..26832
                     /locus_tag="ACL70N_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGS0589830.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            26895..27959
                     /locus_tag="ACL70N_001015"
     CDS             26895..27959
                     /locus_tag="ACL70N_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGS0589831.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(28031..28891)
                     /locus_tag="ACL70N_001016"
     CDS             complement(28031..28891)
                     /locus_tag="ACL70N_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGS0589832.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(29013..29999)
                     /locus_tag="ACL70N_001017"
     CDS             complement(29013..29999)
                     /locus_tag="ACL70N_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGS0589833.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(30271..31746)
                     /locus_tag="ACL70N_001018"
     CDS             complement(30271..31746)
                     /locus_tag="ACL70N_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0589834.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(31830..32753)
                     /locus_tag="ACL70N_001019"
     CDS             complement(31830..32753)
                     /locus_tag="ACL70N_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0589835.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(32767..33696)
                     /locus_tag="ACL70N_001020"
     CDS             complement(32767..33696)
                     /locus_tag="ACL70N_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589836.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(34015..34365)
                     /locus_tag="ACL70N_001021"
     CDS             complement(34015..34365)
                     /locus_tag="ACL70N_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589837.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT        10997 a         7165 c         5722 g        10905 t
ORIGIN      
        1 ggagctgggg ctggtttagg agccggagct ggagtttctg gctcatcaac tgctttctta
       61 aggtcagctt cagtattttc taattcagct tttttagcat ctaagtcttt tttagctgca
      121 acaagatatt gttcagcttg ctcaccgtct gagtttttga aatcttctac atctttttca
      181 agttttgcaa tttcagcgtc taactcatca atcttatcac tcaactcttc aagttttgat
      241 agtttagctt ttttggcatc caatttagat tgaagaggag cacggagacc ttctttaata
      301 taatcttctg agtcagactc atcaatctct ttgagctctt tttctagtcc ctgaacttca
      361 tattccaact cagcgatttt agcttcaaga gcatattttt cagcatccac tttttgtttg
      421 gcttcaacag cttttttctc agcttcttct gcttttgctt tagcttctgc tactttttta
      481 gcaagttctg gttctttttt ttcagcctgt tctgcttttt tcttagtctc agctaactta
      541 tctgcttcag gaactacttt tgcttgttcc ttattgaaat tcgcttccgc ctctttttgt
      601 tttaatgtta cctcatcaat atgagctaat gcatctttta atttctgttg agcggcattt
      661 ttcttattgt ttggactttt gttcaattgt tcttgtgctt ctcggagttt taaatacgcc
      721 ttttgaactg ccacattcgc tttttgacgc tcttcatccg ctttttgaac aagctttgct
      781 ttctcttcag ttttcttttg atcgtcttca tattttttct gagcagcttt tgcttcttct
      841 aaatctttct tagcttcttc gtattctttc ttagcagctt cagatttttt cattgctgca
      901 tcatagtctc tctcagcttg agactgctta gctacgggag cttcttctgc tcttacaaca
      961 gtaggctgag acgcaacaaa accagcccct aagatagcga cgctggctag acttgttaaa
     1021 atcatttttt tcttattcat ctaaatttac ctcttttctg atagtcattt ttagactata
     1081 cttatattaa gtatactccc cccgtaaata tttgtcaaat gttttatatt acatttttat
     1141 tacaaatttc tatatcataa gcttctactc caaaaaatag ataaagatac tacttttgcc
     1201 cttttcgatt ctctttttaa acatagcatc atcttccttc attcctataa aaacatttcc
     1261 gatgagagag cttgtttttt aatttcgtta aacaacaaaa aacgcaagct taagcctgcg
     1321 gacaatcttt atagccattt catttctttc acatctgttt tacgaacttt agcatatttc
     1381 ttagcgcttg taaaatgtag agtaactgat ttaaatactc cgcttttgtc tcttcgtaaa
     1441 cctaaaactg cggatctttt atttttatcc tcaaaaaata tgacgtccaa tttcatagta
     1501 tttttagata aatccctagc tacgatgcaa caacttatta ttttagaata gaaaatatca
     1561 ccgataaact catataaaga tatcctttcg attacatcat tgtacatagg atatttctaa
     1621 aatcttctaa aataaaaaca ccagcttgaa tagcaggttt tgtttgacta gcataatctc
     1681 gtgtgatttt gtataagtca aataaatgat gtaaatcagt caagcaaaaa ttcactttga
     1741 aaatctctaa atacttataa ttcgttgata cttgacatgt ttttccattg aatctttctt
     1801 gatagtccaa aatacaatca agtaatttca acgacaaact ccatattttc tcaaaataaa
     1861 aaagcacggg gcagttctca ctactgccca aagtggttga ttagagtcgg cttctctaac
     1921 tccctatgtt gtgcttatta ggcttatcgc aagggaacag tttttagctc tgccaagcca
     1981 catagtgtgc ttactactat gtgtccatgt caccatgaat tgccgaacgg tttaacgaga
     2041 aagtatagta gattgaaaca agatgtgaac aaatcgatta ggaaagtcaa attaatttct
     2101 agaaatattt taacagtcat aacggactat tccagattca atctactata ttacttttag
     2161 gtttatccca actcaattat gacatttttt tcaaaagtca atatatctca ctcttttcaa
     2221 cgacaagaaa gaggctgata atcgaccaac ctctgttttt agatacagtt caagtccaaa
     2281 ctattcttta tagaaaagtc cgataaattc gagcaatagt taacatactt acaaatataa
     2341 ctcccaaaat agataacact attttcacaa aactcagttc cgaacctatg acatatatat
     2401 gaaaaagaag ggctagtcct acacatatat acaataagta gccaacaagt tttatctcac
     2461 caattcctgc aaaaaaatgt ttcatgtgac gattctccat ttactccatt aaatcagttt
     2521 tattttagac tatcataaca caatcacctc ttcaataaaa accatttgcg aaatactatt
     2581 ctgaagcatt gatagctcag atttctcaga atagagctgt cctaactatc gagcagctca
     2641 aatacatata tatgagcaat tctaagccta gaattgctat aaaataaatg tttccaggct
     2701 attctaagtc tttgactgct taaaatttta cattctgaag gattctaaag ctagaacagc
     2761 tcaaaatcac gagaactaag gtattcgaaa cttcagagta atacaatccc cataggaatt
     2821 ctccattctt attaagcatg attaaaatgt aatcctaaca agtgatcctc gactgtgttt
     2881 gtagcactta gttacctaga taagactatt tccctttatc atatctgatt ttaagccgtt
     2941 ctaagattta acctatgttt ctattacttg ctatttttaa ataattcgta ttcctttgct
     3001 ttgataaatg gaactgaaaa attagaaaaa agaagtaaaa ccgaaaacaa atagcctgct
     3061 ttttgaatca ctaaaagata tcctaaaaat aagtaagcta taacatccaa tgcgaaaaga
     3121 aaaaatattc tcctcttcat taaagtactt gtgtcaaata atctgatgaa taaaaatttt
     3181 atcgtagtat ctacacaaat ttttatcaaa aagataagag ccaatacacg attatcaact
     3241 gtaccgtaaa gaatagatgg aaatatagtt aatataaaac tagaaatctc taaatatttt
     3301 atccaagaag attgagacac cttgcttcta aactgactaa ttttcttata ttcgttagtc
     3361 aatttagtag caaaatcttc cccaattaaa tgaaagattg ctaactctag gataaaaaca
     3421 cttattaata cggtataagt caaaaaactt tctgggaaaa acttattgat taaaatgggg
     3481 aaactcatta acagaatcga atttatggct agacagatag atactatttt atttttcaca
     3541 gaatatagag gtagtgatac tattgagtag ataaaagcta aaaaaataag caaaaaatac
     3601 tccgtgtcat ttataatcgc cctgaatgat aaaaatatat acacccaaca tacgataata
     3661 tgtatttttc gaatcttatc tacattattc atcttactgt cgcagatata aatccatccc
     3721 aaggataagg gttcccgcta atatcacaac ctctattaag agcaccatat ccaatacagt
     3781 aagctatttt tcctgctgct gcaccaataa gccagcctcc aagacctcca accttaatat
     3841 agtttattag ttttttggtt aaaactgcag ctccagctaa tgctataaaa gttcctgaac
     3901 tcatagctaa agctacgcaa attccttgac aagcacgctt gcttaaataa gctcccccat
     3961 caagatacat catttcttct tcatcaatca caacataatt atttggtaat acaagttcca
     4021 tttgttttct cctccttagt tgaaattgtt tcatttgttt tacaaatagg acgaacttaa
     4081 actatctttt tattactcag taataatttc cgagatttca ttttatgata ctctctattc
     4141 atacagaaat caaaattttg ccttaaccaa cttgtataat agaaaaaatc taattgattg
     4201 attctgatga ggtgtatcct aattttatca accttgttgg accagttgtt attgttacta
     4261 atagacattt catacagcag taactcgaca agacctgtac acagaagggt gttatgagaa
     4321 tcttcgattt ttttcaaaat atcctcaaaa agttcactat ccgttaaaaa ggtggattgg
     4381 ttcatcgcat catacagctg aagagacatt aagtcagaat aacttagctc tgatttttgt
     4441 atcttatcct ttaacgtttt cgtcaaatcg ctttcaaacg aatcttcttt ttcccattta
     4501 ttttgattaa aaagaaattc cgtcttatta aaaacgagat gattgatatc cattatagtc
     4561 cagaaaaata ttgtagtaag catgatgatt gcaaaaggaa tttttaaaat aaatactaga
     4621 ataatagcaa tttcaagaat aaaactccat ataatcctag atcttaaatc atcaggcgac
     4681 aaacttttac gatggaatga aaaatagggc gagaacctca catttacttt cttcctgcct
     4741 ataaaaataa aaggaaaaat cgtaataaga gcttctttct tgtacaaatc tttcaatgcg
     4801 tatagtatgt ctaaaactat ttttgataaa atcaaactac agaaagcaag actcgtacta
     4861 accacaaaat caaggggaat ttctagattc aattgcaagt tactcactaa caaatgcaac
     4921 tctagccaca agacaaaaag agggagcatt aataaaaaaa tgattagttt acgtatcata
     4981 attttacagt gtccttatca ttttcttaat tttggataaa ttatcattgc tatgattaaa
     5041 atcaaaaaaa cgacattcat ccaaataatc aactttttta tttcttcgct aacaaaatca
     5101 taggctaaaa aaattatgga tgatataaat agacatacaa aaaaaataat aacaaaaatt
     5161 ttttccattt taatacccat atctagttac cacaaggcgt ttaaatttgg gtctctccta
     5221 tttacatcat tgttggccca gattgttgta atagcatcgc caattgacat ccaagctgca
     5281 aatccattaa tagcagacag tgcaaatcct gccactctat ttgcaactcg taccccaaca
     5341 tatcttgcag ctgctccagc aattgcgctt gtaactcgcc gcaaaccata attacgaata
     5401 taatttctaa ctagactgat tgctcctcca cctaaaacac cattaaaagc tatattaatg
     5461 gctgttgcaa caggccatct cagaatagaa aatcccccat caagatacat catctcttct
     5521 tgctcaagag caacataatt atttggtaat acgagttcca tttattttct ccttttttat
     5581 taagcatagt taggatcgtt tcctaacaag tgatagacga ctgtgttttt atcacttagc
     5641 tacctagata agatatcctt tctctacctt atttgttttt ataggttacc taaggtttaa
     5701 aatcaattat tgtttgaaac ttaacagttc taaaccacta gcaataaatg attgcgaact
     5761 cactaatact atttcaaaat ttattttttt tgacttagta acgcaattcc aattagcaat
     5821 acacctaata taaataaaag tatttcccaa aatttattct cagttttaat aagtggaata
     5881 agatacatac tgactaatat gcaacttgcc cctataatgg caaatattat tctagtttta
     5941 tctcctaatt gaaacatgtt tgatccctat atacacttca agcaaaagtt ggatttctga
     6001 aatggctaaa gataaagata atggttgcga gctatttaaa ctatcatcaa tattctgctc
     6061 gattaaaaca aagtctggtc ttacctctaa aattttcttt aacattgatt catatttatt
     6121 tttttcatta taatgccgta aatatagatt taattttata acatccaaca taccataaag
     6181 tgatattgga ttatttattt ttttaaatcg cttaacttct aataaatcaa tttgttcacg
     6241 cacactctct gaaagatatg gcttgattaa actgatataa gataaagcca cgcatggcaa
     6301 ctcagatttt gattgcaatt tccaaatttc atgataatcc tgaagattaa actcacaatt
     6361 cttcttagat tccagtattg ttagtacctt tgattttaac agaaataatt gttgattctc
     6421 aattctataa agtttttgta ctaatgctat gataatagaa aatgaaataa gaggcaaaag
     6481 caacggtttg tcatacacaa aagtaaagaa aaaatagtat gaaattagtg ttgtaaagta
     6541 caagaagtag taaaatttaa acagattctt agttgtttga ctctccttat aaaacactgc
     6601 tattcctgga ctaaatccca ttagttggtg aaagagaatt cgatagtatt tcctagctcc
     6661 tataatgatc acaaatataa aataaaaata aattggtctt aatttacaaa agattgagga
     6721 aactagtaat agcaaagtat gtaagcattg agacaaaata tagaataacg gtatcgccaa
     6781 tacaaaggtt aagatggcat gagagggagt tcctaagatg tccaatttta taaatactgg
     6841 gctgacacaa aatatcgtgc ttataagcag taaaattatt aaaattgtgt caaaaaaata
     6901 acgcttattt ttcatttagt ctactttcca ttgttaaata atactactgt taacaccaag
     6961 ccaacttagc acattgcatc acctaatcct acgctacttg tccataatcc tttaatgttt
     7021 ctactaaaat tattccaatc tcccccatca agatagctta tttatcctag acaacgccta
     7081 ctgcaacagt ataaataaga ttcatcagcc atcttttctg gcaatcatat gggtagacta
     7141 atgatatttc tagttactca aaaatatcta gctatactag agttatttct aatccctagg
     7201 acacttgtta atccaaatgt aacaaatttt caccccttaa taggactctt tctggaaaaa
     7261 atataaggtc tatctttata aaaaaatcta tcatattggg atggcatgca tctggaattt
     7321 aaacaagcta taaattcatt tataactact atttgtttag aggcaacagc atcttgtata
     7381 ccgccctcga aagaaccatc ttgtaattcc gaaatatttt tgtttaaata ttgttttgac
     7441 aaatctctta atgcttcatt atcgtaaatg attcccaaaa atccaacctt atatagtaaa
     7501 taatttaaac ttacaaagta attgaatccc atagtatatt tttctttata aagcaaaggt
     7561 aaaactttat aaaaaatatc taagtcaacc tcactctgat tctgaagcaa gtaggagtca
     7621 agcaaatttt caaaaatagc taacaatatg attggtgtaa agtttttgta ttcacatgtc
     7681 aagtattctg agtatcgtgc agatgatatt tcttttatat aactttttga aagcaagatt
     7741 ttttcaaatt catcatctat tattaatctt ctatttccaa tccaagcggt attaccaccc
     7801 aaataagatt gtacaaatag caatatataa gaaaacatga acgtaaatac tgaaaaaggt
     7861 agaattctat gcgtaaaaaa atagacgata atggtagcca ggagtaaaga tatctctcgt
     7921 gacaatcgaa ttcttttcag catctttttt aacagtccgt aaggttgtcc ttggcaatat
     7981 tcttgaacta aattaatcgg aatgacatct ctcaccattt ctggaaagta gagtaagttt
     8041 ataggttgaa atctccagct cccatcataa gtaaatggat atagaaccaa atacttaaaa
     8101 gatttttttc ttataaactt aattatcaca atatgaatga ctgttgcaat gaagtatatt
     8161 aaatataaaa gtaaaaccgc catcaatata cttacaaaaa tccccttgga atcaatcaat
     8221 ggaaaataaa atattgcaac tagaagcgaa taaagtcccg ctaataaata tttctgatca
     8281 tctttcattc aaaacaccat attatttact aagaatgcat caatacaata gagcaactct
     8341 gtaagtcaat atttgataaa gcaaagcttt aaacccttcc ccagacgtta gcttttattc
     8401 aacccactac agttgacaag gagcccaaat tattgataaa aactttagtc atcatcgtct
     8461 ctataaaaat attttctata cactcttgat aataccaaaa ttaatgccaa tatcatacca
     8521 agagctataa taatagaatt tattagattt attttagtat atccaatcac tagtccaata
     8581 attggactag cagacatgct tagatataat aaaaataaca aaaaatgaat ttcaccaatt
     8641 cctgcaaaaa aatgtttcat agctatagtt ttacgcccat aaatacccat caaatttacc
     8701 gtctacgata tctaaaccat atgcaatggc tcctcctaat gagaagactt cagcaacagt
     8761 agccgcaata ttaagagcat tagtaatagt tgccatacta actccaccaa tatatcttgt
     8821 tatagcactt agttacctag ataagatatc ctttagcttg cttccaaaat ttaagtctac
     8881 acctataata tgagttcata ttagtactgc taaatcctat ctatagtaat gtcaaacacc
     8941 taaataaagt catctctcca attcattcaa gaaatgaaga aaggcaaaaa atctttaaaa
     9001 taagaaaaat gcatattatc aggtgttcaa aaatattgat gatatacgtt atatagatag
     9061 aaagatttac tcaatctcat tttcaaattg agttttttcc cagcctcatt tttaatttat
     9121 atcttcaata gaatctaatg accgagctac tgtattacac agattaatat tatttagtct
     9181 gtaatttttt taaaaaactt aatagtaaat ttgctccact gattgctatc aatatttcaa
     9241 ttggtaaaaa atagtaattc caaataaaat gagaaatcag caatgataga aaaataacaa
     9301 tatcaatttt cctgttgttg acatactctg taattttatg atacagtaat gcaacaataa
     9361 ctgaaattaa aacaatcaac ataatactat tatcctatcc ttctcactaa ctctatttcc
     9421 aaaatttaat ttttggggga cttagtaatg aaattacaat taacaacaca cctaaaataa
     9481 ataaaaatat ctcccaaact ttattctcag ttttaataaa gctaccatat ctatctcatt
     9541 tcttattttt aaataattca tactcttttt ctctgataaa gggaactgaa aaattagaaa
     9601 aaattatcag aattgaaaac agatatacgt ctttttgtat cactaaaaca taacctaaaa
     9661 atatatagac catcaaatct agtacaaaaa gagaaaatat cctccttttc attaccttac
     9721 ttgccttaaa gattctgttt aatagaacct ttatcgtagt atctacacaa atttttatca
     9781 aaaagataag agccaataca cctgctgctg caccaataag ccaacctcca aggcctccaa
     9841 ccttaatata gtttattagt ttttttgtta aaactgcagc tccagtcaat gctataaaag
     9901 ttcctgggct catagctaaa gctgcgcaaa ttccttgaca agcactcttg cttaaataag
     9961 ccccccccat caagatacat catctcctct tgctcaagag caacataatt atttggtaat
    10021 acgagttcca tttattttct cctttatact atgtaatacc acaaaatgat tttgacctaa
    10081 atcattctta acttgaagaa tcgcaggaaa tgttaatttt ggagtcaaat cttccagtgc
    10141 cactcgaaca gcttttactg taaaattcaa cttattcaga cctgaaacaa taccactgac
    10201 agtcgttcca tacatgtctg taccaataat ttcccgaatc ttcatgattg atagttcctt
    10261 tttgtaagat aaaagaactg ttgaaacaac tgccgcagca caatctgact gatcatgttg
    10321 catcgtacaa ggatattttt ttaacataga aatactcaat tctttagaat taatctaact
    10381 tttctttgat gtcacccaaa cctcaatcac tgcccagtag ttcttgaatc agtttatttt
    10441 caatcgtatc attctttgtt cttgatatct ttccaagcat tgtagtacag cagatttttg
    10501 tccaaggact gagcctcctt taacaactca agctccctta cattatatcg accagcccca
    10561 tggaaagatt atgaccagac taatcaatga tatcatacat actagaatac aaaatatttt
    10621 tttattcata ctttttctcc tatctttatt ttctacctac atcatacctc ttattaagct
    10681 cattttaaaa ttacgttaac ttttttcaca aatttatttc gactttcttt tttacttttt
    10741 acattgctat gatacaatat ttttaacaag attttattat ttgttaactt ttttcacaga
    10801 aaggagaaaa tcatgcgtta tgatttcgga aaggtctata aagaaatacg tgagtcaaag
    10861 gggctgaccc aagaagaggt ctgtgggggt gttctctcaa gaaccagctt atcaaaaatc
    10921 gaaagtggca agacaacccc aaaatatgaa aatatggaat ttcttctccg tcaaatcaat
    10981 atgagttttg aagagtttga atatatctgt caactttatc aaccaagtca acgcacagag
    11041 attatgcaaa cctatctcaa tatgcgttcc attatcggga ccagcgatct tgtcaattta
    11101 tttcaaaaat gccaagacta cctcaagacc caccacgatc tccctataga agaaatcaga
    11161 gatatgcttg aagttgtcat ttatatccgt caacacgggg caggggaact atcagatcac
    11221 gcagaacagg ttgtcaaaaa actttggaga aaaattgaaa aacaagatac atggtatgag
    11281 agtgatctaa aaatcctcaa taccattctt ttcagttttc ccattgaata cctccatctc
    11341 atcactggaa aaatattgca acgcctagaa gtctataaaa actatcaaca tttatatgac
    11401 ttgcgaatag caatcctgct caacctttcc acactctatc tatacaatca agataaaaac
    11461 atgtgtaagc aaatctgcta cactttactg gaggacgcca agaataagaa aagctacgat
    11521 aggctggcta tctgctatgt ccgcattggg atttgtacag acgattctaa acttatccaa
    11581 aaaggtttct cactcctaga gctgaccgag gaaacttcta tgctgtctca tctcaaaaaa
    11641 gaagtagaga tctattacca agcgaaggaa agataaaaaa gccgagggag ctcctcgacc
    11701 ttttcataga atcgccgaac gatttaacga gaaagtatga cttttacgtt tatcccaact
    11761 caattatgac atttttttca aaagtcaata tatctcactt tttcaacgac aagaaagagg
    11821 ctgataatct accaacctct tattctgaac ccatcactcc atcacttttt agcttcattc
    11881 gctttcttag cgactgcaat ctggtattcg acttggtcat tccccttacc ggtacaacca
    11941 tgagcaattg tagtcgctcc tatctgatgc gctatttcaa ccaatttttt agaaatcaga
    12001 gggcggctca aggcagatac caagggatac ttttgttcat aataggcatg tgactgaaga
    12061 gccactagca cataatctgt agcaaattcg tccttaacat caatgacata agattctact
    12121 gccccaacct taagagcctt atcatggatg aaatctaagt ctttcccttc acccacatcc
    12181 atacaaactg aaacaacatc atagtctttc tttaaccagg taatagcaac tgatgtgtcc
    12241 aaaccgccag aataggccaa aattactttt tctttactca tgttcttttc cttctttcta
    12301 tttttcaatg gatgctttaa aggcatcctc aatgagtttg tctaattccc cagactcctt
    12361 caacttttga atggttttat cgactgcctc tttcaattcc ttgctatctt ttttcatggc
    12421 taccgcgtag gaatcatctt gctctttttc aaaattgagg tctgcgattg ctaaatcagg
    12481 attattttcc acaaatccct tggaaacagg ttcttcaaag ataacggcat ccacttgtcc
    12541 tgattttaaa tctgtgatta aattcccatt tttaggcaga gatacgaggg aagaattttg
    12601 tagcaaatct ttcgccatcg tctcttgaat cgaacctttc tgcgctccaa cctttttctg
    12661 cgccaagtcg tttacagact gataagtagt caagtcagat tttttgacaa tgagtttatt
    12721 ttttgcagta tagtagggaa tggaaaagtc aaacaccttg ctccgttcat ctgtcttaga
    12781 aacacctgat atggcaaggt cggcttttcc tgattgaaca ctagccagta cattatcaaa
    12841 actcatggga gatagttcca attcgacacc tagttctgtt gcgatagcct tggctaattc
    12901 gatatctgaa cccacaatct gatttttccc atcaaccact ttttggtatt caaatggagc
    12961 aaaatccgga ttgagggcta caaccaattt tcctttggac ttgatggctt caattccagc
    13021 cgattgattg ttgctacaag caaatagtag ggggagcatc actaaaccaa acatcgtcat
    13081 caacaccttc ttcatcttat tcataataaa gcctacttta tgtttattcc ttttgtttgt
    13141 ataaacaata catctatatt catcctttgt caagcctaaa ttgaaaaaat tttcaatttg
    13201 aaacaaaaaa aacctagaaa tactacataa aatgtcattc ctaggcgtat ttatgctatt
    13261 tttctctgga aaacatgagt attcagccag tcaaaaggag ctgaatgaac tcattttccc
    13321 tcgcccaatt caatgacacg atgacattgt tgggctacat aagcatcgtg ggtcacaata
    13381 atgactgttt tcccttctcg attcatctct aagagaaact tcaagaccaa atctctattt
    13441 tcaggatcca gcgaacctgt aggttcatcg gctaaaatca gctggctggg ttttaagatg
    13501 gctctagcaa ctgcaattcg ttgttgttcg ccaccagaca actcggagac cctttgatgc
    13561 aaagtagctg acaaacctac tctctctaaa atctcttcca cctttttgag cttgtctttc
    13621 ttaggcaatt tcacatattt cagcgccagc atgagattgt actcgaccgt ttcatcatca
    13681 atcagggcaa aattttgaaa cagataagag atatgttcac ggattattgt ttgcgactta
    13741 gcagaattaa ccgctagatt tgtctgacca aaaatctcat accgtccgct ataatcacca
    13801 tctatcaaac ccaataaatt taacaaggtc gacttcccac taccactctt accaacaata
    13861 gctaccaaat ccccctgatc aatcctgaga gataagttat ccaaaatcac ttttccccca
    13921 atggttttgg taatattttt caactcaatc ataagatgcc ccctttcaat aactctacta
    13981 gacttctttt ctccatccta gaagctaagc ctagcacaaa tagtatatcc agacatgtaa
    14041 aacctgcaaa cagtagaagt ggtaagaacg catgggcaaa gaaaatcaag actagaagag
    14101 ggaaactata gcccagcaag agcagaacga ggagaggacg gtagcgatcg accagtttcc
    14161 accccataaa cttcttggta atgatatccc tgcgcttcaa taagaaagtt gttactagta
    14221 agaagtagga aatcatcatg ctaaggagac caaacaaagc aaagagtagg ttaaaattcc
    14281 gaacagcatc tctataagaa tccactttct cttgttgaat ggcttgaata gatgaaaatt
    14341 ttaaataatt tccatctgac aatttctcaa ctaactctgt aatctctttt tgatgttgaa
    14401 ccgtattttc aattttaatc ggattattta agccagttgt tgacagggag gctttctcat
    14461 cccacatcat atcagaatca ttgaccaagc taataattgg attggagaga ttttcctttc
    14521 gcttatcact atatgggaaa aatgaccaat ctccttcata ataggcaatc tcgacatcca
    14581 tctcctctat cgttcgtttt tgctgctctt catacttcat cgaatgaaag gcaattaact
    14641 tccccaagag ctgattttta tcttcttcac ctttcgtact tgctggcatc aaaataactt
    14701 ttttaatacc ggtatctggt agcttgaatc ccttgctctt tagaaaattg cgattggcat
    14761 agtaaacatc caccgtatct gttaactgat attgctgaat ctgttctgat tggacaaaat
    14821 tttttacagg aagactgcta ctctgcacat agcccgcctg cgttttttct accaaatcct
    14881 gataaaatcg atagaaataa tctgtagatt tccctgaccc tgctagctct tcttgccaca
    14941 gattatcatt gagtttgaag gtttctaagg tcaggtaatt accttgactt acccactgtt
    15001 gctgataagc aagttctttg ttttcttgtt ctaaacttct gcccacccca atcagtaagg
    15061 ccgtcagtaa aatagttgtc cctattttca tcacataatt gaagataaga ccaaatttga
    15121 aagatgaaaa acctttcagc agagagctga ttgtcatttt ttggattaag aggtaagtca
    15181 accaactgat aaagagataa agctgcaaca gcaaaaaatg agacaaccac agcataggaa
    15241 acaaatcttt tggcttataa tcaagcaaga aaaacacgcc tagattgatc acaagagccc
    15301 cacctaggag gaggtaaagg ttgcctttta caacatcagc taaaacagcc ctatcttgaa
    15361 aaccaagtaa tttttgtacc ccaactcttt tcatctccat catcggttga tacactgtca
    15421 ctaacacaag aagcaaaata gccaagacaa aaacaatggc agataaaagc aaatctcgat
    15481 ttatgacttc cactgcactt ttgtaggtcg gctctagcaa ggtagcctgg tctatcttga
    15541 aaaaatcgct ccatttctgt acaatcctat ccttgtccat ctcttgtgta gaagttatcg
    15601 tatagcgacc atttaaacta cgagatgtat ccttgatata ggtttgaaaa gtcataagct
    15661 gaataggttt ggcttttaga aaggtcggaa tcgtaccaag tttattggaa atttctttat
    15721 tactatagac tccttcacca tctgtggtaa aatcaagaga agaaatccca aactcttggt
    15781 aggggaaggt atctttatca aaaacaccag acttgaccac ctcatcacca ctgtctgttt
    15841 tgatgatgga gactttatac tcctttgata catcctcaaa aaatcgaaga acagacgctg
    15901 caggttcgtt aatatctttc aaatacaaat ccaaagaatc tacagtcttt cccatttctt
    15961 gaatccgaac cacttctcgt gtatagttta cattaaaaac aaaaaaagtg gtacacagaa
    16021 gcaggagtaa catacagaaa ttactgattt ttttcataaa agtgcctcca ctacagtttt
    16081 ccctctccaa ataggagagg gaagaatttt actcaaatcc atagaaatat tccattcctg
    16141 ttggcggaat cttggtgagg gaagctctag cccatgcctc aggttttgca taatccttag
    16201 aggttctacc cccatgtcta acagttgctg tatgatatcg agtagaatgt aagtaatcag
    16261 aatatccaaa agttcctgtc caacctactc catagttcca ttgaccaccc tcaacccata
    16321 ctgctaaagc atttgtagta gcaagtatac cacataccat taaagatgca acactaattt
    16381 tctcatgatt tatttctcct attatcgaga gctgttccgt aaaaacagct atagtaattt
    16441 atcaacaagt atcgtagtcc attggactca ccttccttct atctcatttc atttttaaca
    16501 acgaacttac tcttaaccgg gagaatggtg cgcttctgta tcaggtcctt gaacaaccag
    16561 agtagtatta agcacactct aactattact caagaatcag tccaataaac aatatggata
    16621 gcgctttcaa atttttaaac tcctatccca tccttttatc tatataataa gtgaaaatat
    16681 aataactgtc aagtaactga agtgaatttt ataaaaaaat tacaagccaa atttgtaaag
    16741 tttacactaa gccgctaggg caatcgtcta tcagaatatc cgtttatttg tcaataatcc
    16801 gagaaaatct tgcaacgctt agaagtctat aaaaactatc aacatttata tgacttgcga
    16861 atagcaatcc tgctaaacct ttccacactc tatctataca atcaagataa aaacatgtgt
    16921 aagcaaatct gctacacttt actggaggac gccaagaata agaaaagcta cgataggctg
    16981 gctatctgct atgtccctat tgggatttgt agggatgatg cgaaacttat ccaaaaaggt
    17041 ttctcactcc tagagctaac cgaggaaact tctatgctgt ctcatctcaa aaaagaagta
    17101 gagatctatt accaagcgaa ggaaagataa aaaagccgag ggatttcctc gactctttac
    17161 atattatttg ttcgttagtt cttaatacca gccattgtta agccagaagt ttttagcagc
    17221 tgtccatgaa ccgtaacgtc ctgcaacgta ggcatctgct acacgttctt ggttttcagc
    17281 tgagtagtca ccgttcaggt atgaatctgt taattggtaa cgtccgatat aacgtccatt
    17341 tgtagctgta tagctaccac ctgattcttt ttgagcgatc cattctttgg cttctgcttc
    17401 agatccgctt acagttgaaa caactgtttc acttactact ggagtttctg ccactggagc
    17461 tgaaacagtt tcatcttgag cggctggtgc cgcataagta gctggcgctg gtgttgcaac
    17521 aggcgctaca gggccatcga taaccaactt ttgatcaaca taaatcaaat gaatgttatc
    17581 aatgtggttg ttttctgcca atttttcaac tgttgtgttg tgagtttcag cgatttctga
    17641 aagtgtatca ccttctttaa cagtgtaagt tgatgattct tgagcagata caaatgatgg
    17701 agcaaatact gcaaacaagg cagctactcc tgcaagagtt gctttaatct ttttagttat
    17761 tgatttcata ttcgaaaatt ctccttcttt ctatagttct atcataccct ttaaatatta
    17821 ccgtttcttg acacttttat gtagaaatat tacaaaatta ttttttattt ccctaaataa
    17881 ggtgtttttt gtcataaaag atactatttt tatgctattt gaggtattag aaaggttttc
    17941 atccacaatt aaagccaagc ccctcattct ttgatataat agagataaga atttttataa
    18001 ggggaaactg atgaaatcac ttcgttttca atctgtcttt gatatcatcg gaccagttat
    18061 gattggccca tctagtagcc ataccgctgg tgctgttcgt attgggaaga ttgtctcttc
    18121 catttttgat gatactccga cagaagttga attccaactt tttaactcat ttgccaagac
    18181 ctatcgtggt cacggaacag acctagccct tgttgcaggt attttaggaa tggatacaga
    18241 tgatcctgaa attccaaata gtctggaaat tgcccacaag cgtggtatca agattgtctg
    18301 gaccattcag aaagacagca atgcccctca ccctaacacc actaaaatta ctgttaaaaa
    18361 tgcccacaag accatcagcg tgactggtat ttctatcggt ggaggaaata ttcaggtaac
    18421 cgaactcaat ggttttgccg tctctctcaa tatgaataca ccgactatca tcatcgttca
    18481 tcaagatatt ccaggtatga ttgcccttgt tacagaggcg ctttcccgct atggtatcaa
    18541 tatcgcccag atgaatgtca ctcgtgaaaa agctggtgaa aaagccatta tgattatcga
    18601 agttgacagt cgcaactgtg atgaggctat cgaagaaatt cgaaaaatcc ctcatctcca
    18661 caatgtcaat ttctttaaat aggaggaagc atgttttatt ctatcaaaga attggtcgag
    18721 caagcagatc tggactttca aggaaatgtc gcagaactca tgattacaac agagtttgaa
    18781 ttgaccggtc gcgaacgtga agaagtcttc cttctcatgg aacgcaatct ggaagttatg
    18841 aaagcctctg tccaacttgg cctcaatgaa aataaatctc gtagtggcct gacaggtgga
    18901 gatgctgcca aattggatca ctacatcgaa aacggaaaaa ctctgtcaga ttatacgatt
    18961 ctctcggctg cccgaaatgc catcgcagtc aatgaacaca atgccaaaat gggcttggtc
    19021 tgtgccactc caaccgctgg aagtgctggc tgtctgccat ccgttctcac tgctgctatt
    19081 gaaaaattag acctcagcca cgagcaacaa ttggatttcc tctttgctgc tggtgccttt
    19141 ggactagtca tcgcaaacaa tgcctccatc tcaggtgctg agggtgggtg tcaagctgaa
    19201 gttggttcag cctctgctat gagtgctgcc gccttgactc tggctgcagg tggaacacct
    19261 tatcaggcca gtcaagctat tgcctttgtc attaaaaata tgctaggcct catctgtgac
    19321 cctgttgcag gtttggtcga agttccctgt gtcaaacgta atgccatggg agctagcttt
    19381 gctttcatcg cagcagacat ggccttggca ggtatcgaat ctaaaatccc tgtggatgaa
    19441 gtgatcgatg ccatgtacca agtaggagca agcatgccaa ctgcctttcg tgaaacagct
    19501 gaaggtggac tcgctaccac ccctactggt cgtcgcctcc aaaaagagat tttcggagaa
    19561 taagcttatc aaataggaga aaccatgacc tctatcacag cgattttttt cgatttggat
    19621 ggaaccctcg ttgatagttc tatcgggatt cacaatgcct ttacctatac ctttaaagag
    19681 ctgggggtgc ctagccctga tgccaaaact attcgtggtt ttatgggacc acctctcgaa
    19741 agtagttttg cgacctgcct gtccaaagac caaatttctg aagccatgca gatatatcgt
    19801 tcttactata aggcaaaagg catctatgaa gctcaactct ttcctcagat tatagacttg
    19861 cttgaggagt tatcgagcag ttatccactc tacatcacca cgacaaagaa tacatctact
    19921 gctcaagaca tggccaaaaa cttggaaatc catcatttct ttgatggtat ttatggttct
    19981 agccctgaag caccccataa ggcagatgtc attcaccaag ccttacagac acatcaacta
    20041 gcaccagaac aagccatcat catcggagat accaagtttg atatgctggg agctcgagaa
    20101 acaggtattc agaaattggc cgtcacttgg ggatttggag agcaagcaga tctactaaac
    20161 tatcaacctg attatatcgc tcacaaaccc ttagaagttt tggcgtattt tcaatagcat
    20221 agactgggta acaactccat ttcagaagaa aatgaagtaa tactcaatga aaatcaaaga
    20281 gcaaactagg aaactagctg cgggctgctc aaaacactgt tttaagattg tagatggaac
    20341 tgacgaagtc agctcaaaac actgttttaa ggttgtggat ggaactgacg aagtcagctc
    20401 aaaacactgt tttgaggttg cagatagaac tgacgaagtc agctcaaaac actgttttaa
    20461 ggttgtagat ggaactgacg aagtcagtaa ccatatacgg caaggcgacg ttgacgtgat
    20521 ttgaagagat tttcgaagag tataagtctc tacataataa aacgcatatt accaaggttg
    20581 tttaacttga taatatgcgt ttttcttttt tattcaatgt gggttgtttg attagcaaag
    20641 gcgataatag cttgcttcaa ctcatctcca ctgagagtgc ggaactctcc aatcttttga
    20701 ttgatggatt ctaaaggcat gacattaacc ttaccaacga aaatcttatc cataacttga
    20761 ttgtcaacga gttcggttga taccaagagt tcttcgtaga gtttttcacc tgggcggatt
    20821 ccaacttcaa cgattggaat ttcactctca gtgtggccac ttagaagcac catcttcttg
    20881 gccaagtcat aaatcttgac tggtttgccc atatcaagga taaagacttc cccatctttg
    20941 gcataagcac cagcatggat aaccagacga ctagcttctg gaatggtcat aaagtaacgg
    21001 gtcatgcgga agtctgtcac cgttacaggc ccaccttcag caatctgacg ttcaaagact
    21061 ggaatgacac taccacggct accaagaaca ttcccaaaac gaactgcaca gtaggttgat
    21121 tggctacgtt ggttaaagcc agtgacaatc aactccgcca cgcgcttggt tgctcccata
    21181 acatttggtg gattaactgc cttatctgtc gaaatcataa ccatcttagg caccttggct
    21241 tcatcaacgg ctctagcaac attgtaagtt ccacggatat tgtttttgaa ggcttctttt
    21301 ggattgcgct ccatcatagg aacatgcttg tgggctgccg catgataaac aatagcaggt
    21361 ttgtactgct caaagacttg caacaaacga tcatagtctt gaatgtccgc aatcacaggt
    21421 acataatcaa tcccttggaa cttacgaatc aattcatgat aaacaaggta gattgagttt
    21481 tccccatgac cgagcaagac aatgcgttca ggattgaagc gactaacttg acgacagatt
    21541 tcagaaccga ttgaacctcc agctcctgtg actaagatgg tcttacctgt cagttctgca
    21601 cccagacgcg attcgtcaag acggatttcc tgacgaccca aaaggtccgt aatatcaatt
    21661 ttttggaagc cagtacctgc ttggtgaagg ccctgaacaa cagtttcaac cttaggcatc
    21721 ttgtaacatt tgacacccag cttattacac atctgcaaga tacgctcata ttctgacgga
    21781 tccagcgacg gaatcgcaac gatgacacgc tcgatttgat ggcgtttggc taattcaggc
    21841 agattgtcat aagagcccaa aacaggaata ccaccaagtt tttgaccctt tttcttagaa
    21901 tccttatcca aaataccgac cagttctaat tcactggttg gatgttggta actatccata
    21961 aagagagccc caccatcacc ggcaccaatc aagaaggtcc gacggtgttc tccatcacca
    22021 ctaccttttt tgcgtctgga gtagattaac tgccaagtaa tccgtggcaa taaaatcaag
    22081 aaggtactca acaagataaa gagaatgatg aaacggatgg agaagagtgg caagaaggca
    22141 taacagatac tatatgacaa gacactgcta gcagtcacac caaaaaagat tttcatgaaa
    22201 tccgtaatct tgctgtaacg actaatgctc gcgttcaacc cccaaaaacc aatcatcaat
    22261 tgatagaaca agaaggccaa actcgtatag ataatgtagt caacaggtgc tggattaatc
    22321 agcccataaa ataaaatata agatacaatt atggaaacca ccatactgaa aatatcaaat
    22381 attccccaga aaacctgctt ttgttgttta tttaaaattt ccaccagatc aatcacataa
    22441 tctgttagtt ttttattcat agaaatctac tcctccttaa aagagtttta ctatattgtt
    22501 attatagcat attttgattt atttggctta ttttatccaa ataaattatt gttcccttgt
    22561 actccttctt ccatttaaat cctctaatta aacctacaat cgtcccaagg ccataagcaa
    22621 agtgaatgga aaataaaaga aagggcatca caattagaaa tccattttta tgttttaata
    22681 aagtcagcaa agtgagtaat gacaaaagta gaaaataggc acctaatagt aaagttatga
    22741 atacgaatgt gatcggtaac aatgctagac taaacacaag actcaaaaca aataaacaag
    22801 gaacatagtg aaataatgat aaacacttaa actgaacatg acttgtcaag ccaatccaca
    22861 aaccatttga atacttttga tgcagcattt tcttgaatgt tggtcgaata tactgataag
    22921 atagaatact tgggctatag cggattttat aaccatgttc tcgaattcta taatgaatat
    22981 cattatcttc agttcggcca agttgctcat ttactaaacc aaccttctgg aaaacctctc
    23041 gtttatacat cccatgaaaa atagaagaaa catatctatc ctcggaacta tttcgataat
    23101 tggcaatgct actgccaaac atattttcct caacaagatg caaggtctct gcccattttc
    23161 cttttccttc gacaatcgtc ggtctaggcc ccccacagac aaattcacct tgttgaataa
    23221 tagccacatt gttaattaca aaactctcag taacttttga atgagcatca atttttaaaa
    23281 taaggtcccc tacagaatgt ttaactccca ggttaaaacc actagcttga tttttcttag
    23341 gattgttata caatctaatt gagttaaact ctgtatcttc ctttataaat tgctgaatga
    23401 tagctgtggt cccatctgtg gacatagcat ttataaatag aatttcaata tcctctttag
    23461 gataggtttg attttttaag tcttcaatta gaccaggcag atatttttct tcattgtatg
    23521 cactgattac aatggatacg agaagacttt caacattttg agtcactact actctcctga
    23581 atttttcctt ccaccattct atcataattt tcaagacttt cccattttta tcttgaaagc
    23641 cagaaacctt acttgacatt atagtgaaaa agccttaaaa taagctgtta ttaaaatcag
    23701 ctagaagagg tattatatga aaaagcaatc actctttttt gttccaggta ttatcctgat
    23761 tggtgtttcc ttgcgaactc cttttactgt tttacccatt attttgggaa atatttcgca
    23821 aggtctggag gtagaagtta gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt
    23881 taccctcttt tcaccatttt ctacccaact ggctcagaaa atcggcttgg agcatctctt
    23941 cacctacagc ctcttcttct tgaccatcgg ctcacttatt cgactaatca atctgcccct
    24001 gctctatcta ggaaccttga tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc
    24061 tagtcttatc caagccaatc aaccaaagaa aattggtttt ctgaccacct tatatgtaac
    24121 gtctatgggg attgcaacgg ctctggcttc ctatctagct gtgcccatta cacaagccag
    24181 ttcttggaaa ggacttatcc ttctcctcac gttactctgt ctagcaactt ttttggtctg
    24241 gctcccaaat caccgctata atcatagact agctccacaa accaaacaaa aaagtcaaat
    24301 aaaggtcatg cgtaataaac aggtttgggc aattattatc ttttcaggtt ttcaatcctt
    24361 gatcttttac accgtcatga cctggttacc taccatgtct atccatgcag gtctatccag
    24421 tcacgaagct ggcttgctga cttctatctt atctctgatt agcattcctt tttcaatgac
    24481 catcccaagc ctgacaacca gtttatctac tcgcaaccgt cagctcatgc tcactctggt
    24541 ttcactagct ggtgtggtcg gcatttccat gctctttttc ccaatcaata atttcattta
    24601 ctggcttgcc atccatctcc tcatcggaac cgcaaccagt gccctcttcc cttatctcat
    24661 ggtcaacttt tcactcaaga caagcgcccc tgaaaagaca gcccaattgt ccggcctatc
    24721 tcaaacagga ggctatatcc tagcagcctt tgggccaacc ctctttggtt acagttttga
    24781 cctgttccac tcttgggtac catctgtagc tgccctcttg ctcatcgata tcctgatgac
    24841 tgtggccctc tttacagtgg acagagcgga taagatcctt taaacttcta gttttagcta
    24901 gaagtttttt atatataaaa attttacaca tttctcttga cagggctttc ttttagatgt
    24961 acaatgtatg tgtagaaaaa ttatatataa aaatcttaca cattagaaaa ggaggtttcc
    25021 catgtacttt ccaacatcct ctgccttgat tgaatttctc atcttggctg tactggagca
    25081 gggtgattct tatggttatg agattagcca aaccattaag ctgatcgcta atatcaaaga
    25141 atccacactc tatcccattc tcaaaaaatt ggaaggcaat agctttctga caacctattc
    25201 tagagagttc caaggtcgca tgcgcaaata ctactccttg acaaacggtg gtatagagca
    25261 tctcttgacc ctaaaagatg aatgggcact ctatacagac accatcaatg gcatcataga
    25321 agggagtatc cgccatgaca agaactgaat acctgactca gctagaactc tatctcaaga
    25381 aactacctga agctgaccgt atcgaagcca tggactattt cagagagctc tttgacgatg
    25441 ctggagtcga aggagaagaa gaactcatcg ctagtttggg aactcccaaa gaagcggccc
    25501 acgaagttct atccaatctt ctcgataaaa aaatcaatga agcacccgct caaaaaaata
    25561 accgacaaat tttacatatc gccttgttag ccctccttgc agcacctatc ggcattcctc
    25621 tgggaatcgc catcctcgtg accctgttcg caattcttgt agccgctttg actgtcattc
    25681 tggctttctt tgcagtttcc atactgggta tcatcggcgg attcctattt ttagttgaaa
    25741 gtttcactgt cctcgcccaa gccaaatcag cctttatctt gatttttggt tctggtttac
    25801 tggctatcgg tgcttcttcg ctagttttac ttggcatttc ctatgcaact cgcttcttcg
    25861 gtctactcat tgttcgtctg gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc
    25921 atgcgtaaat ggacaaaagg atttctcatc tttggtgtgg tgactaccgt tatcggcttt
    25981 atcctgcttt ttgtaggtat ccaatctgac gggattaaga gcctactttc catgtccaaa
    26041 gaacctgtct atgatagccg tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta
    26101 gaaattactc tccaccaaca cacgctcacc atcacagact ctttcgatga tcaaatccac
    26161 atttcttacc atccatctct ttctgctcac catgatctta tcaccaatca gaacgataga
    26221 actctgagtc tcactgataa gaaactgtct gaaactccgt ttctctcttc tggaattggt
    26281 gggattcttc atatcgcaag tagctactct agtcgttttg aagaagttat tctccgacta
    26341 ccaaaaggga gaactctaaa agggatcaac atctcagcca atcgcggaca aaccaccatc
    26401 ataaatgcta gccttgaaaa tgcgaccctc aatacaaaca gctatatcct ccgaattgaa
    26461 ggaagtcgta tcaaaaacag taaactcaca acgcccaata tcgttaatat ctttgataca
    26521 gttcttacag atagtcagct agagtcaaca gagaatcact tccacgctga aaatatccaa
    26581 gtccatggca aggttgaact gactgccaaa gattatctca gaatcatcct agaccagaaa
    26641 gaaagccaac gaattaactg ggacatctca agcaactatg gttctatctt ccaattcaca
    26701 agagaaaagc ctgaatcaag aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc
    26761 gatgtcaagg atcaactcat tgcgagatct gatgataata ttgatctaat atccacacca
    26821 agcagacgtt gacaaaaacg cttacatttg ctactatgga aacatattta tctaactaaa
    26881 aaggaggttc taccatgaaa caagaatggt ttgaaagtaa tgattttgta aaaacaacaa
    26941 gcaagaacaa gcctgaagag caagctcaag aggttgcaga caaggctgaa gaaacgatag
    27001 ccaatctcga tacaccaatt ggaaaaaata ctcaagtaga ggaggaagtc tctcaagctg
    27061 aagtcgaact ggaaagccag caagaagaga aaattgaaac tcctgaaggc ggtgaagcga
    27121 gaacagaaat agaagaaaag aaggcatcta attctactga agaagagcca gacctttcta
    27181 aagaaacaga aaaagtcact atagctgaag agagccaaga agctcttcct cagcaaaaag
    27241 caaccacgaa agagccactt cttatcagta aatctttaaa aagtccttat atccccgacc
    27301 aagctccaaa atctagggat aaatggaaag agcaagtgct tgatttttgg tcttggctag
    27361 tagaagcgat caaatctcct acaagtaagt tggaaacaag tatcacacac agttacacag
    27421 cctttctctt gctcattctg ttttctgcat cttccttttt ctttagtatc tatcacatca
    27481 aacatgctta ctatggacat atagcaagca ttaacagtcg cttccctgag cagctagctc
    27541 ctttaactct tttttctatc atctctatcc tagtagcgac aacactcttc ttcttttcat
    27601 tcctcttggg tagtttcgtt gtgagacgat ttatccacca ggaaaaggac tggacgctag
    27661 acaaggttct ccaacaatat agtcaactct tggcaattcc aatcttcctc actgctattg
    27721 ctagtttctt tgctttcttt gatagcctac gatttacagc tctcttgtgt gtgattagca
    27781 ttggaatcat tctgcttgcc agtctccata tcattacaag accaagtcaa gcaagtgaaa
    27841 ccgactcctt ctatcaatta ttcttgtctg tccttgtgaa cggagttatt atcctcctct
    27901 tctttgtagc tgaagtggca ctgattggag attatcttcg tatcttggcc tttctttaaa
    27961 attcaatcct gtcatccttg gcaggatttt ttctatgtca aaaaagcaag tcgattgacc
    28021 tgcttctgct ttacttttct tgtgctaatg ttttaaaatc tttgtctaat atgggttgca
    28081 cttctatttg attggcgtct agttggtggt aaaaagatgg gggtaatacc tctaagaatt
    28141 ttgcatagtc caagcgagct atggattcat agtcttctgg tttagagccg tctcctgtga
    28201 tttgaaccaa gtcaatctcc cactggactt ccttatccac caattgctca atataggctg
    28261 caggaacaaa cggttctctc ggtaaaactg tcttgactcc ttgagctaaa tggtaaacgc
    28321 catgcacttt tccttctcca tcctgataga aggaaactct tgcaaagtag gcatctgtct
    28381 cttgaaccgc acgcacacgc gcttcaaact gagccaagcc atctgcctct aaaaagcttt
    28441 tcaagttctc acgactaaag aaaataggat taaaaattcc ttggcaaatc gtaaaacgag
    28501 ctacagggtc tgctagatag gcttgaatac ttgcttggaa ataagcttca aaatcaaaac
    28561 catctagccc ttcaatatca gtccctgtat aagcaagcaa agcatctaaa aatgacttga
    28621 taatctgcca gtctgtcttt gttagtaggt caggaagatc gacacggtaa gccttttgac
    28681 catcagcata actgacctta aagagaaatt gtgattgccc cactatcgca cactcaatat
    28741 actcgagacg attaagaggc tgacgaagat agactacatc atagctatgt gactccaaac
    28801 cgtctagcaa ggccaagatc gacttggcat tcaaaatctc ttgttctcct aaaatgctct
    28861 gtttatttgg aataaaaaat gtttttgcca taactggact cctttgaaat cgtttacata
    28921 cagtatacct tattttcctg aaagatacaa aaacaaactt tagatttttg agtacaaagc
    28981 atagaaaaac agcccctgag gactgtttga tcttatacag tagctgcctg atccaagctt
    29041 tcaccgatag cggctaggcg ctcaatcact tcagcttgtg tcaattcatt ttttgaaaca
    29101 tagcggttac gtgggtgaac acggcactcg tgtgagcatc cacgaaggta cttgtcttca
    29161 ttttcttctg atgtcaagat acgacggtta cagaagggat ttccacagtt gacataacgt
    29221 tcacatggtg ttccatcaaa ccagtctttc cctacgatgg ttgggttgac atggttgaca
    29281 tcaacggcaa tacgctcgtc aaagacgtac attttcccat cccaaagctc accttgaact
    29341 tctgggtctt taccgtaagt tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct
    29401 tcacggacca tccagcctga gaatttctca cagcgaacgc cacctgtaca gtaaaccacg
    29461 acacgcttgt ccatgaattt ttccttgtta tcacggaccc attgtggtaa ctcacggaag
    29521 ttgcgaatat ctgggcgaat agccccacgg aaatgtccta ggtcgtactc ataatcgtta
    29581 cgtgtgtcaa ggacaacggt atctttatca agaagcgctt ctttgaactc ttttggagac
    29641 aagtaagcac ctgttgtttc aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa
    29701 ccaaggtgga caatttcttt cttgtagcga acaaacatct tcttgaaggc ttgttcattt
    29761 tcttcgtcaa tcttgaacca gagttcttcc attcctggaa ggctgtgaac gtagtccatg
    29821 tatttttgag ttgtttcata gtcacctgaa actgttccgt taattccctc gtcagcgact
    29881 aggatacggc ctttaaggcc gattgattta cagaaagcca agtggtctgc agcaaattgc
    29941 tctgcatttt caattggagt ataaaggtag taaagtaaga cacgaatatc ttttgccata
    30001 agatttgttc tcttttctat tcttaaattt tctaaatttt ttatttatct acactagtat
    30061 acctgcttga gaaaacgaat gcaatttatt tgactggaaa ttgtagaggg ttctcgaaat
    30121 ttcctgaatg gttaaaataa ggacaagaga aaacatggat atctatatcc ttgtgccaaa
    30181 aaaaccactg ccctccccag accaacctga ggaaagcggt gattcttatt ttaggagtta
    30241 ggaatgaata cacgaaatca atttagctga ttattttttg tttttcaaga attcatcgta
    30301 ttgtttttgc atttcgttca atactttttc gtaggcacct tcagatttca atttttccat
    30361 caattctgga atcgctttat ctgggtctac agtaccagtg ttgatagctg tatcaaattg
    30421 ttgcattgtg ttagcaatag ctgagatttc agatttcaca ttgtcagtat tgaagataaa
    30481 tccaagcgct ggagattctt tagcttctgc caattctttc ttagaatttt cgatttgttg
    30541 gtctgtaacg ttttcgttga tgtaaaggat ccagttgtta ccagtgttcc atccacccat
    30601 gtgagtgttt cctttgtagc catcaagaac gcgaacacgg ttttctttac cttcaatttt
    30661 ttcccagttc ttgccttctg gaccgtaaac aagaccgttc aaaagttctg ggttcgtatt
    30721 caagaggttc aagatttcca ttgatttttc tttgttctta gagttgtttg agatgacaaa
    30781 gttagcaact tgtgttgttt ggtttttctt gatgaagtta gtgattggtt tgatttggat
    30841 atctttgttg gcaacacgtg aaagcaagct gttaccgtag tcagctggtc ctactgtttc
    30901 ttcacgaacg aaccaagtat cttgttgaag gtcaaatgaa gtgtcacttg ttgcgacgtc
    30961 ttttggaatg tagccagctt catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg
    31021 aggcacttcg taacggttta caactttagt agtatcgcct tcaaggtcaa taacgaatgg
    31081 aagcccgttt gctactgggt agtcaaagtt atcagatggg atgaaaactt taccaatagc
    31141 aaatggtact acgtctggag ctttttcttt gatttgtttc aagactggct caagagtttc
    31201 gtaagaagta acacctgaaa tatcgatacc atatttggca aggagagttc cgttgaaggc
    31261 aaagttttga gatgatgcta cgttggctgc aactggtaca gcgtaaatct taccatttac
    31321 agtattaccc ttgatataag ctggatcaag tgccttgtaa aggtctttac cttctttttt
    31381 gtacaattct gtcaagtcag cataagcacc tttttgagca tttacaatat agttatctgc
    31441 aaaggcgata tcatagtttt caccagatga tgtgataact gacattttct taccatagtc
    31501 accccagcca aggtattgga tatccaattt ggcaccaact ttttcttcga tgattttgtt
    31561 ggcatttgct aacaattcat ccaagttatc tggtttgtca ccgatttggt acattttgat
    31621 aacaggtttg tcacctgaat cagcagcttt tttgctgtta cctgtcaaat ttccacaagc
    31681 agcaagacct gcagccaaag cgactacact agcagatgca aaagcatatt ttttccagtt
    31741 tttcatgata aaaactcctt tttttatttt taaacttata aacaatgtaa tgatcttaac
    31801 ttcacgcaag ggaagtttgg aaacaagtgc tattctttca caccaccgat agtcaaacct
    31861 tttacaaagt agcgttggaa gaatggatac aaaattgcga ttggaagggt tgctaccaca
    31921 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    31981 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    32041 tacaagttgt cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    32101 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    32161 aaaatccggg cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    32221 gtcttcttga agaaggaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    32281 atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat ataacctggt
    32341 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    32401 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    32461 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    32521 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    32581 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    32641 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    32701 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    32761 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    32821 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    32881 tgctgtctga gtcaaaccat taaaaacata tacgtccaaa acgttggtta cattgtaaag
    32941 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    33001 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    33061 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    33121 tcccatgatc gtcgcatagt acatgacact gctatatcca aaacctttcc aaatacctag
    33181 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    33241 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    33301 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt ggaaaatctt
    33361 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    33421 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    33481 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    33541 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    33601 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    33661 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    33721 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    33781 tttgcaggtt aggttaaact cctaattata gaaaaaattc cacaaattat gtagcagatt
    33841 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    33901 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    33961 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    34021 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg cttcagtatg
    34081 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt cttgagagtt
    34141 ttcaaggaca tccttatctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc
    34201 tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat
    34261 atcacgtaaa ccttgctctg tcaaactatc atctgtaaga gctttcttag cctctgccaa
    34321 aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt
    34381 ttctaaggtt tgagtctgct tactaatact agactaaaat caaaaagcat tacataacag
    34441 tgatatgaaa tcaactaaag aagaaatcca aaccatcaaa acacttttaa aagactctcg
    34501 tacagctaaa tatcataaac gccttcaaat cgttctatag taaaatgaaa caagaacagg
    34561 acaaatcgat caggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact
    34621 attctagttt caatccatta tatttcgtct gatgggcaaa tcttataaag agattataga
    34681 gcttttatag tgatttgaaa taagatgtga acaactctat caggaaagtc aaattaattt
    34741 atagaaatat tttagcagcc aaggtgtact gttatagatt caatacact
//
LOCUS       DBERAE010000017        34663 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.17, whole genome shotgun sequence.
ACCESSION   DBERAE010000017 DBERAE010000000
VERSION     DBERAE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.17"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(186..1341)
                     /locus_tag="ACL70N_001022"
                     /pseudo
     CDS             complement(186..1341)
                     /locus_tag="ACL70N_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            1323..1630
                     /locus_tag="ACL70N_001023"
                     /pseudo
     CDS             1323..1630
                     /locus_tag="ACL70N_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1653..2003)
                     /gene="tnpB"
                     /locus_tag="ACL70N_001024"
     CDS             complement(1653..2003)
                     /gene="tnpB"
                     /locus_tag="ACL70N_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0589838.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1984..2169)
                     /locus_tag="ACL70N_001025"
     CDS             complement(1984..2169)
                     /locus_tag="ACL70N_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589839.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2473..4035)
                     /gene="guaA"
                     /locus_tag="ACL70N_001026"
     CDS             complement(2473..4035)
                     /gene="guaA"
                     /locus_tag="ACL70N_001026"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGS0589840.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4177..4875
                     /locus_tag="ACL70N_001027"
     CDS             4177..4875
                     /locus_tag="ACL70N_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0589841.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4918..5814)
                     /locus_tag="ACL70N_001028"
     CDS             complement(4918..5814)
                     /locus_tag="ACL70N_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0589842.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILHIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5823..6758)
                     /locus_tag="ACL70N_001029"
     CDS             complement(5823..6758)
                     /locus_tag="ACL70N_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGS0589843.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARFLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6755..7480)
                     /locus_tag="ACL70N_001030"
     CDS             complement(6755..7480)
                     /locus_tag="ACL70N_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGS0589844.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7564..8199)
                     /locus_tag="ACL70N_001031"
     CDS             complement(7564..8199)
                     /locus_tag="ACL70N_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGS0589845.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8201..9028)
                     /locus_tag="ACL70N_001032"
     CDS             complement(8201..9028)
                     /locus_tag="ACL70N_001032"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0589846.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9050..9385)
                     /locus_tag="ACL70N_001033"
     CDS             complement(9050..9385)
                     /locus_tag="ACL70N_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGS0589847.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9386..9976)
                     /locus_tag="ACL70N_001034"
     CDS             complement(9386..9976)
                     /locus_tag="ACL70N_001034"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGS0589848.1"
                     /translation="MGDFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNH
                     ILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNG
                     IEQYISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLELTEEQKALY
                     HKMIDWGADIIFGGHPHVVEPSETVEKDGDKKLIIY"
     gene            complement(9992..10114)
                     /locus_tag="ACL70N_001035"
     CDS             complement(9992..10114)
                     /locus_tag="ACL70N_001035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589849.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQGD"
     gene            10627..11238
                     /gene="def"
                     /locus_tag="ACL70N_001036"
     CDS             10627..11238
                     /gene="def"
                     /locus_tag="ACL70N_001036"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS0589850.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11283..12011
                     /gene="rlmB"
                     /locus_tag="ACL70N_001037"
     CDS             11283..12011
                     /gene="rlmB"
                     /locus_tag="ACL70N_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGS0589851.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(12050..12961)
                     /gene="trxB"
                     /locus_tag="ACL70N_001038"
     CDS             complement(12050..12961)
                     /gene="trxB"
                     /locus_tag="ACL70N_001038"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGS0589852.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13027..13251)
                     /locus_tag="ACL70N_001039"
     CDS             complement(13027..13251)
                     /locus_tag="ACL70N_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGS0589853.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAGARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13329..14072)
                     /locus_tag="ACL70N_001040"
     CDS             complement(13329..14072)
                     /locus_tag="ACL70N_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0589854.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14072..14872)
                     /locus_tag="ACL70N_001041"
     CDS             complement(14072..14872)
                     /locus_tag="ACL70N_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0589855.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15030..15386)
                     /locus_tag="ACL70N_001042"
     CDS             complement(15030..15386)
                     /locus_tag="ACL70N_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS0589856.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLSVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15399..15911)
                     /locus_tag="ACL70N_001043"
     CDS             complement(15399..15911)
                     /locus_tag="ACL70N_001043"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGS0589857.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15911..16405)
                     /locus_tag="ACL70N_001044"
     CDS             complement(15911..16405)
                     /locus_tag="ACL70N_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS0589858.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16540..16986
                     /locus_tag="ACL70N_001045"
     CDS             16540..16986
                     /locus_tag="ACL70N_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGS0589859.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMINNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16983..17630
                     /locus_tag="ACL70N_001046"
     CDS             16983..17630
                     /locus_tag="ACL70N_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGS0589860.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKNVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17651..18232)
                     /gene="pdxT"
                     /locus_tag="ACL70N_001047"
     CDS             complement(17651..18232)
                     /gene="pdxT"
                     /locus_tag="ACL70N_001047"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGS0589861.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLLIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18233..19108)
                     /gene="pdxS"
                     /locus_tag="ACL70N_001048"
     CDS             complement(18233..19108)
                     /gene="pdxS"
                     /locus_tag="ACL70N_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGS0589862.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19260..20639)
                     /gene="nox"
                     /locus_tag="ACL70N_001049"
     CDS             complement(19260..20639)
                     /gene="nox"
                     /locus_tag="ACL70N_001049"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGS0589863.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20933..21856
                     /locus_tag="ACL70N_001050"
     CDS             20933..21856
                     /locus_tag="ACL70N_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGS0589864.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     IFWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21916..22521
                     /locus_tag="ACL70N_001051"
     CDS             21916..22521
                     /locus_tag="ACL70N_001051"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS0589865.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22540..23784
                     /locus_tag="ACL70N_001052"
     CDS             22540..23784
                     /locus_tag="ACL70N_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGS0589866.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGCHGGDADATAGASY"
     gene            complement(23900..24157)
                     /locus_tag="ACL70N_001053"
     CDS             complement(23900..24157)
                     /locus_tag="ACL70N_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGS0589867.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24199..26235)
                     /gene="glyS"
                     /locus_tag="ACL70N_001054"
     CDS             complement(24199..26235)
                     /gene="glyS"
                     /locus_tag="ACL70N_001054"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGS0589868.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26447..27364)
                     /gene="glyQ"
                     /locus_tag="ACL70N_001055"
     CDS             complement(26447..27364)
                     /gene="glyQ"
                     /locus_tag="ACL70N_001055"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGS0589869.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27732..28493)
                     /locus_tag="ACL70N_001056"
     CDS             complement(27732..28493)
                     /locus_tag="ACL70N_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS0589870.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFFTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKIFPLLDWFVQQKLIEKEI"
     gene            complement(28766..29608)
                     /locus_tag="ACL70N_001057"
     CDS             complement(28766..29608)
                     /locus_tag="ACL70N_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGS0589871.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29722..31113)
                     /gene="pgdA"
                     /locus_tag="ACL70N_001058"
     CDS             complement(29722..31113)
                     /gene="pgdA"
                     /locus_tag="ACL70N_001058"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGS0589872.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYSSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31351..31719)
                     /locus_tag="ACL70N_001059"
                     /pseudo
     CDS             complement(31351..31719)
                     /locus_tag="ACL70N_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31958..32935
                     /locus_tag="ACL70N_001060"
     CDS             31958..32935
                     /locus_tag="ACL70N_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0589873.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYSKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGTLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQDPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32932..34014
                     /locus_tag="ACL70N_001061"
     CDS             32932..34014
                     /locus_tag="ACL70N_001061"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0589874.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTLIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34078..34663)
                     /locus_tag="ACL70N_001062"
                     /pseudo
     CDS             complement(34078..34663)
                     /locus_tag="ACL70N_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10287 a         7746 c         6272 g        10358 t
ORIGIN      
        1 tagtctctat acctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa
       61 cctgaatctt cctgttcctt atgaaccacc tggaagaaaa gcgtcgttaa tgatgcatta
      121 aagaacagtc gagatgaaaa aatcgtgtga cgcaccaagg gaggagtctg cccttttgag
      181 gaaatctagc gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga
      241 ggaagaaagt ggctcatgag gtcaggggtt ttgtaagtta catctagttg agagaggtat
      301 gaatgatttg ggataatagc tcttgcttta gctccttcaa aactttgaga aaaaaccacc
      361 ctcgcttttt taaactgagc ttaggctaaa agagtccagt ggactctttt actccgtccc
      421 ataaccaatg atttaatggc gcgttcagct agattattgg aaaggaccag atgtccgtct
      481 tttaaaatgg tcttaaaggt ttcttcatac ttgaggctgt attcaattgc ccttcctggt
      541 tttgaacctg ctaaaactga ctgacggcgg caccaagcaa agaagtcttc cattaagggc
      601 tggacgtttc tgtagtcgtt catcagctgg caaagcctcc cagtctcttt ccaaggcaaa
      661 taactggtca cgataggcta aacctttagc tcctaaggat gatttatctg cttgcttggg
      721 ggtcgcttca aaaaatttcc ttctcacatg cgcccaacat ccaacaagtt cagcttcttc
      781 cagttgacga taagcttcta gcggttcgca gtttaccaag cttagcgtcg ccttgctcct
      841 aaaccttaga ctgctatcgc ataggcagaa ctagaggact aaagttctaa gttactgccg
      901 caacatatca caatgcatat agccagaata atttcctagg aattcttgca ctaccgaacc
      961 actccgacgc tgatcatggt ggtacagcgt aatcccttgt ttctcagctt tcccagacaa
     1021 aaaagtccaa tagtaagtca gctgactatc actttctaag acccgataag aggtttcatc
     1081 tgcatgaaga agagcttgtt ctaacaactt ttctcgtaaa aggttataaa ggggctccaa
     1141 atagtattga ctcgtcttga tatgccaatt agagatttcc ttacgtgtga ttggtaaacc
     1201 catcctagcc caatcttctt cttggcgata attgggtacc ttcagattaa acttctgatg
     1261 gatggtgtga gcgataatag aagctgagcc aaggctatgc gccaaagggg ctttaggaat
     1321 aggagctttc acaagcttat ccagatgatt atcttttact cgttatggac aatgctatat
     1381 ggcataaatc aagtacctta aagattccga ctaatattgg ctttgcattt attcctccat
     1441 acacaccaga gatgaaccca ttgaacaagt gtggaaagag attcgtaaac gtggatttaa
     1501 gaataaagcc tttcaaactt tggaagatgt catgaatcaa cttcaagatg ttatacaagg
     1561 actggagaag gaggtgataa agtccatcgt taatcggaga tggactagaa tgctttttga
     1621 aagcagatga gtataaaaag aaagtcctca tttcaataga aatcacgact ttctgataaa
     1681 tttattttgg gagtgataga aaagcccttc ataagccaat ctacttgttc aggtgtgaga
     1741 gctttgacat ccttttctgt actgggccaa gtcagtctgc cgttctcaaa gcgtttatat
     1801 agtagccaaa atccttgacc atcccagtaa agggctttaa agcggtcttt acgtccacca
     1861 caaaagagaa aaacttgacc ggagaaagga tccaattcaa agtgggtttt aaccagataa
     1921 gccagtgaat cgattccttg tctcatatca gtcttcccac acacgagata gacctgccct
     1981 aggctagata gatgaattgt catagagcaa caccttatcc aaaagctgtt ctaccatttc
     2041 gagattgaga gattgaaaaa aacttacttc aagcttgcca atacgaattt taagcagaat
     2101 atcatttctc tttttagaat caaaaggacg agattgtgga atctctacag gaacaatagg
     2161 ttgtggcatt aaaatatcct ccaatagttt tactttacta atagtataca ggaggaactc
     2221 catgaatgat agataccttg ttatgacgcg cttactatat tagaaagttg gctctctaat
     2281 taaattaatt ctcattatat atatcaaaag accgcagttt gaaaactacg gtctaatttt
     2341 ttgtccaaat gtaaatcact tggaactatt attcaattta ttctttttag taaatgttcc
     2401 cgttttaatc ccagttacag tttttaatcc tctgtaaccg ttgattttac aaagctttta
     2461 atttttttgc gattactccc actcaactgt tgcaggtggt ttacttgtaa tatcgtagac
     2521 gatacggtta acatgatcca cttcatttac gatacgtact gagatttttt gaagtacttc
     2581 ccatggaatt ttggcaaaat cagcagtcat accatcgata gaagtgatag cacggattgc
     2641 aatcgtgtag tcatacgtac gaccgtcacc cataacaccg actgaacgaa cgcctgtgtt
     2701 aacagtgaag tattgccaaa tatcgcggtc aagtccagct ttagcgattt cttcacgaag
     2761 aatagcgtct gattcacgaa cggtttcaag tttctcttca gtgatttcac ccatgacacg
     2821 gatagcaagt cctggtcctg ggaatggttg gcgccatacg atatggtctg gcataccaag
     2881 ctctgtacca agagcacgaa cttcatcctt gtaaagagta ttgagtggtt caatcaattc
     2941 aaactgcata tcttctggaa gaccacccac gttgtggtgt gacttgatag tttgagctgt
     3001 atccgtacca gactcgataa catctgtata taaagtacct tgagcaagga atttcacatc
     3061 tttgagcttg cttgcttcgt catcgaatac atagacaaac tcgttaccaa tgattttacg
     3121 tttttgttca ggatcagaaa cgccagcaag tttgtcaagg aaacgtttag cagcgtctgc
     3181 tttgacgata ttcaaaccaa acttaccacc gagcatgtcc ataacttgat cagcttcgcc
     3241 tttacgaaga agaccgtggt ctacgaagat acagatcaat tgatcgccaa tcgctttttg
     3301 gagaagaacc ccaacgacag atgagtcaac accacctgat agaccaagaa ggacacgttt
     3361 atcaccgacg gtttcacgaa tttttttgat ctgcatgtca atgaaattat ccattgacca
     3421 gtcaccttta gccttacaaa tgttaagggc aaagttacga aggatatcat ttccgtatac
     3481 agaatgacga acttctgggt ggaattggat accgtaaatg tgtttatctg ggttttcgat
     3541 ggctgcgtat gggcagtcag ctgatgtacc tgtacgaaca aagtcagcag gaatctcagt
     3601 aaccgcatca ccatggctca tcaaaacagt ctgttcatca ggtgttgatt caaaaagcgc
     3661 tgatggtgtg tgagttaggg ttgattgacc gtattcacga tttccagcat cacctgcagg
     3721 aacaactttt cctccaagtt tatgggtcaa taactgcata ccataacaga ttcccaaaat
     3781 tggaattccg agttcgaaga tttctgggtc aatatcaaat gaaccatctt catatacaga
     3841 atttggacca cctgatagaa taattcctac aggattgact tcacgaactt cagcagctga
     3901 aattttatgg ctttttagtt ctgaaaaaac accaatctca cggatacggc gtgaaatcag
     3961 ctggttgtac tggctaccat agtccaatac gatgattttt tctacatctt gcaaatcagt
     4021 tgaaatgttg ctcatctttt tcctttctca aaagaaatat cttttctcaa tattctatca
     4081 caaataaggg cgaattacca actaaacaag gcgaagtttg actttttcta gtttattggg
     4141 gtacaataga gaaaagatag aaatgaagtg aaaaatatgc tacctgctta tatgaaaatc
     4201 catgatcaga taaaaaagga tattgacgag caccgttggg ctattggtga gaggcttccc
     4261 agtgaaagag atttagctga gcagtttgcg gtcagtcgca tgaccctccg ccaagccgta
     4321 tctctattag tcgaagaagg cgtcttagag cgccgtgtag gaagcggcac ctttgtttcc
     4381 agtactcgag tacaagaaaa gatgcgaggg acaaccagtt ttactgaaat tgtcaaatcc
     4441 caaggtaaag ttccctctag ccagctcatt tcctacaaaa aaaccattcc caatgagcaa
     4501 gaagttgcca agctaggaat ttttccaacg gacaatatta tccgaatgga gcgggtccgc
     4561 tatgccgacc aagttcccct agtttatgaa gttgcttcta ttcctgaaaa attcattaag
     4621 gactttaaaa aagaagaaat caccagtcat ttcttccaaa ccttgcaaaa acatggctat
     4681 cgtatcggta aatcccaaca gaccatctat gctcgccttg ctaaagaaaa gattgcccac
     4741 tatttggaag ttgaaaaagg acatgctatt cttggattga cccagatttc ctacctagaa
     4801 gatggtactg cttttgaata cgtaaaaagt caatatgtag gcgaacgctt tgaattttat
     4861 cttgaaaata attagattac cacgcaaaaa ctctctgtca cggacaaaga gtctttttta
     4921 tttttctaag aataaatctt tcaaagaaat caaagttaca gcaaacaata tcattgccat
     4981 accaagaaaa tcaatgggat aaaattgttc attcattatt aagaaggcaa agaaaatcgc
     5041 cgatattggc tcaattgaag ccaacaagct tgacttgacc ggtcctatca gactggctcc
     5101 tttaaggaaa gctgtatagg caaagacagt cccgataagg ataatgcctg caaacgcaag
     5161 gagaaaatca agactagtcg ggatatcggc ctgtagaacc cctgtaaaag gaagggcgac
     5221 caaacctgct atgaccattc ccacaccaat gaccaagctg ctcccccact ttttaatcaa
     5281 ggctatgtgt aaaatgatat acaaagcata agtcaaggca gaaaagagac cccagaacag
     5341 accagcaggt gtcatggata actggtccaa ctgcccatgt gttgcgatca ggaaggttcc
     5401 tccgatggcg aatatgatgg aaactatctc tcccagtgtc ggtgccaccc tatccttgat
     5461 acagctataa attaaaattc cgacaggaca aacatactga agcaccgtcg ctgttcccgc
     5521 attggtctcc tgaatagcag acagataggc gaattggttg agaaaaagac caatcagagc
     5581 aaaaataaga agagacagca aactctttct atcctttaaa aagaccagta ttttatcctt
     5641 tgcagtagca taagccaaga gcatgagaat tccaccagcg attaaaagac gcaagttagt
     5701 caagaccaga gccgaaattc cgtgtgccat taggtattgg ccactcgttc ctgacaaccc
     5761 ccaagcaata ccagccacaa ctgttagtaa agtccctttt aaactatttg acatgtctct
     5821 ccttactctt ctttgcgaat caagttcatc acttgattgc ggtctaatat ccattgagct
     5881 ctctcgtcct tttcataggt acgattcgat aggaaaatag tggcttcttg cttctgacga
     5941 ttccacatga taaaggtacc tgtatagccc gtatggtcta gccaatctcc ttccaaattc
     6001 catgctaaag aacgttcctt gtcatccaaa ggagaaaaat tttgatttaa gtctcttgca
     6061 aaatcatctg ctaaatagtg ttctaaaaag atttgtaaat cctttatagt cgaaaataaa
     6121 ccagcactcc cagcatgtct acccaggaaa cgagccttgg gatcatgcac tatgcctgcc
     6181 tctacacctc taactgttgg aacagcaagc tcaactggcc caaacttagt ttccgtcatt
     6241 ccccaaggtt tccagacttg atcctttaaa atcacatcca aatcttgatt aaaaattctt
     6301 tccaaaataa agcccaacag caaaaaatgg acatccgaat aaagaaaggc tggctgactt
     6361 cgtctgttga gatgaaacat cgcttccttt aattcagggg ctgttaaaag atcacgatta
     6421 ggaataaaag gatcaaggtc tgttgcatga gtcaagagct ggcgaatagt gatgtctgga
     6481 taatcactct caggtaaaaa atctattacc agtctatcaa tatctaattg acctatttcc
     6541 cacaagaagg tacaaactgt gccaacccca acaaccttgc tgacactagc taggtcataa
     6601 actagtcctg cctcagtctg caagccatgc tctggggcac tctggcctaa atagaactct
     6661 gtccattgat tgtccttaaa atacgcaaaa gaggctccgg gataaattcc tgcctcgatt
     6721 tgttcttcta tttttttaat aatcttggtc cacttcatac ttcttcaaac cacaattcaa
     6781 cattatttct atctttacca aggaagaatt tttcagactt aggaataaaa tattcagtag
     6841 actcaaactt ctggcgaaga cttgctatgt ctaattcatt gaccaagaac ttgagcatag
     6901 ataagtccca ggtaaccgta ttgtccacag tcaaatcctg cccctgagct ggaataaaat
     6961 caagggatgc cccaatttca gatgattcca agaaactttc gatatcagtt gggagatgta
     7021 attccataga aatctcaaat ttacttaaag aaattgatgc caaatctgtt tgaaattcag
     7081 gcttttctcc tacttctact agacttgctc tgtcatcttc cgcatgaatc aaaatcaaat
     7141 catcttctgg tgagaaaatt tcaaaagcgt agccattttg acctttatat aatcgatgaa
     7201 tcgaatctgt tttagataag attccttcaa tttctaaggg attttccacc ttgacaatca
     7261 atctagctag tttttttctt ccctctacct tacgagtacg catactggga gcttcttcta
     7321 aaaccagctt ttcaagaccc gtttggtcac ctagtgacag aaaggccgat tcttctaaca
     7381 gggccttcat tccaagggtt tcaatataaa atgtttcatt taattttcta ttattagctt
     7441 ttaaagtagg aataatccgt acaatctgat ttacattcat aaattcctcc gtcacttttt
     7501 attttaaagg attttagaat tttttacaag atattatgct caaatttaac attatttagc
     7561 tatttagtaa agatagtctt tcaaggcttt tgacaaagcc tgataaccag caatactgag
     7621 gtgcagtcca tcagttgtat attctttttt gagttggcct gcttggtctg tcaaacaatc
     7681 aaatactggc acaaattcca cctgcatata ggcagatgca agctcttgat aggcttgatt
     7741 ccaattctga attttttcat tcgagcggat atagactgcc tgctggtact tctctccctc
     7801 attgacaggc aaaatggaaa gcaatttaat ctctgtcaat ggataatcgc gagcaacgga
     7861 ttgaatgata gcttcgagat tattgagagc ctcattcaca ggaacatcct ttccgatatc
     7921 atttgtccca atcagaagaa aaattttatc tactgctcca ccatatagat gagcatcaag
     7981 gttctctagt aacagtcctg tctgatagcc acgaattcct cgattgacaa tcgtctttga
     8041 agtcccaaat agctcctgta gaggataata ctcgacaatg gaatccccaa taaaaagaat
     8101 gtttggttct acaacagaaa tgtgatttag gtgacgatat ttggtttgaa ttttttcttg
     8161 ttcctttagg agccaatttt ctaataactg tactgccact tcattctcct ttttctaacc
     8221 agttttccaa gacttgataa actcctcctt ggctgttggc tggtgctaga gcagtcgcca
     8281 cagctttggc tttctcatca gcattttcca tcgcataggc aattccagcc atttcaagca
     8341 tttcaacatc attttcacta tcaccaaaag ccatgatttc ttgggatttc aagtcccagc
     8401 gcttgagtaa ttcctccaag ccccatgctt tatgaatccc agcttggagg atatcaatgc
     8461 aaccatagcc actggataca gctcggacac ggccatcaaa gagagcattg atttcttcca
     8521 aaaccgaact caaacgttcc tcaccaacaa ccatgctcat cttgagcaca ccaccaaaga
     8581 ggtcagatgt taattcatcc acaaattgca tccgttggta gaatttttca atcatttctg
     8641 gagtcataaa actttcaaga tctgtaaaaa tcgtaccttc cttgacaaaa tcacccttca
     8701 tccccgttac aacaaactgg tcctgacacg ctcgaccctt gaaatgagcc aaagccttgt
     8761 tgacaatggc gtcatcccat gtctgagcct gaatcaattc attgttttca aaaatacgag
     8821 cgccattagc aacaaccaga accactcgat ccaccaaggg actcagtagt tgtctcatgc
     8881 ggtgaatttc attgcccgtc gcaatgacaa aacgaatgcc cctttgatcc aactgatcta
     8941 aaatcttttc caatcgtggg agatcaagct gacctctagc atccagcaag gtcccatcca
     9001 tatctgtcgc aattacctta atcatcattt actttcctct ggattcaagc taataccact
     9061 tcaatcccac atgttcattc atttctttat aggctgtatc aattcgttcc ttagtcgctt
     9121 catctaactg gtcacgatga ctgccatcct ctataaaatc ttccaaaata taagtttggt
     9181 aatgatacaa gggatatcct tctggtgaaa aggttccctt tggtgttcga ttgacccaag
     9241 taggatgagc tttagctgtt ccgatagttg tttttccatc cttcttcttg atggtgacat
     9301 ccatgagaac accacgttca gtccacttag cattctcttc atctcccata gattcaatcc
     9361 gttgattgga aatgaagttc cccatttaat agataatgag tttcttatct ccatcttttt
     9421 caaccgtttc agatggttca acaacgtgag gatgccctcc aaagataata tccgctcccc
     9481 aatcgatcat cttgtgataa agagcttttt gttcttcagt tagttccaat cgatactcaa
     9541 cacccatctg aagcatgata atggtgatat ctgcttcctt ctctgcccgt tcaatttcaa
     9601 ccttcatctt atcttcgttt aaatctgaaa gataacgatt atagtcttcc tgagaaatat
     9661 actgctcaat tccattgaaa ccataggaat aggctaacaa tgcaaccttg ataccattca
     9721 cttccttaat gaccagcgga gcctgatcac gtggttcgtg cgtataaact ccgattggag
     9781 tgattccagc tttctcaata atatcggccg ttgaaataac tccctcaatt tgcgaatcca
     9841 aaatatgatt atgagctaaa tccagcacat gataacctgc ctccttaata gcatccataa
     9901 cttcagcagg agcattaaag agaagataac ccgctaaata atgatcctta ttaatggttc
     9961 cttcaaaatc accaatagct aaatctgctg cttagtcccc ttgcttgagc caaggagtca
    10021 catactcaaa attttcatga aagtcatagg taccgtcttc ttttttagct gaaaagaaaa
    10081 gtccatcgtg gtagagcaaa tccccgtggg ccataattct ggcagttttt tcctcttcct
    10141 actcctgaga cttttgctta gtcccctctt gagaaatagt atctcgtttt tgactagtca
    10201 agggattcct tggaagcttt caaacaacaa gaccaagccc attgataaat caactgctag
    10261 caagagtatc gccacaaatc ccttattgct ccacttgcga taactcctaa aaagtttacc
    10321 aagcccttca taaaacgaaa agctaaacca ccctgatttc gattttgtct tctttgtatc
    10381 ttcattctcc ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt
    10441 tctttcacaa ttgaattgaa cttcccatct attttctata aatcctaaat gccataatgc
    10501 tttcaattct tgtcattttg tgatatcatg tagaggaaat gaactaatcc acagtggctt
    10561 attccaagta taccacttgg gctttggcag tagctaactg cactaaacat aatataagga
    10621 gagaaaatgt ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat
    10681 attatccgtg aagggaatcc tactctacgc gcgattgctg aggaagtcac tttcccccta
    10741 tctgaccagg aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagat
    10801 cctgtcatgg ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta
    10861 gatatctcaa aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact
    10921 ccacaggaag cctacgattt ggaagccatt atgtacaatc caaaaatcgt ctctcactct
    10981 gttcaagatg ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct
    11041 ggctatgttg ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa
    11101 caccgtatca aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt
    11161 aacggtatca tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt
    11221 ttactgattc ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag
    11281 gcatgaaaac aaatgatatt gtctatggcg tccacgccgt taccgaagcc ctccttgcaa
    11341 atacaggaaa caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca
    11401 aggaactagc tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa tctctctctg
    11461 agatgactga aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata
    11521 gcgagctaga ttacatcctt gcaaaaacac gccaagaaga aaatccactt ctattgattc
    11581 tagatggtct aaccgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca
    11641 atgtttcagg tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct gtcgttgcca
    11701 aaacagccac aggtgctatt gaacacgttc caattgcccg agtgaccaac ctcagtcaaa
    11761 ccttagataa actcaaggat gaaggcttct ggacctttgg aacggatatg aacggtactc
    11821 cttgccacaa gtggaataca aaagggaaaa tcgccctcat catcggaaat gaaggaaaag
    11881 gcatctctag caacatcaaa aaacaggtcg atgaaatgat taccattccg atgaatggac
    11941 atgttcaaag cctcaatgcc agtgttgctg cagccattct catgtacgaa gtttttctaa
    12001 atagactata aaaaagtttc cagtcatctg attggaaact tttttatgat taactatgtt
    12061 ctgtgataaa cttgtaggct tcttgaccag cgatagctcc atctccaact gctgttgtta
    12121 cttggcgaag gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagtct
    12181 tcatgtggct atctgtcaca atccagcctg cctgatcttg gatattcaat tctttaacaa
    12241 aatcgctaag agggtccaaa ccaacataga taaagacacc accgaaggct tgctctgtca
    12301 cttgacctgt tttcacattt tcaaaaacga cagattctac tctgttttca cccttgattt
    12361 ccttcactac agaatcccag ataaagctga ttttttcatt cgcaaaggcg cgatcttgta
    12421 aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac
    12481 gagtcaagaa gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt
    12541 ggtcacggaa gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt
    12601 cttcttctcc aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac
    12661 gtgtttcata tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat
    12721 tttcaacata accataaatg tgctcaacac caagattttc aagtggttca aacatctttt
    12781 cagccaattc aggtccacta atattagcat atcctgggta attttcgata tcagatgtat
    12841 tattcatctg accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag
    12901 cagcatacaa ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca
    12961 tatagattcc ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg
    13021 caaggattat gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac
    13081 aaccaagact ccaatcataa tcatatcata gagatgggct tggcgagccc cggctgtctt
    13141 atcaactccc gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat
    13201 ggtggtcaag atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct
    13261 catttctatc ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat
    13321 ctattatatc aaatataagt ccgtttgtaa ctagcaaaga attcttttgt ccgctcttct
    13381 ttaggggtgt ggataatctc atccggagtt ccagactcga tgattttccc cttatctaag
    13441 aagagaattt tatccgcaac ttgggctaca aaggacatgt catgactgac caaaatcatg
    13501 gtctgacctg acttagcagc atctgcaata gacttttcta cttcaccgac caattctggg
    13561 tcaagggctg aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc
    13621 gctagggcaa cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg
    13681 tccgaaagcc caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat
    13741 aatttcttga caacaaccaa gccttctttc acattatcaa gtgctgttcg gcgttcaaat
    13801 aaattaaact gttggaaaac catagacaac ttacggcgta gggcaaggat ttcttcttga
    13861 gtgattttag aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt
    13921 tcaagataat tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaatcaag
    13981 gctacaactt cccctttttg aatatccaag ttcagatgat ccaagacagt ctgtcctgaa
    14041 aaggatttgc ttaaattcga aatcttaatc attaacgaag gtctcctttc acatctgttt
    14101 gcactgtatc aggtgcagaa atagccattt ttctctcgat gaaacgaccg aggctttcaa
    14161 ttccgatatt gactacccaa taaacaaggg caacggagat gaagcgttca aaatagcgat
    14221 aatcagctcc acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag
    14281 ctagagatgt tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca
    14341 ccgctgcatt aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc
    14401 gcgccgcctc aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag
    14461 cataagctgc ctcattaaag gcaaaagcga caatcgcaaa agctgcagct ggaatcgcat
    14521 tgatattgag accagttccc cattgctgat tgagggcttt caaagccaaa gggattccgt
    14581 agtaggtcaa catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg
    14641 cctgcaaggg atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca
    14701 aaaccaagcc aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga
    14761 caattctagg gattccatca aagaccgaac gtaggctaaa cagcttgcca tccggaatca
    14821 attgcatcaa gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat
    14881 cctcttctga taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg
    14941 gtcagataca gactttgtct acctactagt ttatcatact ttgaaacagg gaagttatat
    15001 attttatcta tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt
    15061 cgataaccga tttgcttaac agttccattt tctactaaaa tgggccgttt taacaacata
    15121 ccgtcacttg ctagcaactc agccgcttct tggtttgaca aacttcctac cttatctttt
    15181 agccctaatt cacggtattt gataccactg gtgttgaaaa attgcttcaa ttcaaatcct
    15241 gaggtttcta gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg
    15301 gctttataat ccacacttaa ttgatttaat tcttgttttg cttttttaca agttgaacat
    15361 ttggggtatt cgataaattc taacatgtgc ttctccttct atttgtttat atctttaaaa
    15421 tctacgcctt catgctccaa gagccaagct ttcttttcca ctcctgcagc atagcctgtc
    15481 agacgcttgc ctgctcccaa cacacgatga caaggtacta ggatagacca aggattgcgt
    15541 cccactgctc caccaattgc ttgagcagaa gccacttgca ggtcttgagc aatttgtcca
    15601 taggtcactg tctgaccata aggaatgccc tgtaaatagt cccaaactct cttttcaaaa
    15661 ttcgttccga ttggcgccaa gagcaagttg gataaatcct gaggcttgcc tttaaagtaa
    15721 tcatctaagc aagcaataac tgggtctaaa ataggatgac taacaacttc ttctatcgtt
    15781 tcatctccta gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc atacaaataa
    15841 tggtcatcag ctacaagtga tagaatacca attggtgagg agtagagtat ttttacatac
    15901 ttcttttgca ttatttcttt aatttttgat aggccaagcg ttcgccatct actggcacct
    15961 taccaacttg tttaaaacca agtttttcaa aaatatgttg cataaccttg ttttcagcat
    16021 gcgtatctga gcgaaaatca agataatcaa aaccttcaat caagccctct aagaaggttt
    16081 gagcaactcc ttttccctgc acatctgctg ccacagcaat acggtgaaag actagatact
    16141 ctgactctcc agcttgccag tttccctcat aaatagcttc ataggcctcc tctggactct
    16201 tggtcacagc agcataggct agcagttctc cctcttccaa ggctacgtag gcttgccctg
    16261 agatgatatc atcgataata acatctgcat ttggatagcc attttgccac tggtcactac
    16321 cagcatctgc taaacatttt ttggcatcct ccatcacctg catgatggca tctacttcat
    16381 ttggaaaagc taaacgaatt tccatctttt ttcctcattt ctgactagtt tctcccatca
    16441 tagcataatt taagtatttc tacaagcagt taaaacttga ctttgtgttt ttgttatttt
    16501 ataatctagt tatcaaaact atataaaaag gagttgaaaa tgaaaactac cttttcctac
    16561 ccaaaatggg cagaaattcc aaacattgac ctctatctgg accaggtttt gctctatgtc
    16621 aatcaggtct gcgcccctat ctctcctaat aaagacaagg gcctaacagc atctatgatc
    16681 aacaattatg tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata ccaacgccaa
    16741 cagattgccc gtttgattgc tatcacaacc ctcaagtctg tattttctat tcaagaaata
    16801 gcccagacac ttaatactct acaaactcaa gcaagttcag accaactcta cgatgctttt
    16861 gtggactaca tgaaccaagg aattgaccca gctaacccta ttatccaaac cagctgccaa
    16921 accgttaaac tctatcatca aactctagac ttaatcgatc atactcaaga ggaggtaatc
    16981 caatgaacac tagtcttaaa ctcagcaaac aactcagttt tggagaggag attgctaata
    17041 gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt gctgcctatt tcatccatct
    17101 atagttatga agcacacgga tttttatcct ctatcggcgt ttccattttc gtcatcagtc
    17161 tctttctcat gttcctatca tccaccattt atcactctat ggcctatggt tcgacccaca
    17221 aatatgtttt gcgaatcatt gaccattcta tgatttacgt tgccattgcc ggctcataca
    17281 cgcccgttgt cttgaccttg atgaataact ggtttggcta tctgattatt gtcatccaat
    17341 ggggaacgac catctttggt attctctata aaatctttgc taaaaatgtc aatgagaaat
    17401 ttagccttgc tctttacctg attatgggct ggttggttct ggctatcatt cctgccatta
    17461 tcagtcaaac gacacccgtt ttctggagtc tcatggtaac tggcggactc tgttatacag
    17521 ttggagctgg attttatgcc aagaaaaaac cttatttcca catgatttgg catctcttta
    17581 tcctagctgc gtccgtactt caatacatcg ctattgttta ttacatgtaa aaaagttgag
    17641 aaattcaatc tcaacttttt tctttacaca tattgataaa gtactggtgc aagcgcacat
    17701 catcagtcaa ttctggatga aaagaactta ccaacatatt tttttcttgg gctgcaacaa
    17761 tttgattgtt cactgttgct agaatttcta caccctcacc aacactactg ataatcggac
    17821 cacggataaa ggtcattgga atcttgccaa ctcccttaca ttctgcttcc gtgtagaaac
    17881 ttcctaattg gcgcccataa gcattacgct cgaccaccat atccatagtt cctagataac
    17941 tctctttctg agaagtgatt tccttagcca gcaaaattaa gcccgcacag gtcccaaaca
    18001 ctggtaagcc agatagaatg gcttctcgga tgagaagtag catgttctgg tcacgtaaga
    18061 gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa acccgacaag tcactctgat
    18121 cttgctgaaa atcatctaga tttctgagtt ctacactctc gacacctaat tgatctagca
    18181 cttttgcatg ttctgcaaag gccccttgca aggccaatat tccgattttc atctattttc
    18241 ctcgttcagc catgagaatt tggatttcat tttcattaat accaaccatg gcttctccta
    18301 aatcttcaga gatttgagct aggatttgag gattacggaa gttagtcaca gccttaacaa
    18361 tggcactcgc tcgtttaaca ggatctcctg acttgaaaat acctgaaccg acaaagaccc
    18421 cctctgcccc tagttgcatc attaacgcag catctgctgg cgttgcaaca cctccagcag
    18481 cgaaatttac aactggcaat tttccatgtt catgaacata ttggaccaat tctacaggga
    18541 cttgcaaatc cttggcagca acataaagct cgtcctcacg taagttttga atgcggcgaa
    18601 tttcctgatt catcatacgc atatgacgaa cagcttggac gatatcccct gtccctggtt
    18661 ctcctttggt acgaatcatg gaagcacctt cagcgatacg acgcaaggct tcacccaaat
    18721 ccttagcacc acagacaaaa ggaacttgga attctttctt gtccacatgg aaacggtcat
    18781 cagctggaga tagaacttca ctctcgtcga tataatcaat ttcaatagcc tctaaaatct
    18841 gagcttcaac aaaatgcccg attctgacct tagccattac tggaatacta accgcttctt
    18901 ggatttcctt aatcatcttt gggtcgctca tgcgggaaac tcctccagct gcacgaatat
    18961 cagccggaat tcgttccaag gccatcacag ctgccgcacc agcagcttct gcgatacgag
    19021 cctgttcagg attctgcaca tccataataa caccaccctt gagcatctgt gccaagtttt
    19081 tatttagttc ataacgattt tcagtcattt gttttatcct catcatttgt attggtagct
    19141 accttttcat tttaagtcag aacagaatga agcacaagat aaaaaaacta taattgtatg
    19201 gggacaaatt agctaaaaac tatctgacct taacttaagg ccagatagct cattcatttt
    19261 tatttttcag ccgtaagggc agccattgtg atgtagttgt atggtttgtt gaagtgtggc
    19321 aagaagaaga ggtctgtcaa tgccaattta tcaattgtca catgctcttg gatagcaagt
    19381 gagaacatgt ggattcccat gctaattgca atatcatgtg aaaccatttg ggcaccaaga
    19441 atttcacggc tatctttgtc aaagacaatc ttaattgcta cttcatggtt gtcatgtttc
    19501 atgaattctg gtttttgaag atcgttaaag cctgtttcag ttgcgttgta accagcagct
    19561 ttcgcttttt caagagtcaa accagttgaa accatgtgaa gaccgtagat tgagatacca
    19621 tttgaacctt gaacaccgat tccttccaat tcatgtccac aagcattgta ggcaccaacg
    19681 ataccagtgc gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt acgagcattg
    19741 tcataaacag tcgcacagtc accaacagcg taaacgcctg ggatagatgt ttcttgtttc
    19801 ttgtctacaa ggaaggcacc gttgcggaag agttcgatct taccatctgc aagggctgtg
    19861 tttggacgga aaccaactgc aaggataacc atatccacgt caaagctttc tttgtcagta
    19921 atcaagcgtt caactttacc gtcaccttcg attgctttaa cagtttgacc tagagccaag
    19981 cggatgttgt gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt gtcatagtaa
    20041 ccgttcaaga cagtatcaac gatatcaaca aggacaactt cttttccaag acgttcaaag
    20101 gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa cggcgatacg gtcgaggtgt
    20161 tggctcttgt cagaaagttt attgataact tcttcagcat tttggtacaa tttcacgaat
    20221 tgtacgtttt caagagttgc tttaaattcg cggtttcctt taacaatttc aacaccttcg
    20281 attggtggca agattggtgt agaacctgta gcgaaaatca atttttcgta tgattctttg
    20341 tgctcttttc cttcaacttc cgctgtaact actttgttat catagtcgat tgaaagaaca
    20401 ggtgagttca tgtaaacttt agcaccttta gcttccaatt tttctttatc agaatagaac
    20461 aagccttcag caccgtcaat ttgttcacca atccaaagag ccattccaca tcctaggaaa
    20521 gagatgttag agttttggtc aaatacaaca atttcgttct catttccaaa attatccaac
    20581 atggtattga tacatgctgt accagcgtgg ttagcaccga ctacaacgat tttactcata
    20641 aaaatttcct gccttcattc taaatttacc ttactagtat accatttacc gttagcgttt
    20701 acaagggggg tactattatt tcagcatttt ttatcaaaaa taattcccca tttatcctgt
    20761 tttcaagcct catgaatttt atgagcatat ttcttgactt tttccaaatt ttgtttgtga
    20821 aaattctaac tttatggtat tataataaca tgaaaatgaa atgtaagggc ttcaatttag
    20881 atgattattt gatattacaa cttattttct ataagagaaa ggagttggta gcttgactct
    20941 tcgttcacat tctgaacggc taatggggac tactatcact atttcattag tggatgagca
    21001 agccgatatc tttctccaaa aatcctttga cttgctcaaa gagcttgaat accgcttcaa
    21061 cgccaatagt caagaatctg agttgatgga aatcaattat caagcaggaa tatcccccgt
    21121 cacggttcat ccagacctgt ttgagctgat ttcacttggg ttagagcata gcctagcgct
    21181 ctctagccac ctcaatatca gcattggtcc cttaattcaa acctggcgta tcggtttttc
    21241 agatgccaag gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa tcaatcctca
    21301 tggtatcgag ttagattctt ctacttctac tgtgttttta aaacagaaag gaatgaagat
    21361 cgatctaggt tgtttagcca aaggatacag tgcggataag gttgcccaat ttcttaggaa
    21421 agagggggtg acttctgcct tgatcaatct gggagggaat atcctgacca ttggaaaaaa
    21481 tcaggcaaga ggggataacc catggcaaat cgggattcaa gacccagcca atccgagggg
    21541 aaatcattta atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag gcatttatga
    21601 acgtcacctg accgtcgatg gacaagatta ccatcacatt tttgacagtc aaacaggata
    21661 tcctgttgaa acggaactag cgagtctaac aatcatctct gataaatcag tcgatggcga
    21721 aatctggacg actcgactct ttggagaaag acctgcttct atcttctggc aagtcgaaag
    21781 tttggagggc atcgaagtca tcctcatcga taaagaaggc cacctaagct gttcttcagg
    21841 aattcctact ctatagagac aactgtttca atggaatttt aaaattgtat tatgtaaaaa
    21901 gagaaaggaa atctcatgtt aaaacttatt gctattgttg gaacaaattc aaaacgttct
    21961 acaaaccgtc aattgcttca atacatgcaa aaacactttg ctgacaaagc tgaaattgag
    22021 cttgttgaaa tcaaggccat tcctgtcttc aacaaaccag ctgacaagca agtacctgct
    22081 gaaatattgg aaattgctgc taaaatcgaa gaggcagatg gcgttattat cggtactcct
    22141 gagtatgatc actctattcc agctgttttg atgagcgctc ttgcttggtt gtcttatggt
    22201 atttacccac ttttgaacaa accaatcatg attacaggtg cttcttacgg tacgcttggt
    22261 tcatctcgtg cccaattgca acttcgtcaa atcttgaatg ctcctgaaat caaggcaaat
    22321 gttcttccag atgaattctt gctctcacac tctcttcaag catttaaccc aagtggcgac
    22381 ttggttgacc ttgatgttat caagaaattg gatgccatct ttgatgactt ccgtatcttt
    22441 gtaaaaatca cagaaaaatt acgtaatgca caagaattac ttcgcaaaga tgctgaagac
    22501 tttgactggg aaaatttgta agataggaga ccaaaaagaa tgaaatttgt tggacttgtt
    22561 ggatcaaact acgatcaatc atataaccgt aagctcttgg aatttatccg tcgctacttc
    22621 aaactcaaat ttgaattaga agttcttgaa attgacgaag ttccaatgtt taaccaagat
    22681 gaaaaatggg atgaaagttt ccaattacgt tatttatata acaaaattac tcgtgcagat
    22741 ggtgttatca ttgctactcc tgagcataac cacactatct cagcttcact caaatctgta
    22801 cttgaatggc tttcatacga agttcatcca tttgaaaaca agcctgttat gattgtgggt
    22861 gcatcatact atgaccaagg aacatcacgt gctcaagttc accttcgtaa aatccttgat
    22921 gctccaggtg ttaatgccta cacgcttcca ggtaacgaat tccttcttgg taaagctaag
    22981 gaagcttttg ataacaacgg aaatatcacc aacgaaggca ctgttaaatt ccttgaaact
    23041 tgcttagata actttgttaa atacgtagga gtcgtttcga aattgaaaaa accaaaacca
    23101 atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta caaccatcac agaagttgac
    23161 cctgacgatc cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt ttctggtgat
    23221 acctatgtca aattggacca cggtatccta acagttaacc aaattgatat gttcttgaaa
    23281 gctatgccat ttgaattgac atacgctgac gacaacaacc aattcctcta ctacaacaac
    23341 gctcaccaag atccagacac tatgttcgct aaacgtgtac cacctcaatc aggtagccgt
    23401 atgtcgactg ttcatggttc tcttccacca gcacgtatga agaacgtaga gtgggttatc
    23461 ggaacacttc gcaacggaaa ccaagaatac gtccgtacga tcgttccagg ttctcctgca
    23521 ggtgttatca acactcacaa ctaccaagca atgtactatc ctgatggatc atacgctggt
    23581 atcaatgaaa tcgtctttaa cttccaacca tggcttgact ggtacctaaa agagactggt
    23641 caacgtttgg tgggtggtag cggaccattt gctcctgctg ccggaggtca tggagacgcc
    23701 gatgctactt ctggcgcttc tgattcaggg gatgctggat gccacggtgg tgacgcagac
    23761 gctacagccg gtgcaagtta ctaatgatag tttttaggaa ccattatggt tcctttttag
    23821 cgaaaaaaga ctagcaaaca caaactgcta gtctctttgt tatcgtttca tctatctttg
    23881 ttaaaagaaa gaatacatat tatgaatttg gatcatcaag actacggcca tgtaatcctt
    23941 tttcacgttg tacttggcgt agtttttctg gtgtaacatc gtttccttct tcgtccacaa
    24001 ttttgattcc ttcaatgtgg tgacgaacag cgcggcgata accttcgatg tactcctcac
    24061 gtagtttggc ttgttccact ttttcttctg gtgttaagcc ttctgttttt ttctttttag
    24121 caagctcatt gatacgagca atttttttcg gatccatttc ttctcctctg taataagata
    24181 aagtccgttt atcaaatttt atttagtgtt aatttggtta aaacaagcaa acttagctgc
    24241 tttcttggtt agttgtgaca agattgccaa acgattttga cggacagcct gatcttcagc
    24301 cattaccata gtattttcaa agaaagcatc aatgactggg ctaagcgcaa agagttgttt
    24361 caattgctga cttgcaggtc ctgataaaac gagtgtttct actgcttctg ccaaagcttt
    24421 ttcttggtca ttctcaaata gtgctgaatc aactgtagca accccttctg ccttctcagc
    24481 caggttaaag gcacgagaaa gtgattcaac agatggttta aaatcttctt ccttgcttac
    24541 ttctacgaga gcacttgctg cttccaacat atctgccaca acaaagtttg aacctgcaag
    24601 aactgcttcc ttgatatctt ttggagtaga gcccatcatc ttatcaacac gagccttgat
    24661 aaagtccata acctctgctt tattttcata agtcaaactg tcaaatttca atgcataaag
    24721 gctatcaatc agctcatcca tagcaatgtg ccaaccaaag gcatccaaga tacgaaccac
    24781 accttgagtt gcacgacgaa gggcataagg gtcattagaa cctgatggaa tcaatcctac
    24841 tgagaagaaa ctcaaaatcg tatccaattt gtctgcaatg gctagaactg caccgacctt
    24901 gctctctgga agttctcctt cagctgatgt aggcatgtag tgttcacgaa tagcagctgc
    24961 caccgctgga gtttcaccag caagaagggt gtatttttca cccataattc cttggagttc
    25021 gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg ctgcacgagc
    25081 aaggtcaact gtttcatcca ctgacaaacc agctttttct gccaaaagta cagtgatttg
    25141 acccgtacga atcatgtgtt cacgaaggga accaatcttc tcatggaagg tgacattgtt
    25201 taatttttca acaagatctg aaatcaccaa tttttggtct tcacgccaga agaattctcc
    25261 gtcttccaag cgggctacca agactttttc atttcctttg atgacatttt tcaaacgctc
    25321 tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt tttccatctt gatcacgaac
    25381 aacaaagtaa cgctggtgtt ccttcataga agtcaccaag acttcttctg gaacttcaag
    25441 gtatttagca tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat tcaagacttc
    25501 attcagcaaa tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa ttttcttgat
    25561 ttggtcaaca atcatttgct cacgttcaca tggatctgcg attacaaact gcttacgaag
    25621 gtcttcttca tagctcaatg ctgactgaat tttggtttct ttccccaaga aacgatggcc
    25681 acggctcaca cgacctccct tgatatcaag gaaatccaag tcaaactctt gctcatccaa
    25741 gagaacagtt aaagtgtgaa cagggcggat gtattcaaag ctatttccag cccagtgcat
    25801 gctgacaggg aaagtcaatg acttcaagac atctacaaca ccaggaacaa tggcttcaac
    25861 tgcttgacca acttcttcct tagtgacata gacatattct tcacccttga tttcacggaa
    25921 ttcgatatct tcaacagtca agccttttcc acggacaaat ccttgagctg ctttggtgaa
    25981 gtttccatca ctatccaagg caatttcctt tgctggtccc ttgaaatctt ctgtcaaatc
    26041 agactgtttg tctgataaac cagtcacacg aacagccaaa cgacgtggtg ttgagaaggt
    26101 ttgaatggct tcaaaagaca ggcggttttc cttgaggaag gctgccattt tttcgcctag
    26161 ttgtttttca cttggtgtga caacataggc tggtaattct tcaagaccga gttctactaa
    26221 taagtttttt gtcatgtttt ttctccgaaa agtatctttt tattttccag tttgccttat
    26281 gtgattggca cgcaagcaac caacttcgtt gtttcattgc taaaattgga gccaaaagtc
    26341 tccaattttg cctagtatcc ttagtttcac taaggatacc ttcatcactg cggcaactga
    26401 ctcagggctc actctgttcg cccattttcg taatttgtca ctctctttat tctgcgtctt
    26461 ctgctaggag tttagctctt gtttcttcat ccaaaagtgg gtaacctagg cgtttgcgtt
    26521 ctgcaacaaa ggttttggct acaacacggg ccaagttacg gatacgagcg atatagcctg
    26581 cacgctctgt tacagataca gcaccacgcg cgtcaagcag attaaaggta tgtgaacatt
    26641 tgagaacata gtcataggca gggtgtacca agccttcttc taatgcacga ccagcttctt
    26701 tttcaaactt atcaaagttt tcaagcaaca tttcttggtc cgaaatttca aatgaatatt
    26761 ttgagtgctc atactcaggc tggataaaga tttctccgta ttttacacca tcagcccact
    26821 cgatatcata gacagagtct acttcttgaa tgtaagaagc caagcgctcc aaaccatagg
    26881 taacttccgc agtcacaggg ccagttgcca atccaccgac ttgttggaaa taagtgaact
    26941 gagtgatttc cattccgtca agccaaactt cccaaccaag accagctgaa ccagttgatg
    27001 ggttttccca gttgtcctca acaaaacgaa tatcgtgctc caaaggattg attcccaatt
    27061 tttccaaaga ctcaaggtaa agttcttgga tatttgatgg agaaggcttc atgaccacct
    27121 ggaattggtg gtgttggtag agacggttag ggttttcccc ataacgaccg tcagcaggac
    27181 gacgtgatgg ctctacataa gctgcattcc atggctcagg tccgatagca cgaaggaaag
    27241 tgtaaggact cattgttccc gcaccttttt cattatcata agcctgcata agcatacaac
    27301 cttggtcatt ccaaaattgt tgcaaagtaa ggatgatttc ctggaaagtc aatttcttag
    27361 acattgttta ctccttttta tataaattac ttgcgacatg agtctgcctc gtcgatcata
    27421 cgaggcaaga cgagttagta ctgcgtctag ctcaggcact ctagtgctga gcgtggggca
    27481 gtccgactgt aaggaggttt ctgccactga tgcagtaaaa tgttaatttc ttagacattg
    27541 aatactcctt aataaaaaat gatttcttgc gacacgagtc tgcctcgtcg attatacgag
    27601 gcaagacgag ttagtactgc gtctagctca gcaccctagt gctgagcgtg gggcagtccg
    27661 actgtaagga ggtctctgcc actgatgcag tgaaatgtta atttcttaga cattgtttac
    27721 tcctttagtt tttatatttc tttttcaatt aatttctgct gaacaaacca atctaacaag
    27781 ggaaaaattt tttctgtatt tgcccataaa tgataagaat ctaagaccgc ttgtacacta
    27841 cctaaatttt ctaccaactt atctactgtc aaaaagcttc gccagtattc ataaaaaata
    27901 cttgcatagt tcttatcata agtcgaagaa ccaaaatcat tcaatgaatg ccaaccatac
    27961 ttcttctgaa aaagttctac gagagattga ttacaaattt tttccgcttg aaattcctct
    28021 tctgtaaaga aatacttgcg actaatatat tcaaccatcc cctcttcgaa ccagatataa
    28081 gagtcataac catcaaaatc atctaaaaaa tgctccgacc aatgagctaa ctcatgtcct
    28141 acaatctgta agaggaaatt ttcagataaa gaatgatagt gactttctat tgcttgagtt
    28201 tgctcagaac actcgtagtc catcaattga tacaaataca actctttcca aacagctaaa
    28261 tcaggcgcca taaccattcg tctattattt gtataggctg gaacagcgct ttccctaata
    28321 atctgtgtag cagcattaaa atctgaccaa ataacggctt gcggtaaatc acagactgca
    28381 agttcattct ttaaaaaaga ttgataatct ttcaactttt cagtatttct tactacaaaa
    28441 tcacgaaatg tagctagttg actatcgtct tttacaagat aaaggttgtc cacggctctc
    28501 ctttctttca cacaatagac tgaataagca aaagaaccgc gtccgacaat cctaggttga
    28561 tttaacctag gggcgtcaga aacgcggttc caccctaatt tattacttca ttgtttttga
    28621 aaatactaca gaaagcgcca gctcattatt ttgccctact tggctcccac tatcccaagc
    28681 tcgcttgaag aacgccataa gactttcttt cctgctgact attatatcaa aaattagaat
    28741 aatgtacaat tctttttatg attttctaga aatccacatc atcaactcgt ggagcacccg
    28801 attgaacagc aatcgttttt aaggtttctc tctcctcatg actcagttca attccaaagc
    28861 aatcaagatt agcttgaata cgagaggttg tgacagattt tggaagtggt aaaaatcctt
    28921 ctgccaagct ccaggccaag gctatctgag caatcgattt tccgtgattt gctgcgattt
    28981 cttgcacttg cttgctatca aatagttctc cctgaccaaa aggcccccaa gcttccaata
    29041 aaattccctt ttcacgacag taagctacga cttgatcttg atacacacct ggcgccaagc
    29101 gaacttgatt gaccgcagga acgatagttg cagtttcaag caaggcatcc aaatgatggg
    29161 gaagaaaatt gctaacgccg atagcacgga ttttcccttc ttgatagagg tcttccatcg
    29221 ctctccaaac ttccgcattg cgagttttcc atgcgtcatt ttctctgagc ggttttgggt
    29281 tcggccaatg aatcaaatac aaatccaaat aatccaagcc cagtttttct atagattttt
    29341 ccaaagcttg acgagtttgc tcataggttt gctgactatt ccaaagcttg gtagttacga
    29401 acatttcttc acgtggaact ccgctatctt tgattgcttg accaacactt tcttcattct
    29461 gataaatcgc cgccgtatca atatgacgat aaccagcctt caaggcttct aacactgcat
    29521 gataggcttc ttctccatcc ttagccttaa aagttccaaa tcccaatact ggaatttcta
    29581 ctccattatt taattgatag gtattcatat gcttctcctt ctattttatt catcaattat
    29641 agcataagac attttttaag tagtactatc ttctgtaaaa aataagtctg tcaaatatct
    29701 aacagaccta ttttttcttg cttattcatc acgactatag tacagctcat gagcttttag
    29761 gcgagtattg agcatctctg gtatggtcac aaaggtataa ccttgatttt tcaaatactc
    29821 aatgaccctt ggcaaggcat tgactgtcgg actgtgaata tcatgcatca aaacgataga
    29881 gccgttagct acttgatgct gaatttctgt caaaatagat gcttcatttt tactcttcca
    29941 gtccagacta tccacatccc acatgataaa gctcaaatcc aagctattgc gaatatcatc
    30001 tgtaatagca ccataaggtg gacgcatgag tttagaacta gaacccagca ctttagttag
    30061 cacatcctca gtatcagtaa tctgcttttt agcttcatca agagagagtt gcgagagaat
    30121 cggatggctc caactatggt ttccaacaac atgaccttca gattttatcc tcttcaccaa
    30181 gtcctcattc ccagaaacat ttttcccaag cacaaagaaa gtcgctttaa tatcatattt
    30241 agctagggtc tctaatacct gcggggtcgt tgctggattt ggaccatcat caaaggttag
    30301 agcgacaact ttttgatatt tcttatcaaa gtaagattga tacaaggccg catctttttc
    30361 gagtaagtac gaagattgga taacatcaaa gaaagcagat actggcaagg ctatctcttc
    30421 taaattttca agcacaggac ttgaataaag gataatctga ctatccttgt aatcaaaatt
    30481 ccatgcagac aagtcttggt cagagaagct ttttacaatc tgctcactct ggtcttgctc
    30541 tattttttta tcctctatga aggaggtcaa ctcttttatc agctgttcct tagccttact
    30601 agcatctgaa aacagttggt caagtgtaaa aggttgccca tcttctgtta agtgaacctt
    30661 tcctagactg gtcttttcag tctcttcaac cttaaaagca actaaatcat agatttgttt
    30721 ggtcacatta cgattaacga ctccctttaa acctgactct tcttgctctg tatagtagaa
    30781 aacaagattg tccttacttt ctagcttgtc cttaacatct tgatttatca actccctaac
    30841 agaggaaatc actttctccc cttggagagg ataataggca atcacttcgg cttgcccctg
    30901 acgaaaatgc tccttctgat ttccctcact caattgatca tctttctctt ttttgagcga
    30961 ttcaatcttt tgctcaaaac ttttttgctg gtagatctta aaagcaataa atccgcctaa
    31021 taggcaaata gaaattgcta agataccaat caaagccaat aatacatgtc tcgttttccc
    31081 gtgtctgcca cgtcctagtc tacttttatt catatttata tcataacaaa tttgagcaat
    31141 aatttcaatg atacaatttg gcaatccaca attcctctag caagccaaag catcttacat
    31201 caactccaac atccgtatct gtagagatta tgtagttttc tatctatgga atttctagta
    31261 aattgaagct agaatagtag acctatactt ctaaaacatt gttagaaatc gatttgattg
    31321 tcctgatcga tttgtcctgt tcttatttca ttttactata aaactatgaa aagctaggtc
    31381 atctgagaag taattactat cgacaattgc gatagcgtat actggtgcga tttgtttgta
    31441 gctctggtgg gtatcacctt cacgttggcg aattttttct aggttttgat taacctgact
    31501 gcacagataa gcccataggc gattgatgaa aaaattctga tgatgaacct gaatttcgat
    31561 gataacttga attccattat ctaactccgc caagacgtct atactagtat agaaatcctg
    31621 cgctgagtag gacatggaag gcaagacgtg aatgttactt ccctccaaaa tcgtcacatt
    31681 ttttgctggc aagtccagca tatcgcggat aaattgacaa atcattagtt gggctgatac
    31741 ccggatgtct gagaatcctc cttttcctcc ttctattata gcacattttt aaatctaggt
    31801 ttgctagatt ctatgcttct atctatttat tcggaaaaga aagcttttct tcagaagaaa
    31861 gctaatagct tatttgaaat tttctcctct ctgttggata gtcccgtcta tctatgttat
    31921 aatgaaagaa ggatttaaaa tcggaaaagg agtatttatg ctaaaattag gtgtcatcgg
    31981 aactggcgct atcagccatc atttcataga agcagcccat accagtggag aataccaact
    32041 ggtcgcaatc tattctagaa aactagaaac tgcagcaacc tttgcttctc gctatcagaa
    32101 tatccaacta ttcgatcaat tagaagtctt cttcaaatct tcttttgatt tagtctatat
    32161 cgccagtcca aactccttac attttgctca ggcaaaagct gccttgtctg ctggtaaaca
    32221 tgttattctc gaaaagccag ctgtcactca accacaagaa tggtttgatt tgattcaaac
    32281 agctgaaaaa aataactgtt ttatctttga agcagctcgt aattaccacg agaaagcctt
    32341 tactactatc aaaaactttt tagcagataa gcaagtgtta ggagcagatt tcaactattc
    32401 caaatactct tccaagatgc ctgacttgtt ggctggacaa acaccaaatg tcttttcaga
    32461 ccgttttgct ggtggagccc tcatggattt ggggatttat cccctctatg ctgctgttcg
    32521 tctttttgga aaagccaatg acgcgactta ccatgctcaa cagcttgaca atagcattga
    32581 cctaaatgga gatggtaccc tcttctaccc agactatcaa gttcacatca aggctggaaa
    32641 aaacatcact tccaatcttc cttgcgagat ttatacaaca gatggaacct tgactctcaa
    32701 cacgattgag catattcgct cagctatttt taccgaccac caaggaaatc aagtccagct
    32761 tcctatccaa caggatcctc atacgatgac tgaggaagtc gctgcatttg cacacatgat
    32821 ccagcaacca gatctgaatc tctaccaaac ttggctgtat gatgcaggct ctgttcatga
    32881 gctactatat accatgcgcc agactgctgg cattagattt gaggcagaaa aatgaaaacc
    32941 aaactaccga ctgaatggca agaactgagt gaccaactcg gtttccaaga attcaccctc
    33001 attcaaactc aactatttga gccccttctt gctggagaaa acctcctagg agtgagccaa
    33061 accggaactg gtaagaccct agcgtatctc ctaccaagtc ttctcagact acaaaagaaa
    33121 aaagcccaac aactcttgat tctagcacca aatacggaac ttgctggaca gatttttgat
    33181 gtatgtaaaa cgtgggcaga agctatcgga ttgactgctc aactcttcct ttcaggttca
    33241 agtcagaaac gacaaattga acgccttaaa aaggggtcag aaattctgat tggaactcct
    33301 ggccgtatct ttgaactcat taaacttaaa aaaatcaaga tgatgaatgt ggaaaccatc
    33361 atcctggatg aatttgacca attactagat gattctcaga ttcactttgt agaaaaaatc
    33421 actcactacg cacctcgtga ccaccaactg gtctacatga gtgccacgac caagtttgac
    33481 caagaaaaga ttgtgccgaa tacacgcact attgatctct ctgatcaaaa attggacaat
    33541 atccagcatt tctacatgca ggtagaccaa cgtcatcgag tggatatgct acgaaaactg
    33601 gctcatgtag aggatttccg tggtctagtc ttcttcaata gcctgtcaga ccttgggaat
    33661 gccgaggaaa aactacagta tcgtgatata ttggctgttt ccctcgctag tgatgttaat
    33721 gttaaattta gaaaaatcat cttagaaaag tttaaagata accaactaac cctgcttctt
    33781 gcaactgacc ttttggctcg tggaattgat atcgatagcc tagaatgtgt cgtaaacttt
    33841 gatattccta gagatagcga aacctacaca caccgtgctg gccgtactgg tcgtatgggc
    33901 aaggaaggtt atgttatcac tctcgtcact catccagaag aaatcaaaaa acttaaaaag
    33961 tttgcaagta tccgagaaat tgtcctaaaa aaccaagaac tctatatcaa ataaagccct
    34021 attgctctat acacatccag tgtatggagc ttttttataa gcaattcaat tttatactca
    34081 tctgctttca aaaagcattc tagtccattt ccgattaacg atggacttta tcacctcctt
    34141 ctccagtcct tgtatgacat cttccaaagt tcgaaaggct ttattcttaa atccacgttt
    34201 acgaatctct ttccacactt gttcaatggg gttcatctct ggtgtgtatg gaggaataaa
    34261 tgcaaagcca atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc
    34321 cataacgagt aaaaaataat catatggata agcttgtgaa agctcttcta aaaagacgtt
    34381 catccactca gtattacatc caccagctat taagaaaaat gattcgcttg tataggcatc
    34441 aacagctcca taacaatagc gaaattctcg tatatagtga ctatggacat gtggacctac
    34501 tcctattgga gaccaacaag atcccagttt actgattcta ccgaaaccag cctcatcttg
    34561 gtacatcaag cgaaccttat gaaaacatct actagtttta aagcgctttc ttgtcttctt
    34621 gaattgagat tttattttta gacgcgacaa tggtttgagc gtc
//
LOCUS       DBERAE010000018        34316 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.18, whole genome shotgun sequence.
ACCESSION   DBERAE010000018 DBERAE010000000
VERSION     DBERAE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.18"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(175..1161)
                     /locus_tag="ACL70N_001063"
     CDS             complement(175..1161)
                     /locus_tag="ACL70N_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0589875.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1171..1971)
                     /locus_tag="ACL70N_001064"
     CDS             complement(1171..1971)
                     /locus_tag="ACL70N_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGS0589876.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2224..3066)
                     /locus_tag="ACL70N_001065"
     CDS             complement(2224..3066)
                     /locus_tag="ACL70N_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGS0589877.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3068..4360)
                     /locus_tag="ACL70N_001066"
     CDS             complement(3068..4360)
                     /locus_tag="ACL70N_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGS0589878.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4471..5742)
                     /locus_tag="ACL70N_001067"
     CDS             complement(4471..5742)
                     /locus_tag="ACL70N_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0589879.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6276..7808
                     /gene="malQ"
                     /locus_tag="ACL70N_001068"
                     /pseudo
     CDS             6276..7808
                     /gene="malQ"
                     /locus_tag="ACL70N_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            7834..10092
                     /gene="glgP"
                     /locus_tag="ACL70N_001069"
     CDS             7834..10092
                     /gene="glgP"
                     /locus_tag="ACL70N_001069"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGS0589880.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11137..11709)
                     /locus_tag="ACL70N_001070"
     CDS             complement(11137..11709)
                     /locus_tag="ACL70N_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589881.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            11787..11993
                     /locus_tag="ACL70N_001071"
     CDS             11787..11993
                     /locus_tag="ACL70N_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589882.1"
                     /translation="MLKKYFSKYKWTDLFWILFVIGACLLTGNSSLFPLTHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(12334..13182)
                     /locus_tag="ACL70N_001072"
     CDS             complement(12334..13182)
                     /locus_tag="ACL70N_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGS0589883.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13334..13612
                     /locus_tag="ACL70N_001073"
     CDS             13334..13612
                     /locus_tag="ACL70N_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGS0589884.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13614..15677
                     /locus_tag="ACL70N_001074"
     CDS             13614..15677
                     /locus_tag="ACL70N_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS0589885.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15755..17011)
                     /gene="tyrS"
                     /locus_tag="ACL70N_001075"
     CDS             complement(15755..17011)
                     /gene="tyrS"
                     /locus_tag="ACL70N_001075"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGS0589886.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17153..19618
                     /gene="pbp1b"
                     /locus_tag="ACL70N_001076"
     CDS             17153..19618
                     /gene="pbp1b"
                     /locus_tag="ACL70N_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGS0589887.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLCFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLATADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19683..20594
                     /locus_tag="ACL70N_001077"
     CDS             19683..20594
                     /locus_tag="ACL70N_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0589888.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20824..21522
                     /gene="dapD"
                     /locus_tag="ACL70N_001078"
     CDS             20824..21522
                     /gene="dapD"
                     /locus_tag="ACL70N_001078"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGS0589889.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21590..22720
                     /locus_tag="ACL70N_001079"
     CDS             21590..22720
                     /locus_tag="ACL70N_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGS0589890.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22732..23271
                     /locus_tag="ACL70N_001080"
     CDS             22732..23271
                     /locus_tag="ACL70N_001080"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGS0589891.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23255..23932
                     /locus_tag="ACL70N_001081"
     CDS             23255..23932
                     /locus_tag="ACL70N_001081"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGS0589892.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23999..24898)
                     /gene="galU"
                     /locus_tag="ACL70N_001082"
     CDS             complement(23999..24898)
                     /gene="galU"
                     /locus_tag="ACL70N_001082"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGS0589893.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24920..25936)
                     /locus_tag="ACL70N_001083"
     CDS             complement(24920..25936)
                     /locus_tag="ACL70N_001083"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS0589894.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26148..26588
                     /locus_tag="ACL70N_001084"
     CDS             26148..26588
                     /locus_tag="ACL70N_001084"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0589895.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26711..27133)
                     /locus_tag="ACL70N_001085"
                     /pseudo
     CDS             complement(26711..27133)
                     /locus_tag="ACL70N_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="ACL70N_001086"
     CDS             complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="ACL70N_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS0589896.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="ACL70N_001087"
     CDS             complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="ACL70N_001087"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0589897.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="ACL70N_001088"
     CDS             complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="ACL70N_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS0589898.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDIMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="ACL70N_001089"
     CDS             complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="ACL70N_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS0589899.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30403..31278)
                     /locus_tag="ACL70N_001090"
     CDS             complement(30403..31278)
                     /locus_tag="ACL70N_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGS0589900.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31445..32776)
                     /gene="pnpS"
                     /locus_tag="ACL70N_001091"
     CDS             complement(31445..32776)
                     /gene="pnpS"
                     /locus_tag="ACL70N_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGS0589901.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32777..33484)
                     /locus_tag="ACL70N_001092"
     CDS             complement(32777..33484)
                     /locus_tag="ACL70N_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0589902.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33568..34053)
                     /locus_tag="ACL70N_001093"
     CDS             complement(33568..34053)
                     /locus_tag="ACL70N_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGS0589903.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34039..34316
                     /locus_tag="ACL70N_001094"
                     /pseudo
     CDS             34039..34316
                     /locus_tag="ACL70N_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        10126 a         6471 c         7349 g        10370 t
ORIGIN      
        1 ggctagcttc ctagtttgca ctttgatttt cattgagtat aaaaagatct tgggtaacaa
       61 ctcaatttca gtagaaaagg aagtaaatct tcccacaata aaacgcatag tatcaagttt
      121 tttcaatacc tgatactatg cgtttttgct tttaacgact ttttgcccag tctcttattt
      181 ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt ttttattatc
      241 attaataatc tggagaatag tttcaaggga aacacgacca agctctaaac tattgatatc
      301 gacataggct gccaagttga gcttgggatt aaccgagtca aagctgagaa cagggacatc
      361 cagctggtgt ttggcaatat agttacaaac accttcagct aggaggctat cggttgtgat
      421 gatagcatca atttgtggat cgtgcttgaa taatcgcttg ctaaatttat agcccttttc
      481 ttccagaaac tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt tgtaatgttt
      541 aagcgcctgt tcatagcctg ttaaacggtc tttggtcacg aagagctttt tacttcctcc
      601 gataaaggca atgcgtttgc agcctttttt gatgaaatat tcagtcgcat caaaaccagc
      661 ttgaacattg tcgttgtcga caagtgggat gaaaggagat agagatttac ctaagataag
      721 gaaggggaac tgttcttctg cgacgagttt tacgagaggg tcttcttctt gggcatagag
      781 aaagattagc ccatctacac gcttgccgta gaccatttgt gaaatagcgt tgagacgctc
      841 cttctcatct ttccctgttg ctatctgaat ggcatagtgg ttttcagatg cgacttgaga
      901 gatgccacgt agaaccgatg gaaagaaagg attctggtag aaggcgtctg agtcatcagg
      961 aagaactaat ccgataacct gagtatagct gcttaccaag ctacgagcgt tgaggtttgg
     1021 gtggtagttg agttccttca tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt
     1081 tgatttattt tgaataacac gggttacggt tgaaggcgaa acaccagcag ccttggccac
     1141 gtctttaatc gtaacgggca taaaaatctc ctatttatgg taatttggat cacggaaatg
     1201 tgttttataa aagatagtga ccagatacag aacaaaaaga atattttgta cagtaatcag
     1261 ggttgtcata ttttggccaa ataatcccaa aataagtgta atcagagtcg gcaatcctaa
     1321 acagttcaag ataaagtgat agcactcttt aaaggttcta aatgaaaaga ggcgtgattt
     1381 cttagtgata taaaggagaa gactagctcc tagagagacg ataaagaaat tcaaaccaaa
     1441 gaggaagctc gcaccgagaa ctaggaagag gctgatatag acacgatttt gttggtacca
     1501 gtctttagaa attgcttggg tcaagctgtc tttgcttttg aaactctcag tctgaatggc
     1561 tcggtaagag atgcgggtca gttccttgct ttccttgctg atgactagct catttgtatc
     1621 gaaatgcagt tgcaagtcct taggtaattc cttgatttga cttggaccaa tcacaacaga
     1681 aggggcttga ctagctgttc cagtataagt taatgtgcca tcgacaattg tagcatgttc
     1741 agagagatcc tggacaacct catttgtcag aggttcatag acattatcga taaaagtttc
     1801 tagcggatag gtctcctggg agctgttttg gatagcaatg ggtaccatag acaagctgat
     1861 aaggaagata ctggtaaaga gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg
     1921 cttacgaaac ccccaaatac ttgaaaaata ggaaaatgga tatggaagca taggtatctt
     1981 tctaaaaggt gttttctata tgagtattat tatatagaga aatgctcttt atttcaagtc
     2041 taggagaaaa attgcttgct acaaggatat tatttacagt gacaattgct aataatcaat
     2101 gaaaatcaaa gtgcaaacta gccacaggtt gctcaaagca caactttgag gttggagata
     2161 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgaaaaaggg tggcggggat
     2221 aaattatccc ttgtcgccac cacttgtaag tcctgaaaca aagttctttt gtaggaagaa
     2281 gaagagaata cagattggaa gggcgatgag gatagcacct gctgagaagt aggcaatctt
     2341 caagtttttc gcattgttaa cgaaggtttg gagacctacg gcaacagtaa agtattcttt
     2401 ctcacgaagc aagaaactag agaggatgta gtccccgaaa ggtcccatga aggcccagag
     2461 agcttgtacg gcaaccattg ggcgaacaag tggtagaaca atttgccaga agcggcggaa
     2521 gtgtcctgca ccgtctagtt ttgcagattc gtctaaagac attggcactg tatcgaagta
     2581 gcctttcatg agccaagcat tcatcgggat accaccacca acgtagagga agatgaggaa
     2641 ccagttgtgg ttaagggcgt tcaacataag cgccataacg aagaaggctg tcaaagcggc
     2701 catagttggc accatttgga tgatcaagaa gaagaccaaa ctttgtttac gagccaagaa
     2761 gttgtaacgg ctgtaggcat aaccagcaag tacgatgata cttgtttgaa cagccatggt
     2821 aattaaggcg ataatcaaag tgttgaggta ccaagtaccg tacaaggttt cagtgaagag
     2881 gcctttaaag ttatcaaaat tgaggtcgat attagtatct agtttaaagg ctgagacgtt
     2941 acctgcttta aaggctgaca taatggtaat caacagtgga tagataatta caattgatag
     3001 accaatcagg taaaggtaag taaggctttg agtcagtcta cgtttgagtt taattgagtt
     3061 attcatctta gacgtcctcc atatcaaatg cgtgtagttt cttgaatgcg atcatagaga
     3121 ttgagatgac aatgatagag ataatcaagg taacagctgc cgccattgag tattgaggag
     3181 atgtacctgt tgtcaaacgg tagatccatg agatcaagat atcggttgaa ccagctccac
     3241 ctccgacact accaggtcct ccaccattga agaggtacat gatagagaag ttgttaaagt
     3301 tgaaggtgta ttggctaatc aaagtaggtg ccgcaacagc caaaatcatt gggaaagtga
     3361 tgttgcggaa tttttgccaa gcgttggcac cgtcaatata agctgcttcg taaaggtcgt
     3421 taggaataga ttgcaagata cccaaagtca aaacgtagat gtatgggaat ccgagccaac
     3481 cttgcatcat aatcaaggca atcttagtcc aagttgggtc tgttttccaa ggaataagag
     3541 ctccatcaag gaaaggaagg aatttagcca agattggcaa tacttgagtg ttgatagcac
     3601 cgacactatc gttaaacatg tttgagaatg tcaagatagt gatgaaggct gggacagccc
     3661 aaggaagaag gaaaataaca ccaaagatac gttttccttt gataaatggt tggttggcaa
     3721 tgatagctgt gaagatacca attacgattt gtaaagtaga agctgccaaa gcccaaatga
     3781 tagtccaaga aagaacagaa ccaaaggcag aacggaaggt actcaagctc caaatgtttg
     3841 taaagttggt caaaccaacc cagtccaaca acttgtttgg tggcaagtgt tggaagtcgt
     3901 agttggtaaa ggcgatcatc aaggttacga taactgggaa gataatcgcg aaggtcatgg
     3961 caacataaga tggaatgatc aagaggtaag ggaagccatt ttcataaatc cctttgatca
     4021 tgtctttgag tgtgcgtgga actggaattc cattgttaat gcgttttgca atcgtatgtg
     4081 catctttgat atttgagaaa taaaagagta cataaacgat tacaaagatt agatggaagg
     4141 caccacgaat cagcataaag agggaattat cacgacctgg tttgtcacca agagtgatga
     4201 ggttgctcaa ttcaggggtt gcaagtgcta ggaagtaaag gacaaatacg atggttacac
     4261 caaggaagat aaaacctttg gctttttgtt tattgtaaat ctgtcctaac ccaggaatga
     4321 tagacagcag ggctgcttta ctaggttgtt gcttttccat attaactcct ttcataggat
     4381 actacttttt tataagaaag ctaaattatt tgtgtctcta ttgataaatt caaaggggga
     4441 tttgatttcc accccccttg aacaaatttt ttattcacca aatttttgtt tgattgtttc
     4501 tttgatcaat gttacagcat cgttagcagc tgttttagca tctttttgac cacttacagc
     4561 atcaaagagc atatttttcg ctggatccca aactgcagac atttgagaga tgtttggcag
     4621 tggttgagtg ttcttgaact gtttgataac agctgttgtc aactcatcgt ttttaccttc
     4681 agcgtatgaa cgagcctcag tattagctgg gatttcgtta gtcttatcat ataatacttt
     4741 ttgttgttca gttgcaacaa ggaagtctac aaatttttga gaagcttcaa ggttcttaac
     4801 ggcttgagga atgacccaag ctttaccacc accgaatgca gcatattctt ttccatttgg
     4861 aagagttggg atagttgcaa ctccgtagtt tactttagca tctttaaagg cttgagcttt
     4921 ccaaggtccg tcgatgatag cagctgtttt accttcttgg aattgagttt ggattaagtt
     4981 tccagcacct tctgtatctt gcataccttt aggccatttt tcgtaccaag atttagcgta
     5041 gttgatacct gcgatagaac cgtcgtttgc aagaccgatg tctttagcgt ctttaccgtt
     5101 ttggccaaag acgtaagcac cgttaccggc aagaagtcca tatgtatagt agaagtttgt
     5161 ccagtcagct aggaaggcag tagttttacc atcttcacca gcgaatgcgt atttgctatc
     5221 tttagcaagg ttttccaagt cagcaaatgt ttttggagca tctttcacca agtctttgtt
     5281 gtagtacata acaagtgact cgataacggc aggagcaccg taaactttac cattagcagc
     5341 tgttacaaga gatttagttg tgtcgtctgt tttagcacca tcgctcaatt tcacttctga
     5401 aagttgtccg tcagaaccaa ggctacctac acggtcgtat ggagccatca taacatcagg
     5461 gacattacca gattggttgt caagagaaag tttatcaaga cctcctagag catcaccagt
     5521 tttaagagtg acttttactc cagcttcttt ttcataagct ttagcaacct cttcaatata
     5581 gctcttatat ccctcgtcta catatacagt gagttctttg acttcagatg aaccagaatc
     5641 agcaggctta tcagcagttt tgcttccgca agctaccaaa agcaagctag caagtgtagc
     5701 agttccaagc accgcagtgc tcttcataaa tttagatgac atagtgtatt cctcctaaag
     5761 aatagcaagt tttattgata aggaaacgca aacgttttcc tttatgagct tagtatagca
     5821 caaatagaaa acggttgcaa gtattttttg taaaaatttt aaaaaatttt taagcttgat
     5881 ttgatagtat aattttgcat tttaatagaa gaaaagtatg aaatagataa gaatacagta
     5941 tttttaataa aaatatatgg aatctgtcta aagagggaaa tcaggagggg tacctccctg
     6001 tttctaatct atatctattt tctatagacg tttgtgcttt gttgcatata aattcaagct
     6061 ccctaaggag gttttgtact ttgtatactg tctcgtgaga gtcaaacttt aggattagat
     6121 agttttaagt tatctttgct aaaatgagtt agtctcctta aaaataatca aaaaagtttt
     6181 ttaaaaacgc ttgcaattat gcttgaaaag gagtatactt ataagtaacg caaacgtttg
     6241 cgtctgaaaa atacgcaacg ttccattatt ttaacacacg aggtgctatt atgaaaaaac
     6301 gtcaaagtgg tgtgttgatg cacatctctt ctcttccagg agcttacgga atcggatcat
     6361 ttggtcaaag tgcttacgac ttcgttgatt tcttggtccg tacaaaacaa cgttactggc
     6421 aaatccttcc attaggagca actagttacg gggattctcc ttaccaatct ttctcagcct
     6481 tcgcaggaaa cactcatttt atcgatttag atatcttggt ggagcaaggt ttgttggaag
     6541 caagtgacct tgaaggagtt gactttggta gcgatgcgtc tgaagttgac tatgctaaaa
     6601 tctactatgc acgtcgtcct cttttagaaa aagcggtgaa acgtttcttt gaagtcggag
     6661 atgttaaaga ttttgagaaa tttgctcaag acaaccaatc atggcttgag ctctttgctg
     6721 agtatatggc tatcaaagag tattttgaca atcttgcttg gactgaatgg ccagatgcag
     6781 atgctcgtgc tcgtaaagct tcagcacttg aaagctatcg tgagcaattg gcagacaagt
     6841 tggtttacca ccgtgtgact caatacttct tcttccaaca atggttgaaa ttgaaagctt
     6901 acgctaacga caaccacatc gaaatcgttg gggacatgcc aatctacgta gcggaagatt
     6961 caagtgatat gtgggcaaat ccacatctct tcaaaacaga tgtcaatggt aaggctactt
     7021 gtatcgcagg atgcccacca gatgagtttt ctgtaactgg tcagctttgg ggtaatccaa
     7081 tctatgactg ggaagcaatg gacaaagacg gctacaaatg gtggattgaa cgcttgcgtg
     7141 aaagcttcaa aatctacgat atcgttcgta tcgaccactt ccgtggcttc gaatcttact
     7201 gggaaatccc tgctggttcc gatacagcag cacctggtga gtgggtgaaa ggtccaggct
     7261 acaagctttt tgcagccgtt aaggaagaac ttggtgagct aaacatcatc gcagaagacc
     7321 ttggcttcat gacagatgaa gtgatcgaat tgcgtgaacg tactggcttc ccaggaatga
     7381 agattcttca atttgccttc aacccagaag acgaaagcat tgatagccca cacttggcac
     7441 ctgctaactc agttatgtac acaggaacac acgataacaa tacggttctt ggttggtacc
     7501 gtaatgagat tgatgatgcg actcgtgagt acatggctcg ttacacgaac cgtaaagaat
     7561 acgaaacagt ggtacacgct atgcttcgta cagtattttc atcagttagc tttatggcaa
     7621 ttgcaactat gcaagattta ctagaattgg atgaggcagc tcgtatgaac ttcccatcta
     7681 cccttggtgg aaactggtct tggcgtatga ctgaagatca attgacacca gctgtcgagg
     7741 aaggtttgct tgacttgaca acaatttatc gccgaattaa tgaaaatttg gtagatttaa
     7801 agaaataaga caataatcag gagacaacta aacatgttat cactacaaga atttgtacaa
     7861 aatcgttaca ataaaaccat tgcagaatgt agcaatgaag agctttacct tgctcttctt
     7921 aactacagca agcttgcaag cagccaaaaa ccagtcaaca ctggtaagaa aaaagtttac
     7981 tacatctcag ctgagttctt gattggtaaa ctcttgtcaa acaacttgat taaccttggt
     8041 ctttacgacg atgttaaaaa agaacttgca gctgcaggta aagacttgat cgaagttgaa
     8101 gaagttgaat tggaaccatc tcttggtaat ggtggtttgg gacgtttggc tgcctgcttt
     8161 atcgactcaa ttgctactct tggtttgaat ggtgacggtg ttggtcttaa ctaccacttt
     8221 ggtcttttcc aacaagttct taaaaacaac caacaagaaa caattccaaa tgcatggttg
     8281 acagagcaaa actggttggt tcgctcaagc cgtagctaca aagtaccatt tgcagacttt
     8341 actttgacat caactcttta cgatattgat gttactggtt atgaaacagc gactaaaaac
     8401 cgcttgcgtt tgtttgactt ggattcagtt gattcttcta ttattaaaga tggtatcaac
     8461 tttgacaaga cagatatcgc tcgcaacttg actctcttcc tttacccaga tgatagtgac
     8521 cgtcaaggtg aattgctccg tatcttccaa caatacttca tggtttcaaa cggtgcgcaa
     8581 ttgatcatcg acgaagcaat cgaaaaagga agcaacttgc atgaccttgc tgactacgca
     8641 gttgtccaaa tcaacgatac tcacccatca atggtgattc ctgaattgat tcgtcttttg
     8701 actgcacgtg gtatcgatct tgacgaagca atttcaattg ttcgtagcat gactgcctac
     8761 actaaccaca caatccttgc tgaagcgctt gaaaaatggc ctcttgaatt cttgcaagaa
     8821 gtggttcctc acttggtacc aatcatcgaa gaattggacc gtcgtgtgaa ggcagagtac
     8881 aaagatccag ctgttcaaat catcgatgag agcggacgtg ttcacatggc tcacatggat
     8941 atccactacg gatacagtgt taacggggtt gcagcactcc atactgaaat cttgaaaaat
     9001 tctgagttga aagccttcta cgacctttac ccagaaaagt tcaacaacaa aacaaacggt
     9061 atcactttcc gtcgttggct tatgcatgct aacccaagat tgtctcacta cttggatgag
     9121 attcttggag atggttggca ccatgaagca gatgagcttg aaaaactttt gtcttatgaa
     9181 gacaaagcag ctgtcaaaga aaaattggaa agcatcaagg ctcacaacaa acgtaaattg
     9241 gctcgtcact tgaaagaaca ccaaggtgtg gaaatcaatt caaattctat ctttgatatc
     9301 caaatcaaac gtcttcacga gtacaaacgc caacaaatga acgctttgta cgtaatccac
     9361 aaataccttg acatcaaagc tggtaacatc cctgctcgcc caattacaat cttctttggt
     9421 ggtaaagcag ctccagccta cacaatcgct caagatatca ttcacttgat cctttgcatg
     9481 tcagaagtta ttgctaacga tccagcagta gctccacact tgcaagtagt tatggttgaa
     9541 aactacaacg ttactgcagc aagcttcctt atcccagcat gtgatatctc agaacaaatc
     9601 tcacttgctt ctaaagaagc ttcaggtact ggtaacatga aattcatgtt gaacggagct
     9661 ttgacacttg gtactatgga cggtgctaac gtggaaatcg ctgagttggt tggagaagaa
     9721 aacatctaca tcttcggtga agattcagaa actgttatcg acctttacgc aaaagcagct
     9781 tacaaatcaa gcgaattcta cgctcgtgaa gctatcaaac cattggttga cttcatcgtt
     9841 agtgatgcag ttcttgcagc tggaaacaaa gagcgcttgg aacgtcttta caatgaattg
     9901 atcaacaaag actggttcat gactcttctt gacttggaag actacatcaa agtcaaagag
     9961 caaatgcttg ctgactacga agaccgtgac gcatggttgg ataaagtcat cgttaacatt
    10021 tctaaagcag gattcttctc atctgaccgt acaatcgctc agtataatga agacatctgg
    10081 cacttgaact aatactcttc gaaaatctct tcaaaccacg tcagctttat ctgcaacctc
    10141 aaagcggtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    10201 gtataagatg caaatttata ctaatacatt ttgtaaaaaa gcgagtttcg attgaaattc
    10261 gcttttttaa atgctgtgga tttgggtcaa tcttgtctaa aaatagggaa atcctagata
    10321 cagtgaaggc tttaaatgct ggtttttact gtcttcagcc ttatattttt tcgtagttgg
    10381 ttacctcata tctcttgtat tcgcttacat aaagtattat aatataattg taggaaagaa
    10441 ggtgttttta tgatatacac acttaaattg gtgttgttta ttacctttct tgtaataagc
    10501 ttgttacctg ataagatttt tggaaaaaat aaaaaaattt ggaaaatagt ttttgcaata
    10561 ttgacggcag tggcagcatt tatatttatg tactaagtta ttttaagaat gtagggaaat
    10621 aaaccctaca ttctttttag ttttttctgt tttctaaatt ctatttatcc aagcgcttca
    10681 acatttcttg cttcttcgct tcaagttctg cacgcttttc ttcgatttcg gcatgttttt
    10741 tctcgagttc agaacaactt gcaccattgc taaattcttt tcgccatcag gagatagggt
    10801 gagtcgacat gtctattact cacccaaagc agtcctacaa agcaggaatt ttctgttact
    10861 tttttggaaa tagtaacgtt tatacagctt tgacacttcg tatcaaagcg ccaaacacac
    10921 tccgagggat ttacagaaag cagaaaagga atgatctggt ataagatcat tccttttctc
    10981 tctttttctt taagtaatta tatacaatgt acgacgaagt cgtcattgca atgctgatcc
    11041 accacctaaa gggaacttta aacaacattg ataagataaa gaatataaac aacgaaaata
    11101 cgttataccc aattaatttt attgtatatc tcatgattaa aagttaatcc ttccgttgtt
    11161 aggaatggca tcatttttat cccataattg tgttaaataa gtccccggtg ataataaatt
    11221 catagcggat tctaaagcaa catcatttac aaaccaacta cctagatatc tagaaattgc
    11281 tgaacgaata gcactttttg ctgcatgttt tccttttact ttaattagat ttgcaaggcc
    11341 tgcagtagtt cctcctaatg ctaaagctat tgcagtatct aatagagcac ccatttgatt
    11401 aactgtaata ccttgccaag ctgctctaaa tggagagtat gtaggtggga ttgtataatc
    11461 gccttgtaat tgtcggttaa ttacttcttt gatccattgt tgtgagacgt ctggatgaaa
    11521 agattggatt tcgtttgcaa gtgtattgat ttgttcttct gttagagaag tgacaggttg
    11581 aagttccata tttgtttcaa tttgtgatac ttgttcagaa gcgtatacag ctgaaacact
    11641 tggaatcgct gatacaatta acacaattga cgtcaaaaaa accgaaataa atttcattaa
    11701 tttgttcatg agcttttctc ctttttattt gtatttgctt acattttatt atatactgtt
    11761 attatagtca agaaaaatat gctattatgt taaaaaaata tttttcaaaa tataaatgga
    11821 cggatttatt ttggattctt tttgtaattg gggcatgcct cttgacgggt aatagtagtc
    11881 ttttccccct tacccatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg
    11941 ccttatatca cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaaaattag
    12001 aactatgatt gactggctac ttttaatatt gattttggag gaagattttg tctctattat
    12061 ttattatttt aaatttatct attttgtaca agatttattc tttgagacgg gagaagtcga
    12121 aatacttgat ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat
    12181 ggttattaaa agaactgatt tcaactattt ccacttaata tgtatgaaaa ctataacaaa
    12241 acgcataaga ttaaggtttt taagcacctg ttcttatacg tttttgtaat attgaagatt
    12301 ttcggtaagt tttctacttt tgcgaagtct agtttagaat gctttcccaa ccaaaatctc
    12361 tgcttcgatg gtaatctctg tcagttggct ccagtcaatc ttgctctggt caacgtgaaa
    12421 gaggagagga gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag
    12481 agaggcagtt tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg
    12541 gttagaatac tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg
    12601 attttcagtt gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc
    12661 tccatagttg gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg
    12721 aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc
    12781 gatttggact gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc
    12841 ttgtagtttg cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt
    12901 ttttgagctt gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc
    12961 taggatttgt tgacggtttt gaaaattttc cttgtcatag ttagcagatt gcttgatttg
    13021 aggtgctaga ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt
    13081 gaaattagtc tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc
    13141 agaagcaaaa cgctgaagtt tgggcttgag atttgtattc atagtttaag tgtatcaaaa
    13201 gaggcaaatg aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta
    13261 attctccaat ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa
    13321 ggaggaaata agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc
    13381 attatttttg ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga
    13441 agctaaaaaa ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga
    13501 tgcatctgtt tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt
    13561 gtacgagcaa gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt
    13621 ttaaagtgct acatagagga taccaacata tccgactatc atcttctttt tcacttacct
    13681 tggatattca agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc
    13741 agttttacat ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag
    13801 ataatgcaga agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc
    13861 ttcccattcg tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg
    13921 tactttttcg tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt
    13981 tgggttatat tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct
    14041 tggactgttc ggctatttta ttgtccttgt ttatgaacca atccaagaca gctagcaata
    14101 tcatgtttat gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa
    14161 cagatttaga acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata
    14221 cggttgttag tataaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag
    14281 gaaatgaaat tctgtttgat gggcaagtag tttcaggttt aggtatggtc aacgaaagtt
    14341 ccttgacagg agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata
    14401 cagtattaga aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta
    14461 ttttacagct gattgagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct
    14521 atttcatcaa gatggcggat aaagtcgtca aatataattt cttgggggct gggctgactt
    14581 acctattgac aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg
    14641 ctttgaaaat ctctactcct gtagcttatt tgacagttat caaggagggg ttgaaccgtg
    14701 aaatggtgat taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt
    14761 ttgataagac aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg
    14821 gagactatag tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc
    14881 atcctattgc taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa
    14941 tgcatgggaa actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac
    15001 cagttcttat tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac
    15061 aaaatgcttt aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa
    15121 atgaattgat tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct
    15181 tggataaact taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta
    15241 ggacagagga attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg
    15301 atgggaaatt tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg
    15361 gagatggctt gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg
    15421 agagtgcaga tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt
    15481 tcttccaaga gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc
    15541 aggataccgt tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggttcagtc
    15601 cttcaaatct ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt
    15661 ctattaaaaa tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt
    15721 taactccttt gtttatagat aaatgttgaa tagtttagta agtcaataca aagtattttt
    15781 tcttcccacg acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat
    15841 agtcaaggtc ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac
    15901 gggcttggcg ttttgagtta actataccag atgagacgag cagttccacg atattgttgt
    15961 tttcgtctgc ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga
    16021 cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt
    16081 aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc
    16141 gttcgtgtgg cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga
    16201 aagtaaagat tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt
    16261 acatttcgta tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac
    16321 caaatttctt accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt
    16381 ccgccttacg acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac
    16441 cgatttgaag agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga
    16501 tttggtaagc gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct
    16561 tactcatcat gtagttgacc gtgaagtatt ttccaatatc acggaggaag tcaatgaagc
    16621 tgatgctgcc aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa
    16681 agtcaagaaa acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt
    16741 ttgtttggag actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac
    16801 cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg
    16861 cgacaaggtg gcctaggtga aggctgtcag cagttggatc gtagccagta tagtaagaaa
    16921 cttgaccttc ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac
    16981 cacgctcttt tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt
    17041 ttctacctat tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct
    17101 attttattga aaatttccct tttgtggtat aatagataaa gtgaggaaat ccatgcaaaa
    17161 tcaattaaat gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa
    17221 aaaatcagct agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa
    17281 gtcagccatt ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt
    17341 actctgtttt ctaggaggaa tgttgggagt tgggattgct ttggggtacg gagtggcctt
    17401 atttgacaag gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc
    17461 ttctatttca gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt
    17521 gttgcgcact tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc
    17581 gacagaagat gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc
    17641 gaccttgggg aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca
    17701 actaattaaa cagcaggtgg ttggggatgc gccgaccttg gctcgtaagg cggcagagat
    17761 tgtggatgct cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct
    17821 caatgtggct ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc
    17881 agctgaggga attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt
    17941 agcaggactt ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa
    18001 gagtgatgaa gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta
    18061 tcgtacaggt gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca
    18121 ggacttttta ccatcgggca cggttacagg aatttcacga gactatttat actttacaac
    18181 tttggcagaa gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc
    18241 taaggagttg aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat
    18301 tgaaaatggt ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca
    18361 aagtgcggtt gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg
    18421 gaatgtcttg atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta
    18481 tcaagaaaat caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa
    18541 gcccttgctg gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct
    18601 atctaactat ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg
    18661 aacaggaatg atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg
    18721 gacctatcgt atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg
    18781 ttacgagatt cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac
    18841 agttgcccag cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa
    18901 gcatgtgatt tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa
    18961 accggttcaa gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt
    19021 tctatcttct cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct
    19081 ggctactgca gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct
    19141 catgctttcg acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc
    19201 attgtcacgt agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc
    19261 gattcagcaa gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt
    19321 agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg
    19381 aaaagaagta gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc
    19441 gccagcgaca agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg
    19501 gtctagtatt gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc
    19561 tagcgatagc agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt
    19621 ctctaaatga agtggccaat caatggattg ccactttttt cttttcgtgt tacaataagg
    19681 gtatgaatca gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct
    19741 taatatgggg aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt
    19801 cgggctggat tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg
    19861 caatacaatt aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct
    19921 ttttagccta tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag
    19981 aatactcaaa tgctacgaca gcaactattt tacagtttat tagccctgtc tttatcctct
    20041 tttacaatcg cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg
    20101 ttgccatgct gggtgtttgc ttgatggcga caaagggaga cctctctcag ttatccatga
    20161 cgccgctagc tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct
    20221 tgccccaacc ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt
    20281 tggcaggttt gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata
    20341 tttggagtat cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca
    20401 tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg
    20461 aacctctctc ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc
    20521 tccttctagc tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga
    20581 aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg tgctatactg gaatagtcaa
    20641 taaaacacgg ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt
    20701 ttaccgacag cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa
    20761 ggtttcaaat ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca
    20821 cctatgactg ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa
    20881 aagaaaacca gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct
    20941 gttgtcaaac taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa
    21001 ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct
    21061 ttgctagata agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag
    21121 gtggaaattg gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa
    21181 atcggtgctg gaaccatgat tgacatgggt gccatccttg gtggccgtgc cattgttgga
    21241 aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct
    21301 gaaccagtcc gtgtcggaga caatgttctc atcggggcta atgcagtggt tatcgaagga
    21361 gtccaaatcg gtagtggttc agttgtcgca gcaggagcta ttgttaccca agatgtccca
    21421 gaaaacgtgg tagtagcagg tgttccagct cgtattatca aagaaattga tgcccaaact
    21481 caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga
    21541 ggcggaaccc tttttccagc ctctttctgc tatatcggag gacagataga tgttagattt
    21601 gattcagact agacgagatt tacaccagat tccagagatt ggcttggagg agttcaagac
    21661 tcaggcttat ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat
    21721 tcgtacttgg cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat
    21781 tggttggcgg acagatattg atggcctgcc tatcgtcgaa caaacaggtc taccttttgc
    21841 ttctcaacac caaggtcgca tgcatgcctg tggtcatgat tttcatatga ccattgcctt
    21901 aggctgtctt gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca
    21961 gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat gaggacgatg cttttggaga
    22021 ttggttgcca gatcaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat
    22081 tgcgactaat actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg
    22141 caaaggtggc cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta
    22201 ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt
    22261 ggtgaccttc ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt
    22321 tttacatgga actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt
    22381 aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa
    22441 acaaggtgga tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt
    22501 ctttgacgag aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga
    22561 ctttggttat ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc
    22621 ctacgctctt catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc
    22681 tgcggtgtct agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg
    22741 gaattacgca agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct
    22801 atagaccaag ctttaaccga gcggctttta caccatccct tctaccaaga agccaaggtc
    22861 atcgcaacct acctctcttt ttctcatgag tttcaaacgc gggaactgat tgagcaggcg
    22921 ctgaaggacg gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggagttt
    22981 gtggcctatg atccgcaaca gttggtaaaa acttcctttg ccttactgga gccacaggga
    23041 gatgtggaag tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt
    23101 acgacgaaag gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat
    23161 ttttctggtc gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa
    23221 aaccatgata ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta
    23281 ccctgtgacg agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac
    23341 tgcaggcgga aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc
    23401 agctattcgc ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat
    23461 tgggtgggaa catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga
    23521 ggagattttc ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa
    23581 tctctttgtt tttgtattta gtcctaaatc cttagcagca ggcgcctcta cctctcttta
    23641 tgggctattt gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atatccaaca
    23701 gctagggcaa tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc
    23761 aggaatcagc ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat
    23821 ctttccagtt agaggagaaa aacggatgta taacaccagc cagagattag gagcggtagt
    23881 cttgttcgta ggactcgcca ttttgctttt ctacaaggga atgggaatgt gacgaagttg
    23941 aaagaaaatt tgtgtaatga aaaaagataa ggcatttttt gaaccttatc tttttatttt
    24001 attccttctc agtcaattct tttccaagtt ggatgaggta attcttcaaa tcatctttga
    24061 cttgtggatg tttgagggcg tagtcaatag atgttttcat aaagccaaac ttatccccaa
    24121 cgtcgtaacg agctcctgta aattcacggg caaaaacacg ctgtgtttta ttaagagtat
    24181 cgattgcatc agtaagttgg atttcatttc cagcaccagg agcttggttt tcgaggattt
    24241 ggaaaatttc aggcgtgagg aggtagcgtc cgataatagc aaggtcgcta ggagcgtcct
    24301 ctggagctgg tttttcaaca aaggtttcaa cactgtaaag accatctttt ccttcgcctt
    24361 gcggagcaat aaccccgtaa gcagatactt cgtcatgagg gactggcatg acagcgatag
    24421 tagacgcgtg ggtacgcttg tagtcatcca tgagttgttt ggtaagtgga acagcctttt
    24481 cgtctgtgat atccatcaag tcatcaccaa gcataacgac aaaaggttca tttccgacga
    24541 aagccttggc ttgcaaaaca gcatctccga gaccgcgtgg atgagtttgg cggataaaat
    24601 gcagacgcat gccagttgtt tcatcaacta gcttcaaaag atctgttttc cctttttctt
    24661 tgaggttata ttccaattcg aagtttgaat cgaagtggtc ctcaatagaa cgttttgatt
    24721 taccagtgac aactagaata tcttcaatac ctgatttgag agcctcttcc acgataaact
    24781 ggatagttgg tttgtctacg attggcaaca tttctttggc aagggccttg gttgctggta
    24841 aaaatcgagt tcctagtcca gcagcaggga taactgcctt tctaactttt gatgtcataa
    24901 aaatcctttc tatagagggt taagaccact cattttctgc tttaaattca ttgttcatga
    24961 tgtcataaat ggcatctttg atattggttc cgtgataaat aacttggtaa atagcctgtg
    25021 taatgggcat atagactcca agttcttggg ctagttcata ggctgctcga gtcgttgaaa
    25081 ttccttcgat taccatgccc atattagctt ctatatcagc tagggattct cctcgtccga
    25141 gagcatctcc agctctccag ttacgagagt ggatggaagt tcccgttacg atcaaatctc
    25201 ccacaccaga taagccgcta taggtcaatg gactggcccc gagtgctacc cctaggcggg
    25261 tgatttctgc taaacctcga gcgatgatgg ctgccttagc attatcacca aatccaagac
    25321 catgtaaagc tccagcaccg acagcaataa tatttttaag agcaccagca gtttcaaccc
    25381 cgataacatc cgtattggta taaagtcgga agtagtgatt actaaatagc tcctgaacgt
    25441 attgagctgt ttgtaaatct ttagaagcag cagttattaa agttaggtca cgcacaatgg
    25501 tctcttctgc atgactaggc cctgaaacaa cgacgatatc actacggaga tgttcaggaa
    25561 tttcttcttc aagaatggtt gataatcgtt tatggctatc aggttctaat ccctttgatg
    25621 cgtgcatgat gataacctta tggtccaagg tttgtgcaac ttgctgggca acaagtcgtg
    25681 tcacttttgt tgggacaaca aacaaaatcg catccacatt tttcaatgtt tctgctaagt
    25741 cggtgtaggc aatgatattt tcgtctagaa cgacatcttt aaagtagtgc ttattagtat
    25801 ggtgtgtatt aatttcattg atttgctcgg gaagatttcc ccaaatacgt acctcgtgtc
    25861 cattgtcatt taagacttgt gaaagggcgg ttccccaaga accaggcccc aagacggcga
    25921 cggtttgttt ttccatgatt tcctccttga tagatttctt tctcttattc tatcatattc
    25981 taggggattt tgcacttgca ttactggggt atggtggaaa aatacacaaa gaccgagatg
    26041 aagggataaa ctcttagtct ttagttaaag tgagaagaaa tctgatagat agtttgattc
    26101 agtatatgct tataatagag gtaaacaact caggaagttc ttgtaggttg cgagagtttg
    26161 gcgaaaaaat taaaagatta cgtttggcta aaaaaatcag tcgttcagaa ttttgtggtg
    26221 atgagtctga attaagtatc cgtcaattaa ttagaattga aaatggagaa tccagaccaa
    26281 cactaacaaa gttaaaatat attgctgaac gtttggaggt tgaagattac aagttgatgc
    26341 caagttatat agagttggat aaggaatacc tagaattgaa gtatttcttg atgaggactc
    26401 ctacatacga agatgaaact atcgcccaaa agaaagagag tgtttttgat aagatttttg
    26461 aagagtatta tgataggcta cctgaggaag aaagatttat catcccaaat tattcatatc
    26521 tagcactagc gaactacaca gttcaaaaat taccagaaaa gctagttgaa atactgtcct
    26581 tctggtgatt ttgcttaatt tctgatgttc gagacatgat tgaggagatt tgtcttgatt
    26641 ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc tcgattttta aaataaggtg
    26701 acttattctg ttaggcagtt ttcccctgcc ctctagctct atatggaaca gggagtatca
    26761 gatttatctg gcagattgta tcaaataagg cttgaaactg ttttgaatag gcgtatagac
    26821 ttgagaattt gagaatatgt cgtctagcag tagagacata ttttccggca atatgaagga
    26881 agagacgtcg aaaacgcttg atagtcaagg cctttacttc atcaccagct agctgcttta
    26941 aaaagaggta gagattataa gccagacagc ccatcatcat acgtacttca ttcttaatca
    27001 tggtcgaact atctgtctta tccccaaaga atcctgcttt cctttctttg ataaagtttt
    27061 cagcattccc tcgttcacga tagaattgaa acagctcctc actatctaca ctgcttaaat
    27121 tggtcaaatg aactttttta caaccataaa aaagagcact taatcgtact cttctctttt
    27181 aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta gactaggcgt
    27241 tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat ataaaggtat
    27301 tgagttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat ttcctttgat
    27361 aaggcataat aatattggtc aatctgttca tctttttgag caatactaat agcttttgag
    27421 gcttggtgca aaggaaaggc aaccaataaa tcggctagca tgctgaggga taatttaccc
    27481 atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg caaaacagct
    27541 ttggcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga agacatgatg
    27601 ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa acgggcacag
    27661 gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat aattagctct
    27721 gccatctcct tgtctttgga ggctaaggcc agtaaggctt ttgaagctgt ttcaaggaca
    27781 agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc aaattgattt
    27841 ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct gtgcgctgat
    27901 cttttggatt ggtaaacacg tcaacggtat ctccaaattc gcaaatttct cctgttaaga
    27961 aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta acaatgataa
    28021 tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg gagatagggt
    28081 ctaaggctga agtcggctca tccattaaca gaatatcagg ttctactgct aaagctcgcg
    28141 caatgcaaag gcgttgctgc tgaccgccag ataaggacat agcactcttt ttaagatcat
    28201 ctttgacttc ttcccaaatg gctgcccctt ttaaagattt ctccactaag gcatctaatt
    28261 gttttttgtc tcgaatacca tgtgtccttg ggccataagc cacgttatca tagatagaca
    28321 tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttacgtagc tgattaaggt
    28381 tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca atatggcaag
    28441 aaggaaccaa atcgttcatc cggttaaggg tttttagaaa agttgatttg ccacaaccag
    28501 atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata ttttttaagg
    28561 cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc atactaggaa
    28621 gctcctttca caagttttcg agataataag cttgatagag tatttatcat taaaacagta
    28681 ataatcaaaa tcacaccggt agcataggct tcattgacat gtagcccctc acttgacagc
    28741 atatacatat gcagggctag agaacgacct gaagacatga gactacttgg cgtattggta
    28801 gaggtaccta atgtatacat gagggcagct gtctcaccaa cgatacggcc aatagctagt
    28861 atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa aacagtccgt
    28921 aacttacctg ccccaagtcc ataacttgct tgacgcatga tatcactaac agataaaagg
    28981 gcttcttctg ttgagcgaat aatgactggc aacaccatga tgactgaggt taagattcct
    29041 gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc aaacagacca
    29101 aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcatgat tttaacacaa
    29161 agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc tatgggcaag
    29221 gctaaaagaa gagcaccaaa gaccagaata acggtggaaa taatcgctgg cataagggaa
    29281 atgttctcag aagtataagt ccaagaaaag agggatagac ttagatgagg taagcctttg
    29341 atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga aaaacaataa
    29401 acgagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt aggcaaagta
    29461 ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa gggcttccct
    29521 atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg ttctggttcc
    29581 tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa ctgccatggt
    29641 ttcacctact gcgcgaccga ttcctaaaat aactgctgat aaaataccag atctcgcagc
    29701 tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca agctaccaga
    29761 ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa tggttggcaa
    29821 aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc ctaaaaagct
    29881 tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag atggaatggc
    29941 cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac aataataaac
    30001 cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc ctaaggtaat
    30061 taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt tcgttggcga
    30121 ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag gtaagccatt
    30181 actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg cactcatgaa
    30241 aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt atcacatctt gtcctttcta
    30301 gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct tattgtacga
    30361 tgaaacgtct gcatctcttt agagatttat ggagcaaaca ttttatttaa tcttgtccca
    30421 ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt ggcttgcctt
    30481 attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat gggtgagact
    30541 cttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg ttttctcctt
    30601 aacagcggta atacctgctg aagacccatt agaggtaata tcaatcgtaa cttctggatt
    30661 ttctttttta taagcttctg ctaatttttc cattaaagaa gatactgaag tggaacctac
    30721 aacagacaac ttgcctgata agtgttggct tgtatattct gtggtttcag ttttagcttc
    30781 aataaattta ttatctgtga ccacttgttg accttgtttg gagtggataa agctgataaa
    30841 atcttgacct agcttggaaa gattagaaga ccaaacaatg ttgaagggac gttgaagagg
    30901 gtattcacca tctaaaactg tgtctcgact agccttgaca ccatcaatct ctaaagcctt
    30961 gacagatttc gttaaagatc ccaaggagat gtagccgata gcattagcat tcccttgaac
    31021 tgctgagaga acaccttctg tactattttg aatcacagct gttttggcag tgttgtcaat
    31081 ttttttatca ccgtcttttt tgagaatccc tgtgatttct gtgaaggcac cccgtgttcc
    31141 agagccattt tctcgtgaaa tcacctcaat cgttcctgaa gctgactgtt tggaagcagc
    31201 tgactgattg ccacaggcaa caagcccaaa tcctgataag ccaatggctg caagagtaag
    31261 catttttttg aatttcataa taatcacctt tatctctatg tatttttctt gtgtaggctt
    31321 actacattta tagtctaaca agtctttgta aaggtttatc cctgattcat gtaaagattg
    31381 tgtaaagaat caaaaaaagc cacttttgaa aaatggctgc tcctaaaaat agctttaaaa
    31441 attattagtc ctgtgcgaaa gattggttag gaagaaaaat cgtgaagcaa ctgcctctgc
    31501 caagctgact tgtcaccgtg acttggccac ctaataattg actgagttct ttgacaatgg
    31561 caaggccaag accagtgcca ccagtttgtc tgcttcgacc tttattaact cggtaaaaac
    31621 gttcaaaaat acgatcctgc tctaattgac taataccaat ccctgtatct gatacagaaa
    31681 tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat ttttccccct tgttcagtgt
    31741 aacggatggc attggataaa agattgagta agatttggga aagtaattga ctatctgata
    31801 cgagggtgac atcatctggc acctgcacct ttagctgtaa atccttcttc ttgagctgag
    31861 gttgcaagct ttgagtcaaa tcctgtacaa attctgccaa agaaagggtc gtccattgta
    31921 taggcatttg ttgagcctta gataaggtaa gaagatgctc aacaatatgc tcaagacgca
    31981 agctttcttt gtaaataatg tctagaaagt catccttgag cgcttcttct tcagcagaca
    32041 tccccttaat ggtttcagca aagcccttaa tcgaagtaac tggtgtcctc aattcatggg
    32101 aggcatttga gacaaaggct aaatttaact tttcataagt tctaatcgtt gttaaatcat
    32161 atagcaagac gagcacagct tccacagatt gggtggggct aaaaacggga actgctgtca
    32221 cttctaaaat caagtcaccc tcatgaaacc cacttacttc ttgttttaac cttgtttttt
    32281 gatcaaaggc ttggtgaact aaatttcgaa tatccatccg tttgaggtca tcaagtgaac
    32341 ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga gcgactggat aataacatct
    32401 gaccttgagc ggaaactaaa aacgtcccca tggttaggtg cgacagaaga acctccattg
    32461 tttcggctag gtccttgtat tgctgatcct gttgggagac tttggttttt aggccagaca
    32521 catactgagc caaagacttt aagtcttctt gccctttttc taaaaagtat tcactactgg
    32581 tcaagagagg ttggtgcaag gtctcaaaag caacttccca tttccaaagg caaaagagcc
    32641 agtagccacc ttgtcccaaa gaaagggcta gaagaaagag accgatgcct ttactgatcc
    32701 aagttaatgc catccctgca atcagaatga ggctaacact tagattgact agccaaaatt
    32761 gaaggtagcg tttcatctat aactccttga acttataacc ataaccccga atggttcgaa
    32821 taaattgagg ggctttagga ttgtcttcaa ttttttccct caacttacca atatgaacgt
    32881 ccaccaaacg tgtttcctgc ccaaagtcat acccccagat acgttccaaa agacgctctc
    32941 tagtcagtgt catgttggga tgtttcataa gatagagcaa gagttcaaat tcttttgggg
    33001 tcaaactcag taacttattc gccttgtaga cttcatgacg ctcagggtat actttcaagg
    33061 tcccaaatag ccaagaatcg tcagcgatat tatctgaatc atctccttct tgttctcctt
    33121 tagttcgcct gaggacagcc ttgacacgcg ccagcaattc tctagggcta aaaggcttgg
    33181 tcaggtagtc atcagcccct aattccaagg ccaaaacctt atcaaattca tcacttttcg
    33241 cagaaaccat cataattgga gttttgacgc ctttggctct cagccgctta caaacttcca
    33301 tgccatctaa ttgtggtaac atgatatcaa gcaagataaa atcaaagggt tctgtttctg
    33361 ccaaagctaa ggccttccgt ccatttgtta ccaattgagt agaaaagcct tccttactta
    33421 aatggtagtc aagcaatttc agaatgtgtt cttcatcatc cactaataag acttgttttg
    33481 tcatctatta tctcctattg gtaacattat aacacaatta tcagaaatcc taacattgct
    33541 aaatcagatt aaatttgcct atcaagacta gtatctggtc aaacgctcaa tcatctcctt
    33601 gtgctctgga taggtcgcca gtagatctac cctttcaaat aattcaaaat cctcaaattc
    33661 aaaaccagga gcaacaagac aagaaaccag agcatcatcc ttatcaactg ttgatcccca
    33721 aatagtgccc ttaggaacac agtagtgaag ttgttgccct ttggatatgt ccaggcctaa
    33781 agtgactgct tcgtagtgac catctgctgt aatcatgtga acagtaagtg gggatcctgc
    33841 atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa tgtgaaggat tcgtttcttc
    33901 taataagaaa taaatactgg tataaagcgc ccttccctta ccagcaaggt ttatagtgtc
    33961 tgaagctttt tttgtttgtc taaaatagcc accttcaaca tggggagcta actctagagt
    34021 tcttatcaag tcttctttat ccgtcggagc caatgggttg aagtaactct tgttcaaagt
    34081 ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
    34141 gaagtaaaaa tcaatcgccc taaaaaaaga attagcgaat tattctggta aaaagaaatg
    34201 ccacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat
    34261 cgctgtgaac tattgtcatg atatgaagtt gttcaaaatg agttgcagaa atatcg
//
LOCUS       DBERAE010000019        33681 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.19, whole genome shotgun sequence.
ACCESSION   DBERAE010000019 DBERAE010000000
VERSION     DBERAE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.19"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(417..1397)
                     /locus_tag="ACL70N_001095"
     CDS             complement(417..1397)
                     /locus_tag="ACL70N_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGS0589904.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1713..3728)
                     /gene="recG"
                     /locus_tag="ACL70N_001096"
     CDS             complement(1713..3728)
                     /gene="recG"
                     /locus_tag="ACL70N_001096"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGS0589905.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIVKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3747..4850)
                     /gene="alr"
                     /locus_tag="ACL70N_001097"
     CDS             complement(3747..4850)
                     /gene="alr"
                     /locus_tag="ACL70N_001097"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGS0589906.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4840..5202)
                     /gene="acpS"
                     /locus_tag="ACL70N_001098"
     CDS             complement(4840..5202)
                     /gene="acpS"
                     /locus_tag="ACL70N_001098"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGS0589907.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5247..6278)
                     /locus_tag="ACL70N_001099"
     CDS             complement(5247..6278)
                     /locus_tag="ACL70N_001099"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS0589908.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMELENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6280..7311)
                     /locus_tag="ACL70N_001100"
     CDS             complement(6280..7311)
                     /locus_tag="ACL70N_001100"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS0589909.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7392..9905)
                     /gene="secA"
                     /locus_tag="ACL70N_001101"
     CDS             complement(7392..9905)
                     /gene="secA"
                     /locus_tag="ACL70N_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGS0589910.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10051..10338)
                     /locus_tag="ACL70N_001102"
     CDS             complement(10051..10338)
                     /locus_tag="ACL70N_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589911.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10349..10999)
                     /locus_tag="ACL70N_001103"
     CDS             complement(10349..10999)
                     /locus_tag="ACL70N_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589912.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGNNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISKDISDLCTDVLAVENGHIQYVKDIQS"
     gene            complement(11003..11644)
                     /locus_tag="ACL70N_001104"
     CDS             complement(11003..11644)
                     /locus_tag="ACL70N_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589913.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11637..12428)
                     /locus_tag="ACL70N_001105"
     CDS             complement(11637..12428)
                     /locus_tag="ACL70N_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589914.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12613..12948)
                     /locus_tag="ACL70N_001106"
     CDS             complement(12613..12948)
                     /locus_tag="ACL70N_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589915.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNVADIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13088..13423)
                     /locus_tag="ACL70N_001107"
     CDS             complement(13088..13423)
                     /locus_tag="ACL70N_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589916.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13514..14824)
                     /gene="der"
                     /locus_tag="ACL70N_001108"
     CDS             complement(13514..14824)
                     /gene="der"
                     /locus_tag="ACL70N_001108"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGS0589917.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14838..15551)
                     /locus_tag="ACL70N_001109"
     CDS             complement(14838..15551)
                     /locus_tag="ACL70N_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGS0589918.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15548..16444)
                     /gene="dnaI"
                     /locus_tag="ACL70N_001110"
     CDS             complement(15548..16444)
                     /gene="dnaI"
                     /locus_tag="ACL70N_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGS0589919.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16445..17614)
                     /locus_tag="ACL70N_001111"
     CDS             complement(16445..17614)
                     /locus_tag="ACL70N_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS0589920.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(17615..18088)
                     /gene="nrdR"
                     /locus_tag="ACL70N_001112"
     CDS             complement(17615..18088)
                     /gene="nrdR"
                     /locus_tag="ACL70N_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGS0589921.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18228..18593
                     /locus_tag="ACL70N_001113"
     CDS             18228..18593
                     /locus_tag="ACL70N_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0589922.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18598..19293
                     /locus_tag="ACL70N_001114"
     CDS             18598..19293
                     /locus_tag="ACL70N_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589923.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19310..20077
                     /locus_tag="ACL70N_001115"
     CDS             19310..20077
                     /locus_tag="ACL70N_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589924.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20430..21629)
                     /locus_tag="ACL70N_001116"
     CDS             complement(20430..21629)
                     /locus_tag="ACL70N_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0589925.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21626..22519)
                     /locus_tag="ACL70N_001117"
     CDS             complement(21626..22519)
                     /locus_tag="ACL70N_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0589926.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22641..22832
                     /locus_tag="ACL70N_001118"
     CDS             22641..22832
                     /locus_tag="ACL70N_001118"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589927.1"
                     /translation="MKSKERTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23200..23413
                     /locus_tag="ACL70N_001119"
                     /pseudo
     CDS             23200..23413
                     /locus_tag="ACL70N_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23828..24445
                     /locus_tag="ACL70N_001120"
     CDS             23828..24445
                     /locus_tag="ACL70N_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGS0589928.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24765..25652)
                     /gene="scrK"
                     /locus_tag="ACL70N_001121"
     CDS             complement(24765..25652)
                     /gene="scrK"
                     /locus_tag="ACL70N_001121"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGS0589929.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25801..27684)
                     /locus_tag="ACL70N_001122"
     CDS             complement(25801..27684)
                     /locus_tag="ACL70N_001122"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGS0589930.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            28061..29515
                     /locus_tag="ACL70N_001123"
     CDS             28061..29515
                     /locus_tag="ACL70N_001123"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGS0589931.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29496..30461
                     /locus_tag="ACL70N_001124"
     CDS             29496..30461
                     /locus_tag="ACL70N_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0589932.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30496..31770)
                     /locus_tag="ACL70N_001125"
     CDS             complement(30496..31770)
                     /locus_tag="ACL70N_001125"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGS0589933.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31770..32942)
                     /locus_tag="ACL70N_001126"
     CDS             complement(31770..32942)
                     /locus_tag="ACL70N_001126"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGS0589934.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33073..33321)
                     /locus_tag="ACL70N_001127"
     CDS             complement(33073..33321)
                     /locus_tag="ACL70N_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0589935.1"
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33389..>33681)
                     /locus_tag="ACL70N_001128"
     CDS             complement(33389..>33681)
                     /locus_tag="ACL70N_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS0589936.1"
                     /translation="RNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKAC
                     NHALSKERSKVENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         9870 a         7511 c         6381 g         9919 t
ORIGIN      
        1 gttttgaggt tgtggataga actgacgaag tcagtaacca tacctacggc aaggcgaagc
       61 tgacgtggtt tgaagagatt tttgaaaagt attaacacct acagacaagc ctaacgatag
      121 caagaactac cctactcgat aggtatcggc ttttgctttc tgaaaaaaat tattttaagc
      181 aatttgacaa atctagcaac aaaaaattct ataaatataa tagattgaaa ctagaatagt
      241 acacatctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
      301 attcttgttt cattttacta tatttccatg ataaaacgca tagtatcaag tttttttaat
      361 cccctgatac tatgcgtgtt tgtaattttt aagattttgt gcttagagtc gactccttat
      421 tttagatatt taaaaggaat ctcacttcca cagagccagt tgtagacttg gtcattgaca
      481 aatacattca tggcttcgtg agcatactca ggcatgatac gataggtttt atcgcaggtc
      541 agacgattat aaatcgcaaa ctgggtaatg ggatagcaaa catcgtcgtc caagcccgta
      601 atcatcttaa cctcaccttg gatacgatgg gcaagatttt tgacatcgat ataggcaagg
      661 gtcgccatga tttcctcctc tgtttcatgg aaggggtcgt gaaacttgaa ataacggaaa
      721 agttcgtcgt aagcctcgct agtattacca atctcaatca cccgtctgaa gtctgacaag
      781 aagggataaa tggcaactgt tttctgaatt cgaggattga gcgctgctgc aactagagct
      841 agagcccctc cttgtgaggc accatagcta gaaagacgct tctcatcaac ctgagacaga
      901 ctagcaacaa tttcgaccaa ctggtaaata tccagataaa catccttata aaagaggtgg
      961 tcccgacctt ccatagcacc acggataata tgccccttca cggtatttcc taaaggagaa
     1021 cgcaagccgt cttgtgagta acctgactgg ccccgcacat ccatggaaac aacaccataa
     1081 ccagctacgg tgaagcccag catgtcggcc cagtcccagc cacgtcccat ataaccatga
     1141 aaatggaaga ttagtggaac cttctcctca ctctttggaa gaacaatgcg tgcatagacc
     1201 tttccttcct tgcttccttc aaatgttaac tcatagcact tgacttgagg aatgtggaaa
     1261 tctctttcct ccaagtggta ggatggaggt gtggaaacat ttttcacttc cccatcccag
     1321 aaagcatcaa agtcttccgg aacctcatcc cttcctctat aggtcttaat ttcttctagc
     1381 aaagctggat ttttcatagc atgctccttt tattttgtaa tcgttaccac aactgtagca
     1441 tatctatgta atcaatgcaa gaaagaagga taaatagaaa gtgaatttag attctttact
     1501 tttaggatga tgggctgaaa gtagttttag aaacgaaaaa gagcatttcg ctctctcttc
     1561 tgtttatact agttttttgc ttccttcttt tggaaagtgg tttggtaatt tactttaatc
     1621 gttactgtca tatgagagtc ctcgtttctt tttgatgact ttagtataag agccaaacct
     1681 aaaaactagc ttaagttttc cttagagaaa gcttaatcca gatgttcttt cttttccaga
     1741 tgaagggcaa tcatgcgcca ctctggatct tcttgccaag cttctataga actaatgtag
     1801 ctagcaacct ttcttgcttc ttctaaaatc ggaaaatctt cgataatatc agccacttgg
     1861 aactctggaa gtcctgactg tctggttcca aaaatctcac cagaaccacg cattttcaaa
     1921 tcttcctccg caaggacaaa tccattggtc gtttctgtca tgatgcgcat gcggtctttc
     1981 ccagaatccg tcttgggatt ggcaacgaga acagcgtagg actgcttgtc cccccgaccg
     2041 acacgacctc taagctggtg aagttgactg agaccgaagc gatcggcatc catgataatc
     2101 atgacagtcg cattgggaac gttgacccca acctcaataa ccgtcgtcga aaccagaata
     2161 tccgtctttc tctccttgaa atcctgcatg atctggtctt tttcgtcact cttcatccta
     2221 ccatgtagaa gagccacctc tgccttgcct gcaaaatgag tcgtcaactc ctctgataag
     2281 gcaatggcat ttttcaaatc tagagcttct gattcttcaa tcaaaggaga gatgacatag
     2341 gcttgggaac ctttttgaat ttccccctct aaccaagtca agacctgagg tagttgctca
     2401 tgtttgatcc agcgcgtcac aataggcttc cgacctgctg gcatctggtc gataatggaa
     2461 acatccatat ctccaaaggc tgtgatggca agcgtccgtg gaatgggagt cgccgtcatc
     2521 atgaggacat ctggattgtc acctttttcc cgtaaaatac gcctttgccc tacaccaaaa
     2581 cggtgctgct catcgataat aatcaaacca agacgagcat actccacccc atcttgtatc
     2641 agagcgtgag ttcctataat caaatcagcc tcacccttga caatggtctc caagacttct
     2701 ctcttttctg cagctttcaa ggaacctgtc aagagagcca gtttcaaatt gggaaaaagg
     2761 ttctgtaaac tctcaaagtg ttgctctgcg aggatttctg ttggtaccat tagggcagcc
     2821 tgataacctg ctgtcactgc cgcaaacatg gccaagccag cgactaccgt ttttccactc
     2881 cccacatctc cttgtaggag acgattcatg tggtggtcgg acttcatatc agttaaaatt
     2941 tcctgcaaac tcttttcctg agcttgggtc agggcaaaag gaagacttgc tttaactgct
     3001 gtcacttttt cctgagacca atccagaacc agaccacttc cctgaactct attttcagac
     3061 ttgagcgtct gcagctgcat ttggaaataa aagagttcct caaacttgat acggcgaaga
     3121 gcctgcttgt attctgccaa atcctttgga aaatgcatag ctcggactgc ctgacaacgg
     3181 gacatgagtt tgtatttgtc tagtaaagac tggggcagat tttcttctat caagaggtcc
     3241 agtccctgat caaaagccgt cttgatgacc ttgaccagac tggcctgact gattccctga
     3301 gccagacgat agacaggctg gaggtcatct tctacctgag ccagaacctt catcccagtc
     3361 agactagcct tagcgcggtc ccattttcca aagacagcaa gggttgctcc caactctatt
     3421 ttatcagcca gatagggctg gttaaagaaa ttcaccgcaa aaacgacctc tccctgcttg
     3481 agactaaaac gcaggcgatt gcgcttgaaa ccataatact ggacactagc aggagtcact
     3541 acctgaccag aaagaactgc cttctcaccg tcttccagct ccagcacctg cttggttttg
     3601 aagtcttcat aacggaaagg aaagtagagc aagagatctt gcaagttttc aattcctagt
     3661 ttggcgtatt tttctgctga ctttggtccc acaccaggca agacatgcaa gggttgatgt
     3721 agattcatgc tccactcctt tcttttctaa taatattctc tcggaatacg gtcgctgagg
     3781 aggcaaacca cctcatagtt aatggttacg cggtaggtcg ctacctgagt tgcagtgatt
     3841 tccttatccc cattggagcc aatcaaggtt accttggttc ctagcggata aagcttaggc
     3901 aatcgaatag tgatttggtc catcgaaacc ctgccgacaa ttgggcaagc ttggccatct
     3961 accaagacag agaaattttg catgtctctt gtccatccat ctgcataccc gattggcacg
     4021 gtcgcgatga cttgctcgct atccgcttga taagttgctc catagcccat gcaagctcca
     4081 gctggaactg tcttgacatg aaccagagca gactccaagg tcaaggccgg tatcaaatca
     4141 taaggcaaat ccaagaccgc tccacttgga ttgaggccat acatggcatc tcccatacga
     4201 accgcattga aaatagtctc tacatgccaa agagtcgttg cagaattgct agcatgaacc
     4261 agctctggaa cttccttcat actagctaaa atagttttaa accgttctaa ctgggcatta
     4321 aaatagtcat ctgattcctc atcagcagta gcaaagtggg taaagattcc ttcaacacga
     4381 acaccgtgtt gttgtagcaa atcttgagcc tgctcaacct cactggcctc tctaaaacca
     4441 atccgtccca tccctgaatc aatcttgagg tggactgtca atccagttag gtccacttcc
     4501 ttatctaaga gtgcttgaat ccactccagt ccagccactg tcaaggtgaa gtcatattct
     4561 ttagctagag caacagcttc gatttcagaa actcctaaaa tgaggattgg cttgctgagt
     4621 ccagcttgtc tgagttcaat ggcttcatcg atattggaaa cgcaaaagcc atcaacatca
     4681 tcttgaattg ccttggcaac ggcaacagct ccatgaccat aagcattggc cttgaccaca
     4741 gccaacttga gcgttccttg agggatatga gcccccattt gctgaatatt ttgtcgaata
     4801 gctcccagat gaatcagagc cttggttggt ctatgtggac tagctttcat gattttcctc
     4861 caaaatgaca ctggctgtca caaactgatc ggtgtggctg atagacagcc aaatctttcc
     4921 tgaaaatggt gcctgactaa aataaggcgc cccacgttca ttgttcaaga cttccaaatc
     4981 ctgaaaaccg agcttgctaa tgcccgttcc catagccttg gaaaaggcct ccttagccga
     5041 ccagcgacca gctaaatatt ctatttgcct gcgtcctttg agactggtga agcgctccat
     5101 ttcctgagcg gtcagtacac gcttagcaaa tccttcatgt cgtgtaactg cgctttctat
     5161 cgaagccaat tcttcgatgt caattccgtg tccaactatc attctcatca aaaggagttg
     5221 agattcccca actccatcct tttcacttat tttgtcaagg taacataaat ctcttctacc
     5281 aaggcctctg tattttccca acctaggcaa gggtcagtaa tagagcaacc aaagacctct
     5341 ggttggtttt gacgaccatc tgctaggtaa gattcaatca taaatcctcg aaccgtcttt
     5401 ttaattttct cattccaatc acgattctgc aaggtctggc gaacaattcg aatctgctcc
     5461 atatattgct tgcctgagtt atcatggttg gtgtcaatga ggataaaagg attttcaagt
     5521 tccatggttt catagcgttc aatggcttgg agtaggtttt catagtagta attcggcata
     5581 taattgccat actcgttgac tgctccacgg aggataacat gggccaaagg attacctgat
     5641 gtctcaactt cctgcccatg ataaaggaag gtttgcttgt tttgagcagc atagatggcg
     5701 ttaaacataa cacccaaatt tcctgaggtt ggatttttca tccctactgg tgcatcaatc
     5761 ccagaagcca caaagcggtg ctcttggtct tccacagaac gagctccaac ggcatggtag
     5821 ctgaccaagt catccaccaa gatcagattt gacggataaa gcatctcatc tgccgttgtc
     5881 aaaccagtct ctgtaatcac gcggtagtgc aactggcgca cagcctgcaa gccgttaatc
     5941 aggcttggag ccttagaagt atctggctgg tgaaccaatc ctttatagcc gtctccattg
     6001 gtacgaggct tagcagtata cacgcgcatg accatgaaaa tcttgtccgc taccttcttt
     6061 tgcaaggcgg ataaacggcg agcatattcc aagaccgcct cttcattatc agaagagcaa
     6121 ggaccaatca ccaagagaat acggtcatct tcccctgaaa taatatctgc caattccctg
     6181 tcacggcttt ccttgagtct caaggcttcc gcagacaatt gggtttcagc cttgatgact
     6241 tccatatcga tttcttgacc tttttcaata aatgccatct tattctccta acgttttgta
     6301 aatttctctg acaagagctt ctgtgttatc ccaacccagg caagggtctg tgatagactt
     6361 accaaatact tctggctcat tttgtcgacc atcttccaga taagactcaa tcataaaacc
     6421 acgaacgaac tgcttaattt tttcattcca agcacggtta atcaaggtct ggcggacaat
     6481 tcggatctgt tcaatatact gcttaccaga attgtcatga ttggtatcaa tgatgataaa
     6541 aggattttcc aagcccattt tctcatactg ggcaatggta tcaattaaat tgtcataata
     6601 gtagttggga atattttttc catactcatt aagagcacca cgaagaatag cgtgtgaaag
     6661 cgggttccca gttgtttcta cttcttttcc taagaaaagg aaactttgtt tgttttgagc
     6721 agcataaatc ccattaaaca tgacattgag atttccagag gttggatttt taaaaccagt
     6781 agaaaatcct gccccacttg ccacaaagcg gtgttgctgg tcttcaactg aacgggcacc
     6841 aactgccatg taagaaatca aatcatctac aagcggaagg ttttcaggat aaagcatttc
     6901 atcagcagtt gtcatccctg tttctgtgat gacacgatag tgaagatggc gaacggcttt
     6961 gattccattg ataagactag gcgcttctgt cgcgttaggc tggtgaatca agcccttata
     7021 gccatctccg ttggtacggg gtttggcagt ataaacacgc ataaccataa agatacgatc
     7081 tgccacttct tcttgtagga ctgccaaacg cttagcgtat tcaaggacag cttcttcgtt
     7141 gtcagatgag catggcccga ttaccaagag aattcgctgg tcttctccac gtataatggc
     7201 ttctagctct tgatctcgct gtgatttcct ctccaaagcc tgaccttcta attttgacaa
     7261 ggcacgaact tcttctatat ttattttaga gctttttgct gtaaatacca taactcatct
     7321 ccttataaag caaacggata cccagtaaaa atttactttt cacaagatat ccgcctctaa
     7381 actatctcat tttattgtct tttaccgtga cagtttttaa atttcttacc agaaccacat
     7441 gggcaaagtt cattgcgtcc aatctggctc aaatccaaat cttctggcat acttgcttgg
     7501 tgagcagcga tattgcgagt cgctgttgta ctgatatgac gttctgcctg tggtctttct
     7561 tgttcatgaa tttgtgcttt catcatcaag cgtgtcacat caaactcaat cgaaccaatc
     7621 atatcattaa acatacggaa accttctgcc tgatactcaa caacagggtt gttctgagca
     7681 tagccacgaa gtccaaccgc gttacgcaat tgatcaaggg catcgatatg atctgtccac
     7741 ttgttatcca ccactcgtag aatcaaaact ttttggaatt ctttaactgc ttcttcatcg
     7801 cgtagttttg aaacctgact atcgtaaacc ttcaaggcac gttggaaaag ctcttccttg
     7861 atggccttat cagacaagcc tgacaagtct tccatcgtaa tagaatcttc aggaagcaag
     7921 ttgtacttag caaagttcaa aattgcctct agtttttcat cttgtttggc acgcgcatga
     7981 ccatcaacga cacgttcaat cgtgcgtttg atcatagact gaatttcagg tgccaagtca
     8041 cgatctgcag tgatgacatc gtaacgttga gcatagataa tctcacgttg ttcacgcatg
     8101 acatcatcgt attgaaggac ttgtttacgg gtatcgtagt tatttccttc gacacgtttc
     8161 tgagctgctt caacctgacg cgtcaacatg cgagactcaa tcgcctcttc agacatgttc
     8221 aagcgttcaa agattccctt caagcgttca gaaccaaaac gtttcatcaa atcatcttca
     8281 agagataggt agaattgtga ctcacctgga tctccttgac gacctgaacg tccacgaagc
     8341 tggttatcga tacgacgact ttcatgacgt tctgtaccaa taacacaaag tcctccaagt
     8401 tcacgaacac cttcaccaag cttgatgtcg gtaccacgac ccgccatgtt ggttgcgatg
     8461 gtaacggcac cacgttgacc agcattcatg atgatttggg cttctctata gtggtttttg
     8521 gcattcaaga cttcgtgagg aacaccagct gcaaccaatt tcttagaaat gtagtcacta
     8581 gtttcaaccg ctactgtacc aaccaagaca ggttgaccct tttggtaacg agccttaacg
     8641 tcttcgacaa ccgctttaaa cttagattct atacttgcat aaagaaggtc tgagtggtca
     8701 atacgttgaa caggacggtt tgttgggatt ggaataacac gaatgttgta gatttcacgg
     8761 aattcttctt cctcagtctt acctgtaccc gtcataccag acaatttctt gtacatacgg
     8821 aaaaggtttt ggtacgtgat tgaggcagat gtcttggttt catcctggat tggcacacct
     8881 tctttggctt caatagcttg gtgcaatcca tcagaataac gacgaccttc catggtacga
     8941 cctgtaaatt ggtcgacaat caagatttct tgctcttcgc tcaccacata gtcaatatcg
     9001 agaagcatga tgtagttggc acgaagggcg ttatcgataa agtgggtcaa agccacgttt
     9061 tcgatgtcat agaggttttc aagtttgaag tagctttcag ccctgtcaat ccctgaatca
     9121 gacaaaccaa tagtcttaga ctgcacatcg atgatgtagt catctttgtt caaagatttt
     9181 acatagtggt ctgccatgtg atacaactga ctggtttcaa ccgcattggc acctgataca
     9241 atcaaaggtg tacgagcctc gtcaatcaag atagagtcaa cctcatcgac caaggcatag
     9301 ttaagcggac gttgtaccat gttttcagcg cgaacgacca tattgtcacg aaggtagtca
     9361 aatccgattt ctgagttagt tgagtaagta atatcacact cataggcttc ttttttctcc
     9421 attggagatt tggtagccaa gttaatccct actgacaaac caagccaaga gtacaattca
     9481 cccatctcag tcgcgtcacg ttctgacagg tattcattaa ccgtaactac gtgaacccct
     9541 ttacctgaaa gggcattgag gtataccggc atggtcgcag tcaaggtttt cccttcccct
     9601 gtacgcatct ctggcacgtc accatggtga agaacaatcc cccccatgac ctgaacctta
     9661 taagggaaga gacctaggac acgtttggca ccttcacgga caaccgcaaa tgcttcgtaa
     9721 agcaatgaat ccagtgattc tccattttga taacgttcct taaattcaac tgtttttgct
     9781 tttagttggt cgtcagtcaa agcagccatt tggtcttcgt atttgaaaac cttgtcagcc
     9841 atcttttcca gacgacggat ttctccttta tcattttcga taattgtttt taaaatatta
     9901 gccatgtttt tccttacttt aaattccgaa tattttagaa tgttccttta attttagcac
     9961 aattactgat tattttcaag gaagaatccc cattttgaaa aggaaaaaga ggttagtttt
    10021 caagctaacc tctccgactt ttatgatgct ttaattgcca aaaatcggca aaatggcaaa
    10081 tgtgataaat aagttaatcc aaagagaaag acagcaaatc agtccaaaaa caaagagact
    10141 gactttcttg gacagcaagg ccatcaaaat ggacagaatt ccaaaagcta gcaagatttt
    10201 ctgtatgatg aagatgtcaa tccttacccc cagaatcgct ctatcccaag ggataaagaa
    10261 gaaagtcagc cagatcagca gaactaaacc aatataaacc ttggaatagc gtgtaataaa
    10321 tgattttaga tgtgccataa gccatctcct aggattgtat atcctttaca tattgtatat
    10381 gtccattttc gacagctaat acatctgtac aaaggtctga aatatctttc gatatgtgcg
    10441 acgtcaggat aaccagacca ttttcttttt tcaggtaaga taaaatgacc tgtttggtta
    10501 acctcacact cttctcatcc aaagcattca taggttcatc gagaaagagt atagaaggag
    10561 aggaaataaa ggcttgaatc aaggccattt tttgctttgt tcccaaggat aaatgacggt
    10621 attcaacgtc ttcaaattcc tgtaaatcat agtattgaat ccaataggca attctttttt
    10681 ccgtaacttt agatgaaaaa taccttaaca gttccaaatt ttctctcagg gataaatgag
    10741 ataaaaactc gactttttca attaaaattc ctgcatcctg aatataatga ttttttaccc
    10801 cgtaaacttt accatcttga agaacttttc ctttgtcaag cttaatataa ccagcaagta
    10861 tctttaaaag aaccgtcttg ccagatccat tattaccttt aagtccataa atttttcctg
    10921 attgaaacac caaattcaac tgatttaaaa taggtctttt cccataaatt ttctgtccat
    10981 ttataatttc aagtctcatc gtttatcctt tcttaaattt ctcttccaag cgactaagaa
    11041 tcaacataac taataagctt aagagtacta aatacactgt tacaatatga tccatcatcc
    11101 attcttgtcc cacaaatgcc aaaaaataga gaaaaaaaga aaaaccagcg cccgcactaa
    11161 tcagtgctat cagataagac agtagtaagt acaacatcat taactgagca agtaaaaaga
    11221 aaagtgcgac tgttttgaaa tgaattccta gaggaagtaa accaagaaac cagacaaaca
    11281 aatcttgagt aaaaaattta gaaatgacaa ccaatcgttt ccttgtataa tcgaaaaagg
    11341 agcttgattg atagcgaatc aagtgatggt aatggtctgc caaatcactt tcaagtaaaa
    11401 tgacagagag ccatcctacc atgaaaagcg aaaggtttaa caagagtttg gggatttcta
    11461 aattcacttc agaatagtca ttataggaaa aaattgaaat caattctctc ttgaaaaaga
    11521 taacagcatc ctgcttttga accgctgttg acaatagatg gtttatcaaa atcatcatca
    11581 gaactatacg aagtagtaaa acaatctttc tctttagcaa aatattgtta aaattcttaa
    11641 acattatctt catatttttc aagcaccatg taagggacaa tataaaggat ataaggagta
    11701 aagagtttca tcaaacttac atccccatag ctagcttgca tcaaactcgt cataggaacc
    11761 atatagtaag gcaaggcact atagagcagc atagaaccaa gccaaagaaa catcaaatag
    11821 gtgattgccg aacgagtcac atttcctaaa taatcaacta tttgtaaaaa atagactgca
    11881 ttgatgaaaa taccgattag taggacacaa gtaaagaaca aatagcttgt tatctctcca
    11941 tctaggagcc tttgtaaact actcccatca gaaaatagag aattccatcc aagaggagaa
    12001 aaagtcccaa agaaatgagt taaaattgca attatcagca cagtcactaa atatatcaaa
    12061 caagggatac ttgcaacttg caaagtcaac tttcttttta acccttgata actcacttct
    12121 cttccaatac tcaatcgtaa aactttattt ttcagctcaa tatattgaaa acctagcaaa
    12181 acaatgatga ttggaataat aaatgattga taaaaaccta gattgaactg gagaatacga
    12241 aaatctaatg ctgattttaa taagtcattt ttaattgctt gtccatcgaa tttagctaga
    12301 tcgggcgcat gaatatcaaa aaagaaataa gtcatcaaaa catcacgata aaccaaagca
    12361 agaaaaagca aagtaagcaa gacataaaca aatttatgcc ttgccaaagt taagagagga
    12421 atcttcataa gccacctcct acaaatagaa agtaatataa tactcaatga aaatcaaaga
    12481 gcaaactagg aaactagccg caagttgctc aaagcactgc tttgaggttg tagataagac
    12541 tgacgaagtc agttacatat ataatccaag gcgacgttga cgtggtttga agagattttc
    12601 gaagagtata aatcaatgcc ttccgccttt agacttccct agttcccgtc tcaagtcaag
    12661 catttttttg aaacagatat agtctaacca gtcactagca aaagcgataa gtagtaataa
    12721 tagccaaata ccccataact tgatgtctgc cacatttctc aagacgatat tgaaaaacag
    12781 aactgaaaaa actgtccaag caaggctaaa aagagcatag agggtgatgt aaatccagta
    12841 aaaatagtaa aaaattggga aaaatttact ttctctatta tccttgtcaa tccagctgaa
    12901 aaagtaaaaa cagggtaata agattatcat tttaaacaag tgttccatca caagcctcct
    12961 tttttaaatt gttttcttta gtttcgttct attaaatgtt attaccaata taaaccttgg
    13021 aatagcgtgt aataaatgat tttagaggta ccataagcca cctcctacaa atagaaaccg
    13081 atataaatca atgccttcca cccttagact tccctagttc ctgtctcaag cgaaacattt
    13141 ctttgaaaca ggaataagtt aaccaattca taccaatagc tagcagaata aaaagaaacc
    13201 aaatgcccca taacttgata tctgtcacat ttctcaagac ggtattgaaa aacagaactg
    13261 aaacaactgt ccaagcaagg ctaaaaagag aatagaaggg gatgtaaaac cagtaaaaat
    13321 aataaaaaat tggaaaaaac ttactatttc tgttggcctt ctcaatccag ttatcaaaat
    13381 aaaagtacgg tgctaaaagt aagaatttaa acaaatgttc catcaccgac atcaccctcc
    13441 ttcttttgat agcgttttct attattttat tatatcaaaa aaatccggaa ctgtcattcc
    13501 agattctact tttttatttg cgttttcttg cgatgagatg aatcggtgtt ccctcaaaaa
    13561 caaaggcctt gcggatttga ttttccaaga aacgcaggta agaaaagtgc atgagttctt
    13621 cttcattgac aaagatgaca aaggttggtg gtttggttgc cacttgggtc gcatagaaaa
    13681 tcttgagacg ttttcctttg tctgtcggtg ttgggttgat ggcaatggca tccatgatga
    13741 catcgttcaa gacagctgat ggaatacgtg tattttgact ttcgctgatt tgcttaatca
    13801 tctcaggaag tttgtggaga cgttgcttgg ttaaagctga tacaaagata atcggtgcgt
    13861 aaggcaggta ttggaactgc tcacggatat cttcttccca gtttttcata gtgtggttat
    13921 ctttttcaag cgtatcccac ttgttgacca cgataatcat ccctttacca gcttcatggg
    13981 caaatcctgc gatacgcttg tcgtactcac gaatgccttc ttccgcattg atgaccatca
    14041 agaccacatc tgaacggtca atagcacgca tggcacgcat aacagagtat ttctcagtat
    14101 tttcataaac cttaccagac ttacgcatac cagccgtatc aatcatggta aactcttgac
    14161 catctgtatc tgtaaagtgg gtatcaatgg catcacgagt tgttccagca acaggactag
    14221 caataacacg gtcttctccc aagatagcat tgatcaagct tgattttcca acgttaggac
    14281 gaccaatcaa gctaaactta atgacatctg gattttcttc ctcatattca tttggaagat
    14341 tttctacgat cgcatctagc acatcccctg taccgattcc atggacagat gagataggca
    14401 atggttcacc caaaccgaga gcatagaaat catagatatc atttctcatc tcagggttgt
    14461 ccaccttgtt gactgcgagg ataactggtt tgtgggtctt ataaagctta cgagctacgt
    14521 attcgtctgc atcagtaatt ccttccttac cagacacgac aaaaacgata acatctgctt
    14581 cttccatggc aatttctgcc tggtgcttga tttgttccat gaaaggagca tcgacatcat
    14641 caattcctcc tgtatcaatc atgctaaaag aacgattgag ccactcaccc gttgcataaa
    14701 tacggtcacg tgtcactcct tcgacatctt ctacaatgga gattcgctca ccagcgatcc
    14761 gattaaatag ggttgatttc ccaacattgg gacgtcctac aatggcaata gttggtaggg
    14821 ccataatttc tcactttcta caataatttc ttctgttcaa gattttttct agttgagctt
    14881 ggttcagctt gaccaaactg ttctgctagg cgctgactcc agcttgtggt cgcacgcgcc
    14941 ccagcatagt cagcctgaac acggtcataa gcttggattg cctcagttga ctgttcttgg
    15001 tattcttcct caaagacaac attctctagt ggcagtcttg gtttcatatc atgatgttga
    15061 tttggcacac ccagtgccat cccaaagaca gaataggtgt agtcaggtag gttaaagagc
    15121 tctgccactt cttcagactt gtatcgaacc aaaccgataa tcacaccacc atagcccaag
    15181 ctttcagctg ccaacaaggc gttttgtcca gcaagagctg catcgaccga actaatcaag
    15241 agaccttcca caccttgggg ttggaaggtg tcggtatgaa gtcgggctcc cttttctgct
    15301 cggttcaaat ctccgacaaa gagaaggaaa acagcagact ggcgaatggc ttcttgaggt
    15361 accaattcat acaaggcatc tttcttctct tgacttcgta ccacaatcac agagtaggat
    15421 tggaaattct tccaagatga tgccatctgg gctgctgtca aaatctcatt taagtctact
    15481 tggggaattt cttgctcttt aaacctgcgc actgaagtat gagccttcat caatttaatg
    15541 gtttctgtca tcgacggttt actccttcta aacgagtctc ctcagccaaa taacggatgc
    15601 gttccatgac ccgtctggct tcccaggttt cgtcatttcc atgtttcact ttcgcaaaat
    15661 gcttctccaa atcttcaaag ttgaagttgg atgtgaaaaa ggtcggtaaa ttttcctgca
    15721 tccgatattg gagaatgacc tgcaggattt cgtcacgcac ccaaacggtt gattgctcgg
    15781 cgccaatatc atctaaaatc aggacctcag acagcttaat ctcatccacc aaggtcttaa
    15841 cattgccatc actgatagca tttttgacat caatgacaaa gctaggatag tggaggagag
    15901 tggatgatac accacgtttt tctgataaat catgagctag ggcagccacc atgaaacttt
    15961 tacccacacc aaagtctcca tacaagtaaa gacctttcaa attattgggg taatcgttaa
    16021 caaattctat cattcttttt agaacagtta agcgctgaac atcatcacga taaacatcta
    16081 aaaaactgac atttttcagg ctagatggaa aattaattaa gttgagacgt ttcttgatag
    16141 ccgcttcttt ttcagctgcg attagttcag gagtttcttc ataagaaaca tctgcatagc
    16201 catggttcat gactaatata ggcttgtagc ctttggcaat ataatctgta tctcctcgga
    16261 ggaatttatc tctctcagtg atgtattggt taaacttgga aatactacgg ttcaactcgt
    16321 cctgattgag ggattcttgc tggacaaagg ccgcaacatc aggatccttc atgattttct
    16381 gaactaaatc ttgatagtga aaacgacttg gttgacgttt gagtacatct ccgacacttt
    16441 ccatctaatc acctccgtta tctaattttg ctaataattc tagggtttgg cgttccatct
    16501 cttctaattc ctcagcggat gacgtatttt tatattcagg attactccat ttaggaatat
    16561 tggtttttgc tggggcagtc tgattctgtt tttgtgtttt tgctttctgt tctcgctcac
    16621 ggatgcgcaa gactgccttt tctgccgaat gaatcttttg ataggcatag tcattggcta
    16681 ccttcatggc atatttctca ttgatatttg ccgaatcgac cttattaaag gtcaataaaa
    16741 gaatgatatt gatgacttcg tccagcaagc ccaagccagc catctgttgc aagagttctc
    16801 tttctgtttg ggtaatggtt cccttgcgtg tttgcttgat ttctgccaag aactgcaggg
    16861 cagttttact tttggcttct ttgataatgg ttgtttcctt aagactaaag tcagaggaaa
    16921 ctggtttttg agcaattttt tcccgcatgc gtttggttga aataacctga gaaacagctg
    16981 ttgacttggc caattgatag gtttcaaacc aagtccattt cttctcctcg gcaatagcaa
    17041 agaggtttaa gacatcggac tgctcatccg caaaacgaag tccatctcga gccatcagct
    17101 ggcgaaaatg gtccaagtca aaatcgttgg ccactttctt cttgagacca aggtcttctt
    17161 gactgcctag ttctgccaat tctggaaaga cttgattgag tgagacaggt atttcttcac
    17221 catcagcact ttcaactttc aaatcctcca cagctacatc gccaatcttt ttctctaaga
    17281 gtctgcgata aacaggatgc tccaagaagt cttgactaga tagaggagca tggaggacta
    17341 gctgataaac atcccccttt tgatagaggg tcaagagatt aaaagcagat aagattttca
    17401 atgattttat cagtctatcc atcccaaagt taagatggtt gagaatgctt gaaaaaagat
    17461 attcctttct accattatcc caaaaactga ttgtataaag ataaaggctc agtgcctcct
    17521 gaccgataat cgggaggtag cactgtacca gagatgaggt atcttgcgac acccgattat
    17581 tctttagata agaaaaacgg tcaattggct tcatttatct ttcctttttc tttttagagg
    17641 actgggtgat ttgttggagc aagctctcta actcactgac atccttaaaa ctacgataga
    17701 cactagcaaa acgtacatag gtaatctcgt ccaattcagc caactcctcc atgacgagtg
    17761 aaccaatgtc ctcactttga atttcatttt catttcgacc acggagtttc tgttcgatac
    17821 gattgactac catgttgatt tcatcacttg acacaggacg tttctgggct gagcggataa
    17881 tcccattaaa gattttatct ctggagaatt gttcccgtgt gccatctttt ttaacaacca
    17941 ctaaggttct ttcttctact cgttcgtagg ttgtaaaacg gtgttggcat tcgtcgcact
    18001 cacgtcttct acgaatggtg ttcccttctt ctgcttggcg actatcgata acacttgact
    18061 tggtagcccc acattttgga caacgcatcc tttccctcct tatcgttttc ttttcattat
    18121 accatttttt aagcgattcc caaaacaatt cttctttttg cttgacaagt tttttgtttt
    18181 gttgtattat ttaattaaga caaaagggta aaagaaagga gactaagatg tcctggacat
    18241 ttgacaacaa aaaacccatc tatttacaga ttatggagaa aatcaagctt cagattgttt
    18301 cccatacact ggaacccaat caacaacttc caaccgtgag ggagctagct agcgaggctg
    18361 gtgtcaatcc caataccatc caaagagcct tatcagacct tgaacgagaa ggatttgtct
    18421 acagcaagcg aacaactgga cgatttgtga ctaaggataa ggagctaatc gctcagtcac
    18481 gcaaacaatt atcagaagaa gaattggaac acttcgtttc ctccatgacc cattttggct
    18541 atgaaaaaga agaactacca ggcgtagtca gtgattatat taaaggagtt taagcctatg
    18601 tcattactag catttgaaaa tgtatccaaa tcatatggag caacaccagc ccttgaaaat
    18661 gtttctcttg acattccagc tggaaaaatt gtcggccttc ttgggccaaa cggctcagga
    18721 aaaacaaccc tgattaaact aattaatggc ctcttacaac cagatcaagg acgtgtcctc
    18781 atcaacgaca tggacccaag cccagcaacc aaggccgttg tagcttattt gcctgatacg
    18841 acctatctca atgagcaaat gaaggtcaaa gaagccctaa cctacttcaa gaccttctat
    18901 aaagatttca atcttgaacg cgcccatcat ctacttgcag acctgggcat tgatgaaaat
    18961 agtcgtctca agaaactatc aaaaggaaac aaagaaaagg ttcaactgat tttggttatg
    19021 agccgtgatg ctcgtctcta tgttttggat gaacccattg gtggggtgga tccagcagcc
    19081 cgtgcttata tcctcaatac cattatcaac aactactcac caacttctac cgttttgatt
    19141 tctacccact tgatttctga tatcgagcca atcttggatg aaattgtctt cctaaaagac
    19201 ggaaaagtcg tccgtcaagg aaatgtagat gatattcgct acgagtcagg tgaatccatt
    19261 gaccaactct tccgtcagga atttaaggcc taagcaaagg agattattta tgttttggaa
    19321 tttagttcac tacgaattta aaaatgttaa caagtggtat ttagccctct acgcagccgt
    19381 gctagtcctt tctgccctca tcggaataca gacacaaggc tttaaaaatc taccttacca
    19441 agaaagtcag gctactatgc tactttttct agctacagtc tttggtggct tgatgcttac
    19501 acttgcgatt tcaaccattt tcttgattat taaacgcttc aaaggtagtg tctacgaccg
    19561 acaaggctat ctgactttga ccttgccagt ttctgaacac catatcatca cagccaaact
    19621 aatcggtgcc tttatctggt cattgattag caccgctgta ttggctctaa gtgctgttat
    19681 tattctggct ttaacagctc cagaatggat tcctctttct tatgtgatta catttgtaga
    19741 aacacatctc cctcagatct ttcttacagg tatatccttc ctactaaata ccatttcagg
    19801 aatcctctgc atctacctgg ctatttccat tggacagctt ttcaatgaat accgtacagc
    19861 actcgctgtt gcagcctaca ttggtatcca aatcgtcatt ggatttattg aacttttctt
    19921 caatcttagt tccaatttct atgtcaattc actggtagga ctcaatgacc atttctatat
    19981 gggagcaggt atagccattg ttaaagaact catattcata gctatctttt atctcggaac
    20041 ctactacatc ttgagaaata aggttaattt gctttaaata atttttacct agatatgtaa
    20101 catactcata gaacaaaaga gaccaggcaa aaagtcttta aaattagaaa acgcatagta
    20161 tcaagtgtta aaaatccttg atattatgcg ttttttgtga gctgacttat ttcctttcgc
    20221 tatatcgcaa aatgaaataa gaacggaacg atgggatttt ggaattcaaa tcaatttata
    20281 agaatgtttt agaagtaata ttatcctatt ccagattcag ttcactatac aattgagttt
    20341 tcaagcaacc tgtttacata atgtgtacat aattaggttc gtgattccac ccttttcacc
    20401 tttaaaaacc tcgctttcgc aaggctcttc tatttataag ataaggcacg tttaaaggtt
    20461 ttccaaatcc ctaaatcatc cgtttgaaga acgagactag catacatgcg tccgataaat
    20521 cctgttgcta ccaccgcaaa aatcactgta atagcaagtg aaatccatgc ttctgctccc
    20581 cccgcatagc cattaatcgt tcgaaacggc ataaagaagg tcgaaataaa gggaatataa
    20641 gaaccaatct tcaagaggag attgtcacca gctgcaccta gagctgtcac tccaaaaaaa
    20701 ccacccataa tcaaaatcat caaaggcgac aaggctttcc ctgagtcctc aggacgagaa
    20761 accatagatc ctaggaaggc tgccaagact acgtacatga aaagactgat caaaataaag
    20821 agcaaggtat tcagtgagat agcatctccc aagtgatcca aaataccaga ctgagccaag
    20881 aatggcaaat ctttaaagag caaaacggca gccagaccac ctacaacata gatcccaata
    20941 tgcgttaaaa tcactagaaa cagagccatc atccgcgcat agaaatagtg acttgccctt
    21001 atgctagaaa aaacgacttc cataattttg gtgccttttt cactggcaac ttcctgagct
    21061 gttacacccg cataggtaat cagaatcata taaagaaaga atcctaaggc acctgctgca
    21121 attgtttgaa taaacttttt attttccttg gcttcatcaa tcttttctgt gaattgaatt
    21181 gtctgcgcta agcgtttttc ctgctcttga gacaaggaag cagttgaacg attaagctga
    21241 ttttgcagtt cattgagtgt acctgtaacc tcaaatttaa ttccattttc aagcgatgtt
    21301 tcgccatgat aaactgcctt tagaacacta tcttcttgat caatggtcaa ataacctttt
    21361 aatttttctt ctttaattgc ttctttggca cttgcttcgt ctttatagtc gaagttaaca
    21421 ccatttacat tcttcagtcc ttctgctaca gatggcactg ttgtcactac tgccacttta
    21481 ttatttttag ccatagaaga accttggata tgcccaattc ctacagagat tcctaaaaag
    21541 aggaacggcg aaatcaccat aaagaagaaa ctccatgact cgacatgtcg aagataggtt
    21601 tccttgatta caacccacat atttctcata cttccactcc tgattctagt ttaaagattt
    21661 catcgatagt tggcgcttgt tggtcaaatg ttgcgatata ttgaccttga gtcaagattg
    21721 ggaagagttc ccttccagcg ctctcatcct ccaaaatcaa tttccaactg ccttgtttgg
    21781 tcaagctcac ctgtttgaca tgaggaagat tttccaattc ttccttgctt cgttcacttg
    21841 aaacaaagag acgcgttttc ccgtattgat tgcggacatc ctgaactggt ccgtgcaaga
    21901 ccacacggcc atctcggatc atcagaatat cgtcacaaag ttcctcaaca ttggtcatga
    21961 catggtcaga aaagataatg gttgctccgc gctctttttc ctgaaaaatg acttgtttga
    22021 gcaattctgt attaactggg tccaatccac taaaaggctc atccaagata atcaggtctg
    22081 gttcatgaat cagagtaata atgagctgaa tcttctgctg atttcctttt gacagactct
    22141 tgattttatc tgtcagcttt cctttcactt ccaacctctt catccattga gggagttttt
    22201 ctttgacttc tttggcatcc atgcctttta gagtcgccaa gtagcgaact tgttcaagaa
    22261 ctgtcaattt aggcatgaga ctgcgttctt caggcagata accaatccga gcataggtct
    22321 cctgacgaat atcctgacca tccagaccga tttctccctg atattctagg aatttcaaaa
    22381 tactatggaa aatcgttgtt tttccagcac cattttttcc gactagtccc aaaatacgac
    22441 ctggtcgcgc ttgaaagtca ataccaaaca aaacttgctt ggagccaaaa cttttctcta
    22501 gacttcttac ttctagcatc tttcacctcc gaaatttctt gcactcatta tactcctttt
    22561 tgatagcctt tacaatgttt ttgtccattt ttagaagact attgctgtgt aaaatatggc
    22621 ctggagcact tttatactca atgaaaagca aagagcgaac taggaagcta gccgtaggct
    22681 gctcaaagta cagctttgag gttgcagata aaactgacga agtcagctca aaacactgtt
    22741 ttgaggttgt ggatagaact gacgaagtca gtaactatat ctacggcaag gcgaagctaa
    22801 cgtggtttga agagattttc gaagagtatt agtgataaat ccattataca gtagcaaact
    22861 caatttatac cttccgctcc tcaactgtct atttttaatc ctgaattgtt atttgagtaa
    22921 ctcctttttc ctcataaagt tttcttcctc taaaacttct ggaaaaaagc gaatagtttc
    22981 agacaacatt tttataagaa acaagttcat ctgtcatttc aagaaggagt aatcctttat
    23041 ctactaatgg acggaacgga attcaaccgc ttgtccgata tattttctaa ggattatata
    23101 gtaaaatgaa ataaaaacag gacaaataga tcgggacagt caaatcgatt tctaacaatg
    23161 ttttagaagt agatgtatac tattctagtt tcaatctgct atatctatta tgcacaccac
    23221 tataggatct aataaaaatc acaacaagtt cattcataga tggttacctc agggaactaa
    23281 gaaaacgact acaaaggaag tcgcattcat cgaaaagtgg attaacaact atcctaaaaa
    23341 atgcttgaac tacaagtccc ccagagaaga cttctggatg actaacttga acttgaaatt
    23401 tagcaataat taattcacca tctaactata tttagtaatt atttcagaac tgattaatat
    23461 taaaattaac taacaattca aaggattcat actagccata aattacgtcc atcagagaga
    23521 gactcttact acttttagat tttagtcttt ctagcttcag aatacatcta aactttaggg
    23581 aaaatgacta ttcgaaagcg cgaatgcctc aaaattatct cagataagct attcgaaact
    23641 tagaatgctt ttaaatttat ggaattgcga ttattcgaaa cctagaatgc atataacctt
    23701 tagttgacag acctattcta agtctcgaag ggctatttac tttctattcc ttatcaaaaa
    23761 agactcattc cccctttctc ctccaaaata tggtatagta gaaatatact atctatgagg
    23821 agtttacatg tcacaggata aacaaatgaa agctgtttct ccccttctgc agcgagttat
    23881 caatatctca tcgattgtcg gtggggttgg gagtttgatt ttctgtattt gggcttatca
    23941 ggctgggatt ttacaatcca aggaaaccct ctctgccttt atccagcagg caggcatctg
    24001 gggtccacct ctctttatct ttttacagat tttacagact gtcgtcccta tcattccagg
    24061 ggccttgacc tcggtggctg gggtctttat ctacgggcac atcatcggga ctatctacaa
    24121 ctatatcggc atcgtgattg gctgtgccat tatcttttat ctagtgcgcc tatacggagc
    24181 tgcctttgtc cagtctgtcg tcagcaagcg cacctacgac aagtacatcg gctggctaga
    24241 taagggcaat cgttttgacc gcttctttat ttttatgatg atttggccca ttagcccagc
    24301 tgactttctc tgtatgctgg ctgccctgac caagatgagt ttcaagcgct acatgaccat
    24361 catcattctg accaaaccct ttaccctcgt ggtttatacc tacggtttga cctatattat
    24421 tgactttttc tggcaaatgc tttgacacgt aaaaaatccg tttggtttcc caagtggatt
    24481 tttaaagcgt agattaacta tagcttgata ctaaatatac tttggtatgg aaattatgca
    24541 tatttttcga tagtgaggcg aggacttacc tagcctttcc gccgtgatag aaacacctga
    24601 aatctaatgg tttcaggtat tcggaaactt tgagacacta ggctcaaagt ttaggtatgg
    24661 aatttcgaag aaagtcgcta ccgtccgtaa tcacttaagg aaaggctcaa aaatattgtt
    24721 ttcaaccaca aaatccgttt ggtttcccaa gcggattttg tgctttattt tgaaacttct
    24781 tttgcaagaa caaagttccc aagtgtggca gaaccatttc ctgcgactgc tggcgtcacg
    24841 atatagtcac gcacatctgg tactggtagg taaccattaa gaagagatgt aaatttctca
    24901 cggacacggt ccagcatatg ttgttgagcc atgacccctc caccaaagac aatcacgtct
    24961 gggcggaaag tcactgtcgc attaaccgca gcttgagcga tatagtaggc ttgaacatcc
    25021 caaacagggt tgttgagttc aatattttcc ccacgtacac ctgtacgagc ttccaaactt
    25081 ggaccagctg cataaccttc tagacatccc ttatggaaag gacaaacacc cttaaactct
    25141 ttttcaatat ccattgggtg tctagcaaca taataatgac ccatttcagg gtgacccaca
    25201 ccaccgataa actcaccacg ttggatgacg cctgcaccga tacctgtacc gattgtgtag
    25261 taaaccaagt tttcgatacg accaccagca ttgttacggg caaccatttc accgtaagca
    25321 gagctgttta cgtctgttgt gaagtacatt ggcacgttta gggcgcgacg aagggcacca
    25381 agcaagtcta catttgccca gtttggtttt ggagtcgtcg tgataaagcc ataagttttt
    25441 gagtttttgt caatatcaat cggcccaaat gaaccaactg caagaccagc aaggttatcg
    25501 aattttgaga agaactcaat ggttttatcg attgtttcga ttggagttgt tgttggaaat
    25561 tgtgtttttt ctacaacgtt aaagttttca tcaccgacag cacagacaaa ctttgtaccg
    25621 cccgcttcca agcttccata taattttgtc atgataaacc tcttgttttt attttcttta
    25681 ttatagcata cttcgaaagt ctaaatgtct ctatttttta gattttcctc tgtaaatctt
    25741 actatctaat aaaaacgaac aaacatgtca tttgttcgtt ttcacattag agaggattga
    25801 ttagattttc acttcgatca cagcatcccc cttcgaaact gaacctgttg cgactggagc
    25861 tactgaagcg tagtcagctg tatttgtaac gataaccatt gttgtatcat caagtccagc
    25921 tgcagcgatt ttgtttgagt caaatgttcc aagaacatcg ccagctttca ccttattacc
    25981 ttgagcaact tttgcttcaa aaccgtcacc gttcatagat acagtgtcaa taccaacgtg
    26041 aatcaaaact tcagcaccat ttcttgtttt caaaccaaaa gcgtgccctg ttggaaaggc
    26101 aattgaaact tcagcatcag ctagtgcata gaccacgcct tgacttggtt tcacagcgat
    26161 accttgtccc atagctccac ttgagaagac tgggtcattg acatcagcaa gagcgacaac
    26221 atcaccgacg ataggagtta caagtgtttc attttgaaga gctgctggcg caacttcttc
    26281 tttttcttca gccacttcag cttgttttgc agctgcagtt gcgtctactt catcttcgta
    26341 accaaacatg taagtaagag caaaaccaag ggcaaatgat acagctacca taagaaggta
    26401 ttgtggaagt tgtccgttac caacataaag cattgtacca gggatgatgg tgataccatt
    26461 accagtacca gcaagtccaa ggatagaagc caatccacca ccgattgcac cagcaatcaa
    26521 tgaaaggaag aatggtttac ggaagcgcaa gttcaccccg aagatagcag gctctgtaat
    26581 acctaggaag gcagaaagag cagccgggaa agcaagtgtt ttcagttttg gattttttgt
    26641 tttaacacca accgcaacag tagcagcacc ttgagctgtc atagcagctg tgatgatagc
    26701 gttgaatggg ttagcatggt cagcagcaag taattgcact tcaagcaagt tgaagatgtg
    26761 gtgcacacct gacacgacga tcaattggtg aaccccacca atcaagaaac caccaagacc
    26821 aaatggcatg ctaagaatcg cttttgtagc aataaggatg tagttttcaa caacgtggaa
    26881 aactggtcca atgacaaaga gtccaaggat agacatgacc aaaagtgtca cgaatggtgt
    26941 taccaagagg tcaatgacat ctggaacaac cttgcggaca gctttttcaa atttagctcc
    27001 gacaaccccg atgatgaagg ctggaagaac ggaaccttgc aaaccaacaa cagggatgaa
    27061 accaaagaag ttcatcgctg ttacttcacc accttgagca actgcccaag cgtttggaag
    27121 tgagccagag acaagcatca taccaagaac gataccaacg gcaggatttc caccaaatac
    27181 acggaaggtt gaccacacaa ccaaacctgg caagatgatg aaggctgtat ctgtcaagat
    27241 ttgtgtgtaa gttgcaaagt cacctggaag tggcatttca agagcgttga aaagaccacg
    27301 cacacccatg aagagacctg tcgctacgat aactgggatg attggaacga aaacatcacc
    27361 gaaagtacgg atagcacgtt ggaaccagtt cccttgttta gcaacttctg ctttcatgtc
    27421 atccttagat gatgttggta agccaagtac aacaacttca tcgtacattt tgttaactgt
    27481 acctgtacca aagataattt ggtattgccc tgagttaaag aaagcacctt gaactttttc
    27541 caagttctca atcacttctt tattgatttt ctcttcatct ttgaccatga cacgtagacg
    27601 agtcgcacag tgggcaacac tattgacatt ttcacgtccg cccaaggcat cgatgacttt
    27661 ttttgcaatt tcctgattgt tcatttgcaa aaatctcctt atataacatt ttgttcttgt
    27721 ttgaaagcga ttttattcgc ccttacgact attattttat catgttttaa aaatatgtca
    27781 agcgttttgc agaaaaaata ttctatccac ttagtgggca agttttagat tgattgtttt
    27841 tgactgtttc atcaggaatt ccttgaaaaa taagtttgaa accttggtta aaaagtcttt
    27901 tatttcatta tctttcacat tttcgtaaaa atttgattga tttcctgtat ttattttatg
    27961 ataatcgttt gacagttttt cctctttttt aacataaaag gcttgcattt tttatcgaaa
    28021 acagttacta ttaaaagtga taagattttt ggaggaatga atggaatgga caactgagcg
    28081 tcgttacaga ctttatcaag attggacgca agaagaaatt caacatataa aggaaaatat
    28141 ggcacaatct ccatggcata ctcattacca tgttgagcca aaaacaggac ttctcaacga
    28201 cccaaatggc ttttcttact ttgatggcaa gtggatcctc ttttaccaga attttccttt
    28261 tggtgcagcc cacggtttga aatcttgggc acagctagaa agtgatgatt tggttcactt
    28321 taaagaaact ggaatcaaag ttttaccaga tactccatta gatagccacg gtgcctactc
    28381 tggttctgcc atgcaatttg gcgataactt attcctattt tatacaggaa atgttcgcga
    28441 tgaaaactgg atccgtcacc cataccagat cggtgctttg atggacaagg agggtaagat
    28501 tacaaagatt gacaagatct tgattgacca gccagcagac tctactgacc acttccgcga
    28561 tccacaaatt tttaacttta aaggtcaata ctatgctgtc gtcggtggac aggacttgga
    28621 gaaaaaaggc ttcgtccgtc tctacaaggc tgtcaataac gactacacaa actggcaagc
    28681 agttggcgac cttgactttg ctaacgaccg tactgcctac atgatggaat gtcctaatct
    28741 ggtctttgta gaggaacatc ctgtccttct ctactgtcca caaggattgg ataagaaagt
    28801 tctagactac gataatatct ttccaaatat gtataagatt ggggcttcct ttgaccctaa
    28861 aaatgccaaa atggtagatg tgtctcaact tcaaaacatg gattacggtt tcgaagccta
    28921 tgcaactcaa gccttcaacg ctcctgatgg gcgtgctcta gcagttagct ggcttggttt
    28981 gccagatgtt tcttacccat ctgaccgttt tgaccaccaa ggaaccttct ctttggtcaa
    29041 ggaactcact atcaaagacg acaagctcta ccagtatcca gtcgctgcta ttaaggacct
    29101 tcgtgcttct gaagaagcct tctcaaaccg ttcccaaacc aagaacactt acgaacttga
    29161 actcaacttg gaagctaata gccagagcga gattgtctta cttgctgata aagaaggtaa
    29221 gggactttca atcaactttg accttgtaaa cggtcaagtg acagtggatc gtagccaggc
    29281 tggagaacag tatgcccaag aatttgggac aactcgttct tgccctatcg agaatcaggc
    29341 tactactgct acaatcttca tcgataactc tgtctttgaa attttcatca ataaaggaga
    29401 aaaagtattt tctggtcgtg tcttcccaca tgcggaccaa aatggtatcc tgatcaaatc
    29461 tggaaaccca actggaactt actatgaatt agattatggt cgcaaaacta actgatgtcg
    29521 ccaaacttgc aggcgtcagt cctactaccg tttctcgggt tatcaataaa aaaggatatc
    29581 tatctgagaa aaccatccaa aaagtcaatg aagccatgag agaattaggc tataaaccca
    29641 acaacctggc tcgtagtctg caaggaaaat cagctaagtt aatcggcttg attttcccca
    29701 atatttccaa tgttttctat gcagaattga ttgataaatt ggaacaccaa ctcttcaaaa
    29761 atggttacaa gaccatcatc tgcaacagtg aacatgattc tgagaaggaa cgcgaataca
    29821 tcgaaatgtt ggaagccaat caggtagacg gcatcatttc tggtagtcac aacctaggaa
    29881 tcgaagacta caatcgtgtg acagcgccga ttatttcctt tgaccgaaac ctatcgccag
    29941 acatccctgt tgtctcctct gacaactatg ctggtggggt tcttgctgcc caaaccttgg
    30001 tcaagacagg tgcccagtct atcatcatga ttacagggaa tgacaattcc aattcgccaa
    30061 ccggactgcg ccacgctggt tttgcatccg tactcccaaa agctcctatt atcaatgttt
    30121 ccagtgactt ttctcccgtc agaaaagaaa tggaaatcaa gaatatcttg acccgggaaa
    30181 aaccagatgc catttttgct tcggatgatt tgacagctat tctggtcatt aaaatcgctc
    30241 aagaattggg catttctgtc ccaaaagagc tcaaggtcat cggctatgat gggacctact
    30301 ttatcgaaaa ttactaccct caattggcta ctatcaagca acctttggaa gagattgctt
    30361 gtctcactat tgatcttctc ttgcaaaaga ttgaaggcaa ggaagtcgcc acaactggtt
    30421 acttcttacc agttacgcta ttaccaggaa aaagtattta aacacaagaa aactcagacc
    30481 gattcgtctg agtttttatg atcttaaatt ttcgagatag cgctgggctg tctctaggtt
    30541 aaaggtttta tctgagatga ggcgctctac taggggagca acttcagatt cactagcccc
    30601 agctaggaga gctagggatt tggcctgtag tttcatgtgg ccttgctgga tgcccgtact
    30661 taccaaggct ttgagggctg caaaattttg agcaagaccg atggacacga taatctgggc
    30721 taattctctg gcagaaggat ttcctagtag atcatgactg agagctacac gtgggttgag
    30781 gccgatagag ccacccttag tcgctacagg catgggcagg gtcatctcac cgaccaattc
    30841 ttctctttca aggtccagcg tccagcagct aagaccttga tagcgtccat ctcgactggc
    30901 aaaggcatgg gccccagctt cgatggcacg ccagtcatta ccagtggcaa tcaaaatcgc
    30961 atcaatacca ttaaaaattc ctttattatg agtagcagct cggtaaggat cagcctgcgc
    31021 aaactgacta gccaacgcaa ttttctccgc aatctctcgt ccttgatcct tttggcggct
    31081 caagtagcga aaggcgatgc gacagcttgc agtcaccaga gaatcagtcg cgtagttgga
    31141 caggattccc atgagactct gtccctgact gagttcttct aagactggtt tcaaggcttc
    31201 cagcatggtg ttgagcatat tggcacccat ggcttcctgg gtatcgacat gaatataaac
    31261 aacgagaaag tctggttcgc cttttatctg ctcgacatgc agatcacgcg ccccaccccc
    31321 acgtttaacg atagaaggat aggcttgatt ggcaagctcc aagagctccg ctttcttgct
    31381 ggcaatcttc tcttgcgcta gtttaggatt agcaacttga taaagggcta cctgcccaat
    31441 catctggcgc tgatggactt gtgcagtaaa accacctgca cgcttgatga ttttgctggc
    31501 atagctggcc gccgcaacca cagagggttc ttctgtcaca tagggaacgg tgtattcctg
    31561 accgttgaca agtacctccg gaaccagtga ataaggcaga gaaaaagttc ccactacatt
    31621 ctcactcagc tggtctgcca cagtcacgct catctgttca tccttctcca gactagcttg
    31681 tctctcagga ctaaggagcg cctgagcttt taacagctcg aggcgctctt ggtatgattt
    31741 tttagaaaat ccattccaac ttatcttcat tatttttcaa ccttgctata acggcgttgg
    31801 tggtcgagaa tttcaaccaa ggcaaaatct tgattttcat agccagcaaa ctgggcagag
    31861 tttgtttcat ccaagtttac ttcctcaaaa aagacctttt catagtctgc aacggatagg
    31921 gcagttcgtt ggttgagctt gttcaaacgg tctttatcca aataagcttc atatccttca
    31981 accaattcac cactgaagaa ctcagccaca gctccacttc cgtaactata aagggcgatt
    32041 ttatccccag ctttcaagct atctgtattt tccaagagag acaaaagtcc aaggaaaagt
    32101 gaacctgtgt agatattccc caccttttga ctgtagagaa tagactggtc aaaatgcttt
    32161 tgtaagaggt cttttttctc ttgaggcagg ctcttatcca tgattttttt caagcctttt
    32221 agcgctaatt taggataagg caagtggaaa caaacagccg caaaatcatc caaagtaagc
    32281 tggtagcgtt tttgatattc aagccaagtc gttttcaaac tatccaagta ttgttgggta
    32341 gaatagacac catttacata aggagttgtc gagtaatttg gtcgccagaa atccatgatg
    32401 tcacgggtct gagctacatt gtcattatta aaggccatca tgcgtggatt ttgtgtaatc
    32461 aacatagcca cacttccagc accttgagtt ggttctcccg gagtttcaat accatatttg
    32521 gcaatatcac tggcaatgac caagaccttg gactccggag aattttccac atgcaatttg
    32581 gcataatgga gggcagctgt cgccccatag caggcttctt taatctcgaa actacgagca
    32641 aagggctgga tgcccagcaa gccatgcaca aagacggccg cagccttact ctggtcaatt
    32701 cctgactcgg tagccacaat gaccatgtca acttcttgtc tttcttgctc agttaaaata
    32761 gagtcactag cactggccgc caaggtcacg atgtcctcag ttaggggcgc aatactcaat
    32821 tccttgagta agagtccttt acttaatttt tcagggtcaa ttcccctcgc ttctgctaag
    32881 tcttgtaatt tcaagacata ttgactggtc gcaaaaccaa tcttatcaat accgattgtc
    32941 atatttacct ctgttttatc attcatgtaa aaaatcgttc tatactattt tatcacaaat
    33001 ggcagtaaaa gagagaaaaa agacttgatt caccaaatca agcctcttat tggtcatcat
    33061 tttaaagaat gattagttgc tagagagttc accgatataa gtagctttat aagctccatt
    33121 cacagttatc agctcctgga ggatcaaatt tcctgagtaa gtccttccca tctcatctac
    33181 aaatttttga taaaactgac tggtcggaat ttctctgaca tccttatcaa atgtcttgtc
    33241 aagtgtttta ctaaccttct cagcaatcaa ttgatgctct tgccatccac tttgaaactc
    33301 tgagccccaa ctagaaacca tgactgggat aaacaacaag gtcagtagac ttacagacaa
    33361 taaggaaaat agtagacttc ctgcaaaact agaatcctag ttcatgattg ataatgccag
    33421 caatcaaatt cattcgtaat ccgaagcgtt tacgatgatt tcgatagatt gttgaaaaca
    33481 ttttaaacgt ttttactttg gcaaagatgt tctcaacctt gcttctctcc ttggatagcg
    33541 catggttaca agctttatct tcagctgtta gcggcttgag tttgctggat ttacgtggag
    33601 tttgtacttg aggatatatc ttcatgagcc cttgataacc actgtcagac aagattttac
    33661 cagcttgtcc gatatttctg c
//
LOCUS       DBERAE010000020        33330 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.20, whole genome shotgun sequence.
ACCESSION   DBERAE010000020 DBERAE010000000
VERSION     DBERAE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.20"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(40..924)
                     /locus_tag="ACL70N_001129"
     CDS             complement(40..924)
                     /locus_tag="ACL70N_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS0589937.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(1069..2220)
                     /locus_tag="ACL70N_001130"
     CDS             complement(1069..2220)
                     /locus_tag="ACL70N_001130"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGS0589938.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(2366..4132)
                     /locus_tag="ACL70N_001131"
     CDS             complement(2366..4132)
                     /locus_tag="ACL70N_001131"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGS0589939.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTEHPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            complement(4215..7331)
                     /locus_tag="ACL70N_001132"
     CDS             complement(4215..7331)
                     /locus_tag="ACL70N_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGS0589940.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(7341..9635)
                     /locus_tag="ACL70N_001133"
     CDS             complement(7341..9635)
                     /locus_tag="ACL70N_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS0589941.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(9694..10494)
                     /locus_tag="ACL70N_001134"
     CDS             complement(9694..10494)
                     /locus_tag="ACL70N_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0589942.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(10491..11264)
                     /locus_tag="ACL70N_001135"
     CDS             complement(10491..11264)
                     /locus_tag="ACL70N_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0589943.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(11289..11759)
                     /locus_tag="ACL70N_001136"
     CDS             complement(11289..11759)
                     /locus_tag="ACL70N_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0589944.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(11750..12181)
                     /locus_tag="ACL70N_001137"
     CDS             complement(11750..12181)
                     /locus_tag="ACL70N_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0589945.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(12174..12614)
                     /locus_tag="ACL70N_001138"
     CDS             complement(12174..12614)
                     /locus_tag="ACL70N_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGS0589946.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(12626..13264)
                     /locus_tag="ACL70N_001139"
     CDS             complement(12626..13264)
                     /locus_tag="ACL70N_001139"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGS0589947.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(13379..14782)
                     /locus_tag="ACL70N_001140"
     CDS             complement(13379..14782)
                     /locus_tag="ACL70N_001140"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGS0589948.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            14958..15731
                     /locus_tag="ACL70N_001141"
     CDS             14958..15731
                     /locus_tag="ACL70N_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0589949.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(16859..18364)
                     /gene="adcA"
                     /locus_tag="ACL70N_001142"
     CDS             complement(16859..18364)
                     /gene="adcA"
                     /locus_tag="ACL70N_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGS0589950.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(18374..19180)
                     /locus_tag="ACL70N_001143"
     CDS             complement(18374..19180)
                     /locus_tag="ACL70N_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGS0589951.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(19173..19877)
                     /locus_tag="ACL70N_001144"
     CDS             complement(19173..19877)
                     /locus_tag="ACL70N_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0589952.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            complement(19877..20317)
                     /gene="adcR"
                     /locus_tag="ACL70N_001145"
     CDS             complement(19877..20317)
                     /gene="adcR"
                     /locus_tag="ACL70N_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGS0589953.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(20472..21740)
                     /gene="dltD"
                     /locus_tag="ACL70N_001146"
     CDS             complement(20472..21740)
                     /gene="dltD"
                     /locus_tag="ACL70N_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGS0589954.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(21733..21972)
                     /gene="dltC"
                     /locus_tag="ACL70N_001147"
     CDS             complement(21733..21972)
                     /gene="dltC"
                     /locus_tag="ACL70N_001147"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGS0589955.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(21986..23230)
                     /gene="dltB"
                     /locus_tag="ACL70N_001148"
     CDS             complement(21986..23230)
                     /gene="dltB"
                     /locus_tag="ACL70N_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGS0589956.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(23227..24777)
                     /gene="dltA"
                     /locus_tag="ACL70N_001149"
     CDS             complement(23227..24777)
                     /gene="dltA"
                     /locus_tag="ACL70N_001149"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGS0589957.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     ITDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(24798..24929)
                     /locus_tag="ACL70N_001150"
     CDS             complement(24798..24929)
                     /locus_tag="ACL70N_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGS0589958.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(25160..25864)
                     /locus_tag="ACL70N_001151"
     CDS             complement(25160..25864)
                     /locus_tag="ACL70N_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS0589959.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPISNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(25934..27760)
                     /gene="glpO"
                     /locus_tag="ACL70N_001152"
     CDS             complement(25934..27760)
                     /gene="glpO"
                     /locus_tag="ACL70N_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGS0589960.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(27802..29310)
                     /gene="glpK"
                     /locus_tag="ACL70N_001153"
     CDS             complement(27802..29310)
                     /gene="glpK"
                     /locus_tag="ACL70N_001153"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGS0589961.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(29469..30896)
                     /locus_tag="ACL70N_001154"
     CDS             complement(29469..30896)
                     /locus_tag="ACL70N_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0589962.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            31061..31933
                     /gene="hslO"
                     /locus_tag="ACL70N_001155"
     CDS             31061..31933
                     /gene="hslO"
                     /locus_tag="ACL70N_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGS0589963.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            31920..32900
                     /gene="dusB"
                     /locus_tag="ACL70N_001156"
     CDS             31920..32900
                     /gene="dusB"
                     /locus_tag="ACL70N_001156"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGS0589964.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(33130..>33330)
                     /locus_tag="ACL70N_001157"
     CDS             complement(33130..>33330)
                     /locus_tag="ACL70N_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HGS0589965.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
BASE COUNT         9996 a         7364 c         5782 g        10188 t
ORIGIN      
        1 tgacgtggtt tgaagagatt ttcgaagagt attagtctat tatttcttct cagcgcgaag
       61 ggctgacaag atttgtgttc ggatatcatc cacaccattt ggagtatttg gtaaaaagat
      121 ggtttgattt cctttagagg caaaggtatt caaggtatcc aaatactggt tggtcaagag
      181 gatagacatg atttgttctt ctgtcatgcc aacattggct tccttgagtt cggtgataga
      241 ctctgccaat ccatccacaa tcgccttacg ttgttgggca atccccacac catgaaggcg
      301 gtctttttct gcttctgctt cagctgcagt gacaatttta atcttgtcag cttccgccaa
      361 ttcttgtgct gcgacccgct tacgttgcgc cgcattgatt tcattcatgg attgcttaac
      421 ttctgcatct ggttcgacct tggtaatcaa ggttttcacg ataatgtagc cgtaagtggt
      481 catttcttct gctacttggt gttgaacctc aagggcaatc tcatcttttt tctcaaacaa
      541 ttcatccaag gttaattttg gaacagaaga gcgaagagca tcttcgatat aagatttaat
      601 ctgagattct ggacgtatga gtttatagta agcatctgtc acgctctgct cgttgacacg
      661 gtactgagtc gctacattca tcataacgaa cacattgtcc ttggtcttag tctcaaccac
      721 aatatcactt tgcaacaagc gcaactgaat ccgtgctgca atcgagtcaa tcccaaaagg
      781 caagcgaata tgaataccgc tattagcaac cttttggtat ttcccaaagc gttcaataat
      841 cgccaccgac tgctgacgaa ccacataaac tgtactcagt gtgactatca ccaataggag
      901 cacacaaaca atcagaaaaa tcatgaaaaa tattgccata atggaacctc cacaagtatt
      961 tttctagtat tatagcacat ttaaagaagg ctgtgccgtt tttactgcga tttttcctga
     1021 aatgtcaata attagaggtg aattgtccta ttgtcgtcca atctcttgct aaaataactc
     1081 tttataaaag gcaatcgttt cttctaaggt tggcataaat ggatttcctg gtgcgcaggc
     1141 atcaatcaag gcattcttag aaaggtattc aaagtcgaaa tctttttctt caataccaag
     1201 ttcagtcagt ttcttaggaa tacctactgt ctcagaaagc ttctcaatct cagcaatcgc
     1261 ataatcggca cattcttgat ctgatttacc ttctacatga agtcccaagg ctttggcaac
     1321 attgcggaaa gcttctggta cacgtttagc attttcacgt tctataactg gtagcaacat
     1381 ggcacagcac acgccatgtg gcaaattata tactgcaccg agttggtgag ccattgagtg
     1441 aacataacca agaccagcat tattaaagct cataccacca aggaagatgg cattgaccat
     1501 accttcacgc gcttcaatat catgtccatt ttctacagca cgaggaagat attccttgat
     1561 aagctcaata gcaccaatag acagtttctt ggttacatca taagcaccag gtgttaccaa
     1621 agcttcaaca gcgtgagtca gagcatccat accagtagca gcagtcaggc ctttaggttt
     1681 ggaaagcatg agttccgggt cattaacaga gataagagca aggctattct tgtcaaccat
     1741 taccatctta accttgcgtt cttcatcagt aatcacatag ttaatagtga tttctgcaga
     1801 agttcctgcc gttgtattga tagccacaac tggcaagcct tttttagcag acttatgaag
     1861 cccttcataa tcctgtggtt ttccaccatt tgtagccatg atagaaatac aactagctgc
     1921 atcctgtgga gaacccccgc caagactgat gataaagtca cagccatgtt cttgcaaagc
     1981 agctacccca tctgtgacat ttttacaagt agggtttggc tctacatcgc taaagatgac
     2041 atattcgatt ccttctgtat ccagtggttt taaagtctta ggtaaaatat cactgccttc
     2101 gatgtactta tctgtaacca aaagtgcctt tttatagcca agttccttga tataaggacc
     2161 cacttcattt acaacacctt ttccaataag gttgactgcc ggaacataaa atgtagccat
     2221 ataattttcc tcctgcgcct ccgcgctatc tatttaacat cattatatta ctttttgtat
     2281 tcgtttttaa ttatttgtga attgtttaac aaatcttttt aaaaggatag gagggacgta
     2341 agttcacctc ctatataaac aagttttatt tatgtagtgg tcccaacaac tgacatgcac
     2401 aatagtctgc tgattctaga tcttctgttc caaataagga ccaattttta ggtctaaaga
     2461 tatcttcctc aggtacatta tgcatattga caggaattct caacatagaa gccaaggtaa
     2521 tcaagtctgc tccaatgtgt ccatatgtta tggctccgtg attagctccc caattattca
     2581 tgacgtcata gacagacttg aaagcacctt ttcctgtcaa acgtggagca aaccaagtag
     2641 ttggccatcc tggatctgta cgattatcta aagtatggtg aacatcttca ggaagttcaa
     2701 gtgtataacc ttctgcaatt tgtagcactg gaccaacccc ttttagaaga ttgagacgta
     2761 ccattgttac tggcatatcc cccttcgtca agaaacgagt tgagaatcct cctccacgga
     2821 agtattcgcg gtttgctggt gggaagtctg tattttcaag catagcctgc acttcacttt
     2881 cttccaactc ccagaatggt ttcataacag gtttgccatc tcgagtagct tgacctgtac
     2941 catccaatgt acaagaacca gagttgatta gatgtaagaa gccagctgca gcacgaccct
     3001 ctaaagtatg tcccgttaca cgtttaacag cctctgggct ccaataagta cgcacatcag
     3061 caaagatttg tggagtattt gttaatagat aattaaagag catagacaca ccatttagtg
     3121 aatcattctc tgtcgcaaat acaaatggtt ttcgaatacc attccagtca aactgagtat
     3181 tgaggaaagt ttccataaaa tctccatttg gaaaatggtc tgtccactga cgttgacctt
     3241 ggaaaccagc tactaaagca tggtgaccaa ctgcttcttc ctcaaaacca agttcagcaa
     3301 gtcttgggtt accaaccatt aagtcacgtc caatcatgaa catcttaata acaaattccc
     3361 attgtctatc tttttcttca cggcttaaaa caaggtcttc acggttatgg tcgaatcctt
     3421 cttttacgtt ttctttcacc catttgagcg cacgttcgaa ctcttcaggg tcgtaaatac
     3481 tacggtccat acggcgcgtg aactccgtca tatctaccga ttcatttcgc attcctaggt
     3541 attcttggaa gaaatccgga tttacaatag aaccaccaat ccccatcgaa acactaccca
     3601 ttgataggta agcagtgtct ctcatcaagc cagttgcaag agctgcacgc gcatagcgta
     3661 aaagtttttc tttgacatct tctggaatat ctgtgtcact agcttcctga acatctcttc
     3721 cataaatccc aaaggctgga atcccttttt gagcatgtga agctagtaca gctgcaagat
     3781 agacagctcc tgggtgttct gtcccattaa atccccaaat agcatgagga atatctggag
     3841 acatatccat agtttcacta ccataacacc agcatggtgt aactgtaatt gttgcgcaaa
     3901 catttgattt tttaaacaac tcatgggaag ctgcagcctc tggtacacgg ccaatagtag
     3961 atggagaaat cacgcattcc acaggttccc catctggata tttcaatgtg cttgaaatca
     4021 aatctgccac acttttagcc atgttcattg tttgcacttc aagtgattcg cgtacacctt
     4081 gacgacgacc atcaatagtc ggacgaatcc caatacgtgg atgttgaatc atactatttt
     4141 cctcttattt ttctgtttct ttcatactac catctccatt atatttacgg tagcctgggt
     4201 gataattttt aaaattactt ataagtataa acctctacct ctgctaaact taaaggaatt
     4261 cctgcgcttc tcaaagaaat tctaaccttt tttcccttca gtccttttaa gtctatggat
     4321 agattattgc tttctaaact gtcaatatgt tgtgtaaaaa cttcataatc atttgaatca
     4381 tatataataa tatcaaaatt tgataatctc tgaatttcag catctgttct attataaata
     4441 attaactttt ctaattcttc ggtttgtgct aaatctatct cccaccatga aggagaatct
     4501 tctttggtat gagtcactga atgatgacca taatctccgt ttttatttcc atcaactgct
     4561 agacgagaaa aaccattgta atccgttgaa ctctgtcgag tttcttttgt taatgcaata
     4621 ttagaaagtt tcttcggagt tctctttgaa ccatagactt caacttccgc taaacttaac
     4681 ggaatagctg ctgattttaa ttctattttg actagcttag cccctacaga aggtactttt
     4741 aaagataaca aaccatcaac tactttatca aaatgtcttc taaaaacttc ttctcctgat
     4801 gaagatagaa aaataacatc aaaattagat aaacgctgag gttcggcatc tgttctatta
     4861 taaatatcaa ctttagaaac cgtaaactct tctcccagat cgacctgcca ccaagcgtta
     4921 gaatctgcct tagtatgagt caccgaatga tgtccgtaat ctccatcttt attaccatca
     4981 actgctaaag cagctacacc ctcataattg gttgaacttt gagtagctac cttatttgta
     5041 gagactactt tatcttctgt tattttatct atatcctctt cagattgctt accatctgat
     5101 tctctaaaaa cctctacttc tgctaaactc aaaggcactc cactcgttag taatttaact
     5161 ttaatatacc ttgctccttt ttctttgaaa tctagactaa cagattcacc cgacaaatta
     5221 ttaacatgtt tcttagcaac ttcgtttcta ttattgtcat atagaatcac atcaaaatta
     5281 gatagacgtt gagtctcagc atctgtgcga ttataaattt taacaagccc aactttatcc
     5341 atttttttca aatcgacttc ccaccaagag ggattatctg ccctagtgtg tgttaccgaa
     5401 ccagagttaa aattaccatt tctgttacca tccacagctc tattagggtc tccattgtaa
     5461 tctacagaac tttgtgttgt tggttttgca tatgctatat tcaaattacc atcattaaat
     5521 ttatctggtg ttgggaaaga gactggacct gtcccctcag tatttataga catctctacc
     5581 attccattat gattaaccgt aatggtataa acatgggtat tctcatccca attttctgta
     5641 taagtataat gatttttatc gccacttata tttatctgag gtttatgacc agtatgccct
     5701 tttaatgtaa gtgttgttgt cctaaagtca ttatctacag gattgatgga ataatttttg
     5761 cttatccagt tcgctaactc taattcttct ttcttccaac tttttgatgc atcaaaattt
     5821 cctgataatg cccacatagc tgtcttatct gtcctgtaat tattcaataa aatatgtaaa
     5881 ttatttggat tttctttaac aacagcgtaa gtatgtggcg tcaaatctaa cgataacgac
     5941 tttgtattat tagtatacat aggcaacatt acttgctgat ttttattgat attagcatta
     6001 ctattataaa tataccagga attacctaca cgctgagcat acccatctcc ttcataaagt
     6061 tttggataaa gcgagtttaa atagttgact ttactagaca attcctcact atttttagtc
     6121 aaaatttttg cattagggaa tatagatgaa atcttttcct tatcaatttt ctcatgtatt
     6181 acaggaagaa tatgatatct cccattatta tataaaggca ttgtttcatc attcgaataa
     6241 agtccttgat aaaatccgtt taatgaacta atcctacctt ctccattcca aaatacagct
     6301 tttgttctat ttacaacttc ttccttactt ggagctggat tttgtatagc atgtctaaag
     6361 aaaggaataa tacctttagt aaatgctgga gttggtacat catttgtcat aaatgtatac
     6421 gcggcacatt cgaaattata aactgtgcct cccccagtat atacattcat catttccata
     6481 gcaatcattg attctggttc cgatgcatag gatctcatat ccctagctct tccagtttca
     6541 aatgtgtttg tataatgttt ttcccaccat ttccatgtat ctgttgatga gccccagtta
     6601 tcacataagc cactcaacca aaatccacta acgatagaat ctgtacccgc atcatctctt
     6661 attggcgtat ttttagttgc caacaccaaa tttttatgat atttttgact cgcttcaaag
     6721 aatgtcggat cattcataat agtttcccag aaccattttt catgatcatg ccagataaaa
     6781 tgcgctccat atttggcaca aacttccaaa tatttagcac tatgcggagc taactggtta
     6841 ttgtaaatcc aataattctc aatatttaaa acacctttta acacactata cttttggaat
     6901 tgttcatcta accactctgg aggaactgta ttacgctctc cagccgacat aataaccaag
     6961 aaaactggaa tgtttagact ttgagcttcc tccaacatct tgacatacca ttctctcaat
     7021 tctttcgtat ctcgtggaat acaacttgtt ggtttacaga cttttgcagg atgaagttca
     7081 atcgctgcat atggctttac atcttcagga atagcttccc atgctccctt caatgtgttc
     7141 ccccaccata atccgttacc attatcattg ccatacaacg gagaaagcaa caatggcgat
     7201 tcattattaa tcgtcgttct catttgaaca cgattatcag ccttaactcc tgctaacaat
     7261 ccaaaacata acatcccaat acatacaaac aatattgtga ttaattttct ttttattttt
     7321 tctttattca tgacttatac ctaaaaattt aactcaataa ttttttctga attaaatacc
     7381 aattcaatat tttgtacatc agtatttttg ccatatattc ttactcttac tttttgatct
     7441 ttgtttcctc cttccaattt taggaatgtt atatccccat ttttccaagc aaacgatacc
     7501 ttatatcctc ctcttactct gaaacctttc acttctcctt ctgaccaagc agaaggtaaa
     7561 gctggaatta gtgataacca attatgatgg ctctgtacta ataattcaca aattccactc
     7621 accaaaccta aattaccatc aatttgaaat ggtggatggt caagaaataa attgccaaga
     7681 gtcgcattat ttaacaaacc attaatctgg ttataagcag gttcaccttg atatagtctc
     7741 gcaaaaaaat gaatcagcca tgcagcactc caacctgttt gtgtactagc atgcaaacca
     7801 cttactaacc aattattaat cgcttgctcc ctctcctgtg aagataaaaa attagcgttt
     7861 gataatctcc tattgatagt gattttagct gcttctgcta attccggagt tttatgaata
     7921 tcaatctcat tataaggata aagcccaaat agaggtgaaa tgtgtctatg cccaggctct
     7981 acttcttcat aatcttctaa ccattcttgg atttgcccat tactacctat ttttgtttta
     8041 ggtagtttct tttttaactc cttcacacga ctaataaaat ccgaattgtc tcctaattgt
     8101 tttgcaatgc caatgcatga atcacaaaaa tatcttagaa tttgattatc aattgtagat
     8161 gatagacaag catttccttc aataccattt tttaagcgat atttattttc cggtgagaca
     8221 cttggacctg tcatcaagta gccatccacc tcaaataaat aatcttcaaa gaaaagaaat
     8281 gcttctttta tcatttcaaa atgttccgta agaatacgct catcttggaa atataaatag
     8341 tgttcccaaa tatgagtaca taaccatgga atagttaata cccaaattgc agcccccatg
     8401 gcatgagatt ggggagccgt atcgccaaaa ccatccgtat tatgatgtgc tgtaaaacct
     8461 ctagctccat acattttctt agcggttagt cttcccggtt ctctcattct ttcgagcata
     8521 tcaaataatg gatattctac ttctggtaaa tcacatggac ctaccatcca ataattcatt
     8581 tgagtattaa tattaatcgt atatttagaa ccccaaattg gatttaattc atcacaccat
     8641 attccttgaa gattggcagg taaaccattc ggttgactag acgatattaa cagatatctt
     8701 ccataatgaa ataacaagtt agtcaagtag ttactatact ttttagtgtt ttcaagaagt
     8761 agattcgttg gaatgctaag acaatcttta ctatagtcta gtttaaaatc aactctatta
     8821 aattgctcct gatatttttt tacatgttca tctttttctg taaagtaatc aatactacta
     8881 aattctccct gaagagaaga aatatctata tttccccaat aatccgtcat tgatttgaga
     8941 taaagaaata cctctgtagc attccgaata actattgtct ctcccaatac acttacttca
     9001 ccatccgtaa ccttagaatg acatactact ttaaactgaa caccttttct acctccagca
     9061 gaggccgaca ttaaaattgt acttgaatcc agtttagata cttcgtcatt aaaccgttta
     9121 tttctaccca aattaatgtt taaatttaat gtgttttgaa ctgatgacac tatacggcaa
     9181 cataaaatat tcttattaaa actcgtaaaa tattctcttt ttatttgtaa attacaacta
     9241 ttaggctcaa acacaacatt agaaatagct gtatctaaat ctagctctct ttcatacaat
     9301 gaaagagcac aagactgaat atctatatgc tcaatgtaaa gttccccaag taattcatag
     9361 tggctttgat ctcttggggt agcaaacatt gttaacttta tcaattcttc ggctttctga
     9421 atttctccat ctaaaagata ttcccgaatt tttttaagat gcaatagtga gtctggatta
     9481 tttctatctg actttcctct ataccaaata gtctcatcgt ttagttgaat acattctttt
     9541 gtagctgaac cataaatcat accacctaaa tgaccgttcc caatcggcaa ggcttcattc
     9601 caatttgagg cagctttctt ataccataat ttcactcttt acctctcttc caaaatggag
     9661 gtgatatccc aaataccacc tccacacttt ctactacttc aaaattccta aaacaactag
     9721 gataactcca atagccataa cactaaagat tagtacaacc ggattctttc cttttctaat
     9781 taatttacac attaataaag tcaaagccat agggataaat cctggaatta attttgtaat
     9841 catttcttga acagaaataa caagttcccc ctgcttaaat tctaatccaa aattaatacc
     9901 aaccattgat ggaatcaaac cacccactag tactagccct aatgctgtcg ccatactcgt
     9961 aacgcgattc aatgttcctt ttgtattatt ttcttggata agactagaac ccttagtata
    10021 cccatatttc aaaccgaaat atttaacagg aatattaata atattaaaca atattaaggc
    10081 gataaagata cctaaagcac cgccgtcttt agaataagac gcaccaatac taaaacagat
    10141 aggaactagt gtcagccaga acaaactatc tcctagacca gccagtggcc ccatcaagcc
    10201 aactttaata ccagtaattg aagctgcacc ttcatttcct tcttgttctt ccatagcgga
    10261 agtaactcca agaataaatg gtgccgctgt ttgatgagta ttgaaaaact caaggtgacg
    10321 tttcattgca ggagaagctg aatctttgtc tgggtatagt tttttcaata ctggaagaat
    10381 tgtatataga aaacctaggt tctgcattct ctcatagttc catgaagaac catacataaa
    10441 acttcgtttg aaaacttttt taagttcaac tttagttact ttattattca tcatagatca
    10501 agatcctcct caacatcact acttgaagtt gtttcttgtg gtttacttcc aatcatatcg
    10561 tagaagtatg ctaccgcaat accaactagt gagatcccaa tggttgacat tcctccatac
    10621 acagaacaaa tgaatccaat caacaagaat acccacatat ttttcttgag catcatattt
    10681 aaaagcatac caaaaccaat tgaaggtagt aaagcacctg cagagttaag tccctgcata
    10741 acgattggtg gaaccttagc aaacaagtct gccacatatt cccctccaag cataatagct
    10801 aggaaaattg gtacaatttt aaataacgtg attaaaacca aacttgaata atgataaaaa
    10861 ccgatctttg aataatctcc gtttttagca tcattatcag cttttttcac aaaataaaca
    10921 tctaaagttt ttgcaagaac atccaactgt tgggtagcaa ctgcaattgg aactgctata
    10981 gcgataccag cagtttctcc ttgaccagat aaaataccaa atgcagtacc aataatcgca
    11041 cctgaaatag tatctggtgg agtgtaacct ccaatacctg ttacaccgag ccaagttaat
    11101 tcaagagctg aaccaataag aacaccttgg gtgaaatctc ctaagactaa gccaaccatt
    11161 gcacttgtaa ctaacggacg gtgaatcata aataacggtc cattatagtc aatagtggca
    11221 ataatcccaa ctaatgtcac cagtaatgct tgtgtgaata gcatatactg tacctcctta
    11281 aattattttt ataaaaattt ttccaacatt gtaactttat cattaggaac catttgaatt
    11341 tcaactctcg ttcccttatc aactattttc ttaaaataat atttgtcttc ttcacctaga
    11401 gctacacctc ccgttacctt ttcattttcc tccgttttac tcatctgtcc tacattgagg
    11461 tactccaatt ttaaatttcc ttcaatagaa tcatacacat cttttggatt tgtatatatc
    11521 agcattgttc tcttttttat tggcacagag tttaaaactt ccacaaaccg ttttacacta
    11581 aagaaaacaa tttttaaacc taccggtgca gaaatcttta aaatagattg tcgtgtttta
    11641 tcttctgaga tgcgatcatt aacaatgata acttgctcaa tatcatactt ttttagccac
    11701 gtagtgacaa cttgaccatg taccagacgg tcatcaatac gaacaaactc tatagacata
    11761 aatcctcttc ctcctctacg ttaagttgtt gtttaacatt aaacaaacta ttttgagcat
    11821 tttgaacaat ttcttctaaa ttgatttttg aatcataact tgatattaat tccactagga
    11881 gagggatatt aaaccctgtt acaatatcaa ctgaatccaa atttaaaaac cgtgacaaag
    11941 ccacattatt aggacttcct ccaatcaagt cagtcaaaac gataacctct tgatttgagt
    12001 ctaacagttc atccacttga tttttaaaat aatgttcaaa ctctacaata ttctctccag
    12061 gcatcaaacc taatgtccta actctatcat ttgttgtctc accaacaaac atttctgcgg
    12121 tcatgagagc tccgctagca aaattaccat gactggcaac taaaattcct ctattaaaca
    12181 ttttctcttt caacaactac tcctttctta aggataatat tagcataaag tgaagtttct
    12241 cctgtagcaa caatagcata agctttctta ctacgttcat aaaagtcttc tcttctaaga
    12301 taagtaatcg ttttaagatc tgtaccatga ccttcaatca tctgtctata ggtaccccat
    12361 atcttaggaa tatcatcacc cgaaacaacg ttcataaact gaattgaact atcgacgtaa
    12421 ctatctaatg gcattaaata cagaatggaa tctaataatt ctggaatatt tacgccatca
    12481 caacgaatta gcttatttgc acatgaggca gaaggataat tcgcgtcagc taatactatt
    12541 tcatctccat gtcccatttc cattaaagtc ttcaataaat ctggagaaat atttttcggt
    12601 atatgtttta acattaatat cctccctatt ttctctgacc gtatgtttta aatttttctg
    12661 ccattaaatc catctcctca tcaggaagaa ctactggctc tccaaaattc ttagctaaac
    12721 aataaatttt tgcacaatat tcaacttctt caacaatatt aaatgcattc aataaatttt
    12781 gtgcacctgc taaaattcca tgattcgcta gtaaaactgc tctacgacct tccattgctt
    12841 tagctgcatt cacagccaat tctttcgtac catatgttgc atactcagct acccgaacat
    12901 ctttccctgc cactgcaatc atataatgac tagccggaag tggttctctg agacaagcta
    12961 atactgttgc ataagttgta tgagcatgga taattgcatc gatatcatca cgagtttgat
    13021 attgaatcaa atgcatatac cattcgctag atggcaagcg ttctccctct acaacatttc
    13081 cattaatatc catcactaca atatcggatt ctttgatttc aaagaaatca atacccgacg
    13141 gggtaattgc catcaattgt ttttcacgat cgaaaacact gagattccca cctgttcctt
    13201 tcgtcaaatc tgtttctact agcttcttgc catacttaat taattcttgt tttacatctg
    13261 acattcttgt cctcctcata tcaaaacact aaatattttt caattcacca attatccccc
    13321 cttcttgtac aaaacttaag aagggggagg gaggcaaatt tacaaactct caatcttttt
    13381 aattcttttg ggagtaataa ctctctaatt gtagaaactc ctcaataaca tggtgagctt
    13441 cttccatccc ttttaattgt cccatagcta tgagctgcac aacaatattc cccacagctg
    13501 taccctcagt cgaacctgta agaacctctt taccagttct atcagcaatc atttggttaa
    13561 agtaactggc tctagcacct cctccaatca catatatcct cttataaacc ttatgagtta
    13621 gttcttctag taactctatc gctttcctat acgtttcagc taggctttca taaacaatct
    13681 taaatagttg tccatctgtc cactctctag tttcatgatg ataagctaga tattctgtca
    13741 aagtcttgtg catatcagat tctgttgcaa attcagttga ttcagtatca atcagaggaa
    13801 gattttcttt ttctttctcc accattgtcc taatatcatc aaaagaatag gctttccctc
    13861 ttcgttcaaa tgaacgtctt agttcctcta tgatccacaa ccctgtacaa ttcttcagaa
    13921 atgtaatcac tccatcttta ccgacttcat ttgtaaatcc ataactgaag gattcggtag
    13981 taagaatcgg tgaagtaagt tccactccaa ccaaagacca agtacctgat gaaataaata
    14041 aactaccttc tgtcttaggt actgagacaa tcgcacttgc tgtatcatga ctacaaacat
    14101 tcacaacagg aatatcgcct aaaccatact ccttttttat ccttccaaga acatttccct
    14161 ctgaaacaat ttcaggaagt aaagatgaat ccaattcaaa tagttttaag atattctgat
    14221 tccaattttg actcctagga tcaaataatt gagttgttga agcaatgctt ttttctgtag
    14281 caaacttacc tgtcaagaga taattaaaca aatctggcat taaaagaatc ttattggtct
    14341 tatagaaaga gtcaggagat tcttgacgtg ccttaaagag ttgaaacaag gtatttatct
    14401 ccataatctg atttcctgtc tctgaataca gtttttctaa ttcagtcatt tcagatattt
    14461 cctttaacac tccctttgtt ctttcatcac gataatgaac aggttgtgat aacagcttac
    14521 cttcattatc aatcagtcca aaatcaactc cccatgtgtc aataccgata gataaaatct
    14581 tgtaactagt attagccaag cggatacttt caagaatttt agctagtaga aagtcaatat
    14641 cccaagataa atgccctttt actctaatag gtagattaga aaagcgattt atttcttcca
    14701 ttactagttt attttcagaa aggtaaccaa cgattgctct tccagaagtc gcacctaaat
    14761 ctattgctaa aaccgcttcc atttttcttc tctcttcgtc cttgattaag tttattataa
    14821 tccccacatt ttattttttc aatatgtgaa cgcttacttg gataatgttc aaatgttaac
    14881 ccaatattca taaaaataat tcaaattcct ccaatttgtg ctataatata gttgaaatga
    14941 taaattagga ggagcttatg ataaaagatg aacgtgtact tgaattgatt gaaattatta
    15001 aaaagaaaaa aagaattgcc gtaaaagagc tggcagaaat cactttctcc agcacaagta
    15061 ccttacgtcg tgatttaatt ttcttagaaa atcaaggtct tatcaaaaga aagcacggat
    15121 acgtgaccct gtcctctatg aacacaattg aactttctca tcaaatacgg gaaggagaaa
    15181 gtactaggca aaaaagacta atcgctagtc tcgctaaaga ctttattcgg tcaggtatgt
    15241 gtgtttatct ggattccagt acgactgtct acgaactttg tccctatctt tctgaacttg
    15301 ataatttgat tatttttaca aatggtttac atactgcaca aaccctatct gaaactgtta
    15361 aagatagctc caaaatcttt atcacatctg gcgaggtcaa acatcaatcc tgttccgtgg
    15421 tcaattacga taaggaaaat tctttattag atcattttaa tatcgattta gcattttgtt
    15481 cagcaagagg tattgatgac caatatgttt atgaagcttc tctcagccaa gctatttcaa
    15541 aaaagaatat tattgacaaa gcccatgaaa ccatcttact gattgatagc tctaaatttt
    15601 acaagactgg attttttaaa attaatcccc tatccaaata cacaaccttt atttctgaca
    15661 ccgtgccaga tcaaaaatta ttagacgcag tcgaattatt tgatggagaa tgggtttctg
    15721 atattcaatg aaaatcaaat aggaagctag tctcagcttg ctcaaagtac agatttgaaa
    15781 actgatgaag tcaagtcccc catggacacg gcaagacgaa gctgacatga tgtgaagaga
    15841 ttttcgaaga atactcgttc tgtctgctga ctgatttaca aatattcacc acatgacatt
    15901 attttcttag caaccctaaa aacagaggct ggacaaaaac tcaatttcaa gagaaatggg
    15961 gcaaatattc ccacaataaa acgcatagta tcaagttttt gcacacctga tattatgcgt
    16021 ttttctgatt ttaaagactt tgtcgcctag accctatatt tcaagaatta agtgaccttg
    16081 atgatctaaa tgtattgtgg tatactattt ttgtcatcgg ttaccgatta cgttcctatg
    16141 ggttcgtgag aggaggtgaa actaatgagc cttatcatag agctcgctct tactattata
    16201 gcggatgtta tagctggaat tatcttgtat ttcatctgca gatggctaga tagtaaggag
    16261 tagaccgaat gactagccta taaacacccg ttaaatctct aagatacgtc aaaaaagccc
    16321 ttaactacgg ccatagttag gggctttggt gttctaatga accttatcaa ttaactacat
    16381 tttagcatat aatctacaat agttcaagca ttaagtgagg ttgatgatct aaatttagtg
    16441 tggtatacta tttttgtcat cggttaccga ttatgttcct atgggttcgt gagaggaggt
    16501 gaaactaatg agccttatac cagagcttgc tcttactatt atagcagatg ttatagctgg
    16561 aattatcttg tatttcgtct gcaaatggct agatggtaag aagtagaccg actgactagc
    16621 ctataaacac ccgttaaatc actaagatac gtcaaaaaag cccttaacta tggcactagt
    16681 taggggcttt ggtgttctaa tgaaccttat acactaacta cattctagca tataagtcct
    16741 aatatttcaa gagttttatt tattttttca ggttccctta gttctgaaag gtctataatg
    16801 aagttagcca tctagtatca aaaaaccgac tagctcttat gaactagtcg atttctcatc
    16861 aatgcgccaa catttcttgg gcgatttctt ggccagatag gttatctggg tagtaggttg
    16921 gccagttgtc catttcttca aagagggctt cttggcttgt gcctccaaag aagatatgga
    16981 aatgttctgc cttaactggg gcgatattgt ggtcactaaa ctgaacatac ttgaattgtc
    17041 cagcgtcagc atctgtggct tcaaagagga aacgcacgcc acgattgcct ttcttgtaag
    17101 tcaaaatttt cttaccgaca tacttgtaag tgtatttctt gctttgtcca ccttgaacaa
    17161 attccatagt attatcagta atgttaatct tagtcacatc tgtctgatag ccttttgtat
    17221 agtaagcctt gtactcagcc tgggtcatct taccagtcaa cttagccttg tagtcaaaga
    17281 cttggtcaaa cgtgccgtct tcaaggaaag gataaactga ttgccagtta cctgcatagt
    17341 cactcaaggt gcggtccttg acagctgcat cctcgaagta accattttgg actgtcttgg
    17401 tatcctctgc cttttcaggc tcgattgctg ggccttcttg gtctgttgtt tgtttcaaag
    17461 ccttgaggtt tttctccatg atagagatgt aattttctcc agccttggtg tcctcttctg
    17521 tcagactttc taaaggattg aggacatcag ttttgacacc tgcttctttt gaaagtgtgt
    17581 tagcaagggc ttgtgaggca ttttcttcaa aatagatata ggcgatttta tttttcttga
    17641 catactctgt caattctgcc aagcgagcag ctgatggctc tgcatctgga gaaagtcctg
    17701 agattgcgac ttgtttgagt ccatagtcca aggcaagata gttaaaggct gcgtgttgag
    17761 tcacaaagct cttttgtttt gcttgagaca agccttctac gtaagcctta tccaaggctt
    17821 gcaatttttc gatataggca gctgcattct tctcaaaggt ctctttttta tcaggataat
    17881 ctgctgacaa gctgtcgcgg atgtgctcta ctagtttaat ggcacgaact ggtgataacc
    17941 aaacatgggg gtcaaactca tggtgatgac cttcttctcc atggtcatgg tccccctctt
    18001 cttcctcgcc acctggcaag agcaacatat cgcctgtcgc cttgatggtt ttcacttttt
    18061 tcttatccaa ggtatctagc aatttaggta cccatgtttc catgttttca ttttcataaa
    18121 cgaaggtatc tgcatcttgg attttggtaa ctgccttggc agatggttcg tattcatgag
    18181 gttctgtccc agcaccgatt aggagttcta cattagccgt atctcctgcg acttgcttgg
    18241 taaattcata gacagggtaa aaggttgtca cgatattgag tttaccatct gcctgttttt
    18301 gattggaaca agccactaaa aacaaggcac atagactggc tagtaataag ctaatttttt
    18361 tcacgttcgt ctcctatttg ataaaacgtc ttactaaact gattagtata aagacagtta
    18421 caaaaataat ggtaatactt gcacttgcag gtgtttctgc atagtaggaa atgtaaagtc
    18481 ctgctaccat tcccaaaaag ccaatcgcac tggcaagcag cataaccgat ttaaagtttt
    18541 tccccagacg cagggcaata ctagctggca agaccataat ggtcgatacc agaagagctc
    18601 ctgctgcagg aatcataagg gcaatagcca cccctgtcac catgttaaaa agaatggaca
    18661 tggtacgaac tggcaagcca tccacaaagg ccgtatcttc atcaaaagtt aagatataca
    18721 taggacgaag aaagagaaag gtcaaaatca aaacaaccgc cgcaatgaca aagagggaaa
    18781 tgacctgttc ttcactgata gtcacgatcg aaccaaagag atattggtcc aaactcattg
    18841 aactcgagct tttacccttg ctcatgacaa tcagagaaac agccagacct gttgacatga
    18901 ggatagctgt cccgatttcc ataaagctct tgtaaaccgt acggagatac tccagaaaga
    18961 ccgccgcaat caagacaatg gcaatagtag aaacagttgg agaaatcccc aaaaccagac
    19021 caaaggctac acctgaaagt gagacgtggc taagggtatc actcatcaaa ctctgacgac
    19081 gcaagatgag gaaggttccc aataccggtg agaaaagact catagcaata accgccaaaa
    19141 aggcgcgttg tataaagtcg taagataata aactaagcat ggctcacctc ctggccattc
    19201 tcatgaacgt tgaaacaacg ccatggcgag tcttggttac ggactagatg aatattgcga
    19261 tccgcataat ccttaacttc ttcagggtca tgggtaatca tcaaaacagc cttgccatga
    19321 tgatgggcgc tgtggtgcat gagttcgtaa aattcatttt tacttcctgc atccattccc
    19381 gttgtcggct cgtctaggat aaacacatca gggtcagaag caaacatacg cgcaattacc
    19441 gctcgctgct tttgtccccc agatagagac cccaagcgtt tgtctcgatg ttcccacatg
    19501 ccaactgagt ccagactggc cttgatatgc tcctcatcat gagcattcaa acgacggaac
    19561 cagccttttc tcggatagcg acccgacttg acaaattcat agaccgtact tggaaaacca
    19621 gcattaaaac tggcaatttg ttgaggaaga taggctattc tcaatttctt accttgcgta
    19681 tttgtctttg aaatagccac ctttccaatg cgtggttgca gaattccaag actggccttg
    19741 atgagcgtcg tcttagccgc tccattttcc ccagtcaagg taacaaattc cccactatca
    19801 acactataat tgatatgttc aagaacaggc tccttatcat aatagaagga caaatcctct
    19861 accgtaatat atctcattat ttgatttctc ctactaaagc agtcaaaaac cgctgaatca
    19921 ctttttgttc atttggagta aactgagtcg ccacttgttc ataggttaaa agtgtatgct
    19981 catggtgatg gtggtgctcc tcagcgattg gacgagccaa gtcagtcaac tgataaaaaa
    20041 tcacacgcgc atctttagaa tctttagatg tttccaacat cccttccttg accaaagact
    20101 taatggcctt ggtaactgcc gcctgactga cattgagacg acgggccaat tctgaatttg
    20161 ttaaagattc ctctgacaag agcataagga tatgctcctg agtattggtc agggccacct
    20221 cgctagtgca atgacctatt aggatttcat gctgattttc cgcctgcaaa atcacctcat
    20281 tcaaaaaagc attgatatcc tttgctagct gtctcatatc tgactccttt ccttttagac
    20341 ttctcttttt taagagaaaa atactattct ttgacatttt gtttaccagt taattatatc
    20401 acaagcaaaa aaagagtcaa gaaaaaacgt gaaaactagt ttcattcttg aactcttcta
    20461 tattatatta tctattgaaa ttctttgaca tctccatcat aagtcgccca atctttgctg
    20521 aaaaagcgct cattcagatg gtaagtcgga gctggtgtgg gattggatag gaaaggatca
    20581 actgccttgt caaaagccaa ccaacccaac caaccaaggt gaatggtgtc cttcataaag
    20641 aaaggctccc caccgtcctt agaaaaatct gctatattgg taaaaccttg actttctaac
    20701 tggtagcgaa tcttctgcac cgtttgttgg tacatatcct ctcgtagacc agcatagtcc
    20761 atccattttt tattaacagg tggaatgata aaaatcgggt ttaccttaga tttagaaaac
    20821 tgtgttaaaa ccaactgcaa gtcattatac tctggcgact tgagataggt aaagcttttc
    20881 tgagaatcct ttaatttctt caaatccttc ttgatctgct cattatagaa ataattttcc
    20941 attcccatct cattattgga agtatttttt tcagcatctg ctttgacaac atcttctatt
    21001 gcttgataag aaaactggtc tggcaagatt tttaaatact tagctacatg cttatcgtag
    21061 ttaacatagc ctctaaccga aaactgacca aaaaaggagg cttggcgttc attaaaacga
    21121 gccaataatt caatcatttc attgtctgct gtcgacaatt ctcctttact tgccaacttc
    21181 tgaaccaggt ccttcatagc tacgtttggg aactgttgca gtaagcgagt cgctgcatat
    21241 tgactagcct gatccccaga ttgatgtttc agaaaactag tcaactggtc tccattaaaa
    21301 tactgctgga aggctgctgg atcatagcca tttttactga accactgagg tgagataaca
    21361 tacacaactt gtttattctc cagctgtggt aacatctgtt gcattccaaa atattggtta
    21421 agcgatgcag ctcccccctg tcctaaaaga taaggacggt aggaacgatt gtatttctca
    21481 gctaataccg caggatgagc accgtcaaaa cgaagccatt cactagagcc aaagaaggga
    21541 acaaaacgca catttggatc agatagtgct ctgacttttt gacttcgctc cttaaaacta
    21601 tcgatagtag tagccactgc tgaacgcttt tcagctccta gattatgatg catctcagta
    21661 ggataaaaga aaatgagcag aaaaaccaac aaaccagcga tcaagaccgg tccgaagatc
    21721 atccataagc gtttaagcat tttgtagctc cacaatacca gctatgattt tattagctgt
    21781 attccagtcg tcacgaccaa actctgttac agggacacga atgtcaaaac ggttctcaat
    21841 ctccacaatc aactcaaccg ttcccatact atccaagaca cctgcatcaa aaagatcttc
    21901 atccatcatg tcagaaacat cttccataaa caactcatca ataatttcaa taacttctga
    21961 tttgatatcc atattttatt tccttttatt ttttaaacca tagattattc aagaatccag
    22021 aaaagattaa gaatgacaac atgacaacat ggaaagtgac aaccatgcca agcaactgaa
    22081 tccagcgatt ctcaggtagg gcagccttcc ctgctttttt ccgttcctta ttgagcgttt
    22141 ttttcttgcg aacccaggca tcattgatga ccaagcctag tccatgaaag agtccatagg
    22201 cgatatagta ccaggtcaca ccatgccaaa atcccataat cagcatattt acaatgtagg
    22261 ccatgcttga ggttacatta cgatttttaa agactttctt tctggttaac accatcacca
    22321 ttcgcataaa gacaaagtca cggaaccaga aggacagact catatgccag cgattccaaa
    22381 actcctttaa atcccttgat aaaaagggct tgttaaagtt gatagggcta cggattccca
    22441 tcaagtttga gatggccaaa gcaaacatag aataacctgc aaagtcaaag aagagctcca
    22501 gaccaaaagt atacataact gccaaggcat agagattaaa gaagccacct gactgcaagg
    22561 ctaaattctt cagaggaggt agtaaggtct ctcctaaaac atgagctagg ataaacttat
    22621 acaaaaagcc ccacatgata tagcggacag attcatccag catatccatc aactcatctc
    22681 gctcaggaat agcctgataa ttttcattaa atcgcttaaa gcgatcgatt ggaccactcg
    22741 agaaagttgg catgaagaga aggaaacgga ggaattccca gagggtaaaa tccttaatca
    22801 ctccatctct cagctcgatg ataatcccaa ccgaacgaaa ggtcaggtaa gaaattccca
    22861 agaacccaag caaagactgc gttccattga tagctggttg caccttgaca aagataatcg
    22921 gaagtaggga cagaaaacta actaagtaga agacccactt gccatccttg ctttttcgat
    22981 aatgcttgta gaaaagcagg agcaatattt cccagcaaag gtaaataccc aaggcagcta
    23041 gttgattggt ctttccaccc accaacatgg tgacaataaa gaagagactt accaacactt
    23101 cataccaggc aaagcgtttc ttgaaaaaga ggcctataaa gatgggcaag gttgcagcaa
    23161 tcacataaac aaaatactga ggattgccat atggctctaa atgaggaagc tgttgaaaaa
    23221 actccatcat ctcttattca cctcgttaat caatcctttg atgtcaatct ttccatttgg
    23281 agtcagtggc aaactgtctc ggtaaaggaa tttagatggc atcatgtagg acatcatgat
    23341 gtctgtcagg tcttccttga tggccttggt aatatcgata tctcgctcaa actgctcacg
    23401 aacactgtct tttaagatga cataagccaa tagattttgt accttgtggt ccttgttata
    23461 gcgcggtact gcgacagcag attcgataaa gcgagacttg ttgaggtttt gagagacatc
    23521 ttctaactca atgcggtaac cgttgaactt aatctggaag tccatgcgtc cgccgtagag
    23581 aagcaagccc tcatctgtta tggttcccac atcgcctgtg tgataggctg gcagaccttc
    23641 aaactcaaag aaggcttctg ctgttttttc aggattgttc atataacctt ttgaaacagc
    23701 tggcccagaa acaatgattt ctccctgttc gccatttggc agtttatttc cttcctcgtc
    23761 aatgataaag gttggagaat cagccttggt atagccgatt ggtaggcgtt tgagagtcgc
    23821 taacatctcg tctgtcacgg caactgctga cagagctact gtcgcttctg ttgggccgta
    23881 agcattgatg atacgggcat ttgggaaacg ctcgcgcagt ttttgagctg ttttgaccgt
    23941 caattcttca ccatcaaagt agaaatgcgt gattccaggc attttttcac tgttgaagta
    24001 ttcagacaac atggccatat ctgcaaagga tggtgttgat gtccagatag cgattggcaa
    24061 tgaaaagata gccgcaaaga gttgcttaaa gtcctgagtg atgactgaag gaagagtgaa
    24121 aagcgtacca ccaagtgcca aggtcggtgc ccaatacatg acagacaagt caaaagaata
    24181 aggtggctgt gccagcattt gcggacgact cggtgtcgca aattccttat ccgtaatcat
    24241 ccagtttgta aagctgagga gattatcatg tgaaatctgc actcccttag gcttaccagt
    24301 cgtaccagaa gtaaagataa tgtagtaatt atcatctccc ttgactggat gcgtgatttc
    24361 atagttgttc ccttgggcaa aggcttcttg aacctgagct agatttatca ttggtgtaga
    24421 aacctgctcc aagggaaagg ctgaaatggc aataatcaag cttggctctg ctacttctaa
    24481 aatagctgaa actcgctcca aggccgaatg gctatcaatt ggaatgtagg catgacctga
    24541 cttagtcagc gctacaaagg ttgccaacat ttcatattct tggccaccaa aaacaaccac
    24601 aggagacttc tcaggcaagc ctagttggtc aatgactgca gccaaactat ccgaatcaga
    24661 ctttaaatcg ccataagtgt gttcctgccc caaaacatta tagacaggat agctaggctg
    24721 tgtctgagca aaatgctcaa tggtttcaat catatctgct attggtttat ttgacacaat
    24781 agggattctc cttcaagtta aaattcatta tagataaagc ttccttgacc ctgaccaaga
    24841 tagctaaaga agtaaagcag ccctagaaag ataagaaaat acaaggctgt ccgaccaaga
    24901 aagaggtaca attcttttct ctgtttcatc aagaaaaacc attcatttct gtaatttttc
    24961 gctaaaataa gagtgattct tactagctta tttttctacc attgtaccac tttatatagt
    25021 atcttttcaa ttgtttaccg tatgtttcca atagatttca gcttatttta aggattatgc
    25081 ggtttttcta tatctatttc aaaagaaaaa agcctgagat tttcatctca agctctagca
    25141 ataatagtta ttttctaaac taaaaaagtg agaatacaag cacggccaag gctgcaccga
    25201 taacaggtcc cacaacagga atccaagcat aagaccagtc tccgtctccc ttgtttgaaa
    25261 ttggaaggat actgtgcatg atacgaggtc caaggtcacg cgcaggattc aaggcataac
    25321 ctgttgtccc acctagcgat agaccgatac cgacaatcaa ggtacccact gcaaaggttc
    25381 cgatacctgc ctgaaaatcg taaagaccca aagcaaagat tgtcaacacc aaaacaaagg
    25441 ttccaaggat ttcgctaatc aagtttgata cagtatcctt gatggctggt ccagtactga
    25501 aggttgccag gatattgcct gcattttctt ctgcctcata gtgaggtttg aattgcaacc
    25561 aaaccaaaat ctgacccagc atagcccctg cgaactgggc taagatataa ggcaaaacgg
    25621 aagcccaagg caagtcacct tttaaagcta caccaattgt cacagctgga tttaaatgag
    25681 ctggactgag cttgccagat acaaatactg caaccgcaac tgcaatcccc caacccatag
    25741 taatcacaat ccaacctgag ctattgctct tggttttagg aagaaccaca cctgcaacaa
    25801 caccatttcc tagaagaatc aggattaaag tccctagaaa ttctccaaat aattcattca
    25861 tcatctttct gtctccatta aaaagaaggg acgagcgaca aggaatgctg ccctccacct
    25921 cttttatttt ttcttaattt tttaattctg ctaaatcgtt gttagcgaga gctgcttcga
    25981 catcagcacg gtaagttgct ttttcttctt ctgtccagtc atagaatcgt cccatttcat
    26041 ccaaaactgg ctcaacgatg ctatccaagc tatcacgcat aaagagcata tggttggtac
    26101 gacgaagaag gaagtcaact gggctaagag ccaactcgtt gcgcattgca tagtgaaggg
    26161 acaaagtatc tgccaagctg agtcctggcg cttgttccaa gctgtgagca agtgcaaaga
    26221 ctttcggtgc atttgaaccg taaagatttg ccagatagtg agcttccttg ctatccaaac
    26281 cacgtgatac tccaagttgc gcaaaggctt cgatttctga atccacattt gctgggttca
    26341 attctccacc tgaaacaggg taagttttag aattgatcaa tttaaagcta cggtcaaatt
    26401 ctgctttgag gatgtcaacc acgcgctcca tagctccttc agccatctta cggtagtctg
    26461 tgattttacc gccagcaaga gtcaaaagac cattgtcatc acggtccaag ctagacccac
    26521 gagaaactgc agatggatcc aaatatttct cagatgtgct actttcaagc ttgctgacag
    26581 cagactcaac atcttcacgt gttttttctt tggagagata agattcaaca gtcgcaatca
    26641 agttgtcaaa gctttcatca ctgatggtac cgttatttcc accattatag tcagaggcac
    26701 tgttccctgc aatcaatgga cgaagacctg cccagctgct ttcgatatca tcaatggtga
    26761 tgttggattc tggaaagcgg ttgttgacaa tgccaagtag ataatctaca tcttcttgag
    26821 ttacttttgg atgctccaaa tcacctgtgt agtctgtatc agttgtacca aagtaagtct
    26881 tgttttcacg tgggagaaca aagaccatac gaccgtcacc caaacctgtg tcgaagtaaa
    26941 ctggctgtga aaccttgatt ttgcttgaat ccactaccaa gtgaactccc ttagttgggc
    27001 gcatttgtga gaattgcgtt cccttattag acaaattacg tactttatca ctccaaggac
    27061 ctgttgtatt aataaccaga cgggccttga tttcaaatac ttggtctgtc aagagatcac
    27121 gagctacaac acctgtaatc ttgccacttt cgtcaaagag gaagccttct gccttcacgt
    27181 ggttggcaat gagggcaccg tcttggttgg cacgtttgat gttttcaatc acgagacgcg
    27241 catcgttgtt acggaagtca agatacactc cacctcctac caagccttcc ttcttcaagt
    27301 ttggctggcg ttccaagact tgatccttgc tcaaaacctt gttcgcagct gacgtgttgc
    27361 tcacacctgc taaaaggtcg tacaagtcca tggctacttt aagacggaag aggctaaagg
    27421 ttgctccatc ttcatcgtaa actggtaaga gcattggatc tgattttgga atgtgtggag
    27481 cgatttgttg aaccactgca cgttcagaaa ccgtatctga gaccacttct acgtcaaatt
    27541 gtttgaggta acgaagtcct ccgtgaacca attttgttga acgactagat gttccttctg
    27601 caaagtcttg catttcaatc aaaccagtct caagaccgct agctgccgcc tgcaaggcta
    27661 caccagctcc tgtgattcct ccaccgataa tcaagaggtc cagggtacgt tcctgcattt
    27721 ttttaattga caattcacgt gttttctttg aaaattccat atttacacac tttctaaata
    27781 aatcgcttta ttctgccagt attagtcgtc tacttccgca aagacttgag ttgctttcac
    27841 agccttcttc cagcccttgt agagttgttc cttgcgagat tcgttcatag atggctcaaa
    27901 gagttctcct gtctcgttca agagtttcaa ctcgtccaag tctttccagt accctactga
    27961 caaacctgct aggaaggccg ctcctagagc tgttgtttcc aggtttttag cacgtgcaat
    28021 gtcaatgcct aaaatatccg cctggaactg catgaggaag ttgttcatgg ctgcaccacc
    28081 atccaccttc agtacttgaa tggcggtctg agtatccact tgcatggtgt cgatgatatc
    28141 acgcacttga taagcaatag attgcaaagt cgccttgata aagtcttctt tgcttgttcc
    28201 acgagtcaaa ccaaagacgg aaccacgagc attttggttc cagtatggag cgcctagacc
    28261 tgtaaaggct ggaacgacat aaacttcatc gttgttgtga gaatcacgag cgtatttttc
    28321 agattctggt gaattttcaa ccatgcgaag accgtcacga agccactgaa tagcacttcc
    28381 tgcgatgaag atagaacctt ccaaggcata ataaacctta ccgttgattc cgtaaccaat
    28441 ggttgtcaag aggttgtttt cagacaactg catctcttcc ccagtattca tgatgatgaa
    28501 agagcctgtt ccataagtat tcttaaccat acctggctca aaagccaact gtccaaagag
    28561 ggctgcttgt tggtccccag ccatacctga gattggcacc tctccaccgt agaaatggaa
    28621 tggagctgtc ttgccgtaga tttcggagtt agaacgaact tctggaagta tagccttcgg
    28681 aatgttaagg atttccaaaa tctcatcatc ccatttgagt tctttaatgt tataaagcat
    28741 ggtacgagct gcatttgagt agtcagtcac gtgagccgca ccgtcagtca atttccaaac
    28801 caaccaagta tcgatagtac caaagagcaa ttcccctttt tctgctcgct cttgagcacc
    28861 ttctacatga tccaaaatcc aacgaacctt ggtagcagag aagtaagcat caataatcaa
    28921 accagtcttt tcatggaatt tttccacata accttggctt tttagttgct cagccaaagg
    28981 tgctgtctgg cgtgactgcc aaacgatagc attgtagata ggaagtcctg ttttcttatc
    29041 ccagacaacc gttgtttcac gttggttggt aatcccgatt gcctcgattt gatttggctt
    29101 gacaccactt tcgatgaaag cacccgcaat aactgactga acagagttcc aaatttcatt
    29161 ggcattgtgc tcaacccaac ctgcctgagg gaaaatctgg gtaaactctt tttgactcga
    29221 gctaaccttt tccccttttt tgttgaaaat gatggcacga gaacttgtag ttccctggtc
    29281 aatggccatg atgtattttt cttgtgacat gtactgtcct cctgataaag atcttgaggt
    29341 gtttcctctt tacacttact agtatacaaa ataaagcgct ttcttgttta tcaacttttt
    29401 ttaattttta aaaaaatgtg aggagattgt gtgaatttca caaaaaagac ctggattaac
    29461 caagcctttt aagtgaataa taactggcga atcgctacca aatcctccat atccaagtca
    29521 ttttttaaat aatagactgg tgtctgttcc ttcttatgaa tcgggttatt ggtaaccagc
    29581 aaatcataat gccgactagg gtcataagct tcaatggtaa taaaacgatt gtattccaaa
    29641 taccgtttca aaatggctgc catccttgaa aagacaagaa aaccagatgt caaatccaga
    29701 ccaatccgca tatgctggcc accgttttca gccatatatt cgattaactg gagccattcc
    29761 cagagaatct tcttatctaa atctgtcccc tgttgaaaag taggtagagc atgaaaaatc
    29821 tcctctgctg tctctttaaa atcatgttcc atcagtaaat atggatgacg attctctaac
    29881 tggtacttgt agcgatcctg taaaatatag cccttataga gatagacttg agcacaaagc
    29941 tgactgagtt cataggtgac atggtcctct gtataatccc ccaatagttc ctccttcttc
    30001 atttcttgaa tcaattgcgt cagtaaatct gccaactgcc ctccaaaacc aagaatatac
    30061 tccatagtat gaagaggaag aatgcgatga gataggagaa aagagaagaa tatcatcatc
    30121 tcaccatcct caactcctag tggaatatgt tgcccagcaa aaaaggacgg aacctttctc
    30181 agcaaacgaa gataaaagat attgtcaaaa taccctcgca ttttctcttc tatgacttga
    30241 aactgacaag cattgacccg aagacgttgt tgactgatgt gagcccagag aaccaagtcc
    30301 aatttctgcc ccacagacaa acttgcaccg cagatttcct ctaaattggc aatctcctgt
    30361 tttctctctg gtttctgcat gtgaccttcc cattcctgac tcgaccagac ctttcggaaa
    30421 agacagaaat agaaatagcg aatctgatgc tctggacctc gccaacgtcc attttggatg
    30481 gataaatcaa attctgacag aatctgattt aaaccagcca agtgacgacc aagcgtagcc
    30541 tcgctaatca ccaattcttg agccagctga tgggctaaaa actgttggtg gtagagaaga
    30601 taaaccaaaa tctggtattt aacagcactc tccaaaaata agctccgaat atctctcccc
    30661 ttggtagctg caccgataga cagacgcaaa ttttcatttt ctgagtgaat agtcagctct
    30721 aagccactat ccaaagcctt gtcattgagc agggtgacat atttggttag ggttgctttt
    30781 gaaaatcctg tttcttccat tacagccttg acggtcgtct gagactcttg taatagaaag
    30841 gaaaggattg aaaattgacc acactcagct ttctccatca aatctcctaa atacatttgt
    30901 tacccctttc attttctacc ttaagcatag cataaatctt acaaatgctg aaataatctg
    30961 tttctctttt tattttcatg ctgatttcct ggtccattat cctgaaaatc agtaaacaca
    31021 cggctccccc tctgggcatt tttatgctaa aatagtagct atgaataaaa ttattaaaac
    31081 tatatcagaa agcggagcct ttcgtgcttt tgtccttgac agcacggaaa ccgtccgcac
    31141 tgctcaagaa aaacaccaaa cccaagctag ctcaactgta gcgcttggtc gaactcttat
    31201 cgctagccag attctcgcag ccaatgaaaa aggaaatacc aaacttacag ttaaggtgtt
    31261 gggatctagc tctctaggtg ctattatcac cgtcgctgat accaagggga acgtcaaagg
    31321 ctacgttcaa aatcctggtg ttgacatcaa aaagactgcg actggtgaag tcctagtcgg
    31381 accttttgtt ggaaatggtc aattcctcgt tatcacagac tacggtactg gaaatcctta
    31441 caactctata actcccctca tctccggaga aatcggtgaa gaccttgcct tttaccttac
    31501 tgaaagccaa caaacgcctt cagcggtcgg cctcaatgtc cttttggacg aggaagacaa
    31561 ggtcaaggtt gcaggtggtt tcctagttca agtcttgcca ggagccaaga aagaagagat
    31621 tgctcgcttt gaaaaacgca tccaagaaat gccagctatc tctactcttc tcgaaagcga
    31681 cgaccatatc gaagccctcc tcaaggctat ctacggggac gaagcctaca agcgtctttc
    31741 tgaagaagaa atccgtttcc aatgtgactg tagccatgaa cgctttatga acgctcttgc
    31801 cagccttcca agctcagact tacaggaaat gaaagaagaa gaccacgggg cagaaatcac
    31861 ttgtcaattc tgccaaacta cttacaactt tgatgaaaag gacctggagg aactcattcg
    31921 tgacaaatct taatacacct tttatgattg gcaatgttga gattcccaat cgtaccgttt
    31981 tagcgcctat ggctggcgtg accaactcag cctttcgtac catcgcaaaa gagctcggag
    32041 ctggactcgt tgtaatggaa atggtctctg acaaaggaat ccaatacaac aacgaaaaaa
    32101 ccctgcacat gcttcatatc gatgagggcg aaaaccctgt ctctatccaa ctttttggta
    32161 gcgatgaaga cagcctagca cgcgcagcag aattcatcca agaaaacacc aagaccgata
    32221 tcgtcgatat caacatgggc tgccctgtca acaaaatcgt gaagaacgaa gctggagcta
    32281 tgtggctcaa ggatcctgac aagatctact ctatcatcaa caaggttcag tctgtccttg
    32341 atatccccct tactgtcaaa atgcgtaccg gatgggcgga cccatctctg gcagtagaaa
    32401 atgccctcgc tgctgaagct gcaggtgttt ctgccctcgc catgcatggc cgtacccgtg
    32461 aacaaatgta tactggccac gcagaccttg agacccttta caaggttgcc caagctctaa
    32521 ccaagattcc attcatcgcc aacggtgata tccgtactgt ccaagaagcc aagcaacgca
    32581 tcgaagaagt tggtgctgac gcagtcatga ttggccgagc tgccatggga aatccttacc
    32641 tcttcaacca aatcaaccat tactttgaaa caggagaaat cctacctgat ttgacctttg
    32701 aagacaagat gaagatcgcc tacgaacact tgaaacgatt gattaacctc aaaggagaaa
    32761 acgtcgccgt tcgtgaattc cgcggcctcg ctcctcacta tctccgtgga acatctggcg
    32821 ctgccaaact ccgtggagcc atttcacaag ctagcaccct ggcagagatt gaagctctct
    32881 tgcaattgga gaaggcttaa tagtttaaaa cccgtaactc tcttaaagag tctcttgagt
    32941 gccgccattc tttcctcatc aaaaaaactc cgtagtctct agcgccataa atccggctag
    33001 agattacaga gttatttttt aatctaaact tcctacaagg gtatagtatc tactgaaagg
    33061 atatggtatt tgtagggaat actttaaaga gttcttacag gaagccagca ttaacgagtt
    33121 acattaggtt tagtttaccc atttaccatt ggcattgact ctatagccac ctacagttgt
    33181 gttgactgca agggcacctg agccattgac atagtaccat ttgtctgata ctttgaacca
    33241 ttggctttct ttcatagccc ctgatgcttc aagatagtac catgtatctc catctttcag
    33301 ccaacctgtt gccatcgaac cgttagcatt
//
LOCUS       DBERAE010000021        32835 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.21, whole genome shotgun sequence.
ACCESSION   DBERAE010000021 DBERAE010000000
VERSION     DBERAE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.21"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(322..1170)
                     /gene="dprA"
                     /locus_tag="ACL70N_001158"
     CDS             complement(322..1170)
                     /gene="dprA"
                     /locus_tag="ACL70N_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGS0589966.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1266..1955)
                     /locus_tag="ACL70N_001159"
     CDS             complement(1266..1955)
                     /locus_tag="ACL70N_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGS0589967.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEIFKNEN"
     gene            complement(1967..2845)
                     /locus_tag="ACL70N_001160"
     CDS             complement(1967..2845)
                     /locus_tag="ACL70N_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0589968.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2835..3704)
                     /gene="licA"
                     /locus_tag="ACL70N_001161"
     CDS             complement(2835..3704)
                     /gene="licA"
                     /locus_tag="ACL70N_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGS0589969.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIEFAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3721..4743)
                     /locus_tag="ACL70N_001162"
     CDS             complement(3721..4743)
                     /locus_tag="ACL70N_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGS0589970.1"
                     /translation="MINQIYQLTKPKFINVKYQEEVIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4748..5455)
                     /locus_tag="ACL70N_001163"
     CDS             complement(4748..5455)
                     /locus_tag="ACL70N_001163"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGS0589971.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLHKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5791..7278
                     /gene="tacF"
                     /locus_tag="ACL70N_001164"
     CDS             5791..7278
                     /gene="tacF"
                     /locus_tag="ACL70N_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGS0589972.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7288..8091
                     /locus_tag="ACL70N_001165"
     CDS             7288..8091
                     /locus_tag="ACL70N_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0589973.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8093..8902
                     /locus_tag="ACL70N_001166"
     CDS             8093..8902
                     /locus_tag="ACL70N_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0589974.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9177..12353)
                     /gene="carB"
                     /locus_tag="ACL70N_001167"
     CDS             complement(9177..12353)
                     /gene="carB"
                     /locus_tag="ACL70N_001167"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGS0589975.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12666..13745)
                     /locus_tag="ACL70N_001168"
     CDS             complement(12666..13745)
                     /locus_tag="ACL70N_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGS0589976.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13795..14718)
                     /locus_tag="ACL70N_001169"
     CDS             complement(13795..14718)
                     /locus_tag="ACL70N_001169"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGS0589977.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14737..15258)
                     /gene="pyrR"
                     /locus_tag="ACL70N_001170"
     CDS             complement(14737..15258)
                     /gene="pyrR"
                     /locus_tag="ACL70N_001170"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGS0589978.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15469..16098)
                     /gene="nth"
                     /locus_tag="ACL70N_001171"
     CDS             complement(15469..16098)
                     /gene="nth"
                     /locus_tag="ACL70N_001171"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGS0589979.1"
                     /translation="MVLSKKRARKVLEEIITLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16098..16640)
                     /locus_tag="ACL70N_001172"
     CDS             complement(16098..16640)
                     /locus_tag="ACL70N_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGS0589980.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16810..17127
                     /locus_tag="ACL70N_001173"
     CDS             16810..17127
                     /locus_tag="ACL70N_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS0589981.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            17366..18925
                     /locus_tag="ACL70N_001174"
     CDS             17366..18925
                     /locus_tag="ACL70N_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0589982.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18969..19868)
                     /gene="htpX"
                     /locus_tag="ACL70N_001175"
     CDS             complement(18969..19868)
                     /gene="htpX"
                     /locus_tag="ACL70N_001175"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGS0589983.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19870..20430)
                     /locus_tag="ACL70N_001176"
     CDS             complement(19870..20430)
                     /locus_tag="ACL70N_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGS0589984.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20524..21237
                     /gene="rsmG"
                     /locus_tag="ACL70N_001177"
     CDS             20524..21237
                     /gene="rsmG"
                     /locus_tag="ACL70N_001177"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGS0589985.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21491..22774
                     /locus_tag="ACL70N_001178"
     CDS             21491..22774
                     /locus_tag="ACL70N_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGS0589986.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(22969..24540)
                     /gene="ffh"
                     /locus_tag="ACL70N_001179"
     CDS             complement(22969..24540)
                     /gene="ffh"
                     /locus_tag="ACL70N_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGS0589987.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(24552..24884)
                     /locus_tag="ACL70N_001180"
     CDS             complement(24552..24884)
                     /locus_tag="ACL70N_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGS0589988.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(24975..25352)
                     /locus_tag="ACL70N_001181"
     CDS             complement(24975..25352)
                     /locus_tag="ACL70N_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGS0589989.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            25424..26728
                     /locus_tag="ACL70N_001182"
     CDS             25424..26728
                     /locus_tag="ACL70N_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS0589990.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            26741..27547
                     /gene="yidA"
                     /locus_tag="ACL70N_001183"
     CDS             26741..27547
                     /gene="yidA"
                     /locus_tag="ACL70N_001183"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGS0589991.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(27602..27673)
                     /locus_tag="ACL70N_001184"
     tRNA            complement(27602..27673)
                     /locus_tag="ACL70N_001184"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27638..27640),aa:Arg,seq:cct)
     gene            complement(27715..28062)
                     /gene="rplS"
                     /locus_tag="ACL70N_001185"
     CDS             complement(27715..28062)
                     /gene="rplS"
                     /locus_tag="ACL70N_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGS0589992.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(28181..28510)
                     /gene="crcB"
                     /locus_tag="ACL70N_001186"
     CDS             complement(28181..28510)
                     /gene="crcB"
                     /locus_tag="ACL70N_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS0589993.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(28504..28878)
                     /gene="crcB"
                     /locus_tag="ACL70N_001187"
     CDS             complement(28504..28878)
                     /gene="crcB"
                     /locus_tag="ACL70N_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS0589994.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(28875..29141)
                     /locus_tag="ACL70N_001188"
     CDS             complement(28875..29141)
                     /locus_tag="ACL70N_001188"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGS0589995.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(29257..29700)
                     /locus_tag="ACL70N_001189"
     CDS             complement(29257..29700)
                     /locus_tag="ACL70N_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGS0589996.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            29804..30739
                     /locus_tag="ACL70N_001190"
     CDS             29804..30739
                     /locus_tag="ACL70N_001190"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGS0589997.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            30835..31077
                     /locus_tag="ACL70N_001191"
     CDS             30835..31077
                     /locus_tag="ACL70N_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGS0589998.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(31134..31712)
                     /locus_tag="ACL70N_001192"
     CDS             complement(31134..31712)
                     /locus_tag="ACL70N_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGS0589999.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(31687..32700)
                     /locus_tag="ACL70N_001193"
                     /pseudo
     CDS             complement(31687..32700)
                     /locus_tag="ACL70N_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(32703..32835)
                     /locus_tag="ACL70N_001194"
                     /pseudo
     CDS             complement(32703..32835)
                     /locus_tag="ACL70N_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9835 a         7174 c         6067 g         9759 t
ORIGIN      
        1 tttcccttat actcaatgaa aatcaaagcg caaactagga agctagccac aggttgctca
       61 aagcactgct ttgaggttgt agataagact gacgaagtca gctcaaaata ctgttttgag
      121 gttgcagatg gaagctgacg tagtttgaag agattttcga agagtattat atgagaaaaa
      181 tcctctactc tactaatcca cttagaaaaa acgcatatta tcaagtgtta aaaacttgct
      241 aatatgcgtt ttattatgga aatgttgggt tcattttctc ttaaaattga ttttttctta
      301 gaattctagc ttaggtcatt tttaaaattc aaattccgca agaacatctt gcccactggt
      361 gaccaatttt gctccttctt gaatcaaatg atggcaaccg tctgatagtc catctaaaat
      421 gctatcagga atagcaaaga catcgcgtcc ttcttccatt gctcgctcac acgtaatgag
      481 actacctgaa cgcatcttag cctctgctac aatcacacca cgacaaagtc cagcaatgat
      541 gcgattacgg gcaggaaaat gaaatttcag aggttgttcg ccaggtccat attcacttag
      601 aaccagatgg tcattgccga tgtagtcttg caagcgttta ttggctttag gataaaacac
      661 atccagtcct gttccaatca ctgcaatggt ttttccgcca ttctgaagag ctgccatatg
      721 agctgctgtg tcaatgccct tggccagacc actgacaata accagttcat tttccaagcc
      781 ttgaatgact ttttcaactg acttagctcc ctgtttgcta caagcacgac tgcccacgac
      841 cgctaccttc gggaatttca ggaggtcaag atttcccttg taaaataaaa gtacaggcgc
      901 atcatatatt tcactcaaat cccaaggata acagtcatct aaaatagaga aagatggaaa
      961 tttttgaaac tctttcgaca aatgcgcatc gtctatctga aaataacgtt ccataaaaac
     1021 ggctggatta cggcaacctg atatatctgc aatatcaccc aacaaaagct cctgatcaac
     1081 attttcaccg tattctagaa ctttcaaaat ctgttgattg gtcaaacttg atttttttaa
     1141 cttatagatt tcatagtttg tgattttcat aaataactcc atttcttttt ctactcatct
     1201 atctattcgt aaaagttcgt aaaaaatcaa aaaacatccg actattttgt cagatgttgg
     1261 aatctttaat tttcgttttt aaaaatttct tctaatttac gatagtcttg gacactatcg
     1321 atctcataaa tgctattgcc ttctaattct tcaacataga catctagctc tttgatatta
     1381 tccttaacca tattgtccca atagagatca acaaattcgc cacttgcata agccttatcg
     1441 ataaagctga caatcttttc tgcagttgga gcatcccaga aggatacacc actaaggatg
     1501 cgacctgcct tgctatcaac aataatgtct tgaaccttgt agtcatctcc atagaccaag
     1561 aaccattcgt tggtacaatc ttcacgataa acactaaaat aagtcgaacg agtcaaatca
     1621 ttgcggaaca tatttttaaa gagataattg tcagcatcaa taacatagct gttggccaat
     1681 tcttctttta caagatagag agagtaaaag ttattgtagt cagcgtattt atcattgaaa
     1741 acgaggcgaa caccgtattt ttcttttaag taatcgaatt gttctttaag ataaccaaca
     1801 atgatgatga tgtcattgat tcctttttct ttgagaaact caatttggta ctcaattaag
     1861 ggtttttgat taacctgaac caaggcttta ggggtatttt cagtcatagg acgcaagcga
     1921 gttcccaatc ccgctgctaa gataatggct ttcacacgaa tctcctttat tctttaataa
     1981 taatataaac tccagcaatg acgacaagtg acgtcataat ggtcagcata tctagcggtg
     2041 cacccaagaa aacaactgca aacaagaccg tccatactac atagctcacg ttcaagcctg
     2101 tagccttggc tggttgcaag cgattgatag cgatataata agccaagtag gaaatcatat
     2161 caaaggctgc aaaaacaatc atgagaccta gcaattgtcc attggctact gcagtaaatg
     2221 actgatgaga gaagagcaca atcacaagat aggacaagaa cgaagttact tgacggatta
     2281 agagggcttc gatttcactc aattcacttt ccatggcaaa agagctaaga acactctcac
     2341 ttccccatgc aatagcacaa accaaagcac aaagaatccc aatgtagaaa gaattaacct
     2401 gttcaacctt ataggtctga gcaataatcc ctccaataat caagacaatc ccaaatacag
     2461 tatttttcga aatcttgtgc ttcaaaaaga agaaagccaa tagaactgaa atcgcagggt
     2521 aaatagccga tacagatgaa gctaaagaac ttccgatata cttaactgca taaagattgg
     2581 cctgcatacc gatagggcct gctagcaagg ctccgatgat aacactgaca ttgcgaatat
     2641 ttaagaaaat tgagaggcga actttccctt cttttaccaa gagaaaagct agtaagataa
     2701 agatgctcaa aaaatcatga gctgcagcca ccacaaaggg tgacaaatct gtaaaaatcg
     2761 aaaagatata agcactaacc gttagaccca agccccagaa aatacctgag agaaggccaa
     2821 aaggaactcc gtttttactt ttcatctgaa cctccataag aagccaaacc tttaacagct
     2881 ctttggtaac gattcacacc atagtcacca aaatcttcac cttgctcttc cttatagaca
     2941 gtccatagac tccaaatagt atcttgtaaa attttataaa tagcaatctt ttcatgagaa
     3001 accggtgttt ggtcactctc atagtgagat aagaaagttt cttcctcttg ggaagtgaat
     3061 tcagactcta aaaagagggc agccaaatcc cacattggat cattcattga tgaatattcc
     3121 cagtcaatca aataaagtcg tccttgaggt gattcgataa agttttcagg caccaaatcg
     3181 atatgacaag attttctgtc aacacctaag tcagccagtc ttttctctaa ggagaagact
     3241 gcatttctaa cagattcata gttggcataa ggaatttgtt cttcaatcaa ggattcgtat
     3301 tttttgattt cttcaaaagg agcaaattct cctcttaatt ccttagcaga cgtatgaata
     3361 gtttgtaata ttggagcaat tttgtcgaac ttggtcttga ttgacgttga atcaagcgta
     3421 atcgcaaatt cgatatactc atttactttg ataccagctt caatatcaaa aagataattt
     3481 tttacatcta agcctaaatc ctttagtagt tcaagattgt acttttcatc ttgtcgattg
     3541 ataagctttt ctgtcccttt accaaagaat ttaacaatgt attgcttatt tgttgttttg
     3601 gccaaatagt tttgattggt cattccaccc agttgttcaa cactgaggac ttcctcttct
     3661 tgactaagta aggaagaaat tttttcttta atgattttct ccacaattaa cctccagtac
     3721 ttatacttcc cacttaaaca ctgttttaaa ggctgtgttt aaatcggttg caaagacacg
     3781 atgaatatct ttaatttctc ttacaggttc ttctagataa aggatatttt taagacgatt
     3841 ggcaaatttc ttgacttcca tcatttggat agcattttca aaatcaatgc gaccagaacg
     3901 agatgaccca accaaaatca agcccttttc taaggcatcg cgagtattga gattgacttt
     3961 atattcgcta actcccatca tgagaatcgt tccctgagga cgaatgtagc gaatcaagtc
     4021 attaatagct ggtccagtac catcaccacc acaacattca aaagcatggt caaaggccaa
     4081 atcttcagga atattatccg taatatagca ttctttggca aatgagaaga gttccaactt
     4141 ttcccaatga cgaccaataa ccacaatctc tgcttctggc aaagtatagt tgataatatt
     4201 ggcaaccaca aaagctaaac ttccatctcc aataacggcg atccgctccc gcttgctatg
     4261 agcaagagtc aatagacgat tcatagcgtg catgcccaca ctgacaaact ctgtaatggc
     4321 tgcaaccgta tcttcaatag catcataagc caccacacga tctttaggga gagaaacaaa
     4381 ctctctcata aagccatcaa atccactaga caagaaatgg gtccctgtca tgtagttttc
     4441 atagaattct tcatcactct gcataggaga ctgattggga atcatgacaa ctttttgacc
     4501 aacctcgtag gttccggtcg ggtcagaaat gacggttcca catgactcgt gaatcattgc
     4561 cattggaagc tttttattca aaatcttggg atcacgtttt ccctgatagt aacgctgatc
     4621 cgcatgacag acagccatgt agttgggacg gataaggata tgattctctt ggtcaataac
     4681 ctcttcctga tatttgacat tgataaactt aggcttagtt agttgataaa tttgattaat
     4741 cattttacta gtctttctca atcatacttt ttgcaatctt caaatctgtt acggttgtaa
     4801 tcttcagatt tgagtattca cctttggcca aggccacatc ttttcctttg atcacaaaga
     4861 ttttacatgc atctgtcaag atttccttct cttcatcaga aagagatcca taaaggtcca
     4921 tgaagtcctt gcaacggaat gtttgaggtg tttgtccttg ataaaggtga gcacgatttg
     4981 gaatatctgt aataaattga ccattggtac tttcaacgat agtatcaacc gcttctacca
     5041 ctgtgtccac tgcgtcatga ttttgggcaa gttggatatt gtcctgaatc atgcgaagtg
     5101 taataaatgg acgaacagaa tcgtgggtaa caacgatatc ctctgaagta agcggacgat
     5161 aagcatcaat ggcttcaatg attttctcaa tacttgtatt gcggtcagca ccaccctttg
     5221 taatgatgat acgttccttg tgaagaggaa gatatttatc tacaagatct tctgcatgag
     5281 aaacccagtc tccatgaacc ccaactacaa ttttttcaat acttggctcc aagacaaatt
     5341 tttcaattgt atgaatcaaa ataggtcgat cacctagctc taaaaattgt tttggcaagt
     5401 tactgattcc catgcgtgtg ccagttccac cggcaagaat tcctgcataa atcatctatt
     5461 ttctcctttg tcttactaaa aaaacttatt ctctctatta taccacaatc tagtcctatc
     5521 ataaaagaaa tactggtcct ccccttctag aataggagaa ttatgcagtt ctattattca
     5581 aagaaactag ttcatttcta gtaatgacta ggaattctgt agcaattact aataaatggc
     5641 tgcgaaattt tagagtcctt cagaataata tactttcctt aaagaaaact taaaatttaa
     5701 gatttgaaac ttcaaagtga ttacttgact tactgccctt catttcttat tagctaactt
     5761 tatgatataa tgaaaaacga ggtaaattga atgaaaagta taaaattaaa tgctctatct
     5821 tacatgggaa ttcgtgtctt gaatattatt tttcccatcc taactggaac ctatgtcgcg
     5881 cgtgtcttgg accgaactga ctatggttac ttcaactcag tcgacactat tttgtcattt
     5941 ttcttgccct ttgcaactta tggtgtctat aactacggtt taagggctat cagtaatgtc
     6001 aaggataaca aaaaagatct taacagaacc ttttctagtc ttttttattt gtgcatcgct
     6061 tgtacgattt tgaccactgc tgtctatatc ctagcctatc ctctcttctt tactgataat
     6121 ccaatcgtca aaaaggtcta ccttgttatg gggattcaac tcattgccca gattttttca
     6181 atcgaatggg tcaatgaagc tctggaaaat tacagttttc tcttttacaa aactgccttc
     6241 atccgtatcc tgatgctggt ctctattttc ttatttgtta aaaatgaaca cgatattgtt
     6301 gtctatacac ttgtgatgag tttatcgacg ctgattaact acctgattag ttatttttgg
     6361 attaaaagag acatcaaact tgttaaaatt cacctaagtg attttaaacc actctttctc
     6421 cctctgacag ccatgttagt ctttgccaat gccaatatgc tcttcacttt tttagatcgc
     6481 ctcttcctcg ttaaaacagg gattgatgtc aacgttagtt actataccat agctcagcga
     6541 attgtgaccg ttatagctgg ggttgtaaca ggtgcaattg gagtgagtgt gcctcgtctc
     6601 agttactatc tggggaaagg agacaaagaa gcctatgttt ctctggttaa tagaggtagt
     6661 cgaatcttta acttctttat cattccactg agttttggac tcatggtttt aggaccaaat
     6721 gccatcctac tttacggtag tgaaaaatat atcggaggcg gcatcttgac ctctctcttc
     6781 gcttttcgta cgattatcct ggccttagat accattcttg gttcccaaat tctctttacc
     6841 aatggctatg aaaaacgtat cacagtctat acagtctttg ctgggctact caatttgggc
     6901 ttgaatagtc tcctcttttt caaccatatc gtggctcctg aatactactt actgacaact
     6961 atgttatcag agacttctct acttgttttc tatatcattt tcatccatag aaaacaactc
     7021 atccacttgg gacatatctt tagctatact gttcgatact ctctcttttc actttccttt
     7081 gtagcaattt atttcctgat taatttcatg tatcctgtgg atatggtcat taatttgcca
     7141 tttttgatta atactggttt gattgtcttg ctatcagcta tctcttatat tagtctactt
     7201 gtcttcacaa aagatagcat tttctatgaa tttttaaacc atgtcctagc cttaaaaaat
     7261 aaatttaaaa aatcttagga gtttaaaatg aaacaactaa ccgttgaaga tgccaaacaa
     7321 attgaattag aaattttgaa ttatattgat actctctgta aaaagcacaa tatcaactat
     7381 attattaact acggtactct gattggggcg gttcgacatg agggctttat cccttgggac
     7441 gacgatattg atttatccat gcctagagaa gactaccaac gatttattaa catttttcaa
     7501 aaggaaaaaa gcaagtataa gctcctatcc ttagaaactg ataagaacta ctttaacaac
     7561 tttatcaaga taaccgacag tacaactaaa attattgata ctcgaaatac aaaaacctat
     7621 gagtctggta tctttatcga tattttccct atagatcgct ttgatgatcc taaggtcatt
     7681 gatacttgtt ataaactgga aagcttcaaa ctgctgtctt tcagtaaaca taaaaatatt
     7741 gtctataagg atagcctttt aaaagattgg atacgaacag ccttttggtt gctccttcga
     7801 ccggtttctc ctcgttattt tgcaaataaa atcgagaaag aaattcaaaa atatagtcgt
     7861 gaaaatgggc agtatatggc ttttattcct tcaaaattta aggaaaagga agtcttccca
     7921 agtggtacct ttgataaaac aatcgattta ccctttgaga atttaagcct tcctgcacct
     7981 gaaaaatttg atactatttt gacacaattt tatggagatt atatgaccct accaccagaa
     8041 gaaaaacgct tctacagtca tgaatttcac gcttataaat tggaggatta ggatgcaata
     8101 tttagaaaaa aaagaaatta aagaaattca actagccctg ctggactata ttgatgagac
     8161 ttgtaagaaa catgatattc cttattttct cagttatgga accatgcttg gagccatccg
     8221 ccacaaaggt atgattcctt gggatgatga tattgatatt tccctttatc gtgaggatta
     8281 tgagcgttta ctgaagatta ttgaagaaga aaatcaccct cgctacaagg ttctttccta
     8341 cgatacatct tcttggtact tccataattt cgcatcgatt ttggacactt ctactgttat
     8401 agaagaccat gttaagtaca agcgtcatga taccagcctt ttcatcgatg tcttcccaat
     8461 tgatcgattt acagacttga gcattgtcga caagagctat aagtatgtgg ctcttcgtca
     8521 actagcttat atcaaaaaat cacgagcagt tcacggtgat agcaaactaa aagattttct
     8581 tagattatgt agctggtacg ctctccgatt tgtcaatcct cgctactttt acaagaaaat
     8641 tgatcaacta gtcaaaaatg ctgtaaccaa cactcctcaa tatgaaggag gagttgggat
     8701 cggtaaggaa gggatgaaag aaatcttccc agttgatacc tttaaagaac tgattttaac
     8761 tgagtttgag ggccgtatgt tgcctgttcc caaaaaatat gaccaatttt taacccagat
     8821 gtatggcgat tatatgacac caccatcaaa agaaatgcaa gagtggtata gtcatagcat
     8881 taaagcttat cgcaaaaact gattgagggg tattatacaa actactaaga tagaggttat
     8941 tcaaaaacat aattttagta gaaaatgaaa tacatattcc cacaataaaa cgcatcatat
     9001 caaggttttt gaaaaacctt gatatgatgc gttttataat tttaaagact tttttctata
     9061 gtagattgaa ataagatgcg aacgaatcaa ttagaaaatt caaattaatt tctagaaata
     9121 ttttagtatc cctgtgtact gttctaaatt cagtctgcta tatcttattt ttctatttaa
     9181 atcgcttctg taacaaagct acgactttca agtaccttaa gcatggcatt agctgtatct
     9241 agcgctgtga agaggggcac cccgtgttca atggctgaac gacgaatttg ctcaccatct
     9301 tcgtcagcag ttcgttttgt tcctactgtg ttaatgatag cttgaattct tcctttgcgt
     9361 acaaaacttg ggatatcctt atcgtcatca ccaatcttac caacaggttg ggcttgcaag
     9421 ccatggctag caaagaaggc tgctgtccct tctgtcgcaa ggattccata accaatgttt
     9481 tggaaacgac gagccaagtt caaggcttct tctttggcat catcagcgat ggtaaagacg
     9541 acattaccaa aagttggcaa gtgtagataa gaagcttcaa aggctttata gagagctttt
     9601 tccaaagtag catcagaacc cataacttca cctgttgact tcatttcagg accgagcaag
     9661 ctgtctacct tagctagttt ggtaaaggag aagacaggtg ccttgatatg aacacgggtg
     9721 ctttcagggt aaagtccatt ttggtagcca agttctgata aactttgacc aagaatgagc
     9781 ttggtcgcta cttgagccat aggaatattg gttaccttag ataggaatgg aacagtacgg
     9841 ctggcacgtg gattgacctc aataacgtag actttttcat ccttgataac aaactggatg
     9901 ttcatcattc caaggcagtg aagaccgatt gctaagcgtt tggtgtagtc tgcgatggtc
     9961 tcctgaacct tttgcgacaa ggtttgtggt gggtaaacag ccattgagtc acctgagtgg
    10021 acaccagcac gttcgatatg ctccatgata ccaggaatga gtacatcttt accatctgaa
    10081 atggcatcaa cttcgcactc ttgcccaacg atataagagt cgacaagaac tgggtgatct
    10141 ggactagcct taacagcagt tcgcatgtaa gaacgaaggt cttcttcgtt ttcaacgatt
    10201 tccatggcac gtccaccaag tacataagat gggcggacaa gaactgggaa gccaatctta
    10261 cgagctgcaa gagctgcttc ttcttcattg gtagccgttt gtcctggtgg ctgtggaata
    10321 tccaattctt tgagagcttg ctcgaagagg tcacggtctt cggcacggtc taggtcagca
    10381 acctgtgtac caaggatggt cacacctgct tttgccaatg gctccgcaag gttgatggct
    10441 gtttgaccac cgaactgaac gataactccc tttggttgtt ccaagtcaat gacgttcata
    10501 acatcttcga atgtcaatgg ctcaaagtaa agcttatctg atacagagaa gtctgttgaa
    10561 acggtctctg ggtttgagtt catgatgata gcttcataac cagctgcctg gatagcctta
    10621 acagagtgaa cggttgcgta gtcaaactca accccttgac cgatacggat tggacctgaa
    10681 cctaggacaa gtacagattc tttatcagat ctgatagatt cattttccca accataggtt
    10741 gaatagaaat atggcgtttc ggagtcgaac tctgccgcac aagtgtctac catcttataa
    10801 actggaacaa tcttgttttc caagcgaagt tggcgaactt tatcatcagt cgttccccag
    10861 agttcagcaa tcttacggtc tgaaaaacca ttaagtttgg ctgttttcaa aacttctaga
    10921 tcttgtggat gagcacccaa ttcttgctca atttcaaaga tatgcaagag tttatcaaga
    10981 tagaagatat caatttttgt aagctctgca atttcttcag gtgtgtagcc acgacgaatt
    11041 gcttctgata cgtagaagag acggtcatct tgggctttga caaccttttc aatcaaggca
    11101 tcatcagaaa ctgctgcaag ttcaggtatt tcattgtggt gcaccccaat ttcaagggag
    11161 cggcaggcct tgagaagaga ttcctcgatg ttacgaccga ttgccatgac ttctccagtc
    11221 gccttcattt gtgtaccgag acggcgttca cccttttcaa acttgtcaaa tgggaaacgt
    11281 ggaatcttag caactacgta gtcaagggct ggttcaaaca tggcataggt tgaacctgta
    11341 actgggttta taacctcatc caaggtcaaa cctactgcaa tcttggcagc caacttagca
    11401 atcggatatc ctgtcgcttt agaagcaagg gctgacgaac gtgatacacg agggtttact
    11461 tcgataacat aatacttgaa gctgttagga tcaagagcta gctgaacatt acatccacct
    11521 tcaatcttga gggcacgaat aatgctcaag ctcgcatcac gaagcatttg gttttcatag
    11581 tctgacatgg tttgcgcagg ggcaaataca atggaatccc ctgtgtgaat cccaactggg
    11641 tcaaagtttt ccatgttaca aacaaccaag gcattgtcag ctgagtcacg catcacttcg
    11701 tattcaattt ccttgaaacc ggcaatcgaa cgctcaatca aacattgggt aacaggtgac
    11761 aatttcaaac cattttcagt gatttcacgc aattctttct cgttggcaca cataccacca
    11821 ccagtaccac caagggtaaa ggctggacga acgatgactg ggtagccaat tgtcgctgca
    11881 aaggcaactg cttcttctac tgtgttaaca atttcagatt ctggaatggg ttgttcaagc
    11941 tcttccatca attgtttaaa gaggtcacgg tcctccgctt ggtcaatggc agataatttg
    12001 gtacccagaa gttcaacgcc aagctcgtct aggataccat ttttagataa ttccatggcc
    12061 atgttgagac ctgtctgacc accgagtgtt ggtagcaagg catctggacg ttccttacga
    12121 agaatacgtg tcacaaactc aagtgtaatc ggttcaatgt aaaccttgtc agcaatttcc
    12181 ttgtccgtca tgatggttgc aggatttgag ttaaccaaaa caacctcata accttcctct
    12241 ttcaacgaca agcaagcctg agtcccagcg tagtcaaact cagcagcctg gccaataata
    12301 atcggaccag aaccaatcac cataattttt tgaatatcag tacgtttagg catatataag
    12361 atattaaggg cgtcaagcgg acaaagctaa aataggagtt atgacgaaga actgtcagtt
    12421 ctaggaataa ctatcttttt agcaccgtcc gtagcccgta ttcagttcag caaatacgga
    12481 gcacccttct cctttctatt cgtcgcctct cagggcgaca ttaaataaga tacaaaggac
    12541 gaatagaaag cgattgaatt ttagaaaatc aaggaaggat tgacaatcca agttgatttc
    12601 tctacattct gagctttccg tccgtgttca gttacataaa ttctccgacg agcttttact
    12661 cgttcttagt ttgattgttt aaaaacttcc atcatctcga taaactcgtc aaataggtag
    12721 ctagcgtcgt gtggcccagg agctgcatct gggtggtatt gaacagagaa agcaggttgg
    12781 tatctgtggc gcacaccttc cactgacttg tcattgattt cttcgtgggt aataatcaag
    12841 tgctctggca aatcctcgcg gctgactgca taaccatggt tctggctggt gaagtctact
    12901 cgtcctgttg cgatttcacg taccgcatgg ttgaatccac ggtggccaaa cttcatctta
    12961 taggtcttag ccccgtttgc cattgcaaag agttggtgtc ccatacaaat accaaagatt
    13021 ggaatttttc cttgtacacc gcgaatcatg tcgagtgctt gtggaacgtc ttctgggtta
    13081 cctggaccat ttgacaacat aaccccatca ggattgagat ggagaatttc ttcagccgtt
    13141 gtcgaataag gaacaactgt cacgttacag ttgcgtttag aaagttcacg taggattgag
    13201 tgcttgagac caaagtccac tagcaccacg ctcaaaccaa ctcctggagc tggataagac
    13261 gttttagtag aaacctgttt gatattgtct gtcggtaaaa ctgttgcttg gagctggtcc
    13321 gtcacatggt ccatactgtc cccaacatgg gtcaaggttg cacgcatagt accatgctta
    13381 cggataatct tggtaagagc acgcgtatca attcctgaaa tccctggaat ttttttggct
    13441 ttcaaaaatt catccaaggt catttggttg cgccagttgc tagctctacg cgcttcttca
    13501 aaaacaacga ctcccttaca agttggaata atggattcat aatcatcacg attaatacca
    13561 taatttccta ccaaaggata agtaaaggtc aagatttgtc cattataaga ctggtctgta
    13621 atggattctt ggtagccggt catccctgta ttaaagacga tttcgcctgt tacatcaata
    13681 tctgctccga aggccttgcc ttcaaaaact gtgccatctt ctaatactag aattcttttt
    13741 gtcatatttt cacctctcgt ggacgctcac tggcgtcttt taacgtcttg tgttttagtt
    13801 ggcgtttcta ctcgctagta cggattctaa gattgccatt cgaacaaaga caccattggt
    13861 catttgttgg acaatccgtg attttggtgc ttcaaccaag tggtctgcta tttctacatc
    13921 acgattgatt ggagctgggt gcatgaggat tgctgtttct ttcaaacgat cgtaacgttc
    13981 ttgagtcaag ccatgttggg catggtagtc ttcttttgaa aatacagctc cactatcatg
    14041 gcgttcgtgt tgcacacgga gaaacatcat gacatcaacc tgatcaatga tttcatcaat
    14101 ggttacaaac tgtccatagt ctgcaaactc ttgacttctc cattcctcag gtccagcgaa
    14161 aaagagttca gctcccaagc gtttcaaaat ctgcatattg gatttggcaa cgcgtgagtg
    14221 atccaagtca cctgcaatag caactttaag accctcaaag tggccaaatt cctcataaat
    14281 ggtcatcaaa tcaagcaagc tctggctagg gtgttggccc gaaccatctc caccattgat
    14341 gatggaagtc gtaatcgttg gactagcaat caattctcta tagtagtcga cctctggatg
    14401 gcgaatcaca cagacatcca ctcctaaagc agacagagtc aaaatggtgt cataaagtgt
    14461 ctcaccctta ttaaccgaac tagtcttcac atcaaagtca agtcgttcca atccaagttt
    14521 aatctctgcg acttcaaagg acttatgtgt ccgtgtagaa tcctcaaaga agagattgga
    14581 aacaatcgga tggtcttcat agggaagctg ggctccattt ttaaactcaa ttcctcgctt
    14641 gatcaatttc attacttgat cgacagtgag gtcttccatg gacaccacat ggttcaatgc
    14701 ttgttgattt tctgacatgg ctactccttt aactttctaa gcttcttcag taatcagaac
    14761 tctgtcttgg tcatcaagtt ctgtcatctc tacgatgatt tcttcagaac gactggttgg
    14821 gatatttttt ccaacgtaat ctggacggat tggcaattct ctatgtccac gatcgactag
    14881 aactgctaaa ctcacacgcg caggacgacc atgaccgaca atattatcaa tagcagcacg
    14941 gatggtacga cctgtataga gcacatcatc caccaagata acttcgcggt ctgtcacatc
    15001 gacagaaacc aaagaagtat cttctccact tttaacatca tcacggaaag gtttagtatc
    15061 caattccaca acaggaactg aaagattttc taactgcttc aaacgttctt ggattcggtg
    15121 ggcaataaag acaccacgag ttttaatacc agccaagacg atcttattca aatctttgtt
    15181 gcgttcgata atctcataag taatacgcgt aatcgctcgt ttgacggtca attcgtctac
    15241 aacttctttt gttttcatga caaacctcca aaaagaaaag tctccttaaa caaggagact
    15301 tgaaatttat agccaagcga gccctactgc acacagtata gacttcaccc ttctacttta
    15361 tcgcgctcct tgcctgcctc acgggacagg tttaaaggaa tatttagtta tcatttacta
    15421 tagcacaaag catgcttaaa atcaagcaaa aagtttcaat gtagcatctt acaaattgct
    15481 aaaatcatat aattgtgggt actggtcaca ctctggattt tttggatggc aaatggctct
    15541 tccaaaataa atcatggcct gatgggcagc taaccactgc tcaggcggca agatatccat
    15601 gacccgcttt tccacctcaa gtggcgtcgc tgattttttg acaatatcgt ggtgtttgca
    15661 aatacgctcc acatgagtat ccactgcaaa ggctggaatc ccaaatccta cactcatgac
    15721 aacattggct gtcttgcgac caacacctgc caaactctcc aattcttcac gtgtctgagg
    15781 gacttgacca tcaaaatcgt ctagtaactg ttgggcacat tttttaagga atttagcttt
    15841 attccgatac aatcccaagc gagaaatatg tgaagcaatc tcactctctg tcgctacaga
    15901 catagcttgg ggtgttggaa aggcaacaaa gagacctggt gtggccttat ttaccgctgc
    15961 atctgtcgtc tgggctgata acatgaccgc aaccaggagt tcaaaatgat tggtaaaatc
    16021 aagactaggc ttggcatctg ggaagagggt aatgatttct tctagcacct ttcgtgctcg
    16081 tttttttgac aagaccatta ttcatctccg tcaaatagtc cttgtaagcc agcaaaagga
    16141 ctgttttctt ctttctttac tgctttttga gcttggtatt cttcctctgt catgatttgc
    16201 cagtcatttc ctgagataaa tccttgacca gcttcttctt cagccgtcaa gaccttgata
    16261 ggaatgttta gcaggatatt gtctgataca ctctcagcaa ggtcaagctc cccattttcg
    16321 atgggcaaga ccaagtcatc atctaaaact tcttgatcta gctggttagt tgcgccttcc
    16381 atgaaaactt ccgtgactgg ataagattca actaactcaa ctggctccat actgcgactc
    16441 gaagcaagaa caatggtata agatagttga taatctaaga aatacatacg gtcttcatat
    16501 tgtactttcc caactgcaag gatatctttt acatctaaaa tttcttgatt acgtgcacgc
    16561 aggtcatcaa ctaaatctaa cgtttgttca aagttcaaac cttcagactg cttacgaatt
    16621 tcttgaatat ttaatttcat acttcctcca taaagattta ctctcttgat tataccatga
    16681 aaaggctaca aatcagcaca ccaaactttg taattaaaat tcaaaatttt aacatattta
    16741 ctattatagt tttatttttt agtgctatac tatagggaaa gagtacatca gatcaaggag
    16801 gatgctcaca tggaagacaa gaaactcatt caactcctat ccaagttaaa taaaagctac
    16861 caaaactgta aacagggtac ggcagatgat attcgactac aagagctgct aaacactact
    16921 atgcaagagc tcaaaaaaac ggaacagttg aacaacagta tcttaattga tcttgagaaa
    16981 ttttaccaac ctaccagtct tctgattgga ctgggtagcc taaaactaaa cgatcaagca
    17041 cgcactgctt ggcgaaacta tgataaattc cattacgagc atgtcaaaca cgtactaagt
    17101 ctctatggac ctgtttttga attttagagc atagaatttc cagttttctg ttgacaaaat
    17161 ttccttaaag gtataatata aagatactaa tactcggagg taagggagac atgaacaact
    17221 aagtctatca aataaagaac ctttatttag tagatcttgt ttttgtctct ttttgtgtgc
    17281 tcttttatgc tctttttctg gcatgttaat agagtttttt tgacatagac tttgggctct
    17341 actaggtaaa gtagagcttt ttgttatgca ctatgaacat tctagaaagg gaaatcatat
    17401 gataaaaatc aatcatctaa ccatcacaca aaacaaagat ttacgagatc ttgtatctga
    17461 cctaaccatg accatccaag acggggaaaa ggttgctatt attggtgaag aaggaaatgg
    17521 caaatcaacc ttacttaaaa ttttaatggg ggaagctttg tctgatttca ctatcaaggg
    17581 aaacatccaa tctgactatc agtcactggc ctacattcct caaaaacttc ccgaggagct
    17641 gaaaaagaaa actttacacg actacttctt tttagattct attgatttag actacagtat
    17701 cctctatcgt ttggcggagg aattgcattt tgatagcaat cgtttcgcaa gtgaccaaga
    17761 gattggcaat ctatcagggg gagaagcttt gaaaattcag cttatccatg agttagccaa
    17821 accctttgag attctatttt tagatgaacc ttcaaatgac ctagaccttg agacagttga
    17881 ttggctaaaa ggccagattc aaaagaccag gcaaaccgtt attttcattt cccatgatga
    17941 agactttctt tctgaaacgg cagacactat tgttcacttg cgactggtca aacaccgtaa
    18001 agaagcggaa acgctagtag agcatttaga ctatgatagc tatagtgagc agagaaaggc
    18061 taattttgcc aaacaaagtc agcaagctgc taacaaccaa agagcctacg ataaaaccat
    18121 ggaaaaacat cggagagtta agcaaaatgt agaaactgcg cttcgagcta ccaaagatag
    18181 tactgccggt cgcctattgt ctaaaaagat gaaaactgtc ctctcacaag aaaaacgcta
    18241 cgaaaaggca gctcagtcca tgactcaaaa accacttgaa gaggaacaaa tccaactttt
    18301 cttttcagac atccaaccat taccagcttc taaagtctta gtccaactgg aaaaagaaaa
    18361 tttgtccatt gacgaccgag ttttggttca aaaactacaa ctaactgtcc gtgggcaaga
    18421 aaaaatcggt attatcgggc caaatggtgt tgggaaatca actctgttag ccaaattaaa
    18481 gcaacttctg aatgataaaa gagagatttc ccttggtttt atgccacaag attaccacaa
    18541 aaaactacaa ttggatttat caccaatagc ttatatcagc aaaactgggg aaaaagagga
    18601 acttcagaaa atccactctc acctagccag tctcaatttc agttatccag aaatgcagca
    18661 tcaaattcgc tccttatctg gcggacaaca gggaaaactc ctgcttttgg atctagtcct
    18721 gcgcaaacca aactttctcc tgctggatga acccacacga aacttttctc ccacttctca
    18781 accccaaatc agaaaactct ttgcaaccta tccaggcggt ctcatcactg tttcgcatga
    18841 ccgtcgtttc ttaaaagaag tctgctcgat catctatcgc atgacagaac acggtttgaa
    18901 gctagttaat ttagaagatt tataaatttg caacatagca aaaatccaga gacgacctct
    18961 ggattctttt acatctgttt taaacgttca atccgttctg agataggtgg gtgggtataa
    19021 aagagttttt ggaacccccc acctttcttg ggatcattga tataaagagc actgctagca
    19081 tcatcgacgt ggcgactcat cggtttgcta ttgtccaact tatctagggc attaatcatt
    19141 ccctggggat tgcgagtcag ctcaacacta gatgcatctg ccagaaattc cctctgacga
    19201 gaaatagcga gctgaaccaa ggttgcagcg agaggtgcca gtacaatagc tagtagggaa
    19261 accactagca taatgatttc aagaccattt ccatctcggt catcatcact tcgtctgcga
    19321 cctgctccac cccaccacat catacgacct gccataccag aaagcatggt gatagcacta
    19381 gcaagggcaa ctgcaatagt cgaaatacgg atatcataat tacgaatatg actgacttca
    19441 tgtcccataa cagcttctag ttcttcacga ttcatgatag ctagtagacc tgaagtcgca
    19501 gcaacagccg cattttgagg attagaacct gtcgcaaagg catttaaggc tggatcatca
    19561 atgatgaaaa cacggggcat aggaatctga gcgaccagag ccatatcttc cactacatgg
    19621 tagaggtctg gtgccgtttg ctcatccacc tcacgcgctc cattcatgga catgacaatc
    19681 tctgtcgatt gaaaaatcat agacaaagcg tagataaagc cgataatcag tgcgataacc
    19741 aaaccaccaa gtccagatct tataaagaga taaccaaccg cataaccaac aagagctaag
    19801 agtaggaaaa ataccagcaa caaaatccag gtttttcgtt tattgcttgc aatttgatca
    19861 aacaacatct tagtcaccta aaccgctaaa atcaacttta ggaaccgact tttcctcttc
    19921 aggtgtttga aggaaatctg ccgctttaaa tccaaacatt ccagcgataa tattgctcgg
    19981 gaaagtttct aattttacat tgtagttgct gacaacactg ttatagagtt gacgagagta
    20041 agaaatttta ttttctgtgt ttgtcaactc ctcttgcaat ttaacaaagt tagcactagc
    20101 tttcaaatct ggatagcttt ctgcaactgc aaaaatacct gaaacctgac gagtgagggc
    20161 atcactggct ttcatagctt ctgctggtga agtcgctgcc gccacttggt tacgtagttc
    20221 tgccaccttt tcaagggtag aaccttcata tttggcataa ccttttacag tctcaatcaa
    20281 gttcggcaag aggtcatttc gacgtttcaa ctgaacatca atctgactcc aagcctcctt
    20341 ggtttgcata cgatttttaa ccaaaccgtt atagctaaca atcacaaaaa taacaataag
    20401 agcgataact ccaagaataa tccaagtcat aatataagtc ctttctgctt ttagattagt
    20461 accagtatat caaattttct atgattgtgg taaaataaga tgatactaaa gaaggaaata
    20521 actatgaaac caaaaacatt ttacaacttg cttgccgagc agaatcttcc actttcggac
    20581 cagcaaaaag aacaatttga acgttatttt gagctcttgg tcgagtggaa tgagaagatt
    20641 aatttgacgg cgattacgga caaggaagaa gtttatctca aacattttta cgattcgatt
    20701 gcacccattc ttcaaggttt gattcccaat gaaactatca aacttcttga tatcggggct
    20761 ggggcaggat ttcctagtct accaatgaaa attctctatc cggagttaga tgtgaccatt
    20821 attgattcac tcaataagcg catcaacttc ctacaactct tggctcaaga actggatttg
    20881 aacggagttc atttctacca cggacgtgcc gaagattttg cccaagacaa gaacttccgt
    20941 gctcaatatg attttgtaac agctcgtgcg gttgcccgta tgcaggtcct atctgaattg
    21001 accattccct accttaaggt tggtggaaaa ctattggcac tcaaggccag caatgcgcct
    21061 gaggaattat tagaagctaa gaatgccctc aatctccttt ttagtaaggt cgaagacaat
    21121 ctcagctacg ccctaccgaa tagagatccg cgctatatca cagtggtaga aaagaaaaaa
    21181 gaaacaccaa ataaatatcc acgtaaggct ggtatgccaa ataaacgccc actttaaatt
    21241 ttttagtaaa caaatgttta caaaatcagc ctcgctcttt tatttctagg ctcgggaaaa
    21301 aatgatttac aaaatcattt ttttctgcta tactatccta agcaaaggtt tttaatgtca
    21361 tcccgtgagg tgacgaagac gcagaaatat ttaaaactct ttaaaatcta aattttaaag
    21421 aagtcttact ctgagggcct attgctgtaa aataatgggc tcttttttga tgcccaaaag
    21481 tgaggtttat atgaaacaag aatcaactgt tgatttgtta ctagacgttg accaacgtcc
    21541 ttcggctgga aaaggaattc tccttagttt ccaacacgtt ttcgccatgt ttggtgcgac
    21601 catcttggta ccattgattt tgggaatgcc tgtatctgtt gccctttttg cttcaggtgt
    21661 tggaacactc atctacatgc ttgctactgg ttttaaagtt ccagtttatc taggttcttc
    21721 attcgccttt atcacagcta tgtcactggc tatgaaagaa atgggggggg atgtatctgc
    21781 tgctcaaaca ggggttatct tgactggttt ggtctatgtc cttgttgcta ccagcatccg
    21841 atttgtagga acaaaatgga ttgataaact cttgccacca atcattatcg gtcctatgat
    21901 catcgttatc ggtcttggac ttgcaggttc agctgttacc aatgcaggtc ttgtagcaga
    21961 cggaaattgg aaaaatgctc tggtagccgt tgttactttc ctaattgctg cctttatcaa
    22021 tacaaaagga aaaggcttcc tacgaatcat tccattcctc tttgccatta tcggtggtta
    22081 cctcttcgca ctaactcttg gtttggttga ctttacgcct gtcctagaag ctaactggtt
    22141 tgaaattcct ggtttctact tgccatttag cacaggtggt gcctttaaag agtacaatct
    22201 ttactttggt ccagaagcca tcgctatctt gccaatcgct atcgtaacaa tttctgaaca
    22261 tatcggagac catactgttt tgggtcaaat ctgtggtcgt caattcttaa aagaaccagg
    22321 tcttcaccgt actcttcttg gtgacggtat cgcaacttct gtttctgcct tccttggtgg
    22381 accagccaat acaacttacg gagaaaatac aggggttatc ggtatgactc gtatcgcttc
    22441 tgtctcagtt atccgtaacg ctgccttcat cgcgattgcc ctcagcttcc ttggtaaatt
    22501 cactgccttg atttcaacta ttccaaacgc tgtacttggt ggtatgtcaa tccttctcta
    22561 tggggttatc gccagcaatg gtttgaaagt cttgattaaa gaacgtgttg atttcgctca
    22621 aatgcgaaac ctcatcatcg caagtgctat gttggttctt ggacttggag gagctatcct
    22681 taaacttggt ccagttacac tttcaggtac tgccctttca gccatgacag gaatcatctt
    22741 gaacttgatc ttgccatacg aaaataaaga ctaagagtct aaatacacct aatccactca
    22801 gacagctgag tggatttttc gtataccata ataaaagtgt cttaacaaaa ttattaaaat
    22861 caaaaaacgt ataatatcag atattctaaa accttgatac tgtacgtttt atcatagaaa
    22921 tttttacttt attttctcat caaatgagat ttgcatcaat ctcttgtctt acttgcgttt
    22981 cttcttcgct ttcttcattt tgttagccat acgtttcatg gactgtttca tggcaaattc
    23041 accaatttta cctttcaaac cgccaccaaa catctggctc atatctggca ttcctgctcc
    23101 tccgagagct gataagtcag gcataccgcc ttgtcccatc attccttcaa gggcagacat
    23161 atccattcct cccatatttg gcatattttt aggaaggtta tttggattaa tccccatttg
    23221 cttcatcatt ttattcatat ccccagacat aacaccctgc atgagctgtt tagcctggtt
    23281 aaagtccttg atgaatttat tgacttcgac gaatgtattt ccagaaccag cagcaatacg
    23341 acggcgacgg cttggattta acaaatctgg gttttcacgc tcttcaggtg tcatcgaaga
    23401 cacaatggca cgtttacgag caatctggcg ttcatccacc ttcatgtttt gaagggctgg
    23461 attgttggcc atacctggaa tcatcttgag caagtcttcc atcggcccca tattttgcac
    23521 ctgatctaat tgatcgatga aatcattaaa atcaaaggtg ttttcgcgca tcttctcagc
    23581 catttcaagg gctttttgtt catcgtattc ctgagaagct ttctcaatca aagtgagcat
    23641 atcccccatg ccaaggatac ggctagacat acggtctggg tggaaggttt cgatatctgt
    23701 aattttttca cctgtaccag tgaacttgat tggttttcca gtgatgtgac gaacagacag
    23761 agcagcacca ccacgagtat caccatcaat cttggtaagg atgaccccag tcacttccaa
    23821 ctgagcatta aactcacgcg caacattggc tgcttcctga ccaatcatag catcaacgac
    23881 aagcaagatt tcatttggtt gagccaatac tttcacatca cgaagctcat tcatgaggag
    23941 ctcatcaatc tgcaaacgac ccgcagtatc aatcaagaca tagtcgttat gattagtttg
    24001 ggcttgctcc aaaccttgac gtacaatctc aacagctggt acttctgttc caagtgcaaa
    24061 gacaggcaca tcaatctgtt gtcccaaggt cttaagctgg tcaatggcag ctggacgata
    24121 aatatccgcc gcaatcatca aaggacgagc attttcttct ttcttgagtt tgttggccaa
    24181 tttaccagca aaggttgttt taccagcccc ttgtaaacca accatcatga tgatggttgg
    24241 aatcttaggt gacttgataa tttctgccgt atcagaacct aaaacggctg tcagttcctc
    24301 atcaacgatt ttaataatct gttgcgcagg attaagcgta tcaatgacct catgcccgac
    24361 tgcacgctca cgaactttct tgataaagtc ctttacaaca ggcaaggcaa cgtcggcctc
    24421 gagcaaggcc aagcgaattt ctttggttgc ctcttggaca tcagattcag agatttttcc
    24481 ttttttacgt agatttttaa agacgttctg caaacgttct gttaaacttt caaatgccat
    24541 ttttcttcct cttattctct attatcaatg cttgttaaaa tttctatctg ctcctgcaga
    24601 aagtcatcct tgggatagcg ctccaaaatc tgatcaaaaa tctgactgcg gacaatatag
    24661 tccgagtaca tgtgcaattt catctcataa tcttccagaa tcttttctgt tcgcttgata
    24721 ttgtcataga cagcctgacg actgacaccg aactcctcgg caatttcagc aaggctgtaa
    24781 tcatcagcgt agtagagctc gatataattc atttgcttat ctgtcaaaag cgccgcataa
    24841 aattcaaaga gcgcattcat acgattggtt ttttcgattt ccataacttt tattatacca
    24901 aaaattagcc taatctacca cactaggaag ccgatccaag aagatagata gctaaatttg
    24961 aaaaagacat gagcctagcc ccaagtaatt tccaattgat agctggcaaa gggatgtccc
    25021 tcttgatttt gtagttgata atctagttca atcttttgcc catccacttg ataacgattc
    25081 gtttggataa taaactcctg catacccata ggtgtgggaa tataggctaa actatcacta
    25141 tcctttagaa agcgcataat ggtcttggga ttggaaaatc gactcatcac aagttcttga
    25201 ccatgaaatt taatcactac tttttccttt tcctcattat agaaaagcag gtagctataa
    25261 tctccttttt catgcacttc cacatcataa agctggtcaa tcacttccaa ctgctcatca
    25321 aactgaattg tatttcgcat ccgaatcttc acatcaggcc ctctttcttg tctcttgtcc
    25381 tactatttta ccaaaaagag caggattttg ctataatggt catatgaacg aaaaagtatt
    25441 ccgtgaccct gttcacaact acatccatgt caataatcaa atcatctatg acttgattaa
    25501 tacaaaagaa tttcaacgtt tgcgccggat caaacaactg ggaacttcca gttatacctt
    25561 ccacggtgga gagcatagtc gcttctctca ctgtctagga gtctatgaaa ttgcacgacg
    25621 catcacagag attttcgaag aaaaatatcc tgaggaatgg aatcctgccg agtctctctt
    25681 gaccatgacc gctgctctcc tacacgacct tgggcatggt gcctactccc atacttttga
    25741 aaatctcttt gatacagacc atgaagccat tactcaggag attattcaaa atcctgagac
    25801 agagattcac caagtcctgc tacaagtggc acctgatttc ccagaaaagg tggccagtgt
    25861 cattgaccat acctatccta ataagcaggt cgtgcagctc atttctagcc agattgatgc
    25921 ggaccgcatg gactatctct tgcgtgactc ctattttaca ggagcatcct atggggaatt
    25981 tgacctgact cgaatcctcc gagtcattcg tcctatcgaa aatggtatcg cctttcagcg
    26041 caatggcatg cacgccatcg aagactacgt cctcagtcgc taccagatgt acatgcaggt
    26101 ttatttccac cccgcaacac gcgccatgga agttctccta cagaatcttc tcaaacgcgc
    26161 caaggaactc tatcctgagg acaaggattt ctttgcccga acttctccac acctcctgcc
    26221 tttcttcgaa aaaaatgtga ccttgactga ctatctggct ctggatgatg gcgtgatgaa
    26281 tacctacttc cagctttgga tgaccagtcc tgacaagatt cttgcagatt tatcgcatcg
    26341 ctttgtcaac cgcaaggtct ttaaatccat taccttttca caagaggacc aagatcaact
    26401 tactagcatg agaaaattgg ttgaggatat cggctttgat cccgactact acactgccat
    26461 tcataagaac tttgacctcc cttatgatat ctatcgtccc gaatctgaaa acccacggac
    26521 acagattgag attttacaaa aaaatggaga actggccgaa ctctctagcc tgtctcctat
    26581 cgtccaatcc cttgctggca gtcgccacgg agataatcgc ttttattttc caaaagaaat
    26641 gttggaccaa aacagcatct ttgcaagcat tacccagcaa tttttacact tgattgagaa
    26701 cgatcatttt accccaaata aaaactagaa gaggaatttt atgagtatta aactaattgc
    26761 cgtcgatatt gacggaaccc tagtcaacag ccaaaaggaa atcactcctg aagtcttttc
    26821 tgccatccaa gatgccaaag aagctggtgt caaagtcgtg attgcaactg gccgccccat
    26881 cgcaggtgtt gccaaacttc tggacgactt gcagttgaga gaccaaggtg actatgtggt
    26941 gaccttcaat ggtgcccttg tccaagagac tgatactggc catgagatta tcagcgaatc
    27001 cttgacctat gaggattatc tggatatgga atttctcagt cgcaagcttg gtgttcacat
    27061 gcatgctatt actaaggacg gtatctatac cgccaatcgc aatatcggaa catacactgt
    27121 gcacgaatca accctcgtca gcatgcctat cttctaccgc actcctgaag aaatggctgg
    27181 caaggaaatt gtcaagtgta tgttcatcga tgaaccagaa atcctcgatg ctgcgattga
    27241 aaaaatacca gccgaatttt acgagcacta ctctatcaac aaatctgctc ctttctacct
    27301 cgaactcctt aaaaagaatg tagacaaggg ttcagctatt actcacttag ctgaaaaact
    27361 aggattaacc aaagatgaaa ccatggctat cggagacgaa gaaaatgacc gtgccatgct
    27421 ggaagtcgtt ggcaaccctg tagtcatgga aaacggaaat ccagaaatca aaaaaatcgc
    27481 caaatacatc accaaaacaa atgacgaatc cggcgttgcc catgctattc gtacattggt
    27541 actgtaaaag gaaagaatag ataaaaaccg ctcagctgag cggtttttga tgtctaatta
    27601 ctgccccctg caggaatcga acctgcaact actccttagg agggagttgt tatatccatt
    27661 gaactaaggg agctagataa aaactctgct gaaaagcaga gttttttagt cgaattaacg
    27721 acggatttct ttgatacgag ctgctttacc ttgaagagca cgcaagtagt acaatttcgc
    27781 acgacgtact ttaccgtaac gaacaacttc gattttttca acacgtggag tgtggattgg
    27841 gaagatacgc tcaacaccta caccgttaga gattttacga actgtgtagt tttctgagat
    27901 tccagcacct ttacgtgcga taacaacacc ttcaaaaatc tggatacgtt cacggttacc
    27961 ttcgacaact ttcgcgtgta cacgaacagt gtcaccagga cggaatgatg ggatatctgt
    28021 acgaagttga ccttcagtca agctttggat taatggattc attttattct cctatctttg
    28081 tcaatcttga ggaatcttcc tcagcggata aactgtattt ttgtgcgtcc attacacaca
    28141 agatatagtt taccaaattt ctaaaaaaaa gtaaagaaat ttatagcaaa attcctaaaa
    28201 aaatcgcaac caaaccacct atgtaagtca aagtcaggta agaataaaag accttcttat
    28261 cacttagcag tctttgaagt tcgtcattca aggtcgaaaa agttgttaaa ccgccacaaa
    28321 atcctgttgc tagaatagca tatacttcct tagactctac atgattgtag aatactccaa
    28381 ttaaaaaaca acctaaaaga ttagctatga gcgttccgag tggcaattta gaagcttgat
    28441 tatagcgaga aaagaaatac cgtacgagtg ctccgaaacc acaagcaatt gcaagataga
    28501 cgattaccat ttcttcctcc ctagaaaata agctaagagt aggcctccac cgatgctcaa
    28561 aagcaaatac aggactaaac taagataacg ccctgtatca agcagcttca cagtatcaag
    28621 cattaggctg gaaaaagttg ttaaacctcc gcaaaaaccc gtccccagtg ctaaaatcaa
    28681 gcccttacta gtccccttat agaccagata gcccttgaca agaaaaatca agcagaaaat
    28741 tcccagatag ttgacaaaga gagtgcccca aggaaagtct ggactggctg gtaaccaggt
    28801 ggaaactaga tatcggacaa gtccgcccaa catagcagct agaaaaattc ctagcggata
    28861 aaattgttct tttttcattt gatattttga tcctgataat cacgcgaacg tttgagtatg
    28921 tccgaaaaag tcgcgacaat agtctcctga tagcgcttgt cctctacacg actcctaacc
    28981 ttttcaaaaa taacttcttc tctcttagta tctaaaatcg gtttacctga agctttctta
    29041 taagcaacca ccccctcaac taaatgcatt cgttcttcta acagtttgac aatttggtcg
    29101 tcgatttgat cgatttcttg acgaataata tctaaatcca tacagtctcc tcctttattt
    29161 gaattattgt atcaaaaagc catcaattag gctagtaaaa tcccaactct cgataagaaa
    29221 aatgcactga ttgattacat cagcgcactt ttatgtttat cctactttag cagccaattc
    29281 ttctgcgaat tgttccaagc gttcaatatc ttcttcctcg gcagaaagat caactttaac
    29341 acactctgaa cctttttctg ctcctgttga cacaaagaca cggtcaaagt catcaacagc
    29401 cttacagaat tcatcgtaga aggtatctcc tgagccgacc actccgtaga ttttgccatt
    29461 caagttgaga tctgctaggt cttcgtagaa gtccatcatc tcatctggca attcaccatc
    29521 accataagta taggtcgcaa cgatagcgat gtctgcttcc aagaagtctg aagcgtcaac
    29581 agttgtacat tcatcaacat caacatccaa gcccaagtca cgtaatttgt ctgctacaat
    29641 atctgcaatt tcttcggtat taccggtcat actggcaaat acaatttttg ctaatgccat
    29701 atcgtcctcc tcaatttatc tttctccatt atatcacatc tttttcattt taaaaataaa
    29761 aattcttgtg ctacaatgaa atgagaaaga attgaggtta tttatggaga tttgccaaca
    29821 aattttagaa aaaattaaag aatacgacac cattatcatt catcgtcata tgaaaccaga
    29881 ccctgatgcc ttgggaagtc aggtgggatt gaaagccttg ctggaacatc atttcccaga
    29941 aaaaaccatc aaagccgtcg gttttgatga accaactctt acttggatgg ctgagatgga
    30001 tcttgttgaa gatagagcct accaaggcgc acttgtcatc gtctgtgata cagctaatac
    30061 tgctcgtatc gatgataagc gctatagtca aggtgatttt ctcattaaga ttgaccacca
    30121 tccaaatgat gatgtatacg gtgacctgtc ttgggtcgat actagttcaa gtagcgctag
    30181 cgagatgatt accctatttg cccaaacaac ccaactagcc ttggcagatc gcgatgctga
    30241 gttgctcttt gcaggaattg tcggtgatac aggtcgcttc ctctaccctt ctaccactgc
    30301 acggactctt cgcctggctg cttatttgag agaacataac tttgactttg cggctctcac
    30361 tcgcaaaatg gacactatga gctacaaaat tgctaaactg caaggctaca tctacgacca
    30421 tctggaagtg gatgaaaatg gtgctgctcg cgttatcctg agtcagaaaa tcttgaaaca
    30481 atacaatata accgatgctg aaactgcggc cattgtaggt gcacctggac gcattgacag
    30541 agtgagtctc tggggaattt ttgtcgaaca ggctgatggc cactaccgag ttcgcttacg
    30601 cagtaaagtc catcctatca atgaaattgc caaggagcat gatggtggag gccaccctct
    30661 agcaagtggt gctaattcct atagcctaga agaaaacgaa atcatctacc aaaagttaaa
    30721 aaacttgctt aaaaactgat aaaatacttg ccaaactttt cagaatctga tagactagta
    30781 tagtaacaat ctatggctcg caaagagacc atggcagaaa ggaaatattg caaaatgaaa
    30841 aaagatatcc atccagaata tcgcccagtt gtcttcatgg acacaactac tggttaccaa
    30901 ttccttagcg gttcaacaaa acgctctaac gaaacagttg agttcgaagg cgaaacttac
    30961 ccattgatcc gtgtggaaat ttcatcagac tcacacccat tctacactgg acgtcaaaag
    31021 ttcactcaag cagatggacg cgtggatcgt ttcaacaaaa aatacggtct caaataatga
    31081 taagagaaca gttttggctg ttcttttttg tttcttgaaa tcaactgctg ttttcatgtt
    31141 ccagactcat ctgtaggttc gatttccatg ctactaggca ggaaggaaat agctgtttca
    31201 acacgtccat aatgagctat actattgtca cgaaccacac tttcattgat ggtccaagtg
    31261 gaattcattt tcttaaaagc ttctcggact ttttccaaat ctttggaggc aatggcctgc
    31321 tctaaggttt caaaacgagg acttagacgg tttaccaatt tttccttttc cgcatctagg
    31381 tcaacaggat tttgttcttt ttcaaaagct aatagagctg aggaaatttc ggtgagtttg
    31441 gcttcagtaa tatctccaga tagagctaac ttttccttaa caatcttacc aacctcagaa
    31501 tccttatttt ctactctttc gaagtctgat gccatcttcg taacgagttt ctgggtctca
    31561 gtctgaccac catttttaac cgttttggat gcatctgtga ttttcacaaa gaaaaaactc
    31621 aagctttctt gggcacctgc tggggaaaga attaaaaatg acaaagctaa aactagtaac
    31681 cagcttttag ccttccaata atttctgacc aatgtagcct cctttctcca caccaccaaa
    31741 gcaagtaaaa agtccactac ctatgtgagt gatgtattca ttcatcttat cagtagcacc
    31801 taggttagtt tgaaccttaa caaagttatc aggatccttc tggaaagaaa tgaagagcaa
    31861 tcccgtatca aactgaccag tcttttcatc aatgccatct gagtaagaat aagaacgacg
    31921 taaaagtggc ttatccactt ctttggccaa acaaacatgc gaatcatcag gtaagagact
    31981 caaatccact tcatcaaact catttttctt accaaagggg gcaccgcttt ccttgtaacg
    32041 accaaaggta ttttctcgtt cttcgagact agtgcggtcc caggtctcta aaaacatctg
    32101 aatccgacga actgccatat aagaaccatt ttccatccag tccttactat cagcccagat
    32161 aacgcggtca aagtcttgct ccttggttgg atttgctgtt ccatccttaa aaccaaagag
    32221 gttccacgga gtctccattc gatccccgat agctgcaaat ccagactgac tccaacgaag
    32281 gggcaccgca tttctcccct tacggatgag attgcgaata gcgtgaaagg caatttgctc
    32341 atcatctgca caagcatgaa tcacaatatc tccaccagta tatttttcac gtaattgctc
    32401 cttaggaaat agaggtaaat ccctgaacag tcgagggcgc ttgttttcca agttcatcct
    32461 tttcaagaaa cttgcagata caccaaaagt cagcgtcaaa cgatgaggat tgagcccaac
    32521 tgtctcacca gtatcgctcg gaggaaagag agcattctgt ccatcttttt taaccaattc
    32581 cccctcgacc aacttggcac tataatccgt ccaatccttg aatagctgga taattttatc
    32641 tctatccgtc gtatgcaggt ccaagacaac aaaatagata ttcttttgca tgggcgtact
    32701 atttggtaca tcaagcgaac cttatgaaaa ggtctactgg ttttaaagcg ctttcttttc
    32761 ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg ctttcctagg
    32821 atgttctgga cgtgg
//
LOCUS       DBERAE010000022        32232 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.22, whole genome shotgun sequence.
ACCESSION   DBERAE010000022 DBERAE010000000
VERSION     DBERAE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.22"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(228..1316)
                     /locus_tag="ACL70N_001195"
     CDS             complement(228..1316)
                     /locus_tag="ACL70N_001195"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGS0590000.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTIKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(1334..2002)
                     /locus_tag="ACL70N_001196"
     CDS             complement(1334..2002)
                     /locus_tag="ACL70N_001196"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGS0590001.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(2021..4459)
                     /locus_tag="ACL70N_001197"
     CDS             complement(2021..4459)
                     /locus_tag="ACL70N_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGS0590002.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPVTTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(4610..5908)
                     /locus_tag="ACL70N_001198"
     CDS             complement(4610..5908)
                     /locus_tag="ACL70N_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0590003.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            complement(5925..6233)
                     /locus_tag="ACL70N_001199"
     CDS             complement(5925..6233)
                     /locus_tag="ACL70N_001199"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590004.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(6279..6599)
                     /locus_tag="ACL70N_001200"
     CDS             complement(6279..6599)
                     /locus_tag="ACL70N_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0590005.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(6794..7774)
                     /locus_tag="ACL70N_001201"
     CDS             complement(6794..7774)
                     /locus_tag="ACL70N_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGS0590006.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(7787..8533)
                     /locus_tag="ACL70N_001202"
     CDS             complement(7787..8533)
                     /locus_tag="ACL70N_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0590007.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            8655..9431
                     /locus_tag="ACL70N_001203"
     CDS             8655..9431
                     /locus_tag="ACL70N_001203"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGS0590008.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            9479..9703
                     /locus_tag="ACL70N_001204"
                     /pseudo
     CDS             9479..9703
                     /locus_tag="ACL70N_001204"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10041..11042
                     /locus_tag="ACL70N_001205"
                     /pseudo
     CDS             10041..11042
                     /locus_tag="ACL70N_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            11055..12146
                     /locus_tag="ACL70N_001206"
     CDS             11055..12146
                     /locus_tag="ACL70N_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590009.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            12136..13781
                     /locus_tag="ACL70N_001207"
                     /pseudo
     CDS             12136..13781
                     /locus_tag="ACL70N_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(13884..14576)
                     /locus_tag="ACL70N_001208"
     CDS             complement(13884..14576)
                     /locus_tag="ACL70N_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0590010.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(14820..16157)
                     /locus_tag="ACL70N_001209"
     CDS             complement(14820..16157)
                     /locus_tag="ACL70N_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGS0590011.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(16167..16433)
                     /locus_tag="ACL70N_001210"
     CDS             complement(16167..16433)
                     /locus_tag="ACL70N_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGS0590012.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="ACL70N_001211"
     CDS             complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="ACL70N_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGS0590013.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(17096..18031)
                     /locus_tag="ACL70N_001212"
     CDS             complement(17096..18031)
                     /locus_tag="ACL70N_001212"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGS0590014.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="ACL70N_001213"
     CDS             complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="ACL70N_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGS0590015.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="ACL70N_001214"
     CDS             complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="ACL70N_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGS0590016.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="ACL70N_001215"
     CDS             complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="ACL70N_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGS0590017.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(18999..19217)
                     /gene="infA"
                     /locus_tag="ACL70N_001216"
     CDS             complement(18999..19217)
                     /gene="infA"
                     /locus_tag="ACL70N_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGS0590018.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(19334..19972)
                     /locus_tag="ACL70N_001217"
     CDS             complement(19334..19972)
                     /locus_tag="ACL70N_001217"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGS0590019.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(20123..21433)
                     /gene="secY"
                     /locus_tag="ACL70N_001218"
     CDS             complement(20123..21433)
                     /gene="secY"
                     /locus_tag="ACL70N_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGS0590020.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="ACL70N_001219"
     CDS             complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="ACL70N_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGS0590021.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(22031..22213)
                     /gene="rpmD"
                     /locus_tag="ACL70N_001220"
     CDS             complement(22031..22213)
                     /gene="rpmD"
                     /locus_tag="ACL70N_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGS0590022.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="ACL70N_001221"
     CDS             complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="ACL70N_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGS0590023.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="ACL70N_001222"
     CDS             complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="ACL70N_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGS0590024.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="ACL70N_001223"
     CDS             complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="ACL70N_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGS0590025.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="ACL70N_001224"
     CDS             complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="ACL70N_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGS0590026.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="ACL70N_001225"
     CDS             complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="ACL70N_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGS0590027.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="ACL70N_001226"
     CDS             complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="ACL70N_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGS0590028.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="ACL70N_001227"
     CDS             complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="ACL70N_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGS0590029.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="ACL70N_001228"
     CDS             complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="ACL70N_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGS0590030.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="ACL70N_001229"
     CDS             complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="ACL70N_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGS0590031.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(26505..26711)
                     /gene="rpmC"
                     /locus_tag="ACL70N_001230"
     CDS             complement(26505..26711)
                     /gene="rpmC"
                     /locus_tag="ACL70N_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGS0590032.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="ACL70N_001231"
     CDS             complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="ACL70N_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGS0590033.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="ACL70N_001232"
     CDS             complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="ACL70N_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGS0590034.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="ACL70N_001233"
     CDS             complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="ACL70N_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGS0590035.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="ACL70N_001234"
     CDS             complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="ACL70N_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGS0590036.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="ACL70N_001235"
     CDS             complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="ACL70N_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGS0590037.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(29396..29692)
                     /locus_tag="ACL70N_001236"
     CDS             complement(29396..29692)
                     /locus_tag="ACL70N_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGS0590038.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="ACL70N_001237"
     CDS             complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="ACL70N_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGS0590039.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKLVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="ACL70N_001238"
     CDS             complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="ACL70N_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGS0590040.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="ACL70N_001239"
     CDS             complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="ACL70N_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGS0590041.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(31757..>32232)
                     /locus_tag="ACL70N_001240"
     CDS             complement(31757..>32232)
                     /locus_tag="ACL70N_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS0590042.1"
                     /translation="NLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDIL
                     ALQAGMDVLTIEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELK
                     RRLARDTTVRNRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
BASE COUNT         9639 a         6859 c         5505 g        10229 t
ORIGIN      
        1 taattaatgt attcacaata aatagccgac aacctatgtc gctttttgat ttatgaagaa
       61 cgtatagtag actgaatctg aaatagtacg aaacaattgc taaaacactt atagaaatta
      121 attttacttt cccaatcgat ttgttctcat cttatttcaa tctgctatag aattcaatac
      181 gaggatcaat aaaagactac catttggaaa acagtagtcc ttattgttta ttttgaattt
      241 acataggcat ctacagcgat aatagcttga gcaacatctg aaggcgaaat cttaaacggc
      301 atctgatgaa ttgtctcacc ctccatagtt gcttgtttac caacttttat taaatcatca
      361 tatccaactt gatccaaatg catttctttt atagttgttg gcataccaat ttttttgtaa
      421 aactcaatat acttatcaag ttcttcttta ggtctatttt ccaataatag ttgtactaaa
      481 gttccataag ctactttttc accatgtgtt aaatgatgaa tgtcacctgt caatgcagta
      541 aaaccattat gaattgcatg cgccgcagct aatcctccac tttcaaaacc tagaccactc
      601 aataaagtat tagcttcaac aatattttct aatgctggtg tcaccacttt agcttcacaa
      661 gctgccatag cctgtaaacc atctgcaaac agcgtttctt cacatttctt cgcaattgca
      721 actccagcca atgtttgctg ttgtcccaac atagtttttc catttgcctg cataaccgca
      781 cgcgcctcaa cccaagttgc taaaccatct gcaataccag acgctaataa acgcttaggg
      841 gcttgtgaaa taacttttgt atcaaccaaa actaaatctg gatttttaga ataaaataga
      901 taatgatcaa atgcaccttc atctgtataa ataacagata aagcagatac aggtgcgtcg
      961 gtcgatgcaa ttgttggagc aataataaca ggcttttcaa tcaaatctgc aatagctttt
     1021 gcgctatcaa tcgtctttcc cccaccaaga ccgataatac tatcacaatt ttctttctca
     1081 gccaaggcaa caactcgatt gatttcattg tcagaagctt caccattaaa tagcgccaga
     1141 acaatatgga aaccatacct atgtagataa tcttcaaatc gttttccaac aatatcataa
     1201 accaactgat cgcataatag aatagggcaa tttcccaaat ccaaaattga tttggcattt
     1261 tcaaacaagg cattttcccc ctgaatatat ctagaaggac tagcaaaaat tctcatatgt
     1321 atttcctctc tatctaaatg gaacgactat tttgaataac aaaccaatcg tcagaaaaat
     1381 catcaaccgc cttttggata gatggcatgg cgaaagctga ttcaaaaaca tccgctcctg
     1441 ctgtaacagc atgcgcacct gcagctaaag cattatttac ttgtgctaca tttttaaagg
     1501 atgcagctaa aatcttacta ggagagttct gtctatcaat agcaagagct aattgacgaa
     1561 tgacagaatt tgaatcaatg ttcagatttt ccattctatt ataatatgga gctaggtaat
     1621 ccgctcctgc ttcgatagct aataatccct gaataactgt ataaatagct gttgcagtga
     1681 tatggtagcc ctcttttttt agcgccttta ttgcacgtaa tccagctgga gtaacaggta
     1741 ctttgataaa tatatcatct cctgcttgtc ttcgaatttt atgagcatcc tttaagatgc
     1801 cttcaaaatc ttgagaaatc acctgaacat gaatagaggg tgtagagcca atcaattctc
     1861 ttacatcttt gattcgttca aaaaaattaa tagaaccctc tctttttgca atagtgggat
     1921 ttgaagttac cccagctagc ggcaaaattt cagaccactt tttaatctca tctaaattta
     1981 atgtgtcaag cataaattcc ataaaaagaa cctctttatt ttacaaagta tgctcagtac
     2041 gtcctataat gtcatcttgg gttgccttag aaagaacatt gaagaatgca gagtatcctg
     2101 caacacgaac aattaagtct ctgtgttttt caggatgttt ctgagcgtca atcagcgtct
     2161 ctctggaaac aacattgtat tgaatatggt acccatgtaa acgattaaag aatgttcgta
     2221 acaaagcaat tagttttaat ttatcttctt ctttggctaa cgtttgagga tttactttct
     2281 gatttaagag aaccccacct acgatttcat ctgttggtaa ttttgaaaca gattttaaaa
     2341 cagatgtagg gccgtgttga tccatattat gtgatggtga acaaccctct gctaacggtg
     2401 tacccgcgtt gcgtccatct ggagttgcta atgttccacg tccctgccct acgttggctg
     2461 agatagaaga tgttcctgaa taacgaattc ctccaattgg acctcttcca taacgtgtat
     2521 taggatattt agcaatttca tcaacataaa tgtcataagc agcagtaacc aatttgtcag
     2581 cataatcatc atcattacca tacttaggtg catcatgaat caacatttct tgaatgacct
     2641 taccttcttc tccggcataa tctgtttcca gtgcatgcca aagctgactt gggcttatac
     2701 gttcttcctc aaacaccaat tttttaattg cagctaatga atccgacaaa tttgcaattc
     2761 caacttgcaa tcctgatata taatcatata ctgctccacc ttctttaagg tgttttccac
     2821 gaccaataca atcatcagtc aatgctgaac atagaatatc aggaacttct cgttccaatg
     2881 ataaatcaat agaattttca acaataacac tcattcgtgt caaatatctt agtgttttat
     2941 cccaagcatt ttctaattca gaaaagttct tcatatcctt aaaatgacca aagcttggtg
     3001 caaaccgttt acccgaagcc ggatcaattc catcattcat cgtgataagt agaaccttag
     3061 ggaagttcat ataactcata cctgtgcaac gatagcccca tttccctgga actgccgttt
     3121 caacacatcc aatggcactg taatcataag catcatcttc caatactcct tttgcaataa
     3181 aagaaggaat aataatctca tcattattaa atgcaggcat accaaaacca agtttcatca
     3241 cttcaataca ctcattcatg aaacgagcat ctaaacctgc atggtaacgt acagttagat
     3301 taggttgcgg tagatgggtt tgtgcaactg attttaatac caaataagat aatgggttaa
     3361 cagcatcctt cttatctcga gtctgtccac caattgtaac attttgatat aaaggacttc
     3421 ctgctgaaga aaatgtatgt gattgactgc gaaccttatt aattgtaatt gtcttaatcc
     3481 aaagatttgt cagacgttca acaatgctat cttctgtttc tttaccactt tctaaatcag
     3541 ccttcatata tggatacata tattgatcaa aacggccata tgaaagagag tggccattag
     3601 attcaatttg taaaatacat tgaataaacc aaactgattg aatagcttct gcaaaagtag
     3661 ttaccggttc atatgggact ctagagcaaa tatctgcaat ctcaagtaat tctttcttac
     3721 gtttaggatt tgcattttcg gctaaacttt tagcaagagc aacaaagcgc tttgcatata
     3781 ctttaatagc atcgattacg ataaatatag agtcgtaaaa atgatattta tcaatacttg
     3841 ctggatctgt taaatctaga gctgcttttg ctttacgagc ccgctcttca aaacctctta
     3901 agccaaattg caaaagtttc tgatagttaa ctgctaggtg agcatctcca gaattcatct
     3961 taccttccat accgaagaat cctgtttcca tataaacaga cacttcttca ggtaataagg
     4021 caccagctct agcacgtaaa ttattatttt cccaaaacgg agcaatactt ctaagttgtt
     4081 cttttgtttc ttctgtaata tagaaaacat ctccatcacg cttttcaaaa agatccaact
     4141 cattgagaac aaattctagc gtatattccg gaaaaatagg agcatcttta ttggaagaag
     4201 cttgatttcc cccaatcata gattcttctt caatatagat agtcatattt tccaaaattt
     4261 ctttcagcat atatgcacgt tttaggacat taggttgttc cttgtatcgt tcataggcgc
     4321 gtgttgctag aactgctctc tcagcatcaa tataaggttt tttatttaaa acatcttctc
     4381 gatatttgtt catcctttca gtaaggctgc caaaatattc tgtcttgatt gttgttcttg
     4441 ctacttctgt atttaccatc gtaaccacct ttctttcgaa aatattttta tttctttcga
     4501 aaatataata ccgattttta tagaaatttt caagctttta actagaaaaa ttttaactct
     4561 ctaattttta gcacaaatgt gtgagtttaa cagtaacaca caaatacctc taagattgtt
     4621 tgatttcatt ttggtaagct aaacgatcct gtactttaaa gaatggaaaa taaaccaatg
     4681 tagacatcgc taatatcacc agctgagtaa taactccttg ccatccaccc accaaaaatc
     4741 ctgataaaat agctggtgta ctccaaggca atgttacccc tgagaatggc tgcatgaaac
     4801 ctgttgcaat agctccatat actatcacag ctgcaagtac aggaacaaga atgaaaggta
     4861 caaacataac tggattcatg acaatcggaa atccaaatac aactggctca tttacgttaa
     4921 atattgctgg aaaagcggca acttttccta aggcttggta ttgttttgat tttgctgcaa
     4981 aaagcatggc aactacaaga ccaaacgtaa tccctgaacc tgatagaatt aaaaatgaat
     5041 ctaaaaattg ttgagtaaca atatgtgcac cattttctaa tgatagatta ccagaggcta
     5101 acatagcttt attagcatca agattagata aaagcagagc tgtcactact ccatttacta
     5161 ccgattgtcc atgaacacca aaccaccaca aaaatgatat aaagaatgca attccaatag
     5221 caccatacaa agatccagtt aaaccttgca atggaacttg aatagcagaa taaatcattt
     5281 ctatgaatgt tccgccatta gtcaatgact tcgctaaaat atatacaatc atagaaagta
     5341 agaaaattac aaatgctgga atcattgctt caaactgttt ggcaatagct tgtggaactt
     5401 gttctggcat cttaataaca atttttctct ttataaagaa ggtataaata cttcctacta
     5461 ccaaacctat aatgatagca ccgataattc cttgacctcc aaaccaaact ttactaatag
     5521 catccccaat tgcctcacct tgtttaggga tataagatga tcttagcaaa ataaagaatg
     5581 cagatacaga tagaactcca gctggtaaag cctctactcc gctattctta gcataagaat
     5641 aggcaattga aaaacaagaa attagaccca taatagcaaa agttcctgaa tatacttgca
     5701 taaacggctc tgtccaatta gctccaaaaa cactagcaat gctcttattt aatccttcga
     5761 acggcaattg tcccataatc aagaataaac taccaactac tgtcaatggc aaaattgcta
     5821 acatcccatc ttttagagct ataatgccac gcatattcac aaacttcatc atcggtgcaa
     5881 tgattttctg aacatccatc tttgccataa taaatctcct tttcttaccc actaatcaaa
     5941 gatagggcca aatctaatac ttttttccca tctaacatac catagtccat catcggaata
     6001 acagctatcg gaacatcaca cttatcacaa atttcttttg atttatctaa tgtataagca
     6061 acttgtggac ccaatagtgc aacatctata tttggcgcat aatccgctaa tttagactga
     6121 gaaaacgcct ctatttctgc ctcaactcca ctagcttgcg ctgcaatttt catattattt
     6181 acaagcatac cagtagaaaa acctgctgca caaaacaaac caatcttcac cattatgttt
     6241 tcctcctcta tgttaataac aatgataata ctctagtatt attttttatg aagttctttt
     6301 ctcaaactaa taatttcttt gattaaatta atctccgtca tactagtcat gagatgatct
     6361 tgtgaatgaa caaagagagc tgtaatttct gtctttgtac cagacgcttc ctgtgccaag
     6421 aattttgttt gtagattatg agcttctaat aaggctgcat cagctaactg gatttcttct
     6481 tcacatcgtt cacatgtacc attttttatg taatctaacg ctttataaat atgttgtttc
     6541 gcatcgccag catataaaat taaacccatg ataatttgat ctggaacaat aatttccata
     6601 aattcctcct catttcacta tgtaaaaagc ttttttcatt tgaaatttta aaattttctt
     6661 ttgtaactat agaatacaac tacataataa agttgtcaat ccaaaaacaa cagataaact
     6721 atttttgttt atataagcac aaatgtgcaa tcaactaaaa agaaaaacga taaactgaat
     6781 cagtctatca ttttcactca cctagaatct ctctaaaagt caaatcccca tcttcttcca
     6841 aaacttttaa aattgtattt ttgtctgtaa tcaaatgatt tactaaatta gcacgcaaga
     6901 cagaaagaat cgaagatact ttcgtatcac cgtaagcaac agctaaactt tgaggaatat
     6961 tttttaaatc ttccaaagag attgctatcg ttctttcctg taagttttca tagacttctt
     7021 taccttttga atcaaaaaat cgacaacaaa tttctcctac agttttaact ttggtcaatt
     7081 ctttaaagtc atcctctgta agcatgtcta accattgatg ttttccttta ttgctaaaat
     7141 caccaattcc gactacagct atatctaaat ctttccaact atttttcaaa ttttcaaaat
     7201 atcttgattg caaaatacca tctgctaaca atttattttc ttgcacaatc gttgcattca
     7261 taaatgtaca ctctccatga aattttctag acatttcata aatcagtgta ttcacatggt
     7321 atttagcgtg tatgtgacta ggaccacctg ctagaggata gaagtgaaca tttcggacac
     7381 ttttactgtg aattaaatct actaaattac ttaaactttt cccccaagaa aagccaattt
     7441 tcatattatc atcaattaaa ttcctaagga cacctgctgc aacttgagaa attctttcag
     7501 ataaaattgt tggattatca tcaaattcat ttggaataat ttctaaactt tccagaccat
     7561 atttttcttt tacataattt tccaacttaa acatatttgt atcaaaattc tctatttcaa
     7621 ttttaacaat tcctgcattc cttgcttctg ttaacattct actaatagag gttctataaa
     7681 ttcctaattt tgctgctatt tgtgactgat ttaagttttc aatataatac agataagcaa
     7741 ttttagagag cagtttattc ctatcttgat tcatacactt aacctcttac gaaactacct
     7801 taaccattat cccagcattt tctaatgtag ctatattttg tttagaaagt ttttcgtctg
     7861 ttattacttc atagacttga cttaaagcaa atcttcttac tgtacccctt ttatcaaatt
     7921 tacttgagtc agttagtaca atgactttat ccgacgctgc tgaaatatat tgaactacct
     7981 cactgcgcat taaatctttt cctgtaaagc ccatctcttt atcgtaacca tctgtcccaa
     8041 caaaagcttg atgcacatga aaagtctgta tcatttcttt taataaaggt cccacagtaa
     8101 cctgtgaatc cttctgaaac tctccaccaa gaacaataat acgacatgaa tcataagctc
     8161 tcacaaaatt tgctataaaa aatgaatttg ttacaatcgt aacatttctt ttttgcttgc
     8221 aaatttcctc agcaagtaaa gcacaggtcg atccagattc tatcattatt gtttcattat
     8281 ctgacaccaa ttttactgct tcctgaacaa tttttctctt aatttcataa ttaattgaca
     8341 aacgtacatt taagtcatct ccactattta atacagcata tccatgctct ctgtgtaata
     8401 aaccttttga ctctaattta tctaaatctt ttctaatcgt tactttcgat acatttaatt
     8461 tttccgataa tgtattaacg tcgatctttt catattctga tactaattta ataatttgtt
     8521 ccaatctttt cattttacac ctccgtttta ttctaccaaa ataaaaagca aaaaacaaca
     8581 aatcaacctt tcgttcgtaa ttgtttttct ttcgtttttg tgataggata gacttatgaa
     8641 gaggaggaac tcttatggaa atatctaaag gaattatttt taatattcaa cacttttcaa
     8701 ttcatgacgg cccgggtatt cgtacaactg tttttttaaa aggatgtcct ctgcgctgtc
     8761 catggtgttc taatcctgaa tctcaaagaa tgaaacctga aaaaatgaaa gatgctcaac
     8821 gagagaaatt caccttagtc ggtgaagaaa agactgtaga agaaattatt acagaggtat
     8881 taaaagacaa agaattttac gaagaatccg gtggaggttt aactttatca ggaggtgaaa
     8941 tatttgctca gtttgaattt gctaaagcca tcttaaaatc agctaaagaa catcacatac
     9001 acactgccat tgaaactact gcctttgttg atcatgaaaa atttatcgat ttaattcaat
     9061 atgtggattt tatctacaca gacctaaaac attataattc tataaaacat aaaaaagtga
     9121 ctggggtttt taatcaaatg attattaaaa acattcatta tgctttttct caaaataaaa
     9181 ctatcgtttt aagaatccca gttattccta attttaacaa tagtttagag gatgcagaaa
     9241 aattcgctac tctatttaac tcattaaata tcgaccaagt tcaactactc ccttttcatc
     9301 aatttggtga aaacaaatat cgtttattaa atcggaaata tgaaatggat ggagtcaacg
     9361 cacttcatcc tgaagatctt attgattatc aaaaggtatt tctgaaccac catattaatt
     9421 gttatttcta gttcatttcc ttgaaatgct ctagctattt gcagataaca agcatctata
     9481 taaggttatc aaagaagact tccccatgac tctaaatgaa tatatcttac aatatcgcct
     9541 gaaacaagct atagataaga tggctgaatc tcccaactcc cctttaagcg ctatctctga
     9601 ccaagttgga ttttcagact ataaatattt tgccaaagta tttaaaaagt atctccatat
     9661 ttccccaaag aaattgaaat cactcggaag aatagtaaaa taggctattc ttctttttgt
     9721 agagaatttt actctaatat agtgaattga aataagatgt gaacatctct atcaggaaag
     9781 tcaaattaat ttatagaaat attttagcag tcaaagtgta ctgttataga ttcaatacac
     9841 tatagaatag aattgtaggt tttaaaaacg cttacattgt tttaaaataa acttaaataa
     9901 cacaacggag atatcccatc atgaaaaaga aatggatgta ttatgctgct tgttcttcta
     9961 atgaatctgc cgatgacagt tcatctgata aaggagacgg tggttcgcta gtcgtttatt
    10021 gaccaaactc agaggactta attggagcaa ctattcctgc ctttgaagaa aaatatggta
    10081 tcaaagtaga actgattcaa gctggtactg gagaactttt caaaaaacta gagtcagaaa
    10141 aagaagttcc tgtagctgat gttatctttg gtggttctta tacacaatat gctacccacg
    10201 gagaactctt tgaaaactat acttcaaaag aaaatgataa tgttatcaaa gaatatcaaa
    10261 acacaactgg cttctctact ccttatacac tagatggtag tgttttaatc gtccaccctg
    10321 atttaactaa aggcatgaac atcgaaggat atagcgacct tctcaaacct gaactaaaag
    10381 gaaaaatcgc aactgctgac ccagcaaact cttctagcgc ctttgctcaa ttaacaaata
    10441 tgctacaagc tcaaggtggt tacaaagatg ataaggcttg gtcttatgta aaagatcttt
    10501 tcacacttat tgatggtata gtaaaatgaa ataagaacag gacaaattaa tcaggacagt
    10561 caaatcgatt tctaacaatg ttttagaagt agatgtgtac tattctagtt tcaatatact
    10621 ataaaatcgg tttaagttca tctggtgtct ataaagcagt cgctgatgga gaaatgactg
    10681 ttggtctctc ttatgaagat ccagcagtta aactcttaaa tgacggagct aacattaagg
    10741 tagtctatcc aaaagaagga accgtcttcc tacctgctag tgctgctatc gttaaaaaat
    10801 ctaaaaatat ggaaaatgcc aagaaattta tcgattttat tatctctcaa gaagtacaag
    10861 atacacttgg tacaaccact actaaccgtc ctgttcgtaa aaatgctaaa acaagcgaaa
    10921 acatgaaacc aattgacaaa atcaaaacac tcactgaaga ttatgattat gtcatcaaga
    10981 ataaatcaga tatcgttaag aaatacaacg aagtctttac agatatccaa tctaaacagt
    11041 aaaagaggtt cactatgagt gagatcgaaa ttattaacgc caaaaaaatc taccacgatg
    11101 tctctgttat tgagaatttg aacattacaa ttccaaaagg aagtctcttt acccttcttg
    11161 gagcttcagg atgtgggaaa acgacccttc ttcgtatgat tgcaggtttc aacagtatca
    11221 aagatggaga attttacttc gatgatacaa aaatcaataa tatggaaccc agcaaacgca
    11281 atatcgggat ggttttccaa aactacgcta ttttcccaca tttgactgtc cgagacaacg
    11341 ttgcttttgg tcttatgcaa aagaaggttc caaaagaaga attgattcaa cagaccaaca
    11401 agtatcttga actcatgcaa attgctcaat atgcggatcg aaagcccgat aaactcagtg
    11461 gtggacaaca acaacgtgtc accttggcat gcgccttagc ggttaatcta agtgttctcc
    11521 tcatggacga gccacttagt aatctggagg ccaaacttcg cttggatatg cgtcaagcca
    11581 tccgagaaat ccaacacgaa gtgggaatta caactgttta tgtaacccac gaccaagaag
    11641 aagccatggc tatttcagac caaattgctg ttatgaaaga tggggtgatc caacaaatcg
    11701 gccgaccaaa agaactctat cataaaccag ctaatgagtt tgtggcaacc tttatcggac
    11761 gcacaaatat tatccctgcc aatcttgaaa aacggagcga cggcgcttat atcgtctttt
    11821 cagatggcta tgcccttcga atgctagctc ttgatcaggt tgaggagcaa gctattcatg
    11881 taagcattcg tcccgaagag tttatcaaag atgaatctgg agatattgaa ggaactatta
    11941 gcgatagcgt ctatcttgga ctaaatacgg agtatttcat tgagacaggt tttgcctcaa
    12001 aaattcaagt tagtgaagaa tcaacttttg aagaagatct acaaaaaggc aatcgtattc
    12061 gtctacgaat caatacgcaa aaattaaaca tcttttctgc agatggttcc caaaacctga
    12121 taaaaggagt caaccatgga acgtaaaaaa ctaaatattt ggacagcctc ctctttcttc
    12181 atctttctta cctatcttgt ctttctcgtt tatcctatcg ttaccgtgct caagtaagca
    12241 cttatacatg aaggacaatt ctcactagct aattttgtca ctttctttag taaagtctac
    12301 tactctgaga cactagtcaa cagtttcaag gtttccatta ccgctactgt cacttcctta
    12361 gttgtaggaa ccctattagc ttatctcttc tctatgtatg acttcaaggg ggagaaattt
    12421 ctacaaatat tgattatcat tgcttccatg tcagctcctt tcgtaggagc ctactcctgg
    12481 gttctcttgc taggacgaaa tggggtcatc actaaatttt tgacaaatgc ccttcatctt
    12541 ccagctatcg atatttatgg attcaaagga attgtacttg tctttacact gcaactattc
    12601 ccactggtat ttctatatgt tgctggaaca atgaacagta ttgacaattc tctacttgaa
    12661 gcagctgaaa gcatggggtc cttcggattt aagcgtatcg taacggttgt tttacctctc
    12721 ctagttccaa ccttactagc agttccttgc ttgtatttat gagagcattc tcagactttg
    12781 gaacgcctat gttgattggc gaaggatatc ggactttccc tgtcctgatt tatacccaat
    12841 ttattagcga ggttggagga aattctgctt ttgcaattat ggcgattatc attgccttgg
    12901 cgattttcct tatccaaaaa cacattgcaa accgctacag tttcagcatg aatctgctcc
    12961 atccaattga gcctaaaaaa actacaaaag gaaaaatagc tgccatttat gcaacagtct
    13021 acggaattat ctttatctct gttttacctc aaatctactt aatttatacc tctttcctaa
    13081 aaacatcagg tatggtatct gttaaaggtt attctccaaa cagttacaag gtagctttcc
    13141 atcgtatggg atctgctatt ttcaatacca ttcgtatccc tttgattgcc ttagttctag
    13201 ttgttctatt tgcgacattt atctcctacc tagccgttag aaaacggaat ttgtttacaa
    13261 acttaattga cagcctcagt atggtacctt atattgtacc aggaaccgtt ctagggattg
    13321 ccttcatttc ttccttcaat actggtctat ttggaagtgg atttcttatg attacaggga
    13381 ctgctttcat cttgattatg tctctatctg tcagaagatt accttatact attcgctcat
    13441 ctgttgctag cttacaacaa atagcaccaa gtattgaaga agctgctgaa agcttaggaa
    13501 gtagtcgtct caataccttt gctaagatta caactccaat gatgctatct ggtatcattt
    13561 ctggagccat cttatcttgg gtcacaatga tttcaaaact ctctacttct atcctcctct
    13621 acaatgtcaa aacaagaaca atgactgtag ctatttatac agaggttctc agaggaaatt
    13681 acggtgtagc cgcagccttg tcaactatcc tgactgttct aacagtaggt tccttgctct
    13741 tgtttatgaa aatctctaaa agcaatagca ttacacttta gttttccaca tcaaaaacag
    13801 ccgaaaggag taccctcggc tgttttttct tatcttgata ttcttatcaa atccctagct
    13861 catggcaagc aagtctagac tgattaaata gagccttctt ccatcttctc acgtcctagc
    13921 tctcggtaac tacggtcacc gacaacttca accctaaact gaccgtcctc atattcaaga
    13981 atcgtcacgc taccattatc tagaccatgc ggatgcatgc cattaatcag ataaacaatg
    14041 gttccaatag tcattccatg gctgacaaca agggcgttac ctccaccttg atcttccatt
    14101 tcttttgcaa tcatttcaaa gccttccttg attcggccac tgagtttttc ccagccttca
    14161 gcccaaccag ctgtatcgac ctctaccaag ccctcagcca gttcagcata agacaattgg
    14221 tgaacgtggt ccacattaaa gatacgagga ataatgccca tgaaaagatc gccatcatag
    14281 gctccatcaa aactaccgaa acaccattct ctgatacgct tgtccatgcg ataagggatt
    14341 ttcccctgca agccaagttc ttcaaggata attcccatgg tctgaatggt acgaccagaa
    14401 tcactcgaat aagcgcgctc aaactgtaga tcagattctc gcaaaccgat tcctaactct
    14461 tgaatccctc gttcaccttc agcagttaag ggagtatcgc tccaaccttg cgcgcgacca
    14521 atcgtgttaa acatggtctt gccatgacgt accaaataca atcgtacttt taccattttc
    14581 cgtcctccgt ttgcttctat tatatcatga atgataaaat aaaagccacc catacaggcg
    14641 acttttgaag gagattatta tgaaaaagtt taggagttca ttaaataaag atattagatg
    14701 aaaatcaaat tcaaactaat tcagtgttat ctgtttcaaa taatattagg aggtctttat
    14761 ttaatgatta tagtatacac gtctaatctt aaatagaact taaaatttct cctattttct
    14821 taatttttaa aactatgaat tggtgctggg atttgtccac cgcgagagat gaagtcgaca
    14881 gacgaagccc cattaacctt cataacaggt gcagttccta atagaccacc aaactcaatc
    14941 atatcgcctt ctcttccttt gggaatgata cgaacagctg ttgttttcat gttgataaca
    15001 ccgattgctg cttcatccgc aatcatagcc gcaatggttt cagcaggcgt atcttctggg
    15061 atggcaatca tatccaatcc aacagaacag atagccgtca tagcttctag tttttctaaa
    15121 ttaagagagc cattttgcac tgcagcaatc attccttcat cctcagaaac agggataaag
    15181 gcaccagata aaccaccgac ttggttgcag gccatcactc cacccttttt aacttggtcg
    15241 ttcaagaggg ccaaggcagc cgtcgttcca tgcgtgccaa ctgtttctag ccccatttcc
    15301 tcaaggacac gtgccacaga gtctccaacc gcaggggttg gtgccaaact caagtccaca
    15361 ataccaaact ccacacccag tctctcactg gccatttgac caaccaattg accgatacga
    15421 gtgattttaa aggcagtttt cttaactgtt tcggctacta catcaaagct ctgtccacga
    15481 actttttcca aagcacgttt cacaacacca ggaccagaaa ctccgacatt gatgataaca
    15541 tctgcttccc caacaccatg aaaggcaccc gccataaatg gattgtcctc aacagcatta
    15601 gcgaatacaa ccaacttggc cactcccata tctgaaagat ttgctgtttc cttgataatt
    15661 cgtcccatat ctgccacagc cgtcatatta ataccagact tggttgagcc gatattgact
    15721 gacgagcaga ccttatccgt ctcagccaaa gcgcgaggaa tggaattgat gagaatctca
    15781 tctccctttt gataaccttt ttgtactaag gcagaaaaac caccaataaa gtccacacca
    15841 atctctttcg cagccttatc aagcgctttt gccagaacca cgtagtccgt cgcatctgtc
    15901 gctgccccaa tcagagaaat aggtgtcacc gatacacgct tattaacgat aggaattccc
    15961 aactcagccg caatttcatc accaacagct actaaattag ccgcctttgt cgtaattttt
    16021 tgatagattt tctccgcagc acgattgata tttggatcga tacagtccaa aagagaaatc
    16081 cccatggtaa tggttctaat atcgaagttt tgctcctcaa tcatggcgat ggtttcagta
    16141 acttgtctaa tatccatgat gacctcctag atattataca tagcttcgaa aatcgctgca
    16201 ctctgaatat tgatttttac attcaaagtt tgcccaaaag cttcaaattc attacgaaga
    16261 taggtaaaat cttgcttttc atcactagat acaacagcca tcatcgtaaa atattcatcc
    16321 aatacagttt gagagatatc gtcaatattc aatcctaatt ctgcaatttt accagaaaca
    16381 cctgcaacaa ttccagattt atctttacca acaacagtta taatcgcttt cataagtaaa
    16441 ctccaattct tcttaaaata agaaacctta acattaaaca ggattctttt caaatagtat
    16501 agcataattc taacgaaaat actcaaaaac gcctgcttac gaagttgttc ttaagaaaaa
    16561 aacaatttcg taaacaagcg tctactatcc caacttatga tgagtgttcc cgctaggacc
    16621 gaaatcctag cggtagacca gagctagact aagagcacaa gactccatca tcataacact
    16681 caacaaaatt gatgatttta tactaattcg atgatcgcca ttggcgctgc atcaccacga
    16741 cgtggttcag ttttaaggat acgagtgtat ccaccgttac gttcagcata acgaggtgcg
    16801 atttctgaga acaatttttg aagtgctgta gtagaagtgt acttatcagt tgcttcatca
    16861 tagttttcag atgcgatttc attacgtacg aaagcagctg cttgacgacg tgcatgcaaa
    16921 tcaccacgtt tacctagagt aatcattttt tcaacagttt tacggatttc tttagcacga
    16981 gcttcagttg tcacgattga ttcgttgatc aaaaggtcag ttgtcaaatc gcgaagcatt
    17041 gctttacgtt gtgagctagt gcgtcctagt ttacggtaag ccatgtattc ctcctttatt
    17101 tatcttttaa tccaagaccc aaatcaatga gtttgagttt cacttcttcc aaactcttgc
    17161 gtccaagatt tcgtactttc atcatctctg cttcagattt ttctgtcaaa tcatgcacag
    17221 tattgatacc ggcacgtttt aaacagttgt atgaacgcac agacaagtcc agttcctcaa
    17281 tcgtacgatc taaaatacgg tcgtcagatt cagtatcagc ttctttcatc acttcagttg
    17341 acttagcaat ctcagtaaga tttgtaaaca aatcaagatg ttctgtcaaa atacgtgctg
    17401 aaagccctaa agcatcttct ggaataattg ttccatttgt caagatttca agggttaatt
    17461 tgtcgaaacc atcattgcta cctacacgag caggttccac ttgatagttg acttttgtaa
    17521 ctggtgtata aatagaatct acagcaagtg ttccaactgg tgcattatcc tttttatttt
    17581 catcagcagg tacatatcca cgaccactgt taacagtcat agtcgctttt agagaagaac
    17641 cttcaccgat tgtaaagaga taatgatctg gatttacaat ttcaatatcg ctatctgtca
    17701 aaatgtcacc agctgttact tcagcaggac cttcaacatc cagttcgatg attttttcgt
    17761 cttcaacgta cgatttcact gcaattcctt taatgttcag aatgatttgc atcacgtctt
    17821 cacgaacacc tggaactgtg tcaaactcat gtaacacacc atcaatgttg atagatgtca
    17881 cagctgctcc tggtagagaa gctagaagta cacgacgaag agagttacca agagttgtac
    17941 cgtagccacg ttcaagtggt tcgattacaa acttgccata atctttattt tcatcaattt
    18001 ttgttatatt tggtttttca aactcgatca tttagttact ccctcttaaa cgaaaagcag
    18061 tgtaatgcga tgattataca cggcgacgtt ttggaggacg agcaccattg tgtggcactg
    18121 gagtcacatc acgaattgct gttacttcaa gaccagcggc agcaagcgca cgaatagctg
    18181 actcacgacc agaacctgga ccttttacag taacttcaac tgatttaaga ccgtgttctt
    18241 gtgcagattt agcagcagct tcagaagcca tttgagcagc gaatggtgta gatttacgag
    18301 aacctttgaa accaagagca ccagctgatg accaagcaat tgcattacca tgcacatcag
    18361 taatcataac aatagtgtta ttaaatgtag cgtgaatatg agcaatacca gattcgatat
    18421 tctttttcac acgacgttta cgtgttggtt tagccaagac ttttacctcc tatattattt
    18481 tttcttacca gcaatcgcaa cagctttacc tttacgagtg cgagcgttgt ttttagtatt
    18541 ttgtccacgg acaggaagtc cacgacggtg acggatacca cggtatgaac cgatttccat
    18601 caaacgtttg atgttcaagt ttacttcacg acgaaggtca ccttcaactt tgattgcatc
    18661 cacttcacga cggatagcat cttcttgatc tgatgtaaga tcacgtacac gaacatcttc
    18721 tgagattcca gcagcagcca aaattttctt agatgttgca agtccgatac cataaacata
    18781 agtcaatgag attactacgc gtttgtcatt tggaatatca actccagcaa tacgagccat
    18841 gttttctcct ttctatctta tccttgacgt tgtttgtgtt ttggatttgc tgggcaaatt
    18901 accataacac gaccattacg acgaataact ttacagtatt cgcaaattgg tttgaccgat
    18961 ggtcttactt tcatttctta tccctccaag tttttcgatt atttaaagcg gtaagtgata
    19021 cgtccacgtg tcaagtcata tggactcatt tcgacagtaa cacgatctcc cgctaaaata
    19081 cgaatatagt ttttacgaat tttaccagaa actgttgcta aaatctgatg tccattttca
    19141 agttcaaccg taaacattgc attcggcatt gtatcaacta ctttgccttc aacttcaatc
    19201 acatcgtctt ttgccacgca aaagcacctc cataaatttc gatttgatgc ctctagacac
    19261 agagacaaca attataagtc agactatttc agtataacat ttgtagcgga tttttgcaag
    19321 tgtgaaaaac gctttatttc aaatttgtca atactttttc aatatctgag aagacatcat
    19381 tgatatcttg attaccttcg atgtcatgaa ccaaaccttt ggcacggtag tgagcaatga
    19441 ttggttctcc ttgagcaata ttaacatcca aacgacgttt tactgtctca ggcttatcat
    19501 cttcacgttg gtagtaatct tcttctttat agtcaactgg tgggttaaag accttgtgga
    19561 aagtttctcc agttacgcgg tggatgatac ggccactcaa acgttccaag aggctgtcag
    19621 ggttcacttc aatattgata ataccttcta gttcaatgcc aagttcagcc aatgttttgt
    19681 ccaaggcatg agcttgttca attgtacgtg ggtaaccatc caataagaat cctgtttctt
    19741 taatatcatc ttgtgaaagg cgttctttta cgattccatt tgtaacttcg tcaggaacca
    19801 attcaccctt gtcaatatat gacttagcaa gaacacccat ttcagtttga tttgccattg
    19861 cagcgcggaa catatcacct gttgagatat gtgcaacatg gaattgttct acgatttttg
    19921 ctgcttgagt tcccttacct gcaccaggta agcccataat caaaagattc atgatttgat
    19981 ctccttattt tatttttaaa tagaagcaaa aagtcttttc acccctattt aaaaacaaaa
    20041 tagaagaggg gagatccaac tcttacaaat gtcagagttt aaacctccac tccctcagta
    20101 tttactgatt cagtaaatac ttttattctg ttctgtccat gaaaccaaca tacttacgtt
    20161 tcaataggta accttccaat tgcttgattc cttcgatacc tgtagagata atgatcaaga
    20221 gacttgttcc accaaaggca acaacatcag aaagaccaaa tacatcttta gctgcaatcg
    20281 gtaaaatgga aatcacacca agaaagaggg aaccaacagt tgcaagacga cgaagaagtt
    20341 tagacatata ttcttctgta cctttaccag gacgaactcc atggatatag gcaccactct
    20401 tttgtaggct ctctgctgct ttttcaggat taatctgtac aaacgtatag aagaatgtaa
    20461 agagaataat caacaaagca tacatggcaa taccagttgg agaagtagtt gccaacatct
    20521 cttgtgctac ccttacccaa gcccaatcat gacctgtggc actcaaaaac tgaagaatag
    20581 ccgcaggcgc tgcagtaatc gaactggcaa agataacagg gataactcca gcagggttta
    20641 cctttaacgg aaggtaagag ctagatggag caccttgtgc aaccttagta tattggattg
    20701 gaattttgta ttctgcttgt tgaacataag ttgtaaagta aataatcaac aatacagtaa
    20761 taatcaaaat gattacgaaa atgatagatg aagtgatacg gctacttggg acgttcacaa
    20821 agtagtccac atagatgccc tgaatcatct ctggaattga ggaaacaatc ccggcaaaga
    20881 taatcatgga aacaccgttt ccgtatccct tatctgtaat ttgctcaccc aaccaagtga
    20941 caatcatact accagctgtt aagatgatac caatcgtcag aaaaacttgt ggagttaaag
    21001 cagttttaat caattgagct ccagccaagg tattaaaacc agctgtaatc ccgatagatt
    21061 gcacaaaagc gagaactaga gcaatataac gagtagcttg attcaatttt cttcgaccta
    21121 cttccccttg tttaccccac tctacaaact tgggtaaaat atccatttgc aagagttgga
    21181 caacaataga agcggtgata tagggactaa ctcctagggc aaaaatcgaa aagtttttta
    21241 gggcattccc cgacaccaag ctcaacatgt ttaagaagga taatccactt aaagcattca
    21301 agctattggc attcacacca ggaactgtaa tgctagttcc gatacgaaag accaaaacga
    21361 taaaaattgt aaataaaatt tttgatcgaa cctgcttgac tttaagagct tctcttaata
    21421 atttaaaaaa cataggtcac ctctcttaga tgacttctac tgaaccacct ttagcagtga
    21481 tagcttcttc agctgattta gagaatttag ctgctttcac agtcaatttc ttagtcaact
    21541 caccgttacc aagaatttta atacctgact tttcagcttt aacaattcct gcttcgataa
    21601 gaacaactgg agttacttca gcaccatctt caaagacgtt caattggtca aggttcacaa
    21661 ttgcgtattc tttagcgttg atgttagtga atccacgttt tggaagacga cggaacaatg
    21721 gagtttgtcc accttcaaaa ccaaggcgaa ctccgccacc gctacgagct ttttgacctt
    21781 tttgaccacg accagatgtt ttaccgttac ctgatgaagt accacgacca acgcggttac
    21841 gtactttacg agaaccttct gcaggtttca attcatgaag tttcattttt attttctcct
    21901 cttttgtaaa atgctagcgc cgataaggga gaaaaggttg tctcccccat caactcgcct
    21961 atacgatgtc atcatagatg actatatcta gttttagggg atggtacagt gcacatcccc
    22021 taaaacttca ttagtttact tcttcaactg ttactaagtg agatactgct gtaatcatac
    22081 cacggatagc agcgttatct tctttaataa cagagctgtt caatttgcca agtccaagtg
    22141 ctacaacagt tttacgttgt gatggaatgc gtccgattgg agacttagtc aaagtaattt
    22201 taatttgagc cattttatcc cctttcttat gccaaatcag aaactgaaat accacgaagg
    22261 gcagcaattt cttcagcgcg tttcaattgt ttcaaacctt caacagttgc acgaacaatg
    22321 ttgattggag tgttagaacc aagtgattta gatgtaatat ctgccacacc tgccaattcc
    22381 acaacggcac gaactgcacc accagcggca actccagaac cttctacagc aggtttcaac
    22441 aatactttag ctccaccgaa ttctgaaaga acttcgtgtg ggattgttgt tccaaccata
    22501 ggaacttcga tcaagttttt cttagcatca tctactgctt tacggattgc ttctggaact
    22561 tcttgagctt taccagtacc aaatcctacg cgaccattgt ggtcaccaac aacaacaaga
    22621 gctgcgaaac gaagacgacg tccaccttta acaacttttg taacacggtt gacagcaact
    22681 acgcgttctt ctaattcaac tgcattgtct ttaaatgcca ttttctagtg tcctcctatt
    22741 agaatttcaa tccgttttca cgagctgcat cagccaaagc tttcacacgt ccgtgatata
    22801 gatatccacc gcggtcgaac accacttctg aaataccttt agcgtttgca cgttctgcaa
    22861 cgagtttacc gacagcaacg gcttgttcag ttttagttcc ttttgaaact tctttatcaa
    22921 gagttgaagc acttgcgagc gttacacccg ctacgtcatc aatcacttga gcgtagatgc
    22981 ctgtattaga acggaatacg ttcaaacgtg ggcgatcagc agttccagag agttttccgc
    23041 gaacgcgacg gtggcgtttt tggcggagtt tgtttttatc tggttttgaa atcacagttt
    23101 tcacctcttt agttttaaat cgtgtgctat gcacaaagtt ggaaaatagg ttggtggttg
    23161 atgatcaacc actcaacatt atttacctgt tttaccttct ttacggcgaa cgaattcacc
    23221 aacgtaacgg atacctttac ctttatatgg ttctggtgaa cgaaggctac gtacgtaagc
    23281 agctgtttga ccaactactt cttttgaaat tccgctaaca acgattgttg ttgggtttgg
    23341 aagttcaaaa gtaattcctt ctggagcttc aacttcgtct ggatgagatt taccaacagc
    23401 caaaacaagt ttagatcctt gaagctgtgc acggtaacca accccacgca tttcaagttc
    23461 tttcttgaat ccttctgata caccaacaac catgttgttc aaaagggcac gagtagttcc
    23521 gtggatagtt ttcatttctt ttgaatcgtt tggacggtga agagttattt cagtaccttc
    23581 cacacggatt tcaatatctt ttgagaactc acgagtaagt tctcctttag gtccttttac
    23641 agttacaacg ttgtcattgt tagcgagttc aacaccagca ggcaacacga taactttatt
    23701 accaatacgt gacatgttta ttttctcctg ttaaattgtc aggccagaac ggccagtttt
    23761 cacggggttc agatacttat ttagttcaag agctgaactg aacacgctct aagaactgtg
    23821 caaaatagat aagttggctt gtttgtaaac aaacttctcc aacttcctaa ttttgctttg
    23881 ttctttacga gctttgtatc ttgattttac caaacgtaag cgataacctc accaccaaca
    23941 ttcttttggc gtgcttcttt atcagtaagc aaaccttcag aagttgaaag gatggcaatt
    24001 ccaagtccgt taagaacttt tggaaggtct tcacgttttt tgtagacacg aagtcctggt
    24061 ttagaaacac gtttcaagtt agtgataact ttctcaccat ttggtccgta tttaagaaat
    24121 acacggatga cgccttgttt gtcatcttca atgatttcaa cgttttttac aaaaccttcg
    24181 cgtttaagga tttcagcaat cccttttttg atgtttgatg caggtacttc aagtacttcg
    24241 tgtttagctt ggttagcatt acgaatacga gttaggaagt ctgcgattgg gtcagtcata
    24301 accattttgt ttttctcctc ttactagtag tttgcaagtt gcacttgcta gttaatacat
    24361 gatacaaaga gcgtaacagc acgagcaaaa atagacaatt taatgcagaa gcaatgctcc
    24421 aaagcaaatt agtctttttt gccaaagctg tagctcgtgt tcaaattggc aagcccaatt
    24481 gaacccgggc taaactctgt gtgaaaaaga taaactttcc tagaaacttt agtttcttcg
    24541 tcaagtttcc tatttttact tggagttttg acgctcttga tatcttaaat taccaagatg
    24601 cttttgttac accaggaatt tgacctttat gcgcaagttc gcgaaaagcg atacgactca
    24661 gaccaaattt gcggtaaact gaatgtgggc gccccgtaac cctacaacga ttatgtaaac
    24721 gagtcggtga ggcgttgcga ggtaatttag ataaaccttc gtagtcccct gccgccttta
    24781 atgcagcacg tttttcagca taacggtcaa caattttttg gcgtttagcc tctctagcta
    24841 ccattgattt tttagccatt agatttacct cctatattat tttgcaaaag gcattccaag
    24901 gcctgtaagc aatgcacgtg actcttcgtc agtgttagca gttgttacga taacgatgtc
    24961 aagaccacga gttttgtcaa cgtcatcgaa gttgatttct gggaagatta attgttcttt
    25021 cacaccaagt gtgtagttcc cgcgtccatc aaatgatttt gttgggacac cgtggaagtc
    25081 acgtacacgt ggaagtgaaa ctgataccaa tttatccaag aattcgtaca tacgttcacc
    25141 acgaagggta acttttgcac cgatcgcaac accttcacga agacggaagc cggcgattga
    25201 ttttttagct ttagtgataa gtggtttttg acctgagata agtgccaatt cttcagcagc
    25261 tttttcaagg cttttagcgt ttgatacagc ttcaccaaca cccatgttca aaacaatctt
    25321 atctacttta ggcacagcca tcactgatga gtagttgaat tgttctgtca aagcaggaac
    25381 tacttcatta agatattttt cttttaaacg atttgccatt atacttctcc tttccttcgt
    25441 gattaatcaa gcacttcgcc tgattttttg ttgtagcgaa cttttttacc gtctacaaat
    25501 ttgtaaccaa cacgaccagc tacaccattt ttgtccaaaa cttgaacatt tgatacgtgg
    25561 atagctgctt ctttctcgat gataccacct tgaggaagct cgttagttgg acgttggtgt
    25621 ttcttaacaa tgttaacacc ttcaacgata actttgttta cttttggaag ggcagtaagg
    25681 acaacagctt ctgttccctt atctttacca gcgattacgc gaactttgtc gccttttttt
    25741 acaaacatta ggtttctcct tgatttttct tacgcccata agggcaccct agcttgaagc
    25801 taggggacta gtttgttcct aaaaattaaa gtacttctgg agcaagtgac acgatcttca
    25861 tgaaaccacc ttcacgcaat tcacgtgcaa ctgggccaaa gatacgtgtt ccgcgaggag
    25921 ttttgtcttc acggatgata actgctgcgt tttcgtcaaa tttgatgtat gaaccatcag
    25981 cacgacgagc acctgattta gtacgaacga taactgcttt aacaacgtca ccttttttaa
    26041 ccgcaccacc aggagtagct tgttttacag atgccacgat aacatcaccg atgtttgcaa
    26101 atttacgtcc tgaaccacca agaactttga tagtcaagat ttcgcgagca ccgctgttgt
    26161 ctgcgacttt caaacgagtt tctgtttgaa tcatttcagt tttctccttt caggtttgat
    26221 tagatgatga ccgcttcttc aacaacttct acaagacgga aacgttttgt agctgaaagc
    26281 gggcgagttt ccatgatacg tacgatatcg ccttctttgg caacattgtt ttcatcatga
    26341 gctttgtatt ttttagagta gttaatacgt ttaccataga ctgggtggtt acgttttgtt
    26401 tcaactacaa ctgtgattgt cttgtccatt ttgtcagata caacacgtcc aacaagaact
    26461 ttacgattat tgcgttccat tgaaatttct ccttccctag tctattattt cgcttcagat
    26521 tgaactgttt tgatacgagc gatttgtttt ttaacttctt tcaagcgagc tgtttgttcc
    26581 aattgaccag tagcagcttg gaaacgaagt tcaaacaatt cttttttcaa ttcgttttcg
    26641 cgcttcgcga gttcttcttg agaaagacca cgaagttctt taacaaattc ttttacttca
    26701 ttaagtttca tgccttctcc ttattctgct tcacgtttta cgaatttaca tttaactggc
    26761 aatttgtggc tagcaagtcg aagcgcttca cgtgcaatct cttcagatac accagcgatt
    26821 tcgaacatca ctttaccacg tttaactggt gctacccaac cttcaggtgc ccctttacca
    26881 gatcccatac gcacaccgat agctttagca gtgtatgatt tgtgtgggaa gattttaatc
    26941 caaactttac caccacgttt catgtaacga gtcatggcga tacgagcagc ttcgatttgg
    27001 cggttagtga tccagtggct agttgtagct tgaagaccgt attcaccgaa tgctacttct
    27061 tttccacctt ttgcttcacc gcgcattttt ccacggaact cacgacggtg tttaacacgt
    27121 ttaggtacta acattggtta tttacctcct ttagtgtttt tacgagctgg aagaacttca
    27181 ccacggtaga tccatacttt aacaccaagt ttaccgtatg tagtatctgc ttcttcccaa
    27241 gcgtaatcga tatctgcacg aagtgtgtga agcggaacag ttccttcaga gtatccttca
    27301 gcacgggcga tatctgcacc gttcaaacga cctgatactt gagttttgat tcctttagct
    27361 ccagcacgca ttgcacgttg gattgcttgt ttttgtgcac gacggaaagc aacacgttgc
    27421 tccaattgac gagcaattcc ttcacctaca aggtgagcat ccaaatcagg ttgtttgatt
    27481 tcgatgatgt tgatgtgtac ttgttttcca gtcaatttgt taagttttgc acggagtgca
    27541 tcaacgttag caccaccttt accgataacc atacctggtt tagcagtgtg aagtgaaacg
    27601 ttaactttgt ttactgcgcg ttcgatttca atagttgaaa ctgctgcgtc agcaagttct
    27661 ttttgaacga atttacggat tgcaagatct tcatgaaggt aatccgcgta ttctttttca
    27721 gcataccatt tggcatccca atcacggatg atgccgacac gcataccaat tggatgtact
    27781 ttttgaccca cgattttacc tccttatttt tctgcaacag ctacagtgat gtgagctgta
    27841 cgtttgttga ttggtgaagc tgaacctttc gcacgtggac ggaaacgttt catagttggt
    27901 ccttcgtttg cgaatgcttc agatactacc aagttagctt tatccaaacc aaagttgttt
    27961 tcagcgttag ctacagctga gttcaaaact ttcaagatga tttcagcagc tttgtttgga
    28021 gtgaatgtca agattgcgat tgcatcggct acgcttttac cacggatgtt atcaagaaca
    28081 agacgtgatt tacgaggtga aacacgtact gtacgagcca ttgctttagc tgaagtaatt
    28141 tctgccattt atgttctcct tattttctac gtgttttctt gtcgtctgca gcgtgacctt
    28201 tgtaagtacg agttggtgca aattcaccaa gtttgtggcc taccatgtct tcttggatgt
    28261 aaacaggtac gtgtttacgt ccgtcataaa ctgcaatagt gtaaccaatg aaacttggga
    28321 agatcgttga acgacgtgac caagttttaa taactttttt cttttcgtcg ttagcttgag
    28381 cttcaacttt tttcatcaaa tgctcatcga cgaaaggtcc ttttttaaga ctgcgtccca
    28441 tttttatatt ttctccttta aatgttgtac cacagcggct tgcactccta tggagcgcta
    28501 ccgagctggc ggatttacta gttgcttaag cgactagttt aatattattt ctcgttgcga
    28561 cgacgaacga taagtttgtc agatttcgct ttcttgttac gagttttaag accaagagca
    28621 ggtttgcccc atggagtaga tggtgcttta cgaccaactg gtgctttacc ttcaccacca
    28681 ccgtgtgggt gatcgttagg gttcattaca gaaccacgaa ctgttgggcg gatacctttc
    28741 caacggctac gtcctgcttt accaaggttt acaagtccat gttgttcgtt tccgacaaca
    28801 ccaactgtag cacggcaagt tccaagaatc atacgaactt cacctgattg aagacgaaca
    28861 agaacatatt taccttcaga acccaatact tgagcagatg caccagcagc acgtaccaat
    28921 tcaccaccac gacctggttt caactcgatg ttgtgaatca aagtaccaac tgggatgtta
    28981 gcaagtggaa gagcgtttcc gactttgata tctgcttctg gacctgaaac gatacgttga
    29041 cctacttcaa gaccttttgg agcgatgatg tatgctttca caccgtcagt gtagtgtaca
    29101 agagcgatgt ttgcagaacg gtttggatcg tactcgattg ttttaacaac tgcttcaacg
    29161 ttgtctttat tacgtttgaa gtcaaccaaa cggtagaaac gtttgtgtcc accaccttgg
    29221 tgacgaactg tgatacgacc gttgttgtta cgaccagcct tgctcttcaa tgcaacaagc
    29281 aatgattttt caggagtgct tgttgtgatt tcagcgaaat ccaaagaagt catattacgg
    29341 cgaccgtttg ttgttggttt ataaacacga attcccacga tatttcctcc ttagattatt
    29401 cagcttcagc agcaaacaac tcgattgctt tagaatcagc tgtaagtgtg atgatagctt
    29461 ttttagtttt gttagtaaaa ccagtgtaac gtccaacacg tttagctttt ggttttacgt
    29521 tgattgtgtt aacattggca actttaacac cttcgaaagc agcttcaaca gcttgcttga
    29581 tcaaaagttt gtgtgcacga gtgtcaactt caaatacata tttccctgct tcaagttgag
    29641 ccattgagct ttcagtgatg acaggttttt tgataacatc atacaaattc attatgcaag
    29701 aacctcctcg attttagaga tagctgcttg tgtgacaaga agtttgtcgc tatttgcgat
    29761 gtcaagaaca cttgcagttg tagcagttgc aactttcacg tttggaaggt tacgagctga
    29821 aagagctgcg aattcatttc cttcttcaag gataacaaga actttagaat cgatgctcaa
    29881 tgctgcaaga acttttgcaa attcagcagt ttttggagct gtaaatgaaa gagcgtctac
    29941 agctacgaat ttgttttcag caactttttc agagtaaact aatttaagag ctaggcgacg
    30001 aactttttgt ggaagtttgt agccgtatga acgtggagtt ggtccgaaga caacaccacc
    30061 accacgccat tgtggtgagc ggatagaacc ttgacgagca cgtccagttc ctttttgacg
    30121 ccatggtttg cgtccaccac ctgatactgc agagcggttt ttaacagcgt gtgttccttg
    30181 acgaaggctt gcgcgttggc tgatgattac atcaaacaca actgattcat ttggttcgat
    30241 accaaatact gcatcgttaa gaacaacttg gccagcttct ttaccagttt ggtcaaataa
    30301 tgttacgttt gccattgtga ctgatttccc ctttctttat tatttaccag ctttaactgc
    30361 tgatttgata gtgataagag atttcttagc acctggtacg ttacctttga taaggataac
    30421 gttcttttct ggaacaactt gtacaacttc aaggttttga attgttacgc ggtcgccacc
    30481 catacgtcct gcaaggtttt tacctttgaa tacgcggtta ggtgcaacag gccccataga
    30541 acctggacga cggtggtaac gagaaccgtg agccattggt ccacgtgatt gtccgtggcg
    30601 tttgataaca ccttggaaac ctttaccttt agaagtacca gttacatcaa caacatctcc
    30661 agctgcgaat gtttcaactg tgatttcagc gccaacttcc aagccttcaa cgtttttgaa
    30721 ttcacgaatg aagcgcttag gagccgtgtt agctttcgct acatgtcctt tagcaggttt
    30781 gttgctcaat acttcgcgtt tgtcatcgaa accaacttgg atagcgttgt atccgtctgt
    30841 ttcaacagtt ttaacttgaa gaacaacgtt tggagttgct tcaataactg ttacagggat
    30901 caattcgcca gcttcagtga agatttgagt cattcccact tttttcccta agattccttt
    30961 tgtcatgaga aaatagttcc ttttctatat tttttattca aaaagttttt aacgagcgtt
    31021 ttttatgctc aagtctaaga tacaaagggc gtcaaactca aagtgaaaat aggaaactaa
    31081 cgcagtgtct agcggacaat aggaagttta tctttttcac accgagttta gcccgtgttc
    31141 aattagattg aaacaccagc ctctgctctt ttatatttta gattaaagtt tgatttctac
    31201 gtttacacca cttggaagat ccaatttcat caaggcatca actgtttttt gagttgggtt
    31261 aacgatatcg atcaaacgtt tgtgtgtacg catttcaaat tgttcgcgag agtctttgta
    31321 tttgtgagtc gcacgaatga ttgtgtagag gctacgttca gttggaagtg ggattggacc
    31381 cgcaacttgt gcacctgtac gagtagctga ttctacgatt tttgcagccg ctgtgtcaag
    31441 cgtacggtgt tcgtaagctt tcaaacggat acggattttt ttgtttgcca tctttttctc
    31501 cttttcgtct atttaagata ataggctagc tccacaagaa aaccgacgcg gtgttgcgtg
    31561 gcaatgcaac cgagcgtgtc gcaacctctt gcatcaaaac taaggctgta atttacagca
    31621 ccataataga ataacacaaa tcccctgcga ttgcaaggga tttgttaggt tttttcgttt
    31681 ttttgggatg aaactgtttt cctacttttt ctttctaaaa ttagggattt tcttctatat
    31741 ttcttctata cataagttaa gtcctcttga catcaaattt atcttctgat tggtccacta
    31801 agatatccgc cttagactca gtttctttat agtatcgcag atactgctcc cgtctcatct
    31861 gatggctagc caatataaag gatgcatagc gatttctcac agtcgtatct ctagcaaggc
    31921 gtcgctttaa ttcggtctcc tcatccgtgt agaaacagat ggttttttca aagagttcct
    31981 tgggtagaaa accaacagac atcccttcga caatcaaaat tggtttggct ccagacaaga
    32041 cctcactagc cttccaaggt tcttcaattg tcaagacatc catacccgcc tgcaaggcaa
    32101 ggatatctct ctgcaaactc tccagttcat gcgccactgg cagactggct gtcacctttt
    32161 gattcggcgc gtccttgggt actaccaaat agcgtccgga ggtgatatag ggatctgttt
    32221 ctagcaaatt ta
//
LOCUS       DBERAE010000023        31791 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.23, whole genome shotgun sequence.
ACCESSION   DBERAE010000023 DBERAE010000000
VERSION     DBERAE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.23"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(90..1331)
                     /gene="pbp3"
                     /locus_tag="ACL70N_001241"
     CDS             complement(90..1331)
                     /gene="pbp3"
                     /locus_tag="ACL70N_001241"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGS0590043.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            1434..2543
                     /gene="cozE"
                     /locus_tag="ACL70N_001242"
     CDS             1434..2543
                     /gene="cozE"
                     /locus_tag="ACL70N_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGS0590044.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            3189..3536
                     /gene="ssrA"
                     /locus_tag="ACL70N_001243"
     tmRNA           3189..3536
                     /gene="ssrA"
                     /locus_tag="ACL70N_001243"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(3719..3806)
                     /locus_tag="ACL70N_001244"
     tRNA            complement(3719..3806)
                     /locus_tag="ACL70N_001244"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3770..3772),aa:Ser,seq:gga)
     gene            3968..4708
                     /locus_tag="ACL70N_001245"
     CDS             3968..4708
                     /locus_tag="ACL70N_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0590045.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPAVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            4705..5616
                     /gene="pfkB"
                     /locus_tag="ACL70N_001246"
     CDS             4705..5616
                     /gene="pfkB"
                     /locus_tag="ACL70N_001246"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGS0590046.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            5613..7565
                     /locus_tag="ACL70N_001247"
     CDS             5613..7565
                     /locus_tag="ACL70N_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS0590047.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YVAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            7702..9954
                     /locus_tag="ACL70N_001248"
     CDS             7702..9954
                     /locus_tag="ACL70N_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGS0590048.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGSSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(9999..10427)
                     /locus_tag="ACL70N_001249"
     CDS             complement(9999..10427)
                     /locus_tag="ACL70N_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGS0590049.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            10565..11707
                     /locus_tag="ACL70N_001250"
     CDS             10565..11707
                     /locus_tag="ACL70N_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS0590050.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDGVQALTKIPTEKYLTERVDFATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            11716..12930
                     /gene="thiI"
                     /locus_tag="ACL70N_001251"
     CDS             11716..12930
                     /gene="thiI"
                     /locus_tag="ACL70N_001251"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGS0590051.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            13065..13870
                     /locus_tag="ACL70N_001252"
                     /pseudo
     CDS             13065..13870
                     /locus_tag="ACL70N_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            13892..14631
                     /locus_tag="ACL70N_001253"
                     /pseudo
     CDS             13892..14631
                     /locus_tag="ACL70N_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            14644..15810
                     /locus_tag="ACL70N_001254"
     CDS             14644..15810
                     /locus_tag="ACL70N_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS0590052.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            16070..16195
                     /locus_tag="ACL70N_001255"
     CDS             16070..16195
                     /locus_tag="ACL70N_001255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590053.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDRVSIIYLRQGEADVV"
     gene            16318..17811
                     /locus_tag="ACL70N_001256"
     CDS             16318..17811
                     /locus_tag="ACL70N_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS0590054.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            17824..18933
                     /locus_tag="ACL70N_001257"
     CDS             17824..18933
                     /locus_tag="ACL70N_001257"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0590055.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            18963..22248
                     /locus_tag="ACL70N_001258"
                     /pseudo
     CDS             18963..22248
                     /locus_tag="ACL70N_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            22519..22719
                     /locus_tag="ACL70N_001259"
     CDS             22519..22719
                     /locus_tag="ACL70N_001259"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590056.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(22834..23304)
                     /locus_tag="ACL70N_001260"
     CDS             complement(22834..23304)
                     /locus_tag="ACL70N_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0590057.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(23321..25594)
                     /locus_tag="ACL70N_001261"
     CDS             complement(23321..25594)
                     /locus_tag="ACL70N_001261"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGS0590058.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            25940..29041
                     /locus_tag="ACL70N_001262"
     CDS             25940..29041
                     /locus_tag="ACL70N_001262"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGS0590059.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVDQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            29124..30131
                     /gene="pfkA"
                     /locus_tag="ACL70N_001263"
     CDS             29124..30131
                     /gene="pfkA"
                     /locus_tag="ACL70N_001263"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGS0590060.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            30190..31695
                     /gene="pyk"
                     /locus_tag="ACL70N_001264"
     CDS             30190..31695
                     /gene="pyk"
                     /locus_tag="ACL70N_001264"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGS0590061.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         9662 a         5617 c         6928 g         9584 t
ORIGIN      
        1 tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg aacttgtatc
       61 aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa gcggacaaac
      121 tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc taccatttcg
      181 aaactagggc gctctgtggt gatgtaacct tgaccaatca agtccttgtc ttcataagtc
      241 aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga atcaggtgtg
      301 aattgaacag attgggaaga ttgattccca acacgttcga ttagatagat atcctctgga
      361 gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct atcttgatag
      421 gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata atccattagg
      481 gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc atttaaaaca
      541 actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc tccagcctta
      601 tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat accttctaac
      661 atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag aagatggttt tttggtgatt
      721 tctaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac atcataagca
      781 ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc tagagtttca
      841 ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc caagagtttt
      901 gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc tagggcaata
      961 gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac agtataatta
     1021 cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata aggataatca
     1081 gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc atagaccaga
     1141 taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc atccttctca
     1201 tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc aatggtaaaa
     1261 tcttgagcaa cagcagtaga agcaccccct aaaagagaga cagttaacaa agttaaaaat
     1321 atttttttca tagtagtctt attctatcat aaagaaaaaa aatattcttg ctttaataat
     1381 tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa ctcatgtttc
     1441 gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc atcttttacc
     1501 tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat acaattatga
     1561 ttccattttt attagggggc tttctttatt atttgacaaa ccctattgtt actttcttaa
     1621 ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt actttggtct
     1681 ggggaatggt cataggtgtt gtctatctct tacctatttt gattaatcag ttatctagtt
     1741 tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata gacttatcta
     1801 attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta aacttatcct
     1861 atgttgatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg agcgtcttgt
     1921 cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg gtttatttct
     1981 tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag agggatcgct
     2041 tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat attagtggag
     2101 tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt attattggtt
     2161 taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt ccttatgtgg
     2221 ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat ccccatagac
     2281 tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat atcttatatc
     2341 ctcgaattgt aggaagtgtt atgaaggttc atccaatcac gattttagtt ttacttttgt
     2401 tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc tattctatct
     2461 tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata atgaaagaac
     2521 gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt actggaagtg
     2581 gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc acagctaaga
     2641 atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg tcagggtaag
     2701 ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttatag tatattgaaa
     2761 ctagaatagt acacctctaa ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
     2821 tattcgtcct attcttattt cattttacta tattttggtg caataagtga aaagtagtcc
     2881 gaataatata aggattgatt ttatagtttt taaactcaaa tgaattaaaa taaagagagt
     2941 acgaaaattc tcatctgaaa gtattttaga ataattttct tcgtgaattt cttcaaaaca
     3001 gatagcttca tcttaggtat gtgttaattg gatttcgtaa gctctattta caatcgtaaa
     3061 gttatgcact gagaaagttg tagttagtct tccagtttgc taaatttctc gaatagtatc
     3121 ttttttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata atggttttat
     3181 tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg cgactcgtgt
     3241 ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta cgctctagct
     3301 gcctaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga caggtcttat
     3361 tattagcgag atacgattaa gccttgtcta gcggcttgat aagagattga tagactcgca
     3421 gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac ctatggttgt
     3481 agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct ccattattcc
     3541 tttgcattct tttgcattcc ttggtaaaac gttgttaaat caacgttttt tatttttatc
     3601 tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc ctattttaaa
     3661 aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct tttttccacg
     3721 gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt ccaacacggc
     3781 ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca taaaggctct
     3841 tatcttgcaa taaaaattct agaaatatga aaaatgatag attttgaaag aaaatgataa
     3901 aaaatgcttg acttcgaaag aaagtatgat agaatgaata gtgtaaacga taacaggagg
     3961 tgattcagtg ttaaaaacag aacgtaaaca actaatttta gaggagttaa atcaacatca
     4021 tgtagtttct ctagaaaaat tagttagttt gctagaaacg tcagaatcaa cggttcgaag
     4081 agacttggat gagttggaag cggaaaacaa gcttcgtcgt gtgcatggtg gagcagaact
     4141 cccccactcc ttacaggaag aagaaaccat tcaagaaaaa tctgtcaaaa accttcaaga
     4201 aaagaagttg ctggctcaga aagcagcctc tctcattaaa gaaaaagatg tcatctttat
     4261 cgatgctgga acaacaactg cttttttgat tcatgaattg gtcaataaga atgttacagt
     4321 tgtgaccaac tccattcacc atgccgctca gttggttgaa aagcagattc cagctgtcat
     4381 ggttggagga aacgtcaaga cggcgacaga tgctagtatc gggggcgttg ctcttaacca
     4441 gattaaccaa ttgcactttg accgtgcctt tatcggaatg aatggtgttg acgatggcta
     4501 ttatacgact cctgatatgg aggagggagc tgtgaaaaga gctattttgg agaatgccaa
     4561 gcagacctac gtcttggtgg attcgtcaaa aattggacaa acttgctttg ccaaggtagc
     4621 accactcaaa cgcgctatcg ttatcactag tcaagggcat gagctcttgc aggttattaa
     4681 ggagaaaacg gaggtaatag aagtatgatt tatacagtca cactcaatcc atccattgac
     4741 tatatcgttc gtttggacca agtcaaagtt ggtagtgtaa atcgtatgga cagtgatgat
     4801 aagtttgctg gtgggaaagg aatcaatgtc agccgtgtct tgaaacgttt gaatatacca
     4861 aatacagcga cgggatttat cggtggcttt actggtaaat ttatcacaga tactttagca
     4921 gaggaagaaa tcgagacacg ttttgtccag gtggcagaag atactcgtat caatgttaaa
     4981 atcaaagcag accaagaaac agaaatcaac ggaacgggtc caactgttga atcggttcag
     5041 ctagaagaat tgaaagctat tttatctagt ctgacagcag aagatacagt tgtctttgca
     5101 ggttcaagtg ctaaaaatct aggcaatgtt atctataagg atttgatttc cttgacgcgc
     5161 cagactggtg cgcaagtggt ctgtgacttt gaaggacaga ccttaattga tagtttggac
     5221 taccagcctc ttcttgtaaa accaaacaat catgaacttg gagcgatttt tggggttaaa
     5281 ctcgaaagtt tagatgaaat tgagaaatac gctcgtgagt tactggctaa gggtgctcaa
     5341 aatgttatta tctctatggc tggggacggt gctcttcttg tcacatctga gggagcttac
     5401 tttgctaaac caatcaaagg aacagtcaaa aattcagttg gggctggtga ttctatggtt
     5461 gctggattca caggtgaatt tgtcaaatca aaagacgcag tagaagcctt caaatgggga
     5521 gtggcttgcg gaacggcaac taccttctca gatgacttgg caacggcaga acttattaaa
     5581 gaaacatatg gaaaagttga ggtagaaaaa cgatgaaaat tcaagaccta ttgagaaaag
     5641 atgtcatgtt gctagatttg caggcaactg aaaaaacagc tgtcatcgac gagatgatta
     5701 aaaatttgac agaccacggt tatgtaacag attttgaaac atttaaagaa ggaattttgg
     5761 cgcgtgaagc tttgacttct actggtttgg gtgatggaat cgcaatgcct cacagcaaaa
     5821 acgctgctgt caaagaagcg acagttctat ttgctaagtc aaataagggt gttgactacg
     5881 agagcttgga tggacaagca actgacctct tcttcatgat tgcagctcca gaaggtgcca
     5941 atgatactca cttggcagcc ttggcagaat tgtctcaata cttgatgaaa gacggttttg
     6001 cagacaaact tcgtcaagca acatctgcag accaagttat cgaacttttt gaccaagctt
     6061 cagaaaaaac tgaggaactt gttcaagcac ctgctaatga ctctggtgac tttatcgtag
     6121 ctgttacagc ttgtacaaca ggtattgccc acacttacat ggcccaagaa gcccttcaaa
     6181 aagtagctgc tgaaatgggg gttggtatca aggtcgaaac caacggtgct agcggtgttg
     6241 gaaatcaact aactgcagaa gatatccgta aggctaaagc tattatcatt gcagcagaca
     6301 aggccgttga aatggatcga tttgatggaa aaccattgat caatcgtcca gttgctgacg
     6361 gtatccgtaa gacagaagag ctaattaact tggctctttc aggagatact gaagtctacc
     6421 gtgccgctaa tggtgcaaaa gctgcaacag cctctaacga aaaacaaagc cttggtggtg
     6481 ccttctacaa acacttgatg agtggtgtat ctcaaatgtt accattcgtt atcggtggtg
     6541 gtatcatgat tgcccttgcc ttcttgattg acggtgcttt gagtgttcca aatgaaaacc
     6601 ttggcaatct tggttcttac catgagttag cttctatgtt catgaaaatt ggtggagctg
     6661 cctttggttt gatgcttcca gtctttgcgg gttatgttgc ctactctatt gctgaaaaac
     6721 caggtttggt agcaggtttc gtggctggtg ctattgccaa agaaggtttt gcctttggta
     6781 aaattcctta tgtcgcaggt ggtgaagcaa cttcaactct tgcaggtgtc tcatctggtt
     6841 tcctaggtgc ccttgttggt ggatttatcg caggtgcctt ggttcttgcc atcaagaaat
     6901 acgttaaagt tcctcgttca ctcgaaggtg ctaaatcaat ccttctattg ccacttcttg
     6961 gaacaatctt gacaggattt gttatgctag ctgtgaatat cccaatggct gcaatcaaca
     7021 ctgctatgaa tgacttccta ggtggtcttg gaggaggttc agctgtcctt cttggtatcg
     7081 tccttggtgg aatgatggct gttgacatgg gtggaccagt taataaagca gcttatgtct
     7141 ttggtacagg tacgcttgca gcaactgttt cttcaggtgg ttctgtagcc atggcagcag
     7201 ttatggctgg aggaatggtg ccaccacttg caatctttgt cgcaactctt cttttcaaag
     7261 ataaatttac taaggaagaa cgtaactctg gtttgacaaa catcatcatg ggcttgtcat
     7321 ttatcactga gggagcgatt ccatttggtg ccgctgaccc agctcgtgcg attccaagct
     7381 tcatccttgg ttcagcagta gcaggtggac tcgttggtct tactggtatc aaactcatgg
     7441 cgccacacgg aggaatcttc gttatcgccc ttacttcaaa tgctctcctt tacctcgttt
     7501 ctgtcttggt aggagcaatc gtaagtggtg tggtttatgg ttacctacgc aaaccacaag
     7561 cataaaaaat agaaaaatga aaagattgga ccgtttggtg cagtcttttt ctcttcccga
     7621 aatgcctgtg aaatatggta taatagaaga atggcaaaca agaatacaag tacaacaaga
     7681 cggagaccgt ctaaagcaga actggaaaga aaagaagcga ttcaacgaat gttgatttcg
     7741 ttaggaattg cgattttatt gattttcgca gccttcaaat taggggctgc aggtataacc
     7801 ctttataatt taattcgctt gctagtgggt agcctagctt atctggcgat attcggccta
     7861 ttaatctatc tcttcttttt caagtggata cgaaaacagg aaggactctt atctggtttt
     7921 ttcaccatat ttgctggctt actcttgatt tttgaggcct acttggtttg gaaatatggt
     7981 ttggacaagt ccgttctaaa agggaccatg gctcaggttg tgacagatct gactggtttt
     8041 cgaacgacta gctttgctgg agggggcttg atcggggtcg ctctttatat tccaacagcc
     8101 tttctctttt caaatatcgg aacttacttt attggttcta tcttgatttt agtgggttct
     8161 ctcctagtca gcccttggtc tgtttacgat attgctgaat ttttcagtag aggctttgcc
     8221 aaatggtggg aagggcacga gcgtcgaaaa gaggaacgct ttgtcaaaca agaagaaaaa
     8281 gctcgccaaa aggctgagaa agaggctaga ttagaacaag aagagactga aaaagcctta
     8341 ctcgatttgc ctcctgttga tatggaaacg ggtgaaattc tgacagagga agctgttcaa
     8401 aatcttccac ctattccaga agaaaagtgg gtggaaccag aaatcatcct gcctcaagct
     8461 gaacttaaat tccctgaaca ggaagatgac tcagatgacg aagatgttca ggtcgatttt
     8521 tcagccaaag aagcccttga atacaaactt ccaagcttac aactctttgc accagataaa
     8581 ccaaaagatc agtctaaaga gaagaaaatt gtcagagaaa atatcaaaat cttagaagca
     8641 acctttgcta gctttggtat taaggtaaca gttgaacggg ccgaaattgg gtcatcagtg
     8701 accaagtatg aagtcaagcc ggctgttggt gtaagggtca accgcatttc caatctatca
     8761 gatgacctcg ctctagcctt ggctgccaaa gatgtccgga ttgaagcacc aatccctggg
     8821 aaatccctaa tcggaattga agtgcccaac tccgatattg ccactgtatc tttccgagaa
     8881 ctatgggaac aatcgcaaac gaaagcagaa aatttcttgg aaattccttt agggaaggct
     8941 gttaatggaa ccgcaagagc ttttgacctt tctaaaatgc cccacttgct agttgcaggt
     9001 tcaacgggtt cagggaagtc agtagcagtt aacggcatta ttgctagcat tctcatgaag
     9061 gcgagaccag atcaagttaa atttatgatg gtcgatccca agatggttga gttatctgtt
     9121 tacaatgata ttccccacct cttgattcca gtcgtgacca atccacgtaa agccagcaag
     9181 gctctgcaaa aggttgtgga tgaaatggaa aaccgttatg aactctttgc caaggtggga
     9241 gttcggaata ttgcaggttt taatgccaag gtagaagagt tcaattccca gtctgagtac
     9301 aagcaaattc cgctaccatt cattgtcgtg attgtggatg agttggctga cctcatgatg
     9361 gtggccagca aggaagtgga agatgctatc atccgtcttg ggcagaaggc gcgtgctgca
     9421 ggtatccaca tgattcttgc aactcagcgt ccatctgttg atgtcatctc tggtttgatt
     9481 aaggccaatg ttccatctcg tgtagcattt gcggtttcat caggaacaga ctcccgtacg
     9541 attttggatg aaaatggagc agaaaaactt cttggtcgag gagacatgct ctttaaaccg
     9601 attgatgaaa atcatccagt tcgtctccaa ggctccttta tctcggatga cgatgttgag
     9661 cgcattgtga acttcatcaa ggctcaggca gatgcagact acgatgagag ttttgatcca
     9721 ggtgaggttt ctgaaaatga aggagaattt tcggatggag atgctggtgg tgatccgctt
     9781 tttgaagaag ctaagtcttt ggttatcgaa acacagaaag ccagtgcgtc tatgattcag
     9841 cgtcgtttat cagttggatt taaccgtgcg acccgtctca tggaagaact ggagatagca
     9901 ggtgtcatcg gtccagctga aggtaccaaa cctcgaaaag tgttacaaca ataaaaaaat
     9961 agcttctttc cgagtttgga gggaagctat tttagtggct attgattgct tttattttct
    10021 gaagttggcg cattggactg tttttcgttt tcagtagcag gtttacttga agcaggagta
    10081 gaagagtcct gagttgctgt tttctgatct tcttttttct cttccttgac gctagatttt
    10141 ggtgtttcct cttgctgtgt tttttcttga ctagtgttag tctctttagt tggactggtg
    10201 ttttccttag gggattcctt ttggatttct ttgacaatgg ttgtcgtctg gcttgtcgta
    10261 ggttcttttt taatattttt gttattatcc aaggcgttca taatcgtgat acttgcggta
    10321 atcaagccaa ggatactagc gattgtagca acggtttttt gaaagactgt aaagcctttt
    10381 ttgatgtgtt ctgtttttgg ttttgaagtt ctacgatagt tagacataca ttctctcctt
    10441 tgattatgat ttattatact ctgtttcttt aaaaaaatct taaaaaaaga gaaattgccc
    10501 tttcttgtcg caagctccgt ttcatgatac aatagaggaa gtgattttag aaagcgtgag
    10561 aaacatgatt tactttgata attcagcgac gaccaagcct tatcctgaag cccttgaaac
    10621 ctatatgcag gtcgcttcaa aaattttagg aaacccatct agtctccata gtttgggaga
    10681 ccaagcaaca cgaatcttag atgcttctcg ccaacagatt gcagatttaa tcggtaagaa
    10741 aagcgatgaa atcttcttta cctctggtgg aacagaaggg gataactggg ttatcaaggg
    10801 tgtggccttt gaaaaagctc agtttggcaa gcacatcatt gtttcagcca ttgaacatcc
    10861 agcagtcaaa gagtcagccc tctggttgaa aagtcaagga tttgaagtgg attttgctcc
    10921 agttgataag aaaggcttgg tcgatgttga ggcgttagca ggtttgatac ggcctgatac
    10981 aatcctcgtt tctatcatgg ctgtgaacaa tgaaatcggc tctatccaac ctattgaggc
    11041 tatttcagaa ttcttggcag acaagccgac tatttccttc cacgttgatg gggttcaggc
    11101 gcttaccaag attccgactg aaaagtatct gacagaacga gtggattttg cgactttctc
    11161 tagtcacaag ttccacgggg ttcgaggtgt tggctttgtc tatatcaaat ctggcaagaa
    11221 gattacacct cttcttacag gtggtggcca ggagcgagat tatcgttcga caactgaaaa
    11281 tgtggcaggg attgcagcga cagccaaggc cctccgtttg tctatggaaa agctagatat
    11341 ctttaggagc aagactgggc agatgaaggc agtgattcgc caagctcttc tgaactatcc
    11401 ggatattttt gtcttttcag atgaggaaga ctttgcacct catattctga cttttggaat
    11461 caaaggtgtt cgaggtgaag tcatcgttca cgcctttgaa gactatgata ttttcatctc
    11521 aacaacctca gcttgttcat ctaaggcagg aaaaccagcc ggtaccttga ttgccatggg
    11581 agtggacaaa gataaggcca agtcagctgt gcgtcttagc ctagacttgg aaaatgatat
    11641 gagtcaggtc gagcagtttt tgaccaagtt aaaattgatt tacaatcaaa ctagaaaagt
    11701 aagataggag cattcatgca gtattcagaa attatgattc gctacggaga gttgtcaacc
    11761 aagggtaaaa accgtatgcg tttcatcaat aaacttcgta ataatatttc ggacgttttg
    11821 tctatctata cccaagttaa ggtaacagca gatcgcgacc gtgcccacgc ttacctcaat
    11881 ggagctgatt acacagcagt tgcagaatct ctcaaacaag tttttggaat tcaaaacttt
    11941 tctcctgttt ataaggttga aaaatctgta gaagttttga agtcttctgt ccaagagatt
    12001 atgcgggaca tctacaagga aggtatgacc tttaagattt ctagcaagcg tagcgaccac
    12061 aactttgaac ttgatagtcg tgaactcaac caaacacttg gaggggctgt attcgaagcc
    12121 attccaaatg tgcaagttca aatgaaaagt cctgacatca atcttcaggt ggagattcgt
    12181 gaagaagcag cctatctttc ttatgaaacc attcgtgggg ctggtggttt gccagttgga
    12241 acttcaggta aagggatgct catgttgtca ggagggattg actcacctgt agcaggttat
    12301 cttgctctta agcgtggggt ggatatcgag gcagttcact ttgctagtcc accatatact
    12361 agtcctggtg ccctcaagaa agcgcaggac ttgacccgta aattgaccaa gtttggcgga
    12421 aatatccagt ttatagaggt gcctttcaca gagattcaag aggaaatcaa agccaaagcg
    12481 ccagaagctt atttgatgac tctaactcgt cgctttatga tgcggattac tgaccgtatt
    12541 cgtgaggtac gaaatggttt ggttatcatc aatggggaaa gtctaggtca agtagccagc
    12601 caaacccttg aaagtatgaa ggctatcaat gctgttacca acactcccat cattcgtcct
    12661 gtggttacca tggacaagtt ggaaatcatt gacatcgccc aggaaatcga tacctttgac
    12721 atttcaatcc aaccgtttga agactgttgt accatttttg caccagatcg tccaaaaaca
    12781 aatcctaaaa ttaagaatgc ggagcagtac gaagcgcgta tggatgttga aggcttggtt
    12841 gagcgagcag tggctggaat catgattact gaaatcacac ctcaagccga aaaagatgaa
    12901 gttgatgact tgattgataa tctactctaa ttcagaaaat ccaaaagaat agcgaaaatc
    12961 agtaaaaaaa gttagttttt tctctaaaaa caggtaaaaa actaactttt tttattttta
    13021 tgatataatg atataaaatt ttgaatatag agagttttct gacaatgaat caatcctact
    13081 tttatctaaa aatgaaagaa cacaaactca aggttcctta tacaggtaag gagcgccgtg
    13141 tacgtattct tcttcctaaa gattatgaga aagatacaga ccgttcctat cctgttgtat
    13201 actttcatga cgggcaaaat gtttttaata gcaaagagtc tttcattgga cattcatgga
    13261 agattatccc agctatcaaa cgaaatccgg atatcagtcg catgattgtc gttgctattg
    13321 acaatgatgg tatggggcgg atgaatgagt atgcggcttg gaagttccaa gaatctccta
    13381 tcccagggca gcagtttggt ggtaagggtg tggagtatgc tgagtttgtc atggaggtgg
    13441 tcaagccttt tatcgatgag acctatcgta caaaagcaga ctgccagcat acggctatga
    13501 ttggttcctc actaggaggc aatattaccc agtttatcgg tttggaatac caagaccaaa
    13561 ttggttgctt gggcgttttt tcatctgcaa actggctcca ccaagaagcc tttaaccgct
    13621 atatcgagtg ccagaaacta tcgcctgacc agcgcatctt catctatgta ggaacagaag
    13681 aagcagatga tacagacaag accttgatgg atggcaatat caaacaagcc tatatcgact
    13741 cgtcgctttg ctattaccat gatttgatag cagggggagt acatctggat aatcttgtgc
    13801 catccatagt gaaatccctt ggtcagaaaa tctaccagat tgtctgagat tttttgcaga
    13861 aaaatggtaa gttaagaaag gaaaaaacga aatgcatatt gaacatctta gccactggag
    13921 tggtcatcct aaccgtgaaa tgtaccttaa ccgttatgga catggtggga ttccagttgt
    13981 ggtctttgct tcatcaggtg gtagtcacaa cgaatactat gattttggca tgattgatgc
    14041 ctgtgcttcc tttatcgagg aaggccgtgt ccagttcttt accctatcta gtgtggatag
    14101 tgagagctgg ttggctactt ggaaaaatgc tcatgaccaa gcggaaatgc accgtgccta
    14161 cgaacgttat gtgattgagg aggccattct tttatcaagc acaagacagg ttggtttgat
    14221 ggcatgatga cgacaggttg ctctatggga gcctatcatg cacttaattt cttcctccag
    14281 catccagatg tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt
    14341 gtcggtgatt actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg
    14401 aaccaaaacg acggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg
    14461 gggcttggag cctgggaaca agatggttta ccatcctttt acaagctcaa agaagccttt
    14521 gaccagaaac aaattccagc ctggtttgct gaatggggac atgatgtcgc ccacgactgg
    14581 gaatggtggc gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta
    14641 cctatgaatt accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc
    14701 gaactagcta ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg
    14761 gatgagccct tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata
    14821 gatgaagtca aacgtgcagt tgcttttctc ttttataaac atggtccaat tgaccgcatc
    14881 gagtctcaca atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt
    14941 tttggtgcca aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt
    15001 ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt
    15061 gatcaagcag tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga
    15121 gcagccgcaa cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg
    15181 gaccattcaa ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt
    15241 gacgggctcg tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat
    15301 acaccgcttg acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg
    15361 gatcctaaac tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg
    15421 tttttccata ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac
    15481 cgccctgcag gtggttttac cattgatgtt tataactttg ctcattcctt ggacctttat
    15541 cgtggctatg cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag
    15601 tattgtttgg ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg
    15661 cttgccaaat atagccagca gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa
    15721 cttcaaggag attacctgta tatgctgaca actccgagtc gacaagaaat ggatcagatg
    15781 attgctgatt tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttcactccct
    15841 taatcctttt gttttgtctg gtaaaaaata agagcatcct aacaaggtag ctatcataaa
    15901 acttgttcga taactatttg aagcaggatt aggtggctag aaattgaatt ttaacatttc
    15961 aattgagtca tagtattgtg ttttcgtatc cttaaatcag ctaaaaggat ccatgacgac
    16021 acctatacga tatagttttc aggataccaa acaagtctat taatactcaa tgaaaatcaa
    16081 agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag
    16141 aactgacaga gtcagtatca tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga
    16201 ttttcgaaga gtataaaata ttcaggtgac gcatagatat agttaattga agctttgttt
    16261 gaaatctgat aaaataatga tattactaag ttctaaaaac taaagaaaag ggaagatatg
    16321 attacaggcg aattaaaaaa taaaatcgat cagctgtggg aaattctttg gacagaagga
    16381 aacgcaaatc ctttaacaaa tattgaacag ttgacttatc tcttatttat gaaagatttg
    16441 gatagtgtcg agcttggacg tgaaagtgat gctgaatttc tagggattcc ttatgaggga
    16501 gtttttccaa aagataaacc tgaataccgt tggtcaactt ttaaaaatat aggagatgct
    16561 caggaagttt atcgtttaat gactcaggag atttttccgt ttattaaaaa tctcaagggg
    16621 gatacagatg atacagcctt ttcacgatat atgcgagaag ctatttttca aataaataaa
    16681 cctgctacgc ttcaaaaggc aatttctatc ttagatgttt ttccaactag gggattagat
    16741 gtagattttg ataatgacaa acaaagtatt actgatatcg gagatatcta tgaatatctg
    16801 ttatcaaaat tgtcgaccgc aggtaaaaat ggacagttcc gtacacctcg tcacatcatc
    16861 gatatgatgg ttgagttgat gcaaccgact atcaaagata tcatctcaga tcccgctatg
    16921 ggttctgctg gcttcttagt atctgctagc cgttacttaa agcgtaagaa agatgaatgg
    16981 gaaaccaata cagataatat caatcatttt cataatcaga tgtttcatgg aaatgatacg
    17041 gatacgacta tgttgagact tggggcgatg aacatgatgc tacatggagt agaaaatcca
    17101 caaatcagtt accttgactc gctgtctcaa gataatgaag aagccgataa atatactttg
    17161 gttttagcaa atcctccttt taagggctca cttgactaca attcaacctc taatgacctt
    17221 cttgcaaccg taaaaaccaa aaaaacagaa ttactctttc tttctctttt cttgcgaact
    17281 ttaaaaccag gtggacgagc agcagttatc gtacctgatg gtgtcctttt tggttcgtct
    17341 aaagctcata aaggaattcg tcaggaaatt gtagagaatc ataagcttga tgctgtaatc
    17401 tcaatgccta gtggtgtttt caagccttat gctggagttt caactgccat tctcatcttt
    17461 acaaaaactg gtaatggtgg tactgacaaa gtctggtttt acgatatgaa agcggatggt
    17521 ttaagtttgg atgataagcg acaaccgatt agcgacaatg atattccaga tattatcgaa
    17581 cgctttcatc atcttgaaaa agaagcagaa cgtcagagaa cggatcaatc tttctttgtt
    17641 ccagttgctg agataaagga aaatgattat gatttgtcta tcaataaata taaagagatt
    17701 gagtatgaaa aagttgagta tgaaccaaca gaggtcatct taaagaaaat caatgattta
    17761 gaaaaagaaa ttcaagctgg cttggctgaa ttagaaaaat tactcaagta gggaggtggc
    17821 tgtatgaaaa aagtgaagtt gggggaagtc ttatctctaa aaaaaggcaa gaaagccact
    17881 gtacttgctg aacaaacaac tctaagccaa cgttatattc aaatagatga tttaagaaat
    17941 aataataatt taaaattcac tgaaagttta aatatgactg aagcactccc agatgatatt
    18001 ctgatagcat gggatggagc taatgcagga acagttggtt atggattatc gggagctgtt
    18061 ggtagtacaa ttacggtctt aaaaaagaat gagcgataca aagaaaaaat tatatcagat
    18121 tacttgggag tctttttgga aagtaaatcg cagtatttac gagaacattc aacaggtgca
    18181 acaattcctc atttaaacaa gaatatatta cttgatttac aattagaatt gctaggtatc
    18241 gaagaacaag agaacattat ctgtattctt aatacgatta aaaggcttat tactaaaaga
    18301 aaattgcagt tagatgaact aaacttgctc gtcaaatccc gatttaacga gatgtttggg
    18361 gaaaataaaa tatttgaaag cattgataac ttatttgata ttatagatgg tgataggggc
    18421 aaaaattatc ctaaatcaga tgagttgttt agtgaggagt actgtttatt tttaaataca
    18481 aagaatgtta ctaaaaacgg attttcattc gatacaaagc aatttatcac taaaacaaag
    18541 gataaattac ttcgaaaagg caaacttgag cgttatgata tagtcttgac aacaagaggt
    18601 actgttggaa atgtagcgta ctacgatgaa ttaataaaat ataaacattt acgtataaat
    18661 tcaggtatgg taatattacg tcccaagaca ccaaatctaa atcagaaatt tattatccat
    18721 gttttaagga ataataatta tagtcgagtg atatcaggaa gtgctcagcc tcagttacca
    18781 attacaaaat taaaaaaaat acttctcccc ctccccccac tagccctcca aaatgagttc
    18841 gcagactttg tagtccaggt cgacaaatca caatttgctt gtgagatagc tataaaagtg
    18901 tggagaaata gcttgaaatt tagtataata tagctaaact atttatttaa agtgagaaaa
    18961 aaatgggaaa ttttagcttt cttttaaaaa atgacgaata tgaatctttt tcaaaacctt
    19021 gcattgaagc tgagaatatg attgctacat caactgtggc tactgccttt atggcgcgtc
    19081 gtgctttaga gcaggctgtc cattggatat atagtcacga ttcatattta gaagctccct
    19141 atcgtgctac tctatcttct ttagtatggg atgatgattt tagggatatc gtagattctg
    19201 aactccacaa gcagatagtt ctgttgattc ggtggggaaa ccatgctgct catggtggtg
    19261 aaattaagga acgagaagcg attttagctt tgcatcattt gtatcagttt gttaatttta
    19321 tcgattattg ttacagcaat gagtttgtgg agcgttattt tgatgagaag tgcttaccac
    19381 tttcagcaaa catcaaatac cgagaaactc cacaatctat gataaagtta caagacagtt
    19441 taccagaact gcctgatttt catgaacaga tggctgctca gtccgtagaa gttcaagaga
    19501 cttatactga aaaacgtgag actgcagcgc aacggcaaga tgtgcctttc catattgatc
    19561 aattatctga ggcagagaca agaaagctct ttattgatat cgatctccgt ttagcaggat
    19621 ggatatttga agaaaactgt cgtgttgaga tagccgttga tggtctcaag cacggttcag
    19681 gaattggtta ctgtgactat gtactttatg gtaaaaatgg gaaaatttta gcgattgtgg
    19741 aggctaaaaa agcctctgtc aatccagaag taggggaagt acaggtcaaa gaatatgctg
    19801 aagctttgga gaaacatatc ggctatcagc caatttgctt tattacaaat gggttgaagc
    19861 actatatact tgatggtccg aaccgccgcc agattgcagg cttttactct caagaagaat
    19921 tgcaattagt gatggataga cgtcatcttc aaaaaccgct tgaggatatt tctagtaaaa
    19981 ttagggacga tatttccggg cgtcactacc aaaaacatgc cattgcaagc gtttgtgaag
    20041 ctttctctga tcatcgtaga caggcacttt tggttatggc aactggggcg gggaaaactc
    20101 gtacagcagt ttctctagtt gatatcttat cacgtcataa ctgggtaaaa aacgttctct
    20161 tcttagccga tagaacttcc ttggttaagc aagcctatga ttcgtttaga aaattactcc
    20221 cagatctttc cgtttgtaac ttcttagaag ataaagaagg agctcaatca agtcgtatgg
    20281 tcttttcaac ttatccgacc atgattggag cgattagtgg tcaagaagaa gtaaatcaac
    20341 gcccttttac tgttgggcat tttgacctta tcataattga cgaatctcac cgttctattt
    20401 atcagaaata caagtccatt tttgattatt ttgatgcaag gattgtaggc ttaacagcta
    20461 ctccgcgtca agatttagat aaaaacacct atggattctt taatttggag aatggggttc
    20521 caacatatgc atatgatttg gaagaggctg ttaaagacgg atatttagta gcctatcatt
    20581 ctatcgaaac caaactgaag ctacctacgg atggtctaca ttatgatgat ttgtccgaag
    20641 aagaaaagga acattttgat agcaaatttg aagacgatag ctgtgaaaaa gatattgatg
    20701 ggagtgtgtt taattccttt attttcaata aaagtacagt agaaattgtt ttaaatgaac
    20761 tcatgacaag aggaattcag acagcctcgg gtgatgaaat tggtaaaact attatttttg
    20821 ctaaaaatca tgaccatgcg gaatatatca gaggtatttt taacaaccgc tatcctgaaa
    20881 aagggagcga ctatgctcag gtgattgatt atagtattaa gcattatcag accttgattg
    20941 atgattttaa aattaaggag aagtatcctc aaattgcgat ttctgtcgat atgttagata
    21001 caggtattga tgtaccagag gttgttaatt tagtcttctt caagaaagta cgctctaaaa
    21061 ctaagttttg gcagatgatt ggtcgaggaa cccgtctatg taaagattta tttggacctg
    21121 agcaggataa gaaaaacttc ttggtatttg attatgggga caattttgat tattttcgtg
    21181 cagatccaag agatggagag ggtcgtcaca ttgtttcgct gactcagcgt ttatttaata
    21241 tcaaagtgga cttgattcga gaacttcagg gactccaata ccaagaagat cagtttgcga
    21301 gagcataccg tcagcagctt gtctcggaac ttcaaggtcg tatagagagc ttaaatgagt
    21361 tggacttcag ggttcgtatg gttttagata cagtttatag ctataggaaa ttggaaagtt
    21421 ggcagaatct aactgctgtt acaagtgaaa ccattcaaaa aaatctctct ccgcttttat
    21481 ttgatgaaga taaagaagat gagatggcga ggagatttga tttgtggttg cttcatattc
    21541 agttggggca actgacagct aaatcttcca ctgttcatat ttcccaagtg atgaagacgg
    21601 ctagagctct ttctgctatt ggcaatatcc cgcaggtttt tgagcaggct gaaattatca
    21661 gggaagtaca ggagcctgaa ttttggaaag aagttaactt gtctgatttg gaaaaaattc
    21721 gtcttgctat tcgagattta ttacagtttt tggataaaac agaccgtaaa ccctactatg
    21781 ttaactttga agatcgtata ctctccactg ttcacgagac cacagcattt ttgcaggtca
    21841 acgatcttcg gtcttacaat gaaaaagttg acatctgatg atatgcttgc acttgaaaaa
    21901 ttgctttggg aaaaattagg tagtaaagca gactaccaaa gtcattatga aaataaggca
    21961 attccgagat tggttcgtga gattattggc ttagatagag agtctgccaa tcgtattttt
    22021 tctaaatttt tgtcggatga gaatcttaat gccaggcaga tttcatttgt aaaattgatt
    22081 gtagactaca ttgtagaaaa tggtttttta gagacgaaag tgttaacgca agagccgttt
    22141 aaatcttatg gttctgttca actactcttc caacaccaac taccagtact tcgtaatatt
    22201 gttcaaatca ttgaacttat caataatcga gctggagaag cggcttaaat tctaaagtga
    22261 ttgccatgct gagactcatt taaaattaaa aagagtagaa atttatgata tatatgagaa
    22321 gttttattag gaagaatgtc atcgtttttc tagaatacag tatcagttgt taagtggctg
    22381 ataaatttca aagtagatac ttgtaccacg atgtttgttg atcgagttat taacaaaaga
    22441 gctactttga ttttaaagaa atagaaaaca aaaagccgag caagaattca attgcaggag
    22501 aaaatgaaat aatactcaat gaaaatcaaa gagcaaacta ggaaactagc tgcaggctgc
    22561 tcaaaacact gttttgaggt tgtagataag actgacgaag tcagctcaaa acatggtttt
    22621 gaggttgtag atgaaactga cgaagtcagt aaccatacct acggcaaggc gacgttgacg
    22681 cggattgaag agattttcga agagtataaa tcttcctagg ataaagcaaa acgcatagta
    22741 tcaagggttt tcaacacttg atactatgcg ttttctgatg ttaaagactt tctaccagtt
    22801 tttttaagca taattgttag ttgtagtcat ttattattct tcaaagaaaa atggtggggc
    22861 gaattttttc agttcttcaa agcacttttg agcagtatct gcatcttcac agatgataag
    22921 acagacatca ttaccacaaa gggtagcgat agcgtcaggg aagctcaaag tatcaatgat
    22981 agaaccaaag gattgagcca gtccaggaag ggtttttagt aggacttggt gttgaactgg
    23041 gcgcatccag acaagggcgt cttccatgta gagttcgaga cgtttttccc attttgagat
    23101 ggaaccattg ttaagaacat aataagcgct atcttcttcg cggacttttg ataggttcat
    23161 atttttgatg tcgcgtgaga gggttgcctg ggttacttga atgtcgttct tagcaagaag
    23221 ggcttgcaac tcagcctgtg tatgaatctt gttttttgtg ataagagcgc gtataagttg
    23281 gtggcggtgt tctgatttat tcataataat gtaactcctt ttagcaaggt aaggtaagca
    23341 tggactgagc gaggtcgaca gtcaagtggt agtctgtatt gtcacggatg gtgatttcaa
    23401 agtcagtagt atagaggact aaacggagag tgtctccttc ttttagcttg taaatagttg
    23461 gctgcagttc aaattgaacg tccatccatt catctgcagt aatatcctct actaacagta
    23521 aatcatttct attttgtaaa ttaaggtaac cttttgtcac gactcgttgt gcctctggtc
    23581 taaatggcaa ttcacagaga ttttccaaca tgtgatagcg accgttgtca atggttctag
    23641 cacttaaaat agctggataa ggttgtaggt atttcttttg cccaaattct agcagttggg
    23701 cagataagag ccccttgttt gtactggatt tgatacgaag attgagctga gcgcgaccat
    23761 ttaggtggag atctttagtc acaggaaggt taatagtaat ctgattggct ttcccttgat
    23821 agagctctgt attgaaggtt tggtatgtct taccatagcg ctcaaaatcc ttatctgggt
    23881 actggttttg aatagcttgc tcttcttgac caagtgagaa ggtttcacag ttttcttgcc
    23941 caccgaagtt atcaagtgat aaccaagtct gtggagctgt attgtcctgc cagataacag
    24001 taggaagttg aaagtctgtt tcctgtccta gtaatttctt ggtcaataag gcatttatgg
    24061 actcacggaa gtcaattgat tgccaattgt tcatgtaaac atgagcacca ttatggaaaa
    24121 agagatgctt gtgtatatga gtaggaagag catggaacat ctggtaaaca tgaagtggtt
    24181 tgacattcca atcctgagaa ccatgagtaa agacaacctc tgcctttact ttatgggcat
    24241 tgagcagata attgcggtca tgccaaaact gattgtagtc cccagttttt cgatctagct
    24301 gagctttcac tttttctaag tcagcttggt gagcttcatt gccacggata tagtcgccag
    24361 ctaagagatt acgagaatag gttaactcag caagggagtc aaagtcctca cctggataac
    24421 cacctgggct agtcaccaga ccgttttcac ggtagtagtt gtaccatgat gaaattcctg
    24481 cctcggcaat gataacttct aaaccatcga ctcctgtagt cgcaagacca ttggacatgg
    24541 tacctagata ggaaagtcct gttgtagcaa cttttccgtt tgaccaatca gccttgactt
    24601 gacgctggcg cgtgtgatca gtaaaggcac ggcaacggcc gttaagccaa tcgatgacat
    24661 ttttataagc ctcgatttgc tggtagtctc cattagtcat gaaacctgtc gagtctttgg
    24721 taccaacacc tgagacatag agattggcaa agcctctcgg aaggaagtag tcgtttagtg
    24781 tatagctaga gttgatgtga gttagctttt cctcagcctc tgctataagc tcagctttac
    24841 cttggggttg gacgagattt agttgaggtt tctctagctc aatcttgtga ggaagcttaa
    24901 cctcaagctc gccctccatc ttgtagagag ccttgtcact agccttgtca ttggttccct
    24961 gatgataagg gctggctgtc atgatggcag ggatttttcc atcaaaacga gggcgaataa
    25021 tgctaacctt tactaggtct ggtagccctt tttggtcagt atcgacacga gactcaacgt
    25081 aaacgacttc acgaatgaca tcctggctag aaaaagtagc caaactcttg ccgttaaagt
    25141 agtggtagtc attatcctcc ggaataagac catcactaac aagttggtcg ataagagtat
    25201 ttcctttttt ggtgcgagta tttagtaact gatagagatt ttcaatcaag tcaccatata
    25261 taatgggaaa tccagtttct ttacgaaaaa cgtcactatc ttcgaagtca accaaataag
    25321 aaaagcctaa aagttgaaaa gcaacagtat aaaaaatatc tgctgtcagt tcatcttctg
    25381 attgaaaaaa tgtcagcagg tctgtttttt tatcagctgc taggatagaa agtgggtagt
    25441 tggtgtcttg ataagtgaaa aagaaacgac gtaaaaaggt ttcaagtgag tctttgtgat
    25501 tggctgtatt ttgtaaatca aagccacatt tttttagttc agataagaca ttttcttttg
    25561 gaaaattgat ataactatat tgattaaaac gcatagaacc tccatataga atgacagtta
    25621 aggttattat atcaaaaaaa aagcagaaag ggaattgtta acttcaaaag gaaataatcc
    25681 aataaaaatg aataaagtac taaattcaat atagagaaca gagtaacaat aagaataata
    25741 gatagggtat aaaagttcta ggagatttat attatatgct ttctgttttt atatacaata
    25801 tagtataaat ataaaaatga tgacaaaaat acaaatgaat agaaaataaa ttagtaagct
    25861 gatgaaattt ttctcaagag aagccattta taggtgaaaa tggtataata tagtgagaag
    25921 gatagaggag aagtgtaaat tgatcgcaca actagataca aaaacagtct atagttttat
    25981 ggaaagcgtc atttcgatcg aaaagtatgt gagagcagct aaagaatacg gctacactca
    26041 tttggctatg atggatattg acaatcttta tggcgctttc gactttctag agattacaaa
    26101 aaaatacggc attcatcctt tgctagggct tgaaatgaca gtgtttgtag atgatcagga
    26161 agtgaatttg cgttttttag ctctatctag tgtgggctat cagcagttga tgaagctttc
    26221 gacagccaag atgcaggggg agaaaacttg gtcagtcctg tcccagtacc tggaggatat
    26281 cgcggtcatt gtgccttatt ttgatagagt tgagtcgtta gaactaggct gtgattacta
    26341 tataggggtt tatccagaaa cactagcaag cgaatttcat catcctatct tacctcttta
    26401 tcgggtcaac gcttttgaaa gcagggatag agaagttctt caagttttaa cagcgattaa
    26461 agaaaatcta ccgctcagag aagttccctt gcgttcgaga caagatgtct ttatatcagc
    26521 aagttcttta gagaaactat tccaagagcg ttttccgcaa gctttggaca atttagaaaa
    26581 gcttatttca ggcatttctt acgacttgga tactagtctg aaactgcctc gttttaatcc
    26641 agctagacca gcagtagagg agttgagaga gcgtgctgaa ctggggcttg ttcagaaggg
    26701 gttgactagt aaagaatatc aagatagact agaccaagaa ttgtctgtta ttcatgatat
    26761 gggctttgat gattatttct tggttgtttg ggatttgttg cgttttggac gatcgaatgg
    26821 ctattatatg ggaatgggaa ggggttctgc agtaggcagt ttggtttctt atgccttaga
    26881 catcacgggg attgacccag tagagaaaaa tctgattttt gaacgctttc ttaatcgtga
    26941 acgctatacc atgcctgata ttgatattga tattccagat atttatcgtc cagattttat
    27001 cagatatgtt ggtaataaat atggtagtaa acatgcggca caaatcgtta ctttttcaac
    27061 ctttggagcc aagcaagctc ttcgagatgt cttgaaacgc tttggtgtgc cagagtatga
    27121 attatctgca attactaaga aaatcagttt tcgtgacaat cttaagtcgg cctatgaggg
    27181 caatctccag tttcgtcagc aaatcaatag taagttagaa taccaaaaag cttttgagat
    27241 tgcttgcaag atagagggct atccaaggca aacctctgtc catgcggctg gtgttgtaat
    27301 tagtgaccaa gatttaacca actatattcc tctaaagtat ggtgatgaaa ttccactgac
    27361 tcagtatgat gctcatggag ttgaggctag cggacttttg aagatggact ttctgggact
    27421 acgaaatttg acctttgtcc agaagatgca agagttgctt gctgaaatag aaggtattca
    27481 ccttaaaatt gaagaaatag atttggaaga caaagaaacg ttagatttat ttgcctctgg
    27541 aaatacaaaa ggtatctttc aatttgagca accaggtgcc attcgtctgc ttaagcgtgt
    27601 gcaaccagtc tgttttgaag atgtcgtcgc gactacttct ctaaatcgac cgggtgctag
    27661 tgactatatc aataattttg tggcaagaaa gcatgggcag gaagaagtga ctgttctgga
    27721 tccagtactg gaggatattt tggctccaac ctacggcata atgctctatc aggagcaggt
    27781 tatgcaggtt gcccagcgac ttgccggatt tagtcttggg aaagccgata ttttgcgtcg
    27841 ggctatgggg aaaaaggatg cctctgccat gcatgagatg agggcttcct ttattcaagg
    27901 ttcattagaa gctggtcata ctgtggaaaa agcagagcag gtctttgatg ttatggagaa
    27961 gtttgcaggt tatggtttta acaggtcaca cgcctatgcc tactcagcct tggccttcca
    28021 gttggcttat ttcaaaacgc attatccagc cattttttat caggtcatgt taaattcttc
    28081 caacagtgat tacttaatag atgcacttga agcaggtttt gaagtagcct ctctatccat
    28141 caacaccatt ccctatcacg ataaaattgc caacaaggcc atctatctag gtttgaaatc
    28201 cattaaagga gtcagtaatg atttagctct ctggattatt gaaaatagac cttattctaa
    28261 cattgaagat tttatagcta aattacctga gaattatctg aaacttcctc tgctagaacc
    28321 tttggtaaaa gttggtcttt tcgattcatt tgaaaaaaat cgtcaaaaag tatttaataa
    28381 cttagctaat ctatttgaat ttgtgaaaga gttgggaagt ttgtttggag atgctattta
    28441 tagttggcag gaatcggaag attggacgga acaagaaaaa ttttatatgg aacaagagct
    28501 tttagggata ggtgtcagca aacatccact acaagctatt gcaagtaagg ctatttaccc
    28561 gattacccca attggaaatt tgtcagaaaa tagctatgct attatcttgg ttgaagttca
    28621 gaagataaaa gtaattcgta ccaaaaaggg tgaaaatatg gctttcttac aggtggatga
    28681 cagtaagaaa aaattggatg ttacactctt ctcagattta tatcgacagg ttgatcagga
    28741 agtaagagaa ggagcattct actatatcaa agggaaagtc cagtcacgtg acggtcgtct
    28801 gcaaatgatt gcacaagaaa taagagaagc agtggctgag cgcttttgga ttcaggttaa
    28861 aaatcatgac tcggatcaag agatgtcacg tattttagac cagtataaag gcccaatccc
    28921 agtcatcatc cggtatgaag aggaacagaa aaccatcgtt tctccccatc attttgtagc
    28981 taaatctgat gaattagagg cgaaattgaa tggaatagtt atgaaaacga tttatcgcta
    29041 aaaatacgga aaatagaaga attttaaaat caaatgtgat ataatcaaga agaatgttaa
    29101 aagaaaaagg agcataaacc aatatgaaac gtattgctgt tttgactagt ggtggagacg
    29161 cacctggtat gaacgctgct atccgtgcag ttgttcgtca agcaatttca gaaggaatgg
    29221 aagtgtttgg tatctatgac ggatatgctg gtatggttgc cggtgaaatt caccccctag
    29281 atgcagcttc agtaggagac atcatttctc gtggtggtac ttttcttcac tcagctcgtt
    29341 atccagagtt cgctcaactt gaagggcaac ttaaagggat tgagcaattg aaaaaacacg
    29401 gaattgaagg tgtagttgtt atcggtggtg acggatctta ccacggcgct atgcgtttga
    29461 ctgaacatgg cttcccagct attggtcttc caggtacaat cgataacgat atcgttggta
    29521 ctgactttac aatcggtttt gacacagcgg ttactactgc catggacgct atcgataaga
    29581 ttcgtgatac atcatcaagt caccgtcgta cttttgtaat cgaagttatg ggacgtaacg
    29641 ctggtgatat cgctctttgg gctggtattg caactggtgc tgatgaaatc atcatccctg
    29701 aagcaggctt caagatggaa gatatcgtag caagcatcaa agctggttat gaatgtggta
    29761 aaaaacacaa tatcatcgtc ttagctgaag gtgtgatgtc agcggctgaa tttggtcaaa
    29821 aacttaaaga agctggagat acaagcgacc ttcgtgtaac agaacttgga catattcaac
    29881 gtggtggttc tccaactgcg cgtgaccgtg ttttggcgtc acgtatgggt gcacatgctg
    29941 ttaaacttct taaagaaggt atcggtggtg ttgcggttgg tattcgtaac gaaaaaatgg
    30001 ttgaaaatcc aattcttggt actgcagaag aaggggcatt gtttagcctt actgcagaag
    30061 gtaagattgt ggttaacaac ccacacaaag ccgatattga gctatctagc ttgaataaga
    30121 gcttgtcata atttacaatt tagttaataa gaccaaaaag gtcatatata taaaggagtc
    30181 acaaaaatca tgaacaaacg tgtaaagatc gttgcaactt tgggtcctgc ggtagaaatc
    30241 cgtggtggta aaaaattcgg tgaggatgga tactggggtg aaaaacttga tgttgaagct
    30301 tcagctaaaa acattgctaa attgattgaa gctggtgcta acacattccg attcaacttc
    30361 tcacacggcg accaccaaga acaaggtgag cgtatggcaa ctgttaaact tgcggaaaaa
    30421 attgcaggta aaaaagttgg tttccttctt gatacaaaag gacctgaaat ccgtacagaa
    30481 ttgttcgaag gtgaagctaa agaatattca tacaaaactg gtgaaaaaat tcgtgttgca
    30541 actaaacaag gaatcaaatc aactcgtgaa gtgattgcgt tgaacgttgc tggtgctctt
    30601 gatatctatg atgatgttga agttggtcgt caagttttgg ttgacgatgg taaacttggt
    30661 cttcgtgtgg ttgctaaaga tgatgcaact cgtgaatttg aagttgaagt tgaaaacgat
    30721 ggtatcatcg ctaaacaaaa aggtgtgaac atccctaaca ctaaaattcc tttcccagct
    30781 cttgctgaac gcgataacga cgatatccgt ttcggtcttg aacaaggtat caacttcatc
    30841 gcaatttcat tcgtacgtac tgcaaaagat gtgaacgaag ttcgtgcaat ctgtgaagaa
    30901 actggaaacg gacatgttca attgttcgct aaaatcgaaa accaacaagg tatcgataac
    30961 ttagacgaaa tcatcgaagc agctgatggt attatgattg ctcgtggtga tatgggtatc
    31021 gaagtaccgt tcgaaatggt tccagtttat caaaaaatga ttatcaagaa agtcaatgct
    31081 gcaggtaaag ttgttatcac tgcaacaaac atgcttgaaa caatgactga aaaaccacgt
    31141 gcaactcgtt cagaagtatc agacgtattc aacgctgtta tcgacggaac tgacgctaca
    31201 atgctgtcag gcgagtctgc aaacggtaaa tacccactcg agtcagtaac tacaatggct
    31261 acaatcgaca agaacgctca agctcttctt aatgaatacg gacgtcttga ttcagattca
    31321 tttgagcgta actctaagac agaagtaatg gcttctgctg ttaaagatgc tactagctca
    31381 atggatatca aattggttgt aactcttact aagacaggtc atactgcacg tttgatttct
    31441 aaataccgtc caaatgctga catcttagca ttgacatttg acgaattgac agaacgtggc
    31501 ttgatgttga actggggtgt tattccaatg ttgacagatg ctccatcttc aactgacgat
    31561 atgttcgaaa tcgctgaacg taaagcggta gaagcaggtc tcgttgagtc aggcgatgat
    31621 atcgttatcg ttgctggtgt gccagtagga gaagctgttc gcacaaacac aatgcgtatc
    31681 cgcacagtac gttaagaaaa atataaaaac ctatcatatc cagctttaga gcttgtgtga
    31741 taggcttttt gtatagaggg taagaaatag gcaaaacttt cataatggat t
//
LOCUS       DBERAE010000024        31745 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.24, whole genome shotgun sequence.
ACCESSION   DBERAE010000024 DBERAE010000000
VERSION     DBERAE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.24"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            500..1543
                     /locus_tag="ACL70N_001265"
     CDS             500..1543
                     /locus_tag="ACL70N_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGS0590062.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1710..3797
                     /gene="topA"
                     /locus_tag="ACL70N_001266"
     CDS             1710..3797
                     /gene="topA"
                     /locus_tag="ACL70N_001266"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGS0590063.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3903..4262
                     /locus_tag="ACL70N_001267"
     CDS             3903..4262
                     /locus_tag="ACL70N_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGS0590064.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4355..4987
                     /locus_tag="ACL70N_001268"
     CDS             4355..4987
                     /locus_tag="ACL70N_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGS0590065.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5031..5687
                     /locus_tag="ACL70N_001269"
     CDS             5031..5687
                     /locus_tag="ACL70N_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGS0590066.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5757..6800
                     /locus_tag="ACL70N_001270"
                     /pseudo
     CDS             5757..6800
                     /locus_tag="ACL70N_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            6812..7838
                     /gene="leuB"
                     /locus_tag="ACL70N_001271"
                     /pseudo
     CDS             6812..7838
                     /gene="leuB"
                     /locus_tag="ACL70N_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7835..8104
                     /locus_tag="ACL70N_001272"
     CDS             7835..8104
                     /locus_tag="ACL70N_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGS0590067.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8108..8467
                     /gene="leuD"
                     /locus_tag="ACL70N_001273"
     CDS             8108..8467
                     /gene="leuD"
                     /locus_tag="ACL70N_001273"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGS0590068.1"
                     /translation="MVGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8629..9252
                     /locus_tag="ACL70N_001274"
                     /pseudo
     CDS             8629..9252
                     /locus_tag="ACL70N_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            9418..11349
                     /locus_tag="ACL70N_001275"
     CDS             9418..11349
                     /locus_tag="ACL70N_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGS0590069.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11336..12652
                     /locus_tag="ACL70N_001276"
     CDS             11336..12652
                     /locus_tag="ACL70N_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGS0590070.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12827..13813
                     /locus_tag="ACL70N_001277"
     CDS             12827..13813
                     /locus_tag="ACL70N_001277"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGS0590071.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13877..13948
                     /locus_tag="ACL70N_001278"
     tRNA            13877..13948
                     /locus_tag="ACL70N_001278"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13910..13912,aa:Arg,seq:ccg)
     gene            14131..14829
                     /gene="rnc"
                     /locus_tag="ACL70N_001279"
     CDS             14131..14829
                     /gene="rnc"
                     /locus_tag="ACL70N_001279"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGS0590072.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14820..18359
                     /gene="smc"
                     /locus_tag="ACL70N_001280"
     CDS             14820..18359
                     /gene="smc"
                     /locus_tag="ACL70N_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGS0590073.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENACKFLDL
                     EGQRKAIYLDVLVAQIKENKAEIESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIVIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18356..19150
                     /locus_tag="ACL70N_001281"
     CDS             18356..19150
                     /locus_tag="ACL70N_001281"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0590074.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19150..19968
                     /locus_tag="ACL70N_001282"
     CDS             19150..19968
                     /locus_tag="ACL70N_001282"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0590075.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVSEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19972..21249
                     /gene="ftsY"
                     /locus_tag="ACL70N_001283"
     CDS             19972..21249
                     /gene="ftsY"
                     /locus_tag="ACL70N_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGS0590076.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21293..22780)
                     /gene="zwf"
                     /locus_tag="ACL70N_001284"
     CDS             complement(21293..22780)
                     /gene="zwf"
                     /locus_tag="ACL70N_001284"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGS0590077.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(22929..23669)
                     /locus_tag="ACL70N_001285"
     CDS             complement(22929..23669)
                     /locus_tag="ACL70N_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0590078.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23669..25834)
                     /locus_tag="ACL70N_001286"
     CDS             complement(23669..25834)
                     /locus_tag="ACL70N_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS0590079.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            26007..26960
                     /locus_tag="ACL70N_001287"
     CDS             26007..26960
                     /locus_tag="ACL70N_001287"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGS0590080.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27037..29025
                     /gene="uvrB"
                     /locus_tag="ACL70N_001288"
     CDS             27037..29025
                     /gene="uvrB"
                     /locus_tag="ACL70N_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGS0590081.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29035..29598
                     /locus_tag="ACL70N_001289"
     CDS             29035..29598
                     /locus_tag="ACL70N_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0590082.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            29564..30073
                     /locus_tag="ACL70N_001290"
     CDS             29564..30073
                     /locus_tag="ACL70N_001290"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0590083.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            30126..30593
                     /locus_tag="ACL70N_001291"
     CDS             30126..30593
                     /locus_tag="ACL70N_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS0590084.1"
                     /translation="MSRSQLTILTNICLIEDLETQCVVMQYRAPETNRWSGYAFPGGH
                     VENGEAFAESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYKATEFTGTLQS
                     SDEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30590..31105)
                     /locus_tag="ACL70N_001292"
     CDS             complement(30590..31105)
                     /locus_tag="ACL70N_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGS0590085.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHQVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31117..31644)
                     /locus_tag="ACL70N_001293"
     CDS             complement(31117..31644)
                     /locus_tag="ACL70N_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0590086.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT         9850 a         5618 c         7047 g         9230 t
ORIGIN      
        1 tattttagca gccaaggtgc actgttatag attcaataca ctataattta gtgtaattga
       61 gaaaggagaa atgattgtga ttgatgttgg ctaggttatg ttcaatgatt cctaccgtct
      121 caaatcttgt cagtaaggaa aaataaattc ttcaaaagta gagattacaa ggcttgttta
      181 agaaagaatt caaagacctt gacaaataaa aataaaatgg ttattataag aaatggtcta
      241 aaatagatga tgatactttt cgaaaatctt tttacgtcag ctcagctttg ccttgctgtg
      301 ttttgagcaa gctacggtta gcttccgagt ttgattttca tttactagaa atgaaactga
      361 tgagagatat cagtagacat ttgagtcagg atattatgga aaatgataaa aagagctcgt
      421 gagattggca tatcagacta ctaaagtatt gagtttgtta ggattttagc gactagttag
      481 ctgggaaagg aagatatttg tgacaaataa taaactgtat tcgttgatag aatttagaaa
      541 taaaatatat gaagaattag aactttccag aagtgattta gcgattttac tatgtgccat
      601 gcttatcgcc tctatcggat taaatatgga ttcgactccc gtgattattg gagccatgtt
      661 aatctctcct ttgatgacac ctattctggg agtggggctc tctctagcta tatttgattt
      721 taaattgtta agaaaatctt ttaaaatatt agctattcaa attcttgcca gtctaatagc
      781 ttcaacactt tatttttatc tttctcccat ttcgtatgct agttcggaga ttgttgctag
      841 aacctctccg actatttggg atgttctcat tgcttttgta ggagggatag caggtattat
      901 tggtgctagg aaaaaagaga ccaataatat tgttcctggt gttgctattg caaccgcctt
      961 gatgcctcct ctttgtacag taggttatgc tattgcttct gctaatctaa aatttatcat
     1021 aggctcctct tacctattcc tcatcaattg tagctttatt gtcattgcga cttatatagg
     1081 tgttaggttg atgatggtta agaaacatta ttttaaagat aacgaagaag actctaaaat
     1141 gcgtaggatt ttgcttctag ttgctgtttt gctgatgatt ccgagtttca tctctgcaac
     1201 gactttagtg agagaaacgt tgaaaaaaga gtcccttaag aaatttatat cagagcagtt
     1261 tcaggggtat aatattttga aaaaaaccta ttctaaaaag actcataccc taaagctaac
     1321 catttcagga aattatttga cagaagaaga actcgatatg atttcaagta agagaggtga
     1381 ctatggttta agtgatgttt ctgttcaagt ttcacaattg tctgattcag aacaacttag
     1441 taaggaagag ctggtggagt atttcttcca gtatatcaag gataaggaag caaaagaaaa
     1501 ggagaaagcc aataaatttg atacagagtc tgaggagcaa taatttcttg agaatagctg
     1561 gtttctctcg tgagtcttct atgtatatca aaggaagact gaggttttaa gtataaaact
     1621 tttcttctat tatagtagct aagtcttgac agggttcaaa aaatggttta cactttataa
     1681 agtttattac tttgaaaagg tgtgatactg tggctacggc aacaaaaaag aaaaaatcaa
     1741 cagttaaaaa aaatctagtc atcgtggagt cgcctgctaa ggccaagacg attgaaaaat
     1801 atctaggcag aaactacaag gttttagcca gtgtcgggca tatccgtgat ttgaagaaat
     1861 ccagtatgtc cgtcgatatt gaaaataatt atgaaccgca atatatcaat atccgaggaa
     1921 aaggccctct tatcaatgac ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg
     1981 cgagtgaccc ggaccgtgaa ggagaagcga tttcttggca tttggcccat attctcaact
     2041 tggatgaaaa tgatgccaac cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa
     2101 atgcttttaa agaacctcgt aagatcgata tggacttggt cgatgcccaa caagctcgtc
     2161 ggatcttgga tcgcttggta gggtattcga tttcgcctat tttgtggaag aaggtcaaga
     2221 agggcttgtc agcaggtcgc gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa
     2281 atgaaatcaa tgccttccag ccagaagaat actggacagt tgatgctgtc tttaaaaagg
     2341 gaaccaaaca atttcatgct tccttctatg gagtagatgg taaaaagatg aaactgacca
     2401 gcaataacga agtcaaggaa gtcttgtctc gtctgacgag taaagacttt tcagtagatc
     2461 aggtggataa gaaagagcgt aagcgcaatg ctcctttacc ctataccact tcatctatgc
     2521 agatggatgc tgccaataaa atcaatttcc gtactcgaaa aaccatgatg gttgcccaac
     2581 agctctatga aggaattaat atcggttctg gtgttcaagg tttgattacc tatatgcgta
     2641 ccgattcgac tcgtatcagt cctgtagcgc aaaatgaggc ggcaagcttc attacggatc
     2701 gttttggtag caagtattct aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg
     2761 atgcccatga ggctattcgt ccgtcgagtg tctttaatac accagaaagc atcgctaagt
     2821 atctggacaa ggatcagctc aagctatata cccttatctg gaatcgtttt gtggctagcc
     2881 agatgacagc ggccgttttt gataccatgg ctgttaaatt gtctcaaaat ggagttcaat
     2941 ttgctgccaa tggtagtcag gttaagtttg atggttatct tgccatttat aatgattctg
     3001 acaagaataa aatgctacca gatatggctg ttggagatgt ggtcaaacag gttaatagca
     3061 aaccagagca acatttcacc caaccgcctg cccgttattc tgaagcaaca ctgattaaaa
     3121 ccttagagga aaatggggtt ggacgtccat caacctatgc gccaaccatt gaaaccattc
     3181 agaaacgtta ttatgttcgc ctggcagcca aacgttttga accgacagag ttgggagaaa
     3241 ttgtcaataa gctcatcgtt gaatatttcc cagatatcgt aaacgtgacc ttcacagctg
     3301 aaatggaagg taaactggat gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg
     3361 atgcctttta caaaccattc tctaaagaag ttgccaaggc tgaagaagaa atggaaaaaa
     3421 tccagattaa ggatgaacca gctggatttg actgtgaagt gtgtggcagt ccaatggtca
     3481 ttaaacttgg tcgttttggt aaattctacg cttgtagcaa tttcccagat tgccgtcata
     3541 cccaagcaat cgtgaaagag attggtgttg agtgtccaag ctgtcatcag ggacaaatta
     3601 ttgagcgaaa aaccaagcgt aatcgccttt tctatggttg caatcgctat ccagaatgtg
     3661 aatttacctc ttgggacaag cctgttggtc gtgactgtcc aaaatgtggc aacttcctca
     3721 tggagaaaaa agtccgtggt ggtggcaagc aggttgtttg tagcaaaggc gactacgagg
     3781 aagaaaagat taaataagag gaggggcccg aaagtaaatt tcaggctcct tttggttaga
     3841 acttgacaaa atacatcatt ttatgcgaaa ctagaagaag attattttaa ctaggagaag
     3901 ttatgcgtct tatctatctg ataattggtt ttttatcact ggccttggct attgttgggg
     3961 ttgttttacc cttgttgccg acaacgcctt tccttttgtt gtctattgct tgtttctcca
     4021 gaagttccaa gcgtttcgaa gactggcttt atcataccaa gctctatcaa acatatgtag
     4081 ctgattttcg cgagactaag tctattacgc gtgaacgaaa gaaaaaaatc atcgtctcta
     4141 tctacgtctt gatgggaatt tctatttatt ttgcacctct tttaccagtc aaaatcggtc
     4201 tgggtgcttt gaccatcttt atcacttatt atcttttcaa ggtcattcca gacaaagaat
     4261 agttaaaaca gtagttattt gccttgataa aattgaaagc atattcataa taatatgata
     4321 taataaattt gaagtaatat tcaaggagaa tcaaatgatt tacgaatttt gtgctgaaaa
     4381 tgtgacttta cttgaaaaag cgatgcaggc tggagctcgt cggattgaac tctgtgataa
     4441 tctagcagtt ggtgggacaa cacccagcta tggagtgact aaggcagcgg ttgaactggc
     4501 agctaactac gatacaacca tcatgaccat gattcggcca cgtggtggtg actttgtcta
     4561 taatgaccta gaaattgcta tcatgctaga agacattcgt ttgactgctc aggctggaag
     4621 tcaaggggtt gtatttggaa ctttaactgc tgataaaaag ttggataagc ctaatctgga
     4681 aaagttaatt gctgcatcaa aaggaatgga aattgtcttt cacatggcct ttgatgaact
     4741 aagtgatgaa gatcaaccgg aagctattga ctggctcagt caagccggtg tcactcgtat
     4801 cctaactcgt gctggtgtgt ctggcgactc cttagaaaaa cgttttgttc actatcacag
     4861 aattttggag tacgctaaag gtaaaattga aattctacca ggtgggggga ttgaccttga
     4921 aaaccgtcaa acctttatcg accaggtggg ggtaacacaa ttgcatggta ctaaggttgt
     4981 tttttaaaaa atagaaagga actgctagct ttgggtagca gttttcactt atgtttgaaa
     5041 tttttaaatc ctatcaattt aatcaagaaa aggctcatga ttatggtttt atagaaaata
     5101 gcgaagtctg gacatatagt tgccagattt tgcaaggtga ctttgtcatg actgtgtcca
     5161 tcactgctga taatgtgaac tttcaagtct ttgaccaaga gactggtgac ctctatcctc
     5221 acgttcatat ggaaagcatg aggggaagtt ttgtcggaaa tgtccgtgag gcttgtctgg
     5281 agattcttta ccagattcgg aaggcttgtt ttgatgtgca agattttatc tgtcatcaga
     5341 ctaagcgtat catgactcaa gttcaggaaa agtatggaaa ccagttggag tatctgtggg
     5401 aaaaatcgcc tgatacagct gtattgcgcc atgaaggcaa tcaaaagtgg tatgccgtct
     5461 tgatgaaaat ctcttggaat aagctggaaa agggcagaga aggacaagtg gaagcagtca
     5521 acctcaagca tgaccaagta gctaatttgc tttcacaaaa ggggatttat ccagccttcc
     5581 atatgagcaa gcgctactgg attagtgtgt cccttgatga tactttatca gatgaagaag
     5641 tactggaatt gatagaaaaa agttggaact taacctctaa aaaatgaaat attttaataa
     5701 ttttcatgaa ctttcaatta gctaaatatt ctttactgaa gaaattttca gaaaatatag
     5761 gatttaccac accagaggaa tatggtgcca tcttcaaata cctgattgag aatgtcaaga
     5821 cggatcgtca gatcatctat tcgcctcact gtcatgatga cctcggaata gcagtggcaa
     5881 atagccttgc tgctgtcaag aatggtgcag gacgtgttga agagactatc aatggtatta
     5941 gggagcgagc tggaaatgct gctttggaag aaattgcagt ggctctcaat attcgccaag
     6001 attactacca agtagaaacc agtattgtcc taactgagac catcaatacg tcagaaatgg
     6061 tttctcgctt ctctggtatt ccagttccta aaaacaaagc cgtcgttggt ggcaatacct
     6121 tctcccacga atctggtatt caccaagatg gagtccttaa aaatcctctc acttatgaga
     6181 tcatcacacc tgaattggtt ggtgttaaga ttccgcttgg aaaattatct ggtcgccatg
     6241 cttttgttga gaaactgaga gaattggccc tagattttac agaagaggat atcaaaccac
     6301 tctttgctaa gttcaaggca ctggtcgata agaagcaaga aatcacagat gcagatattc
     6361 gagctttggt agctggaacc atggttgaaa atccagaagg cttccacttt gatgatttac
     6421 aacttcaaac tcatgcagat aatgacattg aagcgctcgt tagcctagcc aatatggatg
     6481 gtgagaaagt cgaatttaat gcgacagggc aaggttccgt tgaagcaatc tttaatgcta
     6541 tcgataagtt ctttaaccaa tctgttcgtt tggtgtccta cactatcgat gcggtaacag
     6601 atggaatcga tacccaggaa cgggttttgg tcactgttga aaacagagat acagaaacca
     6661 tcttgaatgc agcagggctt gattttgatg tgttgaaggc ttctgctatt gcctatataa
     6721 acgctaatac ctttgttcaa aaagagaatg caggtgagat gggacgcagt gtttcttacc
     6781 acgatatgcc tagtgtgtaa aggagaaggc tatggcaaag aaaatagtag ctctagcagg
     6841 agacggaatt ggcccagaaa tcatggaggc tggtttagaa gttctggagg ctctagctga
     6901 aaaaacaggt tttgactatg agatcgttcg gaggtgcaga tattgatgca gcaggatctc
     6961 ccttacctga tgaaaccctt aaggcaagta gggaagcaga tgctatccta ctagtagcta
     7021 tcggtagtcc tcagtatgat ggagtagcgg ttcgccctga acaaggcctg atggctctcc
     7081 gtaaggaact caatctttac gctaatattc gtcctgtaaa aatctttgac agtctcaagt
     7141 atttgtcacc actcaaaccg gaacgaattt ctggtgtaga ctttgtcgtg gtgcgtgaat
     7201 tgacaggcga gatttacttt ggagatcata ttcttgaaga gcgcaaagcg cgtgatatca
     7261 acgactatag ctatgaggaa gtggagcgga ttattcgcaa agcctttgaa attgcaagaa
     7321 atcgcagaaa aatcgttact agtatcgata agcaaaatgt tctagcgacc tcaaaactct
     7381 ggcggaaagt agctgaggaa gtcgcacagg atttcccaga tgtaaccttg gaacaccagc
     7441 tggtagactc agctgctatg cttatgatta ccaatcctgc taagtttgat gttattgtaa
     7501 cggagaatct ttttggagat attttatctg atgaatcaag cgtcttatct ggtacacttg
     7561 aggttatgcc atcagccagt cattctgaaa atggaccaag tctctatgaa cctattcacg
     7621 gttcagcacc tgatattgca ggtcaaggaa ttgccaatcc tatttccatg attttattag
     7681 ttgtcatgat gttgagagat agtttcggac gttatgagga tacagagcgt atcaaacgtg
     7741 ctgttgagac aagtctggcg gcaggaattt taacgagaga tataggaggt caggcttcaa
     7801 caaaggaaat gatggaagct attattgcaa ggttatgaag ttagacgaaa aaattactct
     7861 agtccttttg atttggaatg tcatcatttt cttgatttat ggcattgaca aattcaaggc
     7921 aagaagaaga gcttggcgca tcccagagaa aatcttactc attttagccc ttacttgtgg
     7981 tggttttggg gcctggttag ctggaatcac ttttcaccac aagactcgaa aatggtactt
     8041 taaaacagtt tggtttcttg ggatggtgac cacactagta gccttatatt ttatttggag
     8101 gtaatggatg gtagggtctt cgagggaaca cgctgcttgg gctctagcgg actatggttt
     8161 taaggtcgtg attgcaggat ctttcggtga cattcattac aataatgaac tcaataatgg
     8221 catgttgcca atcgttcagc ctagagaggt tagagagaaa ctagcccagc taaaaccaac
     8281 cgaccaggta actgtggact tggaacaaca aaaaatcatc tcaccagttg aagaattcac
     8341 cttcgagata gatagcaagt ggaaacataa actcctaaat agtttggatg atatcggtat
     8401 taccttgcag tatgaagagt tgattgctgc ttatgaaaaa caacgaccag cctactggca
     8461 ggattagaaa aaatagaaaa ggaaatatag taaactgaaa taagatgtaa acaaatgaat
     8521 tggagcttaa catccatttc cagcaatttt ttagaaacta cagtggacta ttctggattc
     8581 aacacattat aaaattatga caaaacacat tcacaagaag gctacgacat tttaaaaggt
     8641 gagggcggat gtatcgtttg ccctactaaa gttggttaca ttatcatgac cagcaacaag
     8701 gcaggacttg agcgtaagtt cgcagccaaa gaacgtaagc gtaacaaacc aggtgttgtt
     8761 ctctgcggta gcatggatga acttcgcgct ttagcgcaac tcaacccaga aattgaagca
     8821 ttctactaaa aacattggat gaagatattc ttcttggttg tatccttcct tggaaaccag
     8881 aagcctttga aaaactcaaa gcatacgggg atggccgtga agaacttatg actgatgtac
     8941 gtggtactag ctgttttgtt atcaagtttg gaaaagcagg tgaacaattg gctgccaagc
     9001 tttgggaaga aggtaaaatg gtctacgcct catatgcttc aatgacaaaa cgattgaaac
     9061 tcgctatgag agcaaggtgt aatggtgtct atggtcgata aggacggcaa actcatccca
     9121 gaacaaggag gagcacgttc aacttcacca gcaccagttg tgatccgtaa agggcttgac
     9181 attgataaaa tcatgatgca cctgtcagat acttttaact catgggacta ctgtcaggtt
     9241 gagtattatt aagataaaaa aagaagtcta gtgttatgag atattaaagc tcctaacact
     9301 ggactttttg tttagaattt cttttctttt tctataggat atggtattct atgtagaaaa
     9361 tatatgttaa taagtaatgc caatatttaa acatcattag taaaaggagt tagattgatg
     9421 aataaaagaa aagttagttt agaagatttt tataaatggt atagtctaaa taaagaagag
     9481 ttattaaata aggcaactgt tggtgaaaag tttaatgata aattaaaaga agagtttctc
     9541 caggaatggc ctttggatag gattttaaca atgtcaatcg atgaatatgt aataggaaag
     9601 ggacagcaaa ataagtcttt atgctacgct cttgagaagg gaaaatacaa aaatctattt
     9661 cttggaattt ctggtggctc agcttcaaaa tttggtattt attggaataa aaaaacaaac
     9721 aaatataaag atcaagctaa taatgagatt tcagagttgg atcagcgatt ttcaaaatta
     9781 aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt ttaactttga aaatcctatt
     9841 tttgatatga aaagatcaac aaatgaattt attggtcgtt ctgctatggt gacaaaatta
     9901 ctttgtatct atactgaggg agatcctttc tttggtgtaa atattaatag tcagaaagaa
     9961 ttttggaacc actttgtttc tcagacaaat caaggtggac cttatctgca aaatcataaa
    10021 ataattgaac tggtgtccaa aacttatcct gagttggagc catcgaaatt aggaactatg
    10081 ctttttgagt attctaagct ttttatggaa aataaggaag acaatagtac aatggattca
    10141 tcaaacaatt ttagtcatca attaactcaa tctctattaa agtctccaaa ccttatcctt
    10201 cgtggtgctc ctggcacagg aaagacttat cttgctaaag aaattgccaa agaattaacg
    10261 gatggcaacg aagaccaaat cggatttgta caatttcacc catcctatga ttatacggat
    10321 tttgtagaag gtttaagacc agtatcaaat ggggatggag ctattgagtt taggctacag
    10381 gacggtattt ttaaagattt ttgtcagaaa gcaaaagaaa cccaattgat tggaggacaa
    10441 gataattttg atgaggcttg ggattcttac ttagaatata taaatgttgc tgaagaaaaa
    10501 gaatatataa caaaaacatc ttacttatct gttaatagta gacaaaattt gtcagtaaat
    10561 tatgatagtg gtgttccagg atggtcacta cctagcaaat atgtttacga gttgtataaa
    10621 gataaaaatt ataataagca agaatactac aaaagtggtg gaaaaactgt cctagaaaca
    10681 ttgagaaaga gatttggttt gaaagactat gtttccccaa cagaaattga tactgataag
    10741 aaattcgtct tcatcatcga tgaaatcaat cgtggggaga tttctaagat ttttggcgaa
    10801 ctctttttct ctatcgaccc tggctatcgt ggtgaaaaag gaagtgtttc tacccaatat
    10861 gcaaatctac acgaaactga tgaaaagttc tatatccccg aaaatgttta catcatcgga
    10921 actatgaatg atattgatcg ttcagtggat acctttgatt ttgctatgcg tcgtcgtttt
    10981 cgttttgttg aagttactgc cgagggtcaa gttggcatgt tggataaaga gctgaatatc
    11041 catgcagaag aagcaaaaat tcgtctaaga aacttgaacg ctgctatcga aaatgttcag
    11101 gaattaaaca gtcattatca tattggacca agttattttc ttaagttgaa ggatgtagat
    11161 tttgactatg aattactctg gtctgattat attaagcctc tcctagaaga ctacttgcga
    11221 ggttcttatg atgaggttga aactttggaa actttgaaaa aagcatttga actgacaaat
    11281 aatgagcaaa aagatcaggc agtagctgat gacaatgaag gcgatgaaaa cgatgatgcg
    11341 gattactgat aatcaacaca agattattaa agaaaaattt gttgaagaat atcctaaact
    11401 aagcaatctt cttttagaca gaaccttgga aagtctatcc caagatgaac gtattttcat
    11461 ttttccaaat gatttgactc atactcctga tttggataag gaccaaaaga tttttgaaac
    11521 agtcaatcag aaaatcaaga cagggaacgt gattggtttt cttggatatg gtcaggaaag
    11581 attaacgatt tcctcacgat tttctgatga gagtaatgac cattttttgc attatctctt
    11641 aaacaaggtt cttcatatca atctcactag tttagatgtt gctttgtctc gtgaagagag
    11701 gctttatcaa cttttgatgt atctcttccc caagtatcta caagctgcta ttcgaaaagg
    11761 tctttataag gaataccaga gattttctca taacgacagt catgttaagg gagtgattga
    11821 tgtaagaaac catctcaaga aaaatcttcc tttcacggga aatattgcct acgcaacgag
    11881 agagttcacc tatgataatc ccctcatgca gttggtccgt cacactattg aatacattaa
    11941 gaatcagaaa agcattggtc aaggggtact agataatctc tcaactagtc gtgaaaacgt
    12001 atctgaaatc gtgcgtgtaa cgccctctta taaactagct gatcgtgcta agattattcg
    12061 gggaaatcaa tctaaaccta tacgtcatgc atactttcac gagtacagaa acttacaaga
    12121 actttgtctg atgatcctaa accaagaaaa gcacggttta gggtatcaag atcaaaaaat
    12181 ctatggtatt ctctttgatg ttgcctggct ttgggaagag tatgtttaca ccttgttgcc
    12241 aaaaggtttt gtacatccca gaaataagga taagacggat ggaatttcag tattttctgt
    12301 tgggaaacga aaagtatatc cagattttta tgacagagaa cgaaagattg ttctagatgc
    12361 aaaatataaa aaactggaat tgactgaaaa aggaatcaac cgtgaggact tattccagct
    12421 gatttcctat tcttatattt taaaagctga gaaggctgga ctgatttttc ctagtatgga
    12481 gcagtcagta aatagtgaaa taggaaaagt agctggctat ggagctcaat tgaagaagtg
    12541 gtctattcga atccctcaga atgcctcatt ctatagtaca ttttgtaaaa tgatggaaaa
    12601 ttcagaagaa aattttaaag cgattattga tgaagaagtg gggagaaaat aatttcccct
    12661 ctttctttta tttttaacac aagtaaaacc cgaacgatat attttaattc ataaaataat
    12721 ttgacaaaaa ctgtactttg atttataata aattaaggaa acgtcggaaa aggcgtagtg
    12781 atgcaagagc ataggtaggt cattacaaaa gaaacgagac atcgatatgt taaatgaatt
    12841 tccaattttt gattacgaag atattcaatt gattccaaat aaatgtgtca ttaaaagccg
    12901 tgcagaagcg gatacaagtg tcactttagg aaatcacacc tttaaactac ctgttgtgcc
    12961 agcgaatatg cagacgattt tggatgaaaa tgtagcagag caactggcta aaggtggtta
    13021 cttctacatt atgcaccgtt ttgatgaggc aggacgcatt ccttttatta aacgaatgca
    13081 caatcaaggg ctcattgctt ctatctctgt cggtgttaag gattatgagt atgattttgt
    13141 tagccagctc aaggctgata ctcctgagta tatcactatt gatattgctc atggtcatgc
    13201 ggatagcgtg atttctatga ttcaacacat caagaaagaa ttgccagata cctttgtcat
    13261 tgctggaaat gtgggaacac cagaagctgt gcgtgaattg gaaaatgctg gtgcggatgc
    13321 tactaaggtc ggaatcggtc ctggtaaggt ttgtatcacc aaggttaaga ctggttttgg
    13381 tacaggtggt tggcagttgg ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat
    13441 tatcgctgat ggaggaattc gtactcacgg tgatattgcc aagtctatcc gcttcggtgc
    13501 tagcatgatc atgattggtt ccctctttgc aggacacatt gaaagtccag ggaaaacgat
    13561 tgaagtcgat ggtgaacagt tcaaagaata ttatggttca gcctcacaat atcaaaaagg
    13621 tgcttacaaa aatgtggaag gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga
    13681 cactttaact gagatggaac aagaccttca aagtgctatt tcttatgcag gtggacgtca
    13741 ggttgctgac cttaaacacg ttgattatgt gatcgtgaaa aactccatct ggaatgggga
    13801 tgcttcccac taagacgggg tctttgacca aaaaacttgt tattagagca aatttctgtt
    13861 ataataaaac aagtttccac ccttagtgta atggatatca cgtaagattc cggttcttga
    13921 gatgggggtt cgattccctc agggtggatg taaacatcct aaaaagcctt taatagggct
    13981 tttttcttta tcctgaccca aatttgccgc taaaactgag aatctctgtc taaagaattc
    14041 ccaaatgctt tccagtcccg ttttagagtg actcaggggg ctttttttga tataataaaa
    14101 aggactatta tcagttagaa agaggttggt atgaaagaat tacaaactgt actaaagaat
    14161 cattttgcaa tcgaatttgc agacaaaaat ttactggaaa ctgcctttac tcatacgagt
    14221 tatgccaatg agcaccgcct cttaaaaatt tcacacaatg aacgcttgga atttttagga
    14281 gacgctgttc tacagttatt gatttcagaa tatctatata aaaaatatcc taaaaagcct
    14341 gaaggtgacc tatcaaaact ccgtgctatg attgtccgtg aggagagttt agctggtttt
    14401 gcgcgtgatt gccagtttga ccagtttatc aagttgggta aaggggaaga aaaatctggt
    14461 ggtcgcaatc gtgacaccat tcttggtgat gcctttgaag cctttcttgg tgcccttctt
    14521 ttggataagg atgtggccaa ggtcaaggaa tttatctatc aagtcatgat tcctaaggtt
    14581 gaagcaggcg aatttgagat gattacagac tataaaaccc atctccaaga gttacttcag
    14641 gtcaatggtg atgtggctat tcgttatcag gtgatttctg aaacagggcc tgctcacgat
    14701 aaggtctttg atgtagaagt tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt
    14761 tctaagaaat tagcagagca ggaagctgcc aaaaatgccg ttgagaaggg gctggattca
    14821 tgtatttaaa ggaaatcgaa attcaggggt tcaagtcttt tgctgataag accaaggtcg
    14881 tttttgacca aggtgtgacg gcagttgttg gacccaatgg atctggaaag tccaatatta
    14941 cagaaagtct gcgttgggct ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga
    15001 tgccggatgt catctttgct ggaaccgaaa gtcgcaaacc gctcaattat gcttctgtag
    15061 ttgtgactct ggataatcat gacggattta tcaaggatgc aggtcaagaa atcagggtgg
    15121 aacgccatat ctatcgtagt ggagatagcg aatacaagat tgacggcaag aaagtccgtc
    15181 tgcgtgatat tcatgacctc ttcttggata ctggattggg acgagattcc ttctctatta
    15241 tttcccaagg gaaggttgag gagattttta attccaagcc tgaggaacga cgagctattt
    15301 ttgaagaagc tgcaggagtt ttaaaataca agactcgcag aaaagaaact gagagtaaac
    15361 tgcaacaaac tcaggataat ctagaccgct tagaggacat tatctacgag ttggataatc
    15421 aaatcaagcc tcttgagaag caagctgaga atgcctgtaa gtttttagac ttggaaggac
    15481 aacgtaaggc tatttattta gacgttctgg ttgctcaaat caaggaaaat aaggcagaaa
    15541 tagagtcgac agaagaagag ctggctcagg ttcaagaact cttgatgagt tattaccaaa
    15601 agcgtgaaaa attagaagaa gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg
    15661 ctgaaatggc caaagaccaa ggcagtttga tggacttgac tagtctgatt agtgatttag
    15721 aaagaaaatt agccctatcg aaactggagt ccgagcaagt ggccttgaat caacaggagg
    15781 cacaagctcg tttggctgct ttggaggata agagaaattc actcagcaaa gaaaagtctg
    15841 ataaagaaag ctctttagct ctgttagagg gaaatctagt ccaaaataat caaaaactca
    15901 atcgtttaga agctgaattg ctggctttct cagacgatcc tgatcagatg attgagctct
    15961 tacgtgaacg ctttgtagct cttttacaag aagaagcgga tgtctcaaac cagttgaccc
    16021 gtattgagaa tgagttggaa aatagtcgtc agctttctca aaaacaagca gatcaactag
    16081 aaaagctgaa agagcaatta gctatagcta aagagaaggc tagtcagcaa aaggaagagc
    16141 ttgaaactgc caaggagcag gttcagaaat tattggctga ctaccaagct attgccaagg
    16201 agcaagagga gcagaaaact tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg
    16261 ataatctcaa aaacaagcag gccagagctc aaagtttgga aaatatcctg agaaatcata
    16321 gtaactttta tgcaggtgtt aagagtgttc tccaagaaaa agatcgccta ggtgggatta
    16381 ttggtgcagt cagtgagcat ctgacctttg atatgcatta tcaaactgcc ctagaaattg
    16441 cgcttggagc gagtagtcag cacattattg tagaagatga gaatgcggca accaaggcta
    16501 ttgacttcct taaacggaac agagccggtc gtgcaacctt tcttcctttg accactatta
    16561 aggcgcgtac gatttctagt cagaaccaag atgctatcgc tgtaagccca ggtttccttg
    16621 ggatggcaga tgagttggtg acttttgata ctagactgga agccattttc aagaacttgc
    16681 tagctacgac ggctatcttt gataccgtag aacatgcgcg tgaagctgct cgacaagttc
    16741 gttatcaggt tcgtatggtg acattggatg ggacagaatt acgcacgggt ggttcctatg
    16801 cgggtggtgc caatcgccaa aataacagta ttgtcatcaa gccagaactg gagcaattac
    16861 aaaaagaaat tgctgcagat gaagcaagct tgggttcaga agaagcggct ttgaagacct
    16921 tgcaagacca gatggctgca ttgacagaaa gattagaagc catcaaatct caaggagagc
    16981 aggcacgtat tcaggagcaa ggcttgtccc tcgcttatca gcaaactagt cagcaagttg
    17041 aagaactgga aactctttgg aaactccaag aagaggaaat agatcgtctt tctgagggag
    17101 attggcaagc ggataaggaa aaatgtcaag agagccttgc tactatcgcc agtgaaaagc
    17161 aaaatctgga agctgagatt gaagaaatta agtctaataa aaacgccatc caagaacgct
    17221 atcaaaattt gcaggaagag gtggcgcaag ctcgcttgct taagacagaa ctgcaagggc
    17281 aaaaacgtta tgaagtagct gatattgagc gtttaggcaa ggaattggac aatcttaata
    17341 tcgaacaaga agaaattcag cgcatgctcc aagaaaaagt tgacaatctt gagaaggttg
    17401 atacagaatt gctcagtcaa caggcggaag aatccaaaac tcagaaaaca aatctccaac
    17461 aaggtttgat tcgcaagcag tttgagttgg atgatataga aggtcaactg gatgatattg
    17521 ccagtcactt ggatcaagct cgccagcaga atgaggagtg gattcgcaag caaacacgtg
    17581 ctgaagccaa gaaagaaaag gtcagcgagc gcttgcgcca tctacaaaat caattaacag
    17641 accagtacca gattagctat actgaagcac tagaaaaggc acatgaattg gaaaacctca
    17701 atctggcaga gcaagaggtg caggatttag agaaggctat tcgctcattg ggacctgtca
    17761 acttggaagc tattgaccag tacgaagaag ttcacaaccg tctggacttt ctaaatagtc
    17821 agcgagatga tattttgtca gcgaaaaatc tgctccttga aaccattaca gagatgaatg
    17881 atgaggtcaa ggaacgcttt aaatcaacct ttgaagctat tcgtgagtcc tttaaagtga
    17941 ccttcaagca gatgtttggc ggaggtcagg cagacttgat attgactgag ggcgaccttt
    18001 taacagctgg tgtggagatt tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc
    18061 tcatgagtgg tggtgaaaaa gctctatcgg ctcttgcctt gcttttctcc attattcgtg
    18121 tcaagaccat tccttttgtc atcttggatg aggtggaagc tgcgctggat gaagccaatg
    18181 ttaaacgttt tggggattac ctcaaccgct ttgacaagga cagccagttt atcgttgtaa
    18241 cccaccgtaa gggaaccatg gcagcggctg attccatcta tggagtgacc atgcaagaat
    18301 cgggtgtttc aaagattgtt tcagttaagt taaaagattt agaaagtatt gaaggatgac
    18361 aattaaacta gtagcaacgg atatggacgg aaccttccta gatgggaatg gacgctttga
    18421 tatggatcgt ctcaagtctc tcttggcttc ctacaaggaa aaagggattt actttgcggt
    18481 ggcttcgggt cggggatttc tgtctctgga aaaattattt gctgatgttc gtgatgacat
    18541 tattttcatc gcggaaaatg gcagtttggt agagtatcaa ggtcaggact tgtatgaagc
    18601 gactatgtct cgtgactttt atctggcaac ttttgaaaag ctgaaaacgt caccttatgt
    18661 agatatcaat aaactgctct tgacgggtaa gaagggttca tatgttctag atacggttga
    18721 tgagacctat ttgaaagtga gtcagcatta taatgaaaat atccaaaaag tagcgagttt
    18781 ggaagatatc acagatgaca ttttcaaatt tacaaccaac ttcacagaag aaacgctaga
    18841 agctggtgaa gcttgggtta atgaacatgt ccctggtgtt aaggccatga caactggctt
    18901 tgaatctatt gatattgttc tggactatgt cgataagggt gtagctattg ttgaattagc
    18961 taaaaaactt ggtatcacaa tggatcaggt catggctttt ggagacaatc ttaatgactt
    19021 acatatgatg caggttgtgg gacatcctgt agctcctgaa aatgcacgac ctgaaatttt
    19081 agaattagca aagactgtga ttggtcacca taaggaacgg tcggttatag cttatatgga
    19141 gggcttataa tggcagatat aaaattgatt gcattggact tggacgggac cttgctgact
    19201 actgataaaa ggctgacgga tcgtaccaag gaaaccttga aagctgcgcg tgatcgtggt
    19261 atcaaggtcg tattgacaac tggtcgtccc ttaaaagcca tggacttctt tctccatgag
    19321 ttagggactg acggccatga agatgagtat accattactt ttaatggtgg attagttcag
    19381 aaaaatacag gagaaatcct tgataaaaca gtcttttcat atgatgatgt ggcacgtttg
    19441 tatgaagaaa cagagaaatt atcactgcct cttgatgcca tctcagaagg aacagtttat
    19501 caaatccaat cggaccaaga aagtctttat gccaaattca atccagcttt gacctttgtt
    19561 ccagtggact ttgaagactt atctagtcaa atgacctaca acaaatgcgt gactgccttt
    19621 gctcaagaac ccttggatgc agccattcag aagatttctc cagaattgtt tgaccaatat
    19681 gaaatcttta aatcacgtga aatgttgcta gaatggtcac caaagaatgt tcataaagca
    19741 acaggtttgg caaaactaat cagccatctt ggaatcgacc aaagtcaagt gatggcttgt
    19801 ggtgacgagg ccaatgacct ctctatgatt gaatgggcag gtcttggtgt tgctatgcaa
    19861 aacgctgttt ctgaagtaaa ggcagccgca aatgtagtga cgccgatgac caacgatgag
    19921 gaagctgtcg cctgggctat cgaagaatat gtgctaaagg agaactaaga tatgggattg
    19981 tttgaccgtc tattcggaaa aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct
    20041 ctggaaaatc ttgatttgtc tgaagatgtt gatcctacct tcacagaagt tgaggaagtt
    20101 tctcaggaag aagcagaggt tgaaattgtt gaacaagctg tgttccaaga agaggaaatc
    20161 caagacacag ttgaagaaag tctggattta gagccagttg tagaagtttc tcaaaaagaa
    20221 gtcgaagaat ttccacactc agaagaaggg aatactgagt ttctagagac tatagaagaa
    20281 aataattctg aagttcttga agcagaaagg cctcaagcag aagaaaccgt tcaggaaaaa
    20341 tatgaccgca gtcttaagaa aactcgtaca ggtttcggtg cccgcttgaa tgccttcttt
    20401 gctaacttcc gctctgttga cgaagaattt ttcgaggaac tggaagaact gctgattatg
    20461 agtgatgttg gtgtccaagt cgcttctaac ttaacggagg aactacgtta cgaagccaag
    20521 cttgaaaatg ccaagaaacc tgatgcactt cgtcgtgtca tcattgagaa attggttgag
    20581 ctttatgaaa aggatggtag ctacgatgaa agcatccact tccaagataa cttgacagtt
    20641 atgctctttg ttggtgtgaa tggtgttggg aaaacaactt ctatcggaaa actagcccac
    20701 cgctacaaac gagctggtaa gaaggtcatg ctggttgcag cagatacctt ccgtgcgggt
    20761 gcagtagctc agctagctga atggggccga cgagtagatg ttccagtagt aactggacct
    20821 gaaaaagctg atccagccag cgtggtcttt gatggtatgg aacgtgccgt ggctgaaggt
    20881 atcgatattc tcatgattga tactgctggt cgtctgcaaa ataaggataa ccttatggct
    20941 gagttggaaa agattggtcg tattatcaaa cgtgttgtgc cagaagcacc acatgaaacc
    21001 ttcttggcac ttgatgcatc aacaggtcaa aatgccctag tacaggccaa agaattttcg
    21061 aaaatcacac ctttaacggg aattgttttg actaagattg atggaactgc tcgaggaggt
    21121 gtggttctag ccattcgtga agaactcaat attcctgtaa aattgattgg ttttggtgaa
    21181 aaaatcgatg atattggaga gtttaactca gaaaacttta tgaaaggtct cttggaaggc
    21241 ttaatctaat cagaagcaaa aatcctgcaa ggtacaaact tgcaggattt ttttattcga
    21301 aacgaccatc ttgacgatag gcgatatctg gttgccaagt ccatttggca tcgaattttt
    21361 caagtaggtc aaagctggct tgaggtccca tgcttccagc tttatagtca tgaagtgggg
    21421 caccattttc ggcccagagc tcttcaatac ggtcaatcaa cttccatgac gcaccaactt
    21481 catcccagtg gctaaagtta gttgagttgt tatttaggac atcataaatc aatttttcgt
    21541 atggttctgg agaagcacca gttgcagtcg catctgtacg gtaatcaagt gagttaggag
    21601 ccaagttaaa ttcttctcct acttgcttcc catttaggct aagagagaag ccttctgttg
    21661 gttgaatata gatggtcaaa atatttggag caagtggttc tccaaagata gaatccattt
    21721 gtttaaagac gatgttgaca tgggttcctt tttcagtcag tcgtttacct gtacggaaaa
    21781 agaaaggaac accacggaat cgatcgctgt ctacaaagaa ggcacctgat gtaaaggttt
    21841 cagttgttga ttctggattc acatttggct cgctacgata agagatgtat ttcatgccat
    21901 caatcttacc agagcggtat tgcccacgga taaagtgttc tttgagttct tcatcagttg
    21961 gatgatagag gtttttaaag accttaatct tttcagcacg aatctcgtct tttgtgaagc
    22021 ttgctggttt gtccatggcg aggagcgaaa gaagttgtag agtgtggttt tggaccatgt
    22081 cacggagggc accggattgg tcatagtagc caccacgttc ttctacaccc aagcgctccg
    22141 caaaggtaat ttgaacattg tcgataaaat ccttgttcca aacgttttca aaaatcaagt
    22201 ttgcaaagcg aactgcaaag atgctttgga tcatttcctt accaagataa tggtcgatac
    22261 ggaaaatttg ttcttcgtca aatgttgcta ggagttcgtc attcaacttg tttgcagttg
    22321 cgtaatctgt accaaatggt ttttcaacga tcaagcgctc aaaacctttg ccatcgacaa
    22381 tgttttcaga tttgaggtgt ttggcaatgg ttccaaagaa ctgaggtgcc atagacaaga
    22441 agaagagctt attgtgttca gcttggtatt tttcattaag ctcagcttgt aattgacgca
    22501 aagcaatata atgttccgaa tcattgacat catggctttg atagtagaag tggctagcaa
    22561 attcttgggc ttgctcggta ctatctgcca aatcaaggat ggactcgaca actacagatt
    22621 caaaatattc cttactccaa ggtctacggg cagttccaat aacggcaaag tgcttggaaa
    22681 gattgccgga tttatatagt ctaaaaaggg aagggtagag cttgcgttta gccaggtctc
    22741 cactcgcacc gaaaattgta acaataacct tagatgacat ctagctacct aatttctatt
    22801 tttattccta gtcttgctag gtatgaggaa acctcatttc ataaacttaa ttctaacata
    22861 attttccgaa aaatcaaaaa ttccaatacg aggtagaaaa actgcaagga aatccttaca
    22921 gtttgagttt agacgtttaa gaccttatct aagaactctt tcagacgagg gtgttgtggg
    22981 ttatcaaaga tttggtcagg tgttccgtct tcaaggaact cgccatctgc agtaaagata
    23041 acgcggttgg caacctgacg agcaaatccc atctcatggg ttacgataat catggtcatg
    23101 ccttgctcag ccaattcctt cataacgtta agtacgtctc caaccatctc agggtcaagg
    23161 gcagaagttg gttcatcgaa gagcatgatg tctggattca ttgctaggcc acgagcgatg
    23221 gccacacgtt gtttttgacc acctgatagg ctatctggat tggcattagc tttatctgct
    23281 agtccaacct tttcaagcaa ctccattccc aattcctcag cttcttcctt agtcatcaac
    23341 ttgtgctcaa taggagcaaa ggtgatgttg tccaatacag acatatgagg gaagaggttg
    23401 aagtgttgga ataccatgcc gatattttca cggacgtggt caacattggt tgttttttca
    23461 gttaaatcat agccgttcac agtgatgtga ccgctagtga cttcttctaa aagattgagg
    23521 ctacggagga aagttgactt accagaacct gaaggaccga tgatacaaac aacatctcct
    23581 tcatagaact tagtcgtaat tccttttagg acttcatttt ttccatagtg cttgtgtaaa
    23641 tcatttacat caatttttaa ttttgccatt aacgaatcct cttttctaag cgtttcgcta
    23701 gtctagtcaa aagtgtgata attacaagat agaagatagc aaggattgca tacatcttga
    23761 aactttggta gttacgagca atgataatct taccagtttg gaagagttca accaaaccga
    23821 tagcagatac gatagttgta tctttaagag cgataacgaa ttggttgaca aagtttggca
    23881 acatcaattt agttgcttgt ggcaagataa tcttacgcat ggtttttcca taagagatac
    23941 ccaagcttcg gctggcttcc atttggccaa ctggaacggc ctgaatacca ccacgaacga
    24001 tttcagcgat ataagcagcc gcattgagtg agagggcaat ggttccagct acaaagtcgt
    24061 taattgggct ttgttggcct gtgatagact cgatgaagtt tggaattccc cagaagatga
    24121 aggctgcaag aatcatcaat ggaataccac gaataacgtc aacgaaaatc tcagagatga
    24181 cgcgaagaga tttgtatggg ctaacgctaa acataccgaa gataattccg atgacaatgg
    24241 caatagcaaa tgagataaga gctagagcaa gagtgatacc aagaccgcta aggagttgtt
    24301 tgtagttgtt ttgaagcaag ccccagagcg ttgtttcgtc aacagtactt gttgaagcag
    24361 ttgaagattc gctagctagg tatttgtcaa gaatcttttg gaattcaccg tttgccttaa
    24421 ggtttgcaag tccgttgttg aacatttcaa tcagttctgg atttgctcct tttttaacgg
    24481 caaaggctgt ttcaccgatt ggagttccag agattggagt tttcaatttt tgaccttggc
    24541 tgatagaata tttgagaaca ggttcatcat ccataacggc atcaatggca ccagtgttta
    24601 aactgtcata cattgaagaa ccatcagcaa aggttttgat tttgtaaccg tatttgcttt
    24661 gattttctgt taggaaggtt tgagaagcag ttccgttttt aacaccgact gtctttcctt
    24721 ttagatcttc ataagaagca atattgcttg attctttgac accaagaatg gtattagcag
    24781 tgtagtatga ttctgagaag tcaaaagttg ccttacgagc atctgtgaca gacataccag
    24841 caatgatacc atcggcttga ccagcttgga cagcactgat agcagcatca aaaccagggt
    24901 tggtgatttc aatttcaaaa ccttggtctt tagcgattgc cttaatcaat tccatatcaa
    24961 taccagtgta ttggttgctt gaattttgga aaacaaaagg tgcaaaagaa gaatcgctgg
    25021 caatgatata tttagcctta acaggaatag cttttaatcc tgcgagagta gttgtagttg
    25081 gcactgctga agatgatgaa gcagtccatt tcttgataat tttatcaaga ctaccatctt
    25141 ttttcatttc agccaaggct tggttaaatt cagtaaccag gtgctcgtat ttacttcctt
    25201 ttttcacacc gaaagcaaaa cttcctacag cttcaccatc catttcaata tggaggtctt
    25261 gaccttggtt aatggcatat tcgataacag gtttgtcatc catcatggca tcgatggcac
    25321 cagcactcaa gctgttgttc attaaatcac cagtgtcaaa tgttttaata gtaaagccgt
    25381 atttatcttt gattgtttca aggaaacgtt gagcggcagt tccgttttta acaccaacgg
    25441 ttttgccagt taattggtcg tacttgctaa ttttgtgtga ctttgtagta gcaatgacaa
    25501 cttttgtatc atagtaagta tcagacatgg tgaagacttt ttcacgttct ttagtctttg
    25561 tcatccctgc catgatagcg tcggcttgcc cagcttgaac cgcattgacc gctgcgtcaa
    25621 atccaggata ggacatctga atgttccagc ctttaatctc agcgactttg ttaataatgt
    25681 caacatcaat tcctttataa gtttgatctg aatctttaaa ctcaaaaggt gcataggcgg
    25741 tatcagaaac aatcttaatc gtttctgctt tggcaatacc taatgagaaa attgggaata
    25801 aaattagcaa aaatgctaga aattttttct tcatttttag tctccttttc cgaatattct
    25861 ctcattatat cagaaaaagt aaaaaaaggc aaatttttat attttccgtg tcagaaaata
    25921 taacattgat ttttcctttt ctttcttgaa ttgctattaa aaagtgctat aataatagta
    25981 tatatagaag aaaagaggac ggggatatga agaataaaag aatatttaaa gacttccaag
    26041 cttcaaaaat gaatttaaac atttacacaa gccccttgtt agcctttgtt tttgtcttca
    26101 taggagagtt tgtggcttat actttatatg gtattagttt gttagctctc atcggacttg
    26161 ctagaaattt tggagaggct ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga
    26221 gcttgacgga taaaacaagt gactttcgtt taattttagg attactggcc tttggtttta
    26281 ttcttaacac tgtgttcaga tggacaagaa aagttgagaa aagacctatt cgaaccttgg
    26341 gattttatag agagaatttc ctcagcaatc ttctgaaagg atttagtcta ggcctggcac
    26401 tttttcttct gaccttgtta ggtttagtgg tcttaggtca atatcgtttg gaatccattc
    26461 acttgaatcc ttattctctt gcctttgtcg tctttactat cccattttgg attttacagg
    26521 ggacagcaga agaagtggtg gcccgtgctt ggctacttcc tcaattggcc tcaagaacca
    26581 atctaaaact agctattctt atatctagcc tgttctttac cctgcttcat atgggcaatt
    26641 ctggcctcac ccctctatct ctagtaaatc tctttttatt cggagttgcc atggctcttt
    26701 accttctcaa aactgataca gtttggggtg ttgcaggtat tcatggtgct tggaattttg
    26761 ctcagggtaa tctctttggg attttagtta gtggtcaacc gtcaggaacg tctctgatga
    26821 cctttttacc acaaggcaat caagattggc tatcaggtgg ttcttttggc atagaaggtt
    26881 ccattatgac aagtctggta ttactactgc tgattgtcta tcttgctaat aaattaaaga
    26941 aagaaaatga aaggatgtga cttcggtccg tccttttctt cgtgaaaata ctataagtat
    27001 gctaaaatag gaatagcaca tggagagagg attcttatga tcaatcacat tacagataat
    27061 caatttaaac tagtatcaaa atatcaacca tcaggagatc aaccccaagc tatcgagcag
    27121 ttggtggata acattgaggg gggagaaaaa gctcagattc tgatgggggc gactggaaca
    27181 gggaagacct atactatgag tcaggtcatt tctaaagtca ataaaccaac tctggttatt
    27241 gcccacaata aaactctggc tggtcagctc tatggggagt ttaaggaatt tttccctgaa
    27301 aatgcagttg agtatttcgt atcctactat gattattacc agccagaggc ctatgtccct
    27361 tctagcgata cctatattga gaaggatagt tctgtcaatg acgagattga caagcttcgc
    27421 cactcagcta cctcagccct tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct
    27481 tgtatctatg gtttgggttc gcccaaggaa tacgctgata gtgtcgttag tctccgtcct
    27541 ggtctagaga tttctcgtga taaactcttg aatgacttgg tcgatattca gtttgaacgc
    27601 aatgatattg atttccaacg cggaagattt cgcgttcgtg gggatgtggt agagattttc
    27661 ccagcttccc gagatgaaca tgcctttcga gtagaatttt ttggagacga aattgaccgt
    27721 attcgtgaag ttgaggctct gacaggtcag gtgttgggag aagtggatca tttagcgatt
    27781 ttcccagcga cacactttgt gaccaatgac gaccacatgg aagttgccat tgcaaagatt
    27841 caggccgagt tggaagaaca attagctgtc tttgaaaagg aaggtaaact gcttgaagcc
    27901 cagcgtttga aacagcggac agagtatgat atcgaaatgt tgcgtgagat gggctatacc
    27961 aatggggttg aaaattattc tcgccacatg gatggacgga gcgaaggaga gcctccttat
    28021 acgcttctcg acttcttccc agatgatttc ttgattatga ttgacgagag tcatatgacc
    28081 atagggcaaa tcaagggcat gtacaatgga gaccgttcgc gtaaagaaat gctggttaat
    28141 tatggtttcc gtttgccgtc tgctttggac aatcgtcctc tacgtcggga ggagtttgag
    28201 agtcacgttc atcagattgt ttacgtttca gcgacacctg gtgactatga aaatgaacag
    28261 accgagacag tgattgagca aatcattcgt ccaacgggac tcttggatcc agaggtggaa
    28321 gtccgtccga ctatgggaca gattgatgac ctcttgggtg aaatcaatgc ccgcgttgaa
    28381 aaaaatgagc gtacctttat cacaactttg accaagaaaa tggcagagga cttgaccgac
    28441 tacttcaagg aaatgggtat caaggtcaag tacatgcact cggatatcaa gaccttggaa
    28501 cggacggaga ttatccgtga cctgcgcttg ggtgtctttg atgtcttggt cggaattaac
    28561 ctgctccgtg aaggaattga cgttcctgaa gtgagcctcg tagctattct cgatgctgac
    28621 aaggaaggtt tccttcgcaa cgaacgtgga ctcatccaga ctattggacg tgctgctcgt
    28681 aacagtgaag gccatgtcat catgtatgca gacacggtta cccagtctat gcaacgtgct
    28741 atcgatgaaa ctgcccgccg tcggaaaatt cagatggcct ataatgaaga gcatggtatc
    28801 gtaccacaga caatcaagaa agaaatccgt gacctgattg ccgtgaccaa ggcagttgct
    28861 aaggaagagg acaaggaagt cgacatcaat agcctcaaca aacaagagcg caaagaactc
    28921 gtcaagaaac tagaaaaaca aatgcaagaa gccgtcgaag tgcttgactt tgaactggcg
    28981 gctcagatcc gtgatatgat gttggaagtc aaggccttgg attaggggaa tagtatgatt
    29041 tatttaagaa agttaaagag agaagatttg atgtctttat gggaaatggc ttattcacaa
    29101 cttaatccag tttggaaaca gtatgatgct ccctattatg atgattatca gtatttttca
    29161 aattttaaag aattcgaact acaaaaatca gaatccattt taagcaactc aaatcgcctt
    29221 ggtatttttg ttgatgataa actagttggg actgtttcgc gttattgggt atgtaaacaa
    29281 acaagatgga tggaattggg aattggtatt tatgataaaa aattctggaa cactggtatt
    29341 gggaaagttg ctatgttgca gtggatagat aggacgtttc aggattactt ggagttggag
    29401 catctgggtt tgacaacttg gtcaggaaat cttggtatga tgaaacttgc tgaaaaatta
    29461 agaatgaaaa aagaagctca tattccaaaa gttcgttatt atcaaggtaa atattttgat
    29521 agtattaaat atggtatttt gagagaagac tgggagaaaa tgaatgacgg ttattatcaa
    29581 atcaatggaa actcctgaag agatagaagg taaatccctt gttcactggc aaacgtggag
    29641 agaggcttat gatgaccttt tgcctgcaga atttcaggag acaatgacat tagaaagatg
    29701 tcgattcttt agtcaaaagt atccagaaaa tacattgatt gcgataggtg atctgaaggt
    29761 agttggtttt atcagttatg gtaactttcg tgatgagact attcaagctg gtgaaattat
    29821 tgctttatat gttttaaaag actattacgg aaaaggcata gcacaaaagt taatgaaagc
    29881 agctttgact gctctgaatc atttttctga aattttctta tgggtattga aagataacaa
    29941 gcgagccatt gctttctatc aaaaaatggg ttttactttt gatggacaag aaaagatact
    30001 tgaacttgga aagcctataa aggaaaaacg aatggtattc tattctaaaa taattttaaa
    30061 aagtagaagc taatggcact ggtaccaagt ctgaaaattt aataaattag aaagcgagta
    30121 aatttatgtc ccgttcccaa ttaacgattt taacaaatat ttgtctgatt gaagaccttg
    30181 aaactcagtg cgtggttatg cagtaccgtg ctcctgaaac caatcgctgg tctggttatg
    30241 cctttcctgg aggtcatgta gaaaatggtg aggcttttgc ggagtctgtc attcgtgaaa
    30301 tctacgaaga aacaggattg actatccaaa atccgcaact ggtaggtgtt aaaaattggc
    30361 ctttggatac aggggggcgc tacattgtct tttgttacaa ggcgaccgag tttactggaa
    30421 ctcttcaatc ttcagacgag ggagaagttt cttgggtgca aaaagaccag attccaaact
    30481 tgaatctggc ctatgatatg ctaccattga tggaaatgat ggaagctccc gacaagtcag
    30541 agtttttcta ccctcgccgt acagaagacg attgggaaaa gaaaatcttc tagtctttta
    30601 ctaaataacc tagctgatcc aaggcttcct cgatatagtg gaggtcttgt tgtgtttcgg
    30661 cttcgactag gtggtaatgg atgccatctg tcaattcaga tagaggtcta aagtcagaat
    30721 gctcgacttg ttctagaaaa tgttgcacat ctctgcgaca agacagttta agcaaggttt
    30781 caatttctcc ataaacggga tggtcaatca aggtattctg gacatgccca ccattatcga
    30841 caatagcaag gagttcctga ccgatttctt caacttgatg tttcactttg aaaagtttgt
    30901 gaacataagg attggtatca atttgcttat agatgtagcc acgattggtg gataggatag
    30961 gagcgccatc ggctctcaaa attgcaatgt cctgcacaat gacctgacgt gtgacatgaa
    31021 aatgttccgc caaactttgg ccattaaggg ctttaggagc ttctttcaag agttggagca
    31081 gggcttgttt gcgatctttt gtcatagctt ttccttttaa cggcgttttc gaagcacttt
    31141 atagacagct agtgctaatg tatagtctac catactatgg ataattgtgc caaatccaac
    31201 tagtacaaat agaacataga acatgttttc tacattggta cccgaagttg cgtaaaaaag
    31261 gacacaggct aatacttcag caagggcatg aacaacagcc aaaacaaaat tgaaaaccca
    31321 ggaagatttt ggtttatcta gggtatcggg gaatttttgt aggtaaagag ctcctaaagc
    31381 accaaaagat atatgggaaa aagcccgaaa aacgataacc atgggatagc cagccatcaa
    31441 aaatccaaaa ctagaggcta ggatgacaaa aactgccatc aagggcgaca agaacatggc
    31501 tataaaaata gcgatgtggc tccccaaagt ataggaagca ggtggaatga caatcttgaa
    31561 aggcataaca attggaatca aaatcgcaat agccgttaaa agggctgtca ttgtcataaa
    31621 ttgtgtcttt ttccgtgtat tcacaagaat ctccttttta actgcatata cactagtatg
    31681 gtacaataaa ccagacaata aagcaagaat ttacttgggt ttatagatca ttttttagtt
    31741 aaaag
//
LOCUS       DBERAE010000025        28635 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.25, whole genome shotgun sequence.
ACCESSION   DBERAE010000025 DBERAE010000000
VERSION     DBERAE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.25"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            143..2125
                     /locus_tag="ACL70N_001294"
     CDS             143..2125
                     /locus_tag="ACL70N_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0590087.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2426..7729
                     /locus_tag="ACL70N_001295"
     CDS             2426..7729
                     /locus_tag="ACL70N_001295"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGS0590088.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7896..10055)
                     /gene="pbp1a"
                     /locus_tag="ACL70N_001296"
     CDS             complement(7896..10055)
                     /gene="pbp1a"
                     /locus_tag="ACL70N_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGS0590089.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10052..10648)
                     /gene="recU"
                     /locus_tag="ACL70N_001297"
     CDS             complement(10052..10648)
                     /gene="recU"
                     /locus_tag="ACL70N_001297"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGS0590090.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10714..11241
                     /locus_tag="ACL70N_001298"
     CDS             10714..11241
                     /locus_tag="ACL70N_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGS0590091.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11311..11640
                     /gene="gpsB"
                     /locus_tag="ACL70N_001299"
     CDS             11311..11640
                     /gene="gpsB"
                     /locus_tag="ACL70N_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGS0590092.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11661..12041
                     /gene="rnpB"
                     /locus_tag="ACL70N_001300"
     ncRNA           11661..12041
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL70N_001300"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12126..13283
                     /locus_tag="ACL70N_001301"
     CDS             12126..13283
                     /locus_tag="ACL70N_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGS0590093.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13296..14690
                     /gene="mapZ"
                     /locus_tag="ACL70N_001302"
     CDS             13296..14690
                     /gene="mapZ"
                     /locus_tag="ACL70N_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGS0590094.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14766..16190
                     /gene="gndA"
                     /locus_tag="ACL70N_001303"
     CDS             14766..16190
                     /gene="gndA"
                     /locus_tag="ACL70N_001303"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGS0590095.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSHKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16202..16891
                     /locus_tag="ACL70N_001304"
     CDS             16202..16891
                     /locus_tag="ACL70N_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0590096.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVAYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESVTETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            16989..17945
                     /gene="cbpC"
                     /locus_tag="ACL70N_001305"
     CDS             16989..17945
                     /gene="cbpC"
                     /locus_tag="ACL70N_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGS0590097.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEPKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYFGNKWYYLNAGN
                     GDMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNGEWVQ"
     gene            18067..18945
                     /gene="mvk"
                     /locus_tag="ACL70N_001306"
     CDS             18067..18945
                     /gene="mvk"
                     /locus_tag="ACL70N_001306"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGS0590098.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            18927..19880
                     /gene="mvaD"
                     /locus_tag="ACL70N_001307"
     CDS             18927..19880
                     /gene="mvaD"
                     /locus_tag="ACL70N_001307"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGS0590099.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            19867..20874
                     /locus_tag="ACL70N_001308"
     CDS             19867..20874
                     /locus_tag="ACL70N_001308"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGS0590100.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            20858..21868
                     /gene="fni"
                     /locus_tag="ACL70N_001309"
     CDS             20858..21868
                     /gene="fni"
                     /locus_tag="ACL70N_001309"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGS0590101.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDNS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            21945..22643
                     /gene="liaF"
                     /locus_tag="ACL70N_001310"
     CDS             21945..22643
                     /gene="liaF"
                     /locus_tag="ACL70N_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGS0590102.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            22640..23635
                     /locus_tag="ACL70N_001311"
     CDS             22640..23635
                     /locus_tag="ACL70N_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0590103.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            23649..24281
                     /locus_tag="ACL70N_001312"
     CDS             23649..24281
                     /locus_tag="ACL70N_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0590104.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            24357..25050
                     /locus_tag="ACL70N_001313"
                     /pseudo
     CDS             24357..25050
                     /locus_tag="ACL70N_001313"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25200..25439
                     /locus_tag="ACL70N_001314"
     CDS             25200..25439
                     /locus_tag="ACL70N_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590105.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            25520..26341
                     /gene="cbpG"
                     /locus_tag="ACL70N_001315"
     CDS             25520..26341
                     /gene="cbpG"
                     /locus_tag="ACL70N_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGS0590106.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            26360..27382
                     /gene="cbpF"
                     /locus_tag="ACL70N_001316"
     CDS             26360..27382
                     /gene="cbpF"
                     /locus_tag="ACL70N_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGS0590107.1"
                     /translation="MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAINTTVGGYYLNY
                     NGEWVK"
     gene            complement(27510..28635)
                     /locus_tag="ACL70N_001317"
                     /pseudo
     CDS             complement(27510..28635)
                     /locus_tag="ACL70N_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         8709 a         5164 c         6539 g         8223 t
ORIGIN      
        1 tatagttgag ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat
       61 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
      121 gaaagtttta aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac
      181 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
      241 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc
      301 taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg
      361 ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac
      421 ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc
      481 ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata aaaaatcaga
      541 tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat
      601 caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt
      661 gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa
      721 tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc caagtagtct
      781 cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg ttgaatttgc
      841 gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta aattgtcatt
      901 ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc
      961 agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta tgaaggacaa
     1021 tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca
     1081 gtcctataaa tatacatcta agaccagtga agaacaaaaa acatctacga aaaaggctct
     1141 cttaaacaag gatttccgtc aggctattgc atttggattt gaccgtacag cctatgcctc
     1201 tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg ttccaccaac
     1261 atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta
     1321 tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga
     1381 aaaagccaag gctgaatttg ctaaagctaa atcagcttta caagcagaag gtgtgacttt
     1441 cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc agcgcgtcca
     1501 atctatgaaa caatccttgg aagcaacttt aggagcggat aatgtagtca ttgatattca
     1561 acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggtga
     1621 agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta
     1681 ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag ggtttgactc
     1741 aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac
     1801 tgaggctggt gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca
     1861 agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat
     1921 cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata aaggcacaag
     1981 tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata
     2041 ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga
     2101 agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc
     2161 cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta ctgaccccca
     2221 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     2281 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     2341 ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta aacgcttgct
     2401 aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     2461 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     2521 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccagctga
     2581 tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg aagcgcctaa
     2641 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
     2701 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
     2761 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
     2821 acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
     2881 aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg gcttgaccgt
     2941 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg aaaagggcaa
     3001 atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt ttgtcggtta
     3061 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
     3121 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
     3181 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
     3241 agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg cgggctctta
     3301 tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg taaaagcgga
     3361 tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
     3421 tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc gtgtcaagga
     3481 atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
     3541 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
     3601 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgcct
     3661 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
     3721 cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta gtttcctcgg
     3781 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
     3841 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
     3901 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
     3961 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
     4021 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
     4081 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
     4141 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
     4201 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
     4261 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
     4321 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
     4381 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
     4441 tggtgtcgaa gacttcaaga ccctgattga gaaggctaag aaatatggag ctcatctagg
     4501 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
     4561 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
     4621 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
     4681 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
     4741 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
     4801 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
     4861 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
     4921 ccgtaaccac caaaaagatg cttgggtagg ggactacaga agttatggtg gtgcagccaa
     4981 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
     5041 ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt acttccaaca
     5101 cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
     5161 ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata ataaagtagt
     5221 tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta cagtaacgct
     5281 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
     5341 tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc aggccggtac
     5401 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
     5461 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttaccctaga
     5521 tcttctagca aatcaaccat acgtacttta ccgttcaaaa caaaccaatc ctgaaatgtc
     5581 atggagtgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
     5641 gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
     5701 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
     5761 accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
     5821 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
     5881 caactatgta aaagcctacg cccacaatac acgtcgtaac aatgctacag ttgacgatac
     5941 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct caaatgttac
     6001 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
     6061 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
     6121 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg ttgaaggtgt
     6181 tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac gtggttggaa
     6241 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
     6301 gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg aagcaggtaa
     6361 gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg cttttgtagt
     6421 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
     6481 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggtaacct tccttgtgac
     6541 aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg caagtaatac
     6601 tcgtagtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
     6661 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
     6721 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
     6781 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
     6841 gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
     6901 agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
     6961 tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg taggcaagcc
     7021 tgcaaccatg gtcttgaaag aagcaactga aatcactgga cttcgttatg ttccacgtgg
     7081 atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa
     7141 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
     7201 tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt acggagatgg
     7261 tggcgataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
     7321 acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat taacagacaa
     7381 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
     7441 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
     7501 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gctctttagt
     7561 ttccaatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag aaacacctga
     7621 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc tagcaagtgt
     7681 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
     7741 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
     7801 aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca atagtgctat
     7861 gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
     7921 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
     7981 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
     8041 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga
     8101 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
     8161 tctggattgc ttccttcaga cagataggtc atcatagagc ggtaaacttt ggcagcgacc
     8221 gtaagaccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt
     8281 gaatatttac gcgtatagcc agcaaatagt tcatcaggtg ctacaaattg agaggtcttg
     8341 atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg
     8401 agccaagcaa gataggcatt tcgtccagtt ccataactca agactgtttt catcatgtcg
     8461 gtcatcatat aggctgtcgt ttccttcatg gcacgagttc cgacattaga gaactctttt
     8521 tcactcccat cactaaagac gactttatgg atatacattg gtttatagta agttccacca
     8581 tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct
     8641 gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattccg
     8701 agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct
     8761 gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta
     8821 tcccagttat aaacaggggt atttgtccca gggtagttat agggctcatc gtgaacgata
     8881 gtagcagttg aatcgtagat accgtactcc aaggcaggag catagtctgt gatcggtttc
     8941 atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta
     9001 cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg
     9061 gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata
     9121 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
     9181 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
     9241 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
     9301 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
     9361 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
     9421 gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
     9481 ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta
     9541 tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac
     9601 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
     9661 aacttaatca actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg
     9721 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
     9781 tcttcgatag aaacgattgc tttaaccaaa tctgtgggaa tatcattagc ttgggcattg
     9841 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
     9901 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
     9961 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
    10021 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
    10081 ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat
    10141 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
    10201 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    10261 agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
    10321 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
    10381 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    10441 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
    10501 gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    10561 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatgtttgt cttttttgtg
    10621 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
    10681 attataccat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
    10741 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
    10801 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
    10861 gggactttgg gctttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
    10921 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
    10981 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ctatcctcgc
    11041 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
    11101 tcctatcttt tttatgatga agaaaatgaa acaaaactag cttattttta ccaaaagatg
    11161 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
    11221 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
    11281 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
    11341 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
    11401 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
    11461 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
    11521 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
    11581 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
    11641 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
    11701 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
    11761 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
    11821 taggcttgaa agtgccacag tgacgaagtc tttctggaaa cagagagagt ggaacgcggt
    11881 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
    11941 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
    12001 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
    12061 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
    12121 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
    12181 ttggtcgtga agtgcgagag ttgggctacg attgtcagat tgaaaatgga cgtgttcgtt
    12241 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gctgcgggca gcagatcgta
    12301 tcaaaattat cgtaggaacg ttccctgcta agacttttga agagctattt cagggagttt
    12361 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    12421 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    12481 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    12541 gcccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    12601 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    12661 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    12721 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    12781 tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    12841 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    12901 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    12961 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta tgttccgata
    13021 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    13081 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    13141 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    13201 agcgtaagtt atacaacgga accttgaaag tggatctgta tcaatatttt ggtcagcgtg
    13261 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    13321 aaaaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    13381 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    13441 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    13501 aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc
    13561 gtgaggctgt agagaagtca gaagcttctt cggaggaagt tccatcttct gaagacatct
    13621 tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg
    13681 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    13741 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    13801 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    13861 aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac
    13921 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    13981 aactgaatca actcaagact ttacttgata agctggaagg tagtcgtgaa catacgcttg
    14041 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc
    14101 aatttgagaa accagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg
    14161 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    14221 ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaaacta
    14281 gcagctcaag ttcaagtcaa gcaagttcaa atacgactag tgagccaaaa ccaagtagtt
    14341 caaatgagac tagaagtagt cgcagtgaag tcaatatggg tctctcgagt gcaggggttg
    14401 ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc tgctattgat gatagtaata
    14461 actctgcctg ggattttgcg gatggtgtct tggaacaaat tctagcgact tcacgttcac
    14521 gtggctatat cactggagac caatatatcc ttgaacgtgt caatatcgtt aacggcaatg
    14581 gttattacaa cctctataag ccagatggaa cctatctctt tacccttaac tgtaagacag
    14641 gctactttgt cggaaatggc gctggtcatg cggatgactt ggactactaa gcagtcgtta
    14701 caaaattctt tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa caagaggagt
    14761 gtcaaatgac aaaagctaac tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg
    14821 cccttaatat tgaatcacgt ggttacacag ttgctatcta caaccgtagt aaagaaaaaa
    14881 cggaagatgt gattgcttgc catcctgaaa agaattttgt accaagctat gacgttgaaa
    14941 gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa gctggacctg
    15001 gtacagatgc tactatccaa gcccttcttc cacaccttga caagggtgat atcttgattg
    15061 acggaggaaa cactttctac aaagatacca tccgtcgtaa tgaagaattg gcaaactcag
    15121 gtatcaactt tatcggtact ggagtttctg gtggtgaaaa aggtgccctt gaaggtcctt
    15181 ctatcatgcc tggtggacaa aaagaggcct acgaattggt tgcggatgtt cttgaagaaa
    15241 tctcagctaa agcaccagaa gatggcaaac catgtgtgac ttacatcggc cctgatggag
    15301 ctggtcacta tgtgaaaatg gttcacaatg gtattgagta cggtgatatg caattgatcg
    15361 cagaaagcta tgacttgatg caacacttgc taggcctttc tgcagaggat atggctgaaa
    15421 tctttactga gtggaacaag ggtgaattag acagctattt gatcgaaatc acagctgata
    15481 tcttgagcca taaagacgat gaaggccaag atggaccaat cgtagactac atccttgatg
    15541 ctgcaggtaa caagggaact ggtaaatgga ctagccaatc atctcttgac cttggtgtac
    15601 cattgtcact gattactgag tcagtgtttg cacgctacat ttcaacttac aaagaagaac
    15661 gtgtatatgc tagcaaggtg cttccaaaac cagctgcctt caactttgaa ggagacaagg
    15721 ctgaattgat tgaaaagatc cgtcaagccc tttacttctc aaaaatcatt tcatacgcac
    15781 aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg ccatttgcag
    15841 atatcgcatc tatctggcgt gatggctgta tcatccgttc tcgtttcttg caaaagatta
    15901 cagatgctta caaccgcgat gcagatcttg ccaaccttct tttggacgag tacttcttgg
    15961 atgttactgc taagtatcaa caagcagtgc gtgatatcgt agctcttgcg gttcaagctg
    16021 gtgtgccagt gccaactttc tcagcagcta ttacttactt tgatagctac cgttcagctg
    16081 accttccagc taacttgatc caagcacaac gtgactactt tggtgctcac acttaccaac
    16141 gtaaagacaa agaaggaacc ttccactact cttggtatga cgaaaaataa gtaggtcagc
    16201 catggggaaa cggattttat tacttgagaa agaacgaaat ctagctcatt ttttaagttt
    16261 ggaactccag aaagagcagt atcgggttga tctggtagag gaggggcaaa aagccctctc
    16321 catggctctt cagacagact atgatttgat gttattgaac gttaatctgg gagatatgat
    16381 ggctcaggat tttgcagaaa aattgagtcg aactaaacct gcctcagtca tcatgatttt
    16441 agatcattgg gaagacttgc aagaagagct ggaagttgtt cagcgttttg cagttgcata
    16501 catttataag ccagtcctta tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg
    16561 tcgggacttc attgatcaac actgcagtct gatgaaagtt ccaaggactt accgcaatct
    16621 taggatagat gttgaacatc acacggttta tcgtggtgaa gagatgattg ctctgacccg
    16681 ccgtgagtat gaccttttgg cgacacttat gggaagcaag aaagtattga ctcgtgagca
    16741 attgttggaa agtgtttgga agtatgaaag tgtgaccgag acaaatatcg tagatgtcta
    16801 tatccgctat ctacggagca agcttgatgt taaaggccaa aaaagctaca ttaaaaccgt
    16861 gcgtggtgtt ggatatacca tgcaagaata gataagcagt tgcagttgtg taactgcttt
    16921 tttgaggagt ttttatatat tgacatgcag tcgggtcttt gctacaatcg ttttaggagg
    16981 atatatagat gaaacttttg aaaaaaatga tgcaagttct actagcagtc tttttctttg
    17041 gtttgctagc tacaaatacg gtatttgcga ataccacagg tggccaattt gttgataagg
    17101 ataatagaaa atattatgta aaagatgatc ataaagcaat ctattggcat aaaatagacg
    17161 gtaaaactta ctattttggt gatattggag agatggttgt cggttggcaa tacttagaaa
    17221 ttcctggaac aggttatcgt gataatttat tcgataacca accagttaat gagattggcc
    17281 ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa acagataaac
    17341 aagtactaga gccaaaaacg tctgaaaata caggaaaagt atacggtgaa caatatcctc
    17401 tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag acaggctgga
    17461 tttatgaaga cggcaattgg tattatttaa ataagctagg aaattttggc gatgattctt
    17521 acaatccact accaattggt gaagttgcta agggttggac tcaagatttt catgttacta
    17581 ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca ggtaagatgc
    17641 ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct ggttctatgg
    17701 caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa aatggtgata
    17761 tgaaaacagg atggcaatac tttggtaaca agtggtacta cctaaatgca ggtaatggag
    17821 acatgacgac aggttggttc caggtcaatg gcagatggta ctacgcttat agctcaggtg
    17881 ccttggcagt gaatacgacc gtagatggct attctgtcaa ctataatggc gaatgggttc
    17941 aataatgaaa gaagcgattg tgaatggaaa caatcgcttt ttttgtgaaa atataataaa
    18001 atagatagga aagaattaat acttgtatga aaaataagac gttttttcgt ctagtaaaag
    18061 gaaaaaatga caaaaaaagt tggtgtcggt caggcacata gtaagataat tttaataggg
    18121 gaacatgcgg tcgtttacgg ttatcctgcc atttccctgc ctcttttgga ggtggaggtg
    18181 acctgtaagg tagttcctgc agagagtcct tggcgccttt atgaggagga taccttgtcc
    18241 atggcggttt atgcctcact ggagtatttg aatatcacag aagcctgcat tcgttgtgag
    18301 attgactcgg ctatccctga gaaacggggg atgggttcgt cagcggctat cagcatagcg
    18361 gccattcgtg cagtatttga ctactatcag gctgatctgc ctcatgatgt actagaaatc
    18421 ttggtcaatc gagctgaaat gattgcccat atgaatccta gtggtttgga tgctaagacc
    18481 tgtcttagtg accaacctat tcgctttatc aagaacgtag gatttacaga acttgagatg
    18541 gatttatccg cctatttggt gattgccgat acgggtgttt atggtcatac tcgtgaagcc
    18601 atccaagtgg ttcaaaataa gggcaaggat gccctaccgt ttttgcatgc cttgggagaa
    18661 ttaacccagc aagcagaagt tgcgatttca caaaaagatg ctgaaggact gggacaaatc
    18721 ctcagtcaag cgcatttaca tttaaaagaa attggagtca gtagccctga ggcagacttt
    18781 tgggttgaaa cgactcttag ccatggtgct ctgggtgcca agatgagcgg tggtgggcta
    18841 ggaggttgta tcatagcctt ggtaaccaat ttgacacacg cacaagaact agcagaaaga
    18901 ttagaagaga aaggagctgt tcagacatgg atagagagcc tgtaacagta cgttcctacg
    18961 caaatattgc tattatcaaa tattggggaa agaaaaaaga aaaagagatg gtgcctgcta
    19021 ctagcagtat ttctctaact ttggaaaata tgtatacaga gacgaccttg tcgcctttac
    19081 cagccaatgt aacagctgac gaattttaca tcaatggtca gctacaaaat gaggtcgagc
    19141 atgccaagat gagtaagatt attgaccgtt atcgtccagc tggtgagggc tttgtccgta
    19201 tcgatactca aaacaatatg cctacggcag cgggtctgtc ctcaagttct agtggtttgt
    19261 ccgccctggt caaggcttgt aatgcttatt tcaagcttgg attggataga agtcagttgg
    19321 cacaggaagc caaatttgcc tcaggttctt cttctcggag tttttatgga ccactaggag
    19381 cctgggataa ggatagtgga gaaatttacc ctgtagagac agacttgaaa ctagctatga
    19441 ttatgttggt gctagaggac aagaaaaaac caatctctag ccgtgacggg atgaaacttt
    19501 gtgtggaaac ctcgacgact tttgacgact gggttcgtca gtctgagaag gactatcagg
    19561 atatgctgat ttatctcaag gaaaatgatt ttgccaagat tggagaatta acggagaaaa
    19621 atgccctggc tatgcatgct acgacaaaga ctgctagtcc agccttttct tatctgacgg
    19681 atgcctctta tgaggctatg gactttgttc gccagcttcg tgagaaagga gaggcctgct
    19741 actttaccat ggatgctggt cccaatgtta aggtcttctg tcaggagaaa gacttggagc
    19801 atttatcaga aattttcggt catcgttatc gcttgattgt gtcaaaaaca aaggatttga
    19861 gtcaagatga ttgctgttaa aacttgcgga aaactctatt gggcaggtga atatgctatt
    19921 ttagagccag ggcagttagc tttgataaag gatattccca tctatatgag ggctgagatt
    19981 gctttttctg acagctaccg tatctattca gatatgtttg atttcgcagt ggacttaagg
    20041 cctaatcctg actacagctt gattcaagaa acgattgctt tgatgggaga cttcctcgct
    20101 gttcgcggtc agaatttaag acctttttcc ctaaaaatct gtggcaaaat ggaacgagaa
    20161 gggaaaaagt ttggtctagg ttctagtggc agcgtcgttg tcttggttgt caaggcttta
    20221 ttggctctct ataatctttc ggttgatcag gagctcttgt tcaagctgac tagcgctgtc
    20281 ttgcttaagc gaggagacaa tggttccatg ggcgaccttg cctgtattgt ggcagaggat
    20341 ttggttctct accagtcatt tgatcgccag aaggcggctg cttggttaga agaagaaaac
    20401 ttggcgacag ttctggagcg tgattgggga ttttttatct cacaagtgaa accaacttta
    20461 gaatgtgatt tcttagtggg atggaccaag gaagtggctg tatcgagtca catggtccag
    20521 caaatcaagc aaaatatcaa tcaaaatttt ttaagttcct caaaagaaac ggtggtttct
    20581 ttggtcgaag ccttggagca ggggaaagcc gaaaaagtta tcgagcaagt agaagtagcc
    20641 agcaagcttt tagaaggctt gagtacagat atttacacgc ctttgcttag acagttgaaa
    20701 gaagccagtc aagatttgca ggccgttgcc aagagtagtg gtgctggtgg tggtgactgt
    20761 ggcatcgccc tgagttttga tgcgcaatca accaaaacct taaaaaatcg ttgggccgat
    20821 ctggggattg agctcttata tcaagaaagg ataggacatg acgacaaatc gtaaggacga
    20881 gcatatcctc tatgcccttg agcagaaaag ttcctataat agctttgatg aggtggagct
    20941 gattcattct tccttgcctc tttacaatct ggatgaaatc gatctttcga cagagtttgc
    21001 tggtcgaaag tgggactttc ctttttatat caatgccatg actggtggaa gtaataaggg
    21061 aagagaaatc aatcaaaagc tggctcaggt ggcggaatcc tgtggtattt tatttgtaac
    21121 gggttcttat agcgcagccc tcaaaaatcc aacggataat tctttttctg tcaagtctag
    21181 tcatcccaat ctcctccttg gaaccaatat tggattggac aaacctgtcg agttaggact
    21241 tcagactgta gaagagatga atcctgttct attgcaagtg catgtcaatg tcatgcagga
    21301 attactcatg cccgagggag aaaggaagtt tagaagctgg caatcgcatc tagcagatta
    21361 tagcaagcaa attcccgttc ctattgtcct caaggaagtg ggctttggaa tggatgccaa
    21421 gacaatcgaa agagcctatg aattcggtgt tcgtacagtg gacctatcgg gtcgtggtgg
    21481 caccagcttt gcctatatcg aaaaccgtcg tagtggccag cgtgattacc tcaatcaatg
    21541 gggtcagtct accatgcagg cccttctcaa tgcccaagaa tggaaagata aggtcgaact
    21601 cttggttagt ggaggggttc ggaatccgct ggatatgatt aagtgcttgg tttttggtgc
    21661 taagtctgtg ggattgtcac gaaccgttct ggaattggtt gaaacctaca cagttgaaga
    21721 agtgattggc attgtccaag gctggaaagc agacctacgc ttgattatgt gttcccttaa
    21781 ctgtgccacc atagcagatc tacaaaaagt agactatctt ctttatggaa aattaaaaga
    21841 agcaaatgat cagatgaaaa aggcgtaacc agcgcctttt ttccatcctc agactgaggt
    21901 gacttttttg aattgtgata aaatagaagg gagaggatga acctatgaga aaatttaaaa
    21961 tctttttatt tatcgaagcc tgtcttctga caggagctct gattttgatg gtatcagagc
    22021 atttttcgcg ttttctgctg atactattcc tctttttgct tttgattcgc tactacactg
    22081 gtaaagaggg gaataatctt cttttagtag cggcaaccat tctcttcttt ttcattgtta
    22141 tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt tatctatagt ctctttcttc
    22201 tttacccgat gatgaaccag gaaaaagagc agaccaattt ggtttttgaa gaggttgtga
    22261 cggttaagaa ggagaaaaat cgttggtttg gaaatcttca tcatttttca agctaccaga
    22321 cttgccaatt tgatgatatc aatctctttc gcttcatggg caaggacact attcatctgg
    22381 agagagtcat cttaaccaat catgacaatg tcattatcct cagaaagatg gtaggaacga
    22441 ccaaaatcat cgtacctgta gatgtggaag tcagtctcag cgttaactgt ctctatgggg
    22501 atttgacttt tttcaaccag cccaagcgag ccctccgcaa tgaacactat catcaagaaa
    22561 caaaagacta tctcaagagt aacaagagtg tcaagatttt cttgaccact atgattggtg
    22621 atgttgaggt ggttagagga tgaaaaaaca agcctatgtc attatcgctc tcacctcctt
    22681 cctgtttgtc ttttttttct cccatagctt gctggaaata cttgattttg actggtctat
    22741 ctttttgcac gatgtcgaaa aaacagaaaa atttttcttt ttattgttgg ttttcagcat
    22801 gtccatgacc tgtctcttag ccctgttttg gcgagggatc gaagagcttt ctctaagaaa
    22861 aatgcaggct aatctcaagc gtttattggc agggcaagaa gtggttcagg ttgtagatcc
    22921 agatttggat gccagtttca agtccttatc aggtaaactt aaccttttga cagaggctct
    22981 tcaaaaagct gaaaatcata gccttgctca ggaagaggaa atcatcgaga aggaacggaa
    23041 gcgaattgct cgggatttgc acgatacagt cagtcaggag ttgtttgcgg cccacatgat
    23101 tttatcgggt atcagtcagc aggctttgaa attggataga gaaaagatgc agacccagtt
    23161 gcagagtgtc acagctattt tagaaacagc ccagaaggat ttgcgggttt tgctcttgca
    23221 tttgcgacca gttgaactgg agcagaagag cttgatagaa gggattcaaa ttcttttaaa
    23281 agagcttgag gacaagagtg atcttagggt tagtctcaag cagaatatga cgaaattgcc
    23341 taagaaaatc gaggagcata tcttccgtat cctgcaagag ttgattagca ataccctccg
    23401 ccatgcccag gcatcttgcc tagatgtcta cctctatcag acagatgttg aattgcaact
    23461 gaaggtggtg gacaatggga ttggtttcca gttagggagc ttagacgact tgagttatgg
    23521 actgcgaaat atcaaggagc gggttgaaga tatggctgga acagttcaac tcttgacagc
    23581 tcccaagcaa gggctggcgg ttgatatccg tattcctctg ttagataagg aatgataaag
    23641 gagtaaagat gaaaatttta ctagtagatg accatgaaat ggtccgattg ggcttgaaaa
    23701 gctactttga cctccaagac gatgtagaag ttgtgggtga ggcgtccaac gggtctcaag
    23761 ggattgactt ggccttggaa ctgcgtccag atgtcattgt catggatatt gtcatgcctg
    23821 agatgaatgg gattgacgcg accttagcaa tccttaaaga atggcctgaa gccaagattt
    23881 tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc agtcttagat gctggtgcca
    23941 aaggctatat gctcaagact tctagtgcag atgaattgct tcatgccgtc agtaaggtag
    24001 ctgctggcga gctggccatt gagcaagagg ttagcaagaa ggttgaatac caccgcaatc
    24061 atatggaact tcatgaagaa ttgactgcgc gtgagcgaga tgttctccaa ctcatcgcca
    24121 agggctacga aaatcagcgc atcgcagatg acctctttat ctctctcaag acggtcaaga
    24181 cccacgtgtc caatattctt gccaaacttg aagtcagcga tcgtacccag gcggctgtct
    24241 atgcctttca gcaccatttg gtggggcaag aggagtttta gatgagttta gcagatttac
    24301 ttgaggagct agaagcagca aaagactcta aaaaagcaag gtccatggaa gcctatatgc
    24361 gccatcaatt ttcttttcta ggtattgcgg tgcctgaaag aaataaactc tataaaatat
    24421 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    24481 aagaatccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    24541 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    24601 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacactc tgaactagaa
    24661 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    24721 caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgctctttg attttcattg
    24781 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    24841 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    24901 aaccaaacag aattttttat caataaagcc attggctgga ctctgcgaga ctactccaaa
    24961 acgaatccca cttgggtaac atgctttatt gagaaaaaca aggaaagaat ggctgaactt
    25021 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    25081 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    25141 ctatagtaga ttaagaaatt tagaatagta cgctataatt acattaggag gatacaataa
    25201 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    25261 gccagttatc gacagtatct gctttgagtg ttatttctag tacaggtgaa gaatatgagg
    25321 taagtgagac actagaaaaa ggtccagagt ctaatgattc ttcattatct gagatttcac
    25381 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    25441 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    25501 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    25561 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    25621 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    25681 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    25741 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    25801 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    25861 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    25921 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    25981 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    26041 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    26101 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    26161 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    26221 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    26281 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    26341 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaaatcg cactagccac
    26401 atttttcttc ggtttgttag cgacaaatac agtatttgca gatgattctg aaggatggca
    26461 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    26521 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    26581 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    26641 gattgctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    26701 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    26761 atatgatagc caagcagaga aacgagtcta ttattttgaa gatcagcgta gttatcatac
    26821 tttaaaaact ggttggattt atgaagaggg tcattggtat tatttacaga aggatggtgg
    26881 ctttgattcg cgcatcaaca gattgacggt tggagagcta gcacgtggtt gggttaagga
    26941 ttaccctctt acgtatgatg aagagaagct aaaagcagct ccatggtact atctaaatcc
    27001 agcaactggc attatgcaaa caggttggca atatctaggt aatagatggt actacctcca
    27061 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    27121 tgctgaaaat ggtgatatga gaactggctg gcaaaacctt gggaacaaat ggtactatct
    27181 ccgttcatca ggagctatgg caactggttg gtatcaggaa agttcgactt ggtactatct
    27241 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    27301 tgcctatgat tcaggtgctt tagctattaa taccacagta ggtggttact atttaaacta
    27361 taatggtgaa tgggttaagt aatgaagact aattgtaaac tgtgatggat acttaacttt
    27421 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    27481 tactgccccc caaaagttag acaaataatt tatccgaagg atttagttct gtattgcaca
    27541 gggctaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc aatatagtct
    27601 acaatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    27661 tccgatttca gaatcccaaa gaaggactcc atcataccgt tgtcttggct gtttcccttg
    27721 cgtgacatgg atgcttgaat tcccttaccc tcaagaaact gatgataaga atcgtgttga
    27781 tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc tgtgaatgcc
    27841 tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt ataggcgata
    27901 atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt acttgctgga
    27961 atggcaaatt ctgtcacatc tgtgtagcac ttttccattg ttttagagcc ttcaaattgg
    28021 ccttgaatga gattctctgc cttcttgcca acgtctcctt tatgagaaga atattttcgt
    28081 ttctgtcgca ttttagcttg taaattgagt acttttatca agccttgaac tcttttatga
    28141 tttaccagat aaccacgatt tcttagttct aaataaattc gacgataagc ataatttccc
    28201 ttgtgttcga taaaaatgga ttgaatttca gctttaagct cttggtcctt atctgttttg
    28261 tctagctgtt tcaagtgata gtagtaggtc gaacgagcta gtttaatgga ttttagaaga
    28321 agatctaacg aaaactcagt cattaattct tgaacaattt ctgtctttct tctttctctt
    28381 tttcctcctt caatcggagt tctcttaact tttttaggat ggcattctcc gctctcaggt
    28441 actcattttc tgcttgaaga tattctaatt ctgtcctctc ttcaggtctc gtttttggct
    28501 tacgtcccat tttaggtact ctccctcttg ttttctcaac aatagtatac ccgtttttcc
    28561 tgtattgtgc tagccagtta agaagtatcg tacgacttgg gaggccgtat tcaagagaaa
    28621 ctctatcttt agtcc
//
LOCUS       DBERAE010000026        27464 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.26, whole genome shotgun sequence.
ACCESSION   DBERAE010000026 DBERAE010000000
VERSION     DBERAE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.26"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(8..730)
                     /locus_tag="ACL70N_001318"
     CDS             complement(8..730)
                     /locus_tag="ACL70N_001318"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0590108.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DINTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     KPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(1043..1273)
                     /locus_tag="ACL70N_001319"
     CDS             complement(1043..1273)
                     /locus_tag="ACL70N_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS0590109.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(1283..2524)
                     /locus_tag="ACL70N_001320"
     CDS             complement(1283..2524)
                     /locus_tag="ACL70N_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGS0590110.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(2546..2698)
                     /locus_tag="ACL70N_001321"
     CDS             complement(2546..2698)
                     /locus_tag="ACL70N_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590111.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(2719..2997)
                     /locus_tag="ACL70N_001322"
     CDS             complement(2719..2997)
                     /locus_tag="ACL70N_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGS0590112.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(2990..3253)
                     /locus_tag="ACL70N_001323"
     CDS             complement(2990..3253)
                     /locus_tag="ACL70N_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGS0590113.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(3355..7746)
                     /locus_tag="ACL70N_001324"
     CDS             complement(3355..7746)
                     /locus_tag="ACL70N_001324"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGS0590114.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VDKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMASPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(7850..9931)
                     /gene="fusA"
                     /locus_tag="ACL70N_001325"
     CDS             complement(7850..9931)
                     /gene="fusA"
                     /locus_tag="ACL70N_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGS0590115.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(10356..10826)
                     /gene="rpsG"
                     /locus_tag="ACL70N_001326"
     CDS             complement(10356..10826)
                     /gene="rpsG"
                     /locus_tag="ACL70N_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGS0590116.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(10846..11259)
                     /gene="rpsL"
                     /locus_tag="ACL70N_001327"
     CDS             complement(10846..11259)
                     /gene="rpsL"
                     /locus_tag="ACL70N_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGS0590117.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            11676..15473
                     /gene="spuA"
                     /locus_tag="ACL70N_001328"
     CDS             11676..15473
                     /gene="spuA"
                     /locus_tag="ACL70N_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGS0590118.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(15573..16622)
                     /locus_tag="ACL70N_001329"
     CDS             complement(15573..16622)
                     /locus_tag="ACL70N_001329"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGS0590119.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SDGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHIPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            16679..16816
                     /locus_tag="ACL70N_001330"
     CDS             16679..16816
                     /locus_tag="ACL70N_001330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590120.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTNEVSNHTYGKATLTWFEEI
                     F"
     gene            complement(16893..18701)
                     /gene="glmS"
                     /locus_tag="ACL70N_001331"
     CDS             complement(16893..18701)
                     /gene="glmS"
                     /locus_tag="ACL70N_001331"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGS0590121.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYFEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(18894..20273)
                     /gene="bglA"
                     /locus_tag="ACL70N_001332"
     CDS             complement(18894..20273)
                     /gene="bglA"
                     /locus_tag="ACL70N_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS0590122.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(20373..22226)
                     /locus_tag="ACL70N_001333"
     CDS             complement(20373..22226)
                     /locus_tag="ACL70N_001333"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGS0590123.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(22239..23498)
                     /gene="rseP"
                     /locus_tag="ACL70N_001334"
     CDS             complement(22239..23498)
                     /gene="rseP"
                     /locus_tag="ACL70N_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGS0590124.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGGKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(23520..24323)
                     /locus_tag="ACL70N_001335"
     CDS             complement(23520..24323)
                     /locus_tag="ACL70N_001335"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGS0590125.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(24332..25090)
                     /locus_tag="ACL70N_001336"
     CDS             complement(24332..25090)
                     /locus_tag="ACL70N_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGS0590126.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(25321..25893)
                     /locus_tag="ACL70N_001337"
                     /pseudo
     CDS             complement(25321..25893)
                     /locus_tag="ACL70N_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            complement(25874..26872)
                     /gene="ruvB"
                     /locus_tag="ACL70N_001338"
     CDS             complement(25874..26872)
                     /gene="ruvB"
                     /locus_tag="ACL70N_001338"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGS0590127.1"
                     /translation="MSRILDNEMMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            27006..27098
                     /locus_tag="ACL70N_001339"
     CDS             27006..27098
                     /locus_tag="ACL70N_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS0590128.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT         7986 a         6505 c         5243 g         7730 t
ORIGIN      
        1 aactaaatta aataatatta gcgcggagaa tttctaattc ttccttggtc aagcgacgcc
       61 attcccctcg ttccaggttc tcatctaata ctaaagttcc catagtcaat cgttgcaagt
      121 ccaccacttc cttgccacag tagcccacca tacgcttgat ctgatgaaac ttcccttctg
      181 caatggtcac acggatttgg ctttgattct tttctgtatc tatggataca agctccagta
      241 tagcgggttt acaggtaaag tctttgagag gaataccctc agcaaatgtc tccacatctt
      301 cttgggtcat gattcccttg acttgtgcca gataagtctt gtccacatga cgcttgggcg
      361 aaagaagaac atgagccagc tgaccatcat tggtcaagag caaaagacca tgcgtgttaa
      421 tatccaagcg tcctactggg aaaacttcct tactccgcgc caagtcatcc aacaagtcca
      481 gaacggttct gtgcttggga tcctcagtcg ctgagataac tcctttgggc ttgttcatca
      541 tgtagtagac aaactcttca tactccaaca cttgcccatc aaagcgaatc tcatctattt
      601 tttcatcaat ctgcaattta gctgattttt cttttttacc atttacagtc acgcgcccag
      661 ccttgagcaa gtttttgacc tcagtccgac ttcccaccgc acaggcaact aaaaatttat
      721 ctaatctcat agaactatta tatcatatca aaaggaggct ggtacaatga ccaacctcct
      781 tttcgtttca tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct tgccgtatat
      841 atgttactga cttcgtcagt tctatctgca acctcaaaac agtgttttta gctgacttcg
      901 tcagttctat ctgcaacctc aaaacagtgt ttttagctga cttcgtcagt tctatctgca
      961 acctcaaagc agtgctttga gcaacctgcg gctagtttcc tagtttgctc tttgattttc
     1021 attgagtatc agatttagga aattaacttc ctcgtctcca aaaaatagct aagacaatca
     1081 tggcacctaa aacagctggg ataatagctg ttcctgataa aactggcccc caagttccaa
     1141 agagcaagtg acctagaaag gctccgatcc aaccgagaaa catttttcca aaacatccca
     1201 ttcgctctcc acgattggtc atagcacctg ctaaaaatcc cactaggaga ccaacgaaca
     1261 tacttcctaa catattatct ccttaatttg cccaattccc attacggaaa agaggtaccc
     1321 gcgttccatc ctcacgaata ccatcgatat ccatttggtt agaaccaatc ataaagtcta
     1381 cgtgaacatc tgaacggtta agccctgcag cttcaagctc ctcttcgctc atctccgctc
     1441 catcaacaag gctagtcgca taggctgcac cgatagccaa gtggtttgac gcattttcat
     1501 cgaaaagggt gttaaagaag gtaatgcctg actgagaaat tggacttgga tctggtacca
     1561 aggcacattc acccaaggca cgcgcacccg cattttcaaa gacaaggtct ttcataacct
     1621 gatcaccctt ctcagcagtg atatctacga tttgtccatc cttaaagatc accttaatgc
     1681 cttcaatgat atttccgttg tagctaagcg gttttgtaga agtgacataa ccatctgcac
     1741 gacggaagtc aggcgctgtg aagacctctt ctgtcggcat atttggcaag aatccttcgc
     1801 cctgtgcatt gacagcacca gctgattccc aaacgtggtt ctttggcaaa ccaagtgtta
     1861 aatctgttcc tggcgctgtg tagtgaaggg ctgaaaattg ctccttatta agcatatcgg
     1921 ccttgctctt gagaatggct gcatgctctt cccaggcctt aacaggatct gcttcgtaga
     1981 cacggcaagt tttgaagatt tggtcccaaa ggagatcgac tgcttcttcg tcgctcgcag
     2041 catttgggaa gactttctta gcccactcaa gtccagcagc ggctgctaca gtccagctaa
     2101 ccttgttaga ttgagttgcg attcgcattg gcttcatggc aagtcccata gctttagcag
     2161 aagctgaaag cttgtcagcg tccactccgt tcaaggcacc tggatcagat gaacgaactc
     2221 caagacggct agccttgttc tccaagagat agttcatctc agcaatcttg tattctggca
     2281 cattgtccaa acgctccatc ggggcatgga ggaatttctc acggttaatc acatcatctg
     2341 tccactgaac gatgacctca tgcgcaccca aggcataagc ttctttcacg attagatgtg
     2401 ccaattcacg ttgctccaca tcaatagaga gagccaaagt gtgaccaggt tgcacgttaa
     2461 ttccgttcgc aaccaacaat ttcgcatatt tttctagatt ttctttaaaa tttggtaaaa
     2521 ccatcctgtt ttctcttttc tatttttatt tttctttcaa agcagaaaag attcctgcta
     2581 aagcaatagc acctgacaag agtgctgtcg ataaaagaat tgtacgatca gcaagttcta
     2641 attgatattc aaataccttc ttagccggct tatcttccgc aaatattctt agtttcatga
     2701 gaaccccctt aaaatagatt aaaataaatc actgtgactg cctgtcctca gcaaatttaa
     2761 aatcaattcc gacttatcta ctttataaac caaaagccaa tctggctggg tatggcattc
     2821 acgaactcct tgaaaatgct tggatgccgt caatgaatga tcacgatatc tggcaggatg
     2881 ttctttttct tgaaccagaa aattcaaaac ttcttctaat aattctgcct tcaaaccacg
     2941 cttcatagcc aacttaaaat cttttttaaa ctgtttatga taacgaatct taagcacgta
     3001 agtcctccat caaatctgag actgattcaa aagactggct catattacga ttttggtcta
     3061 aatccgttaa cacttggagc aacttccgat tttcgtctag tctaacatca aaaggtaatc
     3121 cctgatattg aattgcctga cgaaggaaaa tattaatagc tgttgtcata tccattccca
     3181 gattactaaa cacctgttgg gcctgctcct taacctcact atccagacgg atgctcatac
     3241 tcatctttga catactctca ccctctttcc atagactatt ttaacaaaaa agaaagctaa
     3301 tgtaaatcta ttggatatac gttagcctct tctaatagat tattaagcaa ttttttaaaa
     3361 caactcatca aacaaactca actggttatc ctctggcata tttccaagaa tacccatctc
     3421 atccatcttt tcaaccaagg ttgatgagag tccaccacgc ttgcgtagtt ctgttttaga
     3481 gaggaattct ccctcttcac gcgcccgcac cagttgcttg gcaacgttct ctcccagacc
     3541 atccattgct acaaatggtg ggataagggt atccccgtcg atgaggaact ctgtcgcctg
     3601 actacggtag agatctaatt tgccaaactt gaaacctcgt tcccacatct cattgacaat
     3661 ctcaagagtt gtatagagat cgatttccac attagaggct tcattgttct tccgtttttc
     3721 agagatttct tccattctgc gcttgatggc ctccaagccc gcacccatgg tcttgatatc
     3781 aaaagcctta gcacgaatgg agaagtaagc acagtagtaa taaataggat ggtgaacctt
     3841 gaagtaagct acacgcaagg ccatcataac gtaggctgcc gcatgggcct tagggaacat
     3901 gtacttaatt ttcccacagg attcgatata ccactctggc accttattag ccttcatggc
     3961 ttcgatatag ccatttctct cctcttctga aatctttagc cacaaaccct tacgtacccg
     4021 ttccataatg gtaaaggcca tcttaggttc cagacccgca tgcatgaggt aaaccatgat
     4081 gtcgtcccga caaccgataa cagtcgatag gtccgctatt ccttgcttaa tcagatcctg
     4141 agcattcccc aaccaaacgt cagtaccgtg ggacagacca gacagctgaa gcaattccgc
     4201 aaaggttgtc ggatgggttt cgtctaccat tccacgtacg aaatttgttc caaactctgg
     4261 aatccccaac atacccgtag gcgttccaat ttgttcaggt gttaccccta gcacatcagt
     4321 cccagaaaag agtgccatca cgccttcgtc atccatagga atttcattag ggtcaatacc
     4381 agacaaatcc tgaagttttc gaatcatggt cggatcatca tgtcccagta catcgagttt
     4441 gaggacgttc tcatcgatat cgtggaagtt aaagtgagtg gtctgccatt cagccgtgac
     4501 atcatctgct ggatactgga caggcgtaaa atcgtagaca tccatgtagt tcggaataac
     4561 aacgattccc cccgggtgtt ggcctgttgt ccgcttgaca cccgccgctc cttgagcgag
     4621 gcgttctact tctgcatcac gataaaactt gccataatct cgctcgtaac ccttgacaaa
     4681 tccataggca gtcttggcag ctaccgtacc aaccgttccc gcacggaagg catattcttc
     4741 accaaagata tcacgcacat ccaagtgggc gctaggctga tcttctcccg agaagttcaa
     4801 gtcaatatca ggaaccttat ccccatcaaa gccaaggaag gtctcaaacg gaatatcctg
     4861 tccgttttta ctgagtttgt gaccacagtt tggacagtcc ttatggggca tatcaaatcc
     4921 tgaaccgtac gaaccatctg tgataaactc actgtactga cactgaccac agacatagtg
     4981 aggagagaga ggattgacct ccgtaatccc aatcatggtc gcaacgaaac tagatccgac
     5041 agacccacga gaaccaacca aataaccccg ttcattagaa cgttgcacca gcatctgcga
     5101 tgccagataa atcacagcaa atccattccc cagtatggat gttaattctt tttcaatccg
     5161 caaatcaaca atatctggca gcggatttcc ataaatctca aaagctttct tataggtcaa
     5221 ctcagcaact gtttcttcag ccttgtcgat gaaaggcgta tacaagtcac ccttaacgac
     5281 ttcaacgggt tcaaatattt ctgccaaggc attagtgttt tcaataacca gtttacgagc
     5341 cagttcctct cccaaaaagg caaattcatc caacatctca ttagtcgttc gaaaatgagc
     5401 ctttggaagt ggtgctggtt gggcatgttc accatgaccg atagttcgat taatcatcgc
     5461 accctgtccc aaactacgga caataatttc acgataaatc tcttcttccg gttcgatata
     5521 gtgaacattt cccgtagcca gaacaggctt gccaaggcga tctccaacct ctatcaaact
     5581 cttgataatg gtctggagtt cctccatatc cttgacctgc tctttggcaa tcaagggcgc
     5641 atagatagcc ggtggcatga cctcgataaa gtcataatac ttggccacct caaccgcccc
     5701 atccacacct tgagaaacga ccacgtcaaa aacttcaccc tctgaacagg ctgaacctaa
     5761 aatcaagccc tctcgatggg catctagaac cgttctcgga atccgtggca ctccttcaaa
     5821 atacttggta ttagacaagg aaaccagctt aaagatattt tttagaccta cctgattctt
     5881 gacatagatg gtcgcatgct tgatccgagc ttttttgtaa gaatctggac tgattagatc
     5941 aatgttgagt ctagctaaat cggtcacacc atgtttttct gctacctctt tgataaagat
     6001 gaaaagcaga cgaccagtcg cttccgcatc gtaattggcc atgtggtgat gttccaaggc
     6061 cacaccaaaa cgcttggtca aaggccccaa accatggcgt ttatactcag gatagaggtt
     6121 tctagcaaac tccagcgtat caataactgg ctgactaatc tttggaagac catgacgctc
     6181 ataattagca ttcataaagc caacgtcaaa ggtagcattg tgggcaacta ggaccgtatc
     6241 cttgcaaaat tcttggaatt cttgcaaaac ttgttctagt ggtttggcat ttttgacatg
     6301 atcatctgta attccagtta actctgtagt aaaggctgac aagggatgcc caggattgat
     6361 aaattcatca aattcagcaa taacattccc cttgtacatc ttagaggccg caacctgaat
     6421 caagtcatta tagatagctg aaagtcccgt cgtttccacg tcaaagacca cgtaggttgc
     6481 ttctgacaag tccatctcca cttcgttata gacgataggg acacggtcct ccacgatatt
     6541 ggcttccatc ccatagatca gctggattcc cgctttctta gccgccttat agccatgtgg
     6601 aaaggactgg acattcccat ggtccgtgat agcaaccgcc ttgtgtcccc acttagcagc
     6661 tgttgcaaca atctcttcga cctctggcaa agcatccata gtcgacatgt tagtatgagc
     6721 atgaaactca acccgacgct caccttctgg catcaaatcc ttccgctcat agtgaacaac
     6781 ttcctgcaga tcctgtacgt tcatagtcaa atcgcgtgtg aagttattca tctccacatt
     6841 ccctcgaact cggagccaag aattcttctt gatgagatca aacttctggg cctcttcctc
     6901 gtttttaacc cacttttgca tagaaaaact tgaagtgtag tccgtcattt taaagttgat
     6961 taaaacacga cctgttctag tcactttttg ctccacatca aaaacaaccc cttcaaatac
     7021 cagacgattt tcctctgtcg tcacttcgat cataggagta atctccgcct tatccagctt
     7081 gggtttagct gcagcttttt tcgcttgaaa atcaaagact ggtttctctt ccgctggagg
     7141 agatgccatc tgctccagtt gttccatagc acggagcgct tcctcattgg cagcttgaac
     7201 aatctgctca ttttcagcat gaaaggcctc ttcctgctct tgggtcagga catcattctt
     7261 atcgacttga cagttaaaag ttggaaaacc aaacttttca agttgtttgg ctaaattagg
     7321 aagatgattc ttcttaaaat gttccttatc aatcgcctca gatccttcaa taaatagctg
     7381 attaccctca gcacgaactt gcaaattttg ataaagggac ttaaaacctt gactagcaca
     7441 tggaccttca gagaaagcct ccctatagta ggactgcaag agctgatttg aaaattcttg
     7501 agaccgagcc ttaatttcaa aaacagcttt attgcctgtc ttagaaaatt cttcgctcaa
     7561 acctttcttt aattctaaaa agatttcaat cggtaaaata ttagaaaata cgaaatgaaa
     7621 ctcccatacc ttactaattt tatgaaccac aactcgctca atattggcct gtgctaaagc
     7681 aggagcctgt ctcatttcag caggcatccc caattgattc atcaaaattt caaaactatt
     7741 tgacattcat tttcctcaca ttattcttct actattttac catatttaga ggtattttct
     7801 aaagacaaaa ggaagccact aagtgacttc cttctagagt gaggacggat tagtcttcac
     7861 ctttattttt cttaataatt tcttcttgta ctgacttagg tacatcttcg tagtggtcaa
     7921 ataccatcat gaatgtacca cgtccttgag atgcagaacg aagaactgtt gcgtaaccga
     7981 acatttcagc aagtggaacg taagcacgaa cgatttggct gttaccgtgt gcttccatac
     8041 catctacacg tccacgacga gcagttacgt gacccataac atcaccaagg ttttcttctg
     8101 gaacagtgat tgttacaagc atcattggtt caaggatagc tggttgtgct gatttagcag
     8161 cttctttaag ggaaagtgaa gccgcaatct tgaaggcagt ttcagatgag tcgacatcgt
     8221 gatatgaacc atcataaagc ttagctttaa cgtcaaccat tgggtaacct gcaagaacac
     8281 cgttagccat agattctacc aaaccttttt caaccgctgg gataaattca cgaggaacca
     8341 caccaccgac gattgcgttt tcgaattcga atcctttacc ttcttcgttt ggagtaaatt
     8401 caatccacac atcaccgaat tgacctttac caccagactg acgtttgaag aatccacgtg
     8461 cttgagtaga agcgcggaat gtttcacggt aagatacttg aggcgcacct acgttcgctt
     8521 caactttgaa ctcacgacgc atacgatcaa caaggacgtc aaggtgaagt tcacccatac
     8581 ctgagataac tgtttcacca gtttcaacgt ttgtttcaac gcggaatgtt ggatcttctt
     8641 cagccaattt ttgaagggcg atacccatct tgtcttggtc agctttagat tttggctcaa
     8701 ccatcaattg gataactggt tctggaacgt tgattgactc aaggatgatt ttagattttt
     8761 catctgtcaa tgagtcacca gttgtagtat ctttcaaacc aacggcagca gcgatatcac
     8821 ctgagtaaac agtgtcgatt tcttgacggc tgttagcgtg catttgaagg atacgtccga
     8881 tacgttcacg tttaccttta gaagtattca atacgtatga acctgattga agaacacctg
     8941 agtaaacacg gaagaatgtc aaacgaccta cgaatgggtc agtcatgatc ttgaaggcaa
     9001 gagctgcaaa tggctcttcg tcagatgctg gacgagtttc ttcagcgtct gtatctgggt
     9061 taataccttt gattgctggg atgtcaagtg gacttggaag gtagtcgata accgcatcaa
     9121 gcatcaattg aacacctttg tttttgaagg ctgaaccaca caatactggg aagaattcaa
     9181 cgttgatagt cgctttacgg ataccagctt tcaattcttc gttagtgatt tcttcacctt
     9241 cgaggtattt catcatcaat tcttcgtcag tttcagcaac tgcttcaatc aatttttcac
     9301 ggtattcttg agcttggtca aggtattcag ctgggatgtc ttcttcaagg atatccgtac
     9361 caaggtcgtt agtatagatt tcagctttca tcttgattaa gtcaatgata ccacggaagt
     9421 catcttcaga accgattggc aattggattg ggtgtgcatt tgcttgaagg cgatcgtgaa
     9481 gtgtgcttac agagtaaagg aagtcagcac cgattttgtc cattttgttg gcaaatacga
     9541 tacgtggaac tccgtactca gttgcttgac gccaaactgt ttcagtttga ggctcaacac
     9601 ctgattgtga gtcaagaacg gtaaccgcac catccaatac acgaagagaa cgttgtactt
     9661 cgattgtgaa gtccacgtgt cctggtgtgt cgatgatgtt tacgcggtgg ttgttccatt
     9721 gagctgttgt cgcagcagat gtgatcgtga taccacgttc ttgctcttgc tccatccagt
     9781 ccatttgtga cgcaccttcg tgagtttcac cgattttgtg gattttacca gtgtagtaaa
     9841 gaatacgctc agtagttgtt gttttaccgg catcgacgtg agccatgata ccgatattac
     9901 gagttttttc aagtgaaaat tcgcgtgcca tgaggtttgt ttctcctatt tatttttgat
     9961 ttctattcta ttataacacg attttaataa aaacggatag gcaggaccta cccgttctca
    10021 atgttttcat gctattgttg gtttcaactt acgagatggt aagctgagtt atagctaata
    10081 ctaatcgatt tagctaattt gaacccgggc taaagttagt tagccgatgt gagctggaac
    10141 gggatgctgc gtgaaaaaga taaaactcct tgtattcgtc gaatactgcg tcagtttcct
    10201 attttcacct tgcatcctta ccgttcctag catcatgatt tagttgagct caagctaaaa
    10261 gtctggagaa aaagatgaat ctcattggtt gcaaccgcaa cctgcttcga ttccctattt
    10321 tctctgggac tttcttaacg ctttcgcatc ctatcttacc aacggaagtg tgcgaatgca
    10381 cggttagctt cagccatacg gtgagtatct tcacgtttct taactgctgc accagtgttg
    10441 ttagcagcat ccaagatttc ttttgcaaga cggtcttgca ttgtgtgttc accacgaaga
    10501 cgagcgattg ttaccaacca acgaagtcca agtgttgtac gacgttctgg acgaacttca
    10561 actgggactt ggtagttaga accaccaaca cgacgtgcac gtacttcaag tacaggcatg
    10621 atgttttcca tagctgtttc aaatacttca agtgcatcgt tgccagtagc ttctttgatt
    10681 tgctcaaaag caccgtaaac gattgaagca gcagtaccac gtttaccatc aagcataacg
    10741 cggttgataa gacgagtaac tagttgtgaa ttgtatagcg gatctggcaa tacgtcacgt
    10801 tttggagctc tatttttacg actcatttct ctttatcccc tttccttatg cttttggacg
    10861 tttagtaccg tatttagaac gaccttgttt acgatcgtta acacctgcag tatcaagtgc
    10921 accacggacg atatggtaac gtacccctgg aaggtctttt acacgtccac cgcgaagaag
    10981 caccacgctg tgctcttgca agttgtgtcc gatacctggg atgtaggcag taacttcgat
    11041 aaggttgctc aaacgtacac gagcgaattt acgaagggct gagttaggtt ttttaggtgt
    11101 cattgttcca acacgagttg caacaccacg tttttgtggt gaagaaacgt ttgtttgaac
    11161 ttttttatga ctattgtaac caacgttcaa agctggtgat ttagattttt ctacttttga
    11221 tttacgcggt ttgcgaacca attggttaat tgtaggcatc tacattctcc tgtgtttttt
    11281 tatttttggt gatgatacac ttggtgacag atatcatctg tgtgtacttt tgcaacattt
    11341 gtcagcacgt ccctgtacac tcttgagaga ccaaaagtaa aaagtaccgt ctattattgt
    11401 aacaaaattt tcccttgttt gtcaagatat ttttcttttt tattggtaat gttagagatc
    11461 aatttctgaa taaaaatagc tgggaacaca tcatcttcct aataatacgg cttggcttat
    11521 gtgacatttt tatctccgtc atttatactg atatataaaa tagtacagaa aacttctcaa
    11581 aagtaagaat ttttttcaca aatcaaagaa aacgcttgca tattgtttta ctacatgcta
    11641 tactgatata gaaatttatt gattggagaa tcattatgag aaaaacacca tctcacactg
    11701 agaaaaaaat ggtctacagc atccgttccc tcaaaaatgg aactggttct gtccttatcg
    11761 gcgcaagcct tgtcttgctt gccatggcta caccaactat ctcatccgac gaaagtacac
    11821 caaccactaa cgaacccaac aacagaaata caaccaccct tgcccaacct cttactgata
    11881 cagcagctgg ctctggtaag aacgaaagtg atatttcttc acctagaaat gcaaacgctt
    11941 ccctagagaa aacagaagaa aaacctgcaa cagagccaac tacttctact agtccagtaa
    12001 caactgaaac taaggcagaa gagcccatcg aagataacta cttccgtatc catgtcaaaa
    12061 aacttcctga agaaaacaag gatgctcaag gactatggac ttgggacgat gttgaaaaac
    12121 catctgaaaa ctggccaaac ggagctttgt ccttcaagga tgccaagaaa gatgactacg
    12181 gctattacct agatgtcaaa ttaaagggag aacaagccaa gaaaattagc ttcctcatca
    12241 acaatacagc tggaaaaaat ctaaccggcg ataaatctgt agaaaaacta gttccaaaaa
    12301 tgaacgaggc ttggttagac caagattaca aggttttctc ttacgagcca cagcctgcag
    12361 gaactgttcg cgtcaactac taccgcacag atggcaacta tgacaagaaa tctctctggt
    12421 actggggaga tgtgaaaaat ccaagtagcg ctcaatggcc tgacggaaca gactttacgg
    12481 ctacaggcaa atatggccgc tatatcgaca ttcctcttaa tgaagccgca agagaatttg
    12541 gatttttatt actagatgag agcaaacaag gagacgacgt gaaaatccgt aaagaaaatt
    12601 ataagttcac agatttgaaa aatcatagcc aaattttcct aaaagacgat gatgaatcga
    12661 tttacacaaa tccatactat gtccatgata tccgtatgac aggagcccaa cacgtaggca
    12721 cttctagcat tgaaagtagc ttttcaacac ttgtcggtgc taaaaaagaa gatatcctca
    12781 aacactccaa catcactaat cacctaggaa acaaggtaac tattaccgat gttgcaatcg
    12841 atgaagctgg taagaaagtg acctacagcg gagatttctc tgacacaaaa catccttata
    12901 ctgttagcta caattccgac caattcacta ccaaaacaag ctggcacctg aaagatgaga
    12961 catacagcta tgatggcaaa ctgggagctg acctaaaaga agaaggaaaa caagttgatt
    13021 tgaccctttg gtcaccaagt gctgataagg tttctgttgt tgtctacgac aagaatgacc
    13081 ctgacaaagt agttggaact gtcgctctcg aaaaagggga aagaggaact tggaaacaaa
    13141 ctctagacag cacaaacaaa ctcggaatca cagatttcac tggctactat tatcaatacc
    13201 aaatcgagcg tcaaggtaaa actgttcttg cactcgatcc ttacgctaaa tctcttgctg
    13261 cttggaatag cgacgatgcc aagattgacg atgcccataa agtggctaaa gccgcctttg
    13321 tagatccagc taaactcgga cctcaagact tgacttatgg taagattcac aatttcaaga
    13381 ctcgtgaaga cgccgttatc tacgaagctc atgtgcgtga cttcacttca gatcctgcca
    13441 ttgcaaaaga cttgaccaaa ccatttggga cttttgaagc cttcattgaa aaactagact
    13501 atctcaaaga cttgggtgta acccatatcc agctccttcc agtcttgtct tactactttg
    13561 tcaatgaatt gaaaaaccat gaacgcttgt ctgactatgc ttcaagcaac agcaactaca
    13621 actggggata tgaccctcaa aactacttct ccttgactgg tatgtactca agcgatccta
    13681 agaatccaga aaaacgaatc gcagaattta aaaacctcat caacgaaatc cacaaacgtg
    13741 gtatgggagc tatcctagat gtcgtttata accacacagc caaagtcgat atctttgaag
    13801 acctagagcc aaactactac cactttatgg atgccgatgg cacacctcga actagctttg
    13861 gtggtggacg cttggggaca acccaccata tgaccaaacg gctcctagtt gactctatca
    13921 aatacctagt tgatacctac aaagtggatg gcttccgctt cgatatgatg ggagaccatg
    13981 acgccgcttc tatcgaagaa gcttacaagg ctgcacgcgc cctcaatcca aacctcatca
    14041 tgcttggtga aggttggaga acctatgccg gtgatgaaaa catgcctact aaagctgctg
    14101 accaagattg gatgaaacat accgatactg tcgctgtctt ttcagatgac atccgtaaca
    14161 acctcaaatc tggttatcca aacgaaggtc aacctgcctt tatcacaggt ggcaagcgtg
    14221 atgtcaacac catctttaaa aatctcattg ctcaaccaac taactttgaa gctgacagcc
    14281 ctggagatgt catccaatac atagcagccc atgataactt gaccctcttt gacatcattg
    14341 cccagtctat caaaaaagac ccaagcaagg ctgagaacta tgctgaaatc caccgtcgtt
    14401 tacgacttgg aaatctcatg gtcttgacag ctcaaggaac tccatttatc cactccggtc
    14461 aggaatatgg acgtactaaa caattccgtg acccagccta caagactcca gtagcagagg
    14521 ataaggttcc aaacaaatct cacttgttgc gtgataagga cggcaaccca tttgactatc
    14581 cttacttcat ccatgattct tacgattcta gcgacgcagt caacaagttt gactggacta
    14641 aggctacaga tggtaaagct tatcctgaaa atgtcaagag ccgtgactat atgaaaggtt
    14701 tgattgccct tcgtcaatct acagatgcct tccgacttaa gagtctccaa gatatcaaag
    14761 accgtgtcca cctcatcact gtcccaggcc aaaatggtgt ggaaaaagag gatgtagtga
    14821 ttggctacca aatcactgct ccaaacggcg atatctacgc agtctttgtc aatgcggatg
    14881 aaaaagctcg cgaatttaat ttgggaactg cctttgcaca tctaagaaat gcggaagttt
    14941 tggcagatga aaaccaagca ggatcagtcg gaattgccaa cccgaaagga cttgaatgga
    15001 ctgaaaaagg cttgaaattg aatgccctta cagctactgt tcttcgagtc tctcaaaatg
    15061 gaactagcca tgagtcaact gcagaagaga aaccagactc aaccccttcc aagcctgaac
    15121 atcaaaatga agcttctcac cctgcacatc aagacctagc tccagaagct agacctgatt
    15181 ctactaaacc agatgccaaa gtagctgatg cggaaaataa acctagccaa gctacagctg
    15241 attcacaagc tgaacaacca gcacaagaag cacaagcatc atctgtaaaa gaagcggttc
    15301 gaaacgaatc ggtagaaaac tctagcaagg aaaatatacc tgcaacccca gatagacaag
    15361 ctgaacttcc aaatacagga atcaaaaacg aaaacaaact cctatttgca ggaatcagcc
    15421 tccttgcgct ccttggtctc ggtttcttac taaaaaataa aaaagagaac taaactagcc
    15481 ctcctataga aaaatccccc aagcattata gctcggggga ttaattttcg tacaatattt
    15541 gttgtcctaa taaacttgat taggattttt tattaagcct ctttcatagc aaaataagct
    15601 cgtacttttg gtgcaacttg tgttccgaag agttcaatag ctctcagaac ctggtcatga
    15661 ggcatagaac caagcggtat atgaagcatg aagcggtcca atcctaaatc ctctatcatg
    15721 cgaatcaatt tttcggccac ctgatctgga ttgccaacaa acatggcgcc atttggccct
    15781 acctgctcca aatattgctc ataacgcaat tcctgccagt gcggacggtc tttggaaata
    15841 gcatccacca cttgcttagt cggatggaaa taatctttca ccgcctgctc accatcttcc
    15901 gcaatccacc cccaagaatg ggctcccact ttcaagtctt tgtcagcatg gcccgcttcg
    15961 cttccaatct cacgataagc ctgaatcaac tttttaaaat aacgtggatt accaccaata
    16021 atagcatata caatcggtag accagcctga gcaatcttca ctgttgattc gacatgacca
    16081 cctgtagcta tccacaaggg caatttgtcc tgaactggac gaggataaac ttctttacca
    16141 gcaatcgttt gagtcaatcg accttgccag tctaacttgg tcttttcatt gactaactga
    16201 agcaagtcta atttctcatc aaaaagagag tcgtagtctt tcaagtcata accaaacaga
    16261 gggaaagatt ccgtgaaaga gccccttcca gccataatct ccgatcgtcc atctgacaaa
    16321 gcatcgatag tggcatactg ttggaacaaa cgaatcgggt ccatgcttga cagaatgctg
    16381 actgcactgg tcaaacggat tttcttggta ttgactgccc cagcggccag gacaatctct
    16441 ggggctgata ctgcaaaatc cgcccgatgg tgctcgccaa tcccatatac gtccaaacca
    16501 accttgtcag ccagctcaat ctctgccacc aactggcgaa tgcgttcagc atgactgtaa
    16561 gtttgtccag tcccttcaag ctccgttatt tccccaaatg ttgaaattcc caattctacc
    16621 attgtgattc tccttgtcta tctctgtact tcaatttgaa aaattattct aatactcaat
    16681 gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacagt gttttgaggt
    16741 tgtggataga actaacgaag tcagtaacca tacctacggc aaggcgacgt tgacgtggtt
    16801 tgaagagatt ttctaagagt ataacacgaa tcttgagtac aagcaaccaa tttgctcaca
    16861 agaaaaagcc tagataacta gactttttta gcttattcta ccgttactga cttggcaagg
    16921 ttacgtggtt tgtccacatc gaggccacgg tggagggttg caaagtaagc gactaattgc
    16981 gtcggtacga ccattgaaat tggtgagagg tatggatgta cggtcgtaag gacgatatcg
    17041 tcggtatctt tggctacatt ctcttctgcg atagtgagga ctttggcacc acgggctgcg
    17101 acctcttgga tatttccacg agtatggttg gcaagaactg gatctgacaa gagagccaaa
    17161 acaggcgttc cttcttcaat caaggcaatg gttccgtgct tgagttctcc tgccgcaaaa
    17221 ccttcacact ggatataaga aatctctttg agtttgagac ttgcttccat ggctacgtag
    17281 taatcttgac cacgtccgat gtaaaaggcg ttacgagttg tttcaagaag ttcacgaacc
    17341 ttggcttcaa tggtttcttt ctctgaaaga gttgattcga tagactgagc tacgattgac
    17401 aattcatgaa ccaggtcaaa ggcttgcgct ttagcattac catttgcttc tccgactgct
    17461 tttgcaagga aggcaagggc tgcgatttgc gctgtatagg ctttagttga tgccacggca
    17521 atttcaggac ctgcgtgaag gagcatggta tagttggctt cacgtgagag ggttgaacct
    17581 ggaacgtttg tcactgttaa gcttggaatt cccatttcat tagccttgac caaaacttga
    17641 cgactatccg ctgtttcacc agattggctg ataaagatga agagtggttt cttgctgaga
    17701 agtggcatac cgtagcccca ctcagatgag attccaagtt caactggtgt atctgtcaat
    17761 tcttccaaca ttttcttaga agcaaatcct gcatggtaag atgttccagc tgcaaggatg
    17821 tagatgcggt ctgcgtcttg aacagcctta atgatatctg ggtctacgac aacttgacca
    17881 gcctcatctg tgtaggcttg gatgagtttc cgcataacag ttggttgctc gtcaatttcc
    17941 ttgagcatat agtaagggta agttccctta ccgatatctg acaagtcaag ttcagcagtg
    18001 tagctagcac gctcacgacg atttccatca tagtcttgaa cttccacact atcagccttg
    18061 acgattacca actcttggtc atggatttcc atgtattggt tagtttcacg aatcatagcc
    18121 atggcgtctg agcagaccat gttatagcct tctccaagac caatcaaaag tggtgattta
    18181 tttttagcta cgtagatgac ttcaggatct tgtgagtcaa ccaaggcaaa ggcataagaa
    18241 ccacggatga tgtgaagggc ttttttgaag gcttcaagaa ctgagagccc ttcttcttcc
    18301 gcaaattttc caatcaaatg aacggctatt tcagtatctg tctgcccctt gaagtggtga
    18361 cctgcaaggt attcttcctt gatttcaaag tagttctcaa tcaccccatt atgcaccaag
    18421 acaaaacgtt ctgtctcaga gcggtgtggg tgagcattgt cctcagttgg ttttccgtga
    18481 gtagcccaac gagtatgtcc gataccagtt gttccctcaa caccagctgt cttggcagac
    18541 aattctgcaa tacgaccaac agccttcacc aaatggttat cagcaccatc taggacaaaa
    18601 attcccgcag aatcatagcc acggtattca agcttttcaa gcccttgaat caaaatatca
    18661 gttgcatttg tgtttccaac aacaccaaca attccacaca tagtatatac gacacaggca
    18721 agctgtgctt tctccttaaa attggtatag tctaattcat cttttataga atcagcaaaa
    18781 acagtatata cttgtttctt tcacttgtca agagtaaaaa ttggtatagt tcaaattaag
    18841 ctcctgtaag cataaaaact ctgaccgatt gggataatca gtcagagtcc tttttaaaat
    18901 ccattattat cgcttaattc tttgaaccag tggcctgatt tcttcagacg acgttcttgc
    18961 gtttccaagt ctaattcgac caaaccatag cgatttttat agctgttgag ccatgaccag
    19021 cagtcaataa aggtccaaat caagtagccc ttacagttgg caccatcttc aatggcacgg
    19081 tgaagttcac gaagatgacc ttttacaaag tcaatacggt aatcatcttg aatcattcca
    19141 tcttgacgga atttttcttc cccttcaaca cccataccat tctcagtcaa catccactca
    19201 atattgccat aattttcctt gatattttgg gcgatgtcat aaatcccttg ctcataaatc
    19261 tcccaaccac ggtgagaatt gattttacgt ccaggcatca cataaggctc gtaaaaatgt
    19321 tctggtaaga gtggactatc tggatgctta gcaaatcgag gagccataac acgcaaaggt
    19381 tgatagtagt tcacaccaag gaagtccacc gtattatcac gaatgagttc caactcttcc
    19441 tctgtagcat caggtaaaag accgtgttca tgcaagattt ctaccaactc ctgtggataa
    19501 gtccccaaga cagatggatc taagaaagat tgggcctgaa aaagggccgc aatacgagct
    19561 gccttgacat cagcaggatg ctggctacgt ggataagccg gtgtcaagtt gaggacaatc
    19621 ccaatcttgg aatcaggcaa aagttcatgg caagccttaa cagcccggct gctggccaat
    19681 tgtgtatgat aggctacctt aacagctgcc tctgcatcca ccttatgtgg ataatgggca
    19741 tcataaaaat aaccaaattc tacaggaacg atgggctcgt taaaggtaat ccattgatcc
    19801 actaaatctc cataagtctc aaaacaaaaa cgagcatagt cttcataggc tgagactgtc
    19861 gccttatttt cccaaccatc accatcctct tgaagggcaa aaggtaaatc aaaatgatag
    19921 agattgacta acagacgaat tcctttagcc ttaatagcct caaagacctt acgataaaaa
    19981 tccacacctt gagggttgac tttcccacag ccttgtggaa aaatccgtga ccactgaata
    20041 gaagtccgaa agactgtgtg accagtctct aacaaaagct caatatcccg ctcccaattt
    20101 tcataaaaag tcgatgtctt atctgaacca atcccattat agtaacgatt tggctccact
    20161 tggaaccagt aatcccagag attgtctccc ttaccgtcac cagctacacg tccttctgtc
    20221 tgcggtccag aagtagagga tccccagaca aaatcctttg gaaatcttag cataacattt
    20281 acctctttat ctactcattt ctcccattat acagaaaaaa caaggtaaaa actagttaca
    20341 ttttttcctt gtttttcttc tgattatagt ttttatttct tgcttaggat ttcaagcgtt
    20401 tcaagcacgt tatctgcatg aacctcaatg gtgtcaccag ttgccttgat cttaacttct
    20461 acaatgccat cggccgcttt tttaccaaca gtgatacgga ttggaagacc aatcaagtca
    20521 ctatcgctaa atttaacacc gacacgttcg ttacggtcat ctgtcaagac ttcataacca
    20581 gctcccatca agcttgcttc aagtttttct gtcaaggctt gcgcttcttc atccttgaca
    20641 ttaacagtaa tcaaatgcac atcaaatggt gccaattctt tagggaaatt gattccccaa
    20701 gcgtaacggt attcaccttt tggcgttttg ttaacaaaga ggcgagcgtg ttgctccatc
    20761 actgctgaaa gaagacggct gacaccgata ccgtaacatc ccatgatgat tggcacagca
    20821 cgaccatttt catccaagac atctgctccc atgcttgctg aatagcgagt tccgagtttg
    20881 aaaatatgac cgatctcaat accacgcgca aagttaagga caccttgtcc atctggggaa
    20941 atttcaccct cacgaacttc acggatatcc acatattctg cagtaaaatc acggcctggg
    21001 ttcacaccag tcaagtggta gccatcttcg ttagcaccga caactgcatt gcgaacatct
    21061 tgcaccttac gatctgcaat aattttaata ttctctggca aaccaactgg tccaagtgaa
    21121 ccaaatcctg cttgaacaac attcgccact tcttcttcgc tagcaacgtc aaagaaatct
    21181 gctcccaagt gatttttcaa cttgacttcg ttgagttggt catttccaac tagaagggct
    21241 gcaacaagct caccatctgc aatgtagaag agggttttaa tcgtttgttc ttctggaaca
    21301 ttgaggaaag ctgcaacttc atcaattgat ttaacatctg gcgttgcaac acgagtaact
    21361 tcttcttcag cgacaacacg gttgcttggt ttgtactcgt ttgttgccat ttctaagtta
    21421 gctgcatagc tagactcact tgagtaagca atggtatctt caccagagac tatccatttg
    21481 agcaattctg ccttgatttc ttcttgcact tctgcaggaa tttcgtcaaa tgaggcaact
    21541 gacttgtcca agacaaccca gcggtcaagg tctgtacgag cagatgtaat ggccataaat
    21601 tcttggctat ccttaccacc catggctcca ccgtcaccaa taatagcctt gaagtctaaa
    21661 ccactacgag tgaaaatacg ctcataagct gctttgtact catcataaac actatccaaa
    21721 ctatcatagt tagcgtggaa actataagca tccttcatga taaactcacg tgtacgaaga
    21781 agtccattac gcgggcgttt ttcatcacga tacttgggct gaatttgata aaggttgagt
    21841 ggcaattgct tgtaagattt aacagaatca cggacaatag ctgtaaaggt ttcttcgtga
    21901 gttggaccta agataaagtc tgatttttca cggtttttta gtttgtaaag gtcttcacca
    21961 taggtttcgt aacgacctga ttcacgccac aattctgcac taagaagggc tggagccaac
    22021 atctcaacag caccaatctt ttcgaattct tggcgcatga tgtttttagc tttttcaatc
    22081 acacggttgg caagtggtag ataagaataa acacctgctg aaacttggcg aacataacca
    22141 gcacgcaaca taagagcatg gctgataact tgagcatcgc ttggcatttc gcgaagcgtt
    22201 gggataggca ttttactttg tttcataata ttcctcgatt atctaaaaaa gagtcgcata
    22261 atgtcattcc aagtcacagc aatcatcaag acaaccatga tgaccactcc ggccaaggtg
    22321 acataggttt caatttcttg tttcaatggt ttgcggcgga tggcttctag gatattgagc
    22381 acaatcttac caccatccaa ggctggaatc ggaataagat taaaaatccc aatattgatg
    22441 gaaatcattg ccaagaagta caagatattt tcaattccat ttttagcagc atcactactt
    22501 gccttaaaga tagcaacagg tccacccaac ttgttcaaat ctggttggaa aatcagattt
    22561 ttcagagctg agagaattcg gagagctgag tcagcagcag ttgtaaaacc acctacaaac
    22621 atggatagaa aatctgactt accccccggt tgaacaccta gaaggtaacg accttgacta
    22681 tctttgggtg taacagtgac ttgtttgtca ctcccctttt cagaaatagt cacatccaaa
    22741 gtcggtgccg tcttatcttt ggtttctgtt tccacagctt ggatcaagct ttcccagttg
    22801 ctaacctcat gtgagccaat cttggtaatt tgtgccgttt ctggtactcc taccttggcc
    22861 aaggcacctt ggggcatgat atggaactga ttggtatcaa catctctgac accaccctgc
    22921 ataaagatta aaacccaaaa aacaacgaca cctaagataa aattgttcat aggacctgca
    22981 aaattggtaa tcagtttgcc ccagatagtc gcattttgat attgaacatc taaaggtgca
    23041 atccgaacct cagtaccatc tgcttccaca accgttgcat cgtgatccac tgcaaatgtt
    23101 ttttcttctt ccagaaccaa tcctttgata aagagcttgt cttcaaaatc aaactgggtc
    23161 acctgcatag ggaggactgt ttgatccaat tttttacctg agagattgat gcgtttaacc
    23221 ttaccatcat cagcaagtgt caaactaaca ggcgttcctg tcttgatttc agttgtatca
    23281 tcaccccaac cggccatgcg gacatagcca cccagaggca agattcgaat ggtataggcc
    23341 gttccatcct tgccaatgtg agcaaaaatt ttaggtccca taccgatggc aaattcacgt
    23401 actaaaatcc ctgatttctt ggcaaagtag aagtgcccga actcgtgcac cactacaata
    23461 atcccaaaaa ctagaataaa ggttaaaatt ccaagcatag tgtttcctcc gtcttttgat
    23521 taaaagagtc caaataagtg catgattgga aatacaagca acatactatc gaaacgatcc
    23581 aaaacaccac catgtccagg gataaatttc ccagaatcct taacaccaaa atgacgtttg
    23641 atcgaacttt ctagtaaatc accaaattgt ccagcaatgc taaagaaaat agcaaagact
    23701 gacatcttgt aaattccata tggaagagca actgtactgt caactatcat aaagataatg
    23761 gttactaaaa ttgctcctaa aataccaccc aaggcaccct caagggtttt attaggcgat
    23821 acccttggtg ctaactttcg tttcccatag ttcatcccaa caagataggc accactgtct
    23881 gtcgcccaga cgatacacaa ggctaagaga gccttgtcca aacctgcaac acgagcatct
    23941 agtaaagcat taaatccaaa gcccacgtag aagctcatag caagagggaa aaccgcatcc
    24001 tcaatcgtat aagacttgct aaaaacggtc gttcctaaca tgattgaaat caaaacacta
    24061 taggcaacca cattcccatc aactggcaaa aaagtcaggt aattctccaa gggaatggtc
    24121 aatgcaaagg ttgcaaagag ggtcaagagg ccctccatcg tcatggtctc tagacctctc
    24181 atcttcaaaa gttcatgcat ggctagcatg gctatgattc cgattgctat ctgaagcaag
    24241 aggcccccaa tcattaaaat tggtaggaaa atagccaggg caatccctgc aaacaaggtt
    24301 cttttctgta aatcctgggt catatttcct cctaaactcc tccaaatcgg cgatgacgac
    24361 gattataggc aagaatagct tcctgcaagg ccgcttcgtc aaaatcaggc cataaggtgt
    24421 ccgtaaaata aagctcacta taggctccct gccatggaag gaaattgctc aaacgtaatt
    24481 ctccactagt acggataatc aagtctgggt ctcgtaagtc cttaggcaaa tgctgagtaa
    24541 agagatagtt accaatcaat tcctctgtga tgtcacctgg gttgattttg gcatctaaaa
    24601 catcctggga aatcaactta agcgcctgtg taatctcagc acgtccacca tagttaagag
    24661 caaaattaag aatcaatcct gtgttgttct tagtcaattc ctcagccttg gttaaagctt
    24721 caaaggtttg cttaggcagg cggtctgtct ccccaatcat ttgaatctta acattattcg
    24781 catgtagttc cgggacataa ttatcataaa actctactgg caagttcatg ataaacttga
    24841 cttcctgatc tggacgggtc cagttttccg tagaaaaagc atagaccgta ataaccttga
    24901 cgcccagttt gttggctgcc ttggtcacgg tttgcaatgc ttccatgccc gccttatgtc
    24961 caaaaactcg cggttgcata cgttttttag cccaacggcc attgccatcc atgatgatgc
    25021 cgatatgagc aggaacctgt gtcggaacct ctacttccac agccttatct ttcttaaaaa
    25081 atccaaacat gatcttattc ctattcaaaa atctatcgtt tcattatacc atatttcccc
    25141 attttcttct atcactaagc tatttattct caggcaccat gcccattttt caaaaaaata
    25201 agccgcctga ttgggcgact ttatttttat agggagatta ttatgaaaaa gttttaggag
    25261 tttaagttaa ggtcttctta acttatgaac ttagtgtaca ctccctagct taaagtttcc
    25321 ttaagtattt ttaaaaatca aatttttcca tttctcctgc caatttttct tggataaacg
    25381 tgtttgatag agttccattc ggtcttcatt ttctaagaaa tgaggagttg gacgaacttg
    25441 aaaattcaaa atatcctcca aaccataagg tgcatagagt tcaaaatctg attcttcatt
    25501 caagcgcagt ccaactgccg tacaccgttc tggatactta ctcatagcat cacgagaact
    25561 ggtataggaa gcagtgtgag gactgtgctg gtgcatatag acctgatttt tcaattccca
    25621 ctggtactga ggaaaatcct ctctcagctt tttctccagt aataaggttt cctcataaga
    25681 aaaatctgga tcaaagaaaa tcacatctat atctgtttca tgatcaaaag gggatttgtc
    25741 tgacaaaaga ttccagatga aatttctgac agaacctgct gccaactacg agtctttcaa
    25801 accaaggtct cggatgatcg tcagaatggc catcatatct ggattttctc taaaagcctc
    25861 taagatttct tgcttatttt tcactgtatt cataacctaa gtgctcatat gccttagcag
    25921 tcgccacccg tccagaccgt gtccgcatga taaaaccttt ttgaatcaag taaggctcat
    25981 acatgtcttc aactgtctca cgctcttcgg cgatattgac agaaagagtt cctagaccaa
    26041 caggtcctcc actgtacatc tcaatcatgg tacgaaggat tttttgatcc acatagtcca
    26101 aaccttcatg gtcaacatcc agcatagtca aagccttatc ggtaataata tcatcgatta
    26161 ccccattccc cattatctgg gcaaaatcgc gcacgcgctt gaggagacga ttggcaatac
    26221 gaggggttcc acgactacgt agggccaact cagatgctgc ctcatgagtg atttccatct
    26281 caaaaatatc tgccgtccgc tcgacaattt ctgtcaagtc agcatgggca taatactcca
    26341 tatgacctgt aatcccaaaa cgtgcccgta gtggatttga gagcatacca gcccgagtcg
    26401 tcgcaccaat caaggtaaaa ggaggcaact ccaaatgaac actgcgactg ccttcaccag
    26461 ccccaatcat aatatcgatg tagaagtcct ccatggcact ataaagcact tcttccactg
    26521 acatgggtaa gcgatgaatc tcgtcaataa agaggacatc tccaggctct aactcattca
    26581 aaatcgctac caaatcaccc gctttttcga taacaggacc agacgtttgc ttgagattga
    26641 ctcccagttc attggcaatg acaaaagcca tggttgtttt cccaagccct ggagggccaa
    26701 ataagagcac atgatccagc gcttcatccc gcattttagc ggcttcgata aagatctgaa
    26761 gctgatcctt aaccttatcc tgaccaatat attcacgtaa atactgagga cggagcgtgc
    26821 gttctactaa ctcctcatca cccatcatct cattatctaa aattctactc atggctctat
    26881 tatatcaaaa aaacaagcca caaacaaaaa agccacctga ttgggtgact cctaagttta
    26941 gcacttatgt ggtataatat tatacggcac ttctacaccg cctacgaaag gaggtgagat
    27001 agcccatgat ggaattagta ctcaaaacta tcatcggacc aattgtggtc ggtgtcgttc
    27061 ttcgtatagt cgataaatgg ctaaacaagg acaaatagtg tcaaaaaaga cctcaagctt
    27121 atttggtcgt gagcttgggg tcttttctag cctatgatat agaactagta ctcaattcct
    27181 ttttattatc ccatagttca cgaattttgt caaaggttta cattttcttc aaccgctgta
    27241 cgacaagacg gttaagatta agagaacgtt agggattcta tcaatttcat agaaattttg
    27301 atttcgtaaa cgaagagaca atcttacatg tcacttctca tttaatacgc cactactaga
    27361 caagcaaaat cattattaca gtagttccag ttcttcaatt aacagtcact tacaatcaaa
    27421 ttgagtttga actagctgaa gcgaccacag acctatttct tagt
//
LOCUS       DBERAE010000027        26421 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.27, whole genome shotgun sequence.
ACCESSION   DBERAE010000027 DBERAE010000000
VERSION     DBERAE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.27"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..2351)
                     /locus_tag="ACL70N_001340"
     CDS             complement(<1..2351)
                     /locus_tag="ACL70N_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGS0590129.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEYNDHLEITAYHISDDVMQRSITPVS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSILLDGKHSIVGT
                     WEGELVRDNFAITVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKTVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYLSLTFDDKAGIGG
                     SRASGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAK
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRQAGASSSLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQAEALSRTKNELAGA
                     SSSLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSV"
     gene            complement(2352..3074)
                     /locus_tag="ACL70N_001341"
     CDS             complement(2352..3074)
                     /locus_tag="ACL70N_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGS0590130.1"
                     /translation="MTKINELTIDGVKTSSFKCEILVETRPQIIVSSSKTSLLEHDGI
                     SGAIVQSNRHRRLIEKSYHISLINPTDEDLYRFSSLLNREKFWLENEQEPSVKYWCYK
                     VDDFKIIKDDFGAWTVDVKFTCHPTKYFKGSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSAVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(3071..5809)
                     /locus_tag="ACL70N_001342"
     CDS             complement(3071..5809)
                     /locus_tag="ACL70N_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGS0590131.1"
                     /translation="MTETFEGLYVKFGANTVEFDRSVKGINNALSSLKKDFNNINRQL
                     KMDPDNVDLLNRKLLNLQEQARVGAMKIAELKKQQKELGESEVGSAQWNKLQLEISKV
                     ESQMKVVDQTMNSTKKHIEDVGNPKSILNLNKEINNVAKELDIVNQKLELDPKNVELS
                     EEKMKLLGKQSSLAKDKVQELKRKQEELGKEKIGTEEWRQLQNEIGQAEVEVLKIDKA
                     MGNLGDSSRSATGNIKEATGYLKADVMMNIAEKAGQLGQKMVDAGKKTVDAWSEIDEA
                     MDTVTTKTGLTGEALLGLQEIAKGIATSLPSATFQESADAVGELNTQFGLTGDTLQSA
                     AEYLLKYSKITGEDISNSAINAKKAIDAYGLSNEDLARVLDSVTKVGQDTGQSYDSIF
                     QKAIDGAPQIKMLGLSFKEGATLIGRFEKSGIDSSAALASLSKATVNYAKDGKTLTEG
                     LNETVNAIQNATSKTEAIRIASEVFGNRAAPKMVDAIQRGAFSFNDLAEAAQNSSGTV
                     ATTFAETKDPFDDLTTYSNKAKEGLAEIGGTLLETVIPALEPLMGMLESAVNWFTSLN
                     ETDQQTIVILGLVTTAVMLLLGAIAPLVIAIGAIGAPVGIVVAAIVAAIAAITLIIQA
                     IMNWGTISEWLQSTWDACAAWLSELWTNIVTTATTAWSSFTAWLSEIWSSVVSTGQSL
                     WSSFTSTLSNIFSSLISGAQSLWSSFTSTLSNLWSGLVSTGSNLFNNLSSTISGIFNG
                     ILSTASNIWNSIKSTISNAIDGAKNAVSNAIQAIKNLFNFNISWPHIPLPHFYVSGSA
                     NPLDWLSQGVPSIGIEWYAKGGIMTKPTLFGMNGNRAMVGGEAGAEAILPLNKSTLGA
                     IGQSIANTMNTSNSINVNFSGVTIREEADLNRLADVVGTRIAEELQRKTNLRGGFA"
     gene            complement(5996..6472)
                     /locus_tag="ACL70N_001343"
     CDS             complement(5996..6472)
                     /locus_tag="ACL70N_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590132.1"
                     /translation="MIKKELSFTAFDSYGEERERTETVRFLYSLPAIKMYEQRTGRNF
                     FDDNQKALTAYTQLALATGVNGRLSALTDEEKVKLMPLLMEPDFMNFLTEVIPCLYGE
                     VENGRLVQNELTAETASLAPWFGDLIDIGFFSDLFYEFNRSRAKVPQDRKKPQQKS"
     gene            complement(6474..7142)
                     /locus_tag="ACL70N_001344"
     CDS             complement(6474..7142)
                     /locus_tag="ACL70N_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGS0590133.1"
                     /translation="MTYKYDTREVTHGNTTGFFAKISKTESGTLDLKKPYPFTGLRKT
                     SFETSQESNAYYADNVEHVRLQGKKSTEGSITTYQIPKQFMIDHLGKKLTTSTPPALI
                     DTGVNANFIWGYAETVTDEFGSEVEEFHIWTNVKASAPKGSTTTDESSATPKEIEIPC
                     TASPNNFILDSDKKPVSEIVWRDTDKGVVRAKFDKLFASSTPMKLIDFINEALGTTAI
                     VPGG"
     gene            complement(7156..7500)
                     /locus_tag="ACL70N_001345"
     CDS             complement(7156..7500)
                     /locus_tag="ACL70N_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000534622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HGS0590134.1"
                     /translation="MGSGSVNVKTLKIDIQNQVLEIIEKAGKSTAGDIRDGSPRRNGV
                     YEKGWTHETIEDIAVVYNNGKEKSLAHLLENGHATKNGGFVAPQEHIRPAYLKNKEIF
                     LNNMKSIKIRPN"
     gene            complement(7487..7834)
                     /locus_tag="ACL70N_001346"
     CDS             complement(7487..7834)
                     /locus_tag="ACL70N_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590135.1"
                     /translation="MAKKFFTRQEIQEILEKNTLKSKVFYMEREEKSSPDNVILYYRL
                     TPGSSITADDTVHMRKVTIQISHYHKKKLDSIEELMLSNFMCEPSQLNLKQPDTDYLL
                     TTYRIEVFTSGKW"
     gene            complement(7834..8139)
                     /locus_tag="ACL70N_001347"
     CDS             complement(7834..8139)
                     /locus_tag="ACL70N_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HGS0590136.1"
                     /translation="MKSSRVSIILCYDERTEVEKGVFEKQVVEKKVKAEKEKIYQRRL
                     DKALADGQVLTARFRIRSNYVTDSLDYVKYKGKEYKVNVGTESDDDHYTIIELGELK"
     gene            complement(8136..8471)
                     /locus_tag="ACL70N_001348"
     CDS             complement(8136..8471)
                     /locus_tag="ACL70N_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590137.1"
                     /translation="MTILNQIKEMVEVDVEEEIFDTQFLSYINSGISYLTRNNIPINR
                     IDKESELTEWNEIEEDDKETILDWLHLRCVQRFDKSLMTGNSTTRSWIDEELTNILYQ
                     LKAIYGVKS"
     gene            complement(8497..9750)
                     /locus_tag="ACL70N_001349"
     CDS             complement(8497..9750)
                     /locus_tag="ACL70N_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGS0590138.1"
                     /translation="MKTLVELMEERQKHADELSEIKFKKASIEEKLESATIGEEELAQ
                     LKSDAEGLVSKADELKNTISKLDVEIEEKQDNLNKAAKSIKEVQKGKIQMEYLKTKEA
                     ALDFARILMDNEGSSNSARKAWEANLVEKGVTDVNKILPEPVLIAIQNAFNDYDGILN
                     HVTKDPRYAVRVALQTQQAKAKGHQNGKTKKDESFVFIDYTINSAAVYIKYSFEYADL
                     KKDTTGAYFNYVMNELAQGFIRAVERAVVIGDGKNSDDDDKITEIKSIAEETLAQLFD
                     TQEISVDGEFDSTVLENLVKGIDKLAANTTPILVTSKTIARKLKMVKDGEKRYIDPQP
                     FAPISQTGNVIAGYQVYVYDWMEDATNPIIAFADKAYKMIGDDVSADRFEDYDVTMNR
                     RHIELASVLGGRLGQYKSAVKFTKG"
     gene            complement(9764..10306)
                     /locus_tag="ACL70N_001350"
     CDS             complement(9764..10306)
                     /locus_tag="ACL70N_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HGS0590139.1"
                     /translation="MEKLKTFVVKSVEEESADFHFEAYASTYGNTDRDGDVMAKGCFD
                     NTLKTKAVVPMCLNHDRNRVIGKHELSVDEKGLRTRSTFNLSDPEAKKTYDLMKMGAL
                     DSLSIGFFINDYEPVDAKQPYGGWIFKEVEIFEISVVTVPANPQATIDNIKGFDMSVV
                     DKRIAQANMKQDIMSKLATI"
     gene            complement(10353..11495)
                     /locus_tag="ACL70N_001351"
     CDS             complement(10353..11495)
                     /locus_tag="ACL70N_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGS0590140.1"
                     /translation="MNKYINNLREVFARIFRPSNRKSTRTYLQRNLNYWRRNSIYLDN
                     IYNKISTDTAQVRFKHVRITRNPTGVDKMEWFENSDLANVLSFSPNPLEIPVVFWANV
                     TRAMLKDGVAVVVPRWENGRLIEIWFAKKTISWTAERVEIMIDDVEIELPLSDVWVFE
                     NPKLNVTSQLNQITELIDINLDALTEKLGRGNSKLRGFLKLPTKAADEHLKKQAKSRV
                     DSMMELAEIGGIAYLEQGEEFMELNKDYSTASKEEMEFLKSQLYHAHGINEKLFTCDY
                     TEEQYRAYYSSVMKLYQRVFSEEINRKYFTKTARTQGNKLLVFFDMADMISFKDLVEG
                     GFKSKYAGLMNSNEFRETYLGLPGYEGGEVFETNLNAVRIEPSESN"
     gene            complement(11504..13216)
                     /locus_tag="ACL70N_001352"
     CDS             complement(11504..13216)
                     /locus_tag="ACL70N_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGS0590141.1"
                     /translation="MVEMRYFDKYAQLVYSGKIRVCELTMKSIKRVERYKEQYIFKQE
                     EVDKRIEFIEEECSNTKGLAGKLHLALPQKVWLETTWGFYHTVEVTKTDPDTLEEYKD
                     FEERRLIHEVPIIVPRGTGKTTLGSAIGEVGQIIDGEWGADIQLLAYSREQAGYLFNA
                     SRAMLSNEESLLHYMREADILRSTKQGILYETTNSLMSIKTSDYESLDGTNAHYNIFD
                     EVHTYDDDFIKVVNDGSSRKRKNWITWYISTNGTKRDKLFDKYYNIWVDILDEKIVNH
                     SVMPWIYQLDDVSEIHNPDMWQKAMPLLGITTEKETIAKDIEMSKNDPAQQAELMAKT
                     FNLPVNNYLAYFSNEECKGWLDKFDKSLFVGNEERSARCVLGVDLSDVNDICSVSFMV
                     VRGEERQYLNKKFMPRHTIEGLPKELRDKYAEWELSGQLHVHELDYNDQAYIFEELRQ
                     FMSENRILPVAVGYDRWNAKELIRLINDYYGDICHDIPQTVKSLSNPLKVYKEKAKMG
                     KIIFDDPVATWNHANVRVKIDANNNVFPNKEKAKEKIDVFASQLDAFICYENFKEDLS
                     YYFD"
     gene            complement(13209..13694)
                     /locus_tag="ACL70N_001353"
     CDS             complement(13209..13694)
                     /locus_tag="ACL70N_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590142.1"
                     /translation="MILKINEVLEKLGISRATLTRYRKKLGIFEETRSNITKSQFKEL
                     EKLANQRQKYTREERVELSRKTFKLIPKEKMLEINDNDSVGLKNLKTQYNHNQKVIEN
                     FQLEINKVINDGELPDKYLLDGMEKYQKLNMQIMSTIEKQSPQGDSLKEMIQEKLARY
                     G"
     gene            complement(13831..14148)
                     /locus_tag="ACL70N_001354"
     CDS             complement(13831..14148)
                     /locus_tag="ACL70N_001354"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGS0590143.1"
                     /translation="MTFKNPKHSDWFRTWQIKFYNSKPWRTLRNRIRSIKRMRCDMCG
                     RLIHGKSIVDHIIEIDETNYQDESITLNEDNLQLLCLECHNTKTFQSKINLNLENRNI
                     NLF"
     gene            complement(14578..15120)
                     /locus_tag="ACL70N_001355"
     CDS             complement(14578..15120)
                     /locus_tag="ACL70N_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HGS0590144.1"
                     /translation="MNIVEPLRDKDDIQAMKDYLSSWNEKYYMLFLLGINTGFRVGDI
                     LKLKVKDVQGWHIKVREQKTGKYKSIKMTRPLKNELREFVKDKELHEYLFQSRVGKNK
                     ALSYKTVYWFLKRAAEDLGIDNVGTHTMRKTFGYHYYKKYKNVADLMSLFNHSSPAVT
                     LIYICVRQDELDTKMSNFSL"
     gene            complement(15230..15694)
                     /locus_tag="ACL70N_001356"
     CDS             complement(15230..15694)
                     /locus_tag="ACL70N_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590145.1"
                     /translation="MGKKNLITARRDYLEFELNDKYLQIDKLIGQRRHELERLYEVKH
                     LTVPGIDDTGASGSGTFVNRSENLAVAYASDPMVLRLENFQTAISKLLDVLEPDDKKI
                     FHLKWGEHTRYDWIQVWHKMENGDTGYLYRHSKQIYRRREIILDTLAKLLFM"
     gene            complement(15731..16261)
                     /locus_tag="ACL70N_001357"
                     /pseudo
     CDS             complement(15731..16261)
                     /locus_tag="ACL70N_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            complement(16324..16497)
                     /locus_tag="ACL70N_001358"
     CDS             complement(16324..16497)
                     /locus_tag="ACL70N_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590146.1"
                     /translation="MEDEQNILEIQLILGKQVLEIVLDLLKDDSKTGVVLPLNINDRE
                     FTITVEKEVTDRD"
     gene            complement(16497..16784)
                     /locus_tag="ACL70N_001359"
     CDS             complement(16497..16784)
                     /locus_tag="ACL70N_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590147.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEEVE"
     gene            complement(16784..17308)
                     /locus_tag="ACL70N_001360"
     CDS             complement(16784..17308)
                     /locus_tag="ACL70N_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGS0590148.1"
                     /translation="MNKQELIEKYKELENSSFDIAAIVVCQLVLKDLEQLDEPKPVKV
                     KQFVADWYEENKDSFEFNVWDWIAFRDEAKKSENREFNNWINNTRENPIQTLVNMHNF
                     GYEVEKEKRYLVKVKGVHFTNYLISGNRKDIWFFHSAYEPEHQIIAHTRKELEEAGFG
                     WVFDCPGIEIEEVE"
     gene            complement(17310..17624)
                     /locus_tag="ACL70N_001361"
     CDS             complement(17310..17624)
                     /locus_tag="ACL70N_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590149.1"
                     /translation="MEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPGMSQVVIAVYLIYR
                     GN"
     gene            complement(17599..17808)
                     /locus_tag="ACL70N_001362"
     CDS             complement(17599..17808)
                     /locus_tag="ACL70N_001362"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590150.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKVEELEGDGRVKAKS"
     gene            complement(17795..17962)
                     /locus_tag="ACL70N_001363"
     CDS             complement(17795..17962)
                     /locus_tag="ACL70N_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590151.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            complement(18089..18316)
                     /locus_tag="ACL70N_001364"
     CDS             complement(18089..18316)
                     /locus_tag="ACL70N_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590152.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            complement(18316..18510)
                     /locus_tag="ACL70N_001365"
     CDS             complement(18316..18510)
                     /locus_tag="ACL70N_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590153.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            complement(18525..19295)
                     /locus_tag="ACL70N_001366"
     CDS             complement(18525..19295)
                     /locus_tag="ACL70N_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0590154.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     TDIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(19289..19447)
                     /locus_tag="ACL70N_001367"
     CDS             complement(19289..19447)
                     /locus_tag="ACL70N_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590155.1"
                     /translation="MGILELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(19435..20262)
                     /locus_tag="ACL70N_001368"
     CDS             complement(19435..20262)
                     /locus_tag="ACL70N_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS0590156.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            complement(20255..20548)
                     /locus_tag="ACL70N_001369"
     CDS             complement(20255..20548)
                     /locus_tag="ACL70N_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590157.1"
                     /translation="MEELIEWLETKEKLNREMISDEETSDFNLHLENDNDTMFMIKEY
                     LNDYNKLAKDYRILSSENRLLKLEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(20564..20884)
                     /locus_tag="ACL70N_001370"
     CDS             complement(20564..20884)
                     /locus_tag="ACL70N_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590158.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIRGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRFL"
     gene            complement(20970..21227)
                     /locus_tag="ACL70N_001371"
     CDS             complement(20970..21227)
                     /locus_tag="ACL70N_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS0590159.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(21240..21950)
                     /locus_tag="ACL70N_001372"
     CDS             complement(21240..21950)
                     /locus_tag="ACL70N_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HGS0590160.1"
                     /translation="MNEIFNFHGQEVRTVMFDDEPWFVGKDIAEILGYVNSRDALAKH
                     VDEDDKLTSQIATAGQMRNQTVINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQASMIEDIDYLKSEQPIHPSYAKSLLKKRKAR
                     VVACLGGIDSPAYADKIFAQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTWE
                     PSTNTKMKIMKLNSFDEG"
     gene            22005..22682
                     /locus_tag="ACL70N_001373"
     CDS             22005..22682
                     /locus_tag="ACL70N_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002878731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HGS0590161.1"
                     /translation="MYVPIKPTGDFSTNFTLSDSCKICKNITCPTVVNETTQSIDNDH
                     YRFCATRYCQQCNHYFVDEIEVTITVDSFANIDYQYDILDVKPELPSDIPISKELAKL
                     SPIGKEIYTQALKAEQEKLDHIAGIGFRKSLEFFVKDFVISFELENKDKVAKMPLKQV
                     IDNYIDNQNLKTFATATVYIGNDETHYTKKHSDKDLQDLKKFLHGFLHYMEMQLNLLD
                     AYQLLDR"
     gene            complement(22645..22773)
                     /locus_tag="ACL70N_001374"
     CDS             complement(22645..22773)
                     /locus_tag="ACL70N_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590162.1"
                     /translation="MNELERTALNEILRTVTYIAEKLDKIETAMLTYQEADKHPKD"
     gene            complement(22783..22980)
                     /locus_tag="ACL70N_001375"
     CDS             complement(22783..22980)
                     /locus_tag="ACL70N_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590163.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(23007..23231)
                     /locus_tag="ACL70N_001376"
     CDS             complement(23007..23231)
                     /locus_tag="ACL70N_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HGS0590164.1"
                     /translation="MKFDYSKLNGRITEIFNSKKKFAKAMKLSERSISLKLNNQRYWK
                     NNEITTACNLLLIPDNQIGDYFFKPEVQET"
     gene            23405..24187
                     /locus_tag="ACL70N_001377"
     CDS             23405..24187
                     /locus_tag="ACL70N_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003139890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGS0590165.1"
                     /translation="MKTTTSLRLKQILSERNLRQVDILNSSLPLQKELGIKMGKSALS
                     QYVSGKSSPDQDKLVLLSKTLGVSEAWLMGYNVPMSDDTPVQELKIPTSPLVQKITEK
                     AVQLSTPRKQKVLNYANEQLKEQNNKVIMIEENLFEYRVFEKLSAGTGFSYFNDGNYD
                     TVFYDKDLDHDFASWVFGDSMEPKYMNGEVVLIKETGFDYDGAIYAVDWDGQTYIKKV
                     YKEKDGLRLVSINNKYKDKFAPFEEDPRIIGKIVGNFMPIEN"
     gene            24200..25114
                     /locus_tag="ACL70N_001378"
     CDS             24200..25114
                     /locus_tag="ACL70N_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HGS0590166.1"
                     /translation="MKIGMRKPSPIRSLKARTTSKWKRQAKKALIPGYGKKGMGWVKN
                     PKKAMYNKVYHKTTFGLSDLFKSSKKRKKKVVNNKQQSILASNGKKQHTSKEYKEAGL
                     VFMVLGAIFLFLFLPLGFFLFITGFITYIIGLLTANREKKKKVENYSPQIDTIVFRDD
                     FLLMGTNYHQEEAEIAADFLSKGVHYFGKDNKSLKSYMLETYKPVYKYNKLKTVDVHL
                     LPEPSNPHDKNAVKVLVNNIFVGYLPAMIATQVSSYISNPNYRYDAILTGRGGPYKTL
                     NIETERVVSRKSDLTYYLDLTVWRLAKK"
     gene            25285..>26421
                     /locus_tag="ACL70N_001379"
     CDS             25285..>26421
                     /locus_tag="ACL70N_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0590167.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSTLLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLS"
BASE COUNT         7486 a         5719 c         4418 g         8798 t
ORIGIN      
        1 actgagacac ggtcttcttg gtcttcatac gctggttgat aggctggaaa ataattacca
       61 accgataaca tagcgttctc aatgacgacc tgcagaccag caggaaatcc ataattagta
      121 ccaaaacgaa tgaacacatt attagtctga tagtcctcag aagaactaga caagtcaatc
      181 gtaaactcaa aatgttggcg ttcgacagtt ccacctttaa aaattaagtt tctgtaggca
      241 taccatggat gagcactaaa atgcaccata gcaggcatgt catttactag ggcgacaggg
      301 aaagtcacat caaaagatat gcgaacataa tcacgcttga acctgtcact gttcttccag
      361 aaatcaggaa ctatgaatgt tcgatagtcg tataccgctt gacctcctgt tgtgaacgtt
      421 cttgaacgtg aattcctgaa gtaattccgt gaactacctg cctgcacact cgcaatccga
      481 ctagctagct cctcagctgt ctgcgtaagt tctgacttgc tggctttacc attggccaag
      541 ttggtcagtt ctgacagtct acgagtcgtc gtctccttat acgtcgcttg cgctgacttc
      601 acgccagcca gttcattctt agtccggcta agtgcttcaa cttgcttggc aatctcagct
      661 tcagcctgtg cttgcttcgg tcgaatatcg tttgcgatag ttcgttttag aacatccaag
      721 tcacctgaca aagccgtctg agcgctcgta gtctgcgact taaacgcttc aagtctagca
      781 acagaatcca gctcaatccg cttggcttcc tgagcaagag agctacttgc gccagccagt
      841 tcatttttag tccggctaag tgcttcagct tgcttggcaa tctcagcttc aacctgtgct
      901 tgcttcggtc gaatatcatt cacgatagtc cgtttcagag cgtccaagtc acctgacaga
      961 gccgtttgtg cgctcgtagt ctgcgactta aacgcttcaa gtctagcaac agaatccagc
     1021 ccaatccgct tggcttcctg agcaagagag ctacttgcgc cagcttgtct caaagcttcc
     1081 tcagccttgc gcttagtttc tttcaatggc ccgttgtcaa agctattaaa gcgctgattg
     1141 atagtgtcag acagttctcg cttgacttct tccgccttgg ccttggcaag ttcaatatcg
     1201 tcagaaattt cctgtctaag caatccagcc ttatgatcaa agtctaagtc agcattttga
     1261 agagcctttt caagggcgat ttcttgtgca gattctgtca ctccaagaat tgcatcggct
     1321 gcgctagata ggccaccaga agctctagaa ccaccaatac ctgccttatc atcgaaagtc
     1381 agagagaggt attcttcttt taaggcatcg aactcataag caatagcttt cttgaatgca
     1441 tcgacattat gtttccagct cttgagattg accgtgtcgc ccatatggac cacttgccca
     1501 tcaagttcat aagcttcaat cttgatagca tcagagacct tgtcaattcc ctcatttgag
     1561 aacttagact gtgcccactt ctgcaactct tcaacagttt tagcattgtt gttctcatac
     1621 tctttttcat tgatataagg gtatgagttg ataagaggac tatcaacagt cactctgata
     1681 gtcgtttctt tttcagcacc ttcaggttta aaagtcgact ttgcgtgaat tcttgtgaca
     1741 acattctgac tgttttttgt gcgttggtag ttcttcagat ttttgtgcgt tgtaataaca
     1801 acaccacgat tctccccacg actcttcttg acagttatcg caaagttatc acgaaccagc
     1861 tcgccttccc atgtaccaac aatgctgtgc ttaccgtcca gcaatataga gtatagggtt
     1921 tctgtttcag tcgtattgaa ggtcctacgg tcctggatat cactgttgaa tgagaagtct
     1981 ccaagagccg ttttggtgtt ttgtaccatg cgagaaagag ccatgccaca actctgacta
     2041 gtcacactta ctggtgtgat agaacgttgc atcacatcgt ctgaaatgtg ataggctgtg
     2101 atttccagat gatcattgta ttcaacaggt ttcttaatgc gaaatagctg cgcaccaaga
     2161 acaggagtcg gcgcttttat caacatatct tcttggatga gctgataaat accagagtcg
     2221 gaaatgggat atttcacagt taaggtgaaa tcaccattca tgatctcttt aacaatcgcc
     2281 gaagtcgctt catgaagtgg ctccccgttc catcgaacag ttcttacatc tttattaagt
     2341 agataaagca attatgccca cccccaaacc gtttcgattt caatcgattg aatacctggg
     2401 cctaaaacaa ccccaatatt cttaactttc gctggatcaa ctgtaataaa atcccctgac
     2461 catttgactg gcttccctgt tgtcgtttta aagctaggat tgtcaggatt attaaccatc
     2521 acaagcgatt ctgagagttt ttcaagccta atgacctgac cagcgattgt aaatgaagtc
     2581 tcaacagcgc tctgaccaac gattgtgatt ttaggaaaag caagagcaga accttgaacg
     2641 gtcaaggttc cacttcttgt caatctctgt gtatcggagc ctttaaagta ttttgtagga
     2701 tggcaagtga attttacatc caccgtccat gcaccaaaat catctttaat aattttgaaa
     2761 tcatccactt tatagcacca atatttcacg cttggctctt gttcattctc taaccaaaat
     2821 ttttcacgat ttaacagaga agaaaaacgg tataagtctt catccgttgg gttaatcaag
     2881 ctaatgtggt agcttttttc aatcaaccta cgatgcctat ttgattgaac aattgcacca
     2941 ctaatcccat catgttctaa aagactagtt tttgaggagg atacgatgat ttgtggtcgt
     3001 gtttcaacca gaatctcaca tttaaatgat gatgttttca ctccatcaat ggttaactca
     3061 ttaatttttg tcatgcgaaa cctcctctca aattagtttt tctttgtagt tcttcagcaa
     3121 tacgtgttcc gactacgtca gctagtctat tcaaatccgc ttcttctcgg atggtcactc
     3181 ctgagaagtt gacattgatg ctattcgatg tattcatcgt attagcaatg ctttgtccaa
     3241 ttgcaccaag agttgactta ttgagtggaa ggattgcttc tgcaccagct tctccaccaa
     3301 ccattgctct atttccattc attccaaata aagttggttt ggtcatgata ccacccttcg
     3361 cataccactc aataccgatg cttggaacgc cctgacttaa ccagtctaat ggattggctg
     3421 aaccacttac atagaagtgt ggtaatggaa tgtgcggcca actgatattg aaattaaata
     3481 gattcttaat agcttggata gcgttagata ctgcattttt agcaccatca atagcatttg
     3541 aaatagttga tttgatagag ttccaaatat tgctagcagt ggataagata ccattaaaaa
     3601 ttcctgaaat cgtgctactc aaattattaa acaaatttga cccggttgag accaggccag
     3661 accataaatt ggaaagggta gaagtaaaac ttgaccacag tgactgagct cctgaaatca
     3721 aacttgagaa aatattggac aaggtgctag taaagctaga ccacaaagac tgtcccgttg
     3781 agactactga agaccaaatt tcagaaagcc aagcagtgaa acttgaccac gctgtagtag
     3841 cagtcgtaac aatattagtc cacaattcag aaagccaagc ggcgcaagca tcccacgtcg
     3901 actgaagcca ttcagatatg gtcccccagt tcatgatggc ctgaatgatg agtgtaatag
     3961 cggcaatagc agcaactatt gccgctacga caattccgac aggcgcacct attgcaccta
     4021 tagcaatgac tagcggtgct attgcaccaa gcagtagcat tacagcagtt gtaacgaggc
     4081 caagaatcac gatagtctgt tgatcagttt catttaagct ggtaaaccaa ttgacagcag
     4141 attcaagcat gcccatcaaa ggttctaaag ctggtataac agtctcaagt agtgtaccac
     4201 ctatctcggc aagcccttct tttgctttgt tggaataggt tgttaggtca tcaaatggat
     4261 cttttgtctc agcaaatgtt gttgctacag ttcctgatga gttttgtgct gcttcagcta
     4321 aatcattaaa actaaatgcc ccacgttgga tagcatctac cattttagga gcggctctat
     4381 ttccgaaaac ttcagaagca attcttattg cttctgtctt actagtagca ttctgaattg
     4441 cattgacagt ctcgttcaac ccctcagtca atgtctttcc gtctttagca tagtttactg
     4501 tagcctttga aagtgaagct aaagctgcag aagagtcaat cccacttttt tcaaatctac
     4561 caattaatgt cgccccctct ttaaaagata atcctagcat cttaatctgt ggagctccat
     4621 caattgcttt ttgaaagatg gagtcataag attgaccagt atcctggccg acctttgtta
     4681 ctgagtccaa tactctcgct agatcctcat tagataaacc gtaagcatca attgctttct
     4741 tggcatttat tgcggaattt gaaatatctt ctccagttat tttcgaatat ttcaataggt
     4801 actctgctgc agattgcaaa gtatcaccag taagtccaaa ttgtgtattt aactcaccaa
     4861 ctgcgtcagc agattcttga aatgtagccg atggtaagga tgtagcgatt ccttttgcaa
     4921 tttcctgaag tcctaacaag gcttcgccag taagtccagt cttcgtcgta acagtatcca
     4981 tcgcttcgtc gatttcagac catgcatcta ctgttttttt accagcatca accatttttt
     5041 gacctagttg tcctgccttt tcagcaatgt tcatcattac atcggctttt aagtatcctg
     5101 tagcttcctt gatgtttcct gttgctgaac ggctcgaatc ccctagattc cccatggctt
     5161 tatctatctt taacacctcg acttctgctt gcccaatttc attttgaagt tgtcgccatt
     5221 cctctgttcc gattttttcc tttcctaatt cctcttgttt ccgtttcaac tcctggacct
     5281 tatccttggc taatgaagat tgtttaccta ataacttcat tttttcttcg gacaactcta
     5341 catttttagg atctaattca agcttctggt tgacgatatc aagttctttt gcaacattgt
     5401 tgatttcttt gttgagattt aaaatagact ttggatttcc tacatcttcg atatgttttt
     5461 tggttgaatt cattgtctgg tcaacaacct tcatctgtga ttcaacttta gaaatttcaa
     5521 gttgaagctt attccactgt gctgacccaa cttcagattc tcccagttcc ttttgttgct
     5581 ttttgagttc agcaattttc atagcaccaa cacgagcttg ttcttgtaag ttgagcaact
     5641 tacgattcag caagtcgaca ttgtctggat ccatcttcaa ttgtctattg atgttgttga
     5701 aatctttttt cagactagat aaagcattat tgataccttt tacagatctg tcaaattcaa
     5761 cagtattagc accaaatttg acatataagc cttcaaatgt ttcagtcata gatttcctcc
     5821 tttcagtttt agtcagacat tacatttagt aattctgcgt ttgataaagt tttcttctca
     5881 ttttcattga tactcatctg atgtagtgtt cccatcagat aattaaagtg ttgactttct
     5941 gcccaaaaaa catccatccg attttcaaaa acaaccttat aaattttttc agaagttatg
     6001 acttctgttg aggctttttt ctatcttgag gaacctttgc tctacttcgg ttaaattcat
     6061 aaaagaggtc tgaaaaaaaa ccaatatcaa tcaaatcacc aaaccaagga gcaagagagg
     6121 ctgtttcagc agtcagctca ttctgtacca agcgaccatt ctcaacctca ccgtacagac
     6181 aagggatgac ttcagttagg aagttcatga aatctggctc cataagtaat ggcattagtt
     6241 tgaccttttc ttcatcagtt aaagcagata aacgaccatt tacaccagtt gcaagagcaa
     6301 gctgtgtgta agctgtgagt gctttttggt tgtcatcaaa gaagttgcga cctgtccgct
     6361 gttcatacat cttgatagct ggtaaagagt aaagaaagcg cactgtttca gtgcgctctc
     6421 tttcttcacc ataactatca aacgctgtga atgatagttc ttttttaatc attttatcct
     6481 cctggcacga tggctgttgt tcctaaagct tcattgataa aatcaatcaa tttcattggg
     6541 gtacttgaag cgaacaattt atcaaattta gcacggacaa cacccttgtc tgtatcacgc
     6601 catacaattt ctgaaacagg ttttttatct gaatctagaa taaaattgtt gggtgacgca
     6661 gtacatggaa tttcaatttc ttttggtgta gcagaacttt catctgttgt agtgctgcct
     6721 tttggagctg atgcttttac attggtccag atgtggaact cttcaacctc agaaccaaac
     6781 tcgtctgtaa ccgtttcagc atatccccaa ataaaattcg cattcacacc agtatcgatg
     6841 agcgctggag gagttgaagt tgtcagcttt ttacccaagt gatcaatcat gaattgttta
     6901 ggaatttgat aagtcgtgat ggatccctca gttgatttct taccttgaag acggacgtgc
     6961 tccacgttat ctgcgtagta tgcatttgat tcttgtgaag tttcaaaaga tgtttttcgc
     7021 aatcctgtaa atggatacgg tttttttaaa tcgagtgtgc cagattctgt tttggaaatc
     7081 ttggcaaaga atcccgtggt attaccatga gttacctctc gtgtgtcata tttataagtc
     7141 attgtgactc cttccttaat ttggtctgat ttttattgat ttcatattat tgagaaagat
     7201 ttctttattt ttgaggtatg ctggtctgat gtgttcttga ggtgctacaa atccaccatt
     7261 ttttgttgca tggccatttt ctaacaagtg agcaagcgac ttctctttcc cattgttata
     7321 tactacagcg atatcttcaa tggtctcgtg agtccatcct ttttcatata ctccgtttct
     7381 tctaggactt ccgtctctaa tgtctccagc ggtgcttttt cctgcttttt ctatgatttc
     7441 taaaacttga ttctggatat cgatttttaa tgttttcaca ttaacgctac cacttcccac
     7501 ttgtgaatac ctcgattctg taggttgtaa gtaagtaatc tgtatcaggc tgttttagat
     7561 tcaactgact aggttcacac ataaaattag acaacatcaa ttcctcaatg ctgtctaatt
     7621 tcttcttgtg atagtgactg atttgaatag tcacttttct catgtgtact gtgtcatcag
     7681 cagtaatact actacccgga gttaaacgat agtaaagaat aacgttgtca ggagaggact
     7741 tttcctcacg ttccatatag aacacttttg attttaaagt gtttttttct aggatttctt
     7801 gaatttcttg cctggtgaag aacttcttag ccattatttc aattctccta attcaattat
     7861 cgtgtagtgg tcatcatcag attcagttcc aacatttacc ttgtactctt tccctttgta
     7921 cttcacgtag tctaaggaat ctgtcacata gttagaacgt atccgaaatc ttgctgtcaa
     7981 aacttgacca tctgccaaag ctttatcaag tctacgttgg tagatcttct ctttttcagc
     8041 tttgactttc ttttctacaa cttgtttttc aaaaacacct ttttcgacct ctgtacgctc
     8101 atcgtaacaa aggatgattg atactctaga tgatttcatg atttaactcc gtaaatagct
     8161 tttaattgat aaagaatatt tgtcaattct tcatcaatcc agctccttgt tgttgaattt
     8221 cctgtcatca aggatttatc aaatctctga acacatctca aatgtaacca atctaaaatt
     8281 gtttctttat catcctcttc aatctcattc cattctgtca attcgctttc tttatcgatg
     8341 cgattgatag gaatgttgtt tctcgttaga tatgaaatcc cactatttat gtagcttaaa
     8401 aattgagtgt caaagatttc ttcttcgaca tcaacttcaa ccatttcttt aatttggtta
     8461 aggattgtca ttttagactc ccctttctat ttaaaatcaa ccttttgtga atttcacagc
     8521 tgatttgtac tgaccaagtc ggccaccaag cacgctagca agttcgatat gacggcgatt
     8581 catcgttaca tcataatctt caaagcgatc agcagaaaca tcatcaccaa tcatcttata
     8641 agccttgtca gcaaatgcga taattgggtt agtcgcatct tccatccagt catagacata
     8701 tacttggtaa ccagcaatga cattccctgt ttgtgaaatt ggtgcgaatg gttgtgggtc
     8761 aatgtagcgt ttttcgccat ccttaaccat tttaagttta cgagcaatgg tttttgaagt
     8821 taccaaaatt ggagttgtat ttgcagcaag tttatcaatc cctttgacga ggttttctaa
     8881 aacagtactg tcaaattccc cgtcaacact gatttcttgt gtatcaaata gttgagcaag
     8941 tgtttcttct gcgatagatt taatttcagt gattttgtca tcatcatcac tatttttacc
     9001 atctccgata acaacagcac gttcaactgc acggatgaag ccttgtgcta gttcattcat
     9061 cacatagttg aagtaagcac ctgttgtatc cttcttcaag tcagcatact caaaactgta
     9121 cttgatgtag acagctgcag agttgattgt ataatcgata aatacaaaag attcatcttt
     9181 ctttgttttg ccattttgat ggcctttagc ttttgcttgt tgcgtttgaa gcgcaacacg
     9241 tactgcataa cgaggatctt tggttacatg gttcaggata ccatcgtaat cattaaatgc
     9301 attttggatt gcaatcaata ctggttcagg taagattttg ttaacatcag ttacaccttt
     9361 ttcaaccaga tttgcttccc acgctttgcg ggcactgttt gagcttcctt cattatccat
     9421 aaggattcga gcgaaatcaa gtgcagcttc ttttgttttt aagtattcca tttgtatctt
     9481 gcctttctgt acttccttga tagatttagc agctttattg agattgtctt gtttttcttc
     9541 aatctcaaca tctaacttag aaattgtgtt cttgagttca tctgctttgg ataccaatcc
     9601 ttctgcatcc gatttcaact gtgcaagttc ttcttctcca atagttgctg actccaattt
     9661 ctcttcgatt gaagcttttt taaatttgat ctcagataac tcatctgcat gtttttgtcg
     9721 ttcttccatc aattcgacta gtgttttcat tttttctcct tttttaaatc gttgcaagtt
     9781 tactcatgat atcttgcttc atgttcgcct gagcgattcg cttgtcaacc acagacatat
     9841 caaatccctt aatattatca atggttgctt gaggattggc tggcacggtc acgacagata
     9901 tttcaaagat ttcaacttct ttaaaaatcc atccaccgta aggttgctta gcgtcaactg
     9961 gctcataatc attaataaaa aatccaatgc tcagactatc cagtgccccc atcttcatga
    10021 ggtcataggt tttcttagct tctggatcgc ttagattgaa tgttgaccgt gttcgcagac
    10081 ctttttcatc taccgacagc tcatgcttac cgatgacgcg attgcggtcg tgatttaagc
    10141 acatagggac gacggcctta gttttcaggg tattgtcaaa acaccccttg gccatcacat
    10201 caccatctct gtcggtattg ccataggtgg aggcataagc ctcaaagtga aagtcagctg
    10261 actcttcctc aactgacttg acgacaaagg tttttaattt ttccatatcc tacctccttt
    10321 cttaaaattt ctgccaaccg cccaccctat ttttaattac tttcgctcgg ctcgatacgg
    10381 actgcattta gattggtttc gaatacttct ccaccttcat atcctggaag ccctagatag
    10441 gtttcacgga attcatttga attcatcaaa cctgcgtatt tagatttaaa tccaccttct
    10501 actagatcct tgaatgaaat catgtcagcc atatcaaaga agaccaagag cttgtttcct
    10561 tgtgtccttg ccgtcttcgt gaaatatttt ctattaattt cttcagagaa tacacgttga
    10621 tataatttca tgacgctaga atagtaagct ctatattgtt cttctgtgta gtcacaagta
    10681 aacaattttt cattaattcc atgagcatga taaagttgag atttcagaaa ctccatttct
    10741 tctttagaag cggttgagta atctttgttt aattccataa actcttcacc ttgctcgaga
    10801 taggcaatgc caccaatttc agcaagttcc atcatgctat caactctact cttagcttgt
    10861 ttcttcaaat gttcatctgc tgctttagtt ggtagtttta agaatcctct caactttgaa
    10921 ttccctctgc ctaacttctc ggttaacgca tcaaggttga tatcaattaa ttctgtgatt
    10981 tggtttagtt gacttgtcac gtttaattta ggattttcaa aaacccagac atcgctaaga
    11041 ggtagctcaa tctctacatc atcaatcatg atttcaactc tctctgcagt ccatgatatg
    11101 gttttctttg caaaccaaat ttcaatcagt cgaccatttt cccaacgtgg aacaacgact
    11161 gcaacaccat ctttcagcat agctcttgtt acatttgccc aaaatacaac tggtatttca
    11221 agaggatttg gagagaaaga taaaacattt gcaagatcac tattttcaaa ccactccatc
    11281 ttatcaactc ccgtcggatt tcgagtgatt ctcacatgct taaatcgaac ttgtgcagta
    11341 tctgttgaaa tcttattgta gatattgtct aagtaaatcg aatttcttct ccaataattc
    11401 aaatttcttt gtaaataggt ccttgtggat tttctattgc ttggtctgaa aatcctagca
    11461 aaaacctctc ttaaattatt tatatatttg ttcattcttc acctcaatca aagtaataac
    11521 tcaagtcttc cttgaaattt tcgtagcaga taaaagcatc taactgacta gcaaatacgt
    11581 caatcttttc ttttgctttt tctttatttg gaaatacatt gttattcgca tctatcttga
    11641 cacgaacatt tgcgtggttc caagttgcca caggatcgtc aaagatgatt ttccccatct
    11701 tagctttttc tttatacact tttaaaggat tggataagct cttgaccgtt tgtggaatgt
    11761 cgtgacatat atctccgtag tagtcattaa ttaagcggat aagctctttt gcattccagc
    11821 ggtcatatcc gactgcaact ggtaagattc tattctcact cataaactgc cttaattctt
    11881 caaagatata agcttgatca ttgtagtcca actcatgaac atgaagctgt ccactaagct
    11941 cccactcagc gtatttgtcc ctcagttctt tcggaagtcc ttcaatcgta tgacgtggca
    12001 tgaatttctt gttcaaatac tgacgctctt cgccacgcac gaccataaat gagaccgaac
    12061 aaatgtcatt gacatccgac aagtcaacac caagcacaca gcgagcactc ctctcctcat
    12121 ttccgacaaa caaactctta tcaaacttat ctaaccaacc cttacactct tcattactga
    12181 agtaagcaag atagttatta acagggagat taaatgtttt agccatcagc tcagcctgtt
    12241 gtgctggatc attcttgctc atttcaatat ccttggcaat cgtctccttc tcagtcgtta
    12301 taccgagtaa aggcatagct ttctgccaca tatctggatt gtgaatttca gaaacatcat
    12361 ccagctgata aatccaaggc atgaccgaat gattgacaat cttttcatca agaatatcta
    12421 cccagatgtt gtaatactta tcaaaaagct tgtcccgttt cgtcccattg gtggagatgt
    12481 accaggttat ccaatttttt cgcttgcgac tcgaaccatc attcacaacc ttgatgaagt
    12541 catcatcata agtgtgcact tcatcaaaaa tattgtagtg agcattagta ccatcaagac
    12601 tttcatagtc ggaagtcttg attgacataa gactattagt tgtctcgtac aagatacctt
    12661 gtttagttga ccgtagtatg tcagcctcac gcatatagtg tagcaagctc tcttcgttcg
    12721 acagcatagc tctagaagca ttaaacagat atccagcttg ttcacgactg taagctagaa
    12781 gctgaatatc agcaccccac tcaccgtcaa taatctgacc aacctcacca atggcagaac
    12841 caagggttgt ttttcctgta ccacgaggta caataatagg cacctcatga atgagacgcc
    12901 tttcttcaaa atctttatat tcttcaagtg tatcgggatc tgtttttgta acttcaactg
    12961 tatgataaaa accccacgtt gtttctagcc agaccttctg aggcaaagcc aagtgtaact
    13021 ttccagcaag acctttagtg ttgctgcact cttcctcaat gaactcaatc cgtttgtcaa
    13081 cttcttcttg tttaaagatg tattgttcct tgtacctctc tactcgttta atcgacttca
    13141 tcgtaagttc acaaacacga atcttccctg agtagaccag ctgagcatat ttatcaaaat
    13201 atctcatctc aaccatatcg agccaacttc tcctgaatca tttctttgag gctatcaccc
    13261 tgtggacttt gcttttcaat cgttgacata atctgcatgt ttagcttttg atacttttcc
    13321 attccatcaa gtaaatactt atcaggtagc tcaccgtcat tgatgacttt attgatttcc
    13381 aattggaagt tttcaatcac tttttgatta tgattgtatt gagttttaag atttttcaaa
    13441 cctactgaat cattgtcatt gatttcaagc attttttctt ttggaattaa cttgaaagtc
    13501 ttacgagata gttcaacacg ttcttctctt gtatacttct gccgttgatt tgccagcttt
    13561 tctaactctt tgaattgact ttttgtgata ttcgaccgag tttcttcaaa tatgcctagc
    13621 ttttttcgat acctggtgag ggtagcacga cttattccta gcttttctaa aacttcattg
    13681 attttcaaaa tcatactcct ttcttgtatc aattttcgtc atttttgggg gagaggtata
    13741 taagaggatt gacaccgtta ttattttggg tgtgtgaaaa ttttaaatag gggggatctg
    13801 ataaaaataa aaaattcaaa aaataaaaaa tcaaaataaa ttaatattcc gattttctaa
    13861 atttaaattt attttacttt gaaatgtttt tgtattatga cactcgagac aaagtaattg
    13921 cagattatct tcgttgagag taatagactc atcttgataa ttagtttcat caatctctat
    13981 aatatggtca acaatgctct tgccatgaat taaacgtcca cacatgtcac agcgcatacg
    14041 ctttatactt ctgattctat ttctcaaagt tctccaaggt ttcgagttgt agaatttaat
    14101 ctgccaagtt ctaaaccagt cagagtgttt aggattcttg aatgtcatag cttgaatgat
    14161 tcaactcgga tttctcttgt gtatctgttc atgaacgaaa tcatcttata cattggcttg
    14221 tcccatgcat aaattattga tgtgtcaact agaatctcac tagtcaacga gtacggatac
    14281 ctttttggtc tcatgcttac ctccaacaaa aagagaacag atctagactt gctctccgaa
    14341 tttttcgcat gatacaaata tatcagattc attttgtcaa tactatatct ttttttgaca
    14401 agatttattt ttgagttttg aatttatgta aaatatctct gttgaattag ttatatctta
    14461 tattttatcc aattttgttt catactaaaa aactagcacg gacaacgctt caggccctct
    14521 tcaaaatata aactagaaac ctcctcgtta tggatagttg aaaaaatcaa aaaaatatta
    14581 gaggctaaaa ttactcatct tagtatcaag ttcatcttgc cttacacaaa tataaattag
    14641 tgtaactgct ggacttgaat gattgaataa tgacatcaag tctgcaacgt tcttgtactt
    14701 cttatagtaa tgatagccaa atgtttttcg catcgtgtga gttccgacat tatcgattcc
    14761 taagtcttca gcagctcttt taagaaacca gtataccgtc ttatagctga gcgccttatt
    14821 ctttccgaca cgactctgaa atagatactc atgtaattct ttatctttga caaattccct
    14881 caattcattc ttgagtggcc ttgtcatttt aatgctcttg tatttccctg ttttctgttc
    14941 cctaacttta atatgccaac cttgaacatc tttaaccttt agtttgagaa tatctccgac
    15001 acgaaaacct gtattgattc ccaaaagaaa taacatgtaa tacttttcat tccaagatga
    15061 tagatagtcc ttcatggctt ggatatcatc cttatctcgt aacggttcaa caatattcat
    15121 agttttactc ctttcacaaa aaaaataaag cactaagatt ttctcagtgc tttggatagt
    15181 atcaatctat catattcttt ttgtcaatgc tatacttttt tttgacaagt tacatgaaca
    15241 ataactttgc aagtgtatca agaatgattt cacgtcttct gtaaatctgc ttactgtgcc
    15301 tgtatagata cccagtgtca ccattctcca ttttatgcca aacttgaatc caatcgtacc
    15361 tagtgtgttc tccccatttc aaatgaaaga tttttttatc atcaggttca agtacatcga
    15421 gtagctttga aattgctgtt tgaaagtttt ccagtcttaa aaccatcgga tcgcttgcat
    15481 aagcaactgc taggttctca gacctattta cgaacgtgcc acttccgctt gcaccagtat
    15541 catcaatacc aggaacagtg agatgtttca cttcgtacaa tcgttctaat tcatgtcttc
    15601 tttgaccaat caatttgtca atctgtaagt atttatcatt gagttcaaac tcgagataat
    15661 ctcttcgtgc tgttattagg ttctttttgc ccaaacctta cctcccatat atcttttagt
    15721 tttgacccat aggaaaaact cttctggtgc ctctttttct agaatgtcca ataatgaaca
    15781 ctcgttcccg attttggggg actccgaaat tcttgctgtt aagcacttgc cattccacgt
    15841 tgtaccccag ttcatccaag gttgagataa tggtctcgaa tgtaactcca ttttcgtgat
    15901 tgagcaatcc tttaacattc tcaaggaata gatatttagg tctgagaata gatgcgaacc
    15961 tagcaatttc aaagaacaaa gttcctcgtg tatcttcaaa acctcgtctg tttcctgcaa
    16021 ttgagaaagc ttggcacgga aatcctccac agataatgtc cacacttccg attcctcgaa
    16081 tagattcatc tgatactgct gtgatgtcat gtaattctat ttctcctttc gtattgtgta
    16141 tcgctttata gctttctcta gcaaacttgt caatttcaca aaagccaata catttatggc
    16201 cggcagactc cattcctaaa cgaaaaccgc caattcctgc gaataaatcc aagaatttca
    16261 caacatcacc tcatccccga ctttcacctt gtcatacacg tccttcataa ccacaagcac
    16321 cccttagtca cgatctgtga cctccttttc tacagtaatt gtaaattcac ggtcatttat
    16381 gtttaaaggt agaactaccc ctgtttttga atcgtctttt agcaaatcca atacaatttc
    16441 taaaacttgc ttacctaaaa tcaattgtat ctctaaaata ttttgctcat cttccatcac
    16501 tccacctcct caaaataact atgaaattta cttaaattga caatagcgac ctcttcaaca
    16561 gaatgctttc cgatgtcaaa gtctggatca ttcttcccaa actctttttc tatagctttt
    16621 tcagccagaa aaggcaaatc gaatatactt gccccatttc ttaaagcgag cgcttgaccg
    16681 tatttgttca ctattcgata ccctatatca aacggtctga tttcccttgg gacttttatg
    16741 catttacttt gattcttcat tccttcttca agtgtttgtg tcatcactcc acctcctcaa
    16801 tctcaatccc tgggcaatca aacacccagc cgaacccggc ttcttcaagt tctttgcggg
    16861 tgtgggctat tatttgatgt tctggttcat aagctgaatg aaaaaaccat atatcttttc
    16921 ggtttccaga aataaggtaa ttagtaaaat gtacaccttt caccttcacc aaataccgct
    16981 tctctttttc gacctcgtag ccgaagttgt gcatgttgac gagggtttga ataggatttt
    17041 ctctggtgtt attaatccaa ttattaaact ctctattttc tgatttttta gcctcatccc
    17101 tgaaagcaat ccaatcccaa acattaaatt caaaagaatc cttattctct tcataccaat
    17161 ccgccacaaa ttgctttact ttgactggtt ttggttcatc tagctgttct aagtctttta
    17221 aaactagctg acaaactaca atcgctgcaa tatcaaatga actattctcc agctctttat
    17281 atttctcaat caattcctgc ttattcatct tagtttcctc tataaatcaa ataaactgca
    17341 ataactacct gagacattcc tggcgaatag ccaacccaat catcaaactc cttagatttt
    17401 ggcaaccaat ccttagtagc tcccaaatca tagtctgtag gcttttcatc agcgaagatg
    17461 cattccatcg ctcccataaa cgtcatacca tcttctgcca tttcccaaaa atagtccgcc
    17521 cggtctttca ccgcttgtgg taaatcttgc ttgggaggtt gcggcttccc gtcttctacc
    17581 gtccagttgt atacttcatt aactttttgc tttaactctt ccatcacctt ccaactcctc
    17641 cactttccgt ctcaattctt tattcttttt cctcagcaaa tcgcgctcca gcgctctaat
    17701 ccgtctcttg cgtgcatcgc acggcttcga atactcgatt atcttctctt cgttttgctc
    17761 gatcgtgcgt ttcagtccgt caatctcagc ctgtttatcg tacttcatct tctaaaaatc
    17821 tttcaatagc ttctctgtag gagacttcca ccagaccgtc taagtcgttc agggcttcaa
    17881 tatagtctgg acgaccttgc ccgtactgct ctttcaaaaa ttcaacaaag agatgaattt
    17941 cctgataggt tactccaacc atgtttctta cctcccacta aaaatgtaac gttattgatc
    18001 atctttcttt tcctttcttg ctgcacgttc cccgactaaa tagccgagaa ataaccacag
    18061 aatagccatt ccaaattctt taataagttc aatcattttt ttctcctcct gaaaaagtcg
    18121 ctaaatagta acaatcctta gaaccgtagt caaatcgtgt cgtccgctga ccaatgtgct
    18181 tctgaaatct tggatgagtg atagccgaga aagcccactg atgatcttcc atctgttcaa
    18241 tgagatcatc gacattgtca aacgttccaa ggtaaaactt gcagtgcccg ttgtagacga
    18301 aataaagctc taacatcact ccacctcgac agggtaaaag ttcccaaagg aacctctcaa
    18361 tgccttgcta acctgtaagg ctgccgcccg agaaataaac cgcatggctt tcttctcctc
    18421 ggaacacgaa atatccaagc cagtcacact gataattgca gaccttagaa acggcttatc
    18481 ctctcttgtc ccatgcttta aaataaacat cagccacccc tattctaaaa atattgcttt
    18541 cgcttgtttg tcaaatcatt gaaaaccatc aaatggtctt tatctacacc cttcattagt
    18601 ctggacatga aaggtctgcc atatcttttt tgaatatcgg tagaaatcaa atttgtggta
    18661 atgattgtgt ttgaacgctt attcaagata ttgtagagaa tagtaaatga ccattcgcta
    18721 tctttttcca ttcctaaatc atccaaaacc aagaacttag cactagcaat tttattgacc
    18781 agaaactctt cctgactaaa atcagcttta atcttcatca gcaagtcagt tacgttaata
    18841 aaaatagcaa tctctttcgt gtactcagat agagccttaa ccatagcaaa agccaaatgg
    18901 ctcttacctg ttccagcttc tccttgtaac acgatgttgt tcctagcacc ctcagaccac
    18961 tcacgacaaa tcctctttgc aaaagctagc ttttccgctt ctttttcggt tggtgtttca
    19021 aaattgtcca aagtagcatt tttcaaaatt tcatcataaa gagagaactt ttcaagatag
    19081 tatttcctct ctcgctcatt ctcagcatta gccagttcat tcactctttc ctgattttct
    19141 tcatgaatcc gctcagattc acacatgcga catacaacac tctcggtcct caatatcttt
    19201 atcaaaggga tgttatgctt ttcgcagaac tcttcttgtt gttctgtatt cctacgataa
    19261 gataaggcga tttcctcaaa cacattgtct accatactag ccgacctccg cattcatgcc
    19321 agctagccat ttcagacaag caggcaacca cttgatgaat tggttggtct gctaaaagag
    19381 ttttcttctc gtagcttaac ggataatagt caatctcgaa ctgctcaatt agttctaaaa
    19441 tccccattcg tcccttacct cctgttccga tgttttatcg ttttgttgtc ttgacttctt
    19501 accctcttta tatttacggt cgtcctcatc cacctgctca atcgatgtga agcctttctt
    19561 tttccaactt tcaagaatgg ctattaggta attgaaacta ggtttgtgtg atccggaagt
    19621 tttctcgact gcacggttca acatatcgaa actcattcca tcaagtccca cataatcaag
    19681 taactgttga tgtgacttat cagttagatg gattccgcta tttttcaaat tttcagaaag
    19741 gctggaacta atcatcacct tattattatt tatctctata tctttatcta attctttatc
    19801 tagtgcgtta ccatgcgtta ctgtaacgtt atccataacg ttatcagtaa cgttactttc
    19861 gttgttctgt gcaagtaatt tctgtttttg tcggtgacgt gctgctctat ttcgattttg
    19921 ctcttttatt ttttccatgc cgtcaatgtt ctgatgtttc tcccaattgg gtaacattat
    19981 cactccatcg attttttcaa ccattccaaa cttttcaaaa acttcaagag ccatacgaac
    20041 tgtattcaac ggacggtgga acgtttgtgc aagcatttca tcggtgtata caatgttttt
    20101 agaaatggtt agtacgcctt ttgtattcaa tttgcctgct agtgttataa gtttgatcca
    20161 gattacaata attgcatcac gatcaggcga ggcatcaatt agacacatct tttcatcgtc
    20221 aaaaatatcc gttttgattt ttatccactt gatttcagac ataccgagca ccccacttcc
    20281 tgcgattggc acggtacttc atccgcatat cctcatagat gtgcctgcct tccagctcca
    20341 ttttttcaag cttaagtaga cgattttcag acgatagaat tcgatagtct ttggctagct
    20401 tgttataatc gttcaagtat tccttgatca tgaacatggt atcattatca ttttctagat
    20461 gtaggttaaa gtccgatgtt tcctcgtcag aaatcatttc cctgtttaat ttttctttgg
    20521 tttcaagcca ttcaatcaat tcttccattt cctgacctcc tcattacaaa aatctgattg
    20581 cagactgttt aggttctggc aaagctaacg gctcaggacg caatccttga ggcggttcat
    20641 tgtcgtaggt aaagcccttg aacggacgac gaatattctt gcggatttct tgacgttcag
    20701 cttctctacc acgttcgtaa gcatggttat agcctcgaat aatcatagac gcaaattctt
    20761 gctcttctcg tctttcttct tccttgcgtt gttcctgcaa tttgatatga cggcaagccc
    20821 ctgcaaatcc aagcagtaag gctccaaccc ccatcaactg gtctaaaatc ggtggttcaa
    20881 acatttttat ctccttatcc tctttttgtg ctataatata gtcaaataat tttgctaaga
    20941 ccttgtccag aagcctttta gtaaagttat tatatttgat tagagagcca ttctttgatg
    21001 gctctttttg accatttctt accaggtaat tcctttggaa atccctttaa gtaacgataa
    21061 ttatctgaaa atgtggcata cttaattcct agaaattcgc aggtagtgtt cacatccatc
    21121 aactctggat agtgatcact atctttttct atttcgacta gccttgtgat tgtgtccttg
    21181 ataatagatt taatccattc agatagtgaa agtagaacat tgtccatctt cttcccctcc
    21241 tacccttcgt caaatgagtt caatttcatg attttcatct tggtattagt gcttggctcc
    21301 cacgtcatcc agtaagcaag agcggcatcc gcatgcttct tgggtagcag gtcatagcga
    21361 ctgatattga aatgatcctt aaaatcaatc tcagcttgtc taaagactga ctgagcaaaa
    21421 atcttatccg cataagctgg gctatcaata ccacccagac atgccacaac cctagccttg
    21481 cgctttttca gaagcgactt agcatagctt ggatgaatcg gttgctcact cttgaggtag
    21541 tcgatgtctt caatcatgct agcttgttgc tcacgcaatt tcttttgtcc agtaaataaa
    21601 gcgataaagg catcctcgtc caaatcctca cggataaatc cgccctgctt acgaatagct
    21661 ggcaagacct ccgatgtcac ccaacgcttg aactctttag cttgaggcaa cttgctggat
    21721 aagataagag agtagagacc agattcgttg atgactgtct gatttctcat ctgacctgcc
    21781 gtcgcgattt gcgacgttag cttgtcatct tcatcaacgt gttttgccag agcatctctt
    21841 gaatttacat atccaagaat ctctgctata tctttcccga cgaaccacgg ttcgtcatca
    21901 aacatcactg tacggacttc ctgcccgtga aaattaaaaa tttcgttcat agtattcctc
    21961 tctaaatttg gtataataaa aataaaaaca aggggtgaat aatcgtgtat gtacctataa
    22021 aaccaactgg agatttctca accaatttca cacttagtga ttcctgtaaa atctgtaaaa
    22081 atattacttg tccaacagtt gtgaacgaaa caactcagag tatagataac gatcactatc
    22141 gattttgcgc aactcgctat tgtcaacaat gtaaccatta ttttgttgat gaaatcgaag
    22201 ttacaataac cgttgatagt ttcgcaaata ttgattatca atacgatata ttagatgtaa
    22261 agccagaact tcctagcgac atcccaatat caaaagaatt agcaaaactc tctcctatag
    22321 gcaaagagat atatactcaa gcacttaaag ctgaacaaga aaaacttgat catatagctg
    22381 gtatcggttt tcgcaaatcc ttagaatttt tcgtaaagga ctttgttatc tcttttgaat
    22441 tagaaaataa agataaagtt gctaaaatgc cactgaagca agttattgat aactatattg
    22501 ataatcaaaa tttgaaaaca tttgcgactg caactgttta tataggtaac gatgaaaccc
    22561 actatactaa aaaacatagt gataaggatc ttcaagattt gaaaaaattc cttcatggat
    22621 tcttgcacta tatggaaatg caacttaatc ttttggatgc ttatcagctt cttgataggt
    22681 gagcatagca gtctcgattt tatccaactt ctcagcaata tatgtcacgg tcctcaatat
    22741 ctcgttgagg gctgttcttt ctagttcatt catcttcccc tcctactcca acactttact
    22801 gccaactacc aatcgtttaa cgacaacgtc catctcctta aattcggcat tctctgcaca
    22861 gtagcggaca ctctcgctga tgatgtgaca aatagatacg ccgtactcgt tcgccagctc
    22921 cgtagcaatt tcccaggcat ctttgtcaat ccgtgttact ttttgcgctg cgttgttcat
    22981 agtgttcctt tctagtttta ttttgttcaa gtttcttgaa cttctggttt aaaaaaataa
    23041 tctcctattt ggttatctgg aataagtaac agattacaag ctgttgtaat ttcgttgttt
    23101 ttccaataac gctgattatt taatttaagt gaaatacttc gttctgaaag tttcatagct
    23161 ttagcgaatt ttttcttgct attaaaaatt tcagtaattc ttccattcaa ttttgaataa
    23221 tcaaatttca tttattcccc tttctatctt ttgttcaagt tatttgaact tttgtagtta
    23281 taattctact ccttattctt tgccttgtca atacataagt tcattttttt tgaacttttt
    23341 gctttttcac ttgaactttt gttcaaatag atatataatt actattgaga acggagtgtt
    23401 aaatatgaaa actacaacat ctttacgact aaaacaaatt ctgtctgaaa gaaatcttag
    23461 acaagtagat atcttgaata gttctttacc acttcaaaag gaacttggta tcaaaatggg
    23521 taagagtgct ttgtcacaat atgtttcagg aaagtcttct cctgatcaag acaaacttgt
    23581 tttattatct aaaacattag gggtctccga agcctggtta atgggatata atgttcctat
    23641 gtcagacgat actcctgtcc aagaactgaa aatacctact tcccctcttg ttcagaaaat
    23701 aactgaaaaa gctgtacagt tgtcaactcc aagaaaacaa aaagttctga actatgctaa
    23761 tgaacaatta aaagagcaga ataataaagt gattatgatt gaggaaaatc tttttgaata
    23821 ccgtgttttt gaaaaacttt cagctggtac tgggttctca tacttcaacg atgggaacta
    23881 tgacactgtt ttttatgaca aagacctaga ccacgatttt gcttcttggg ttttcggaga
    23941 ttccatggaa cctaagtata tgaatggaga ggttgttctt atcaaagaaa caggttttga
    24001 ctacgatggt gccatttatg cagttgattg ggatggtcaa acttatatca agaaagtcta
    24061 taaagaaaaa gacggtctca gactcgtctc tatcaataac aaatataaag ataaattcgc
    24121 accatttgaa gaagatccaa gaatcattgg aaaaatagtc ggaaacttca tgccgattga
    24181 aaattaaaag gagaaactta tgaaaatagg aatgagaaaa ccaagcccga tcagaagttt
    24241 aaaagctaga actactagta aatggaaaag acaggctaaa aaagccctta tccctggcta
    24301 tggtaagaaa gggatgggat gggttaaaaa tccaaagaaa gccatgtata acaaagtcta
    24361 tcataagaca acctttggac tttcagattt gtttaaatca tctaaaaagc gaaaaaagaa
    24421 agtagtcaac aacaaacagc aatctattct tgcctcgaac ggcaaaaagc aacacacgtc
    24481 aaaagaatat aaagaagctg gacttgtctt tatggtttta ggtgctatat tcctattttt
    24541 atttctacct ctcggcttct tcttgtttat tactggtttt ataacttaca ttattggtct
    24601 tttaactgca aatcgagaga aaaagaagaa agttgaaaat tacagtccac agattgatac
    24661 aattgttttc cgagatgatt tcttattaat gggaacaaat tatcatcaag aagaagctga
    24721 gattgcagct gattttcttt ccaagggtgt ccattatttt gggaaagata ataagagttt
    24781 gaaatcttat atgcttgaaa catataaacc agtttataaa tacaataaat taaaaacagt
    24841 agatgttcat ctattgccgg agccatcaaa tcctcatgat aaaaatgctg tcaaggtttt
    24901 agtgaataat atctttgtcg gatacttacc agctatgatt gcaacacaag tttcatccta
    24961 catttctaat ccaaattaca gatatgatgc aatccttaca ggtagaggag gaccatataa
    25021 aactctcaat atcgaaactg agagagtcgt ttctcgtaaa agtgacttaa cttactattt
    25081 agatttaaca gtatggcgtc tcgctaaaaa ataaaaaaat ccccacactc tccatcgcca
    25141 aactttgagt gtgaggatat ccagtataat aaaaggcatt aaaaagccct ctttactata
    25201 ccctatttta caccatgaaa ggggtgatgt caatattctc aatgtttaga ccttgtccag
    25261 aagccgataa acaaggagaa tacaatgaaa tataataaaa caaaataccc aaatatctat
    25321 tactatgaga ctgcaaaagg caagcgttac tatgtcagac gttctttttt cttccgaggt
    25381 aaaaaaagag aaaaaagtaa aagtggtttc acaactctcc ctcaagctcg tgcagccttg
    25441 gtagagcttg agcaacaaat acaagaacaa gaattaggta tcaatacgaa tctaacgctt
    25501 gatcagtatt gggatatcta ttctgaaaag agattgtcaa cagggcgctg gaatgacact
    25561 tcctactacc tcaatgataa cctctataag aatcatatca aggcaaagtt tggttctacc
    25621 ctgcttaaaa atttggatag aaatgagtat gaactcttta tcgctgaaaa gttgcagaac
    25681 cataccagat acactgttca aaccctcaat tccagcttca tggcattgct gaatgatgcc
    25741 gtcaaaaatg gaaatctgct ctcaaatcgc ttgaaaggtg ttttcatcgg ccagagtgat
    25801 atccctgctg caaacaagaa agtgactctc aaagagttca agacttggat agcaaaggca
    25861 gaagagatta tgccaaaaca attctacgct ctgacctatc tgacaatttt tggattgaga
    25921 agaggagaag tctttggatt gcgtccaatg gacatcactc agaacgacag cggacgggct
    25981 atactgcatc ttagagacag tcgaagcaac cagaccttaa aagggaaagg agggcttaaa
    26041 acgaaggatt cagagcgata tgtctgcctt gatgatatcg gaacagacct gatctattat
    26101 ctgatagctg aagcttctaa gattaagcga aagttaggaa ttatcaagga acagcacaag
    26161 gattatataa ctatcaacga gaaaggtggc ctcatcaatc caaatcagct aaatagaaac
    26221 ttcaatctag tgaatgaagc aacaggattg catgtaacac ctcacatgat gcgccacttc
    26281 ttcacgactc aaagcattat tgcaggggtt ccgcttgaac aattaagcca ggcgctgggg
    26341 catacaaagg tttatatgac ggatcgttac aatcaagtag aggacgaact tgctgaagcg
    26401 acaacagacc tatttcttag t
//
LOCUS       DBERAE010000028        25778 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.28, whole genome shotgun sequence.
ACCESSION   DBERAE010000028 DBERAE010000000
VERSION     DBERAE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.28"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(301..546)
                     /locus_tag="ACL70N_001380"
     CDS             complement(301..546)
                     /locus_tag="ACL70N_001380"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS0590168.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            930..1169
                     /locus_tag="ACL70N_001381"
     CDS             930..1169
                     /locus_tag="ACL70N_001381"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0590169.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(1279..1482)
                     /locus_tag="ACL70N_001382"
     CDS             complement(1279..1482)
                     /locus_tag="ACL70N_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS0590170.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(1513..2121)
                     /locus_tag="ACL70N_001383"
     CDS             complement(1513..2121)
                     /locus_tag="ACL70N_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0590171.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(2152..2322)
                     /locus_tag="ACL70N_001384"
     CDS             complement(2152..2322)
                     /locus_tag="ACL70N_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGS0590172.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(2334..2900)
                     /gene="amaP"
                     /locus_tag="ACL70N_001385"
     CDS             complement(2334..2900)
                     /gene="amaP"
                     /locus_tag="ACL70N_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGS0590173.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2984..3148)
                     /locus_tag="ACL70N_001386"
     CDS             complement(2984..3148)
                     /locus_tag="ACL70N_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS0590174.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            3591..5072
                     /gene="mgaSpn"
                     /locus_tag="ACL70N_001387"
                     /gene_synonym="mgrA"
     CDS             3591..5072
                     /gene="mgaSpn"
                     /locus_tag="ACL70N_001387"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGS0590175.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5434..6435
                     /locus_tag="ACL70N_001388"
     CDS             5434..6435
                     /locus_tag="ACL70N_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0590176.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            6586..7503
                     /locus_tag="ACL70N_001389"
     CDS             6586..7503
                     /locus_tag="ACL70N_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590177.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            7514..8404
                     /locus_tag="ACL70N_001390"
     CDS             7514..8404
                     /locus_tag="ACL70N_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0590178.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            8433..10049
                     /locus_tag="ACL70N_001391"
     CDS             8433..10049
                     /locus_tag="ACL70N_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0590179.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            10059..11378
                     /locus_tag="ACL70N_001392"
     CDS             10059..11378
                     /locus_tag="ACL70N_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS0590180.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(11588..11660)
                     /locus_tag="ACL70N_001393"
     tRNA            complement(11588..11660)
                     /locus_tag="ACL70N_001393"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11625..11627),aa:Lys,seq:ctt)
     gene            complement(11925..13196)
                     /locus_tag="ACL70N_001394"
     CDS             complement(11925..13196)
                     /locus_tag="ACL70N_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGS0590181.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            13466..13666
                     /locus_tag="ACL70N_001395"
     CDS             13466..13666
                     /locus_tag="ACL70N_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590182.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            13870..14049
                     /locus_tag="ACL70N_001396"
     CDS             13870..14049
                     /locus_tag="ACL70N_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590183.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            14186..14365
                     /locus_tag="ACL70N_001397"
     CDS             14186..14365
                     /locus_tag="ACL70N_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGS0590184.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            14402..14854
                     /locus_tag="ACL70N_001398"
     CDS             14402..14854
                     /locus_tag="ACL70N_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGS0590185.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            15145..15615
                     /locus_tag="ACL70N_001399"
     CDS             15145..15615
                     /locus_tag="ACL70N_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGS0590186.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            15671..16213
                     /locus_tag="ACL70N_001400"
     CDS             15671..16213
                     /locus_tag="ACL70N_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590187.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFEDLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            16263..16427
                     /locus_tag="ACL70N_001401"
     CDS             16263..16427
                     /locus_tag="ACL70N_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HGS0590188.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGKSVRENLI"
     gene            16537..17571
                     /locus_tag="ACL70N_001402"
     CDS             16537..17571
                     /locus_tag="ACL70N_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0590189.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            17573..19816
                     /locus_tag="ACL70N_001403"
     CDS             17573..19816
                     /locus_tag="ACL70N_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS0590190.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            19867..20886
                     /locus_tag="ACL70N_001404"
     CDS             19867..20886
                     /locus_tag="ACL70N_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HGS0590191.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            20899..21849
                     /gene="prmA"
                     /locus_tag="ACL70N_001405"
     CDS             20899..21849
                     /gene="prmA"
                     /locus_tag="ACL70N_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGS0590192.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            21851..22594
                     /locus_tag="ACL70N_001406"
     CDS             21851..22594
                     /locus_tag="ACL70N_001406"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGS0590193.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            22605..24401
                     /gene="pepF"
                     /locus_tag="ACL70N_001407"
     CDS             22605..24401
                     /gene="pepF"
                     /locus_tag="ACL70N_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS0590194.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(24461..24733)
                     /locus_tag="ACL70N_001408"
                     /pseudo
     CDS             complement(24461..24733)
                     /locus_tag="ACL70N_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            24721..24903
                     /locus_tag="ACL70N_001409"
                     /pseudo
     CDS             24721..24903
                     /locus_tag="ACL70N_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
     gene            complement(24928..25101)
                     /locus_tag="ACL70N_001410"
     CDS             complement(24928..25101)
                     /locus_tag="ACL70N_001410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590195.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSNHTYGKVKLTWFEEI
                     FEEYHTKKPCSSR"
     gene            complement(25113..25646)
                     /gene="queF"
                     /locus_tag="ACL70N_001411"
     CDS             complement(25113..25646)
                     /gene="queF"
                     /locus_tag="ACL70N_001411"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGS0590196.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISINPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         8236 a         4371 c         5232 g         7939 t
ORIGIN      
        1 ataatttatt tcatattttg taaggtcagt gtgaaaatat ttaaatagac ttcctgtaaa
       61 aactggattt aacgccctcc atttgtcaaa ttaagctaga cagtcttacc aactcagaaa
      121 atacctgatg aggtatttgg tatccaaagg atttaggtgg gatgtgattt cttgaggctg
      181 ggaaaaagtc tttaaaatta aaaaatgtat aatatcaggt gttggaaaaa ctttgatact
      241 atgcgtttta ttgtgggaat atttatttca ttttctcctg aaattgagtt tttacccagc
      301 ctaaaattct tgactgactt cgttgaaatc tgtctgcttt ggcaagtcat gacaccttaa
      361 aagtctattt gaatgttcgt tgagacaccg ctgtcttgga catcctagat tcgcaaaaaa
      421 gctctcacta tcgtgatgat tggaaatatc tttccatttt gaaaactctt ttccacagtc
      481 aaacgtaata gatttaaaga ggttcactag aaattgtgcc agccaccctt ggatggattc
      541 tgccatatcc tttgccttac gactcttggt cttcaaactg acaatcaatt gactatacct
      601 gttcgctcac aaataggaga gaacttttta cgaaaatcta atgaatatgc cacaagaaca
      661 ttataccgca acgtgtacta tttttggttc attttactat agaaactatt gaagcacctg
      721 tacgaaaata tagtagattg aaactagaat agtacacctc tacttctaaa acattgttag
      781 aaatcgattt gactgtcccg atcgattcgt cctgttatta tttcatttta ctatacatta
      841 tgaaaaaggg gagatagaaa gcaaacagcc ttgaaatcaa tgttgactgc gattatgaac
      901 ctgaatcagc ccctcaaaag ggactgtata tgaatgaacg ttaccagtgt ttaaaaacta
      961 aagaatatca ggcactttta tcttccaagg gtagacaaat tttcgctaaa cgtaagattg
     1021 atatgaaatc tgtctttggg cagataaagg tttgtttggg ttataagaga tgtcatctga
     1081 gaggtaagcg tcaagtgaga attgacatgg gattcatact catggccaac aacctgctga
     1141 aatataataa gagaaagagg caaaattaaa aagctagagt tccgcaattg ggaatctcta
     1201 gctttttgtt ttctgagaat catcttgact cagactcttt tgactaatgt taccaaaaag
     1261 ataaagtaac ttttaacctt atttatcgtc gccactcaac atgtttttaa caccttctac
     1321 agcaccttct acagcgtctt tagcgtcttc ggcaacttct tttactttag aaacaacttt
     1381 ttcagctgct ccttcttttt ccattttttc atcaccgatg gctttcccaa caccttcttt
     1441 aatagaacct ttagcttgat ttaatttttc ttctactgac atgataattt ctcctgttat
     1501 atttatttta tcttagttta cacgagtgtt ttcgtgagat actacaccat ttgctgcacc
     1561 tttaacagct tctacacctt cgctaacttt ttcttgaaca gttgagaaac cagatccaag
     1621 accagattta gctttttcga attgttctga agtgaattct cctgttgatt cagcaacgtc
     1681 agatacgcga tcttgaaggc ttactgagtc tgcttcatgc tgttctttag ttttgatgtc
     1741 gacaacgttt acgttgattt caacaatttc caagtcagtc attttagcaa cttctgaaga
     1801 tacgatttct ctgatttctg aatataaagc tggaacattt ttttggtact caacaataac
     1861 gtttaagtca actgcaactt gtgttttacc aacttctacg ttaacaccac ttgttacgtc
     1921 atcgctgtta acgatttttt ctttaagatt tgagaagaaa ccaccatcga ttcccaaaag
     1981 acctgaaacg ttttctagtg aaagaccaat gattttttgg ataactttat cttcgtaagt
     2041 aagttcccct ttgatttcgt gagctacaac agtagcatct ttcttttcta cgttagtatt
     2101 tgtgtttttt tcgtttgaca tatgaaactc ctttaattaa attagtaatt tttatttatc
     2161 tatatagttt ttttcgatat ataatccagc tgcaactccc agtgctccta aaatcaatac
     2221 aaatattgtt ttgaagaagc caaaggagac aatcaaacaa gccagaaata cgcctatgag
     2281 accagcgata attggatatc gatattgttt aagccattcc attttttact tccttacttc
     2341 acacgactaa cagtcttttt gttttgaggt tttggttggt aattttttac tgcaacttca
     2401 agttttactt gacgctcaat accaaaaaac tgcttcaatc cattagttat ttcattttga
     2461 attatttggc atctgtcagc gatgttgtct gaaggaagaa ttttaccttc tacatgaacg
     2521 aaacatttat tttttcgtaa atttacatga acagttgggt tcttgatcaa tctatgatca
     2581 ctcaccaaac ttctaacaaa accttcgatt gccgaattct ttaattttaa tgtatcgttt
     2641 ttagtttcaa gttggatttc caagtaacgt ttaggataaa acatcacaac taaaatggat
     2701 aataaaacta aagttgatag aaccactgtc ccccaaaaga catatctagc aagatagaat
     2761 tcaactacgg agttctgtct ccagctaagt agatgaatac ctagatcact aacttgatga
     2821 taatctatca aaacaggaag gaaaattgtc aagattaaaa tacagaaaat aatgaaacat
     2881 attttctttg cttttgacat atacaatcct ttcgatttaa catttaaact atttttcccg
     2941 tcattgattt aaaaatagtt tgctaacttt actggcgaaa agtttacttt ctacctgtaa
     3001 agaatgacac tacagtaatc acaatcgctg cacctacaat agatgggagc aaagccattc
     3061 cagcgattga tggaccccaa ctacctaaaa gagattgtcc tgcatatgcc ccgactaaac
     3121 cagcgaatac atttgcgatg attcccatag aactactttt ttagtgattt tacctgccaa
     3181 gagaccaata agacctccag caataattga tcacaacact gcctaccctc cttttttatt
     3241 ttaatatcaa aaaatcaatt tctttgatta atactattat ataactttaa tatagaaaag
     3301 tcaattattt cgattgttat tattatataa ttttaaaaaa tcaaattctt taattgttgc
     3361 tattatataa tttttaaaat taaaaatata atctttagac ttgaatttga ttctgtattc
     3421 acgccctcaa tagacggtaa aataagaaaa ttgtttatat attgtctccg tagtgttatt
     3481 atacgaaata aaagatttta ggaaaagtcg ttatatcatg ctatacctat tctttgtggt
     3541 ataattgcaa gaggtttaat ccgataattt ataaagagag aaagatattc atgagagatt
     3601 tattatctaa aaaaagtcat aggcaattag aattattaga attattattt gaacataaac
     3661 gttggtttca tcgttctgaa ctagcagagt tattaaattg tacagaacgt gcagtcaaag
     3721 atgatctatc ccatgttaaa tctgcttttc ctgacttgat ttttcattct tctactaatg
     3781 gtatacgcat tattaatacc gatgatagtg atattgaaat ggtttaccat catttcttta
     3841 aacattcaac tcatttttcg attttagaat tcatcttctt taatgaaggt tgtcaagctg
     3901 agagtatttg taaagaattt tatatcagtt catcttcgct ctatcgtatt attagccaaa
     3961 tcaataaagt gattaaaagg caatttcaat ttgaagtcag tctgacccct gttcaaatca
     4021 ttggaaatga gagagacatt cgttactttt ttgcacaata tttttcagaa aaatattatt
     4081 tcctagaatg gccatttgaa aatttttcat cagagccact atctcaattg ttagaattgg
     4141 tttataagga aacaagcttt ccaatgaatt tgtcaacgca tagaatgcta aagttgctcc
     4201 tagttacgaa cctatataga ataaagtttg gtcattttat ggaagtagat aaagattctt
     4261 ttaacgacca aagtttggat tttttaatgc aggcagaagg aatagaaggt gttgctcaga
     4321 gttttgaatc agaatacaat atctctttag atgaagaagt tgtttgccaa ttatttgtgt
     4381 cttactttca aaaaatgttt ttcatagatg aaagtctctt tatgaaatgc gtaaaaaagg
     4441 atagttatgt tgaaaaatct taccatctat tgagtgattt tattgatcag atttcagtca
     4501 agtatcagat tgaaatggag aataaggata atctgatttg gcatctgcat aataccgcac
     4561 atctgtatcg tcaagagttg tttactgagt ttattttatt tgatcaaaaa gggaatacaa
     4621 tcaggaactt tcaaaatatt tttccaaaat ttgtttcaga tataaaaaaa gagctttctc
     4681 actatttaga gactcttgag gtttgttcta gttcaatgat ggtaaatcat ctatcttata
     4741 ccttcatcac tcataccaaa catttggtga ttaatttgct acaaaatcag cctaaactaa
     4801 aggttttagt tatgagtaat tttgatcagt atcatgcaaa attcgttgca gagacacttt
     4861 cttattactg tagcaataat tttgaactgg aagtttggac tgaattagaa ttatcaaagg
     4921 aatctttaga agattcacct tatgatatca ttatttctaa ttttattatt cctcctattg
     4981 aaaataagag actcatctat tcaaataata taaacacggt ctcactcata tacttgttaa
     5041 atgccatgat gtttattcga ttagatgagt aaccaaaaat aacaaaaaaa cgctatttcg
     5101 cgtttgaact gtacctcaaa agttagacag aaaaaatcta atttttgggg tgtttttgtt
     5161 aagaaaagac cttcaatcat ttaagcaaaa tgtacatcta gatttatagc cctctaaaac
     5221 tcttgctttt tttgtagaag atacgaaaaa agccataaaa ccaaggcttt tcctgtttta
     5281 tgtagatgtt tacacatgaa aattgaagta ttttcaaaag ctaattggag tgattttatt
     5341 catgatggga taaatgatct ggccaaaaat gattgagaaa tagttgctta aaaagcattt
     5401 gcatgatact atatattgaa aggaggtgat aatatggtag aacaaagaaa atcaattacc
     5461 atgaaagatg ttgctttaga agcaggagtt agtgttggaa ctgtttcacg tgtaattaat
     5521 aaagaaaaag gcattaaaga agtaactttg aaaaaagtgg aacaagcgat taaaactttg
     5581 aattacattc cagattacta tgctagagga atgaaaaaaa atcgaacaga aacgattgca
     5641 atcattgtac caagtatctg gcatcccttc ttttcagaat ttgctatgca tgtggaaaat
     5701 gaagtctata agagaaataa caaattactc ttatgttcta taaatggtac aaatagagag
     5761 caagactatc tggagatgtt gcgtcataat aaagttgatg gagtggttgc cattacctat
     5821 agtccaattg aacattactt gacgtcagga attccctttg ttagtattga ccgcacatac
     5881 tcagatattg ccattccttg tgtttcatca gataatgatg caggtggaag agaagcagct
     5941 aaacaattaa ttagtaaagg atgtcagcat ttagcctttg tgggcggaca taatacaacc
     6001 attaatgaaa ccaaacgtcg tagaatttca tttgaaaagt atgtccaaga gcataaaata
     6061 cctcttagta tttttgattt ggatgagaca gttactgact attatggaaa gctagagagt
     6121 ttcttggaag aaaattcttc tatagatgga atttttacaa tcaacgattt tacagctttg
     6181 gatgtgattg aaatactaga aaaaaatggc aaacgtattc ctcatgatgt ccaaattatt
     6241 ggatacgatg gaattaaaat ggctggagat agagattatc tactttcaac tattgaacaa
     6301 ccattggaag aaatggcaaa agaagcggtt cgtattttgt ttgatataat tgatggaaag
     6361 actgttaatt tgcagacaat cctaccagta aaatttgttg aaggaaaaac aacaaaaaat
     6421 gaaaataagt cttgacagaa agcgctatca atgatagaat gaattcagat aaaaagattt
     6481 atttttaaaa caaaaatgaa acgtttcaaa aaaagaaata aaaagacagc gccaagcgct
     6541 atcttttata gaaaaaatga aacgtttcaa aaaaaggagg ttgctatgaa tagcaaagcg
     6601 aagcaagttt ctctttggga aagaatcaag aaacaaaaac tcttgttatt gatgactgtc
     6661 cccggtttag ttttaacctt tatctttaaa tacatcccta tgtatggggt tttaatcgca
     6721 tttaaagatt acaatccttt aaaaggaatt ttagggagtg attggattgg tttttctgag
     6781 tttacaaaat tcatatcctc tcccaacttt ggtatcttgt tagccaacac attaaaatta
     6841 agtatctatg gtttattgct tggcttttta ccaccaatca ttcttgcgat tatgctcaat
     6901 caactcttga gtgaaaaagt caaaaaacga attcagctca ttttatacgc accaaacttt
     6961 atctcagtcg ttgttattgt cggtatgatt ttcctcttct tttcagtggg aggaccaatc
     7021 aacaattttc tttctatgtt tggaatgaag gctgacttct tgacaaatcc agacttcttt
     7081 agacccttat acatctttag tggtatctgg caaggaatgg gctgggcttc aacgctctac
     7141 acggcaacat tggtaaatgt agatccagcc ttagtagaag cagctcgact ggatggagcc
     7201 aatatcttcc aacgaatctg gcacattgat attccagctc ttaagcctat tatggttatc
     7261 caatttgttt tagctgcagg tggaattatg aatgtcggat atgaaaaagc attcttgatg
     7321 cagacatcgt taaatttgcc aacttctgaa attatctcga catatgtcta taaagttggt
     7381 cttgtatcag gagactattc ttactcaaca gcggttggtt tgtttaatgc agtgattaac
     7441 gtagtattgc ttgttgcagt taaccaaatc gttaaacgca tgaataatgg tgaaggaatt
     7501 taaggaggaa agtatgaaaa attcgattat ggatacaaaa tttgatagac gtatcttact
     7561 cttaaataaa atcattattg tctttatcgt tttgatgact ttgcttcctt tactttatat
     7621 cgtcgtagca tcctttatgg atcctaaggt tctggttagt agagggatta gctttaatcc
     7681 agccgattgg actgtagaag gttaccagcg tgtattcagt gaccaatcta ttctaagagg
     7741 ttttatcaat tctctactat actcttttgg atttgcagct ttaacagtat tgctatctgt
     7801 gtttacagct tatcctcttt ctaagaaaga cttggttgga cgtcgttgga ttaactactt
     7861 cttgattgtg actatgttct ttggtggtgg tttagtccca acttacttgc tcgtaaaaga
     7921 attgggaatg ctcaatactc catgggctat cattgttcca ggtgctgtca atgtttggaa
     7981 tattattctt gctagggcct atttccaagg attgcctgaa gaattagttg aagctgctgt
     8041 cattgatgga gcgaatgact tgcagatttt ctttaaaatc atgcttcctc ttgcaaaacc
     8101 aattatgttt gttctcttcc tctatgcttt tgtaggacag tggaactcat actttgatgc
     8161 aatgatttat atcaaggatc caaacttgga accattgcaa cttgtacttc gtaaaattct
     8221 cattcagagc caaccaggtc aagacatgat tggagcacaa gcggctatga atgaaatgaa
     8281 acgtttagct gaattgatta aatacgcaac tattgtcatt tccagcttgc cattgattgt
     8341 tatgtatcca ttcttccaaa aatactttga taaaggaatt atggctggtt cacttaaagg
     8401 ataaaaaaag aaaaaataaa aggagttttc tcatgaaatt caaaacattc tcaaaatcag
     8461 cagttttgtt gacagctagt ttagcagtac ttgcagcctg tggctcaaaa aatacagctt
     8521 caagtccaga ttataagttg gaaggtgtaa cattcccgct tcaagaaaag aaaacattga
     8581 agtttatgac agccagttca ccgttatctc ctaaagaccc aaatgaaaag ttaattttgc
     8641 aacgtttgga gaaggaaact ggcgttcata ttgactggac caactaccaa tccgactttg
     8701 cagaaaaacg taacttggat atttctagtg gtgatttacc agatgctatc cacaacgacg
     8761 gagcttcaga tgtggacttg atgaactggg ctaaaaaagg tgttattatt ccagttgaaa
     8821 atttgattga taaatacatg ccaaatctta agaaaatttt ggatgagaaa ccagagtaca
     8881 aggccttgat gacagcacct gatgggcaca tttactcatt cccatggatt gaagagcttg
     8941 gagatggtaa agagtctatt cacagcgtca acgatatggc ttggattaac aaagattggc
     9001 ttaagaaact tggtcttgaa atgccaaaaa ctactgatga tttgattaaa gtcctagaag
     9061 ctttcaaaaa cggggatcca aatggaaatg gagaggctga tgaaattcca ttttcattta
     9121 ttagtggtaa cggaaacgaa gattttaaat tcctatttgc tgcatttggt ataggggata
     9181 acgatgatca tttagtagta ggaaatgatg gcaaagttga tttcacagca gataacgata
     9241 actataaaga aggtgtcaaa tttatccgtc aattgcaaga aaaaggcttg attgataaag
     9301 aagctttcga acatgattgg aatagttaca ttgctaaagg tcatgatcag aaatttggtg
     9361 tttactttac atgggataag aataatgtta ctggaagtaa cgaaagttat gatgttttac
     9421 cagtacttgc tggaccaagt ggtcaaaaac acgtagctcg tacaaacggt atgggatttg
     9481 cacgtgacaa gatggttatt accagtgtaa acaaaaacct agaattgaca gctaaatgga
     9541 ttgatgcaca atacgctcca ctccaatctg tgcaaaataa ctggggaact tacggagatg
     9601 acaaacaaca aaacattttt gaattggatc aagcgtcaaa tagtctaaaa cacttaccac
     9661 taaacggaac tgcaccagca gaacttcgtc aaaagactga agtaggagga ccactagcta
     9721 ttctagattc atactatggt aaagtaacaa ccatgcctga tgatgccaaa tggcgtttgg
     9781 atcttatcaa agaatattat gttccttaca tgagcaatga caataactat ccaagagtct
     9841 ttatgacaca ggaagatttg gacaagattg cccatatcga agcagatatg aatgactata
     9901 tctaccgtaa acgtgctgaa tggattgtaa atggcaatat tgatactgag tgggatgatt
     9961 acaagaaaga acttgaaaaa tacggacttt ctgattacct cgctattaaa caaaaatact
    10021 acgatcaata ccaagcaaac aaaaactaga ggttgattat gggagataag aaatacacag
    10081 tagaaaaagc caatcgtttt atagcagaaa ataaacatct cgttaatact caatataagc
    10141 ctgaagaaca tttttcagct gagattggtt ggatcaatga tccaaatgga tttgtctatt
    10201 ttcgtggaga ataccatctc ttttatcaat tctatccata tgatagtgtt tgggggccta
    10261 tgcactgggg acatgctaaa agtaaggact tggtgacttg ggagcacttg ccagtggcac
    10321 ttgctcctga ccaagattat gaccgaaatg gttgtttctc aggctctgcc attgtcaagg
    10381 atgatcgcct ctggctcatg tacactggac atatcgaaga agaaaccggt gtccgccaag
    10441 tgcaaaatat ggcattttca gatgacggga ttcactttga aaagattgaa caaaatccag
    10501 ttgcaactgg atcagacttg ccagatgagt tgattgctgc tgattttcgt gatccaaaac
    10561 tctttgaaaa agatggacgc tattactccg tagtagctgc caaacacaag aataatgtgg
    10621 gctgtatcgt tctactaggg tccgataacc tagtagaatg gcagttcgaa tccatctttt
    10681 taaaaggggt agaacaccaa ggctttatgt gggaatgccc agattacttc gagttagatg
    10741 ggaaagattg ccttattatg tcacccatgc gttatcagcg tgagggagac tcatatcata
    10801 acatcaactc atcgcttttg ttcacgggta aggtagattg gggagaaaaa tgttttatcc
    10861 cagaatcagt tcaagaaatt gatcatggcc aagacttcta tgcgcctcaa acattgttgg
    10921 acgatcaaaa tcgtcgtatc ctgattgctt ggatgcagac atgggggcgt acccttccaa
    10981 cccatgacca agaacacaaa tgggcatgtg ccatgacttt acctagaatt ttaagattgg
    11041 aagatggcaa actaagacaa ttccctgtta aaaaaggcca atatcaaatc caaatagata
    11101 aagattgtca ttaccactta ggaaatgata tagattatct tgaatttggt tatgatagta
    11161 atgcgcagca agtttacatt gatcgtagcc atcttattca aaaaattcta ggtgaagaag
    11221 aacaggacac tagtcgacgg tatgtagata ttgaagctaa agaattggaa gttgttctag
    11281 ataaaaattc catcgagatt tttgtcaatc aaggtgaagc aagcttgact gcaacttatt
    11341 acttaacggt gccagctgag ctatcacgaa ttgattaaaa attaagttat ttctcctaaa
    11401 gaaaaagttc tctttctaaa atagtggaaa gaggactttt tgtgttttgg gtatataagc
    11461 ttagtttatg gtatttgtaa aattggtgtt ggattatgat ttaagctagt tttctaaaga
    11521 atttgaaaaa aattttattt aagcaaaaaa aacccttggt tccaaggctt ttcctgttgt
    11581 atttatatgc cccctacagg gatcgaacct gtgacccacg gattaagagt ccgctgctct
    11641 gccagctgag ctaaggaggc aaagaaaaaa gctgtattgg tgccgaaact tcacggtttg
    11701 tattgaaccc gcgcaattaa gcaggtgggc aactcgctct aactgaagct gtttccgtgt
    11761 gagacggcct acatgctgtt agaagacttt tgtttcccta ataatacaaa aaatagtcgg
    11821 tcaacactta agtgtgaagt cgtacaccac agcgtttcta tacttatatg ataccacttt
    11881 ttcaaaaaaa atcaagagga aagtgcaatt ttttgaaaag gatttcagat ttttcgcaaa
    11941 cggtcgatag cttcctttct ttgagccaaa gcccgttcat atttaccagt atcttctgct
    12001 tggaaatagt gatgattacg aattttttct ggcagatagt cttgcttgac ccaatttcca
    12061 ggatagttgt gtggatagag atagtcttgg gcattcccca gttccttgct tccactgtag
    12121 tgcccatcac gtaggtgtcg cggaataggc aagtgccctg atgttttgag gtcagcaagt
    12181 gccttatcca tagctacata ggctgagttg gattttggag aaagggccaa atcaatcacg
    12241 acattggcaa tgagaatgcg ggcttctggg aacccaatct tctgggcagc atccagagca
    12301 gtcacggtat gaatctgggc ctcaggattg gctaagccga tatcttcata ggcgataaca
    12361 gtcaagcgac gagcgagact aggcagatcc ccagcctcaa tcaagcgggc agtatagtgg
    12421 agactggcat ccacatctga gccacgaata gacttttgca gggcagatag aacatcatag
    12481 tgaccgtctc catccttgtc catagtgatg tagcttctct gaagactatt ttccatgatg
    12541 tctaaggtga tgtggcgaat gccctcgtca ttctcagggg tagagagaac agctaagtcc
    12601 agtgagttaa aggcagagcg aaggtctccg tttgtagagg ttgcgatgaa atccagcgca
    12661 tcctcatcta gttctattgg aaaatcaaaa ccacgttcag ggttacttag agctatctgc
    12721 agggcctctt tgacgtcttg gttagacaga ggttccaact cgaaaatttg aactcggcta
    12781 cgaatggcag gagtgacaga gaagaaagga ttttcagtcg ttgctccaat catgatgacc
    12841 agtccacttt ccaagagagg caagaggaag tcttgcttgg tcttatctag tcgatgaatt
    12901 tcgtctagca ataggacgag accaccagaa aatttagctt cttccgagat ttcttgcagt
    12961 cgctttttac tatcaactgt cgcattgaaa gttcgaaagg catacttggt cgttccagcg
    13021 atggcagagg caatactggt tttgccgatt ccaggagggc catatagaat catggaggac
    13081 aggcggttgg cttccaccat gcggcggatg atttttccag gtccgaccag atgctcctga
    13141 ccgatgacct ggtcgatggt tttagggcgc atgcgaagcg cgagattgtc tggcatagca
    13201 gtcctttcta gcgtggattt gagtagaatg actcatctac tatatcttac tatgtccatt
    13261 ctagcctatt agttgtgata tttcaatggt tttgtaataa tcagggagtg agatagaatc
    13321 ttttttacta tttaatttaa tgaggagagg tatcagcatg agagatttga ttttccttaa
    13381 agctcaaaat aggatagttg agcctaaaga agtggaagtg ctgacttgag aaataatatt
    13441 gctgaatgtc attgtatgaa ctataatgaa aagagaggtg ataagcaatg gaaatgatgg
    13501 accaagtcag gaaattttga tttttacaaa acaaattcgt cattggattc ttagtgatca
    13561 agttatttca gggaaaagaa aacttttctt ccgggaagat actccaaaag agattttaga
    13621 tttgtacgaa aacattaaat ctaaacttga ttttgcttac caataagttt attctaataa
    13681 tgggttgaaa aaatatgaaa aatagaataa ttgatgtttt tgaagtagta aatcgcatcc
    13741 ttgtaataac tgttgaaaat cctgatttcg aagacttgag agttaatcat actcaatgaa
    13801 aatcaaagag caaactagga aactagccgc aggctgtact tgagtacggt aaggcgacgt
    13861 tgacgtggtt tgaatttgat tttcgaagag tatcagtttg taaaaattgg agataaaaaa
    13921 tatagagtac gcagtgttcc tatgattcat tcaactccgc ctcaatctgt cttagatcga
    13981 gatactttta caattgacta tacagatgat gaattgctcg ataaagaagc agtttttact
    14041 actcattaga aaaataggtc tgaataaatt ggcttccctt agaaccacat ctaggggctt
    14101 ttatgtataa tagaataata agtatcactc ctttacaata cgtgtaacac gtgttataat
    14161 ggtgttgtca ggaggtaaaa gcgctatgcc tatgacacaa aaagagatgg ttaaactcct
    14221 tacggcccat ggttggataa agactagagg cggtaaaggc tcccatatta aaatggagaa
    14281 gcaaggggaa agacttatca caatccctca tggtgagctg aataagtaca ctgaaagagg
    14341 gataagaaag caagctgggt tgtaaaattc agcccctgtt ttttgatatg gaggtagtga
    14401 aatgttagtt acgtatccag ctttatttta ttatgacgac acagacggaa cagaagcgac
    14461 ttattttgtc catttcccag attttgaata ctcagctaca caaggagagg ggatttctga
    14521 ggctttggct atggggtcgg agtggctagg gataactgtt gcagatttga tagagagtga
    14581 tggagagtta cctcagccat cagatatcaa tagcttgtct ttaattgata atgatccttt
    14641 taaagatgat gaagatttcg tgtcaaccta tgaccttgat aaatctttta tttctatggt
    14701 atctgttgat gtatcagaat acctaggaag tcaggaaccc ataaaaaaga ctttgaccat
    14761 accaaaatgg gcagataagt tgggacgaga aatgggactt aacttttctc agactttgac
    14821 agacgctatt gcagataaga aagttcaagc ctaagattaa gcgtggtatc gtggtaatag
    14881 tcaataaaaa agcacgtcca cttgtgctag ttactcgcct attgatttta tagatttatt
    14941 agccctttcg agggcttttt atattgattt ttatgagaaa tgaagaaatc agacttttaa
    15001 gaaaatcact gataccaagg gtttaaatga ggtaatatgg tataattagg acataaaata
    15061 attttgtggt aagatggtag tatctatttt agcatatttc cgagcaatcg gggcgattaa
    15121 agagtcgcat agaaagagga caaaatggca acatacggat ttttagatgt tttagaggaa
    15181 gagttggaca agaactttcc ctttgacttt gagattagct gggacaaacg caaccatgcg
    15241 gtagaagtga gttttctatt ggaagcgcaa aatgctgcag gtgtggagat ggtggatgaa
    15301 gacggagagg tttcatcaga tgacattctt tttgaggaag cggtcctttt ctacaatcct
    15361 gccaagtcaa cagtcaatga ggaagactat ttgactgtta ttccttacct gcctaaaaaa
    15421 ggattttccc gtgaattttt agcttatttt gcgcttttcc ttaaagatac tgctgaggtt
    15481 gggctagatg tcctcatgga ctttttggaa gacccagaag cagaggaatt tatcatggaa
    15541 tggaaccaag aagtctttga agaaggaaaa gttggcttgg aagagggaga attttatcct
    15601 tatccaaggt attagaaaag attctaagtg gacattttta aataatgaat tcaaggagaa
    15661 gggggagatt atgctagaaa aagtcaaaca gtttttcagg agcaggtcag ctaaaactga
    15721 gccgtcagtt gatattcttc cccgcaatcg ctttgaggat ctagatttcg agagagtatt
    15781 gaagtcagga gctcgtcgcc ttgttaatga ggaaggacgc tatgctgagg atgggaaaat
    15841 cacagaactt gaatttcctg aagattttgc ggaatttgaa tttctagttg gttttaagac
    15901 ggaggaagaa gagcagtttc agcaactatt agctcgttta aatagtattg acaatgctat
    15961 tcagtcctat ttggaaagtg agatgcaaca acccatccct cagtatgcca aggatctcgg
    16021 ctatactcag aagaggtggg agaaaacctt ttacttccat ccttggatat taagtggtga
    16081 ggaaaacccg cctaatcttc gctatgttgc agattatgta aatgatgagt ttacggttta
    16141 ttttgctaaa aaacatggca gatggcaagc atactgggat gcagagtgcc aaaaagtaat
    16201 cgaagaaagc tagctcgtat tttcctagag agtaattgtt atcatagaaa agagtaaata
    16261 tcatggaatt attgaatagc agaatggatt tccaaggttg caagattgcc ctcttttgtg
    16321 gggataagct actgacgatt ttgcgtgatg acaaggacga tatcccttgt cccaacatgt
    16381 gggagttgcc aggtggggga aagagtgtca gggaaaatct gatatagttt tgcattaaaa
    16441 gaatatcctt tcaaggttat tcttttttaa ttttgtccca aaataattga ctttgtccca
    16501 aaaatatagt attatttgta taaggaggaa tgaatcatga aaaaatcaga tgttcttgat
    16561 ttaataaagt atcattatga gggcagagag acagaattta gaaatcaatc catagcaatt
    16621 gctcggaact tcaataaaca tggtgataca caaatagcac aatatattat ggggttaatg
    16681 tctcaaagtg atagattcat gccacaaata gaaaatccta gtgagtattt gactcctgct
    16741 aaactagata ttggtcctct cccattgcct ctttcaatta tgaatgattt aaaaggaata
    16801 ataaacgctg tcaatcatca tattggaata aataaatttt tatttgtggg atctccaggt
    16861 actggaaaaa ctgaaagtgt aaagcaggtg gctagactta ttggcaagga attacttgta
    16921 gtagatttca gtcacttagt agatagtaag ctagggcaaa cagtcaaaaa cttagcaact
    16981 ctttttaatg aaatcaataa tcttcctttc aagcaaaatt atatcatcct atttgatgaa
    17041 attgattcca tagtgttgga tagggttaat cagaatgatt taagagaaat gggacgagtg
    17101 acttctgcct ttttaaagga gttggatagg ctgtcaccag aaattgtatt aattgcaaca
    17161 acaaatcttt ttgaaaatct tgataaagca gttacgagaa gattcgatgc cataattgac
    17221 tttgaccgtt atactgatga agataaagta gaagtagcta ctattatttt aaatgagtta
    17281 ttaaagcaat ttaagaatgt agctagagat ttaaaattat ttaaaaaaat tatcaatagt
    17341 gccaatgtaa taccgaatcc tggtgatttg agaaactcaa taagaacgtc attggcattt
    17401 agtgacccat cagatccgca tgattaccaa aaacgcctgc taagaagttt gcataatggt
    17461 agaaatttat ctatttctaa attatcgaag ctaggtttta ctgttagaga aattgagatt
    17521 ttgacaggta tttctaagag tagtgtatca cgagagttaa gcgaggatta aaatgaatac
    17581 attattgaca ttacgaggta aaagttttac accaaagtca gcaaagggga ggggaccgat
    17641 aacgattccc gcagattcta ttgttacgct aaaccattta aatgaacttt atacatccct
    17701 tgaacgagta aaagaatatt ggtctaataa cacaatcatt gatggagtac ttattagtgt
    17761 gtattataat cgtgtcctag ctaagagcaa tcgtatcgat ggttttttta atgtgggtgg
    17821 cggaaatgca attccaaatg aaacgattgt gggtgcaaaa tttagtaatg ataagagtag
    17881 gcatattatt acacactaca tttcaaagga agtgttagat aagacaattg agcatactaa
    17941 aaaagttata acaatattca aagattattt tgctagtgct cccatgacga gtatggtgtt
    18001 ctccgactct tcaaaattta atcaaattga ttattctaag tatggtctgt cgaaatcaaa
    18061 attcaaacaa tacttaagag acgcttgctt tgtcaaagga tttggtattg aacaggcaga
    18121 tatgtctact atacgtaatt ctattgtaac aatctacgat gtaaaaacta atctcttaac
    18181 attacttaaa caacttgata ttgatgtttc agaagctaac atcatggacc agacaactgt
    18241 tttacttgac gaaaaaaata ttgagttact actgctaaaa gcaccttatc tagtatcaat
    18301 gatagtagaa gatttttcta gcctgtcacc agagaatttt tataatgatg ggaacacttt
    18361 ttataataat ctcccttttc caactaatga acctattatt ggtgtcatcg atacgttgtt
    18421 tgatgataga gtttatttca atgagtgggt agagtatcat gatttaattt caccagatat
    18481 tagcaaagga agtcaagact ataagcacgg tacagcagtt tcctcggtaa tagtagatgg
    18541 agctagtttg aatccaaaac tagatgacgg atgtggaaga tttagagtca gacattttgg
    18601 gatatcttta cagagtggtt tcaattcctt cacaattatc aaacagatta gagaaattgt
    18661 gtctcaaaat cctgatatta aggtttggaa cctttcgctt ggatcaaatg atgaaattag
    18721 ggaaaacttt atttctgtcg agggttcgtt gttagacgag attcaatttg ataacgatgt
    18781 aatttttatt attgcaggca ctaatgggat tgcccctgat ggacaacgaa aaaagattgg
    18841 agcaccagca gattcactca attcaattat tgtaaattct gttgatttta gcaatcaagt
    18901 cgtttcttat tcacgcgaag gagttgtcct gtctttcttt atcaaacctg atgtttcata
    18961 ctatggcggg gggaacggag acttcataaa tgtttgtgaa ccactagggc tggctcgagt
    19021 agctgggacc agttttgcgg ctccatttat tgctagaaaa atggcttacc tcattcatat
    19081 tatgggatta agtcgtgaag aagcaaaggc tttattaatt gattcagcga taccatggaa
    19141 tgataaaaaa acattcgcag acatttcttt acttggatat ggggttgtgc caatcaaaat
    19201 agaagatatt ttgtctacac ctgatgatga aattaaattt atagtctcag atgtttctag
    19261 agcatatgaa acttataatt atgatttccc agttccaatt tctaaagaac actatccata
    19321 tgtagcaaag gccactatgt gctattttcc aaagtgttct agaaatcaag gagttgacta
    19381 tactaatacg gaaatgcaac ttagtttggg agttttagat aagaaaggca ttaaaacaat
    19441 taataacgac aatcaatatt ctgaaaatgc accaggatat gtgagagaaa agtcggcacg
    19501 aaatattttt aggaaatggg ataatgtcaa acatttagga gaaaaatttt cttctcgtaa
    19561 aaaagctaag ccgattctga atccttctaa tcctcaatgg ggaatgagtg taaaaacaat
    19621 tgaacggtta agaaatgatg atggttatgg tatccgtttt ggagtagttg ttactctaaa
    19681 ggagttgaat ggtgtcaata gaatcgaaga ttttattcaa caagccgaat tacgcggttg
    19741 gctagttaat agattgcaag tagaagctca agtagacctc tttaatagtt taaatgaaga
    19801 aattgaattt gaatagtgga tattttatcc ttattctaga tcttaggaac acaagagggc
    19861 aaagatatga atattactta tatagttgga aatggtttgg atttgcaata tggtttgaaa
    19921 acaagatata aagatttcta tgaatttcaa aataggactt acataagtag gaaagagaac
    19981 gaggaagaat attcaaatct catttatgag tctctatttt ctgatacagt aaatgattat
    20041 gaaaattggt cagattttga attgtcaatt ggtaaattaa caaaagataa cgacctcatc
    20101 tcctcaagta tagaaataaa ggagaaattt atagatgatt ttagtgaaat agttgatgat
    20161 ttaagagaat atctacgcat acaacaagaa aaaaatcttg agaaaggtaa tgcaattgac
    20221 tttataagca ctctagataa tatgaggacc tctctccctg taattaatca acctgctatc
    20281 gataaaaaat ataatgaaaa tctatatcaa cacgatatcg tgaatatatt aactcttaat
    20341 tacacaaatg taatcgataa attatataat gagtcagcaa aatcatttag caatcaatta
    20401 cgaactaata attataaatt tcacattgcg cctccaattc atgcacatgg aacggtagat
    20461 atttgcacag ttttaggagt tagtgacgag acacagattt caaatagttt tgatgaagaa
    20521 caaaaagaat ccttaataaa aaatttagtt ttgaagaact atagagaaaa tatggatgtt
    20581 aaaaatagcg atattataaa aaattctgac atcataattc tttatggggt ttctttggga
    20641 gagactgatg ggtatatctg gaatcagatt gctgaacaat caatcagaag ttctgttcct
    20701 gtcataattt accattatgt acctcatttt gatgcaggaa accccactag agtaaaacgc
    20761 ttatatagaa atgtagaaga caaattcata caaaatagtg gaattgattt agagttagag
    20821 aagaaattaa gagataacct tattgttgtt attggaaaga ctatttttaa tctgatggaa
    20881 aggtaagcaa aatacataat ggaaacatgg caagagttaa aagttacagt gaagcgtgag
    20941 ggagaggagt tggtttccaa tctcttgatt gagctgggag cgcaaggagt cgcaatcgaa
    21001 gacagtatgg actatgtggg aaatgttgac cgctttggcg agattttccc agaggtggag
    21061 cagcaagaag aaatcgtagt gacagcctac taccctgaca cggtggatgt gacagtggtt
    21121 gaggcggatt tgcaggctcg tctagcagaa ttgacagatt ttatggattt gggagagtta
    21181 aaaataggta cgactgcctt ggctgaggaa gactgggcag acaactggaa gaaatactat
    21241 gaacctgctc gcatcactca tgatttgacc atcgttccct cttggacaga ctatgaggcg
    21301 actgcgggag aaaaaattat caagctggat cctggcatgg cttttggtac gggaacccac
    21361 ccaactacca agatgagcat ttttgccttg gaacaggttc ttcgtggtgg cgaaacggtg
    21421 ctagatgtgg gaactggttc aggggttctc tctattgcca gctcgcttct gggggctaaa
    21481 gaaattttcg cctatgacct ggatgatgtg gcagttcgtg tggctcagga aaatattgag
    21541 ctcaaccctg gaatggaaaa tatccatgta gtggcaggcg atttgcttaa aggcgtggag
    21601 attgaagcag atgtcatcgt ggcaaacatc ttggcggata tcctcattca tctgacagag
    21661 gatgcttatc gcttggttaa ggatgaaggt tacctgatca tgagtggcat tatcaaggat
    21721 aagtgggaca tggtgcgcga gttggctgaa tcagctggat ttttcctcga aactcacatg
    21781 gttcaagggg aatggaatgc ctgtgtcttt aagaaaacca aggatatctc tggtgtgatt
    21841 ggaggctagc atgcagcagt attttgtaaa aggcagtgct atctctcctg tcactatcga
    21901 gaacaaggaa accagtaagc atatgtttca ggttatgcgc ttgaaagaag aggatgaggt
    21961 taccttagtc tttgatgatg gcatcaagcg cttggcgcgc gtgctggata tggaaaatcg
    22021 tcagtttgag ttggtccaag aattaaatga caatgtggaa ctaccagtcc aagtgaccat
    22081 cgcatctgga tttcccaagg gagacaagct ggagttcatc gctcaaaaag taaccgaact
    22141 gggtgctagc caaatctggg cctttcctgc agactggtca gttgccaagt gggatggcaa
    22201 gaaattgggt aaaaaagttg aaaaactaga aaaaattgcc cttggagcag ccgagcaaag
    22261 caagcgtaat attgtaccaa gtattaaact tttcgagaaa aaagcagatt ttctagctca
    22321 gctggaccag tttgactcta tcatagtagc ctatgaagaa tcagctaaag aaggagaagc
    22381 cgctgcgctt ctgcaagcag tcactggtct tgaaacagga gccaaactgc tctttatctt
    22441 tggtccagaa ggcggtctct cacctgcaga aatcgaaagt tttgaagcta agggagccgt
    22501 tttggcaggc ctaggtcctc gtattttgcg agcagaaaca gcaccgcttt acgctttatc
    22561 agcccttagt gttttagtag aattagagaa ataagaggaa gaaaatggaa caaaaacacc
    22621 gttcagaatt tccagagaag gaactctggg acttaacagc cctataccaa gaccgtgagg
    22681 atttcttgcg tgcaatcgag aaagctcgcg aagacatcaa ccagtttagc cgtgattaca
    22741 agggcaatct tcacactttt gaggatttcg agaaggcctt tgcggaattg gaacagatct
    22801 acattcagat gagccatatt ggcaactatg cttttatgcc tcagacgacg gactatagca
    22861 atgacgaatt tgccaatatt gcccaagctg ggatggaatt tgaaacagct gccagcgtag
    22921 ccttgacctt ctttgacgat gccttggtgg cagcagacga ggaagtcttg gaccgtttgg
    22981 gtaaattgcc acatttaaca gctgccattc gtcaggctaa aatcaaaaaa gcccactact
    23041 taggggcaga tgtggagaag gccttgacaa atctcggtga agttttctat agtccgcagg
    23101 acatttatac taagatgcga gctggggatt ttgaaatggc tgactttgaa gcccatggca
    23161 agacctataa aaacagcttt gtcacctatg agaatttcta ccaaaatcac gaggatgctg
    23221 aggttcgtga gaaatccttc cgttccttct cagagggact tcgtaagcac caaaatacgg
    23281 ctgcagcagc ctatctggct caggtcaagt ctgaaaaact cttggctgat atgaagggat
    23341 acgactctgt ctttgactat cttctagctg aacaagaagt ggaccgtgtc atgtttgacc
    23401 gccagattga cctcatcatg aaggactttg caccagtcgc tcagagatac ctcaagcatg
    23461 ttgccaaggt aaatggtctt gaaaagatga cctttgcaga ctggaaattg gacttggaca
    23521 gcgccctgaa tcctgaagtg actattgacg atgcctatga tttggtcatg aagtcggtag
    23581 aacctttggg gcaagaatat tgtcaggaag ttgctcgtta ccaagaagag cgctgggtgg
    23641 attttgctgc taacagtggc aaggattccg gtggttatgc ggcggaccca tatcgcgtac
    23701 acccttatgt actcatgagc tggacaggcc gtttgagcga tgtctatacc ttgattcatg
    23761 aaatcgggca ttctggtcaa ttcatctttt cagacaatca ccaaagctat ttcaacgccc
    23821 acatgtcgac ctattatgtt gaagcaccgt caaccttcaa tgaattgcta ctcagtgatt
    23881 acttagagaa ccagtctaat gacccacgtc aaaaacgctt cgctctggct catcgcttga
    23941 cagacaccta cttccataat ttcatcaccc acctcttgga agccgccttc cagcgtaagg
    24001 tgtatacatt gattgaagaa ggggagacct ttggagcaag caagctcaac agcattatga
    24061 aggaagtttt gacagatttt tggggcgatg ccattgaaat cgacgacgat gcagctttga
    24121 cttggatgcg ccaagctcac tactatatgg gcttgtatag ttacacttac tctgctggtc
    24181 ttgtcatctc gacagctggt taccttcatc ttaaaaactc agaaactgga gctgaagact
    24241 ggctcaatct cctcaaatca ggtggtagca agacaccact tgagtcagcc atgattatcg
    24301 gtgctgatat ttcaacagac aaaccactcc gtgataccat ccaattcttg tctgacacag
    24361 ttgaccagat tatcgcctac agtgctgagt tgggggagta aggggataga gaggttgtta
    24421 tagaatgggt atggacagtt atttgcttaa aagtccatgt ttaaatcccc cattcctttt
    24481 cgaggaattc tttgcccttc tctgtaatgg taagtgaacg tggcgtttgt gcagggatga
    24541 ccaattgttt ttcactgaaa aattctaaaa gagcattgcc gagagctccg ccgacatgat
    24601 ttttacgttc gctccaatcc aaacatttag ggcaaaattt ccgttttttc tttttcaatt
    24661 catccgtatc aatgtgtaat tttctttgga aataagactt cccagcttca gtgagttgga
    24721 agtctttttc tgatcggatt gaagattact ggactttcag taaacccagc tcgtagcttg
    24781 gcaccagctg tcttggtggg cggcgcagcc cttcaacaag tttggatttt catccttgca
    24841 ccaatcgctg gtggagttct tgcagccctt gttgcaaaaa atttccttgg aacagaagaa
    24901 taattgaaac tcaaaaagcc ttgctcctca tcttgaggaa cagggctttt tcgtatgata
    24961 ctcttcgaaa atctcttcaa accacgtcag cttcaccttg ccgtaggtat ggttactgac
    25021 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag taacctgcgg ctaacttcct
    25081 agtttgctct ttgattttca ttgagtatga ctttagcggt tgtcaatttt ctctggataa
    25141 aggtcgtgtt ggaagaggcg ttgttctgcc aagccctcat acttagttcc ttgcttaccg
    25201 tagttgtagt aggggttgat tgaaatgcca ccgcgcggag tgaatttccc ccagacttct
    25261 aaatagcgag ggtctagcaa gttgaccaag tctttcccga tggtgttgat acagttttcg
    25321 tggaaatctc cgtggtttcg gtagctaaat agatatagtt tgagggattt tgactcgaca
    25381 cagagtttgt caggaatgta ggaaatatga atcgtcgcaa agtctggctg agcagtgatt
    25441 tgtcccagca gagacatatc gaggatatgg tgacgaatgc cctgttcctt agcgatttct
    25501 ctattaattt gaatttcgag gtgatgacgt tggccgtagg caaaggtgac agcttcgact
    25561 gtttcatagt gttgcatggc ccagaaaagg caggttgttg aatcttgacc accactaaag
    25621 acgaccaagg ctgattgacg tttcatagta ctccttccaa aatgggaaat gttcagagca
    25681 tgcaaaaagc tcccattagg gagctaaaaa ataccaaatc gagttttttt agcgatggca
    25741 tatcccaaac atcgtaatat tctacttata tagtaaaa
//
LOCUS       DBERAE010000029        25692 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.29, whole genome shotgun sequence.
ACCESSION   DBERAE010000029 DBERAE010000000
VERSION     DBERAE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.29"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            144..395
                     /locus_tag="ACL70N_001412"
     CDS             144..395
                     /locus_tag="ACL70N_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590197.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            624..926
                     /locus_tag="ACL70N_001413"
     CDS             624..926
                     /locus_tag="ACL70N_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590198.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYEEDFLI"
     gene            923..2269
                     /locus_tag="ACL70N_001414"
     CDS             923..2269
                     /locus_tag="ACL70N_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HGS0590199.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDEHWLYNLPS
                     NITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTGLNGY
                     SQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGEFVKD
                     STFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADKLSEYNMVSGSYDWFLTLIDYMEIINSKYNLSYRDLSFNNILIDNRNNIYIID
                     FEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYWSQNLDDFNVF
                     SKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELKKDFIEVLK"
     gene            2283..3200
                     /locus_tag="ACL70N_001415"
     CDS             2283..3200
                     /locus_tag="ACL70N_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0590200.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            3197..3997
                     /locus_tag="ACL70N_001416"
     CDS             3197..3997
                     /locus_tag="ACL70N_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590201.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            4155..4628
                     /gene="tnpA"
                     /locus_tag="ACL70N_001417"
     CDS             4155..4628
                     /gene="tnpA"
                     /locus_tag="ACL70N_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HGS0590202.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            4885..5106
                     /locus_tag="ACL70N_001418"
     CDS             4885..5106
                     /locus_tag="ACL70N_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0590203.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERSEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            5408..5641
                     /locus_tag="ACL70N_001419"
     CDS             5408..5641
                     /locus_tag="ACL70N_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS0590204.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            5717..7225
                     /locus_tag="ACL70N_001420"
     CDS             5717..7225
                     /locus_tag="ACL70N_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0590205.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKRESRKRLDAKFLAIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRTIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFKHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            7306..8157
                     /gene="ylqF"
                     /locus_tag="ACL70N_001421"
     CDS             7306..8157
                     /gene="ylqF"
                     /locus_tag="ACL70N_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGS0590206.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEKAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8144..8923
                     /locus_tag="ACL70N_001422"
     CDS             8144..8923
                     /locus_tag="ACL70N_001422"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGS0590207.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            8939..10489
                     /locus_tag="ACL70N_001423"
     CDS             8939..10489
                     /locus_tag="ACL70N_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGS0590208.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            11137..12207
                     /gene="xerS"
                     /locus_tag="ACL70N_001424"
     CDS             11137..12207
                     /gene="xerS"
                     /locus_tag="ACL70N_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGS0590209.1"
                     /translation="MKREILLERINKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAINLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12280..13269)
                     /locus_tag="ACL70N_001425"
     CDS             complement(12280..13269)
                     /locus_tag="ACL70N_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGS0590210.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13333..15036)
                     /gene="lpdA"
                     /locus_tag="ACL70N_001426"
     CDS             complement(13333..15036)
                     /gene="lpdA"
                     /locus_tag="ACL70N_001426"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGS0590211.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELESEEDGYLIAILKGEGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVITDKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            complement(15082..16125)
                     /locus_tag="ACL70N_001427"
     CDS             complement(15082..16125)
                     /locus_tag="ACL70N_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGS0590212.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            complement(16343..17335)
                     /locus_tag="ACL70N_001428"
     CDS             complement(16343..17335)
                     /locus_tag="ACL70N_001428"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGS0590213.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            complement(17351..18319)
                     /locus_tag="ACL70N_001429"
     CDS             complement(17351..18319)
                     /locus_tag="ACL70N_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGS0590214.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            complement(18473..19834)
                     /gene="pdrM"
                     /locus_tag="ACL70N_001430"
     CDS             complement(18473..19834)
                     /gene="pdrM"
                     /locus_tag="ACL70N_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGS0590215.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            complement(19845..20105)
                     /locus_tag="ACL70N_001431"
     CDS             complement(19845..20105)
                     /locus_tag="ACL70N_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590216.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            complement(20119..21387)
                     /locus_tag="ACL70N_001432"
     CDS             complement(20119..21387)
                     /locus_tag="ACL70N_001432"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGS0590217.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            complement(21400..21864)
                     /locus_tag="ACL70N_001433"
     CDS             complement(21400..21864)
                     /locus_tag="ACL70N_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGS0590218.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            complement(21874..22527)
                     /locus_tag="ACL70N_001434"
     CDS             complement(21874..22527)
                     /locus_tag="ACL70N_001434"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGS0590219.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            complement(22665..23312)
                     /locus_tag="ACL70N_001435"
     CDS             complement(22665..23312)
                     /locus_tag="ACL70N_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590220.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSDDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            complement(23326..24039)
                     /locus_tag="ACL70N_001436"
     CDS             complement(23326..24039)
                     /locus_tag="ACL70N_001436"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGS0590221.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(24498..24878)
                     /gene="dhaM"
                     /locus_tag="ACL70N_001437"
     CDS             complement(24498..24878)
                     /gene="dhaM"
                     /locus_tag="ACL70N_001437"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGS0590222.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(24878..24952)
                     /locus_tag="ACL70N_001438"
                     /pseudo
     CDS             complement(24878..24952)
                     /locus_tag="ACL70N_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            complement(25300..>25692)
                     /locus_tag="ACL70N_001439"
     CDS             complement(25300..>25692)
                     /locus_tag="ACL70N_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGS0590223.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT         8047 a         4872 c         4757 g         8016 t
ORIGIN      
        1 atctaaatta agctttaaaa aattattttt agcaatttga ttttgaaagt gtcatgcagc
       61 aatatgaaag cgtagaatag aggtgtttcc aatgtacaag taagttttga ttccaaataa
      121 agtaatagaa aaggagctat ataatgagta gtcaaatgaa agctttcttg aatgaacttc
      181 aaggaaatat ggaagttgtt ggagaatttt ttgataatcc tgaaaaggta attagaaaat
      241 ttggaattgt cggaagagag aaggaagcat tgctaatccg tgacttaaat gatatggatg
      301 attatgctct ttcaattcaa aatagcgttg catcgccttc tggggcacat agtagcactt
      361 gccattttgt tagacaagat ttacaatccg cataattgtt aatatataaa acataaaatt
      421 tcaattttca attagggata atagaattcc ttactatgat atagaaagtg aattaattag
      481 gaaatcttag tcagaggttt ctgattaatt cattttttat atattaagag tgatgtgaaa
      541 tgttcaaatt gtgagactac tctcggattg ttgtatagaa atttaaaatt ttattgtgag
      601 ctttttaagg aagagtggcc gatatgaaaa ataaatacga tgttaaaaga attattccgg
      661 atgaattatc agaatcacta gatatttttc taaaaaatta ttctgaaact ggattgtcag
      721 attataatac ttatctcttt tatggtttta tcttgaagtc ctataaattg cctcgagaaa
      781 atagatatag cataaaatta ttggtgaagg aattacaaaa tagaggactg aaagttacat
      841 tgattatcaa catttattat cacgctttaa attgtttggc tttaaatgat ggtctaaaaa
      901 tttatgaaga agatttctta atatgaatta cgaaaagtat ttaaactatt tggactatga
      961 aactgaaata gaagacgcat accataattt attattagaa tataaaatta gtgataattt
     1021 tagtgatgaa cattggttat ataatttgcc gtctaatatc acccaatcta agggatttaa
     1081 aatacacctg agcgcttcaa tattaaatgc taatttggtt gctaaaaaat tctttgattt
     1141 tatattttct agagagaaga agataaattt caaaattttg gttagcatta aagaactttc
     1201 tttgcaaaat acagggctta atggttattc acaagtcggg aaattcatta caatttatcc
     1261 aaaagataat aaagaatttc aacgtttgtt acacaaatta gaaatattgt ataaaggtgt
     1321 aaagggtgta aacataccat cagatttcag atttcaactt agcgaggttg tatattacag
     1381 atatggggag ttcgtaaaag atagcacttt caaggataaa agagataaga aaatcccttc
     1441 aaatgtgaat gttccaataa gggattacta tattccaaga tataacacta ttcctgatca
     1501 atatattatt ttggaagtga tttctaaaaa tgccaaaggt ggagtttata aagtatttaa
     1561 tactcaaaag cgagtttatt ctttattaaa agaagctagt gatttatcgt tggttgattt
     1621 tacaaataga gattctgtga atcgtttaat aaatgaaaga gaaatattag tagaattgga
     1681 aaaggaggaa tttactccaa aagtttttaa cgatttttac ataaagaatt cgtattttgt
     1741 ggaatttgag tttattattg cagataaatt aagcgagtat aatatggtta gtggctcgta
     1801 tgattggttt ttaacattaa ttgattatat ggagataata aactccaaat ataatctttc
     1861 ctatagagat ttatcattta ataatatact tattgataat agaaataata tttatattat
     1921 agactttgag catgccctaa ggaaagaaac tcaaattgaa gaaaaaaagt tgcctctatt
     1981 tggaactcca gggttttatg aaaccaactt aaatttattg aataatcaac cagaggatat
     2041 tatgggattg gttttgttat tatattggag tcagaattta gatgatttta acgtcttttc
     2101 aaaaatgagt tttttagaag cgatggagta tgcaatgaat tttaattcgc gtcgcttaga
     2161 cacacttgat aaatcagatt ggctttatga tatttataaa aaagcgttca attataaata
     2221 tgatactttt tctgaattaa aaaaagattt tatagaggta ttaaaataaa ggtaggggtg
     2281 ttatgaattg tttcttgaaa atgaataatg taagtgttcg ttatgatgac gtaatagctt
     2341 taaaagatat aactttacaa ataaataagg gagatttcat tggcttatta ggttcaaatg
     2401 gtgcaggtaa atctacgtta attaattcta ttgtaggttt tcaagagatt tatttaggag
     2461 aaatagagta ttgtgataaa gatttgatag ttagttctca accttttgct catttaggct
     2521 ttactcctca aaccacagta attgattttt atactactgt gaaggacaat gtaatattgg
     2581 ggctgaacct tgctggaaag tttgggaaaa atgctgagaa gttgtgtcaa atagccttag
     2641 aaattgttgg gttagctgat aaaaaaaata atttggtaga aacattgtca ggtggacaac
     2701 tgcaacgcgt ccagattgct agagcaatag ctcataatcc agatttttat attttagatg
     2761 aacctaccgt tggtttagat actgaatctg ccgaaaaatt tttaatgtat ttaaaagata
     2821 agagtttgga aggaaaaact attatcatat cttcacatga cataaatcta ctcgaaaagt
     2881 tttgtaaaaa aatacttttt ttacaaaatg gctccatatc attttttggt gatatgcgtg
     2941 actttgtaga taattcaact atcaaattaa atttttcaat gcagaataga atttctagat
     3001 atcaaattga atttttagaa aattttagat ttaaagttca catcgaagat aatgatagtt
     3061 ttacaataga agtccctata gaagaaaata tcttagatgt tatcaatgag gtaggaaaag
     3121 catgtgaaat taaaaacttt tcaacaagta aattaacctt acaagaaagt tatttgcaaa
     3181 gaataggagg agaaaaatga aggctgatca attaaggcac aaatcggact taggtttaag
     3241 aggtctagcg attattgcta aaaatgagat tattgctttt tttagaagta aaggtttaat
     3301 tatttctcag tttctacaac caatcttata tgttgttttt ataataatag gattaaattc
     3361 ttcgataaag aacattcagt ttaatgatat aaaaacctct tatgcagaat atacaatcat
     3421 tggtgttata gctttattga taatcgggca gatgactcaa gttatttata gggtgacaat
     3481 agataaaaaa tatgggctac ttgctcttaa gttatgcagt ggagttcgtc ctttatatta
     3541 tattttaggg atgagtatct attctatatt agggttgata gttcaagaaa ttattatata
     3601 tataattacg ttagcgtttg agataaatat cgcaatggat agattttttt atacagtttt
     3661 gttatctatt gttgttttat tattttggga ctcccttgca attttactta caatgtttat
     3721 caatgattac agaagacgtg atattgtaat acgttttgta ctaacaccgc ttggttttac
     3781 agctcctgtt ttctacttaa tagattctgc tcctagtatt gtgagatgga ttggtcagtt
     3841 aaatccctta acttatcaat taactatttt gagaaacttt tattttaaaa attcaacaac
     3901 tttggaatta gttttcttat tgttaacatc attacttgtc cttatatctg tatcttttat
     3961 tataccaaag ataaaattga tactgataga aagataaaag ttgggtcatc caactttttt
     4021 gttgtctccc gaaaaccact agctatgcta gtggttccat agagctttta gcgtggtaac
     4081 aaaaagaacc tcctaaaatg ataagataga agtggtttct ccgccactac aacatatcat
     4141 acaggaggta cctcatgaga gaggataatc aaagtttatc acataccaca tggaattgta
     4201 aatatcatat tgtttttgca cccaaatatc gtcgtcaaat catttatggc agatacaaag
     4261 ctagtatcgg aagaatcata cgtgacttat gtgagcgtaa gggtgtaata atccatgaag
     4321 cgaatgcttg ttcagaccat attcacatgc ttatcagtat tcctccgaaa cttagtgttt
     4381 cgtcctttat gggctattta aagggcaaga gcagtttgat gatttttgat aagcatgcga
     4441 atttaaaata caaatatggc aatcgcaagt tttggtgtag aggctattat gtagatacgg
     4501 taggccgtaa tcagaaagtg atagctgaat atattcagaa tcaattacaa gaagacagag
     4561 tagcagacca gctcacgtta ttcgagtcag tagatccgtt tactggcgaa ataaataaga
     4621 ggaagtaact aaggtgcttt agcacctgct cgggaaagtg gtgcgcgagg aagctatttc
     4681 ggtgggcctt tggccctggc cggtagaagc ggcttatagc cgcagaacaa accaccagtt
     4741 cacactggtg gttttgattt aaaaaacttg atacataaaa ataaaagtct atataaagga
     4801 tggtaaaatt cctgttgtcc gatttggaca atatcctaaa tagttacaat atatggtcta
     4861 tactttttct taggagaaag ctagatgtac agacgtttga gagatttgag ggaggatcat
     4921 gatctgaccc aaaagcaaat agctacaata ctttcgttta caaattcagc ttatgccaaa
     4981 attgaacgga gtgagcatgc gttgacggct gatgtattgg ttaaactctc agatttctat
     5041 gacgtcagta cagactattt attgggatta actgattttc ctgataaaat tcgctttaga
     5101 aaataatctc ctcaatttca tagagtttga aaatgagtga gattttttat ttgccctttg
     5161 acaactgaat agcctaaaat ggtactttcc tcatttgtgg agcagttttg cttgattcgc
     5221 caagatagga gcggggacaa tcaccaataa aatagagcga tactctatct gccatgatgc
     5281 aaatgatata caatgatact tctgaacgtt caggctgccg tcgtaaaaga gcagtaagtg
     5341 agattcttat gatgacccca tcagtcatgc catggaggga gaagaaatta ttcgaaagga
     5401 tgataatatg gagataaaat acgtatctgt tgaaaattcg gtagctgagt gggcggataa
     5461 gaaaagcata ctgaaacgat gggaaggttt gaatctctac actcttaaca gatggatcaa
     5521 agaaatgaga gaaaataaga gattttcttt atacgtcatc aatcctacac ataagctggt
     5581 gtttataaat cttgagggat tcgaatgctt tttgagatgg aaacaaaagc ggacaaaata
     5641 aggaagtcat ggtataatat agagtagtta tttattctat acaacaatga tttatttctt
     5701 ttcgaggaat taaattatgt attatgtaac taaaacaaat tcaaaaggac aacccttgta
     5761 tcaagtggtt gaaaaatata aagatccact tactgataag tggagaacag taactgtcag
     5821 ctatactaga aatactagta gagcacgaaa gcaagctgaa agagaggtaa tggataaaat
     5881 agaaaaactg acctcttccc ttgaaagtca gtacaatcct gaaatgatta caacttttgg
     5941 agagttaaaa gagagttggt ttcaaacttg gtgcgtatct gtcaagcccc agacaataaa
     6001 aagggaagag ttggtgatag aacggcttgg taaaattatc ggtgatgaat ttttactcga
     6061 tcgaattaca ccactactga tgaaaaattg tcttaataaa tatctggata aatacgacgc
     6121 ttcaccttca acaatgacac atataaaaag tacgtgtaac aagatattta atcacggtgt
     6181 gctatacaat gtcattaagt actctccaat gaccgctgtt aaaatagatg tgcctctgga
     6241 gaaaaagaga gaatcaagaa aaaggcttga tgctaaattt cttgcaattc atgaattgca
     6301 agcctttttt gatgttttag ggcagtgtag aaatgctagc tattatgacc ttgctattgt
     6361 attattactg acagggattc ggattggaga ggctgctttt ttaccatcag atgttgattt
     6421 tgataagggg attttacata ttgataaggc tctccaatat catgatttaa aagttgatga
     6481 attttatttt gatacgacta agaccgtcaa tgctgataga gaggtagccc tcccaatagc
     6541 agcgagtgaa gcaatccaga gaactataaa aagaaatcag gaatttgaag cctatatgga
     6601 acaaaatcct agtcctgctt tcaaaaagtg tgatagtgta tttcaaactg agtatggttc
     6661 tccgataact tctcactcat ttcgtcaagt tttgaagagg gttgaggaga agttgttaaa
     6721 aaattgtcag aaggattatg gttttaaatg ggtcaagcat gtgacccctc attctttcaa
     6781 acatatgcac attagttatc ttcaaagtaa tgaaatgcac atagctgtaa aggatattat
     6841 gactagagtt ggtcatgcga attttgaaac cacgatgggc tacacccata acatcagtcg
     6901 ttcacaagaa aatactgtaa ctgctttaaa tcaatttgta gaaaagcaca attttcactt
     6961 taaagaattg aagagttaca cctgtaaata ttcgagaatg attgaacaat tcattgaaac
     7021 ttgtgatgat aacaataaag tagagttaag tgttgatgaa tttaaagact tattacacct
     7081 tggttcacgt tactcaccca aacatattgt ttcaaattta ctgttaaaaa tcaaaaaaga
     7141 tattgtcaaa tatcacccac agtttgatat aaagattgtg aaattaagcg ggaatcaaat
     7201 caaaggtttt tccatttcgt ggtagttttg gtgttcgctt ggtgtttaga cgatagtaaa
     7261 ataaatgagg ggtgctaaac ccttgctacg aaaggaaaaa actcaatggc tactattcaa
     7321 tggtttcctg gtcacatgtc taaagctcgt cgacaggtgc aggagaattt aaaatttgtt
     7381 gattttgtga cgattttagt agatgcacgc ttgcctctat ctagtcaaaa tcctatgttg
     7441 accaagattg ttggtgataa accaaaactc ttgattttaa acaaggccga cttggctgat
     7501 ccagcaatga ccaaggaatg gcgtcagtat tttgaatcac aaggaatcca gacgctagct
     7561 atcaactcca aagagcaagt gactgtaaaa gttgtaacag atgcggccaa gaagctcatg
     7621 gctgataaga ttgctcgcca gaaagaacgt gggattcaga ttgaaacctt gcgtactatg
     7681 attatcggga ttccaaacgc tggtaaatca actctgatga atcgtttggc tggtaaaaag
     7741 attgctgttg ttggaaacaa gccaggggtc acaaaaggtc aacaatggct taaaaccaat
     7801 aaagacctgg aaatcttgga tacaccgggg attctctggc ctaagtttga ggatgaaact
     7861 gttgcactta agttggcatt gactggagct atcaaagacc agttgcttcc tatggatgag
     7921 gttaccattt ttggtatcaa ttatttcaaa gaacattatc cagaaaagct ggctgaacgc
     7981 ttcaaacaaa tgaaaattga agaaaaagcg cctgtgatta ttatggatat gacccgcgcc
     8041 ctcggtttcc gtgatgacta tgaccgtttt tacagtctct tcgtgaagga agtccgtgat
     8101 ggcaaactcg gtaactatac cttagataca ttggaagacc tcgatggcaa cgattaaaga
     8161 aatcaaagaa ttccttgtga cagtcaagga gttagaaagc cctatttttt tagagcttga
     8221 aaaggataat cgctcaggag ttcaaaagga aatcagcaag cgtaaaagag ccatccaagc
     8281 tgaattagat gaaaatttgc gcttggaatc catgctttct tatgaaaaag aactttataa
     8341 gcaaggattg accttaattg caggtattga tgaggttggt cgtggtcctc ttgctggtcc
     8401 tgtagtcgct gcggccgtta ttttacctaa aaattgtaag attaaaggtc tcaacgacag
     8461 caagaaaatt cctaaaaaga aacatctgga gattttccaa gtcgttcaag accaagcctt
     8521 gtcgattgga attggtatca tagataatca ggtcatcgac caagtcaata tctatgaagc
     8581 aaccaaacta gccatgcaag aagcaatctc ccagctcagc cctcaaccag agcacctttt
     8641 gattgatgcc atgaaactgg acttgcccat ttcacaaacc tccattatca aaggagatgc
     8701 caactccctc tctatcgcag cagcatctat agtagccaag gtaacacgtg atgaattgat
     8761 gaaggaatac gatcagcagt tccctggcta tgatttcgct actaatgcag gatatggcac
     8821 agctaaacat ctggaaggcc tcacaaaact aggagttacc ccaattcacc gaaccagctt
     8881 tgaacccgtt aaatcactgg ttttaggtaa aaaagaaagt taattgaaag gaaataccat
     8941 ggaggaacaa tcggaaatag tccgttctaa gaaagaattc gcctttgcat ccagcactat
     9001 actatcccaa gttggtcgag gaatcattgt cggcctcatc gttggaatta tcgtcggatc
     9061 ctttcgtttc ttaattgaaa agggcttcca cctgatacaa ggagtttatc aagatcaagg
     9121 gtacttagtg cgcaatcttt ttgtactggt tttgttttat atactcatct gttggctcag
     9181 tgccaaacta acacggtcag aaaaagatat taaaggctca ggaattcctc aagtcgaagc
     9241 cgaactgaaa ggcctcatgt ccctcaactg gtggggcatt ctttggaaaa aatatgtgct
     9301 aggtattctt gctattgcca gtggactcat gctgggtcga gagggaccca gcattcaact
     9361 tggagcagtt ggtggtaaag gaattgccaa gtggctcaaa tccagtccag tagaggaacg
     9421 ttccttgatt gctagtggag ctgcagcagg tttagccgca gcctttaatg ctcctattgc
     9481 agcacttctc tttgttgtag aagaagtcta tcaccatttt tcgcgctttt tctgggtctc
     9541 aactctagca gccagcatcg tagcaaactt tgtgtctcta ctcatgttcg gtttgacacc
     9601 agtattggat atgccagata acattcctcc catgacccta gaccagtatt ggatatatct
     9661 cgtcatggga attttccttg gattttcagg ttttctctat gagaaagctg tattaaacgt
     9721 tggaagagtt tatgacttga ttggtcaaaa aatccatttg gatagggctt attatcccat
     9781 cttggctttt atccttatca taccagtcgg aatcttctta cctcaaatca ttggtggcgg
     9841 aaatcagctt gtcctttctt taactgaaca aaattttagt ttccaagttt tattagctta
     9901 ctttttgatc cgctttattt ggagtatgat tagctatgga agtggactgc caggaggaat
     9961 tttcctcccc attttagctc ttggttcttt gcttggtgcc ttagttggtg ttatctgtgt
    10021 caatcttgga cttgtcagtc aagagcaatt ccctatattt gtcattctag gaatgagtgg
    10081 ctattttgga gccatatcaa aagctccctt aaccgctatg atcctcgtaa ctgagatggt
    10141 aggagatatt cgcaacctca tgccacttgg tcttgtcact cttgtttctt atattatcat
    10201 ggatttgctc aaaggtacgc cagtctatga agccatgctg gaaaaaatgc ttccagaaga
    10261 agtatctagc gaaggagaag ttacacttat cgaaatacca gtttctgata aaattgctgg
    10321 gaaacaagtt catgaactca acttaccaca caacgtcctc atcacaactc aagtccataa
    10381 tggcaagagc caaacagtta acggctcaac cagaatgtat ctgggtgata tgattcacct
    10441 ggttattcca aaaagtgaaa ttggaaaagt caaagatttg ttgttgtagt atgagcattt
    10501 acataattta tgttatgtaa atgctcagct tgatttattt agaaaaccga ttctcagaaa
    10561 tgagatcggt tattttttac tgatgaggaa ttttacatat aaataattga actttattaa
    10621 aaataagact ataattaatt aagttagaaa tgataaagca taaagctaga aaggagttta
    10681 ctgtatcaaa tctgtacagt aagattaaaa tcatgaaaaa gaaaacaata gtaattatag
    10741 tgaaatgaaa tagaaatagg ataaaacaaa caggacaatc aaatcaattt ctagcaatgt
    10801 tttagaagtc cagatgtact attctagttt caatctatta tacaatgtgt tttgtatctc
    10861 atagctcctt atatagctct tcagtctagt ttcaatctat tatacaatgt gttttgtatc
    10921 tcatagctcc ttatatagct cttcagttat gtagtattaa cagaagttta gtgggtgaga
    10981 ttttcattat tttccttatt ctgttttgtt tgtaggtcta agtcttttta tcactttgaa
    11041 aaactcctat aacatctttc tgaaaaacta taattttctt gaaaaatata caagtctatg
    11101 ctatactact agtatactta cttatggaga aaatacatga aacgtgagat tttactggaa
    11161 cgaatcaaca aactaaaaca actcatgccc tggtatgttc tggaatacta ccaatctaaa
    11221 ctggctgtgc cctacagttt tacaaccctg tacgaatacc ttaaggaata tgaccgattt
    11281 ttcagctggg ttttggagtc tggtatttca aacgctgata aaatatccga tattccttta
    11341 tcagttttgg aaaatatgtc taagaaagac atggaatcct ttatccttta tctacgtgaa
    11401 cgtcccttgc tgaatgctaa tacaacaaaa caaggtgttt cacagacaac tatcaatcga
    11461 accttatcag cactttctag tctttacaag tatctaaccg aggaggttga aaacgatcag
    11521 ggggaacctt atttctatcg taatgtaatg aaaaaagttt caaccaagaa aaagaaagaa
    11581 acccttgctg ccagagctga aaatatcaag caaaaactct ttctaggtga tgaaacagaa
    11641 ggttttctaa cttatatcga tcaagagcac ccacaacagc tttcaaatcg agctctctca
    11701 tcattcaaca aaaataaaga acgagattta gccattattg cccttctctt ggcatctggt
    11761 gttcgcttat ctgaagctat taatctagat ctaagagatc tcaatctaaa aatgatggtt
    11821 attgatgtta ctcgaaaagg tggcaaacgt gactcagtca atgtcgctgc ttttgctaaa
    11881 ccttatttag agaattatct ggccattcgg aatcaacgct ataaaacgga aaaaacagat
    11941 acagcccttt ttttaactct ctacagaggt gttcctaatc gtatcgatgc ttctagcgtt
    12001 gagaaaatgg ttgctaaata ctcagaggat tttaaagtac gtgtaacacc ccataaactg
    12061 cgccatacac tagcaactag gctctatgat gctactaaat cacaagtttt agtcagtcac
    12121 caactaggac atgccagcac acaagtcact gacctctata cccatattgt taatgatgaa
    12181 caaaagaatg ctctggatag tttatgattt tacgtatttt aaattatgta aataaatatc
    12241 aaaaaaagaa gttggttagt tggccaactt ctttttgatt tatccaacta ccgcttcagc
    12301 gatttcttca cggctaatac cagcgaagta gcgtgtgata tcaatggttt ttagcgcctt
    12361 aagaacatct tcgcgttcgt atttcacccc acgaaggaca tcttctactg cagcaacgtc
    12421 ttcaatacca aagaagtcac cataaatctt gatgtcttgg atttttgatt cagtaacgtt
    12481 agcaaagact tcaaccttac cactagtgaa tttggttcca cgacggacgt taaattcagg
    12541 tgatttacca tagttccagt cccaagttcc aaacttagta tccttgatgc gattgatttc
    12601 ggccaattct tcttctgaaa agacgtattc agtcatctct gggtactctt ttttcatgta
    12661 ttccaagagt aaatcacgga atttttcgac tgtgattttt tttggtaatt cattgataat
    12721 attggttaca cgggcacgga cggatttcac accttttgat tcaaatttat cttttgaaac
    12781 cttaagggca tttgcgagga ctgacaaatc aacgtcaaag agcaagcaac cgtggtgcat
    12841 gatacggccg ttgatatagg cttgggcatt gccacagaac ttcttaccat caatctcaag
    12901 gtcattacga cctgtgaact cagctttaac cccaagttga gccagggtat tgataaccgg
    12961 agttgagaag ctcttgaagt caaatgcctt attttcatct tctttggaga tgatcgtgta
    13021 gttgaggtta tttaaatcgt ggtaaacagc tccaccacca ctaatacggc gaactacctc
    13081 aataccattt tcgcgaacat aatcacggtt gatttcttcg atagtgttct ggtgacgacc
    13141 aacaatgata gatggcttgt taatccaaag taggaagatt tgatcctcat ccaaaaggtg
    13201 tttaaaggcg tattcttcca aggcaatatt aaaagcagtg tcatttgaat gattgataat
    13261 gtatttcatg atatcccttt actttatatg atagaaactg gaaataacct tccagtctaa
    13321 tctatctttg ttttattttt tcttaggtga atggatggcc attcctagaa catctgcaaa
    13381 cgcttcgtac atcacttcag agtaagttgg gtgcccgtgg atggtcttca gcatttcctc
    13441 aacagtgatt tccatttcga tgatgcttga tgcttcgttt attaattctg cggctgcagg
    13501 accaataatg tgtacaccaa ggatttctcc gtatttctta tcagtgataa cttttacgaa
    13561 accttgagca gcgtcagatg caatagcacg accgttagca gcaaagttaa acttaccgat
    13621 ggcaacatcg tatttctcac gggcttgttc ttctgtcaaa cctactgctg ctacttcagg
    13681 gagagtgtag atggctgcag gagtcaaatt caatttggca actgcatgat ttcctttaag
    13741 ggcattttca gcggaaactt cacccatgcg gaaagctgcg tgagccaaca tcttagtacc
    13801 gttgatgtca cctggtgcat aaatgcctgg aactgaagtt tccatgtatt cgttgacctt
    13861 gatacaacca cgatccaatt caaactcaac ctctccaata ccttcaaggt ctggcatacg
    13921 accaattgaa agaagagctt tgcttgcgat gatatcgtct tttccttcaa ccttgatacg
    13981 aagttgacca ttttcctcaa tgatttcttg cagtttagta ccagtcaaga tggtcattcc
    14041 tttacgctca aggatcaagc gaaggttctt agaaacttcc gcatccatag ctggaactat
    14101 acggtccatc atttcgataa cagtcacttt tgaaccaaat gtcatgaagg cctgaccgag
    14161 ttcgataccg acaactccac caccgatgat aacaaggctt tctggcactt cgttcatttc
    14221 aagaatgtca tcactagtca tgacaagtga agattccata ccagggacgt tgatcttgct
    14281 gacttttgaa ccaccagcaa gaatgatttt cttggtttca agcaattcag aaccatttac
    14341 caagacgttc ttgtctttag tgattgtacc aattccttta tgaacagtaa ctccgtagct
    14401 acgaagaagt cctgcaacac caccaacaag agtattaaca actttagatt tagtttctaa
    14461 aagtttttcc atatcaacag tgaagttagg attttcaatc acgataccac gatttgcagc
    14521 atgaccgata ttttcaataa tttcagcgtt atgaaggtag gtcttggttg gaatacatcc
    14581 acggtttaag caggttccac caagttcaga tttctcaaca agggcaacct taccgccgag
    14641 ttgggcagct ttaatggctg caacataacc agcaggacct ccaccaatca caacgatatc
    14701 aaaagcatca tcgctcttac catcatcgtt tgaggtactt gctacaggta cagggctagc
    14761 ttctggcgat gctgctccag ctgttgggat gttttccctt tcttcaccaa ggtaaccgat
    14821 aacttccgtt acagggacag tttcaccctc tcctttgaga atggcaatca agtacccatc
    14881 ttcttcggat tccaattcca tgctgacttt atcagtcatg atttccaaaa ggatttctcc
    14941 ttcttttaca aattctccga cttttttatt ccattggacg atttgtcctt ctgtcatatc
    15001 cacgccggct tttggcataa ttacttctaa ggccatgtct tccttccttt atctatatct
    15061 taaaaatgaa tactcttgct cttaaatcaa cattgagatt ggggtttcaa tcaactcttt
    15121 caagtccttc ataaacttag caccagccat accatctacg acacggtggt caatagttaa
    15181 tcctaaactc atgattgggc gaatcacaat ttcaccattg acgacaactg gcttctcgat
    15241 tgtcgaactg acaccaagga tagctgagtt gggttggtta ataatcggac caaaggactg
    15301 aacaccaaac attcccaaat tactgattgt gaatgttgaa ttttgtaact cacttggagc
    15361 caatttacca tccaaggtac ggccaataac atccttaaag gctacaacca gttctgaaag
    15421 actcatcttc tcagcattgt aaacaacagg tgtcatcaat ccattatcca tcccaactgc
    15481 catggcaaga ttgacatagt tgtgagtgat aatagtcttg ccatcttctg tcaatgaagc
    15541 gttgatgtat ggatgtttca taagagtctt aacaactgca agtgaaagaa ggtctgttac
    15601 agtagtcttc ttcccagttg cttccatgat tggctcaaga accctcttac gaagagccaa
    15661 catttcagtc atatcaactt catagttgag ggtgaaggtt ggcgcagtca agtaagattc
    15721 aaccatgcgt tgggcaataa ccttacgcat tggtgtcatt ggaatacgct cgatttcacc
    15781 atatggtgtt acgttatcag ggacttcttc cactttttca atctgagcag gagatttgat
    15841 gctatcgttt tcgatatttt caggaagcag ggccaaaaca tccttcttca tgattttacc
    15901 acgatgaccg gttccttgga tttcctgcca agcaatgtta tgttcgaggg caattcgttt
    15961 tgcaagtggc gaaatgcgaa ccacgtttgt gtctttataa gtttccacgt cttctttgtg
    16021 gacacgaccg tttgcacctg agccagaaac gtcgtagagg tttatcccta aatcatccgc
    16081 taactttcta gctgcaggag tcgctcttag cttgtcatca gccatgacct ctccaattct
    16141 atttatgata caaagggcgt caaaagcgac tgaaaaatag gaaatcgacg atggcttcga
    16201 tgaagccaag gagatttatc ttttttccga gcttttagcc cgtgctctaa tctaagatat
    16261 taatgacgaa gagctctgca cctaaaagat acaaagtttc tcgtcagctt tattttattt
    16321 acataactta tcttatgtaa ctctattctt tgttataagt ttttcggatt gcatctttga
    16381 tactttcaac tgttggaatc attgcatttt ctaggttttg tgcataaggc atcggcacat
    16441 cttctcctgc acaacggcga attggtgcat ctagatagtc aaatgcttct gattctgaaa
    16501 taatagctga aatttcaccg atatagccac ttgttttgtg ggcatcgttg accagaacaa
    16561 ccttaccagt cttcttcact gagtttatga tgatatcctt atcaagcgga acaagggtac
    16621 gtgggtcaac aatttcaact gaaattcctt cttctgctaa ttcttcagca gcttgaacca
    16681 cacggcgaag catttttcca taagtaacaa ctgttacatc cgttccttgg cgtttgattt
    16741 caccaacccc aagtggaatt gtgtagtctg gatcaactgg cacttcccct ttttggttaa
    16801 attctgactt gtactcaagt ataataactg ggtttttatc acggatagaa gacttaagca
    16861 ggcctttcat gtccgcaggt gttccaggtg ccacaacctt aagtcctgga atgtgagtaa
    16921 accaagactc tagagattgt gagtgctggg cggcagagcc aactccgtta ccagctgcac
    16981 aacgaacagt cattggaacc tgacctttac caccaaacat gtaacgtgtt ttagcagctt
    17041 ggttgacgat attgtccatg gcaataacag agaagtccat gaaggtcata tcgacgattg
    17101 gacgaagtcc tgtcatggca gctcctgctg ctgctccaga gatggcagct tcagaaatcg
    17161 gacagtcacg gacgcgttct ggaccaaatt cttcaagcat tccaacagaa gtaccgaagt
    17221 ctcctccgaa gacaccgacg tcttctccca tcaagaacac attttcatcg cgacgcattt
    17281 cctcagacat agcaaggata atggtgtcac ggaaggacat tgtttttgtt tccattttat
    17341 ctctttctcc ttagtctgcg taaatatctt caaaggctga ttcaagcggt gggaatgggc
    17401 tttcctctgc aaatttaaca gaagcttcta ctgcttcctt tacttgcgct tggatttctt
    17461 ccaattcttc ggcacttgca atgttatttt caataaggta attgcggagg ttttcgattg
    17521 gatctttttg tttccacaat tccacttctt cacgcgtacg atatttacca gggtcagatg
    17581 atgagtgacc gagccagcga taagttacac tttcaatcaa gactggacca ttgccactgc
    17641 gaacatggtc cacagctttc tgaaatcctt catagacatc gatgacattg ttaccatctt
    17701 cgatgaacat tccaggaatt ccataagcgg cgctacgttg atggatatgt tctatattgg
    17761 tcattttctt gatatccgca gagataccgt aaccgttgtt aatgcaatag aaaatgactg
    17821 gcaggttcca gatagaagcc atgttcactg cttcgtggaa aacaccttca ttggtcgcac
    17881 catctccaaa gaagcagaca acgattttac cggtattttg catttgctga ctgagggctg
    17941 caccgacagc gatccccata ccaccaccta caataccatt ggcaccaagg ttcccagcat
    18001 caaggtcagc gatatgcata gatccacctt tccctttaca ggttccagtg tatttaccaa
    18061 ggatttcagc catcattccg ttgaggtcaa tccctttagc aatagcttgc ccgtgtccac
    18121 ggtggtttga ggtaatcaga tcatctggat tgagagctaa catagccccc acgttagctg
    18181 cctcttcacc aacagaaaag tgcgtcattc ctggcacttt ccctttcttt actaattgtg
    18241 caatttttaa gtccatgcga cggatttctt ccatcttacg gaacatttct agcaaaagat
    18301 ttttatctaa agttgacatc ttcttgcctt tctaactttc ttcttacctt actattttac
    18361 cgtttttggc aaatactgtc aaagtttttc taaaagaaat ttcacaaaat aaaaaagaaa
    18421 accccgtgaa aacaagggat tttcttatca agaatatttt ttcacaaact ttttagcgtt
    18481 tggattttgc taaagattca aatctcttca taatcacagt taaacgccaa cggtagagcg
    18541 ccccactcac aatcaaacta ataatcaagc cgatccagta agaataagct ccaaaatctg
    18601 ttagagaatc aaatagcgta gccacaggga ttgctacgcc ccaataacca agcaaaccaa
    18661 ggtaaaaagg aataactgta tccttatacc cccgcaaaat tccctgaagc ggcgccgcaa
    18721 aggtatctgc taactggaag aaaagactat aagttaaaaa acgcactgtc aaatcgataa
    18781 attttgggtc gttaccataa agactggcca catttcccct aaaaatgtaa aggaaggtta
    18841 aggtgaaggc cgcaaaaatg agggcagtcc atcttcctag accaatatag gttttcgcat
    18901 catcaaatcg cttggctccc acttcatagg aaacgacaat agccatagcc gatgagatac
    18961 tcataggaaa ggcgtacata agacttgaaa agttcatagc tgactggtga ctagctataa
    19021 tcaaggacga aaacttagcc ataatcaagc caaccactga aaagatagcc acttccgcga
    19081 agacagttcc cccaataggc agacctaaac gaactccttc cttaatttta tccatattaa
    19141 gtggaattcg tttctcaagg tgtaaggctt tgagcttctc ctgtttaaat aaaaccagaa
    19201 cagaaatccc aagcaagacc cagtaggcca aggatgttcc taaaccagca ccagcccctc
    19261 ccagttctgg aacaccaaag gcaccgtaaa tcaagagata gttaaatccg ctattgagag
    19321 ggagtaacaa aagcatgagg tacatggaca gtttggtcaa gcccagcgaa tccagcaagg
    19381 aacgaatgac gctaaagagc aacaagggga taatcccgat agataaaaac caaagatagc
    19441 gaaccgctac tgccgctact gctgcttcta acccaatatg attcaagatt gttggtgcca
    19501 agaaaagtac catccccagc aataccacag ataggcccaa ggccaaataa ataaattggt
    19561 aaaaatcaga cgcaacttct tccttttttc ctcgaccaag atggtgacca atgataggca
    19621 ccaaggctga cacaatccct gttagaaatg taaagaaagg attccagata ctggttgcca
    19681 tagatacacc agccaagtcc atagtgttgt attgacctgt cattgcagta tcaacaaaag
    19741 aggcagaata attggcaaat tggtaaatca ggattgggaa gaaaattttt aaaaataata
    19801 ctaacttctc tcgtaaacac tttgtcttat acatacttct ctttctattc tgatttatct
    19861 aaaccaaaga gtttcagacc atagtttttc aaacttagcg gaggtttatt agattttgaa
    19921 gtagtatgcc aacacgcaca tgtacgacaa taatagcttc taactaaacc tccgttatca
    19981 tattgaaccg catggtcagc tttttcttta gtttcatatt gaattttgga acgattagct
    20041 gcgggacagt aaattccact attagatttc gcttgtctct ccctacgttt tcgaaaataa
    20101 ttcatattct aactcctatc aagcttgata gacgatttgt cccttacaga tggtatattt
    20161 aacctgccct tttaaggttt caccgatgaa tggtgaatta gctgctttgg aagcaaaatg
    20221 ggagtccaca aggcggtcag ccttggcatc aaaaatagtg atatctgctg gaccattctc
    20281 agccaagtaa cctgcttcaa agttgtaaag cttggctggg ttgtatgtca ttttttcaag
    20341 taattccatc aagctcaact caccagcttc tactaaatag gtcaagctga gagacaggga
    20401 tgtttctaag ccagtcatac cagatggcgc tttggtaata tcctcaacat ttttttcatc
    20461 tacatgatga ggcgcgtggt cagtcgcaat aactgtgatg acacctgatt tgagaccttc
    20521 gataacggca cgacggtctg attccaaacg aagcggtgga ttcatcttag cattgctacc
    20581 ttgtgttaaa aaaagtgctt ctgtcttaga gaaatgctgt ggcgctactt ctgctgtgac
    20641 ttctgcacct aacccctgag caaactccac tactttaaca ctttcttcct tagacaaatg
    20701 ctggatgtga acatgggctt tagttgcata ggcaatcatg acatcacgcg ccatcatagc
    20761 gtactcagcc accccagtag caccgcagat atggaaatgt tctctagcaa tattttcatt
    20821 aaagccaaga acaccgttca aacctggatc ttcctcatga aggctgataa aggtattgag
    20881 ttttttggct tcctccatgg cttccttgac aatcttactg ctctcaagcg gaataccgtc
    20941 atcagagaaa ccagccgcac cagcttctaa gagcgcctta aagtcagtca agtttttacc
    21001 attaaagttt ttagtaatgg tcgcaactgt cttgacatta atcttctctt tggcagctga
    21061 ctggagaact gcttgcaaag tctccacgtc tgaaatggtt ggactggtat tagccatcat
    21121 gacgacagta gtaaaaccac ctgcagcggc tgccagggca ccagtatgaa tgtcttcttt
    21181 atgtgtttga ccaggttcac ggaaatgcac atgaatatcg accaaaccag gagcaaccac
    21241 aagaccagta gcatcaatcg tttctgctcc ttcttccgtg atctcaggcg caattttgat
    21301 aattttccca tcttgaacta agacatcaca aacttgatcc aaaccagact tgggatccat
    21361 tacacgacca tttttgatta gtagcatctg ctttctcctt tattcataga aatcaacttg
    21421 ggtatccaac aatttatccc catcataaac aaacttggct gaaaagaagg gtttatcctc
    21481 taaaagccac tcaacaaagg tgtggtcacc ttcccaagtc ggcttgctca aaacctcatc
    21541 atagggaacc cattctagcg tcccctcatt gcagtcaatc aagtcgccct caaactccgt
    21601 caccttaaaa acataggtgt accagtctaa atctggtgta aattcaggaa aagtgatgac
    21661 accttttaga actggcttgg ctttgagccc tgtttcttca aggatttcac gcgccgcgca
    21721 ttcctggggc gtctctcctc tctctagctt accacccaca ccaatccatt tcccttcatg
    21781 gacatcattg ggtttcttat tacgatggag catgagcagt tctttcccat tatcaatgta
    21841 gcaaatcgtc gctaactgag gcatattttc tccttatcta agccaatcga ttggctcttg
    21901 tcctgtctct tttaagaatg cattggcctt ggaaaagggc ttggaacccc aaaatcctct
    21961 ataaaccgac aaaggacttg gatgggctga ttcgataatc aagtgatgag gattggtaac
    22021 taatgccttc ttcttacgtg cataagctcc ccagagtaca aaaacgactg gtctatctag
    22081 atgattgacc acctgaatca cagcatcagt aaaaggctcc cagatttgac cagcatgacc
    22141 attggcctgt ccagcaggaa cagtcaaaca agcattaaga agcaagactc cttgctcagc
    22201 ccaagctgtc aaatcatgag atttcttaac tccgatatca tctgacaatt ctttcaagat
    22261 attttgcaag gatggtggag ctgggataga gtcaggtaca gaaaaactca agccctgcgc
    22321 ttgacctggt ccgtgatagg ggtcttgccc tagaattacc accttaactt cttcaagcag
    22381 tgttgtcaag agagcctgaa aaaccttttc cttgggtgga taaataatcc cctgagaata
    22441 gacctgctcc ataaactgat tgattttccc gaaataaccc tcaggtaatt gcgccttaat
    22501 caaagcatgc caagacgagt gttccatagc cgactccttc atttttactg cctctattat
    22561 agcaaaaagt ggctatggaa accacttttt acagtttatc taaagattta ataaatcgac
    22621 tatatatacg atttgaatac gtgaatacag tttataaaga ctggctattt tttataatta
    22681 ctttttaaat cattaagcat tttactacct ctttcgaaga ttatcttttc tgaaatattt
    22741 ttaaacatat taaaatccat ttcagaaaaa ggagtttctt tagaaacttg ccatatagtc
    22801 tttaaataat ttttttctaa aaagtcgtca aaattagaaa aaaatcgaaa atacaatgca
    22861 ttctcttggt gtaaaatcgc tctttttaaa ggataatact ctttaatatt attaactttt
    22921 tgttcgtagg catattttgc tacatgatct aggtatatat caaaaaagtc atgaggaaaa
    22981 tctcccatac agccattacg attcatattg aggctatatt ttcgattagt aagataattc
    23041 ggaaatatat ttcctattac tctaagatta tctacttgtg aatcccttct cccaatataa
    23101 tccccttctt tgactaatga tggagatttc caagtaaaaa ttaaatcgtc agagaaattt
    23161 ttcttatcaa aaaacttaaa aagagattga taaatactat ttgctaattg acaagtgtca
    23221 gatgtaaatt cataattaac agcttcatta aaatcaactt cagacatttc aatgtactct
    23281 tcaatagtaa tattagcttt ttttgtagtc attagctaat ctcctttaaa atgtgatctt
    23341 ttcaagaata tttttatcta aacaatccag caagtcttgg taagaataga cttcgtaagt
    23401 cggctgggct tgtgtgtgat tttcgaggtg atgaggatta taccagatag tgtcaatccc
    23461 cgcattattg ccaccttgaa tgtcggcggt tagagaatct ccaatcatca gcgtcttttc
    23521 tttactaaat ccagcaattt gctggccaat cttttcataa aagagagcat ccggcttttg
    23581 agtttgcaac tgttctgaga taaagacttg attgaaataa ggtactagac cagattgagc
    23641 caaacgtcct gtctgaatgg cagtaatgcc atttgtcgca gcatacaagt tataatcacg
    23701 ctcaatgagg ctgtccaaga gatcatgagc gcccgatagt gtttgtccct gctgagcgag
    23761 ataaaattgg taacgctggg caagaaaact accgtctttt tcctgtccaa aatgagaaaa
    23821 taaacgagaa aagcgcgtgt taaccagctc ttgtttactg attttcttca gctccaagtc
    23881 tttccagaga gccttgttca taggaacgta ataatcttta taagcctgaa tatccgcaac
    23941 tccttcttct tttagaagtt gggtcaaagc cacatcctca gcagcatcaa aatcaagaag
    24001 agtgtggtcg aggtcgaaga gtagaaattt gtagaacaat ttgaggtttt cctttctgaa
    24061 aattcattaa gaacattata tcataaagca cctcatacaa ttaactaatt taatcactta
    24121 aaaaaaattc gaacactttc tatacaactg acagctcaaa tctttcagaa tagaacaata
    24181 ctaactatcg agcaccctgt cttcataaat atatgtgtaa ttctagacct agaattccta
    24241 taaactaaat gctttcatac tcttccaagt aattgattgc cttaaatttt aatttttgaa
    24301 ggattctaaa gctagaatag tcccatcaca atcagttttg attgattcac aatttagaaa
    24361 cactatagtt tcactcctgt taaaataaaa aggaactgca taaagcaatc cctttctgat
    24421 tttgaaatca tttacttaac attttatagt tgagataatc aatagcttac ctataaaaag
    24481 agttatagta aaattcctta tttattgatt tcaagctccg ctaactgtgt ttgaataact
    24541 gacagttctg caccagcctg aagaagagca gctgcattat aggcaccttc tacaattgga
    24601 accctgttga tgatgatact tttatcactg aaatcagtca ccatttttaa gttcatttta
    24661 gcagaaccta ggtcaaaaaa ggcaagtaaa gtatctgctg gattttcgga aacaacccta
    24721 tctacttgat caaaactcgt tccaattcct ccgccctcgg ttcctcctac ataagtaatc
    24781 ggaacatctt tagctacttt actaatcagt tcaacaacac cttctgcaat gtgtttggaa
    24841 tgtgaaacga taacaagacc aataccaata ctttccatca aaccacccca gtttctaaaa
    24901 tagcagtaaa gagtaatcct gatgagaatg atccaggatc aatatgtcca agaaaccaca
    24961 tgctcctaag acaagagcta acagactggc catcaataat agtattgttc tttttttcat
    25021 cattactcct taactagtgt ttaactgatc aattagccag taaatagttt atctttattt
    25081 acactatctg ttaagatata gtaaaatgaa ataagaacag gacagtcaaa tcgatttcta
    25141 acaatgtttt agaagtagag gtatactatt ctagtttcaa tctactatat tttgcacatt
    25201 ttcatgaaaa aaatgagaac tagaactcac attctgctct catttttcgt tttcccgttc
    25261 tcctatcctg tttttaggag ttagaaaatg ctgctacctt tacttactct cctttaataa
    25321 agccaatagt ttttcagctt ctgccataat agtattgttg tcctgggtgc caaatagtaa
    25381 attatttttt aatcctgtga gagtctcttt ggcattggac ttgataattg gatcctggat
    25441 ttttccaagt aaatcttcag cctctctcag tttttcttca accttttcag tctcgacctg
    25501 aggttcttct gattcctctg gtgattcttc ttctggttcc tctgttggtt ttggagactc
    25561 tggtttctcg ctttgcggtt tctcttctcg aggggtttct tcctcaggtt tttctgtctg
    25621 aggtttctcc tcgcttggtt tttccgtttg attggtatca gcttgaccat ttttgtttct
    25681 ttgaacatgg tc
//
LOCUS       DBERAE010000030        24720 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.30, whole genome shotgun sequence.
ACCESSION   DBERAE010000030 DBERAE010000000
VERSION     DBERAE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.30"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(345..977)
                     /locus_tag="ACL70N_001440"
     CDS             complement(345..977)
                     /locus_tag="ACL70N_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590224.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(979..1746)
                     /locus_tag="ACL70N_001441"
     CDS             complement(979..1746)
                     /locus_tag="ACL70N_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGS0590225.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(1797..3536)
                     /locus_tag="ACL70N_001442"
     CDS             complement(1797..3536)
                     /locus_tag="ACL70N_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS0590226.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDNNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            complement(3560..5668)
                     /locus_tag="ACL70N_001443"
     CDS             complement(3560..5668)
                     /locus_tag="ACL70N_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS0590227.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            complement(5665..6594)
                     /locus_tag="ACL70N_001444"
     CDS             complement(5665..6594)
                     /locus_tag="ACL70N_001444"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGS0590228.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            complement(6575..7279)
                     /locus_tag="ACL70N_001445"
     CDS             complement(6575..7279)
                     /locus_tag="ACL70N_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGS0590229.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            complement(7629..10619)
                     /gene="lanM"
                     /locus_tag="ACL70N_001446"
     CDS             complement(7629..10619)
                     /gene="lanM"
                     /locus_tag="ACL70N_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HGS0590230.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            complement(10736..10924)
                     /gene="pneA2"
                     /locus_tag="ACL70N_001447"
     CDS             complement(10736..10924)
                     /gene="pneA2"
                     /locus_tag="ACL70N_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HGS0590231.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(10931..11155)
                     /gene="pneA1"
                     /locus_tag="ACL70N_001448"
     CDS             complement(10931..11155)
                     /gene="pneA1"
                     /locus_tag="ACL70N_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HGS0590232.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKICISAAVSGIGGLVSYNNDCLG"
     gene            complement(11258..11428)
                     /locus_tag="ACL70N_001449"
     CDS             complement(11258..11428)
                     /locus_tag="ACL70N_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGS0590233.1"
                     /translation="MRKKRGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            11620..12483
                     /locus_tag="ACL70N_001450"
     CDS             11620..12483
                     /locus_tag="ACL70N_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0590234.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            12866..13486
                     /locus_tag="ACL70N_001451"
     CDS             12866..13486
                     /locus_tag="ACL70N_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590235.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            13572..14015
                     /gene="tsaE"
                     /locus_tag="ACL70N_001452"
     CDS             13572..14015
                     /gene="tsaE"
                     /locus_tag="ACL70N_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGS0590236.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            14005..14523
                     /locus_tag="ACL70N_001453"
     CDS             14005..14523
                     /locus_tag="ACL70N_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS0590237.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            14531..15547
                     /locus_tag="ACL70N_001454"
     CDS             14531..15547
                     /locus_tag="ACL70N_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGS0590238.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            15632..16888
                     /locus_tag="ACL70N_001455"
     CDS             15632..16888
                     /locus_tag="ACL70N_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGS0590239.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            16943..18109
                     /gene="recA"
                     /locus_tag="ACL70N_001456"
     CDS             16943..18109
                     /gene="recA"
                     /locus_tag="ACL70N_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGS0590240.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            18416..19786
                     /locus_tag="ACL70N_001457"
     CDS             18416..19786
                     /locus_tag="ACL70N_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS0590241.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     YIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            20162..21118
                     /gene="lytA"
                     /locus_tag="ACL70N_001458"
     CDS             20162..21118
                     /gene="lytA"
                     /locus_tag="ACL70N_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS0590242.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            21496..21657
                     /locus_tag="ACL70N_001459"
     CDS             21496..21657
                     /locus_tag="ACL70N_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0590243.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            21644..21850
                     /locus_tag="ACL70N_001460"
     CDS             21644..21850
                     /locus_tag="ACL70N_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590244.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            21896..22249
                     /locus_tag="ACL70N_001461"
     CDS             21896..22249
                     /locus_tag="ACL70N_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS0590245.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKCY"
     gene            22383..22808
                     /locus_tag="ACL70N_001462"
     CDS             22383..22808
                     /locus_tag="ACL70N_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590246.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVKEFSLEYMTTGDILVEAFKA"
     gene            23216..24206
                     /locus_tag="ACL70N_001463"
                     /pseudo
     CDS             23216..24206
                     /locus_tag="ACL70N_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24196..>24720
                     /locus_tag="ACL70N_001464"
     CDS             24196..>24720
                     /locus_tag="ACL70N_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590247.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYSLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSV"
BASE COUNT         8081 a         4135 c         4298 g         8206 t
ORIGIN      
        1 ttgagagagg tatgaatgat ttgggataaa gatagttttc ttttaaaacg gttgtaggag
       61 gaaaatctct cctacactat tattgattct gagagaaaat tgcaaaatat catctaccaa
      121 actttcaatt attaagattt tttgcagttt atctgaatta gaatcgcaag gcttctcaat
      181 aatataattg tcgaattttt tcattctaac ttcctctcca ttatttcttc ctttatcaag
      241 aaaaagttac ctcaatatta ataaagtaca attctaaatt aactccaatt cttgattcat
      301 gataatattt cagtaactca tcgtgcaatt aaaaacaagg atttttattt cagatgatcc
      361 atcgtgaaca cttcatcagc catctcccaa attgccggat tatgtgttgc gataatgatt
      421 agcctattat catctcgaag agatagcaaa atctccataa tcaactgaga ggttgctggg
      481 tctattgaag ctgttggctc atctgccaga ataaagggtg gattctttaa gataattttt
      541 gccaaggcaa cccgttgcga ttctccgccc gataactcaa agatgcgctt atctaggtca
      601 agataagcca ggccgacctg ttctaaagcc tgcttctgcc tcaaccgctg ttccgaccga
      661 ctcaactttt gaccaatgag acctagctta aggttttctt caatactttg gttttcaatt
      721 aagccaaagt tctggaagag gtagcccaat tcgtgacgga aaaaatcact cgatttataa
      781 ttggccaagt ctttacctcg gtaaaaaatc gtcccatcat aaggttctaa tttcccaatc
      841 atgttcatca aggttgtttt tccgctacca cttgaaccaa ttaaggcata gacttttcca
      901 gcctcaaatg tcattgaaag attcgaaaat aactctcgtt ctccaaaaga tttactcacc
      961 tgtttaagtt caatcatatt aacctccctt caaaacaaga atggacatct tgttttcttt
     1021 ctgcatttgg acatgtaact gtaaaagaga tagaccagta aagagtaaca agactaagaa
     1081 agcaactcct atctctacct gaagaaatac actcgcaaca aatcccagta aaaacacacc
     1141 cagttgagca aagagataag tgcgatggat ttctaagaac ctgagacctg caatgcgttt
     1201 gataaaaatg gcacgtctaa attcttcaaa gtagagccta ttcatagtgt taaacaacaa
     1261 gattgaagtt gcaatcccaa gcacagctcc tgctagcatt acccaacgtt ccctctggat
     1321 attatccaat aatgtgatgt agttgtggta acctgtttgc atttctgaga cccaattttc
     1381 aatgccttgt ctctggataa gctcctgggc atcagacaat tgattaaaga gaacgtagtt
     1441 ctgtactgcg tctatccaaa acaaaatgga ctgtggacca gttgattggg gtgttataac
     1501 aatgatgatt ggatctttca aaaactgctg gtaagaaata ggggtcgtat tatacacaaa
     1561 acgatcctga cctgattcta aataacctac cgtagcagtc atttgctgtc gttcatcttg
     1621 actagatatg cgactggtta agtcgtcttc aaaaacagat ttataatgtt cttcctctga
     1681 acggaggtgt tcaggcagca ataagacaaa ctcccctaca tcaaggtgat tcatcttttg
     1741 actcatttta gttgaactgt aggacttact ttttcagagg gctccaaatt ttattttcat
     1801 ttactttttt tagcccataa aatatttacc atacttataa aaagtagtaa tactccaact
     1861 aaactgactt gtaatgaatt atatgtattt tctgaagtgt taggtaaata attttgagag
     1921 tacccttctc gggcaatagt aataatattg tgtgtgttta tttgtttaat tccaatagta
     1981 gtttgaattc tctcttccaa ctcaattaaa ttaacattat ctatgaaact atcccaactt
     2041 tgttcatttt tatattctaa ttgtaacata ttcaaatcat atctcaatac gtttggtata
     2101 tttaacactt ttataccatt ttttactggt aatgtttctt ccagaatttt ttttacaaac
     2161 atataattat agggctgatc ttttaatttg tatttatcaa taatcattgc aatcgcacca
     2221 gaaactttag gagcagcaaa tgagtttcca taaagatacg tatatcctcc tagtgttgcc
     2281 gaaaaaatcc aatcttcttt atatttttct gcattaataa agttattaag tcctaattct
     2341 gaaagagata atgttgagcc tgcaggcgca tatattgcat cagaatcccc tttattgcta
     2401 aaatctgata aattacctaa gcgatctatg cctccgaccg aaattgtaga tgagaaataa
     2461 cttggaacat caactactaa tcctggtttt cttacttttt tgcgtgaact aataagtttc
     2521 aataaatctg actgatttga tacatttagg gagtcattcc ctaatgcagc tactataatt
     2581 actccttttt gattcgcgta atcaatagcc tttttatact tcaaaaatgt ttcaaaatca
     2641 tttgttccgt cctcatattc tccatcaatc attaaatatt gtccagtact aagattgata
     2701 atatcattgc catcatctac agcatcaaaa attgctttta caatccaatc tggactagct
     2761 gacgacttac caaatattct atagacgtta atattaacgt gaggatttac tccattaata
     2821 ttgttatccc ctacaatttg agctacaaca gccgtaccat gacctaatct atcttgaata
     2881 tctgatatta ttccttcctc tccctcctct tttcctaaat atcctttatt ggggacatag
     2941 ttttttgagt gatttgaaag atttttcagt aatccagtat tttgtaaatc gactcctgaa
     3001 tctaaaatag caattgaaac tttagaatta cttttagaat ataatttata actttcgcct
     3061 ccaccagtaa ctttatctat atcccattca tattttctta caatcgacga ttctaagtta
     3121 tctttgtcat gctctatatt tcctcctcta ttatctagat gagaaacatt ttccttaatt
     3181 ttattatcta aattatcttc gcctagtaaa ttattacttt cagagttaac aatatcgtta
     3241 tttatttgtg gttcaagttc caatttacaa cagttttttt ctaaatgttt atctgttgtt
     3301 acaaataatt ctgtcttatc gatttgaata cgaaatttat tttggtctac ttcttcttga
     3361 tttttattag aatagtcaac ctgtttttca tcagattcag aaaaactttc gctagtctga
     3421 gtgtgagtta tattgccatc aagattttta ggtatttctt gagcagtaac agaattattg
     3481 aacaaacaaa agaataatat cgctaaagtc caatattttt ttttcataat cttcataaat
     3541 ttaccctttt aatcaaaaac taattatttg aatacaattg cttataaatg cctcctagtt
     3601 caagaagttc tctatgggtc ccaatctcta caatttcacc attatgcatt actaagatct
     3661 tatctgcaga cttgatagta tctagtcgat gggcaattaa aatcttagtg gtaccgattt
     3721 cacttaagta agaagttgta atttgttgag ataaattatc taaactactt gttgcttcgt
     3781 ccaaaacaac taccgaaggt ttcgacaaaa gacaacgagc taaaagtatc atttgctgct
     3841 gccctccaga aaagttatta ccttcttcag cgatgattgt ctctaatcca agaggtaaag
     3901 atttaactac attgctaaga ccaattgaat ttagatttgt cattaattct tcatctgaaa
     3961 caaagtgtcc aaatgtcaaa ttctctctta aggtaccata acttagggtt gaattttgta
     4021 acactgctcc aaaaatcttt ctatacaatg tttgaccaat ttcttctttt tctactccat
     4081 caacttctat tgaaccaata ttaggttcta ataaacctaa taaaatttta gctaatgtac
     4141 tcttacctga acctgattct ccaacaatag caacagtttc tcctttttta atagtaacat
     4201 ttattccttt caaaacataa tcatcaaata atccatattt ataccaaata tcttttaatt
     4261 ctattttttt atcaaatttt atatcttgac tgactctttc tggaattaat tcggatttag
     4321 tattaaacac atcctctatt cttaaaaaat atccctttaa taacattaat tgtatatagt
     4381 tatcacttaa agaaattata ggagaaataa agtatggtga gactgtactt attgctacaa
     4441 tttgtcctaa cgtcaattgt tcgaatgttt ttatatttac acctacaata agggtcaaaa
     4501 cagggagaat aatttgtaaa acattcgtta tactactaac aattgataaa tgtatatcaa
     4561 gttttcgacc tatgatgagc tgttttgtat taaaattatc ccatttgtta atccaaaatt
     4621 cctcttctcc agttagctta atatcactat ttttagaaat tacttcggaa gtaatatttt
     4681 gaacattaac cttttctttt atatttttat caattaaatt ttttgagatt tttatgattg
     4741 gatacattac aatagataga gctagactta gtgatattaa aaagattacc atgtacttag
     4801 aaaagctaaa taaaaccaca gcataaacca caatcattaa caaatcaagt atagctgcta
     4861 taaaattatt tgatagtatt tctcttatat aaacaataga gttagctcta aaaagtatat
     4921 cccctaaagt acgtttttca taaaaactgt aaggtaaata tatcaaatgt ttcataaaat
     4981 catagctaat ctctttatcc attatatatt ttaaggatgc aacatatatc tgtcttaata
     5041 aatacattag tgagaatgaa acagtaaata taaataatat agtaaataac attctagacg
     5101 aatacgaatc gtccttgaaa ttcgtgtcaa ttatgtatct attagctata ggtactaatg
     5161 attgtattac atacaataat gctgttacaa aaaataaaat ccctagctta ttcctatact
     5221 taaaaaaata ctttaaaaca ggcgacttct tattatcttt acgagacata aagctatcta
     5281 actttttaaa tgttaaaatg atatttgaat aatgcctttc aaattcactt attgacattc
     5341 tctgcctgcc ttttgcagga tctaaaatat aaaacttgtt tttactaatt ttttcaagaa
     5401 taataaaatg agaactctcc cagaagcaaa tgagtgggaa actgagcggt tttaaatctc
     5461 ttaccgaagc tttaaaagca tgagaactta tattaaaatc tcctaaaact ttacttatag
     5521 ataggagaga atatccagat ctggatgatg ggtagatttc acgtagttca tttaaagaaa
     5581 tctcatattt aaaatagttc aatatcatgg cacagcatgc taatccacat tctgaatttt
     5641 ccatttgata tatcattgga attttcacaa tacttcctcc ttgttcaaaa taaagtcgat
     5701 aatttcttct tgtctaaaat ctactaattt ctttagatac ttaatctttt ctaaatattt
     5761 attatttttc gagtaaatat agtttgacaa ggtaaaaaca acttcttcta aagataagtt
     5821 ctgtggaata atccaatcag aagatttatg tagtaattta tagtactcat ggataatatt
     5881 ttcctgaata tttgaatcaa aaacttcatg attagcaatt gtaaatgctg acccttcacc
     5941 tttcacttca aagtaaaggt ttatcaaaca tttttcaaat tttgaaaaaa aagatttttc
     6001 tttagaggtt aattttgcaa aatcgtcgat tgttatataa ggattattat agagactgtt
     6061 cgcaaagaat ctctgatatg tttttgaatc ttttgaatac aaaactatct ctctaatagc
     6121 attgccatct gttccatcaa ttggtaaaca taccgtaact agaaaaagaa ttatattcaa
     6181 aataaaaaat tctgatgcgt acggcacaaa tcccaaaagt gctaatattg cgacaattag
     6241 gttagctcca cctcccccaa agaagtagaa caccaaattc ctatcactat ttttttcatt
     6301 agtaatgttt ctattactca tttgacaata accgaatgct aataacactg gaaatttgaa
     6361 atatattttt tttctgaaat agaagaaaaa gggagtagca agcatctcta gtttataaga
     6421 taaacatctt cccactaaaa aatgacctag ttcatgtaat gtaattgata ttaacgaaat
     6481 taaaatcaat cgaaaataat agattaatga atcatttgga aaaattatca ataataggaa
     6541 caataacgga atcaaacata aatatatgac agagttattt aatattttca acataatacc
     6601 attcctctaa actattagct tcaaaaaggc gttttttctc ccaatacatc ttctcaaaat
     6661 gttcggaatc ataattttct aaaattaatt ttaatgtctg gtaagctctt tcttgataat
     6721 ccgttgtttt gtacttaatt ttcccttcaa gtacatcttc aattttataa gttgcctcca
     6781 tcaactgagc ctctgcaata tctttgagtg aattggtaat tgaaacttgg tgtaatatct
     6841 gtcctcccat atatgaaaat atatctctaa gatattctga cacattatca gagccgttac
     6901 tctcagcaac atctaatgtt acaacaaact ttccagctaa tcgaaaaaga tggctccacc
     6961 ccccaatcct ttcaataaag ttttttgtgt ccacagatac gttttgtaaa tatacaggag
     7021 aagagataat tataatatca gactctaata actctttttt tataacacct ccatcatcag
     7081 cattactttg cctatcaatt cctttcttaa acaactcttc tgaatcagaa ttagatattt
     7141 ctagctctga attgaaaggt gtcctgaaag atatatcaac attatttcta ctagaaatga
     7201 tacttgaaag tctcttagta tactctaaag tcttagagtt atgatttcgc actcctgcat
     7261 atataaatat tttattcatt ttaattcatc ctctcaattt gaatttagta gatttttcaa
     7321 gatagtatgg tacaaaaaca gacttttgtt gactcacatt attacatatg ttttgtatta
     7381 aaccaaaatc aatactattt ttggagtaat tttgatttta gtttaaaatc atttctataa
     7441 cagtagcata tacctcaagc cgtttagcaa ttagaataga acctttcttt attatattat
     7501 tatctcaacg aaaagctaca ctattaaaaa tattttatag aattacatat taaactagtc
     7561 aatcttggta tttttatatt gcttaatgag tggacacctc tattttagaa acaaaactat
     7621 aaattaagct agatttcaag taatgagggg ataactatct ttttgtcatt ctgattcagt
     7681 gcgatatacc ttaaaaaagt ataagcaata ccagtcacac ctgtatacaa agaaaaatct
     7741 gggaaattgc ttgtttggac gatacgatac tctccttctt ttgatttatt cattacaaca
     7801 ctacacaata aagactccaa ttccatacta gtatccattt ctttcatgta gtcgatgtaa
     7861 aaatttatta tggccatact tccatggcaa aatgtatcat tatctaaact agctacaatt
     7921 ccctctggaa cactttgggg atgattaact aatgtcccaa attctccact acaccacttc
     7981 aaagaatgaa ttttgatttt ctccctagga actagttgta aaattaattc tttatatttt
     8041 ttaagtcttg tcactttata aatatttttt aatgtaaaaa ttacacctga tagtccatgg
     8101 ccaaaactat atccaaaatt actattatct ctctcgctta catcattata tagcgtatca
     8161 cctaaactta atactagcct tagaacacgt tccttctcta ttcctctcct ataatatctt
     8221 accagtgtat taattaaagg tagaagacca ttaatatagt cagacttgtt tgaaacactt
     8281 gcaaaatcag tcttttcaag ctcagttaaa acactcttta tataatttaa gcatgcgaga
     8341 gtatttgtat cgtaatcctc tataatggat agaacaatga aatatcctat atccccagtt
     8401 aaaccaaatg tggtcttaga taaagaaaca gatggcggaa ttgcagataa cattttattg
     8461 tacagttgag tatatgatga tttatctttc aataatttta catagtacat aaacagtaat
     8521 attccagctc tacccctata catatcatta cccgtttgtt caagacacca tttagaacct
     8581 ttaaaattaa caggtatact ccaaattgga tattcgtcat aaatattatt aataaccaaa
     8641 gagtctgcaa tattttctac ttcattatgc agaatagtaa ctaaactttc atttgggagt
     8701 ttttttctat tagataagtt taatttatat cctttttttc gctgatcaaa gcttggaaaa
     8761 taaatttcaa tgatatcaag ttgcttttct aaattttcca aattattatt aggtaaatat
     8821 ttcataaaat agtcatatcc agaaaattga tgtagggaaa taaaatgatt tccaaaatca
     8881 tcgtagattt cattgatatt tgtatctgta taaaaaatcg gaatatctaa taacctcatt
     8941 tgttcacatt cgcttgctac aataccttga ttagaaaact tattgctcca gagattttcc
     9001 aatgcttttt ctctatctaa catttcttca taaaaatcag gatgatataa aaaagatagt
     9061 actgaagcat agctatttgt gtctctaaaa agtacccttg tctttaaacc atacaagttt
     9121 gcttttaata gcattttaaa ttcttctgtt ttatttaact cttcaaatat cagataaaaa
     9181 tccctaaaac cttttttgaa atcttttata tacttatcaa attctatatc accatcccga
     9241 acaggcaggt ttttcccacc ttcaaaatca attttcccaa tatcaaactt taccttatca
     9301 gtatttaaat taattaaaac ttgaccatta aaagcatcct tcttaaaatt tcctgtaaga
     9361 gcactcatct caacatcaag accatcctcc ctttttactc cctctgttgg aagaagcaaa
     9421 gttcgagtca ccctgtgaaa cagggtatcc agcaaactct gaccagtttt atcatcaaat
     9481 agaggttgct gtaacattgt ttcaaagtct attattacag gcatatctcc ataggaaatt
     9541 aaattttcaa aatgtatatc actcccatta aataaatata taaatgctaa aagcacacca
     9601 aaattataat aatattcagg taattttttc ttttgctcta gaggtagata atcaataaat
     9661 tcttcatagc tgtgatccga ataagcaata gttcgaggta ttcttatcct aattttttca
     9721 tcaacctttc ggatatactc agcaatagta tttagtgagt tattgattat taaattttta
     9781 ggcttgtaaa caattttcgc gtcatcaaag aagagtatca aaacagtttt tccttggctg
     9841 tgtgtatcac cctttccaaa ttttatatca tttaatttcc cccttagccc taattcttct
     9901 tctagcacac taaaatcatt ttctaaattt gataaaattt ctataaaata agtatagaac
     9961 cgaagacaag actccgatat ttgcctcagt aaaacgggat atttgttata aaaatttaat
    10021 atattctctt ccttgtcaaa caatgttata aaatatttgt accgttgctg ctccgattcc
    10081 ccttcaagta aacctttttc acgcaatgaa tttatctcta aaaccaaagg tttaacaatc
    10141 caaggataga ttaaatcttc taaataaaat actagagagg aaaaaatatt tccattcttg
    10201 tcaatccact cgtattcttt attctctaga taattattga ttaatttaag caaattaata
    10261 ataaagggtt ccaaaattct agaaaaatct ttcttaaaat taattctttg gggatgtttt
    10321 ctaaatattt caaatgaacc ctccgcaaat ttataccatt ccgaattttt ggcatattct
    10381 gaatatagtc ttatctgttc ctcggtataa tcatagttca cagtgttaga aaatattttt
    10441 ttattgtaat tatttaattt caacatttct tcaaaagttt tttcagaaat aattgacatt
    10501 gtagaacgcc aattatttaa tgaaaagtta tttaaggaat tatcatttcg ttcagataat
    10561 atttgatatc tttccttaat aaacaatgtt ttatgcacat ttttaatttt atatttcatt
    10621 tacttacctc aaacctatac gacttactat tgttttaaaa aaaaaacctc tctcaaaatt
    10681 attagttacg agagaggaaa ataaagagca acttttattt ttaaaattga atattttatt
    10741 ttttcttgtt gtctttgcca caacgagtct gagctgaccc caaatatgat gcaataaaac
    10801 ttaatgtagc agaacatata attgttgatc tagggtcagc accatctgtg ccaccataaa
    10861 ccaattgcat ttcttcaaga gataattctt tcaaactctt tccgattaca aaatcatttt
    10921 tcattttaat ttaccccaaa caatcattat tgtagctaac tagcccccca ataccagaaa
    10981 cagctgcact aatgcatatt ttcgagctag ctgcagctga tttcaaaata ataggagtag
    11041 gcgtccaacg tggctctgca ccatcagatg caccataaat taaactcatt tcatcagcag
    11101 acaatgattt taaacttttt ccacaaaatt tttcgtttga attaaagttg gtcataagta
    11161 ataactcctc cttataaaaa gttaaataag ttgctctata tttttcgttt tttcagataa
    11221 attataattc tctcattctc gtgcaaaata tcgggtttta atccgccttc ccaacatcaa
    11281 gaccattgga cttcttttgc gattgcactc gaatctccaa ttgtttattc ttctgaataa
    11341 actgttggta aggaattgta ttactaaaca taaaaacacc tagcaatgca aatgtaacta
    11401 attttttaat tccacgtttt tttctcatgc aatgaaaccc ctttcttttt ccttgttttt
    11461 attctaacag atatatttta tttagtcaag tatttttatg taatttttaa cttttttttt
    11521 tgtttattac cataaagaat tatttattcc tttaacttgc tattttgaac taaaaacttt
    11581 ataatgaaat taagcaaata ggaaggttta ttatctttaa tgaatacact cgcagagaaa
    11641 ttcagattga aaagaaaaga gttgagactc tcccaacaaa ctcttgcaga aggaatttgt
    11701 gaacaaagtc agattagtaa aattgagaga gggcatttca ttccctccgc agaccttttg
    11761 ttcaaactct ctcaacgact tgaagtacca ttagattatt tttttaatga acaaattgaa
    11821 attaaatcta acctctctaa tttcaagcaa ttgtctgctc gactattaga cgatagaaat
    11881 tatgacgatt tggaatatat ttatagaata gagattgaac gaagtacttt tctaacacta
    11941 gaagaccgaa cttatcttga atggattaaa gctattattg acttttatca atatgacagt
    12001 aagtgtgaag caatttcttc attggaaaat atattattaa aagtctcctc aaatactctg
    12061 atttatttaa aggcgttgaa tactctatct aatttctatt ccttagtggg tcgtgaacaa
    12121 gaatatgagg caaactactc tcatttaata gagttgtatc agacaaaaaa tttggaccat
    12181 caagagtttt tatttggcta catcagagtt cgttacaact acgctcacta cctagtatca
    12241 aaggaaaaat ataatgaagc catccaagaa gctcttgaga cgattgaact ctgtaaacaa
    12301 agacagacaa gctaccaact ggctcctcta cttattcttg taggaaatgc tggagccaaa
    12361 tttctagaca gagaacaagt caaaaattat tatatagaag caaaagagtt atgtaagatt
    12421 tataacaatc ctttaatgct gatgaagata gaaaattatt tgaaggaatt agatactgtt
    12481 tagttaatct tgacattata gtttttctga aacgttaaat aacctgtaag gctgatagtg
    12541 aaatgaatac tatcagcctt atgattatgt gactattagt tcgtctcgct ccgttaggtg
    12601 cgagacaaaa aaaacacccg ctagacggat tttcatgatt tcaaatttat attcttcgaa
    12661 aatctcttca aatcacgtca gctctatctg caatctcaaa acagtgtttt gagcaacctg
    12721 tggctagcta cctagtttga tctttgattt tcattgagta ttagtctcta gtgtttgttt
    12781 agcgtcttaa agagacattt gagaagatta gaaacagttc tctcttttct cctagtataa
    12841 tgattggtag gaagggagag agaagatgaa atcaatgaga atcttatttt tgttagcttt
    12901 aattcaaatc agtttgagta gctgtttcct atggaaggaa tgcatcttgt cctttaaaca
    12961 aagtacagct tttttcatcg gaagcatggt tttcgtttca ggaatctgtg ctggagtaaa
    13021 ttatctttat acccgtaagc aagaagtcca tagtgtccta gccagtaaga agtcggtgaa
    13081 gcttttttac agtatgttac tcttaattaa tttgttagga gctgttcttg ttttgtcaga
    13141 taacttgttc atcaaaaata cgctgcagca agaattagtt gactttttat tgccatcctt
    13201 ctttttccta tttgggctag atttgctgat ttttttaccc ttgaaaaaat acgtgcgcga
    13261 ttttcttgct atgctagaca gaaaaaagac agtgttggtg actattttag caacacttct
    13321 tttcttaaga aatccaatga ccattgtctc acttctgatt tatattggac tgggcttgtt
    13381 ttttgcagcc tatcttgtcc caaattcggt taagaaggaa gtttcctttt atggtcatat
    13441 tttccgagat cttgtattgg tcattgttac gctcattttc ttttagagaa agcctgtttt
    13501 ttatggatgt tatgatgata agtttagtag gaaaatagac acaaaagaaa agtttttggt
    13561 ataataagag tatgtacaca aaaaatgaag aagagttgca agccttaggg gagcgtttgg
    13621 gccatctatt agcaaagaat gatgttttaa tcttaactgg agaactgggt gcaggtaaaa
    13681 cgacctttac taaaggactt gcaaaaggat tacagatttc tcaaatgatt aaaagtccca
    13741 cctatactat cgtgagagag tatgaaggtc gacttccact ttatcaccta gatgtttatc
    13801 gtattgaagg agatgctgat tctatcgact tggatgagtt tatctttggt ggcggcgtga
    13861 ctgttattga gtggggaaat ctcttaggag atgccttgcc agatgcttat ttagaattgg
    13921 aaattctaaa agaagcagat ggacgccgtt taaattttca ggcaaagggt ttgcgtgctg
    13981 agaaattgtt agaggagctt caatatggag tatgaattgc tcattaggga agcagagccc
    14041 aaagatgcag ctgaattagt ggccttttta aatcgtgtga gtttggagac agactttacc
    14101 agcctagacg gagatggtat tctcttgact agtgaggaga tggaaatatt cctcaacaag
    14161 caagctagtt cggacaatca gataacctta cttgcattct taaatggcaa aattgctggt
    14221 attgtaaata ttacagctga tcagcgtaag agagtccgtc atattggaga tctcttcatt
    14281 gtgattggaa aaagatattg gaataatggc ttgggaagtt tgttgctaga agaagcgata
    14341 gagtgggcac aagcaggtgg cattctgcgt cgtctccaac tgactgtcca aactcgtaat
    14401 caagcagcag tccatcttta tcaaaagcat ggctttgtca ttgaaggtag ccaagagcgt
    14461 ggggcatata tagaagaagg gaaatttatc gatgtttact tgatgggtaa actgataggt
    14521 tagtagaaat atggttaaaa aaattattgg aatggtgcta gctttacttt ctgtaactgt
    14581 agtaggagta ggtgtttttg cttatactat ttatcaacaa gggacagaaa ccttagctaa
    14641 aacctataaa aaaatcggcg aagaaaccaa ggttattgaa gcgactgaac ctctaaccat
    14701 tctgttaatg ggagtggaca ccggaaatgc tgaacgaact gaaacttggg tcggtagaag
    14761 tgatagcatg atcttgatga cagtgaatcc taaaacgaaa aaaacaacaa tgatgagttt
    14821 agagcgggat attctgacgc gcattgaatc agggaatggt caggctcatg aagcgaaact
    14881 gaactcagca tatgcagatg gtggagcaga gcttgctata gaaaccattc aaaaaatgat
    14941 gaatatccat attgatcgct atgtaatggt caatatgaga gggttgcaaa aactagtgga
    15001 tgcagtagga ggtattacag tcaataatat cctaggtttc ccaatttcta tcagtgacca
    15061 agaagaattt aatactattt ctatcggtgt tggggagcaa catattgggg gagaagaagc
    15121 cctagtctat gcacgaatgc gttaccaaga tcctgagggg gattatggtc gtcaaaaacg
    15181 tcaacgtgaa gttattcaaa aagtcatgga aaaagctctc agtttaaata gcgttggtca
    15241 ttatcaagag attctaaaag ctttgagtga caatatgcag accaatattg atttgtctgc
    15301 aaaaagtatc cctaacttgc taggctataa agattcattt aaaaccattg aaactcagca
    15361 gttgcagggt gaaggagaga tacttcaagg tgtttcttac cagattgttt cgagagcaca
    15421 tatgttggaa atgcaaaata tactccgacg ttctttggga caagaagaag ttactcagct
    15481 tgaaaccaat gcggttttat ttgaagattt atttggcaga gcacctgttg gtgatgaaga
    15541 taattaactt ttgatacaaa taaaaaaatc aatcgtagga aaattcctgc gattttttca
    15601 aaaaaatacg aatagatagg taggaggaaa catgaaagca gaaatcattg ctgttggaac
    15661 agagattttg acaggacaga ttgtcaacac caatgcccag tttttgtcgg aaaaactagc
    15721 tgagattggg gtagatgtat attttcagac ggctgtagga gacaatgaag ttcgtctctt
    15781 gtctttgctt gagattgcca gtcaacgtag cagtctggtg attttgacag gcggtttggg
    15841 gccaactgag gacgacctaa ccaaacaaac cctagctaaa tttttaggga aagcattagt
    15901 ctttgatcct caggctcagg agaagttgga tatctttttt gccctgcgac cagactatgc
    15961 ccgaacaccg aataacgaaa gacaagctca aattgtagaa ggagcgattc cactgccaaa
    16021 cgaaacagga ctggctgttg gaggaaaatt agaagtagac ggagtgacct atgtcgtcct
    16081 tccaggtccg ccaagtgaat tgaaacccat ggtcttaaac caacttctac ccaagttgat
    16141 gacagggagc aagctgtatt cccgagttct tcgtttcttt gggattggcg agagccagtt
    16201 ggttacgatt ttggctgatt taattgataa tcagatcgat cctaccttgg ccccttatgc
    16261 caagacagga gaagtcactc tacgtctgtc aacaaaggct agcagtcaag aagaggcgaa
    16321 tcaagcgctg gatatcttgg aaaatcaaat cttggactgc cagactttcg aaggaatttc
    16381 tttacgagac ttttgctatg gttatgggga agaaactagt ttagccagca ttgtggtaga
    16441 agaactgaaa aggcaaggga aaaccatcgc ggctgcagag agtttgacgg caggtctttt
    16501 ccaagctacc gtggcgaatt tttctggagt ttcaagtata tttaagggtg gttttgtgac
    16561 ctatagcttg gaggaaaaat caaggatgtt ggatattcct gccaagaatt tggaagaaca
    16621 tggtgtggtg tctgaattta cagctcagaa gatggctgag caggcacgaa gcaagaccca
    16681 gtctgatttt ggaattagtt tgaccggagt ggcaggacca gatagcctag aaggacaccc
    16741 agttgggaca gtcttcatag gcttggcgca agagcaagga actgaggtta tcaaggttaa
    16801 tattggaggc agaagccgag cagatgtacg tcatattgcg gttatgcatg cctttaacct
    16861 agttcgcaag gctttattaa gtgactaact tttgatataa tagtagatag gtctgaggat
    16921 cattagaatg taggagaata gaatggcgaa aaaaccaaaa aaattagaag aaatttcaaa
    16981 aaaatttggg gcagaacgtg aaaaggcctt gaatgacgct cttaaattga ttgagaaaga
    17041 ctttggtaaa ggatcaatca tgcgtttggg tgaacgtgcg gagcaaaagg tgcaagtgat
    17101 gagctcaggt tctttagctc ttgacattgc ccttggctca ggtggttatc ctaagggacg
    17161 tatcatcgaa atctatggcc cagagtcatc tggtaagaca acggttgccc ttcatgcagt
    17221 tgcacaagcg caaaaagaag gtgggattgc tgcctttatc gatgcggaac atgcccttga
    17281 tccagcttat gctgcggccc ttggtgtcaa tattgacgaa ttgctcttgt ctcaaccaga
    17341 ctcaggagag caaggtcttg agattgcggg aaaattgatt gactcaggtg cagttgatct
    17401 tgtcgtagtc gactcagttg ctgcccttgt tcctcgtgcg gaaattgatg gagatatcgg
    17461 agatagccat gttggtttgc aggctcgtat gatgagccag gccatgcgta aacttggcgc
    17521 ctctatcaat aaaaccaaaa caattgccat ttttatcaac caattgcgtg aaaaagttgg
    17581 agtgatgttt ggaaatccag aaacaacacc gggcggacgt gctttgaaat tctatgcttc
    17641 agtccgcttg gatgttcgtg gtaatacaca aattaaggga actggtgacc aaaaagaaac
    17701 caatgtcggt aaagaaacta agattaaggt tgtaaaaaat aaggtagctc caccgtttaa
    17761 ggaagccgta gttgaaatta tgtacggaga aggaatttct aagactggtg agcttttgaa
    17821 gattgcaagc gatttggata ttatcaaaaa agcaggggct tggtattctt acaaagatga
    17881 aaaaattggg caaggttctg agaatgctaa gaaatacttg gcagagcacc cagaaatctt
    17941 tgatgaaatt gataagcaag tccgttctaa atttggcttg attgatggag aagaagtttc
    18001 agaacaagat actgaaaaca aaaaagatga gccaaagaaa gaagaagcag tgaatgaaga
    18061 agttccgctt gacttaggcg atgaacttga aatcgaaatt gaagaataag ctgttaaagc
    18121 agtggagaaa tccgctactt tttcgatttt tgattcaagt ttttagatta tatatagtag
    18181 attgaaataa gatatgaaca actttattag gaaagtcaaa ttaatttcta gaaatgtttt
    18241 agcagctaca gcgtactatt ccaaactcaa ccaactataa tagatcgaaa ctagaatagt
    18301 acacatctac ttctaaaaca ttgttaaaaa tcgatttgac tgtccttatt tcattccgct
    18361 atatataagt ttgctgtttc ttgtcgctcc tctggaaagc tgatataata gctttatgaa
    18421 taaaaaacga acagtggacc tgatacatgg tccgattctt ccctcgctct taagcttcac
    18481 ctttccaatc ttgttatcaa atatttttca acagctctat aacactgctg atgtcttgat
    18541 tgttggacga tttcttggtc aagaatcctt ggctgcagta ggagcgacga cagcgatttt
    18601 tgatctgatt gtaggtttta cacttggtgt tggcaatggc atggggattg tcattgctcg
    18661 ttattatggg gctcggaatt tcactaaaat caaggaagca gtagcagcca cctggatttt
    18721 aggtgctctt ttgagcattc tagttatgtt gctgggcttt cttggcttgt atcctctctt
    18781 gcaatactta gatactcctg cagaaattct tcctcaatct tatcaatata tttctatgat
    18841 tgtgacctgt gtaggtgtca gctttgctta taatcttttt gcaggcttgt tgcggtatat
    18901 tggtgacagt ctagcagccc tgggatttct gattttctct gccttggtta atgtggttct
    18961 ggatctctat tttattacgc aattgcatct gggagttcaa tccgcaggac ttgctaccat
    19021 tatttcgcaa ggtttatcag cggttctctg cttttattat attcgtaaaa gtgtgccaga
    19081 actcttgcca cagtttaaac atttcaaatg ggacaaaagc ttgtacgcgg atctcttgga
    19141 gcaaggtttg gctatgggct tgatgagttc aattgtatct atcggcagtg tgattttaca
    19201 gttttctgtt aatacatttg gtgcagtgat tattagtgcc cagacggcag ctcgacgcat
    19261 tatgaccttt gcccttcttc ctatgaccgc tatttctgca tcaatgacga cctttgcttc
    19321 tcagaatcta ggagctaagc gacctgaccg cattgttcaa ggtcttcgaa tcggcagtcg
    19381 tttaagtata tcctgggcag tttttgtttg tattttcctc ttttttgcca gtccagcctt
    19441 ggtttccttc ttggctagtt cgacagatgg ttacttgata gaaaatggaa gtctctatct
    19501 gcaaatcagt tcagcctttt atcccatttt gagcctcttg ttgatttatc gcaattgctt
    19561 gcagggcttg gggcagaaga tccttcctct agtttctagc tttattgaac taatcggaaa
    19621 aatcgttttt gtggttttga ttattccttg ggcaggatat aagggtgtta tcctttgtga
    19681 acctcttatc tgggttgcca tgacagttca actgtacttc tcactattcc gtcatccctt
    19741 gataaaagaa ggaaaggcaa ttttggcaac caaagtgcaa tcctagttgg atttactgaa
    19801 taaaatccat ttcctctagt gaacatcgaa aaaacttgtg ttctcttctt cagtttggtg
    19861 ttgaaaatag tttaacagac ttttgacttc ttttatatga tataataaag tatagtattt
    19921 atgaaaagga catatagaga ctgtaaaaat atacttttga aaagcttttt agtctggggt
    19981 gttattgtag atagaatgca gaccttgtca gtcctattta cagtgtcaaa atagtgcgtt
    20041 ttgaggttct atctacaagc ctaatcgtga ctaagattgt cttctttgta aggtagaaat
    20101 aaaggagttt ctggttctgg attgtaaaaa atgagttgtt ttaattgata aggagtagaa
    20161 tatggaaatt aatgtgagta aattaagaac agatttgcct caagtcggcg tgcaaccata
    20221 taggcaagta cacgcacact caactgggaa tccgcattca accgtacaga atgaagcgga
    20281 ttatcactgg cggaaagacc cagaattagg ttttttctcg cacattgttg ggaacggttg
    20341 catcatgcag gtaggacctg ttgataatgg tgcctgggac gttgggggcg gttggaatgc
    20401 tgagacctat gcagcggttg aactgattga aagccattca actaaagaag agttcatgac
    20461 ggactaccgt ctttatatcg aactcttacg caatctagca gatgaagcag gtttgccgaa
    20521 aacgcttgat acagggagtt tagctggaat taaaacgcac gagtattgca cgaataacca
    20581 accaaacaac cactcagacc atgtggatcc atacccttac ttggcaaaat ggggcattag
    20641 ccgtgagcag tttaagtatg atattgagaa cggcttgacg attgaaacag gctggcagaa
    20701 gaatgacact ggctactggt acgtacattc agacggctct tatccaaaag acaagtttga
    20761 gaaaatcaat ggcacttggt actactttga cagttcaggc tatatgcttg cagaccgctg
    20821 gaggaagcac acagacggca actggtactg gttcgacaac tcaggtgaaa tggctacagg
    20881 ctggaagaaa atcgctgata agtggtacta tttcaacgaa gaaggtgcca tgaagacagg
    20941 ctgggtcaag tacaaggaca cttggtacta cttagacgct aaagaaggcg ccatggtatc
    21001 aaacgccttt atccagtcag cggacggaac aggctggtac tacctcaaac cagacggaac
    21061 actggcagac aagccagaat tcacagtaga gccagatggc ttgattacag taaaataata
    21121 atggaatgtc tttcaaatca gaacagcgca tattattagg tcttgaaaaa gcttaatagt
    21181 atgcgttttc ttgtggagat atttccttca atttttgcta ctatattaaa caaaaatcaa
    21241 aaagcaaact agaaagttat gctcaaataa aatctaaatt tgacaatgta aaccgagtcg
    21301 gatagcttta agtactgttt tgaggttgaa gatacgattt ttgataggaa ctcatcaaat
    21361 aggtttaata tcatcaattt tagattttta agtagcatca ataaattgct tccttgtttt
    21421 gtcataattt ttttatttaa aaaattatga caagagtgtg ctattctttt tatgagaggt
    21481 gtatgaatat gataaatgta tgtgataaat gtatgtgatg ttggaaaaag aataaaagaa
    21541 cttagaatat cttcaaatct tactcaagat aagattgctg agtatttgtc tttgaatcaa
    21601 agcatgattg ccaaaatgga aaaaggtgaa aggaatatca cgaatggatt taagtaataa
    21661 agctccaaat cttagaaaaa agttgggagc tgatggtgaa tcgccgatag atatttttaa
    21721 attggtacaa aagatagaaa atttgacgct ggtattttat ggactcggaa agaatattag
    21781 cggagtctgt tataaaggaa ctcagttcag tctcattgca gtcaattcag acatgtcatt
    21841 aggaaggtaa agattttctt tagcacatga actgtatcat ctttattatg atgaggtgaa
    21901 gaagagttca gtcagtctta tcttgattgg tgaaggagat gaaactgaaa gaaaagcgga
    21961 tcagtttgct tcttattttt taattttccc atcttcactg tataggatgg ttgaggaaat
    22021 cagagaaaat gccaatagaa ctcatcttga agtagaagat attataaaat tgggtcagtt
    22081 ttatggtatc agtcataaag ctatgttata tagattgagg aatgatggat accttgatgc
    22141 agaagaaatt aaaaatatgg atattagtgt tatagagaca gcttcaagat taggctatga
    22201 tacaagttta tatcgtcctt tgtcagaaag taaaaagaaa tgttattagg ataatatatt
    22261 aatctaactg aacaactttt agaaaataac agaatttcgc aagggaagta tgaggaactg
    22321 ttactagatg ctttcagata tgatattgta tatgggctag atgaagaggg gggagttgtc
    22381 gtttgactag tcgtgtattt attgatgcag attgtatttc agtattttta tgggttggca
    22441 ctgaacatct tttagaaaag ctctatttgg gtaaaattgt tattccacaa gaggtgtatg
    22501 atgaaatcaa tatacctaca attccccatt taaaatctag gatagatcag ttggtagcta
    22561 agggttcagc tgagattgtg agcatagaca ttggaactga agaatacgca ttatatagag
    22621 atttaacaag aaatcatgat agtaacaaga ttattggtaa gggagaagcg gcttctattt
    22681 ccttagcgaa aaagcataat gggatattag gaagtaataa cctaagagat gttaaatcat
    22741 atgtaaaaga attttcttta gaatatatga caacaggaga tatactggtt gaagcgttta
    22801 aagcgtaatt tattactgaa caagagggca atcatatctg gaataatatg cttaaaaaga
    22861 gaaggaaaat tggtgcaaat tcattttcag actatcttcg tggaagtatt catcaaaata
    22921 gacaaaaata aatttggata aatcgaactc actattcagg aggcatatga gcaattcgaa
    22981 aaagaaaagt gtcaaattga gcctatagga gtagaagtga aatagtaagt cctgcatagt
    23041 ggatgagaga aaagttctcc ttgaagtttt cctgaactat cagtcgcatg tcaaacgata
    23101 tgtagggtaa tgtgagaggg gatagcgagt agtttttggt tattttatca aaaaacttat
    23161 attttattat accgaatgat aaaatataat aaaaatgata gaataaggaa aaaacatgaa
    23221 tgtcaaaaag ataatgtcaa tttttcaatc cttttatgtt gatgtcagta ttgaggaact
    23281 gactttacca atcagttttg taaaaaagtt tgagtatact caaatgactt ttcataagga
    23341 atcattttta ttgattaaag aaaagagaag ggggagtttg agttcatttg ttactcaggc
    23401 tcgcactatg ggtgataaag ccaatatgga tgttgttttg gtgttttcga agttatcaga
    23461 cggtgaaaaa aaagcaatta cttcaagcta gagttccgtt tgtagacttt aagggaaacc
    23521 tcttcttccc tacattggga ctagtactga atgcgaatga tactgaagtc cctaaggaat
    23581 taatacctag cgaacaatta acgtggattg cctttttatt gacaaaaggt caaaaagtag
    23641 tagatgttga tttgctttca caagtcactg gacttccaaa ctcaacaatt tataggtgtt
    23701 tgaggacttt taaagcttta tatttgttaa acaagcaaaa taagctttac acatatacgg
    23761 tgtcaaagaa agaattattc ttaaaatccg tgtcatgttt atttaatccc atcaaaaaac
    23821 ggattttatt gccagatggc gatataaagc agataaaatc tgtttctaac cttctatatg
    23881 gtggtgctta tgctttgtcg cattcaactt ttttagctga aacggatgaa aatattagct
    23941 atgtcatatg gcagagaaaa ttcaatcagt tacccttgcc actttctcag catattttaa
    24001 aaggaaagat gctagagata tggaaatatc gtccttttgt atctgagttt tggaatgatt
    24061 ttaaaaataa tcatgataaa caatttgtag atccgatttc tctttatttg accttaaaag
    24121 atgatgatga cccacgtata gaggaagaga gtgaagcact agaaaatatg atattacagt
    24181 atctgggaga agatgatgcc agctaatacg aaagttattt ttcaagaaac gtttgcggat
    24241 tttcagaact attatgttct gattggggga actgctacct ctatcgtatt ggattcgcaa
    24301 ggatttaaaa gtcgcacaac aaaagattat gatatggtca tcattgatga agtaaaaaat
    24361 aaggaatttt atactacctt gaatcatttt ttagaattgg gagagtatca aggaagtcag
    24421 aaagatgaga aagcgcagct ttttcgattt acaacaacta atcctgagtt tccttctatg
    24481 attgaactat ttagtatctt accagaatat tcattaaaga aggacggtcg agaaattccc
    24541 ttacattttg accaagatgc tagtttatca gccttattat tggatgaaga ttattataat
    24601 atattggtgc atgaaaaaga aaccattcag gggtattcgg tattgagtaa ttgtggtcta
    24661 tactcttcga aaatctcttc aaaccacgtc agcttccatc tacaacctca aaacagtgtt
//
LOCUS       DBERAE010000031        24688 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.31, whole genome shotgun sequence.
ACCESSION   DBERAE010000031 DBERAE010000000
VERSION     DBERAE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.31"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..705)
                     /locus_tag="ACL70N_001465"
     CDS             complement(<1..705)
                     /locus_tag="ACL70N_001465"
                     /inference="COORDINATES: protein motif:HMM:NF013539.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS0590248.1"
                     /translation="MREKIADYILVRDSEIVYETSSEIVSKVKVGEGTLNRFCKKIGY
                     SGFQELKLKMTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIELAIKLI
                     REANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDLIIAFS
                     LSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGGSLMAK
                     ASQLFIIDVICTRLSLI"
     gene            910..1479
                     /locus_tag="ACL70N_001466"
     CDS             910..1479
                     /locus_tag="ACL70N_001466"
                     /inference="COORDINATES: protein motif:HMM:NF016726.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGS0590249.1"
                     /translation="MLNLLYVASVVTVIAIGSGESALIATLIKIVRHEESYPYRDFAN
                     SFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRHIGVIYIILHLIAT
                     TFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLLFFILQNQLLVWIT
                     LMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            complement(1714..3065)
                     /locus_tag="ACL70N_001467"
     CDS             complement(join(1714..2624,2624..3065))
                     /locus_tag="ACL70N_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0590250.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(3158..4489)
                     /locus_tag="ACL70N_001468"
     CDS             complement(3158..4489)
                     /locus_tag="ACL70N_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGS0590251.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLTDKE
                     ELVELLTRCAQNYQLRYEEFDYLASLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(4511..6022)
                     /locus_tag="ACL70N_001469"
     CDS             complement(4511..6022)
                     /locus_tag="ACL70N_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGS0590252.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(6231..7178)
                     /gene="arcC"
                     /locus_tag="ACL70N_001470"
     CDS             complement(6231..7178)
                     /gene="arcC"
                     /locus_tag="ACL70N_001470"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGS0590253.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(7343..8359)
                     /gene="argF"
                     /locus_tag="ACL70N_001471"
     CDS             complement(7343..8359)
                     /gene="argF"
                     /locus_tag="ACL70N_001471"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGS0590254.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(8417..9646)
                     /gene="arcA"
                     /locus_tag="ACL70N_001472"
     CDS             complement(8417..9646)
                     /gene="arcA"
                     /locus_tag="ACL70N_001472"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGS0590255.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            10402..12081
                     /locus_tag="ACL70N_001473"
     CDS             10402..12081
                     /locus_tag="ACL70N_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS0590256.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(12121..14205)
                     /locus_tag="ACL70N_001474"
     CDS             complement(12121..14205)
                     /locus_tag="ACL70N_001474"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGS0590257.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            14376..15656
                     /locus_tag="ACL70N_001475"
     CDS             14376..15656
                     /locus_tag="ACL70N_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGS0590258.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            15747..18392
                     /locus_tag="ACL70N_001476"
     CDS             15747..18392
                     /locus_tag="ACL70N_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGS0590259.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKVLHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            18476..19345
                     /locus_tag="ACL70N_001477"
     CDS             18476..19345
                     /locus_tag="ACL70N_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0590260.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            19339..21219
                     /locus_tag="ACL70N_001478"
     CDS             19339..21219
                     /locus_tag="ACL70N_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGS0590261.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVTIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            21609..21935
                     /locus_tag="ACL70N_001479"
     CDS             21609..21935
                     /locus_tag="ACL70N_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590262.1"
                     /translation="MILWSFDFANDHAHAFFMDNVEWSHADSYFFSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(21987..22829)
                     /locus_tag="ACL70N_001480"
                     /pseudo
     CDS             complement(21987..22829)
                     /locus_tag="ACL70N_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(22818..22967)
                     /locus_tag="ACL70N_001481"
                     /pseudo
     CDS             complement(22818..22967)
                     /locus_tag="ACL70N_001481"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            23302..>24688
                     /gene="pcpA"
                     /locus_tag="ACL70N_001482"
     CDS             23302..>24688
                     /gene="pcpA"
                     /locus_tag="ACL70N_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGS0590263.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT         7257 a         4895 c         5144 g         7392 t
ORIGIN      
        1 tattaaagag agtctagtgc atattacatc aattatgaat agttgagaag ccttagccat
       61 taaactacca ccctctaaat aagattcttt ttttgatgtc aaaagaacgc agtcagataa
      121 ttttgctata tttctggacg aataatttgt tattgaaata attttaacat tttttctttt
      181 tgcgtttaat aaagtttcct caacttcttt tgtggaacca gataaactaa acgctattat
      241 caaatcatta tctttcaata acgcagtatg catgagttga aaatgggtat caattaccgt
      301 cttacttatt attccaattc ttaacaaact actctcaaat tctctagccg catttccact
      361 agaacccaca ccaatcatta aaatctggtt tgcttctctt attaatttta tagctaattc
      421 tatttgtcta ccatcaatta attttcttgt actttccaca atagataaat aattattttt
      481 tatttcatca ataaatgtgt cactactcat tttttgagat tctaactcta atatatcttt
      541 cgtcattttt aattttagtt cctgaaaacc agagtatcca atctttttgc aaaatcgatt
      601 aagagttccc tctccaactt ttactttact aacaatttct gaagacgttt cataaactat
      661 ttcactatct ctaactaaaa tatagtcagc aattttttct ctgatttagt aagattatcg
      721 tattcataat gaattctttc tttatatttt ttggatttat tcataataat tttttccttt
      781 cctcatagtt atattctttc ttaatgtatt caaagttgat gaaactcaaa tgatgtgata
      841 ttataagtat aaaaacagca ggagttaaag atgcagataa aatttattga taaagtttca
      901 aatcttataa tgttaaatct actctatgta gcgtcagtag taacagttat tgctatcgga
      961 tcaggtgaaa gtgccctaat agcaactcta ataaaaattg tacgacacga ggaatcctat
     1021 ccctatagag acttcgcaaa cagttttttt aaagattatt ggaaaaattt aggagcagca
     1081 ttaatatcta atttaccaat tttaatctta ttattcagtt tgttcttcct accctacata
     1141 ccattaccta tatatatcat ttctatctta cgacatattg gagtaatata tatcatactt
     1201 catttaatag caacaacatt tctaattcct ttaatcggta gatataataa cactttaaaa
     1261 aattctctac acaattcaat catgttagcc tataaacatt tttttattgc cgttcttatt
     1321 agaattattg aaattatccc agttctactc ttctttatat tacagaatca attactagtt
     1381 tggataactt taatgatttt tatacttccc tcaataacaa aatatgctaa tgcattttta
     1441 tataacttta tattctcgaa gtatgaaaaa ttaaactaga gaacatctca tagccttgca
     1501 tcttgatttt ataaaaattt ttaactaatt tcaacgataa aataatttta atttcaaaaa
     1561 actatatgac ctgactattt tttaaattat tcataatatt tttagtcttt agtaaatttt
     1621 ctaaaaataa aacaagaaca gattttttat tataaaacgc ataagatcat ggtatttaat
     1681 actgtactga ccccaaaaaa ttagacaaat aatttatcca aaggatttag ttctgtactg
     1741 cacagaacta agtcctttta gttttacctt aattcgtttg ttgttgtagt aatcaatgta
     1801 gtccacaata gcttgttcaa ggttttctaa agatctaaag ttcttctcat agccataaaa
     1861 catttcggat tttaaaatgc caaagaaaga ttccatcatg ccgttgtctg ggctgttgcc
     1921 cttgcgtgac atggatgctt gaatttcctt actctctagg aaccgatgat aagaatcgtg
     1981 ttggtattgc cagccttggt cactatggag aatcgtattc tcatagtatt tctctgtaaa
     2041 ggcctgttct aacatactct tcacttgttc taagtttggc gaagtagaaa gatgataagc
     2101 aatgatttca ctgttaaaac catctaaaac tggtgataaa tagagtttct gtgtgctatt
     2161 tggaatggca aactctgtca catctgtata gcacttttcc attggcctcg atgcttcgaa
     2221 ctggcgttga atgagattct ctgctttctt gccaatctct ccttggtagg aagaatactt
     2281 ccgtttacgg cgaattcgag ccgttaaacc aagaattctc atcaaccgtt gaactttctt
     2341 atgattgacc acaaaaccac gattccttag ttctaaatgg attcgacgat agccatagtt
     2401 gcctttatgt tcattatcaa tgccctgaat ttcggtttta atctctttat ctttatcaac
     2461 cccatccagt tgtttcaact gataatagta agtcgagcga gctaaacgtg ctgtttcaag
     2521 aagaaaatct agtcgaaatc ctcctgaaac catttctcta actgtctctg cctttctcgc
     2581 tctagggctt cgtccctttc ctctaactct tttaactttt ttaggtaggc cacctcagtc
     2641 cgtaagcgtt cattctcctc ctggagtcgt tctagttctg tcatttcttc ccaagtcttc
     2701 ttccgtttac gtcccatttt agctggtctc cctcttgttt tctcaacaat agtatacccg
     2761 tttttcttgt attgtgccgg ccaaaatgaa agcattcctt ggtttgggag ggcataatca
     2821 agactaatac ttctttgtga acaaccttcc agtaaggctt tatccatcat ttcttgtttc
     2881 aatttagaag aatagtgacg attcttccct tttttaacga tttctatgcc ataacggtca
     2941 attaatttca ccatgtactt tagaccagaa acatccacac caaatctttt tgaaagctgt
     3001 ttgaagcttt gtccttgctt tcttagttca tagatctgaa ctttatcttc ataactcaat
     3061 ttcataataa aacaccccaa aagttagatt tattctgtct aacttttggg gtgcagttca
     3121 ttttgcggga ttttttttgg tagaaacagt tgcctgatta agttgcaagt cgatagacgg
     3181 cttcggcata aatatccata gcacggtaca aatcttctag aacggcacat tcatttgcct
     3241 gatgttctgt ctgcttcgct cctgggaata aggcgccgaa ggctacacaa tttggcatgg
     3301 tgcgagcaaa agtggcacca ccggatgaaa tagcaggact gttatcgcca gtcttttctt
     3361 ggtagatttg catcagtgtg ctaacgagtt tactgtcttt tgcgacgtat agagacgcta
     3421 gatagtcaaa ctcttcgtag cggagttggt agttttgtgc acatcttgta agcaactcta
     3481 ctagttcttc cttatcagtt aagacaggag tccgaatgtc aatacggatt tcagaacgtt
     3541 catgattgat catgagacct gcgacattaa aggataggtg accagaaggt tcatctgcta
     3601 tatcaccaaa gatttgtctt cctgtgccgt cttgacctgc ttgtgttgca agaaagctga
     3661 gagcagggtg ttcttggaga ggagcaagaa tggtagctag tcggatgaca gcattgatac
     3721 cttgactagc atccttagca tgctttggca ctccgagaac cgttacggtt tgttcagtgg
     3781 attggtaatc ataaccagct tctttgagat cgttacaaac ctgttcatag aggggacctt
     3841 ggtagttggc cttgtctggt acaacgttaa aggcgcctcc tacttcaagc tctagttgat
     3901 ccgatccagg gccatgaagt ttgacctgta gaagcccttt ttcagcatag gtcagaggaa
     3961 aagatgagtc aggtgcaaag cccatgctgg cctgttcttc gatggtattg tagcgtgcca
     4021 tgcagcgcca gagggtttcc tcatcggtac caaagataaa gcgtacgcgc tttttgaact
     4081 gaataccttg gtccagcaag ctttttactg catagagagc tgcgagcgaa gggcctttat
     4141 catcttggac accacgtccg aatacccagc cgtctttgat agttgcttca aatggcggtg
     4201 tctgccaatc tgcttcatca cctgatggaa caacatccaa atgacagaga atggccagaa
     4261 gctctgctcc ctgaccgatt tctgcatatc cgtaataacc tttagggtca agataggtag
     4321 tgaaacctat gtctcgacaa atctctaaag ttttttctag gacatcttgg attgcttgtc
     4381 caaaaggtgt tccattttct ccttcattga gtactgaagg ataggaaatc aaggttttta
     4441 atgatataag aaattcatct ttaacttgat ttgttatatc tattttcatg gaatcacctc
     4501 actcactatt ttataggaat ggaaggaagg ttccaaggag aagaagggcg atggtcacta
     4561 caataatagc gactacgagt ttgcccatga atttccacca agtaccaatg ttgatacgtc
     4621 caagtgcaag agctcccatc acaataccag atgttggtgc aatcaagttc aagacacctg
     4681 aagcagattg gtaagcagtg ataatcaagc taggacggac atttacaaat tctccaagtg
     4741 gagccatgat acccatagtt gcgctggcaa gaccagatga agatgggatc aagaatgaca
     4801 taggtagata gaagatataa gttacaacga taaagacttg tgaagataga ccgctcaagc
     4861 cttctttacc ccagttgagg attgtatcgg taatcatacc gtcgttcatg ataacttgaa
     4921 taccacgagc aatcgctacg atcaaggcaa cactgagcaa gtcagcagca ccattcatga
     4981 aggaagagat aatcttatct tctttaagac cataaataac accaatcagg atacccataa
     5041 aggcaaagag cattgcgcct tctgggaagt accaagtacc tagtgcagaa gtagatgaac
     5101 cgacaatatt accaataact ggaagaccag tcaaccaagc attaaagtca tcaaaaatgg
     5161 taacgccaag gtctgtccat ggaatgaagc tcaataccat caagatgaat gtcaacacaa
     5221 ataagaagag aactgatttt tgtttgctgc taagtgtaga ttctacagat gaagattctt
     5281 ctacgttaaa gtgtttcaaa tcttctttgc gagtactata aaccagtgac ttagtcggat
     5341 ctttttgaat cttatccgca taacggtaaa caaaccaagt actaagagca gtcaaggtaa
     5401 cccagaagat cagacgaagt acgataccgt cccctgtacc aactcccgca gtcgctgaag
     5461 caatacctgt cgcaaatgga ttcagagtag atgctaaaca gccgatttga gaaccgagca
     5521 aaataattgc aacaccagtc aggctatcaa aaccaacggc catcataact ggcacaagga
     5581 gtggatagaa ggccattgtt tcttcaccca taccataagt tgtaccaccg agggcaaaca
     5641 aaggcatcag taccaaaatt aacatttttt cgcggccctt atacttcttc acgatagagg
     5701 caatccctac gtcaagagca ccagttttgt tgacaatgcc aaggaaacca ccaaccataa
     5761 ggatgaagaa ggctacatca atcgctgcgc tcgtttcttt aatgagcgaa ccttcctctg
     5821 gatgagtacc tagcatagcc cgaatcggtg ccatgaggac atcccaaatc ccttgtggat
     5881 tttgaggctg agtctcgtaa ataccttcta taaaggcccc cgcagggata aaccaagtta
     5941 gcactgccat aatagcaatg attatcaata atacggtgta agatgaaggc atcttaaacc
     6001 cttttttagc tttttcactc atttgttttt cctcctgatg tctaacaaag tgtaaaaaac
     6061 caactacttt cttaaataaa cattcaagaa aacgctttct atttatattt gttttaccat
     6121 attaaagtct aaaactagta tcttttgaaa tattgtacat gttttcaaga ataatttcta
     6181 atttgatata aagatactag aaatagaata catcttatta gtaaaacaac ttatcctttt
     6241 tcaataattg ttccgctttc agattcaatc aaggcgccta gattttcaag ggaagtaata
     6301 actgcttttc cttctggacg accattgaca aaagcgatag ctgcttctac ttttggaagc
     6361 atgctacctg gtgcaaactg atcttgtttg atatattctt ccagctgggc aacattcaca
     6421 tgttccaatt tttcctggtt tggcttgttg tagttaacaa atacataatc tacacctgtc
     6481 aaaacgatga agaggtctgc atcaaccaat tctgccaaac gttgggaagc gaagtcttta
     6541 tcaataaccg cttcgacacc agtcaaatgt ccattgtttt ctttgacgac gggaataccg
     6601 ccaccacctg cagctacgac gacttgacca ttatttaaaa gagtacggat ggtttcaatt
     6661 tctttgatgt caacaggttt tggtgaggca acgaccttac gccagccacg gccagcatct
     6721 tccttgaaag tcgctccgct cttttcggct tctgcttttg cttcttcttc tgaatagaaa
     6781 ggaccgattg gtttactcaa gttaacaaaa gctggatcat ttttatctac gacaacttgc
     6841 gttacaacag aggcaacatt tttttcgatg ccttcatcca agagagcatt ttgcaaagca
     6901 tttttcaacc agaaaccgat gctaccttct gtcatagcga caagtgagtc gagtgggaag
     6961 gcagggttct tttcagagtc tgatgccaaa tgttggagca agagattccc aacttgaggt
     7021 ccattaccgt gagtgataat cagatcatct ccatttttaa tcaattttac aagatgctta
     7081 gctgtttcaa ctaaagcttc ttgttgagcc tttgctgatg ggtcagaaga aagaatcgca
     7141 tttcctccca aagctactac aattttacga tttgccataa attctccttt atcacactca
     7201 atagaatgcg tttagatttc aatttaatga tttttcacat attttataag aaataataga
     7261 ttaccattat ataaaagagg accggactaa agctattagt cgcagccctc atagctgttg
     7321 gtagacggtt tattatctaa aattatactt taggaatata aaggttacca agtgtagcag
     7381 ccataacagc tttgatagtg tgcatacggt tttctgcttg atcgaagtgg cgagcgtact
     7441 tgctgcggaa gacttcgtct gttacttcca tttcttctac accaaatttt tcagcaacgt
     7501 ctttaccata aacagtgtga gtatcgtgga atgctggcaa gcagtgtagg aagatcaagt
     7561 tttcattgcc tgctttttta actaagtcca tattgacttg gtaaggttta agaagagcta
     7621 cacgttctgc gaatttgtct tcttcaccca ttgataccca aacgtctgtg taaagaacgt
     7681 ctgcatcttt aactgcttca tcagcatctt cagtgatgag aacatgtgcg ccactttctt
     7741 tagcaaatcc ttctgctaat tcaacgattt ctttttctgg gaagagttct tttggtgaga
     7801 agatgtgaac attgacacca aggatagcac ctgttacgag caagctgttg gcaacgttgt
     7861 tacgtccatc accacagtat accaatgtca agccttccaa gcgaccgaag ttttcttgaa
     7921 cagtcaagta gtcagcgagc atttgagttg ggtgccattc gtcagttaga ccgttccata
     7981 ctggaacgcc tgagaattct gccaattctt caaccatacg ttggctgaat ccgcggaatt
     8041 caatcccgtc aaacatacgt cccaatactt tagcagtatc ttcagtagat tcttttttac
     8101 ccaactgaat atcatttgct ccgaggtatt ctgggtgagc accaaggtcg atagccgcag
     8161 ttgtaaaggc tgcacgagta cgagtagatg ttttttcaaa taggagagcg atattcttgc
     8221 cagcaaggta gtggtgttga atattgcgtt ttttcaaatc tttcaagtga gctgaaagac
     8281 caataaggta ttctaactct gcacgggtaa agtctttttc tgctaagaag ctgcgtcctt
     8341 ggaatactga atttgtcatt ttattatttc ctctttctat tttttacatt ttctattgac
     8401 gaatgccgaa cagcgattac acttcttcac gttcaaatgg catagacata caacgaggtc
     8461 caccacggcc ccgaaccaat tcacttccgc gaatcttaat caagcgaagc ccgtattctt
     8521 ccaaaatctt attggtcacg gtattgcggt cataaacaac taccacacca ggtgcgatgg
     8581 tcaaagtgtt agaaccgtcg ttccattgtt cacgcgcagc tgctacgata ttgccaccac
     8641 cgcaacgaat caaatgaact ttttctacac caaggttttg agcaagaagt tcagctaagt
     8701 cacctttctc ttcaacgatt ttaagttttt cgttttcgta agtaactgag taaacgtgaa
     8761 ggtcgccttc gatttctggg tgaatagtga acttgtcata gtctaccata gtgaagacag
     8821 tatccaagtg catgaattta cggttgttag caaattcaaa ggccaaaact ttcttgaagc
     8881 caacattttt cttgaagatg ttgaccaaaa gtttttcgat agaagctgcg tctgtacgtt
     8941 gagagatacc tactgcaagg acgtctttag aaagaactaa ctcgtctcca ccttcgatac
     9001 gcgtatcttc ttcacggttg tagaccaaat ccacttttcc gccatagatt gggtggtatt
     9061 tgaagatata cttaccgtag agtgtttcac ggttacgagt gtctgcaaac atgtggttaa
     9121 gcgatacggc gtttccaatt gttgcaaatg ggtcgcgagt gaaatagagg tttggcatcg
     9181 ggtcaattgc aaatggataa tctgattcaa ctaagtcagt tagatcttta gcttcgtcag
     9241 gaatttctgg caattcaact ttttgaatcc cagccattgt tttttcaacc aattcttggt
     9301 tgtccttgat gccgtgaagc aattcacgaa tagcaacctt ggtttgacga tcacggatgt
     9361 tggcttcgtc taagtattcc tcgataaatt gatcgcggat ttctggagag gtcaatgatt
     9421 cagcagcgag ttgttctagg tagagaacct caattccttc atcgcgaaga gcttgggcaa
     9481 atgcatcatg ttctttttga gcatcttcca agaaaggaat atcatcaaaa agaagccttt
     9541 caagatagtc cggcaacaag ttttctaact ccttgcctgg acggtgcaac ataacttttt
     9601 tcagtttccc aatttctgag aagacctgaa ttggatgtga agacatgtat tttcctcctt
     9661 aaaaattttg acttggcacc attttgggta ccgcttacat gtatgttata acgcaattcc
     9721 taggtaatgt caatggctat aatttctcgg aaaataatat aaattatgat gtttagcaca
     9781 attttatgtt attatacata acataggata gaatacatag atacaaatgc ataaacttct
     9841 attaaagagg atataaaatt tttttaaaaa atttttcaaa aaatacacaa ataaccaaaa
     9901 agtgtccaat tatcatctgg ttatcacttg gatctgtata aagagaaatg tttgtgtgaa
     9961 aggataaaaa gatgcaacat tcttttgaag atagattttg gagaagcatt tcttgttcaa
    10021 ttgtacaaat tatagaatct tttctgagta tttaggaaga gataattatc ttattgaccc
    10081 tctttttatt ttttgttata gtcgacgaga tgatagttta gaataatcac ttattcacaa
    10141 tctgtggaaa agtctggaga gtgaatggtc ttcacacaat gacctgaaag aagcctgaga
    10201 ataattatgg agagtagcat tctgagaggt gttagcagaa ccatatgaca gagctgtttg
    10261 aagagggaat attgaggaga aaaatcctga gcctaccagt tggagttgga aagagctggc
    10321 ggttagatca ttttttatta tccacaacct gtggataacc ttgtgaacaa gagaagttgc
    10381 taaagaagga gatatataac gatgaagaaa atcaaaccgc atggaccgtt accaagtcag
    10441 actcagctag cttatctggg agatgaacta gcagctttta tccacttcgg tcctaatacc
    10501 ttttatgacc aagaatgggg gactggacag gaggatcctg agcgctttaa cccgagtcag
    10561 ttggatgcgc gtgagtgggt tcgtgtgctc aaggaaacgg gcttcaaaaa gttgattttg
    10621 gtggtcaagc accacgatgg ctttgtcctt tatccgacag ctcacacaga ttattcggtt
    10681 aaggtcagtc cttggaggag aggaaagggc gacttgctcc ttgaagtatc ccaagctgcc
    10741 acagagtttg atatggatat gggggtctac ctgtcaccgt gggatgccca tagtcccctc
    10801 tatcatgtgg accgagaagc ggactacaat gcctattatc tggctcagct gaaggaaatc
    10861 ttatcaaatc ctgcctatgg aaatggaggg aaatttgctg aggtttggat ggatggtgcc
    10921 agaggagagg gcgcgcaaaa ggttaattat gaatttgaaa aatggtttga aaccattcgt
    10981 gacctgcagg gcaattgctt gattttttca acagaaggca ccagtatccg atggattggc
    11041 aatgaacgag ggtatgcagg tgatccactg tggcaaaagg tgaatcctga taaactagga
    11101 acagaagcag agctggacta tcttcagcac ggggatccct cgggcacgat tttttcaatc
    11161 ggagaggcag atgtttccat ccgtccaggc tggttctacc atgaggatca ggatcctaag
    11221 tctctcgagg agttggtcga aatctacttt cactcagtag ggcgaggaac tccactcttg
    11281 cttaatattc cgccgaatca agctgggctc tttgatgcaa aggatattga acgactttat
    11341 gaatttgcga cctatcgcaa tgagctctat aaagaagatt tggctctggg agctgaggta
    11401 tctggtccag ctctttccgc agactttgct tgtcgccatt tgacagacgg ccttgagacc
    11461 agctcttggg caagcgatgc agacttgccc atccagttag aactcgactt aggttctcct
    11521 aaaacttttg atgtaattga gttgagagaa gatttgaagt taggccaacg tatttctgct
    11581 ttccatgtgc aagtagaggt ggatggtgtc tggcaggaat ttggcagggg cttcacagtt
    11641 ggtcataagc gcctcttgcg aggagcagtt gttgaagcac agaagatacg tgtagtcatt
    11701 acagaatcac aggctttgcc tttgttgacc aagatttcac tctataaaac tccgaggtta
    11761 tcacaaacag tagctgttca ggggctagca tttgcagaaa aaagcctagc tgtggcaaag
    11821 ggagagactc ttcattttag gattgaacgt agtgaaagta gctcctcttt agaggctaag
    11881 atttcgattc aaccggggac aggtgtccat ggtgtcgcct atcaggatga gattcaagtc
    11941 cttcaattcc aagcagggga aagcaaaaaa gatttgcatc taccaaccct gtatttcgca
    12001 ggagataaaa ccttggattt ctatctgaac ctaacggtgg atggtcagct tgtggatcaa
    12061 cttcaagtcc aagtttcata aaagaagaac ctttgcgcga tgcaaaggtt cttttggtta
    12121 ttagtgattt ggtagccagc tgagggtgaa agttagttgt tcagctttta ggaggtcttg
    12181 gtgttgaata gttgatacga gtgttttgtc cagtcggcat tctttgacaa agttaaaatg
    12241 gctgtggttt tgctcagtat gaatatctag ccatttattt tctttagcta ggtagactcg
    12301 tagatggtca aagagaggaa ttccgagatc atagcttggt tttcctggac aggttggata
    12361 aaatccgaga gctgaccaga tgtaccaagc agagagacta ccattgtctt catctccagg
    12421 ataggcttcc caacttgggt gaaaagcttt ctgacggagc gtcttgataa gaagggcagt
    12481 gtagtcaggg taatcgctgt agcggaagag ataaggaatg tggaaactag gctggttgga
    12541 aatggctatt tgtccaaaag gagcagtagc catctcgctc atttcgtgaa tttcgtaacc
    12601 atagcctgtt gtttcaaaga ggggagcatc ttgacaggct ttcaaaagat agttgctaaa
    12661 ggtttctttt ccacccatca gttggattaa gccagggatg tcgtggagaa cgcctaaagt
    12721 agcttgaatg gcagagcatt cagcgtagtc tcgcccccaa ctataaggag agaagtcagg
    12781 gtgaaagttt ccttgattgt ctcgtgctcg catgtaacct gtctcagcgt caaatagctg
    12841 gcggtaattt tgtgaagcag ccttgtaggt ttcagcgatt tctatgtttt ttagtttttt
    12901 ggcacagttg gcgatacaaa agtcactata ggcatagtct agagtatggc taacactttc
    12961 gtggtggtcg gtagagaggt aacctagttc ttggtattgg gctagtccgt ggcggccatt
    13021 gatgccgaga gggtcggctt tgctggctgt tttgagcatg gcttggaaga gttctccttc
    13081 taggtcgggg gccatgtcct tgcaggcgct atctgcgata ataccgtcta aaagtgtacc
    13141 tggcatcata ccccgttcat ctggagccag ccattttgga aggaaaccag tatcgcggta
    13201 gctattgagg aaaccttcta aaaagcgttg atagtgctcc ggtatgataa gggcaaagag
    13261 ggggaaggtg gtgcggaagg tatcccagaa accattgttg ctaaagagga caccaggctt
    13321 gacagtacca gtagccagat ccatgtggat ggcttgccct gactcatcaa cctcataaaa
    13381 agtctgtggg aagaggaaga gtctgtagag acagtggtca aagaaggttc ggttagcctc
    13441 tcctgtctct ataacatcaa aacgatggag gagattttcc caatccgctt gggcacttgc
    13501 tttacagcta tcaaaatctt cttgaggtag attgattaga gcttgagaag gagagatgaa
    13561 agaagtggct agttgcatct cggtttgact acttgctaag tcaattcgcc agtctccagc
    13621 ttcttggctg atagcaagaa tatccgtgtt catttgcagg gcagtgaaca tcgttagcga
    13681 atttttgttg gtttcagttt taccttcttg tcgcagggca agagttcgct tatctacttg
    13741 ctctactgtc agttcatctg ctgcgtgaag atagagggag agggctttgc cttgcttttg
    13801 cttcaaacga atagaagcac cgtagcaagt cggtgtgagc tgggtttcaa tttgatagcg
    13861 cagggagaaa atctttagat aatgaggttg gaaagaggcc ttatccctat cataggaaga
    13921 ttggcggtga aagagactgt ctcccccaag ctgacctgtg acaggtgtca gaaggagcca
    13981 agagtagtcc ccaatccaag gactgggctg gtgagttaat cgaatcccct gaaagatagg
    14041 cagatgcgga tcgaagaacc aagatccatc ctggtcactg gtctggggca caaagtaatt
    14101 catcccaaaa ggcacgcctg tgtatggcag ggtatttccc cgagaaaagg catgcttgtt
    14161 ggtagttccc aagcgggtat cgatggtttc aagtagtggt ttcatagtct ttcctttagc
    14221 tgtttttcta cattatatca gaaaaagagg gcctttagaa aaggagtttc aaagataact
    14281 attttgtaga aaaatgacta tcatttgtgt atgtattttc tgtctcaaaa gctatatact
    14341 gaaaatgaaa cttgtttgaa agagggaatt gcacgatgat ttattcgaaa gaaattgtta
    14401 gagaatggct agatgaagta gcagagcggg ctaaggacca tccagagtgg gtggatgttt
    14461 tcgagcgttg ctacaccgat accttggaca atacggttga aatcttagaa gatggttcaa
    14521 cttttgtctt gactggggat attcctgcca tgtggcttcg agattcgaca gcccaactca
    14581 gaccctacct tcatgtagct aaaagagatg ccctcctgcg tcagaccatt gcaggtttgg
    14641 tcaaacgtca gatgaccttg gtactcaagg atccctatgc taactccttc aacattgaga
    14701 agaactggaa agggcaccac gagactgacc acacagacct taacggctgg atctgggagc
    14761 gcaagtatga ggtggattca ctttgctatc ctttgcagtt ggcttatctc ctctggaaag
    14821 agactggcga gactggtcag tttgatgaga cttttgtcgc agcgactaag gaaattctcc
    14881 atctatggac agttgaacaa gaccacaaga actctcctta tcgttttgtc cgagatacgg
    14941 accgtaagga agacaccttg gtaaatgatg gctttggacc tgactttgca gtgacaggta
    15001 tgacttggtc agcttttcgt ccgagtgacg attgctgtca gtatagttac ttgattccgt
    15061 ctaatatgtt tgccgtagta gtcttgggtt atgtgcaaga aatctttgtc gaattagacc
    15121 tagctgatag ccagagtgtt attgctgatg ccaagcgtct tcaggatgaa atccaagaag
    15181 gaatcgaaaa ctacgcttac accaccaaca gcaagggcga aaagatttac gcttttgaag
    15241 tagatggcct aggaaatgcc agcatcatgg atgatccaaa tgtaccaagt ctactagctg
    15301 cgccctatct gggctactgt tcgatcgatg atgaagtgta tcaagccact cgccgtacca
    15361 ttctgagctc tgaaaatcca tacttctacc aaggagaata cgctagcggt ctcggaagtt
    15421 ctcatacctt ctatcgctat atctggccaa tcgccctttc tatccaagga ttgacaacaa
    15481 gagataaggc agagaaaaaa ttcttgctgg atcagctggt tgcctgcgat ggtggtacag
    15541 gtgtcatgca cgaaagcttc cacgtagatg atccgaccct ctactctcgt gaatggttct
    15601 cctgggctaa catgatgttc tgtgagttgg tcttggatta cttggatatt cgctaagggg
    15661 ctcgctttag ctcaaccgat tcttatcaga atcacaagtt tacatttaaa acgttaaaat
    15721 ttaaatttag aatgaggttt tacttcatgg aaaatgttgt tgtacatatt atctcacata
    15781 gtcactggga ccgtgagtgg tacttgcctt ttgaaagcca tcgtatgcag ttggtggaat
    15841 tgtttgacaa tctctttgat ctctttgaaa atgaccctga gttcaagagt ttccacttgg
    15901 atggacaaac tattgtcctt gatgactact tacaaattcg ccctgaaaat cgcgacaagg
    15961 tccaacgcta cattgacgag ggcaaactta aaattggtcc cttttacatc ttgcaggatg
    16021 actacttgat ctccagtgaa gccaatgtcc gcaatacctt gattggtcaa caagaagctg
    16081 ccaaatgggg taaatcaacc cagattggct actttccaga tacctttgga aatatgggac
    16141 aagcgcctca aattcttcaa aaatcaggca ttcacgtggc ggcctttggt cgtggtgtga
    16201 agccgattgg atttgacaac caagtccttg aagatgagca gtttacatcc cagttttcag
    16261 aaatgtactg gcagggtgtg gatggtagtc gtgttttagg tattctcttt gccaactggt
    16321 acagtaatgg gaatgaaatc ccagttgaca aagatgaggc cttgaccttc tggaaacaaa
    16381 aattgtcaga tgtgcgtgcc tacgcttcga ccaaccaatg gttgatgatg aacggctgtg
    16441 accaccagcc tgtacagaaa aatctgagcg aagccattcg tgtggcaaat gaactcttcc
    16501 cggatgtaat ctttgttcat agttcttttg atgaatatgt tcaagctgta gaaggtgcgc
    16561 ttcctgaaca cttatcaact gttacaggcg agttgaccag tcaggaaaca gatggctggt
    16621 acacacttgc caacacttct tcatcccgca tttacctaaa acaagccttc caagaaaata
    16681 gcaacctcct agagcaagtg gtagaaccct tgactattat cactggtgga cacaaccaca
    16741 aggaccagtt gacctatgct tggaaaacac ttttgcagaa tgcgccacat gatagtatct
    16801 gtggctgtag cgtggacgaa gttcaccgcg agatggaaac gcgttttgcc aaggtcaacc
    16861 aagtaggaaa ctttgttaaa agtaacttgc tcaacgagtg gaagggtaaa attgctacgg
    16921 ataaggctca aagtgactat ctctttactg tcattaacac aggcttgcat gataaggtcg
    16981 atactgtcag cacagtgatt gatgtggcga cttgtgattt caaggtattg cacccaacag
    17041 aaggctacaa aaagatggct gctcttatct tgccaagtta ccgtgtggag gacttggatg
    17101 gtcatcctgt agaggctaca atcgaagacc tcggagctaa ttttgagtat gatttaccaa
    17161 aagacaagtt ccgccaagct cgtattgctc gtcaagtgcg cgtgaccatt ccagttcacc
    17221 tagcgccgct ttcttggaca accttccaat tgctggaagg aaaacaagaa caccgtgagg
    17281 gtatttacca aaacggagtg attgatacac cattcgtaac ggtgagtgtg gatgacaaca
    17341 tcacagtcta tgacaagaca actcacgaag cctatgaaga ctttatccgc tttgaagacc
    17401 gtggggacat cggaaacgag tatatctatt tccaaccaaa aggaacagag ccaatctttg
    17461 cagaacttaa gggccacgag gtcttggaaa acacagcttg ctatgctaaa atcttgctca
    17521 aacatgaatt gaccgtgcct gtcagcgcgg atgaaaagct agaagaagag caacaaggta
    17581 tcatcgagtt tatgaagcgt gaggctggac ggtcagaaga attgacaaac attcctctgg
    17641 aaactgagtt gactgtcttc gttgacaatc cacaaatccg cttcaagact cgctttacta
    17701 acactgccaa ggatcaccgt atccgtctct tggtcaagac tcataacacg cgtccaagca
    17761 atgattctga aagtatctat gaggtggtga cacgaccaaa caaaccagct gcttcatggg
    17821 aaaatcctga aaatcctcaa caccaacaag cttttgtcag tctgtatgac gatgaaaaag
    17881 gggtgactgt atccaataag ggattgaatg aatacgaaat ccttggggat aacaccattg
    17941 ccgtgaccat tttgcgtgca tcaggtgagc taggtgactg gggctacttc ccaacgccag
    18001 aagcacaatg cttgcgtgag tttgaagtcg agtttgcact tgaatgccac caagcccaag
    18061 aacgcttctc agcctatcgt cgtgccaaag ccttgcagac accgtttacc agccttcagc
    18121 ttgctagaca ggaaggaagc gtggttgcga ctggtagcct cttgagccat tctgttctca
    18181 gcataccgca agtttgtcca acagccttta aagtggcgga aaatgaagaa ggctatgtcc
    18241 tccgttacta taatatgagt caagaaaatg tgcgcatatc agaacatcaa caaaccattc
    18301 ttgacttact tgagcgacca tatccagttc attcaggact attggctcca caagagattc
    18361 gtacagaatt catcaaaaaa gaagaaattt aatttcaaaa agtaaacatc aaaagaaagg
    18421 aggggcgaaa aagtaagaac taactgctga ttcgcccctt tttatggtaa aaacaatgac
    18481 cattgcaacg attgatatcg gagggactgg gattaagttt gccagtctga ctcctgatgg
    18541 gaaaatactg tataagacaa gtatttcaac gcctgaaaac ttggaggatt tactagcgtg
    18601 gctagatcaa cgcttgtcag aacaggatta cagtgggatt gctatgagcg ttccaggtgc
    18661 ggtcaatcaa gagacaggtg tgattgatgg cttcagtgcg gtgccctaca tccatggctt
    18721 ttcttggtat gaggcgctta gctcttatca gctacctgtc catttagaaa atgatgccaa
    18781 ctgcgttgga ctcagtgaac tactagctca tccagagctt gaaaatgcag cctgtgtcgt
    18841 gattgggaca gggattggcg gagccatgat tatcaatggt agacttcatc gaggtcgcca
    18901 cggtctgggt ggagaatttg gctacatgac aacccttgcc cctgctgaaa aacttaataa
    18961 ctggtcgcaa ctagcatcaa ctgggaatat ggtacgatac gtgattgaaa aatctggtca
    19021 tactgattgg gacggtcgca agatttacca agaggccgca gctggtaatg ctctttgtca
    19081 agaagccatt gagcgcatga accgcaatct gacgcaaggc ttgctcaata tccagtatct
    19141 gatcgatcca gatgtcatca gtctgggtgg ctctatcagt caaaatccag attttatcca
    19201 aggtgttaag aaggctgttg aagactttgt cgatgcctac gaagaataca cggtcgcacc
    19261 agttatccag acctgcacct atcacgcaga tgccaatctc tacggtgccc ttgtcaactg
    19321 gctacaggag gaaaagcaat ggtaagattt acaggactta gtcccaaaca aacgcaagct
    19381 attgaggttt taaaaggtca tatttctcta ccagatgtgg aagtggctgt cactcagtct
    19441 gaccaagcct ctatctctat cgagggtgag gaaggtcact atcaattgac ctaccgcaaa
    19501 cctcaccaac tttatcgtgc cttatccttg ttggtaacag ttctagcaga agctgataaa
    19561 gtagagattg aggaacaagc agcttacgaa gatttggctt acatggttga ctgttctcga
    19621 aatgcggtgc tgaatgtggc ttctgccaag cagatgattg aggtcttggc tctcatgggc
    19681 tactcaacct ttgagcttta catggaagac acttaccaga ttgaaggaca gccttacttt
    19741 ggctatttcc gtggagctta ttcagcagag gagttgcagg aaatcgaagc ctatgcccaa
    19801 cagtttgaca tgacctttgt accatgcatc cagaccttgg cccacttgtc ggcctttgtc
    19861 aaatggggtg tcaaggaagt ccaggagctc cgtgatgtag aggacattct tctcattggc
    19921 gaagaaaagg tttatgacct gattgatggc atgtttgcca cgttgtctaa actgaagact
    19981 cgcaaggtca atatcgggat ggacgaagcc cacttggttg gtttgggacg ctacctgatt
    20041 ttgaacggtg ttgtggatcg tagtctcctc atgtgccaac acttggagcg cgtgctggat
    20101 attgctgaca aatatggttt ccactgccag atgtggagtg atatgttctt caaactcatg
    20161 tcagcggatg gccagtacga ccgtgatgtg gaaattccag aggaaactcg tgtctaccta
    20221 gaccgtctca aagaccgtgt gactctggtt tactgggatt attatcagga tagcgaggaa
    20281 aaatacaacc gtaatttccg caatcatcac aagattagcc atgaccttgc atttgcaggg
    20341 ggagcttgga agtggattgg ctttacacct cacaaccatt ttagccgtct agtgactatc
    20401 gaggctaata aagcctgccg tgccaatcag attaaagaag tcatcgtaac tggttgggga
    20461 gacaatggtg gtgaaactgc ccagttctct atcctaccaa gcttgcaaat ctgggcagaa
    20521 ctcagctatc gcaatgacct agatagtttg tctgcgcact tcaagaccaa tactggtcta
    20581 acggttgagg attttatgca gattgatctt gccaacctct taccagacct accaggcaat
    20641 ctcagcggta tcaatcccaa ccgctatgtt ttttatcagg atattctttg tccgattctt
    20701 gatcaacaca tgacacctga acaggacaaa ccgcacttcg ctcaggctgc tgagacgctt
    20761 gctaacatta aagaaaaagc tggaaactat gcttatctct ttgaaactca ggcccagttg
    20821 aatgctattt taagtagcaa agtagatgtg ggacgacgca ttcgtcatgc ctaccaagcg
    20881 gatgataaag aaagtttaca acaaatcgcc agacaagaat taccagaact tagaagccaa
    20941 attgaagact tccatgccct ctttagccac caatggctga aagaaaacaa ggtctttggt
    21001 ttggatacag ttgacatccg tatgggcgga ctcttgcaac gcatcaaacg agcagaaagc
    21061 cgtatcgagg tttatctggc tggtcagctt gaccgcatcg acgagctgga agttgaaatc
    21121 ctaccattta ctgacttcta cgcagacaag gacttcgcag caactacagc taaccagtgg
    21181 cataccattg cgacagcgtc gacgatttat acgacttaat actcttcgaa aatctcttca
    21241 aaccacgtca gcttccatct acaacctcaa aacagtgttt tgagcagcct gcagctagct
    21301 tcctagtttg ctctttgatt ttcattgagt ataaaaacaa gaacaccttg cttggcgcag
    21361 ggtgtttcgc gtgaaacaga agaattatct ggtttcaaat gctacagtta gacaaactta
    21421 tgataaaata gcagaaagtg aatgtttcct aagagcaatt ctatcgatga gcaattggag
    21481 gtattatgct acacttaaaa ttagtaaaac aagaaataga agcttgggtc atttccgtca
    21541 aatttaaaaa aggttgctac cgacatatat agattccaaa aacaaaaacg ttagcgaaac
    21601 tagcagatgt gattttatgg agttttgatt ttgcaaatga tcatgctcac gcatttttca
    21661 tggataatgt tgagtggagt catgcagatt cttacttttt tagctttgtt agtgacgatg
    21721 ttgaagaacg ttacacagaa aatgtctatc tggatagcct aagtgtcaaa caaaaattta
    21781 agtttatttt cgacttcggt gatgaatggc gttttgaatg ccaagtgctg agagaaatcg
    21841 agacagagga cgaagaagct tatctcgtac gttcggttgg aacgtcgcca gaacaatatc
    21901 cagattatga tggttttgac tatgaagaat ggtaaaattg aaatcagtct gtgtaggctt
    21961 agtatttcaa tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca
    22021 ctcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaattatt
    22081 ttaaacgttt ttactttggc aaagatgttc tcaaccttgc ttctctcctt ggatagcgca
    22141 tggttacagg ctttatcttc aactgttagc ggcttgagtt tgctggattt acgtggagtt
    22201 tgtgcttgag gatatatctt catgagccct tgataaccac tgtcagccaa gattttacca
    22261 gcttgtccga tatttctgca actcattttg aacaacttca tatcatgaca atagttcaca
    22321 gtgatatcca aagaaacaat tctcccttga cttgtgacaa tcgcttgagc cttcatagcg
    22381 tgaaatttct ttttaccaga atcattcgct aattgttttt ttagggcgat tgatttttac
    22441 ttccgtcgca tcaatcatta ccgtgtcctc agaactgaga ggagttcttg aaaccgtaaa
    22501 accactttga acaagagtta cttcaaccca ttggctccga cggataaagt tgctttcgtg
    22561 aataccaaaa tcagccgcaa tttcttcata agttcgatat tctcgcacta ttgaagagtg
    22621 ggcataagaa ggtcttctag gcttaattta ggttttcgtc caccttttgc gtgtttaagt
    22681 tgataagctg tttttaatac agctaacatc tcttcaaaag tcgtgcgttg aacaccaaca
    22741 agacgcttaa atcgtgcatc ggttagttgt ttacttgctt cataattttg tttcgcaggg
    22801 agtctattga ctctttggta ggtgtcaatg tttttttcat ctatcccgag aattattttc
    22861 ccgccatttg tatttgcaaa tgctgagtag gtttcccaga aagactctgg aagattgttt
    22921 ttagcttttt tgtattctaa atcaacccct tcaaatttta agtccatatt tttcctttac
    22981 atctgttttt tgtggttctg gtatttgttc aagttgagtg ataatatagc gaattgaatt
    23041 tcgagagttt ttactcagtt aatttctttt ttaacccact ttaatttctt ttttaacacg
    23101 ggttaaaaaa gaaattaaag tgggttaatt ttccttgact taaaatttaa aaatgatata
    23161 ctgtgtttat ggagagatga caatttataa aatgtactac tctattctac tagataatga
    23221 ttgaataaaa ctttttataa caacggctag caaagttata attttatatc tattagaaaa
    23281 taaatatgta aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg
    23341 gttattttag cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa
    23401 gtaatcaaag agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt
    23461 ctaactgtag aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag
    23521 tttgaagctg gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat
    23581 aaagtattta ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca
    23641 ggtagaattg tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa
    23701 aaaaaaggct tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg
    23761 gagaaaattg aagatagagc ttttgatttt tctgaattag aagagattga attgcctgca
    23821 tctctagaat atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc
    23881 ttttcctcaa gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat
    23941 ttagagaaac taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc
    24001 actactagct taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat
    24061 ggtgttttgt tttcaaaaga taaaactcaa ttaatttatt atccaagtca aaaaaatgac
    24121 gaaagttata aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat
    24181 tcttacttga aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt
    24241 gcggatgcga ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt
    24301 ttagcctttt acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat
    24361 tttggtaaac acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat
    24421 atcaactcat tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat
    24481 attaagaata aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact
    24541 gttaagttct atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact
    24601 agtaatgata tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa
    24661 cctaaaaaga attctaatca gggagtag
//
LOCUS       DBERAE010000032        24085 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.32, whole genome shotgun sequence.
ACCESSION   DBERAE010000032 DBERAE010000000
VERSION     DBERAE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.32"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..738
                     /locus_tag="ACL70N_001483"
     CDS             <1..738
                     /locus_tag="ACL70N_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS0590264.1"
                     /translation="PAPKPAPAPKPAPAPKPAPAPKPETPKTGWKQENGMWYFYNTDG
                     SMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWYYLNT
                     NGAMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYYL
                     NANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKW
                     YYVNGLGALAVNTTVDGYTVNENGEWV"
     gene            1139..2260
                     /gene="mnmA"
                     /locus_tag="ACL70N_001484"
     CDS             1139..2260
                     /gene="mnmA"
                     /locus_tag="ACL70N_001484"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGS0590265.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2401..2856
                     /locus_tag="ACL70N_001485"
     CDS             2401..2856
                     /locus_tag="ACL70N_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0590266.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGISYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2866..4779
                     /gene="mnmG"
                     /locus_tag="ACL70N_001486"
     CDS             2866..4779
                     /gene="mnmG"
                     /locus_tag="ACL70N_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGS0590267.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWASFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4974..6653)
                     /locus_tag="ACL70N_001487"
     CDS             complement(4974..6653)
                     /locus_tag="ACL70N_001487"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS0590268.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6655..6888)
                     /locus_tag="ACL70N_001488"
     CDS             complement(6655..6888)
                     /locus_tag="ACL70N_001488"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGS0590269.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7168..7383
                     /locus_tag="ACL70N_001489"
                     /pseudo
     CDS             7168..7383
                     /locus_tag="ACL70N_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7706..7858)
                     /gene="cibB"
                     /locus_tag="ACL70N_001490"
     CDS             complement(7706..7858)
                     /gene="cibB"
                     /locus_tag="ACL70N_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGS0590270.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7860..8045)
                     /gene="cibA"
                     /locus_tag="ACL70N_001491"
     CDS             complement(7860..8045)
                     /gene="cibA"
                     /locus_tag="ACL70N_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGS0590271.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8223..8906
                     /gene="tsaB"
                     /locus_tag="ACL70N_001492"
     CDS             8223..8906
                     /gene="tsaB"
                     /locus_tag="ACL70N_001492"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGS0590272.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8903..9340
                     /gene="rimI"
                     /locus_tag="ACL70N_001493"
     CDS             8903..9340
                     /gene="rimI"
                     /locus_tag="ACL70N_001493"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGS0590273.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9330..10340
                     /gene="tsaD"
                     /locus_tag="ACL70N_001494"
     CDS             9330..10340
                     /gene="tsaD"
                     /locus_tag="ACL70N_001494"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGS0590274.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10380..11686)
                     /locus_tag="ACL70N_001495"
                     /pseudo
     CDS             complement(10380..11686)
                     /locus_tag="ACL70N_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12022..12713)
                     /locus_tag="ACL70N_001496"
                     /pseudo
     CDS             complement(12022..12713)
                     /locus_tag="ACL70N_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12956..13510
                     /locus_tag="ACL70N_001497"
     CDS             12956..13510
                     /locus_tag="ACL70N_001497"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0590275.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            13638..14099
                     /locus_tag="ACL70N_001498"
     CDS             13638..14099
                     /locus_tag="ACL70N_001498"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0590276.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHESI"
     gene            14123..15076
                     /locus_tag="ACL70N_001499"
     CDS             14123..15076
                     /locus_tag="ACL70N_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0590277.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            15086..16702
                     /locus_tag="ACL70N_001500"
     CDS             15086..16702
                     /locus_tag="ACL70N_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0590278.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16963..17391
                     /locus_tag="ACL70N_001501"
     CDS             16963..17391
                     /locus_tag="ACL70N_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590279.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17403..18152
                     /locus_tag="ACL70N_001502"
     CDS             17403..18152
                     /locus_tag="ACL70N_001502"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGS0590280.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFQYVSDSSMVGYMGKTKELKMYQEELDEKNYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            18165..19337
                     /locus_tag="ACL70N_001503"
                     /pseudo
     CDS             18165..19337
                     /locus_tag="ACL70N_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            19732..20595
                     /locus_tag="ACL70N_001504"
     CDS             19732..20595
                     /locus_tag="ACL70N_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0590281.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRFGRKVVDRFAHQDIVGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIGHFIQSLQVLENPQLIVLFE
                     LRLQQYKKLID"
     gene            20881..21114
                     /locus_tag="ACL70N_001505"
     CDS             20881..21114
                     /locus_tag="ACL70N_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590282.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            21136..21813
                     /locus_tag="ACL70N_001506"
     CDS             21136..21813
                     /locus_tag="ACL70N_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0590283.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            21825..22490
                     /locus_tag="ACL70N_001507"
     CDS             21825..22490
                     /locus_tag="ACL70N_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0590284.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            22562..23788
                     /locus_tag="ACL70N_001508"
     CDS             22562..23788
                     /locus_tag="ACL70N_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0590285.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISEILPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7326 a         4104 c         5123 g         7532 t
ORIGIN      
        1 ccagctccta aaccagctcc ggctcctaaa ccagctccgg ctcctaaacc agctccagct
       61 cctaaaccag aaactccaaa aacaggctgg aaacaagaaa atggtatgtg gtacttctac
      121 aatacggatg gttcaatggc aacaggctgg ctacaaaata atggctcatg gtactacctc
      181 aacgctaatg gtgctatggc aacaggttgg gctaaagtca acggcttatg gtattacctc
      241 aacagcaatg gcgctatggc gacaggatgg ctccaataca atgattcatg gtactacctc
      301 aatactaatg gtgctatggc gacaggttgg ctagaataca atggttcatg gtactacctc
      361 aacgctaatg gtgctatggc gacaggttgg ctagaataca atggctcatg gtactacctc
      421 aacagcaatg gcgctatggc gacaggttgg ctccaataca atggttcatg gtactatcta
      481 aacgctaacg gcgctatggc aacaggttgg gctaaagtca acggttcatg gtactacctc
      541 aacgctaacg gttcaatggc aacaggttgg gtgaaagatg gagatacctg gtactatctt
      601 gaagcatcag gtgctatgaa agcaaaccaa tggttcaaag tatcagataa atggtactat
      661 gtcaatggct taggtgccct tgcagtcaac acaactgtag acggatatac tgtcaatgaa
      721 aacggtgaat gggtttaagc cgattaaatt aaatcatgtt aagaacattt gacattttaa
      781 ttttgaaaca aagataaggt tcgattgaat agatttatgt tcgtattctt taggtaccta
      841 tcttatgatt tcaggaaatg tcattaaaaa aacgactcct tttctctaac ttgaaaaata
      901 gattagagaa aatgggttgt tttatttatt atagttattt gaatgaagat aagaagaagg
      961 tatactcaca tcattcacat aatctgtata ttgactataa gttttaaaaa acaattttta
     1021 agctcttcct tgtcttctct aaccaagcgt gttataatga atactgctca agcgaccttc
     1081 aatcgtgaag cacacacgac cttcaatcgt gaataaacga atagatggga gacttaccat
     1141 gagtgataac tctaaaacac gtgttgtcgt ggggatgagt ggtggtgttg attcgtcggt
     1201 gacggctctt ttgctcaagg agcagggcta cgatgtgatc ggtatcttca tgaagaactg
     1261 ggatgacaca gatgaaaacg gcgtctgtac ggcgaccgaa gattacaagg atgtggttgc
     1321 ggtggcagac cagattggca ttccctacta ctctgtcaat tttgaaaaag agtactggga
     1381 ccgcgttttt gagtatttcc tagcggaata ccgtgcaggg cgcacgccaa atccggacgt
     1441 tatgtgcaac aaggaaatca agttcaaggc ctttttggac tatgccataa ccttgggggc
     1501 agactatgta gcgactgggc attatgctcg agtggcgcgt gatgaggatg gcactgttca
     1561 catgcttcgt ggcgtggaca atggcaagga ccagacctat ttcctcagcc aactttcgca
     1621 agaacaactt caaaaaacca tgttcccact aggacatttg aaaaagcctg aagttcgaaa
     1681 actagcagaa gaagcaggtc tttcgactgc taagaagaaa gactcgacag ggatttgctt
     1741 tatcggagaa aagaacttta aaaactttct cagcaactac ctgccagctc agcctggtcg
     1801 tatgatgact gtggatggtc gtgatatggg cgagcatgct ggtcttatgt actatacaat
     1861 cggtcagcgt ggcggactcg gtatcggtgg gcaacacggt ggtgacaatg ccccttggtt
     1921 cgttgtcgga aaagatctaa gcaagaatat tctctatgta ggccaaggtt tctaccatga
     1981 ttcgctcatg tcaaccagcc tagaggctag ccaagtccac tttactcgtg aaatgccaga
     2041 agagtttacg ctagaatgta cggctaaatt ccgttaccgt cagcctgact ctaaggtgac
     2101 cgtccatgtc aaaggagaca aggcagaagt tatctttgcg gaaccacaac gcgcgattac
     2161 accaggacag gcagttgtct tttacgatgg cgaagagtgt ctaggtggcg gtttgattga
     2221 caatgcttac cgcgatggac aagtttgtca gtacatttag attgacaaat tttctcaatt
     2281 tgctacaata ataacagcaa tagaaatgat ggtcaaagct catggatgtt gcaggctttt
     2341 ttgtcctgca cttctttgga gttttgactg tttttgtgtc gtttaaggga aaggacaaga
     2401 atgactcaac aagactttcg gacaaaagta gacaatacgg tttttggtgt tcgggcgaca
     2461 gccttgattg tccaaaatca caagcttcta gtcaccaaag acaagggcaa gtattacatt
     2521 atcggcggtg cgattcaagt taacgaaaaa acggaagacg cggtagtccg tgaagtgaag
     2581 gaagaactgg gtgttaaagc tcaagctggg cagctagctt ttgtggttga aaatcgtttt
     2641 gaagtggacg gcatttccta tcacaatatc gagtttcatt atctggtgga tttgcttgaa
     2701 gatgccccgt tgaccatgca ggaagatgag aaaaggcagc cctgtgagtg gattgacttg
     2761 gataagcttg aggatatcca gctagttcca gcctttttaa aaacagccct accagattgg
     2821 gaaggccaac taagacacat tcatcttgag gaataggaga gaaacatgac ttatcatttt
     2881 actgaagaat acgatattat tgtaattggt gcgggacacg ctggggttga ggcttccttg
     2941 gccgctagcc gtatgggctg taaggtcctg cttgcgacca tcaatattga aatgctggct
     3001 ttcatgcctt gtaatccctc tatcggtggt tctgccaagg ggattgtcgt gcgtgaagtc
     3061 gatgccctcg gtggcgagat ggccaagact attgacaaga cttacatcca gatgaagatg
     3121 ctcaacacag ggaaggggcc agctgttcgt gctcttcgtg cgcaggctga caaggaactt
     3181 tactctaagg aaatgcgcaa gacagttgaa aatcaagaaa atctgaccct tcgtcaaacc
     3241 atgattgatg agattttggt ggaagatggt aaggttgtcg gtgtgcgtac agccacccat
     3301 caagaatatg ctgctaaggc tgttattgtg acgacaggga ctgctctccg tggggaaatt
     3361 atcatcggag acctcaagta ctcatcaggt cctaaccaca gcttggcttc tattaaccta
     3421 gctgacaatc tcaaggaact gggtctcgaa atcggtcgtt tcaagacagg aacccctcca
     3481 cgtgtcaagg cctcttctat caactacgac gtgacagaaa tccaaccagg agatgaagca
     3541 cctaatcact tctcatacac ttcacgtgat gaggattatg tcaaggacca agtaccatgc
     3601 tggttgacct acaccaatgg taccagtcat gagattatcc aaaacaacct ccaccgtgcg
     3661 cctatgttta caggtgtggt caagggagtg gggcctcgtt actgtccgtc gattgaagac
     3721 aagattgtgc gctttgcgga caaggaacgt caccaactct tccttgagcc agaagggcgc
     3781 aatactgagg aagtctatgt tcaaggactt tcaaccagtc tgcctgagga tgtccagcgt
     3841 gacttggttc attccatcaa aggtttggaa aatgcagaga tgatgcggac aggttatgct
     3901 attgagtatg atatggtctt gcctcatcag ttgcgtgcga ctttggaaac caagaaaatc
     3961 tcaggtctct tcactgctgg tcagacaaat ggaacatcag gttatgaaga agctgctggc
     4021 caagggatta tcgcgggtat caatgcggct ctgaaaatcc aaggcaagcc tgagttgatt
     4081 ttgaagcgca gtgacggtta tatcggggtg atgatcgacg acttggtgac caagggaacc
     4141 attgaaccct accgtctctt gacaagtcgt gctgaatacc gtctcattct tcgtcatgac
     4201 aatgctgata tgcgcttgac tgagatggga cgcgagattg gccttgtgga tgatgaacgc
     4261 tgggctagtt ttgaaatcaa gaaaaatcaa tttgataatg agatgaaacg cctagacagt
     4321 atcaaactca agccagtcaa ggaaaccaat gctaaggttg aggaaatggg cttcaagccg
     4381 ttgacagatg cggtgacagc caaggaattc cttcgccgtc cagaagtttc ttaccaagat
     4441 gtggtggcct tcatcggacc agctgcagaa gacttggatg acaagattat cgaattgatt
     4501 gaaacagaaa tcaagtacga aggctatatt tccaaagcca tggatcaggt tgccaagatg
     4561 aaacgtatgg aagaaaaacg cattccagcc aatatcgact gggatgacat cgattctatt
     4621 gcgacggaag ctcgtcagaa gttcaaactc atcaatccag aaaccatcgg ccaagccagc
     4681 cgtatttcgg gagtaaaccc agcagatatt tctattttga tggtgtatct ggaaggtaaa
     4741 aatcgtagta tttctaaaac tcttcaaaaa tcaaaatgat acgtcgtcgg cttcttacga
     4801 atgagttcaa agcttggctt tgattcatct ccaacctccc atagttcccc gaactatggg
     4861 agctaactca agttatgcat tttcctagcc ttctggtctg attttcattg agttttaatc
     4921 tcaaaagaaa gcatagagaa aaacagctcc gaagacgggg ctgttttctt gctttattct
     4981 tcatctggtg tgaggatcat cgggatgatg atcggttcac gttcggtatt ttcatagagg
     5041 aaggggcgaa tagcgttgac aatggcacca ttgacagatt gcacgctagc atccttattt
     5101 ttcagtgcga tacgaatggc attgaagagg atacgctggc tttggcgaat caagtcgcca
     5161 gactctctca tgtagacaaa gcctcggctg aggatgtctg gaccagatag aatcatctgc
     5221 gatttgaagt caacagttgc gactgccaga acgacaccgt cttcagatag atcgcgacga
     5281 tctttgagga cagctgcgcc aatttcaccg atacgatttc catcgacata gatatcttgg
     5341 gcgttgaaat gacctgcgat acgagctgag tcagcagtaa gggcaagcac atcgccattg
     5401 ctcatgataa agatattgtc cttctcaaca ccagtatcca ctgctagtcc agcgtggact
     5461 ttttgcatgc ggtattcacc gtggacaggc atgaagtatt ttggcttaat caagcagagc
     5521 atgagttttt gctcttgctg accaccgtgt ccagatgtat ggatattgtt cactttaccg
     5581 tggataactt cgacaccagc ttcagaaatg atgttaatca gcttgttgac gctagtagtg
     5641 tttccaggga tgggactaga agagaagata acggtatcac ctggttgtaa ttgtacttga
     5701 cggtgggttc cgttggcgat acgagagagg gctgccatag gctcaccctg actacctgta
     5761 cagaggataa gaacttctcc tgcaggataa tctttgattt catttggctc gataaaggtt
     5821 cccttaggag ctttgatgta gccaagatcg attccgttga caatggcctt ttccatagaa
     5881 cgaccaaaga ccgcaatctt gcgtccagtc ttaacagcag cttctgttgc ctgctggaga
     5941 cggaagatat ttgaggcaaa ggatgcaaag atgatacgtc cttcaatacc ttggataatc
     6001 ttcataatgg actgaccaac gactttttca gagttggtaa aggttggtac ttccgcattt
     6061 gtcgagtcag acaggagaca gagcacgcct tcttcaccaa gcgcagccat acgatgcaag
     6121 tccgcaggtt ctccaactgg agtaaagtcg aacttaaagt cacccgtaca gacgattttc
     6181 ccttgaggag tatgaatgac aatccccaaa ggctctggaa tagagtgagt cgttctaaag
     6241 aaagttgcct tgagattttt aaaggtcaac tcggtgttgt ggttgatttc gtaaagtttg
     6301 gcgttgcgca agaggccgtg ttcttcgagt ttcccacgga tcaaagccaa ggcaagcggt
     6361 ccagcataaa tagggacatt tgcttgcttg agtaggaacg gaatcccacc aatgtggtcc
     6421 tcgtgtccgt gtgtgattaa aacagccttg acgcggtcga tattgtctac gatgtaagag
     6481 tagtcaggaa tgacatagtc gataccaagc aagtcatctt ctgggaattt aatcccagca
     6541 tcgacgatga taatctcgtc ttggtattca attccgtaag tgtttttccc gatttctcct
     6601 agaccaccga tggcaaaaac gccgacttct tcaggtttaa gagtgtaggc catattagaa
     6661 ctccgtgatt tcgaaggcgc cagtttcttt ttcgtaatcg agcaatttgt cagacaagag
     6721 ttcgatatat tcgatattgt actctgggcg attttcttcg acaagttggc gagcagtgat
     6781 gcgaccctca agttctgagc tggcatcgat gtctaggtaa agcgcgcgtg ttgtttcacg
     6841 gcgtgggcta cgttcttttg tttcttgata aaaaactttg taaatcatat agttcctttc
     6901 tatttacagg tcagcttatt ccaaactttt agcagatatt tgcttgattt cattccattt
     6961 tgtgtctaga ttgaccttga ttcgttacaa ttatttcaat tataccacaa aatgaaaaat
     7021 tagtaaaaga cggaaacgag aaagttaggg ggcgatttct ttggtaatcg tttgcaaaaa
     7081 taaagaaaat gtgttatgtt gataacggaa gtgaagttta ttacttgtca taattccata
     7141 tagattttaa gtcaaggagg ttgccctatg tataacttat ttgcttttgc tatcggagtt
     7201 cgtttgctag cttttatcgt ttttgttgct tgcgtttatg gaggaaatct tctatttgcc
     7261 aaactggaac gatgacaaac caagttcttg tggaaaatta cctttgtgac tctctactcg
     7321 ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat tttactttgg attaaatgct
     7381 tagatgccct gcttatgctg gttttttttg tttgggaatg tagagatagt agatttacga
     7441 cacgaaaatt ccaccccatc tatcaagatg aggtggtctt tgcatttttc taacatgaca
     7501 tgacaatgga attttcaaag cttattattt ttatgggagt cattgttcta ctcaaaaata
     7561 gagttgaagc ataaaaataa aacaatacaa acagataaat cgaatggtaa agggatggta
     7621 gtaatgttca aatcattgag aatgctgagc aaactgtaag agatgaagac aataaaattt
     7681 atccttctaa aaatgtgttt cttatctagc atgacttacc aaacttttta cgaaggtctt
     7741 ttccaatggt ataacctgcc ataaataaag cgataccaac accgacacca aagccaccct
     7801 tgatttcttg caattcctta ttagaaattt cacgataatt gttcaaatct ttcatcatat
     7861 taatctcctc ctaaaaaata accagctgcc aaaccagaac ctataagtgc tgttccacct
     7921 gcaatagcct tccaagatac tgctactcca aagataacca agggagcgag accgccatca
     7981 atatctgata attcattttc agataaggat aaaaattgat tgtcaagaat gtcaaaattt
     8041 gtcattgaac tttcctcctt ttttcttgtt cacttttata ttcggaaaag aaaaggaaaa
     8101 gtgagcattt ttttaaatta tttttagtta agtgagggca ctcttgtctg ggggcaaaga
     8161 aaattcccat gtgccagctt ttgtagtata atagtaagca gacaaaaaga taggaatgtg
     8221 ttatgaaagt attagctttt gatacgtcca gcaaggctct ttctctggct attttagagg
     8281 ataagcaggt tcttgccgag acgacgatta atattaagaa aaatcacagt attactctta
     8341 tgcctgccat cgattttttg atggcaagtt tggattggac acccaaggat ttggaccgaa
     8401 tcgtggtagc tgaagggccg ggtagctata caggcttgcg aattgcggta gcaactgcta
     8461 agaccttagc ttacaccctg aacattgagt tggttggtat gtctagtctc ttggctctag
     8521 tgccatatca acaagaaggt ttgtttgttc ctttgatgga tgcgcgtcgc aataatgttt
     8581 atgcaggatt ttatgaaaat gccaaacctg tcatggcaga agcacatctg ccttttgagc
     8641 gagtcattga gctaatcaag ggcgctagtc aggtaacctt tgtcggagaa gttggcccct
     8701 ttgttgagca gattcaaaaa cacttgccaa ggactgatta caaagaaaca ttgcccaatg
     8761 cagctaatct agctcttttg gcctgggaca aggaagcaga ctccttgcat gattttgtgc
     8821 caaattacct caaacgtgtt gaggcagagg aaaactggct caagaaccat accgagtctg
     8881 gtgagtctta cattaaacgc ctatgataga aatcaaacgt atccaacagc aacctgcctt
     8941 ggctcaagat atctacgctg tcatggcagc tgtttaccca gtcagtcctt ggacactaga
     9001 acaaatccaa gcagatctgt cccaagacca gacttggtat gctctggcct atgatggggc
     9061 agaagtgatt ggctttctaa ctgttcagga gactctcttt gaagcagaag tcctgcaaat
     9121 cgctgtcaaa ggagcctgtc agggtcaggg aattgcgtca gccttgtttg ctcaattgcc
     9181 gacagacaag gaaattttcc tcgaagttag acagtcaaat caacgagcgc aagcatttta
     9241 caagaaagaa aaaatggcgg tcatcgctga gcgaaaagcc tactaccatg acccagtcga
     9301 ggacgccatt atcatgaaga gagaaataga tgaaggatag atatatttta gcatttgaga
     9361 catcctgtga tgagaccagt gttgccgtct tgaaaaacga cgatgagctc ttgtccaatg
     9421 tcattgctag tcaaattgag agtcacaaac gttttggggg cgtagtgcca gaagtagcca
     9481 gtcgtcacca tgtcgaggtc attacagcct gtatcgagga ggcgctagca gaagcaggga
     9541 ttacagaaga ggacgtgaca gctgtggcgg ttacctatgg accgggcttg gtcggagcct
     9601 tactagttgg tttgtcagct gccaaggcct ttgcttgggc acatggactt ccgctgattc
     9661 ccgttaacca catggctggc catctcatgg cggctcaaag tgtggaacct ttggagtttc
     9721 ccttgctagc cctcttggtt agcggtgggc acacagagtt ggtttatgtt tcggaggcag
     9781 gagattataa gattgttggg gaaacccgtg atgatgcggt tggtgaggct tatgataagg
     9841 tcggccgtgt catgggcttg acctatcctg caggtcgtga gattgacgag ctggctcatc
     9901 aggggcagga tatttatgat ttcccccgtg ccatgattaa ggaagataat ctggagttct
     9961 ccttctcagg tttgaaatct gcctttatca atctttatca caatgccgag caaaagggag
    10021 aaagcctgtc tacagaagat ttgtgtgctt ccttccaagc agcagttatg gacattctca
    10081 tggcaaaaac caagaaggct ttggagaaat atcctgttaa aaccctggtt gtggcaggtg
    10141 gtgtggcagc caataaaggt ctcagagaac gcctagcagc cgaaatcaca gatgtcaagg
    10201 ttatcatccc ccctctgcga ctctgcggag acaatgcagg tatgattgcc tatgccagcg
    10261 tcagcgagtg gaacaaagaa aacttcgcag gctgggacct caatgccaaa ccaagtcttg
    10321 cctttgatac catggaataa agagtggctc tttgtcaagt gtagtgggta ggcgaaaagc
    10381 tacaatctgg agagtacgaa attcgtactc tcttttttga tgttcaaagt catcaaaatc
    10441 cgttttttaa aattgttaaa gttccggaaa ccaaaggctt tgcgcttgat aatcttaatc
    10501 aaattattgg tcgcttcaag tttagcgttg gaataaggca gcttaagtgc gttgataatc
    10561 ttatctctat cccttaaaaa agtccaaaag accgtttgaa aaagcggatg aaccgttggc
    10621 agttcttgct caatcaatcc aaagaaatgg tcggcattct tctcttgaaa atgaaagagc
    10681 aggagttgat agagttcgta gtgaacctgt aatccctcag agtaagaaag cagcttatct
    10741 cgtacttccc gatgggttaa gtgcattcga aacgtgggct gatagaatcg tttctgacag
    10801 agcttgaagc tatactggtg tagtaaatca gtccagtgga ctgatttagc ccgagcctag
    10861 aaacgaaaaa gcgagggttc caaaagcgct tgagcgcccg atactccaag gattttcggt
    10921 caaattggtt catgatttgg attcgtactc ggttcatagc tcggctcaga tgttggacaa
    10981 tgtggaagcg gtcaagaaca atcttcgcct ttggaaagag ttgcttagcg agccgataat
    11041 aagggctgta catgtccatg gtgatgacct cgaccagctc ccgaacctct ctctgatagc
    11101 gttggaaatg gtttcgaatc accgcatgag ttcgcccgtc taaaattgcg aggatggatt
    11161 tggactcaaa atcttgggca atgaagctca ttttgctctt tttgaagcta tactcatccc
    11221 aactcataac ttttggcaac ttggtccaat cggtttcaaa cttaaattcc ctcagttttc
    11281 ggatgacggt ggaagttgag accgccaatc tgtgggcaat ctcagtcata gactgctttt
    11341 caaggaggag ctgagcgatt ttttgtctca ccatgttgga aatctggcaa tttttcttga
    11401 caatggatgt ttgagaaacg accaccttaa ggcaattctt gcactgaaag cggcgctttt
    11461 tgagatgcag taccgtgggt aaaccctgac agtcgagaag cggaatttta gaggctttct
    11521 ggaagtcgta tttgatcatc ttcccttgac aatgaggaca aggaggagcg ggggaatcca
    11581 actttgcctg aacgactaga tgggtttggt atttcagaac agacaagatt ttgatatttt
    11641 tgtcttccaa tccgagcaaa tctgtggtat tcttaagttg ttccatatga accctttcta
    11701 atgagttggt tagacgcttt tcattatagg tcatatgggg ctttttttct acaagaaacg
    11761 accctataat tcctggggtg ggattaccca ctacagaaat tatagagcca aagcattcca
    11821 aagtcttgtc tgactctgga atgttttctg ttcacagttg ttttgtaact gcctaataag
    11881 taaccgcgct ataacgaggt atctaccgag attgtcaatt ctccagtata ctgttataaa
    11941 aaacaaaact ggaggatttt tttatgtccc cccatcgtcc catcgactgt tccgtagctg
    12001 cccaataacg gagtatagtc ggctgaaaca agaataggac aaaagtgcct caagaaaagc
    12061 atcgtaattt gacaatatta ttctgagatg tttttgatgt aagcccatat tttctcaatg
    12121 ggattatact cgggtgaata ggtaggaagt ggtaacagtc tatgccctgc tccttacaca
    12181 tgttcattct gtgaaacctt gcatggtcca taatgataag ggatggtgta tctaaagtag
    12241 gtagtaagaa tttttggaag caagcttcga aaaagtcact cgtcatcgta tctttatagg
    12301 tcatcggagc catagtatat tgaaacaaaa aagggcatta gtacttctat aacagtatcg
    12361 caatctctgg tgtgcgttgt ctcgatctta attcaaataa ttatatcttc ttccagagag
    12421 actaactgcc tgctcaaggc tcgatcatat tcgagataaa aataggtctc aacccctgtc
    12481 tcataaatat aaataggagt caggtagctt aagtgattca attctttaag gaaccgattt
    12541 actttttctg ggtcttgttc gcagtaggta cggctctttt ttagactata tcccatagcc
    12601 tttagagcgt aatgaatagt tgttggagga cagttgaatt cagcagctat ttcagtcaaa
    12661 taagcatcgg gatgagtttc aatatagatt tttaatttat ctctatcaat tttttcaatt
    12721 aatagtggaa gttttcttga agttagtgta ttgaaacgtt tttatacagt gctaaaattt
    12781 gaagtgtagt gcagatggat ttgtaatagt attatagcaa ttctttggag aaggtcgaga
    12841 caagataaaa taggtatctt tgagatataa gcatgattta ctataaaatt attgagttat
    12901 tcataaaaat ttctctatca aatatcataa tgcgtcgttt aaggagatgg ttacaatgca
    12961 atatagttgt ggaaaaataa atattaatat ccctgatgga tatggagaca ttaaggatat
    13021 agtgttttcg gctcatatta tagttaggta taataatgga cattgtggag gtatagatcc
    13081 gcatataatt ggactttgta aaaagcagat cagaaggatg tctctatatc ctattttgat
    13141 aatcgtatct agagattcaa aggttattga tgattataaa aatttagata ttgcctatgt
    13201 tgattgtact caatgttcaa ataattttga aactgcctta cacgttaaaa atattttaaa
    13261 attattaaaa atccaactta tacactgtca tggctactca actaattatt ttttatatat
    13321 gttaaaaaaa cttgacaaga atggatttgg aaaggttaag acagtgataa catgccatgg
    13381 atgggttgaa tataacttaa aaaagaaatt cttgacttat tttgattttt ggacatattc
    13441 tatgggagat gcttttattt gtgtatctga aactatgaaa aaaagattgg agagtataat
    13501 aaaaaaataa gaagatagtt gcaataaata acggaattaa tgtatcaaat agcgatttag
    13561 atgtagtagg tgttcaagac tttaaaaaag aattttgtat tccaaataac aaaaaaatca
    13621 tttgttatgt tggaaggttg gatccagaaa aaaggccgga tagattcctt gaatttgcag
    13681 aaaaattatt tttagtcaga gaagatgtga tttttattat ggctggaaat ggtagtatgt
    13741 gggctgcttt gaaagaaaaa atttgccatt tgaaatgtag agataatttc aggttacttg
    13801 gtgaaatcta tccagctact atagtttacc aaatatcgga tttattgtat attccttctg
    13861 atacagaagg aatacctatg tgtgttttag agtcaatgtc acaaggaact ccggttttag
    13921 ctagtaatgt tggcgggtta agtgaaatta ttgaacatag ggttgatgga tttttatttg
    13981 agaaggaaga tgttgaggga gtgtgtgctt gtgctaattt tttactcaat gattctgagt
    14041 atttgaaata tataggtgag aatagtaaat caaaaataag aaaacatgag agtatatgat
    14101 gaattattag agaagagtag tcatggatag gaatatagat caagaattag taagtattat
    14161 aataccaaca cataataggt atgaatctct gattagagct gtgaaaagtt gtttacatca
    14221 aagttataaa aatatcgaag ttataattat tgatgataat tatagtaatg taaatttaag
    14281 aaataaaatt atccatcaat ttggctatac caatcataga attaagttaa ttttaagtaa
    14341 tgaagattta ggtgcaacta atgccagaaa cataggtatc aaaaattcta gaggtaagta
    14401 tatatcattt ttagacgatg atgatgaata tatgccagat cgaattttaa agttgatggc
    14461 ttgttttaaa aagagtagaa tgaagaattt agctttagtt tatagttatg gaataataat
    14521 ttatccaaat ggtacacgag aagaggagaa gaccgatttt gttggaaatc ccttgtttgt
    14581 tcaaatggtt cacaatatag caggtacgtc attttggttg tgtaaaaaag aggtgctaga
    14641 attaattaat ggttttgaga aaatagattc acatcaggac ggtgttgttt tattaaaact
    14701 acttgctcaa ggataccaaa ttgatatagt gcgagaattc ttggtgaatt actacgctca
    14761 cagtaaagaa aacggtatca ctggagtgac acaaaaaaca attaatgcag atgaagaata
    14821 ttataattac tgtaggaaat attttaattt attgagtttc aacgagagaa tattggttac
    14881 aaagaaatat tattctttaa acataaagcg gttactatta ataggagaca aatgcaaggc
    14941 tttaaaagta atcaagaagg caagagaaga aaaaattttt aacgaatttc tttttttgaa
    15001 atatatgtta ttatatcatt ttggtttttt ctattgtata tatgacaact atgttcaatt
    15061 aaaatttaga aagtgagaaa ctattgtgta tactattata aaatcaaata taaaaaaatt
    15121 tagtttatta acgatattta ttgttgctgg tcaattattg ctaatttatg cagcaactat
    15181 taatgctctg gtgttgaatg aattaattgc gatgaattta gagcggtttt tgaaattgtc
    15241 aatctaccaa atgattgtct ggtgtgggat aatattcctt gactgggtag tgaaaaatta
    15301 tcaggttgaa gtgatccaag agtttaatct agagattcga aatagagttg ccacagacat
    15361 ctctaactct acctatcaag aatttcatag taaatcatca ggaacatatc tttcgtggct
    15421 aaataatgat gttcagactt taaatgatca ggcttttaaa caactttttt tagtaataaa
    15481 aggaatttct ggtactatat ttgcagttgt gactcttaat cactatcatt ggtcattgac
    15541 tgtagccacc ttgttttcat taatgattat gctacttgta ccaaaaatct ttgcatcgaa
    15601 aatgcgagaa gttagtctaa atttaactaa ccaaaatgaa gcttttttaa aatctagtga
    15661 gactatattg aatggatttg atgtgttagc gtccttgaat cttttatatg tattgcctaa
    15721 gaaaattaaa gaagcaggaa ttttattaaa gatggttata caaagaaaga caactgtaga
    15781 aacgttagca ggcgctatta gcttctttct caatattttt tttcagatat ctctcgtttt
    15841 tttaacaggc tatcttgcaa taaaaggaat agtgaaaatt ggtactattg aagcaatagg
    15901 agcactaaca ggtgttattt ttacagcgct aggtgaatta ggaggtcaat tatcctctat
    15961 tattggtacg aagcctattt ttttaaaatt gtattcaatt aatccaattg agtcaaataa
    16021 aatgaatgat atcgaaccaa atgaggtgaa tagagatttt ccgttatatg aagcaaaaaa
    16081 tatttgctat aagtatggag ataaagaaat attaaaaaac ttaaattttt gttttcaacg
    16141 taatgaaaag tatttaattt taggtgaaag tggaagcggg aaatctacat tattaaaatt
    16201 attgaatggc tttttgagag attatagtgg agaattgcga ttctgcgggg atgatataaa
    16261 aaaaacctcc tatttaaata tggtttcgaa tgttctatat gtagatcaaa aagcttattt
    16321 gtttgaaggt acgattagag ataatatttt attggaagaa aattatactg atgaagaaat
    16381 actacagtct ttagagcaag ttggtttgag tgtaaaagat tttcctaata acattttaga
    16441 ttattatgtt ggtgatgatg ggagattact gtcaggaggg cagaaacaaa aaattacttt
    16501 agctagaggg ctaattagaa ataagaaaat agtattaatt gacgagggaa cttctgctat
    16561 cgataggaga acttcgttag cgattgaacg taagatatta gatagagagg atttgactgt
    16621 cattattgtt acccatgctc cgcatccgga acttaaacaa tattttacta agatatatca
    16681 atttccaaag gattttattt aagaatatag gggagggaaa catgagattc tattgtgaag
    16741 cttatgaggt aattactgaa gagaaaaaag tatcattttt ttatgtagat gagaaaccct
    16801 taaggtatct gttatttgac tatatatttc tactagttct agctaaaaaa aaatatccca
    16861 atcttatgaa ctgcacccca aaagttagat ttattctgtc taacttttgg ggtgcagttc
    16921 attttgcata gttttggcat tcatcctaga tatccatata aaatgtctga gattgttgaa
    16981 atgtctaaaa aaatatcaga tctaaacgat aaaaaagaat ttcacaaaaa gaactgtgag
    17041 ttgaggtttc aagatagtgt tcttgataac ataaatagtg tcccgggtac aactcattta
    17101 tttagttgtt taaatattca aacattagta aaaattattt tatatatttt tcgatacaac
    17161 agttgtatga aaatatttaa ttttagagat aaagagctta tcttttttaa taagattgta
    17221 aatgggctga tacaaaatat tgaggagaat ttagaggatg atattgaaag gatattgaaa
    17281 tatttatata tatgtttatt taacgaaata ttcattatta agaataaggt gaattttttt
    17341 gatgatgtgg aatttaatca gacactaagt gagtttttag ataaattgta gagggaatgg
    17401 ttatgagtaa caatactaag tatatctttt tatctccaca tttagatgac gcaatttttt
    17461 cctgtggtga ttatatttca aaattaactt cagaaggaga aattgtactt gttattacta
    17521 tattttctgg ttaccctttg agccaacagc tacagccctc tgctaagcaa tttcataagt
    17581 tgtgtaacct tgggaaatat ccgattgaag aaaggaagaa agaagacagg ttagcttgtg
    17641 aacgtctaca atgtgatttt agacacttat cgtactatga atgtctctat aggaaagata
    17701 gaaatggcaa ttttctatac cgtcatatct atagtgaatt aaaaaatgag gacacattaa
    17761 agaatgatat cataaaagag ctgttaatgc atttagacga caaatgtgtc gtatattgtc
    17821 cgctttcact tggtgaccat gttgatcatg tttttgtgaa tagtattgga agggcgcttg
    17881 aatttatgcg ttataaagta atatattatg aggacttcca atatgtaagt gatagtagta
    17941 tggttggtta tatgggaaaa actaaagaat taaaaatgta tcaagaggaa cttgatgaaa
    18001 aaaattatat tgatagaata tcatcaatat tgtgctataa atctcagatt ttgataatct
    18061 ggaaatcagt tgaaaaactt ttaaacaata ttaaagagtt gtatttaagg aatggggcag
    18121 cttattctat tagattttgg attaagaaat aaggaagtag ttttatgaat atagcagtaa
    18181 ttggtttggg gcatgttggg ctggcctacg cgttactatt tgcatctaaa tataaagttg
    18241 ttgcatatga tatagattct gtaaaaataa ataatttaaa aaagggcatt cttccatcta
    18301 aaaatgaaga gcttatgaag tttttttgcg agaataactt aaatattact ttttttgata
    18361 cattttctga aattaaaaat aatattgatt attatattat tgcgcttccg acagattatg
    18421 atgagaaaat tggtagtttt aatacatatg aaatcgaaca aacggtatcg aagagtctga
    18481 gggtaaaacc taatggaaag attatttgaa agtcaacagt tccgatcggc ttttcaaaca
    18541 aattaaaaag gctgtttgat acaaaaaata tcatttttgt ccctgaattt ttgagagaag
    18601 gttgttctat atatgataat ttatatccaa gtcgcatagt tgttggagat gagacagttg
    18661 aaggaagaaa aattgcagag ttgttccttt cgattagtac tcatagtact gccaatatta
    18721 aaaatgttat gttagtttct cctactgaag cagaagcaat taagcttttt tctaacacat
    18781 tcttagctct ccgtgttgct ttttttaatg aactagattc ttttgctgag aggagaagtt
    18841 taaatgctga agttgtaata aaaggtgttt gtttagatcc aagaattgga aatttttata
    18901 ataatccttc ttttggattt ggaggatatt gtcttcccaa agatactaaa caattaaaaa
    18961 aagaatttat agaaataaat gccccagtga tagaagcgat tgatatttca aacacaaata
    19021 gaaaacagtt catagttaaa caaatattgg aacgaaagcc aaagatagta ggaatatata
    19081 aattggggat gaaatataat tcagataatt acaaagagtc agctatttta agtataatta
    19141 atgaactatt gattgtcggt ataaaaattt tagtatatga accaaattta aacgttagta
    19201 tagataacgt aatttttgaa aagaattttg aactatttac aaaacaaagt gatctaattg
    19261 ttgcaaatag atgggatagg ggccttgaag cttataaaga taaagtttac acaaggggga
    19321 tctggataag agattaacta ttgatattaa aaaggcaata atttataaaa tttgtacaaa
    19381 aaaatgttaa attttcacat tttcatagta tactgtttaa tagaaagtag gttctttgta
    19441 accgctccat tataaaatcc tttcactctt ccggtatact attaggaaaa acataactgg
    19501 aggatatttt gagctcacac ctcatcgttc cagtggctgt tccccaagct cgtgtactgc
    19561 ccaaaaaagt tagacattct atttagaacg aggattgagt tctgtattgt acaaggctcg
    19621 gtccttttag agtcagctta aggctggctt tttcaatcac caaagtgtca gaatgttttg
    19681 acaaaactat aaaaacaatg atatactata taaaaaatag gaggtggtga gatgatcgag
    19741 agaatggaat tgggagaatt ttacaaagaa ctgcgcctgg ctagaaagct caagcagtca
    19801 gatgtggctt gtgctggtct aacagcctct cagttgtcca agtttgaact agggcagtct
    19861 atgttgtctg cagataagct catattagcc atccaaggga tcaatatgaa ttttgatgag
    19921 tttgggcaca agctcaacaa ctatcaagaa tctccacata tgcgatttgg tagaaaggtt
    19981 gtggatcgct ttgcccatca agatatagtt ggcttagaac aactattgga ggaagtcgag
    20041 caagaacaga tggcagagac ctatcgtcgt ttgaatgcca tcgtgattaa agatgccatc
    20101 cattccttag ataaaagcta tccgctagca gaggaggata gcgagttttt aaccacctat
    20161 ctctatgcta tcgagtcttg gacctggttt gaactctatc tcttttgcaa taccatgccc
    20221 ttcttgagca accaagattt gattttttta tcaacctctt tgcttgaaaa atctaaggaa
    20281 tttaaagagt tggtacataa tagactgtat atgaaaagtg gctttctgaa tattatatca
    20341 gagctcatgg agcgcaaact tttctcttac atcccaatct ttgaagccga gttggagagt
    20401 atgctccgtc cgtatgatgt ttttgagaaa gtgttgtggc agtttttaaa gaaaatgagt
    20461 atttttcttc aaaccaaggg aagcaaccaa aaagagattg gacactttat ccaatctctg
    20521 caagtattag aaaatccaca attaatagtc ctttttgaat tgcgtttgca gcaatacaaa
    20581 aagcttatcg attagttaga aatggcaaaa taataataat ctcagcaacg attttcaata
    20641 atgttaaaat ttgtttcttc atatttctcc actcctcatt agtagtaact ttattatacc
    20701 agagaagtaa tcaaattcac caaaatcgca aatctgaaat ttctataaga aaaaatatca
    20761 aatatgcgat tttctaaaat aagccaattt tcgtgttata ctgtacttgt aaagcacttg
    20821 aagcaaatcc taggtcgcag aagtggttta caaatgaaga taattgaagg agtgtaaaag
    20881 atgttaaatt tacaatttgc agaaacaatg gaattgacag aagctgagtt gcaagatgtt
    20941 agaggaggca acctcgtaaa ttctatggga ggtggtggaa gaagtggtat atctggttgg
    21001 ggcgtcccag gaatttaccc tggttggggc aatcaaggga tgagtcctaa tcgtggagct
    21061 tttgattgga ctatagattt agcagatgga ttgtttggcc gccgtagaag ataggctctt
    21121 ataggagata ataggatgaa gaaaatgaaa gaagtgaaat ttcacctagc aactggcttg
    21181 ttgattttga cttattacct catttttaat gtcacatcag acttagattt tatggttgct
    21241 ttgtctgata atatgtacta tgtgttccaa gttttattgg tacttattct gggaactata
    21301 gctacaattg cttttgtcaa aagtgaacat tggaaagagt gtggtcgttt ccagtttcgt
    21361 tggtcttacc tgggtgtttt ccttctttct tttttcttat tgttcgtgtg ggcaaatcta
    21421 acaacctata tctttcctcg tacccagaat ggaagtacag tcgtagaagt agccaccaat
    21481 ttaacaggaa ttagctattt tgttacgcga atactttata ctagtattat cgcacctgta
    21541 tcagaagagg ttgtttgtcg tggtcttttg atgacaagtt tatctaaagt taagagatac
    21601 tatcttgatg ttcttgtttc cgctgccata tttggcgcta tgcatgtttt gcagtatggt
    21661 tggataacga cagatttcat aaagtatttt ggaatgggct tgatattttg tatgatgttt
    21721 cgctacaccc gatccatcta ttgggctata gctctgcatg cttcatggaa tagtttctta
    21781 ctcattgtta ctttattggt atttggatat tagaaaggtg atatatgaaa aagataatct
    21841 cacaccgcta ctttattata gtttttctac tagttattgc tgaccagaag ttcagtgttc
    21901 tagttttacg cagcgacctt gttactgggc tatctgactt tgcctattat ctgtcggata
    21961 tgatgttgaa ttttcttgtg gttttatttg ctcttattgc tatgatttgg tcggggaaat
    22021 ggcagaaaat caatagtaga aagtttaaag gatcctatct tttctattcc ttcctagctc
    22081 tgcttgcttt tgttgtttgg aatttcgtta ccttttttct tttcccacct actcgaaatg
    22141 aaatttctta tcaacatgct gctccgactt ttacaggggc tacagcattt ttgatgtatt
    22201 ttttctatcc tgtgattgca ggtcccattt ttgaagagat aatccatcgg ggattggtga
    22261 tgacagctct ggaaaaagga aagaaatggg ggctagatgt acttggttct gctattttat
    22321 ttggggtctc gcacattagt aatcacggtt gggtcttgac agactttttc gtctatatgg
    22381 gtggcggact tatatttgca gtcttattta gaatgacaaa gtccatttat tggcctattg
    22441 ggctgcatat agtctacaac ggcattggtc agcttttgat gttactgtaa ttttggttgt
    22501 tagtagtatc gcggtctatt tctggggaaa gattcccatt tgaacttaag aaggagttgt
    22561 gatgaaagta tttcttcaaa atagagattt taggcaatta actatcaacc agtggatttc
    22621 aacgcttggg gatacgattt tttatctggc ctttctgaat tatgtggcag atgcgtcttt
    22681 tgcacctttg gcgattttac tcattacgat ttcagaaatc cttccccaaa ttttacaaat
    22741 ctttctggga gttttggcag attttcaaca tcatcgtgtc ttgaaataca cagtcattag
    22801 ttttgcaaaa tttttgcttt actctatcgt ttctttatca ctttcagggc agtctttctc
    22861 cttgttgcta gtagcattta tttgtctgat taacctcttg tctgacacat tgagttactt
    22921 ttcaggagcc atgctcactc cgattttcat tagaattatt gggcaagacc atctggcaga
    22981 agctattgga tttaaacagt caactgttag tttagtgaaa acaatcagta atattctagg
    23041 aggagtcttg ctagggattc tctccatcca gttcatttcc ttgctgaacg ctcttacctt
    23101 tttaatcgca tttttaggta tccttttcat aaaaactgac ctcttgaaag tagaaaaaac
    23161 gattaactat caagaaggac tctctgtaaa atccttttgc cagcatttgc tccaatcatc
    23221 gaaattgata tggaatatga ataaggtgct cttggttttg tttattatct ctactagtca
    23281 agcagtgata aatgttacag ttcctgtctc tactctattt ttgaggaatc aacccttttt
    23341 gaatttacaa acaggtcaat ctcttgcctt gctatccact tttgaactgt cagccctgat
    23401 tgtcggaagc cttgtaagtg gctatctgca acataccatt tccataaaaa cagctctcta
    23461 tgcctcactt gtcatccagt tgcttcttct agtaggattt gccacagttc gttttgactg
    23521 gattctcatc tttagtacct tggatgcctt tttcgcaggt gttctctctc ctagattgca
    23581 agaactcgtt tttaaacaaa tacctgagga gtcaatggga gcagttcaat cctctatcgg
    23641 tgccattacg gttgttttac ctagcttatt tacaatagct ttggtaacca ttgctactag
    23701 ctttggaact ctggcagtta gctttgtttt attgctattt cttctagttg cctttgttat
    23761 gcttctgaat attcgtgaaa gtatttagtg gagaatttct ataatatatg tttgagactg
    23821 gattgccagt ctttttatga tggtcaaaat caacagactt ttttctcttt tctgaatgtg
    23881 ttataataga ctgaatctaa aatagtacga aacaattgct aaaaaattta tagaaattaa
    23941 ttttactttc ccaatcgatt tgttctcatc ttatttcaat ctgctatata atagtccatg
    24001 ctgtggctgg attcttttca gtctacttat actcttcgaa actctcttca aaccacgtca
    24061 gcttcacttt gccgtaggta tggtt
//
LOCUS       DBERAE010000033        23786 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.33, whole genome shotgun sequence.
ACCESSION   DBERAE010000033 DBERAE010000000
VERSION     DBERAE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.33"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(127..576)
                     /locus_tag="ACL70N_001509"
     CDS             complement(127..576)
                     /locus_tag="ACL70N_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS0590286.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(578..1336)
                     /locus_tag="ACL70N_001510"
     CDS             complement(578..1336)
                     /locus_tag="ACL70N_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS0590287.1"
                     /translation="MEESKELNTVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1467..3446)
                     /gene="stkP"
                     /locus_tag="ACL70N_001511"
     CDS             complement(1467..3446)
                     /gene="stkP"
                     /locus_tag="ACL70N_001511"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGS0590288.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKTPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPIQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3443..4183)
                     /locus_tag="ACL70N_001512"
     CDS             complement(3443..4183)
                     /locus_tag="ACL70N_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGS0590289.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4198..5511)
                     /gene="rsmB"
                     /locus_tag="ACL70N_001513"
     CDS             complement(4198..5511)
                     /gene="rsmB"
                     /locus_tag="ACL70N_001513"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGS0590290.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5504..6439)
                     /gene="fmt"
                     /locus_tag="ACL70N_001514"
     CDS             complement(5504..6439)
                     /gene="fmt"
                     /locus_tag="ACL70N_001514"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGS0590291.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6452..8848)
                     /locus_tag="ACL70N_001515"
     CDS             complement(6452..8848)
                     /locus_tag="ACL70N_001515"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGS0590292.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYRHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(8914..9228)
                     /gene="rpoZ"
                     /locus_tag="ACL70N_001516"
     CDS             complement(8914..9228)
                     /gene="rpoZ"
                     /locus_tag="ACL70N_001516"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGS0590293.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9253..9879)
                     /gene="gmk"
                     /locus_tag="ACL70N_001517"
     CDS             complement(9253..9879)
                     /gene="gmk"
                     /locus_tag="ACL70N_001517"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGS0590294.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10009..11622)
                     /locus_tag="ACL70N_001518"
     CDS             complement(10009..11622)
                     /locus_tag="ACL70N_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGS0590295.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11891..12121)
                     /locus_tag="ACL70N_001519"
     CDS             complement(11891..12121)
                     /locus_tag="ACL70N_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGS0590296.1"
                     /translation="MEGVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            complement(12359..13456)
                     /locus_tag="ACL70N_001520"
     CDS             complement(12359..13456)
                     /locus_tag="ACL70N_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS0590297.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13466..14206)
                     /locus_tag="ACL70N_001521"
     CDS             complement(13466..14206)
                     /locus_tag="ACL70N_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0590298.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14315..14668)
                     /gene="rsfS"
                     /locus_tag="ACL70N_001522"
     CDS             complement(14315..14668)
                     /gene="rsfS"
                     /locus_tag="ACL70N_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGS0590299.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(14681..15181)
                     /locus_tag="ACL70N_001523"
     CDS             complement(14681..15181)
                     /locus_tag="ACL70N_001523"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS0590300.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15182..15775)
                     /gene="yqeK"
                     /locus_tag="ACL70N_001524"
     CDS             complement(15182..15775)
                     /gene="yqeK"
                     /locus_tag="ACL70N_001524"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGS0590301.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(15775..16404)
                     /locus_tag="ACL70N_001525"
     CDS             complement(15775..16404)
                     /locus_tag="ACL70N_001525"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGS0590302.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVAYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16456..16767)
                     /gene="yhbY"
                     /locus_tag="ACL70N_001526"
     CDS             complement(16456..16767)
                     /gene="yhbY"
                     /locus_tag="ACL70N_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGS0590303.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(16981..18087)
                     /gene="yqeH"
                     /locus_tag="ACL70N_001527"
     CDS             complement(16981..18087)
                     /gene="yqeH"
                     /locus_tag="ACL70N_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGS0590304.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPSLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(18090..18617)
                     /locus_tag="ACL70N_001528"
     CDS             complement(18090..18617)
                     /locus_tag="ACL70N_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGS0590305.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(18632..19540)
                     /locus_tag="ACL70N_001529"
     CDS             complement(18632..19540)
                     /locus_tag="ACL70N_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS0590306.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19597..20157)
                     /locus_tag="ACL70N_001530"
     CDS             complement(19597..20157)
                     /locus_tag="ACL70N_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGS0590307.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            20296..21507
                     /gene="sstT"
                     /locus_tag="ACL70N_001531"
                     /pseudo
     CDS             20296..21507
                     /gene="sstT"
                     /locus_tag="ACL70N_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21575..22528
                     /locus_tag="ACL70N_001532"
     CDS             21575..22528
                     /locus_tag="ACL70N_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS0590308.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            22671..23051
                     /locus_tag="ACL70N_001533"
     CDS             22671..23051
                     /locus_tag="ACL70N_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS0590309.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            23150..23371
                     /locus_tag="ACL70N_001534"
     CDS             23150..23371
                     /locus_tag="ACL70N_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS0590310.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            23388..23702
                     /gene="trxA"
                     /locus_tag="ACL70N_001535"
     CDS             23388..23702
                     /gene="trxA"
                     /locus_tag="ACL70N_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS0590311.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT         6456 a         5559 c         4705 g         7066 t
ORIGIN      
        1 aagttgcttt cgtggatacc aaaatcagcc gcaatttctt cataagtgcg gtattctcgc
       61 acatatagaa agcgttgtta atttatttat ctcatttttc agaaaattct ttcatttgtg
      121 taaagtctac gatactcgat gtgtttttat ataatgatac agtctgagaa tcactgttcc
      181 gctagccatt ccaatagaga ttaccaaagc caacatgaca accaaggtcg cacttgccag
      241 tgctttatta tagtcccctg tcacaaaaaa ggcagttgtt cggtaggaga gataacctgg
      301 aaccagcggt gccaaaatgg ccaagataaa gaccacagca ggtgtcttat aaagaatact
      361 taaaatctgg ctgacacaag aaccaataat ggctgcaatg aaggtagcta caatgacatt
      421 ggtcggctcc ttgagcaaga gatagattag ccagacagtc atgcccaaaa tccctccagg
      481 taagagcata gaccgttgca cattgagtac gattaaaaaa gtgataatgg caagaaaact
      541 tgctactgct tgtaataaaa aggttgttag tgtcatatta gttcatcaat accaaggcga
      601 cagaagttcc tgcccctaaa gcgagggtaa tgagcaggga ttcaaacatc ttactcatac
      661 cagagtttat gtggttggtc ataatatcac ggaccgcatt ggtcaaggca atacctggta
      721 caaacggcat gaccgcacca gctataatca aatctgccgt tgaaggaaaa cctgtgtagc
      781 gagcccaaaa ctgggcaatt atcccaaaga caaaggctcc agcaaaggct gtcacaaagg
      841 gaattcggat aaatttttcc acatagaggg aaaaggcaaa accaaataag gtcgccactc
      901 ctgccccaag tgcgtcgtag atatttccgc taaacataac tgaaaagaaa ggagcgctaa
      961 aggtcgcagc cagagttacc tgcaacttag tatagggaag gggttgagct tgcaaggccg
     1021 tcaattgctt aaaggctgtt tctaaatcaa tctgcccccc aaccagctga cgagaaatct
     1081 ggttcacatc gcagactttt tcgatgttat aagaagagga ggtcacgcgc ttcatgcgcg
     1141 aaatattggt attttcaata gagaaaaaga tagcggcagg catggcaagg acattgcaat
     1201 ccacaatccc ctgcgaatgc gcgattcgaa tcatggtatc ttctacacga tggatttctg
     1261 agccactttt aaggagaata gtccccgcta gcataatcac atcaatgacg gtatttaatt
     1321 cttttgattc ttccatgctt tcctcctttt atcaactccc tctattctat cacaaatccg
     1381 gactcaaaaa aaatctttgc catgaaatca tgacaaagat tgattactca ttttgattat
     1441 ccatctgctt gattatccat ctgcttttaa ggagtagctg aagttgtttt aggtttgtag
     1501 attgaaatct tgactctagt cttattgagg tctacctttt cacctgctct aggactttgt
     1561 tcaacaacca tgccttctgc actacctgca ggcgctgtcg tcacttctac aacttctata
     1621 ttagcttcct taatcccaac aatttgaatc aaattgttct tagtaaactc caagctggaa
     1681 ccaatgtaac tcggcatggc aacacttgta acttttttag ctactgtcaa gacaatttga
     1741 ataggtttac tcacatcata ggtcgttccg gcacctggac tttgtttcat aatcgttcct
     1801 ggttcgcttt cgctggactc ttcttcctct atcttaatca aattctcagg aaccttcttc
     1861 tgcttgagtt ctgagattac ttctgtagag ttccgtccaa tatagttccc taattgaatc
     1921 gtcgtagctt ttttagctac tgtcaaaaca atttgagttg ccttgctcaa gtcataggtc
     1981 gtaccttctg gtagactttg cttcaggacc gttccagcct cactctcatt ggactcttct
     2041 tcctcaattt taatcaaatt atctggaact tttttctctt ttaattccgc aatgacatca
     2101 gaggatttcc gaccgacata attactaatt tggaaggatt gcttgcctga tgagacaacc
     2161 aaattgattt tcgttccttc ttttcgacca gttccagcgc caggatctgt acggataatc
     2221 cgcccttctt ccaccttttc actagcctct gtcttctcct caccaatctc aaaattggct
     2281 tttttgagcg ttgccttggc ctctgcaact gtctgacctg ccacatctgg aatggcaatg
     2341 gttgcaggag ttctggatag tatccaaata agagaagctg ccaccaatac aaggctggcc
     2401 aacaaaatca ggtaacgcat cttaaatcta tgttttttcg gtgcttgtgg ttggtaagtt
     2461 tcctctgtca cagcctggct tggggttttg attgatttgt gttctgtctg cgcttgaacc
     2521 ttaggaatag atgtcaaggt actctgagaa accttcggca aggtcttggt atctgccttg
     2581 ctcgtttcat caaagattaa cttactttca tttctacgat tgtaggacaa gctactagac
     2641 aagtccacat acatctctga aaccgagcgg tagcgattgg tcaacttttt agcagttgcc
     2701 ttgataataa cattttctaa agcctgaggt acagatggat tttctgcaat aacggacggc
     2761 aggggtttct ggaaatgctg gagggcaatg gtcaccgcgc tatccccgtc ataagggata
     2821 tggcctgtca acatctcata gaaaataatc cccatagcat agatatcact ctgcacagtc
     2881 gccttcgaac cacgcgcctg ctctggggac aagtaatgaa ctgagcccaa catcgagtta
     2941 gtctgggtca gacttgtctc tgcaaaggct acagcaatcc caaagtctgt gacctttgca
     3001 gtcccatctg gtgtcaaaag gatattttga ggtttcaagt ccctgtgaac aattcctctg
     3061 gtatgggcca aacgcatggc taggaggatt tgtcccatga tacggactgc ttcttcatta
     3121 gaaagaggat aatgttcctt gatatagcgt ttgaggtcta gtccagcaac atactccatt
     3181 gcaagatact gttgaccgtc ttcctcacca atatctgtta tccgaacgat atgaggatgg
     3241 tctagatctg ccatagctct cgcttcacgc tgaaaacgag ctacagctat cgggtccgtc
     3301 tggtagttgg tcctcagaac cttcactgcc acttcttccc catctaagat taagtctttg
     3361 gctaggtaga catccgccat acctcctcga ccaatctgtt tgacaatccg atagcgtccg
     3421 gcaaaaatct tgccgatttg gatcattctg catcctcctc gttcatagaa acaagggcaa
     3481 ccgtaatgtt gtctaaacct cctgcattgt tagcaaaacg aacaagtgtc tccgttttat
     3541 ctgctaaagg aatatcactg gttacaatat cacgaatctc actgcctgaa atcatgttgg
     3601 tcaagccgtc actattgagc aagagatagt cacctgactc aaggataact gtcccaaaat
     3661 caggctgaat ttcatctttt tgcccaatag actgggtgat aatatttttt tgcggatgag
     3721 cttctgcctc ttctggtgtc aattgaccag ccttgagcaa ttcattaacc aaggaatgat
     3781 cgctcgtcaa ctgatggtat tcttctccac gaatcaagcc gatacgcgaa tcaccaatat
     3841 gagcatagat agcctgatta tcaataatag caaggacttc caaagtagtt cccatgcctc
     3901 tgtaagcttc atcctgacca agctggtgaa tcttttgatt ttcaatttct aggtaatggg
     3961 cgaaccattc acgcacttca ttgactgtat cgatctgggt atcaacccaa gctacaccca
     4021 ggtctgtgac cgccatttca ctagcgatat tccctgcacg atgacctccc atcccatcag
     4081 ctaaaataat catggtacgt ccagctctat tgacatagtg gttgacatag tcttggttat
     4141 ttgttcgttt ctgaccaaca tctgttaata atgaaatttc catgtgtcag ttccttccta
     4201 atccgatatc ttgcgaaatt gactgatgaa gaatccatca cttccataca attcaggtgt
     4261 aatgaggata cagccgtctt tcatgatatc cttacattca tgttctagtt ttacctgctc
     4321 gaactcggga tgactctcta aaaaggcctt aacgacttga aaattctcct ctgagacgat
     4381 agtgcaggtg ctataagtta ttataccacc tttgcctagt atttgacaaa cactacctaa
     4441 tatttctaac tgaatttcct gcaaggacgc gaaatctgcc gtttctttat tgtatttgat
     4501 atctggtttt cggcgcaaaa gaccgattcc tgaacaagga gcatccacca aaatcttatc
     4561 aaaggaatcc tggtcaaaaa actcatgcac ctttctggca tccaattttt gagtttgaac
     4621 ccgatcttca actcccagac gttgggcatt ttcttgaatt aaatccaact tgtggtcgta
     4681 caagtccaga gcagtaacct gacctgtcgt aagataagag gctatatggg ctgttttccc
     4741 acctggcgcc gcacaggcat caagcactcg ctcatcacct tgtaaatcaa gcgtcggagc
     4801 aaccagctga ctggactcgt cttggatggt aatggctcca tccgcaaaca aattatgccc
     4861 tgcaaaatgc ccctgctcct taaccagacc agtggttgct aaaagggaat cattcgcctc
     4921 caacaaggct tggatttcct cttttcgact taggtctgtt acacgaatac tggctttgtt
     4981 tcgcactaac aggctttcaa agatggcttt tgctctctcc tctccgtatt cttccttgag
     5041 tttggcaact agccaaactg ggagagaata ggcaatggag tcacgcttgt tttttcgctt
     5101 gatgctagca atatctggcc agccttcacg caagatacgg cgaaggacag cgttgaccaa
     5161 tttttcactg ccttttttac ggagtttggc taattccact gcttcattga ccacagcatg
     5221 atctggaatt ttgtccaaat agcggagttg gtaggcactc atgagaagaa ggacatagag
     5281 ccagctgtct aactggtctc tgtcttcgat aaagtgggat aggtaccatt ccagagtcag
     5341 tttacgggct accgttccat agactagctc ggtcactaag cccttgtctg ctgcagagag
     5401 ctgactcccc ttgaggtgtt tatttaaggc aatatttgaa tatgcttgat tcacaaaaac
     5461 atcctctagc actgctagag ctaaacttct agccgtttct actttagtca ccaaatcgtt
     5521 ctcctacagt caatgtacgt ccaactccat tgaggaagga agcaatgtcc atcttaggct
     5581 taccagctgg ctgcacttgt ttgagggata gagccccttc agccgttgcg acaatcaatt
     5641 ctttcttgcc gatagagaga atctcacctg gatttccctg accttctact ggtagggctt
     5701 cataaatctt aaagcggtcg cccttaagga aagtatgggc aacaggccag gggttcattc
     5761 cacgaatttg gttaaagagt tgacgattgg ttttgttcca gtccagtttt tcttcctttg
     5821 gctttatatt tggagagaag gtaacctgac tcgtatcctg cggttcaggt ttgatatcac
     5881 cagcaatata ggcaggcaga gtgtccaaaa gcaaatcaca accaactagc gccaattttt
     5941 caaacaaggt gccaacattg tcctcatctg tgatcggaat gctgcgacga gaaatcatat
     6001 ctcctgcatc catttcctta accatttcca tgatggtcac accagcttcc tcatcccctt
     6061 gaatcaaggc ataatggata ggcgcaccac cacggtgtct aggaaggagg gaggcatgaa
     6121 cgttgacagc aaagtccatg ctatcaagga gtttgcttgg gagaaactgc ccaaaagcag
     6181 cagtcacaat tccatctgct cctagcttca taagatcttc catctctgga cttccagata
     6241 atttttcagg ttggtagata gatagtcctg cttccttggc agcctgcttg actggggttt
     6301 cttggataac ttttttacga ccaacagcac ggtctggctg ggtcacaacg gctagaattt
     6361 cgtaacggtc atctgtcaaa agtcctttta agactgttgc tgaaaagtcg ggggtcccca
     6421 taaagattag ttttgtcata tcttctcctt cttataaaaa ttgctgcggc tcatggtcaa
     6481 tgctgagacg gagctcacta ttttcccgtt cttgagtcaa ggccaagacc tggttgaggg
     6541 tcggccccag ctcatcttct aaacggtatt taattaaaat ctggtaatga tagaggttgt
     6601 gggtacgggc aatcggtttt ggcgttggcc ccagaatggg actggtctct gacaagcctg
     6661 accgcaaaat gttcatgact tcataggcac gtttgaaaac ctcttcttct ttcttgtgag
     6721 aaagggtaat accaatcgtg aaatagtaag gtggatagcc gagttgtcgt ctgattccca
     6781 tttcataggc ataaaagcct tcgtaatctt gatccttggc aaatcgaata gcatagtgct
     6841 gcgaattgta ggactgtatc aagacttgac ctgctttttc agcccgacct gctcgacctg
     6901 ccacctgagt caagagctgg aaggttctct cagaagaacg gaaatcaggc agattcaagg
     6961 ccgtatccgc atttagaact ccgactaggg taacattggg aaaatccaaa ccctttgcaa
     7021 tcatctgagt accaagtaaa atatccgctt cccctcgccc aaactggtca agcaaggctt
     7081 ggtgactgcc tttctttcga gtcgtatcca catccatcct caaaatgcga gcttggggaa
     7141 agagttctgc tagctcatca taagccttct gagttcccgt cccatagtaa cgaatactgc
     7201 ggctcttaca gttaggacag acctgaggaa tatccttcga gaaaccacaa taatggcagt
     7261 tcatagtctt ggtatccata tgcaaggtca gagaaatatc gcagttggga caagtatcca
     7321 ccgtcccaca ctcccgacac atgacaaagc tagaataacc acggcgattg agcatgagaa
     7381 ccacctgctc ttttttaacc agacggtctt ggatagcctc tagcaaagga ggcgtaaagt
     7441 ttgacgtctc attttgtccg atatagtctc gaaagtcaat cacttgaacc tcagggattg
     7501 tagccaaagg attggcacgt tgggttagac gtaagtgtcg atagacgcct ttgccagcac
     7561 gtgcccggct ctctaagctc ggcgttgcag atccaagtac cagagttgct tgattatact
     7621 gagcccgtaa aatagctacc tctctggcat ggtaacgggg attgctgtcc tgcttataag
     7681 ccgcttcatg ctcttcatca ataatcatga cacccagatt tttcagagga gcaaagatag
     7741 cagatctggc accaacaaca acttgggcat cgccacgctc caccttacgc cattcatcat
     7801 acttttcgcc attggataat cctgagtgaa gaatggctac cttgtcccca aaacgtgcta
     7861 taaaacgctc ggtcatctga ggagtcaagg aaatctcagg taccagcaaa atagctgtct
     7921 tacccttatc cagggcacct tggataatct gcaagtaaac ctcggtcttc ccacttcctg
     7981 taatcccttg aagtagaaag ggaggttgag aactgccaat agaactcaca accgcatcac
     8041 gcgcctgtct ttgttctgga tttaactcca aaggtctact tgcttcaatt ccttcaaaat
     8101 aagcagccga gcgttgaact tccttttgga ctatggtaac agcaccttga tccacaaaga
     8161 agttgacttg ctctcgcgag taggactcta acaagctagc caaggaagcg ctctctggat
     8221 gagacagcag ataatctctc agttccaact ttttcttggc acgtgtagaa atctcaacac
     8281 cttctaattg ggcatggtca acctcatacc aagactgggt cttgaccttc ttttgatcga
     8341 ctgcctgata ttccagacca agcaggcctt ttctagtcaa acgcatcatt tcagcttgct
     8401 tggcaaggtc tagtgaagaa aaggctagcg aatcttctga accaaacagg cgtactcgtt
     8461 cttcctgact caagccttcc agaggataga gaatcttgtc atagctagaa ttcagaaacc
     8521 ctggaagcat ggccttgagg atagagattt tgtaggagaa gacagatttg cgtaactcct
     8581 cagccagcca gagttgttct ggcgtgagaa caggagaaaa atccagcacc tctgcaatat
     8641 cttttaaatc ttgctccatc tcttctccat ctgattggga cttcaaacca agaacaatcc
     8701 cttgaatcag gcgattcccc ttaccaaaag gcacatgaac ccgcatccca acttccagca
     8761 ttccctcaaa ttcctccgga atcctgtaac tatagggctg gtccgtctgc atcaagggca
     8821 catctacgat aatcttagct agggccatct tctcacctcc tccttgtcag tacattcttg
     8881 caatagaaaa aataagattg agtcccccca accttaaatt ttttcaccat cttctttttc
     8941 tttagcaatt tgctctttga ttttcttttc ttcttcttct ttgcggcgtt tttcttcttc
     9001 gatacggcga cgcactgctt cacgttttcc ttctggatct gggtgaattg taacgtttcc
     9061 tgattcgatt tcttctaaag cgcgaagagt tgatttttca gacttgaaac cttgagttgc
     9121 tggggcacct gcttccaatt cgtgggcacg ttttgcttcc aagattacga gtgaatattt
     9181 tgaaggaacc ttgtcgagca aggtatcaat agagggtttt aacatcattt gcttgtacct
     9241 attttctaaa ttttatcggg tagttggaga ttttggtaac atctcctgat agtgaccaat
     9301 gacacgatcc acacagaagt gttctgcttc aatcacacat ttgacacgtt cagcagctag
     9361 gggcacctga tcgttgacaa tcgcataatc atactcacgc atgagggcaa tttcttcctt
     9421 ggccttttcg attcgttggg caatcacttc tgcactatct gttccacgac ctaccaagcg
     9481 atcttgcaat tcatccaaat ctggtggtgt caggaagata aagacagcat ctggaacctt
     9541 tttcttgacc tgaagagcac cctgaacttc aatttcaagg aaaacatcga ttcccttgtc
     9601 caaggtttca ttgacatagg tcagaggagt tccatagtag ttgccgacat attctgcgta
     9661 ttccaacatc tgtccttgac gaatcagctc ttcaaattct tcacgagtac ggaagaaata
     9721 gtcaacaccg tccacttctc caggacgttg tgcgcgtgtc gtcatcgata cagaatattg
     9781 aaattggttt tcagaactct caaaaatctc tcttctaacc gttccttttc caacccctga
     9841 aggaccagaa aaaacgatta gtaagcctcg gtctgccatt atgtctcctt ttagtcaatc
     9901 tgtgaaataa catttctcta gaataatggc aaaaagccag attatccttt acagtctttc
     9961 tatctagtgt aacaaaaaag cagtaatttt tcaactgctc tttcttattt atttagcata
    10021 atctactgca cgaagctcgc gaatcacggt taccttgata tttcctggat aatcgagatt
    10081 gttttcaatt ttcttacgaa ctttgtgagc caagattgtg actttgtcgt ccttgatttt
    10141 tcctggattg accatgatac gaatttcacg tcctgcttga agggcaaagc tagtttgcac
    10201 tccttcaaag ccgttagcaa tttcttccaa atcatggaga cgcttgatgt agctttcaag
    10261 agactcacta cgagcacctg gacgggctgc gctcaaggca tctgctgcag cgacgataac
    10321 tgctatcacg ctctcagctt caacatctcc gtggtgacta gcaatcgtat tcaccacaac
    10381 tgggggttcc ttgtacttac gggccaattc cataccgatt tcaacgtggc taccttcaac
    10441 ctcatggtca atggctttcc cgatatcgtg aaggaatcca gcacgacggg caagagccgc
    10501 attttcacca agttcgctcg ccatgatacc agccaactta gcaacctcaa tcgaatggcg
    10561 caaaacattt tgtccatatg aagtacggaa ctgcaaacgt cccataatct tcatcaagtc
    10621 tggatgaagg tttggcgcac caatttcata ggcagcagcc tcaccgtatt cacgaatctt
    10681 attgtcaatc tcttgacggt ttttctcaac caactcttcg atacgagctg gatgtatacg
    10741 accatctttg agcaacattt ccatagtcat acgggcaatc tcacgacgaa tcggatcaaa
    10801 tcctgacaag gtcaccactt ctggtgtatc gtcgataatc acatcgaccc ctgtcaaact
    10861 ttcaaaggta cgaatgttac gaccttcacg accaataatg cgtcccttca tagtatcgtc
    10921 tggcagatga actgttgagt ttgttgactc cgctacatat tcaccagcga tacgttgcat
    10981 agcttgaacc aagatgtcct tggccatttt gtcagaacgt tccttgacct cttgctcagc
    11041 ttcgcgaatg cgactggcaa tctccctggt caagttttcc tctgtctgag ccaagataat
    11101 atctcgtgct tctgcctgag acagagcacc aatacgctct agttctgctt ctttttgtct
    11161 ttcgacttcc tctaattgct cttcacgcgc atcaaggttt ttcgctctat cagaaatact
    11221 ttgttctttt tgttcaagtg tttgttcttt actcgtcaaa ttgtcgtcct tacggtcaag
    11281 gctagtagct ctctctgtca aacgactttc gatttgtttg agttcttgac gttctgattt
    11341 gaattcagcg tccacttctt cacggtattt tctggcttct tctttggcct ccaatagtgc
    11401 ttctttttta agagacttgc tttcacgttt ggcttcatta acaagtaaat ccgcttcacg
    11461 ctcagcttgt ccacgtaaat tagttgcttc ttgttcagca tttaaaagca tcaactctgc
    11521 agcttcctga gatgatttca tcttagctga gatgctgaca tatccaatga ctaaaccaat
    11581 gatgacggca aaaacagcaa tcgcaagcga catgatttcc atgtttttac ctcattttat
    11641 tgttattccg aatgacatac attcttttac attctaccat aaaaaagtga ttttcacaaa
    11701 cctaaaatag aatatgtttt ggggaatttg gaacacattt accaaaataa acttgttgtt
    11761 tagaaatagt agtttagtag agacttgaga aaaagcctac tttgcagtag acttcctaat
    11821 gattatgcaa tacaagaagt ttgtttctaa caacagcaag atttcactca ggtattctct
    11881 gtaaattaga ctagtgtcct gcgcgaattt tatccattcc tcgcaaaacc ttgtctgata
    11941 actccttatt ttgggcgatt ctcagggttt cctgaatact gtcccattcg ctctttgaaa
    12001 gaactacaat gtcctcatct ggatttttat tgaccaccgt caaaggctca aattcatcat
    12061 ttaccttctt catgtaatcc tttaaatgat ttcggaatgt tgagtaaaga actccttcca
    12121 taaccatacc tcgttttagc tcttttccac tattatacac gaaaagaaag aaattgtcag
    12181 gaacctgtac aagattttct tttctatcta tttatactca atgaaaatca aagagcaaac
    12241 taggaaacta gcctcaggct gtacttgagt acggcaaagc gacgttgacg cgatttgaat
    12301 ttgattttcg aagagtatta ttcgtaaaaa atctcaaaaa gcctaccttt tagtagactt
    12361 agtttgtttc tattctaatc ggcactcttc caaaattttg ctctgctata cttggctttc
    12421 ctagttggta aatctggtct gctttttggg tcatagcatc ccaaggttct ttgccaattc
    12481 ggctgactag attgacctgt cctttcagag acttgagatg ttgcctgcct ttttcagtaa
    12541 atccaaggac atgaatggct tctggcaaga cattttccct agcctgcacc aaaatatagg
    12601 tcaataggcg tctgacacgc gccttggtgt aacgtttggt agtcactaac tcgaccaatt
    12661 cttccacaga ctgggctgtt ttaatagctt ctttaatgcg cacagccatt tcttgattga
    12721 cctgatagat ggtggttagg tcgggatttg acaagatttg atagcggagc aagggaaaat
    12781 agtcttccca gatcacctta ctggcctgct caaatagggc aacagaaggc ataaaacgtt
    12841 ctaagaaatc ttggtccttc tgatgttgac ggagggctgt cgccgaggca aagtccacat
    12901 ctttattcac agaatggtaa cctgccccct gacgctgaat cggatgcagc ttgatatttc
    12961 gtcctgcaac cgcctttgca taggccagag caagaacatg attgggggta ttacctgaaa
    13021 aatcaagacc agcaaattcc ttccacatag attgggtttt ctggggatag gaaagggaat
    13081 caggcagatt ttccacaaat ttctccatct cagcaccttt ctctgtgtat aagtcagcga
    13141 ttttctgata atctcgaact tcctctgtcc caaaaactag actatcaatg cccaagcgat
    13201 ccaagatatc cacagctcct tgaccaaaga aatcagctgc ctgaacactg actaaaaagg
    13261 gcaattccac taccaagtct gcgccatttt ccagcgccat ctgggccctt gtccacttat
    13321 ccacaatagc aggctctcca cgctgcatga aattccctga catggcaaca attttcagtc
    13381 cctctgcctg atccagcagg tatttatggc cattatgaaa aggattgaac tccgcgataa
    13441 tacctgtgat ggtcatgcta atctcctact tctgcgccac aaaaaaccaa cgggtgctag
    13501 tttctgttgg ttccttatcc tcaaagtctg catagagttt gaaggacttg aatccagcct
    13561 gttccagtaa gatatcatag gtcaagatct cataggtcct ctcctcatgt acttcatcgt
    13621 ggcgactaaa ggaaccgtca gcctccttga taaagaaagt cagctcatgc acgatggagt
    13681 gaggagcttc gtcctcatat gtatcccaaa gcatggcaaa atcttccgca ttttcatggt
    13741 aggaatagcc agggaatact tcatctgtct ggtaggtcga gtgcacgtca aagatgaaaa
    13801 ctccctcttc attcagcgca ttgtacacgt ccttaaagac gtcccctact tccacctcat
    13861 cctgcatata gcagatagag tccgaataac acgtgacaaa atcgtatttc cctgccttgg
    13921 acaaattcag catattacct tctataaaag caatcttttg cttggctgaa gttgctctct
    13981 tctccgcaat cttcaacata tccgcactca agtcaagtcc agtcacatca aaaccagcct
    14041 gagagaagcg cactgattga attcctgtcc cacaagccag ttccaagagt ttctttttct
    14101 ccttggtctt aggcaaatga cgcagagaaa aatttgtcca tttgtcgtat aaactatcgt
    14161 ccatgaccgc atcatagacc gccgcaaagg tttcataagt cgccataatc atgatactaa
    14221 gagctccatg gtaaacacca ctagcccttt acctttctat caatttttct aaaataagca
    14281 aagaaaccca gttgactaca actgagttca tcttctaagc aagagcttct gaaatatcta
    14341 ctgaattcgc ctcatgccat agcttctcta gattataatg ggcacgcatt tcttctgaaa
    14401 agatatgcac gacaacagca ccgaggtcca gtaagaccca gcctccagct gcatcgcctt
    14461 cgacatggct acctttaaag cccgcttgag ctactttttc acggatatta gctgcgatag
    14521 cgtccaactg acggctattc attgagctag tgatgacaaa gtagtccgtc acactagtca
    14581 aatcttgtac atcaagtgcg aggatatcct ccgcacgttt ctcatcagcc gctttcacga
    14641 ctagttctag taattctttt tcgttcattt aatcctcttt ttagaaaata tgtttgtaat
    14701 ctaggacatc tgcaaagcgc tcctcccaaa tgtcctcata aaattcatta atcgtttctg
    14761 ctggaatgtc atccccatca aaggttgtga cagcaccttc tggaacaata agctgatagc
    14821 catattcaaa ggcaaccttg acagaggtat ccacacaata ttctgtctgc ataccacata
    14881 aaactaattt ttcaatcccc tgcttatcca agtattcttt taagccagtt tctttgaaaa
    14941 tactgttata cttcttctga aagacctttt cagcaggttt tcgatttaaa agcgcagata
    15001 actgccaatc ttctgatgtt tgagcttcag agttctcaat atgttgaaca tagataattt
    15061 caatattctt gcttctagcc tggttttgta aataagaaat ttttcccaat agactttttg
    15121 tctggaaccc agtttctact aaaacattct gaacatcaat gattataaaa gccgtcttca
    15181 tttagttctc tttcaaatag tgcacaaagg cgttataggt ttcaagggtt tggggataga
    15241 tggggaatcc ctgatgagct agatactcca cggtacgagc tgtttcgtag gccaccgcct
    15301 tattgagcga tagacttgca atctcacgcg ccacatctac tccaggaaag gctcgattgt
    15361 gctcgatata gtctgcgacg tagatgacct tatctaggtc tgtcatttga ccagcaccga
    15421 ctgtatggac ttcaatggct cgcaggattt ctgaatcatg caaatccaaa tcttcctgaa
    15481 ttttgtaaat tccgaccata ccatgccaga cattattgcc ccagtttttg aggtcagggt
    15541 ctagctggta acggtcaatc aaggctagaa attcctgatc tgacaacttt ttagcatagt
    15601 catgaagaag acctgctaga cttgctttct caacatctac accaaagcgc tgagctaatt
    15661 ccatagcggc acgctccaca cctagacaat gggttagacg tttctcaggt agaagctctg
    15721 ccattttttc caacaaggcc tcacgggagc agttgatata gtcttgatag gacatcagta
    15781 gagcccctcc ttctcgatgt agtctagcac tggctgaggt aggagaaagt tgggtttccg
    15841 accttgggca aggaagtccc gcaccatgct ggacgagata tccatgagcg gtacgtccac
    15901 ccagataact ggataggaag tccctacctt gtagcgtgga cgctgaaccc ccacaaactg
    15961 aaccatgtca accagttcat caattcggta ccacttaggc agataggcaa ccatgtcggc
    16021 accgatgata aagtaataat ccgtatctgg attcttctct gtcaaaatct tcatggtatc
    16081 gtaggtgtag gaaataccct tgcgctccaa ctcaatggtt tcaatgacta ggccgtcaat
    16141 cccctcaatt gccaactcaa gcatcttgag acgatggtgt tcagggatgg tttccttttt
    16201 atcaacgtga ggaggttggt attcaggcat gagaagaact tgatccagtc ccaactgttg
    16261 ccgtacttga tccgcaacaa tgagatgggc attgtgaaca gggttaaaat tcccccctaa
    16321 aatcccaact tgtttgcgtt ttttctcctt gatttctggc tccaactcta ccttggtaaa
    16381 gggagtcaat agttcgattg tcataggcta gtccccttta tttctctata aaaacagtta
    16441 tttggagttt cggtcttaga tttctttgac tttcttagaa atcttgcgat tttctttctt
    16501 gctagattgt ttaaacaaaa tcaagatgcg tcctattttt tggactgtat ccacaccgat
    16561 ttcttcttcc aaaatttcag ctacttcgtg gatgttttca tctgtgtttt gtaagagagt
    16621 aaccttgatt aattcacgcg catcaagagc ttgacggacg ctggttttga tttggtcgtt
    16681 gagtccattt ttcccgattt ggatgatagg tttgagggtg tgtgcctggc tgttgaggaa
    16741 ggcacgttgt tttgatgtta atgacataat tttcttcctt gtttttggat agttatttta
    16801 ggtggtgagg gacggtcgga actaattttc caaagatttc atctttgaaa aatggatttc
    16861 ctgacctcac aattgagcct tggtctcaat tgtgcccctt gccaatctac agattggcaa
    16921 tcacaccacg gcaataacta tcgctatatg agctcacttt gttcgctcag cgattttgtt
    16981 ttaaataatt gcttttcgtg tgacgacggc gacgccttct ggtgcccaga cggcgacttt
    17041 tgctatgcct gttacacgaa tccagcctag gcctgagatg actaggtctg tcttatcttt
    17101 aatggtaaag acatgctgga ctagacttgg gaaatcttct ttttccttgc tatttggtgg
    17161 tgtcagaaga gttcccaggt gcttatcgta gaaagcacta gctccttcaa gcttgctacg
    17221 atggagtttg agttcattat caaagaaagc agtaaatcct tgcttttctc ctgctataaa
    17281 gtcaaagcgt cccaaaccac ctaaaaatag ggtttgctca ggattaagct gataggtctt
    17341 aggcttgatt tcctttttag gactgacata cttgaggttt ttggccgtca agtagtgagc
    17401 catctggtgg cggtggataa ttcccggcgt atcgtaaata taagatccgt cgtcaagcgg
    17461 aatctctatt ttgtccaagg ttgtccctgg gaagcgtgaa gtagtgatga cattctgatc
    17521 acccgtgatt tcttggataa tagcattgat tagagttgat tttccaacgt tggtcacacc
    17581 gaccacatag acatcgcggc ccttacggta gtgttcaatc ttgtcaatga cttccttaat
    17641 ggcatgttta ttttgtgctg aagttaggac cacatcgact ggacgaagac cttcttcatg
    17701 ggcacgtttc atgagccact ggctaatctt accagactta actgacttag gaaggatatc
    17761 ttttttattt cctaccaaga ggacatcatt gcccgagacg aaacgtggta aacctgggat
    17821 gacagatcca ttaaaatcaa agatatcaat aacattgacc actaaagcat cactgtctcc
    17881 cacctcgtgc aagagcttga ggaaatcatc gttcgtcaac tggacatctg tgatttcatt
    17941 gtagtggcgg agacggaaac agcgttggca atagacttcg ccagtctcca aacctttttc
    18001 aagtgccgac tggggggtaa aaccaagacc agctttatct gtcgtctgaa tggttgctcc
    18061 acaaccaata cagagaattt cttccatagt taaattcctt ttttatatgt aatcggtccg
    18121 tacttttcag tgatttttct cataacacga cgctcacgag ttcggttaat ctgcgttttg
    18181 attgagtcat gttggaccaa gggtttgact aaaattgacc gaatccctgc acggtgggct
    18241 gctcgtatat ctgtcatgag ctggtcacca accatgacca cttccttttt gtcatagtgg
    18301 aattccttca tagcacggtc aataccaaat gtgaagggct tcaaggccca gtaaacgtaa
    18361 tcaatcccaa atttctcaac tgctcgttga acgcgttttt tggtgttatt tgacactacg
    18421 ataatgccaa tacccgcgtc ccgaaggtca tgtagccatt gcttcatctc tggcgttcca
    18481 tcagggttgt tccaagcaat gagggtatta tccaaatcga ccaaaacagc cttgattccc
    18541 tgcgcctgca ggcttgggac tgtcagatca tagactgctt ccacagcaaa atctggtata
    18601 taattttcaa tcgccattct ggctcctttt cttaactttt tttcgcaatt ttccttagta
    18661 acaaggataa aacaatccac aaacctgcac tagccaaact gatatagagc caagcatggg
    18721 gctcatctgt taaaggtaag ggaacattca ttccgaaaaa gcctgtcacg actgccaaaa
    18781 cagctagcaa gactgaaatg atagtcaagg ttgtcaaatt gtcattcaga ttattgttta
    18841 gaatattgtt gtaagaggct gaaagctgct gtaaaatctg agagattagg tctgtcatgg
    18901 ataccagctg atgagcctca atcatggcat catcaaactg ttctctctca atctcatcaa
    18961 aactacgata caaggcatga ccttgaatat gctctaacaa aatccgattt tgtttggcag
    19021 ctgccgtcag ataaaccata ccagtctcca aatcagacag ggcaaagagg tttttcttgg
    19081 tagttcgctg gcgcaagagg tcattgacct catccctact cttgtccatc tgctcaatga
    19141 caggatagta ggcattgctg ataatttcca gactggcaaa gagaaactta taaatcgaaa
    19201 gcgtgtcatg gctctccaga taacgagtca tctgttcaat gacataggcg ttcttggtat
    19261 tactaatggt aatcaggcga cgatgctcga caataaaggt catgggaaaa gtctcatagt
    19321 aggccttgtc cttttttacg tctaggacat tatagataaa ggtaaccgtc ccactttcac
    19381 ggtggtagtc catgtgggcg cgctcgtttc tatccagtgc gtattcaatg gtttccttgt
    19441 ccaaaccgta aatttcagaa aggtcttcta gtttattcaa ctttcctagg tctaggtcta
    19501 tccaggtaca accattgccc aactgctttt ctaaaaccat cttttctcct tattaaactc
    19561 cctctattgt accacaaatt acttaaaata acaggtctag tctgtgcgtg agaaattgct
    19621 aacaactgtg atatttcggt tagggacaaa gtgaaggact tgctcctcgc tacgaagctg
    19681 tgtcgtacga attcccacac tgacaacctt acccgataca gtaatcggtc catttgtcag
    19741 aacgacctca tctcccacat ccagttgacg ttcaaagagg atgaaaaagc cattgatgac
    19801 atcagacaga aagccttggg ctcccatacc aatcgctacc ccagcaatac cagctccagc
    19861 cagcaaacta gaaactggca aacctaaaat cgacaaaatg cagtagagta aaaagaaata
    19921 tagcgtataa ttaaacacat tttctagtaa acgtgagatg gttttttggc gtccaacatc
    19981 atgacgagac atttttagag aaggtttgac aattctctgc accatggtat gaagcatttt
    20041 tttagcaata taaaatacaa tcaaaagcag taaaagagaa atgaccttgg ttagaatatt
    20101 ctcgataatg gttgtcacat ctagcttttc aatataagcc tgaataaatt tttgcatata
    20161 aaactccttt atttcattat accatatttt catcagtctc attctccata aatattcaaa
    20221 aaatagacag aaaattcttg attttgtcta tcatttatac tataatcata atcactacac
    20281 aaaaaggaga ttattatgaa aagaatcatt catgcttgga ataaggcaag ccttgtcaag
    20341 cgtatcttga ttggtatgct ttgtggggaa tcctaggact gacccttcct aatctctcag
    20401 ggattgggct actcggggat ttattcgttg gaggtctaaa agctgttgct cctatcctag
    20461 tctttgccct cgttgccaat gccctttccc aacatcaaaa gggacaagat agcaatatga
    20521 aaactgttgt tttcttgtat atcctatgat agggactttc gccgctgctc ttgtagctgt
    20581 actagcaagt ttcatcgtcc ctattgaaat taccctaaat agtgccaata ctgaaattgc
    20641 accaccagat ggggttgggc agatcctcag caacctcttg ctcaaactgg ttgacagccc
    20701 agtcaacgcg ccctgtttac tgctaactat attggaatct tatcttgggc agtcattttt
    20761 ggaatcgcta tgagagaagc cagtaaaaat agtaaagaat tgctaaaaac tatcgctgac
    20821 gtgacttcta aaattgtcga atggatcatc aatctggctc catttggaat ccttggtctt
    20881 gtttttaaaa ccatttctga caagggagtc ggaagccttg ccaactacgg tattttattg
    20941 gttccattag taacgactat gctttttgtt gcccctgtgg tcaacccttt gattgccttc
    21001 ttctttatga gacgcaatcc ttactctcta gtttggaact gcctccgtgt cagcggtgtg
    21061 acagcctttt tcactcgtag ttctgcgact aacattcctg tcaacatgaa actctgccat
    21121 gaccttggac tcaacccaga tacctattct gtttctatcc cactcggttc tactatcaat
    21181 atggctggag tagcgattac cattaacctt ttgacccttg ctgcagttaa cactcttgga
    21241 attcctgttg actttgccac agcctttgtc ctcagtgtgg tagcagctat ctcagcctgt
    21301 ggtgcttcag gtattgccgg aggttccctc cttcttatcc cagttgcttg tagccttttc
    21361 ggtatttcta acgatattgc catacaagtt gttggggttg gttttgtgat tggtgtcatc
    21421 caagactcat gtgaaacagc ccttaattct tctacagatg tcctctttac cgccgttgcc
    21481 gaatacgcag caacccgtaa aaaataactc atcaaggcaa gcctgctcat gtcttgtctt
    21541 ttacgctttt attctaactt attaggaaat tcttatgtct attagccaac gtacgaccaa
    21601 gctcatctta gctacctgtc ttgcctgcct gcttgcttat tttctcaatc tttcgtcagc
    21661 agtttcggct ggaattatcg ctctcttgag cctatctgat acgcgtagaa gtactttaaa
    21721 actggctcgc aatcgtcttt tttctatgct tctagctctg gctatcggtg ttctagcttt
    21781 tcacttgagc ggatttcata tctggagtct cggcctctat ctggccttct acgttccttt
    21841 agcctacaag atgggctggg aaattggcat cacaccaagc acggttttgg ttagccatct
    21901 cttggttcaa gagtcaacct ctccagacct cctagtcaac gaattccttc tctttgctat
    21961 tggtacagga tttgccttgc ttgttaatct ctatatgcct tcacgagaag aggaaatcca
    22021 gcactaccac acgctggtgg aagaaaagtt aaaagatatc ctccagcgct tcaaatacta
    22081 tttatccaga ggagacggac gcaaccgagc acagctggta gcagaattag acacgctttt
    22141 gaaagaagcc ctcagactgg tctatttgga tcactctgac cacctctttc accagaccga
    22201 ctaccatatc cactactttg agatgagaca gcgacaaagt cgtatcctga gaaacatggc
    22261 ccaacagatt aacacttgtc accttgccgc cagtgaaagc ctgatcttag cgcaactctt
    22321 ttcaaaaatt gcaggtcaac tgagccagac caatcctgct tctgatttgc tagatgaaat
    22381 tgaacgttat ctggaagtct tccggaaccg cagtctgccc aaaacaagag aagagtttga
    22441 aacccgcgcc acccttcttc aactcctacg tgaagccaaa accttcatcc aagtaaaagt
    22501 tgatttttac caaaaatata gacagtaaaa aataaaacca ctaaaaaaca gagcttgcca
    22561 gcattcttga aaagtagtat aattattgca tgcgcaatca tcttgtgacg cagagactgc
    22621 ccgttaatgg actttcttct atttatgact ctaaaaagaa aggagacact atgacctatt
    22681 tggaaaaatg gtttgacttc aatcggcgtc agaaagaaat tgaaagtctc ttggaagaga
    22741 ccattgccca acagagcgag caaagtctga ccttgaaaga gttctacctg ctctactatc
    22801 tggacttggc tgaagaaaaa tctctacgcc agattgacct gccagataag cttcatctga
    22861 gcccgagcgc agtttctagg atggtggctc gcttggaagc taaaaattgc ggtctactca
    22921 gtcgcatgtg ttgccatcaa gatagacgct ctagttttat ctgcctgaca aatgatgggc
    22981 aaaagacact ggcctcgcta caaaagactg tcgaagaaag cttggaagca ggtttggatt
    23041 tcttgattta agatgatttt aaaaaaagtt gcgtgcgcaa tcatttttct tgacattctc
    23101 ttttataagg agtaaaataa agttagcatt aaacaaagga gttttaaaca tgattgaaat
    23161 tacctatata gatgccagca agaacgaaag aactgtgact ttcgagtctt atgaagactt
    23221 tgaacgttcg caacaagctt gccttatcgg cgtcgcagac tactaccctg tccaaaaatt
    23281 aacttacaag ggtcataatt tggactacca tgggacttat ggagatatct tcttctatct
    23341 catgaaacaa gatttaagcc aatataacta aaaaaaggag aaatacaatg gcaaaagcaa
    23401 ttacagatgc aacattcgaa caagaaacaa aagacggttt ggtcttagta gacttctggg
    23461 caacttggtg tggtccatgt cgtatgcaag gtccaatctt ggacaaattg tctgaagaac
    23521 tttcagaaga tgtcttgaaa atcgttaaaa tggacgttga tgaaaatcca aacacagctc
    23581 gtgcttttgg aatcatgtct attccaactc ttctcttcaa aaaagacggc caagttgtca
    23641 aacaagttgc aggtgttcac acagcagaac aaatcaaggc catcattgct gaattgagct
    23701 aatcaaacga gagaccaagt actttctttg gtctcttttt tcttgccctt tgccattttt
    23761 caaaaaatat gctagactat agcaga
//
LOCUS       DBERAE010000034        22231 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.34, whole genome shotgun sequence.
ACCESSION   DBERAE010000034 DBERAE010000000
VERSION     DBERAE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.34"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="ACL70N_001536"
     CDS             complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="ACL70N_001536"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS0590312.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1420..2196
                     /gene="recX"
                     /locus_tag="ACL70N_001537"
     CDS             1420..2196
                     /gene="recX"
                     /locus_tag="ACL70N_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGS0590313.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2285..2818
                     /locus_tag="ACL70N_001538"
     CDS             2285..2818
                     /locus_tag="ACL70N_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGS0590314.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3176..3607)
                     /locus_tag="ACL70N_001539"
                     /pseudo
     CDS             complement(3176..3607)
                     /locus_tag="ACL70N_001539"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(3699..4031)
                     /locus_tag="ACL70N_001540"
     CDS             complement(3699..4031)
                     /locus_tag="ACL70N_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0590315.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(4044..4817)
                     /locus_tag="ACL70N_001541"
     CDS             complement(4044..4817)
                     /locus_tag="ACL70N_001541"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0590316.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(5264..6019)
                     /locus_tag="ACL70N_001542"
                     /pseudo
     CDS             complement(5264..6019)
                     /locus_tag="ACL70N_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(6157..7779)
                     /gene="groL"
                     /locus_tag="ACL70N_001543"
     CDS             complement(6157..7779)
                     /gene="groL"
                     /locus_tag="ACL70N_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGS0590317.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(7795..8079)
                     /gene="groES"
                     /locus_tag="ACL70N_001544"
     CDS             complement(7795..8079)
                     /gene="groES"
                     /locus_tag="ACL70N_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGS0590318.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(8349..8744)
                     /locus_tag="ACL70N_001545"
     CDS             complement(8349..8744)
                     /locus_tag="ACL70N_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS0590319.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(8822..9583)
                     /locus_tag="ACL70N_001546"
     CDS             complement(8822..9583)
                     /locus_tag="ACL70N_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGS0590320.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(9616..10242)
                     /gene="ytpR"
                     /locus_tag="ACL70N_001547"
     CDS             complement(9616..10242)
                     /gene="ytpR"
                     /locus_tag="ACL70N_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGS0590321.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(10258..10575)
                     /locus_tag="ACL70N_001548"
     CDS             complement(10258..10575)
                     /locus_tag="ACL70N_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGS0590322.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(10572..10871)
                     /locus_tag="ACL70N_001549"
     CDS             complement(10572..10871)
                     /locus_tag="ACL70N_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGS0590323.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(11069..11149)
                     /locus_tag="ACL70N_001550"
     CDS             complement(11069..11149)
                     /locus_tag="ACL70N_001550"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590324.1"
                     /translation="MASSGKMLRNTYTPDGYYVGNLGAWQ"
     gene            complement(11156..11347)
                     /locus_tag="ACL70N_001551"
     CDS             complement(11156..11347)
                     /locus_tag="ACL70N_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGS0590325.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            complement(11508..12182)
                     /locus_tag="ACL70N_001552"
     CDS             complement(11508..12182)
                     /locus_tag="ACL70N_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590326.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(12188..12634)
                     /locus_tag="ACL70N_001553"
     CDS             complement(12188..12634)
                     /locus_tag="ACL70N_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0590327.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(12748..13251)
                     /locus_tag="ACL70N_001554"
     CDS             complement(12748..13251)
                     /locus_tag="ACL70N_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS0590328.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFFLF"
     gene            complement(13248..13610)
                     /locus_tag="ACL70N_001555"
     CDS             complement(13248..13610)
                     /locus_tag="ACL70N_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGS0590329.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGEAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(13736..14707)
                     /locus_tag="ACL70N_001556"
     CDS             complement(13736..14707)
                     /locus_tag="ACL70N_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HGS0590330.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            complement(14714..15535)
                     /locus_tag="ACL70N_001557"
                     /pseudo
     CDS             complement(14714..15535)
                     /locus_tag="ACL70N_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(15552..16023)
                     /locus_tag="ACL70N_001558"
                     /pseudo
     CDS             complement(15552..16023)
                     /locus_tag="ACL70N_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(16147..16863)
                     /locus_tag="ACL70N_001559"
     CDS             complement(16147..16863)
                     /locus_tag="ACL70N_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0590331.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(17744..19159)
                     /gene="ply"
                     /locus_tag="ACL70N_001560"
     CDS             complement(17744..19159)
                     /gene="ply"
                     /locus_tag="ACL70N_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGS0590332.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(19170..19580)
                     /locus_tag="ACL70N_001561"
     CDS             complement(19170..19580)
                     /locus_tag="ACL70N_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590333.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(19573..20181)
                     /locus_tag="ACL70N_001562"
     CDS             complement(19573..20181)
                     /locus_tag="ACL70N_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590334.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(20194..20652)
                     /locus_tag="ACL70N_001563"
     CDS             complement(20194..20652)
                     /locus_tag="ACL70N_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGS0590335.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            20777..21176
                     /locus_tag="ACL70N_001564"
                     /pseudo
     CDS             20777..21176
                     /locus_tag="ACL70N_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21940..22200)
                     /locus_tag="ACL70N_001565"
     CDS             complement(21940..22200)
                     /locus_tag="ACL70N_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590336.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAIISSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         6730 a         4783 c         3850 g         6868 t
ORIGIN      
        1 cttttcaaac tttgtcaact acttttttaa acttttttta ttaattttac aacagcttca
       61 gttcgagctg tatgtgggaa catatcgacc gactggatat aatgaagatc atagacttct
      121 actaagcgta ccaaatcacg agccaaggtc gaaacattac aagaaatata aaccattttt
      181 tctggtacat aagtaagaat agtatctaat aacttatcat ccagacctgt acgtggtggg
      241 tcaacaatca aagcatctgc tcggtagcct tccttgtacc aacgaggaat aatctcttct
      301 gccgttccag cttcataatg agtattgtca aatcccattc ttttagcatt tcgcttggca
      361 tcttcaatag cttctggaat aatatccata cctctgagtg tttttacttt ctttgcaaag
      421 gcaaatccaa tcgttccaac tccacaataa gcgtcaatca aatggtcttc tttatcaaca
      481 tccagcgctt ttactgcttc gctatagagg acttctgttt gctcaggatt tagttgataa
      541 aaagctcgag gggatagtga aaattcataa ttgagtacac cttcttgaat actctcttgc
      601 ccccagataa tctctgtctt ttcaccatat atctcactgg ttttagctgt atttgtatta
      661 acagctactg tcacaacttc tgggaaatct ttaaccaact cttttaccaa ttgagttaaa
      721 ttaagctggc ggtttgtaac aataataatc tgaacctgtc cggtctttct cgcgcgtcgg
      781 accataatag tacggacacc tagaactttt ctctcatccg tgattggaat ctggtgataa
      841 gtaagtaatt ctgctaagcg attagcaatc acttgggttt ccttatcttg taccaggcag
      901 tctttcaact ctactaaata gtgagagttt tgtgcatata agcccgcctt gacctgattt
      961 ttaaattttc gagtctgaaa ttgtaactta gctctgtaat attttggttc ctgcattcca
     1021 atagttggac gaatttcata attttcatat cctgcaggag caaatttttt cagcgcttga
     1081 tgaagtaagt ccgtcttgaa ctccagctgc ttatcataat gcaggtgcat gatttggcag
     1141 cctccgcatt cattataaat agtacaagat ggcacaattc gaaatttaga cttcttgttg
     1201 accttcagta attttgcttc aacaaagttg cgtctaatag aagtaatctg acaatagata
     1261 tcttcgcctt tgagagctcc aggtacaaag actaatgttt tttggtaaaa gccgattccc
     1321 tcaccgttaa ttcccatgcg cttgattttt aatggtattt tttgtttcac tttcagattc
     1381 atacccctat cttatcacat tttgagttat aatagagcta tgaaaatcac aaaacttgaa
     1441 aagaaaaaaa gactctatct gatggagctt gataatggcg acaaatgcta tatcaccgaa
     1501 gatacaattg ttcgttttat gttatcgaga gataaggtga taagcgaaga ggaattgaaa
     1561 gagattcaag actttgctca attttcttat ggtaagaatc tggccctcta ccacttatcc
     1621 tttaaagcac gcactgaaaa agaagtcaga gaatatctga aaaaatacga tattgataaa
     1681 aacatcgttt ctcaagttat tgctaatctt aaagaagata agtggattaa tgatggtcag
     1741 tacgcttatg ctatcatcaa tgccaatcaa gtttcaggag acaagggacc ttatgtactg
     1801 actcagaaat tagcacaaaa aggaatttca aaatctacta tagaagaaat cttgaatgat
     1861 tttgattttt cggaagttgc tcaacgtgta gccaataaac tattgaaaaa atatgaggga
     1921 aaacttccag ctcgtgccct gcaagataag attatccaga acttgactaa caagggcttc
     1981 tcttattttg atgctaaaat tgcctttgac gaattggata gtcaagttga ccaagaaacg
     2041 actcaggaac tcatcttcaa ggaacttgat aagcaatata ctaagtatgc ccgaaagtat
     2101 gaaggatacg aactgaagca gcgtttaact caagttttag cacgaaaggg ctacgatttt
     2161 tcggatatag caagcgctct tagagaatat ctttaatatt tccaagtgaa attcacagat
     2221 tttaggtaat tttatggtac aatagtaaat gataaactta taaattgtag aaagttggtt
     2281 agttatgaag cttccaaaag aaggcgactt tattacaatt caaagttata agcatgatgg
     2341 gagtctccac cgaacttggc gggacaccat ggtactaaaa acaacagaaa acgccattat
     2401 tggtgtcaac gatcatacac ttgttaccga aagtgatggt cgtcgttggg tcactcgaga
     2461 accggctatt gtttactttc acaagaaata ttggtttaat atcattgcca tgattcgtga
     2521 taatggaact tcttactatt gcaatatggc tagcccctac tatctggatg aagaagcact
     2581 gaagtatatt gattacgatt tggatgttaa aatttttaca gatggggaaa aacgtctctt
     2641 ggacgttgaa gaatacgagc gtcacaaacg caaaatgaat tattctgatg acttggacta
     2701 tattttaaaa gaacatgtca aaattcttgt tgattggatt aacaatggac gtggtccttt
     2761 ctcagaagcc tatgtaaaca tttggtacaa gcgctatgta gaactaaaga atcggtaaag
     2821 ttgtcaaagg tcaggaacaa aatcctgacc ttgttttttt ggtagtataa aataaattgt
     2881 gtaaacacaa aaaggaataa atccattata gcagagttac aacacattac tagaaagaga
     2941 tttatgcaga attcgtaaaa tatataaaac aaatagatat actattattt tttaatgtct
     3001 ttattcctag taagtttaca acaaacttat atcgtttaat acaaaaaata cgaaaatgat
     3061 tagtataaaa aatacaggtc aacttcgtat caaaaacatt tttttgtatt tccacatagc
     3121 atcaatcatt tagtacaata ttttaaaaac aatatcttaa cagagaaaat gatatttaat
     3181 ctatcagctc atttaatcgt ttttgaaaat ataaagcaat acttttagat tcaataaact
     3241 caaaatattt tatgacattg tccatttgtt taattccaga ttctttagat tctgtcaggt
     3301 atattttata tccttctaca aatttgaatg tagatttttc aaaaactttt gtgtcatctt
     3361 ttaataattt ttgtaatttc atttcaaagt agtctgcata tattagatgt gaattttcaa
     3421 ggcaacagaa ccaaaaattt aaacaagctg acacaactaa atgtctattc ttgccgattt
     3481 tttcgtaata atgtgtacgc tctagtattt cttttccgac catgtaaata taatctattt
     3541 caaaaagatg atataaatta ccaatcagcg ttatctcata ggacttccat cgttccttct
     3601 ggaataaata gtcatatact aaatttagat catctctact aactacatga ttacaatcta
     3661 gctgatttca taatccctga accataattg tatttatttt atgagttttt cccactcttc
     3721 tcaaaaagtt tttgttgctt attttttatt acctccaatc ctttaatatt caaactataa
     3781 aaatttggag ataaattaac caaaaaatca tcacgctccg atcttttata atgttctaag
     3841 tgattacaaa aattctctat cgaaacattg atatttgata ataattcaaa aaatgttgaa
     3901 agagaaattt cattttctcc cctttcaaat ctagaaagtt gagattttga tatagaatca
     3961 gctgcagcat actctaaaga atatccgttt aattttctaa aatatcgaaa agcttctccg
     4021 taatttttca cactttcatt cccttaactt tcttttcgag cgataaacat accatattct
     4081 ttaggaatga tcaacatacc attattaaac tcactttcca atcttttacg tattatttcc
     4141 tcttctagtg aacctatttc tgaaattcct ttaaacgatt ggatgtattt aactaggtca
     4201 tctatactag ttacctgtaa ctcatcatca tagagtaatg tatcgacaga gttaaaatac
     4261 ctactcaggt accttttacc attttgtaaa gtaaacgttc tattttctaa atcttgatta
     4321 acctcatctt taaataaatt tgccaaataa tttacaactc cattttcacc aaatgtagca
     4381 cagtaaaaaa ttcctccggt ttttaagacc ctattcacct cagagagagc tttaggaata
     4441 tcattcacat gatgtagaag catattagca ataacaatat caaaagtttc attctcaaaa
     4501 gaaatctttt gaatatccat tatctcataa ttgacattgt ttctatttcc aatcactgac
     4561 ttcgttgatt ttaccatatc tttagaaaaa tctgtaacaa tcaactgctt cattttatct
     4621 atagaatcac tattactttt ccacaattct cctgtaccac atcccaattc tagaaccttt
     4681 acttcatcag tgatttggta gttagaaaat atccaattat taaatcccaa tttatttttt
     4741 gaatacttct tatgcaattc tactcgaata tcaagattat catgactttt atattgttca
     4801 attactttat caatcatttt aaatgacctc cactctataa tttggcatta tatcacaaga
     4861 ataaagatag tgttaaataa gttgtataaa tgcaaaaaag gaatattccg ttatagcaga
     4921 gttgtaacac atttctataa agaaatttat tcctacgact cagtttggca tgcttaactt
     4981 cctaactcaa aaacaaagca tcgattaatt tatccgttct tcttttgaaa cagatttgaa
     5041 ctgataattg ctcgttttaa tttaagaagc tcttttgagc aaaacttcat ttttttaaga
     5101 gtccaacaat ttctgtctat cgcttttcta ctagcaaaaa aaactacctt gaggcaagtt
     5161 ttcatttata tatctaattt cgtaatagta tagtaaaatg aaataaggac agtcaaatcg
     5221 atttctaaca atgttttaga agtaaaggtg tactattcta gtttcaatct actataaatt
     5281 tgatatgaga atagtctttc tcaacatcct tacccaacaa gaatgctgta gcgtccttct
     5341 taacttgaac caggtcaata ttctgggctt gggctgcata gacgcagcca caataacatt
     5401 gacgatagat atcatactcc tcacacatct ctactgaacg tttgtagcct tgatttttct
     5461 tgaaatcgtt gggaagatag tgggtcgtgt aaattttttg cacatcgatt ccgatgctgt
     5521 tgatggtttg agaattctta tgaggactga tggtcaaggc tgaaccaaag tagtcaaagc
     5581 ccaagtccat agccacttgc gctgttttat ccagtcggta gtcaaaacaa accttgcaac
     5641 ggtcgccacc ttcgggctcc tcctctagtc ccctaactag ttttcggtat taattgggtt
     5701 cgtagggagc ttctaggtac tgaaccgtat ttcctgtccg ctcattaaaa tcactaacaa
     5761 atttcttgat gacatagacc cgcttatggt attctacctt gggatggata ttagaattgg
     5821 caaaatagat ggtcacatct gcatacttgg tcaaatattc tagtgtatag gtactacaag
     5881 gggcacagca aacatgcacg agaatggttg gccgctgctc atttttctcc catgcttgta
     5941 ccattttctg catgacacgg tcataattaa tcttctgatt ggggggcatc ttgcacagaa
     6001 tttcttctac atcgatcatg ttcttctcct ttttctagtc ttattttatc atataagtta
     6061 ggagagctca aatcaattta gaagtgaata ttataaaaag aagggttagt cattccctcc
     6121 ttttgtgttt tttataagtt gttttctata gaaagcttac atcatcccgc ccatcatgct
     6181 tggatccatt gctggagctg gggctactgg ttctggttta ttggctacga ctgcttctgt
     6241 tgtcaaaatc aagctggcta cagatgctgc attttgtagg gctgaacgac tcactttaac
     6301 tggatcaatg ataccttgat caatcatgtt aacccactcg ccagttgctg cgttgaatcc
     6361 tataccaagc tcagcatttt tcaaacgatc gataacgata gatccttcaa atcctgcatt
     6421 gtgagcaatt tgacgaacag gttcttccaa agcacggaga acaatattac gtcctgttgc
     6481 ttcatctcct gtcaattcca aggtagcaac agctggaatc acattggcaa gagctgttcc
     6541 accacctgca acaatacctt cttcaacagc tgcacgagta gcgttgaggg catcttcaat
     6601 gcggagtttc atttctttca actcagtttc agttgcggct ccgaccttaa taaccgctac
     6661 accacctgac aatttggcca agcgttcttg caatttttca cggtcaaatt cagaagttgt
     6721 agtttcgatt tgagacttga taaccgcaac acggtgagaa atcgcttcag gatttcctgc
     6781 accttctaca ataaccgtgc tatctttgtc cacggtcact ctcgctgctt gaccaagagc
     6841 ttcaattgtc gcatctttca actcaagacc aaggtcttct gtgataactg ttccgcctgt
     6901 taagatggcg atatcttcaa gcatagcttt gcgacggtca ccaaaaccag gtgccttgac
     6961 tgctactacg ttgaaggttc cacgaatctt gttcaaaaca agagttggaa gagcctcgcc
     7021 atccacatca tccgcaataa tcaagagtgg acgattgctt tggagaatgc tttccaaaag
     7081 tggcaagatt tcttggatat tggaaatttt cttgtctgta atcaaaatgt acggattttc
     7141 aaggtcagcc accatttttt cgctatctgt caccatgtac tgtgaaaggt aaccacggtc
     7201 aaactgcatt ccttctacga cttcaagctc tgtttccata ccacgtgact cttcgatggt
     7261 gatgacaccg tctttgccaa ctttttccat tgcttcagag atgtactcac caactttttc
     7321 agaacgagaa gatacggctg caacttgagc gatagcttct ttattggcaa cagggatggc
     7381 gttgtttttc aaagcttcaa ctgctgcggc aactgctgtt tcaatcccac gacgaatacc
     7441 gattggattt gcacctgctg tgacgttttt gattccttca cggacgatag cttgggtcaa
     7501 gactgttgca gtcgtagttc cgtcacctgc gatatcattg gttttagaag ctacttctga
     7561 tactaactta gcacccatat tttcaaaatg gtcttccaat tcgatttctt tggcaatggt
     7621 cacaccgtca ttggtaatca agggtgaacc gaatgacttt tcaagaacga cattgcgacc
     7681 ttttggtccc aaggttactt taacagtgtc tgcaaggata tcgacaccac gaaccatggc
     7741 tgaacgggca tctgatgaaa atttaatttc ttttgacata cttactttct ccttctattc
     7801 ctcaatgatt gccaagatgt tagcttcgcc tacgatgatg tacttttcat cgccatcttt
     7861 gacatcaaga cctgcgtggg cttcaactaa gacacgatct ccagttttaa cacttggagc
     7921 aaccaagtca ccgttcaagg tacgaacacc ttgtccagta gccacaactt gagctgtttt
     7981 ggttttttct tgggctgagc ctgcaaggac aaagccccca acggtttgtt ctttttcttc
     8041 tatttttaag accacacggt cccctaatgg tttcaacatc tgatttcctc cataatgaga
     8101 tagatattat tagcactctt tgaacttgag tgctaattca taattctatt gtatcacttg
     8161 gtcagaaata gtcaagaaaa aagtctgact ttctcaagat aaaaagcctg agaccaactc
     8221 agacttttta atgtttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
     8281 gctgctcaaa gcattgcttt gatgttgtgg ataaagctaa cgtggtttga agagattttc
     8341 gaagagtatt aaaatggcaa ttcttcctct tccaagacca aatctgccaa atcttggcct
     8401 gcattatttt cacgcatggc acgttgagca cgactttcta agagttggaa tcctgtcaca
     8461 aggacttcgg ttacatagtt catctgacca tttttctcaa agcgacgggt acgcaattct
     8521 ccatcaacgg aaatgagact acctttggtt gcgtagcttg ccaaagtttc tgctagcctg
     8581 ccccatagga ccatattgac aaaatcagct tcacgttcac cgttttggtc tttgtaacga
     8641 cggttgacag cgatagttgc tcgcgctacc gacttgtcat tgttggtttt gtgcaattct
     8701 ggtgtagacg ttaaacgccc aatcaagata actttattat acatattttc ttcctcctac
     8761 ttatctattc gtaggaaatc aaaaaaagtt acagaaattt gtaacttttc gaggaaattt
     8821 cttatttttt atgaatcatg aaacctgtcg cctgttgatt ggccataatg gtcatatctg
     8881 taatctgaac acggcgaggc tgactggtca catagactac tgtgtctgca atatcctgag
     8941 cttgcaaggc ttctattcct tggtaaacgg acgcagcccg ctctttatca ccatgaaaac
     9001 gaacagttga gaaatctgtt tcgacaatcc caggctgaat ggttgtcacc ttgatatccg
     9061 ttgcgatggt atcaattcgc agtccatccg aaaaggtctt aaccgcagcc ttggtagctg
     9121 agtaaacagc ggcaccagca taggcgtaga ttcctgcggt tgaccccata ttgataatat
     9181 gaccttgatt gacttttatc attgctggca agaaacagcg agtaaccgcc atcagacctt
     9241 taacattggt atccaacatg gtcaacatat ccaactcctc atagtcttga tagggagcca
     9301 agtcaagagc cagtccggcg ttgttgacca agatatcaat cctccctatc gtttctagaa
     9361 tatcagagca aacagtcttc accatgacca tatccgtcac atctagtgga aaagtccaga
     9421 cggtttgatt tggaaagctt actgcaaact ccgacttgag gatttctaat ctgtctatcc
     9481 gtcgtcctgt tagaacgaca tcctcaccct gctccagata agcacgcgca atcgcttcac
     9541 cgattcctga ggttgctccc gtaatcacta cattttttgc catcttattt ccttctatca
     9601 gatgctgaca agttcctagg cagtccagtg tttcgctggg tcgaacggtg ttccgacaac
     9661 ttggtcttct gataattcaa gcaccccacg tttttgcgga gcatttggca aatgcaattc
     9721 acgaggacta cacatcatcc caaaactctt ttcaccacga agttcgcctg ggaaaatgaa
     9781 attccctttt ggcatcatgg caccaggaag agccacaatg gttttcaacc caacacgcgc
     9841 attaggtgct cctgcaacga tttgcactat cttgtcactt gcgactgcaa cttggcagat
     9901 gttgaggtgg tcactgtctg gatgagctac catctcgaca atttcaccaa caacaaactt
     9961 aggttcctta tcattaacaa tttcttctgt aaaaccttcc gcctgtaatt cttggttcaa
    10021 acgagcgact tgctcatctg ataaaaagac ttgaccgcgc tctgcaattt caaacaagct
    10081 cgaaacctca aaaatgttcc aagctactgt ttccccattt tctttgagga aaacacgggc
    10141 taccttgcct ttgcgttcca cattcagttt ggcatctccg ctatttttca cgatgaccat
    10201 aaggacatca ccgacatgtt ctttgttata cgtaaaaatc attgtttcct ttttctccta
    10261 tttcaatcct gctaaaaaat cgttaatttg ctccttactt ttacggtcgc gattgacaaa
    10321 acgaccgatt tccttgtcct tttctagaac aacaaggcta ggaattccgt aaacatccca
    10381 gagtttggcc aaatccatat actgatctcg gtccattcga ataaaggtga actctggatt
    10441 ggtctcttca atctctggta aggcaggata aatataacga caatcgccac accagtctgc
    10501 cacaaaaagg aagaccttct tgcccgcttt ttccactaaa gatgctaatt cttctaaact
    10561 tgctggctgt atcataagac ttcctcctca tagactaggt cttcattttc atagacaaag
    10621 gtataatgac ggccatcctc aaaaatgacg ccaccaagca agctctctag actgctttca
    10681 tagacttgaa catagagggt cgcaatttcc cccatgtctg aaaaatggtc tcgcacaatc
    10741 tctgtcaact cttcctgagt cttcatgagc ttacggtcat ctgcaacttt tttcgtagca
    10801 agagcaaggc ttccgatacc tagcagagcc aagcctgcca tccacatttt tttagctttc
    10861 ataccattca ttttaacaca aaaaaggctt caggacaaat gaggaagcag cagaaaagca
    10921 agtaaaaagc ctcttccttt aaggaaaagg acttcttata ctaagagcaa actagaaagc
    10981 tagccgcagg ctgctcaaaa cacggttttg aggttgtaga taaggcgacg ttgacgtggt
    11041 ttgaagagat tttcaaagag tattattctt attgccaggc acctaagttg ccaacgtagt
    11101 aaccatcagg tgtgtaggta ttgcgaagca tcttacctga tgaagccaga taatactact
    11161 tgccattgtc tttgacccaa tcattcgcaa tcatggcacc agaagaactt acataatacc
    11221 attctccctt gtcataaacc caagtactga ctttcatggt tcctgagcaa ttaaaggcaa
    11281 aaaaactgtc caatatcatt cgttttttaa aagcatttga cactacatca tctacgctgt
    11341 aggacataga tgcatcaaac gtaaaagcca aaatatcgaa aaatatacaa cttttaaagg
    11401 cagcatttca ttttttaaag tctaacaacc atagaactga aatcagagca aggcatcaat
    11461 ttcctactct tagtacgtct attttgatgg ttgaagtgaa gattttttta tttaacgtag
    11521 acaatttcca acttcccaaa agccacatct ccacggataa tcaaggtttt gctggttggg
    11581 gctacaggag cgtcagcctt agctgcacca aaggaggttt ctactttcaa atctacacgc
    11641 cagtgttgtg gaacatagac ggttgcattt ccgaaggcca cttcaatatt taaagttgca
    11701 aaatcaccta gcatctctgc attatcatag tagattttag catccccaaa agcgacttcc
    11761 acttggtcat ctacgagatc ttgatcttgc ttatagaagg tcccgctacc aaaagcgact
    11821 tccttatccg tgacgactgt ttttttccca ttgtaccacc attttttttc attccagaac
    11881 ttacttgaat gcgtcagata accaacacca agtaccacca agatgctagc ccaaataaga
    11941 gaatgattgg taactggtaa caagtcataa gcgtaatttg caatgatgat cgccagtaaa
    12001 cctgtaaaaa ctgccgaagt gagatgacgt ctaaggatgg actcaatgga cttataagca
    12061 aaaaaaacaa tacctagtaa aggccatatt ttaccatcca aagaaggaat tccaaaattc
    12121 ccttgcagca agatccaagc tgctaaaacc aataaaacaa taccaaatgc tttctttttc
    12181 atgtttttta cctcatgttt cttagatttt cttttaggag ggattggtaa tgccgtgaga
    12241 catgaacctc cttgtgcgtc tgataaaagg aaatggtgcc cgttcctgaa aaggacttgt
    12301 ccactgagta aatctgacgg atgtttgcga tcgttgactt ggaaactcga ttaaaatagc
    12361 gaggcaagat agactccaac tcatagagct tgaggcgaac ctcataagct tccttctggt
    12421 tatgagcgta gatcttgctc ccttctgttt caaagaagag aatttctgac aggtctagat
    12481 aatattcacc tgtccccttg taaaaagtca acctcggagc ctttgactct tgcaagagcc
    12541 gttgcaagtc tgcaatttca tctgtcaaag tgggggtctt gatgacaatt tcagtctcct
    12601 ctaaattgcc gtcaatctca attcgtaact tcatcacatc tcctttctga ctctactata
    12661 tcaaagctaa gttaggaata caagggcaaa aaagcaagtg gtcaatttga agcagtaagt
    12721 ggttgcaaga ccaacttaac ttacaggtca aaatagaaag aaaagcacac cccacgcaag
    12781 accacaaata taaccaacta ctacatcctt gggataatgt acaccaccta agactctcac
    12841 gagaccgagg agggctgaca agaccaacaa gataaagccc acagttagac tagcatgtaa
    12901 gcaagtcatg gagataatgg ttgctgaaaa gacatgacga ctgggcatag actgaccagg
    12961 actatctctg tcaagcaagg gtttaatatc ccattcctca taaggcctag gggcattgat
    13021 tttcttacga agaagggata aaatcacaaa acctgtagca gggataaaca cataaacccc
    13081 aacttgctga ccaagtccta gttgcaggta agtggtgact agcaagatca gatagaccag
    13141 gggcatggcg actgtcatca aacgattgaa actgcgtaat aggaataaaa gaattggacg
    13201 actagttagt ctggagctga tatttcgata ccattcttga taatttttca tttatgcttc
    13261 tcatactttt ctagaacttg ttgagatgtt ttccccttgg caagccaatc cactagcttg
    13321 tccaagcgac gtatttcctg catcagagga tcatcaattt cctcaatacg gacaccgcaa
    13381 atcttccctg taattgcaat tcgttcaggg acataatatg gtgcttgtcg aaaaaaatct
    13441 ccgtaagtaa catccctatc cagacaagca agaacgtcac tcacttcata ccctgtcaac
    13501 caactggtca cttggtgaac tgactctgcc tctccaccct ttcgctcaac ttttgcaatc
    13561 aaggctaaat agacagcagc aaatttcata ttgtataatt tctgactcat acttctctct
    13621 ttctatgtgt actagtataa ataagaaaaa gaaggccgtc aagccttctt ttgatttatt
    13681 cttctgcttc atcttctgta aattgactat tgtacaagtc agcgtagaag ccaccttaca
    13741 ccatcagttc ctcatagttg ccttgctcga tgatatttcc atctttcatg accaagatca
    13801 agtctgcatt tcggatggtt gacaagcggt gggcaatgac aaaggatgtg cgtccttcca
    13861 tcaaacggtc catggctttt tggatcaatt cctctgtccg tgtgtcaaca gaagaagtcg
    13921 cctcatccaa aatcaaaagc ggtgcatcct taagaagggc acgagcaata gtcaatagtt
    13981 gtttttgtcc tacagacaag gtcacggtgt catccaagat ggtatcatag ccatctggca
    14041 aggtcataat aaagtggtga attcccacag ccttactagc ttccatcatt cgttcatcac
    14101 taatccctat ttgattatag atgagattgt ctcgaatagt tccttcaaag agccaggtat
    14161 cctgcaagac cattgaaaag gcatcatgca cttctgaacg cgtcatagcc ttggtatcca
    14221 caccatcaat gcgaatactt cccttatcaa tctcatagaa tttcatcaaa agattgacaa
    14281 tggttgtctt accagcccca gtcggcccaa caatggcaac cctttgacca gcatgagctg
    14341 tcgcagagaa gtcatagtct tgaacattga caccgtccac cagaatttct cctgctgaca
    14401 cgtcgtagaa acgtggaatc agattgacca gagttgattt accagaacct attgacccaa
    14461 taaaggccac tgtttgacca gtttctgctt taaagctaac atgttcaata actgcctccg
    14521 aatttgccgc atagcggaag gtcacatcct taaactcgac ctgacctttg aagttttcat
    14581 cagtcagctg cacttgagca gggttttgga tagaagaatg caaatctaaa acttgattaa
    14641 tccgcttagc agagaccata gttcggggaa gaacgatgaa gagtgctccc atgagaagga
    14701 agtccatgac aacctacatg gcataagaca tgaaaacaat catgtcacta aagagaggca
    14761 gacgcgctat cggagcagcg tcgttaatca cataggcccc aatccagtaa atcgccacac
    14821 tcaaaccact tgaaatcccc atcatgatag gattcaaaat agccataaga cggttgacaa
    14881 acaaatttta acgggtcaat tcatcattta ctgctgcaaa tttttcattt tgataatcct
    14941 ctgcattgta ggcacgaacg acacgaatac ctgttaaact ctcacgagtg atactgttca
    15001 gtttatctgt cagcccctga atcaaggact gttttggaaa ggctagcgtc atcaaaacgg
    15061 tcgtcatcag gacgttgaca atcactgcca caagtacggc ccagagccag tattctgaat
    15121 gacctaaaat cttcccaata gcccagatag ccataattgg accacacgtt accacttgca
    15181 agtccatagt aatcaacatt tgaacttgag taatgtcatt ggtagtacgc atcaagaggc
    15241 taggaattga aaatttctta atctctgtct gcgagtaatc caaaactcgg ttaaaaatat
    15301 cacttctcag cctactagta taagaagccg ccactcggga tgcaaaaaat ccaactgcaa
    15361 ctacggacaa gaaggcaaga aagggcattc ccatcatcat gcttgccggc tgccacaact
    15421 catctaaatt agtttcttga ctacctagca aatccgtaat tttcgagata taggtcggca
    15481 cttccaactc tagatagacc gaaaagcaag taaagagaat ggctagtaaa atcatccccc
    15541 attcttttct actaattctt ttggttaatt tctttattct ctcctcctat tcccttgata
    15601 ttttgcctgt agttgaccga gaactttctc aaaaatcagt aattcatctt catcaatgtc
    15661 ttccatcaac tgcttgtcta tgcgttcaaa aaaagcctta acctgttgca tctgagaacg
    15721 tgctttgtcc gtcagacgaa caaacttagc ccgcttatca acaggactcg cctccaattc
    15781 caccaaacca ttttgcacta tacgcttaac cagattacta gcaacagact tggtaatatt
    15841 gagttcctgc tcgatatctt taatcaagac caagtcttga tttttctagc gattatccaa
    15901 aaaacgcaca acctgacctt gcggcccacc cataaattca atgccgcaac gtttggcttc
    15961 cttttgcacc atcaggtaaa tttgatgacc aaaacgctta aagactaaca tcggtttatc
    16021 cataatctcc cccttctaaa taaaaatagt tctctggaga ataattaaat ttctatgaga
    16081 actattttct tgattaaaaa aatcccaagt gattttctca cttaggatca tgttctatag
    16141 gttaaattaa aacccatcta cgttcgtata aatcttttgg acgtcttcgt cgtcttcaag
    16201 aacgctgtaa agtttttcaa aggtttcaag gtcttcgcct gacaattcca cttctgactg
    16261 aggaatcatt tccaattcag tcacttggaa ttcttcaata ccagactcac ggagagcaac
    16321 gatagccttg tgaaggtcag ttggcgctgt gtaaactgtg attgtacctt cttgtgcttc
    16381 tacgtcatcc acatccacat ccgcttcgag caattgctca aagactgcgt ccgcatcttc
    16441 acctccaaat acaataacac ctttgttgtc aaaaaggtaa gaaacagaac ctgaagcgcc
    16501 catgtttccg ccgtttttac caaaggctgc acggacattg gctgctgtac ggttaacgtt
    16561 agaagtcaaa gtatccacaa ttagcataga gccatttggc ccaaaacctt cgtaacgtcc
    16621 ttctgtaaag gtttcgtctg tgtttccttt ggctttatca atcgctttat cgataatgtg
    16681 ttttggcact tgggcttgtt tagcacggtc gataacgaat ttcaaagctg agtttgattc
    16741 tggatctgga tcaccttttt tagctgctac atagatttct acaccaaatt ttgcatatac
    16801 tttagagtta gctccatctt tagccgtttt cttggctacg atattggccc atttacgtcc
    16861 cattaggaat ctcctttttt cacattttaa tctttcttat tataacacaa gtttttttga
    16921 ttttcactag aggaaatgga ttttattagc aaatcaagct aggatagcac tttacctgct
    16981 aagatggtct tgcctttcta tctttatcaa cagacactca tccacattca aaaaacaaac
    17041 tagaccatta tctgcaaata gaaagtttca gccaagtttg acaaagtcag ctcaaattac
    17101 tgtttgaagt ttgtagatat aagcgacaaa aacaatcata ctgcaccttt tgttgacagt
    17161 ctactccaga catatcatag ttcaagtaaa tactttgaaa ttcaacagtt cttataggcg
    17221 ctattgtatt ctaagaaatc aatagaagag tttctaagca aacctctaat actcaataaa
    17281 aatcaaaaag caaactagaa agctagccgc aggttgctca aaacactgtt ttgaggttgc
    17341 ggataggact gacctggttt gaagagattt tcgaagagta taatttacgt gttcccaaga
    17401 tggagaaatt agactagtac actggcactt ctaaaccatt gctagcaatt gatttgttca
    17461 tatttaattt cattttttcc ataaatgggt attagatata aacagcaaaa tatttccgat
    17521 acgtgtcatt cttgaatttc caatcatcta aaacaagtaa aggataatca atcccctgta
    17581 tatcaaggaa ttggctaccc tttttacttt tttacacatt ctgtttgata gattcatttt
    17641 aacatcacga gcatactcca atggaaatcg ctaggcaaga gataaacttt cagatattcg
    17701 cagagagctc atcgcctctt tttgtcgcaa acattcttct ctcctaatca ttttctacct
    17761 tatcctctac ctgaggatag agagttgttc cccaaataga aatcgtccgc ttacgcacta
    17821 gtggcaaatc ggttttttca taaaccgtac gccaccattc ccaggcaagc ccggtacact
    17881 ctctaatttt gacagagaga ttacgaacat tcccttttaa aggaatacta gtggtaaagt
    17941 gagccgtcaa atcctgccca tttctgtccc aagccttagg agtcaagact tccttacctt
    18001 gatgatcata ggataattca tcccaagtaa tataatattg ggcaacatag gcaccactat
    18061 gatccagcag taaatctccg tttctgtaag ctgtaacctt agtctcaaca tagtctgtac
    18121 tattttgaaa ggtcgcaact acattgtcac gtaaaaaaga agttgtatag gaaatcggca
    18181 agcctggatg atctgctgta aagcgactgc cttcttgaat caagtcctct accatatcca
    18241 ccttgcctgt tacaactcgg gcacccgaac ttgggtcgcc ccctaaaata accgccttca
    18301 cttctgtatt gtccaaaatc tgcttccact ctgtctgagg agctaccttg actcctttta
    18361 tcaaagcttc aaaagcagcc tctacttcat cactcttact cgtggtttcc aacttgagat
    18421 agacttggcg cccataagca acactcgaaa tatagaccaa aggacgctct gcagaaattc
    18481 ctctctgttt taaatcctct accgttacag tatcttgaaa cacatctcct ggatttttaa
    18541 cagcatctac gctgactgta taataaatct gcttaaaatt aacaatctga atctgctttt
    18601 cgcctgaatg gacagagtta aaatcaatat caagagaatt ccctgtcttt tcaaagtcag
    18661 aaccaaactt gaccttgagt tgttccatgc tgtgagccgt gattttttca tactgcattc
    18721 tagctgggac attattgacc tgaccataat cttgatgcca cttagccaac aaatcgttta
    18781 ccgctccgcg aacacttgaa ttgctggggt cttccacttg gagaaagcta tcgctacttg
    18841 ccaaaccagg caaatcaata ctataagtca tcggagcacg atcgaccgca agaagagtgg
    18901 gattattctc taacaaggtc tcatccacta cgagaagtgc tccaggatag aggcgactgt
    18961 cgttggtagc tgttacagaa atatcacttg tatttgtcga caagctccgc ttctttcttt
    19021 cgataacaac aaactcatcg ggtagctgat taccctcttt gatgaaacga ttttcaatac
    19081 tttctccctg atgggtcaag agtttctttt tatcgtaatt catagctagt ataaagtcat
    19141 ttactgcttt atttgccatc ttatacctcc taataagttc ctggattgag ttgcataaac
    19201 tcagacttgt tcagcgaaat cagccgtggt tggactaagt gatccaaaat ttcctcgtac
    19261 aattcttctg agacattgcg tcgccgtctg gctagataag aagtcggaat aaccgtatta
    19321 tccaacataa ataccttatc taagtcaatc aaggttggtc ttgtaaaagg attacgagct
    19381 agatccggct cttctatcat aaagttcttg accaaacgtc tggtcaagag agctggtttg
    19441 aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc tgttgtcaat acagatatac
    19501 atatgattct tcacagccaa atcgctacta atagtcggaa aaggcaaata aagagctaca
    19561 acatctcctc tcttaatcaa gcaagagcac ccccttttct cctaatgtaa catagacagg
    19621 attgaccaag tcttctgatt gactcagaat ttccaaagtt tgagtttggc gcgctgtcaa
    19681 tttagtagca tcttgtctct tcaatacaaa atgcttgtcg ccaataacct tgacaatata
    19741 atccttctcc aaagctgact ggtaaatcca catcagatgt tgtctgtcct gagaactcaa
    19801 gagagaagga ttttcaagcc tcccgatagt ctgataaaaa tcaaaaacag gagctaactc
    19861 ctgccaatct gattggctag ttgtcaaggc tagaaaaagg gctttgcgag ctgatacttc
    19921 ttggttagcc ttgagagtta ctttcccctc caagtttttt agaaatcggg aaactccaga
    19981 aagcaaattt ttctctaact gcgagaaata aaaacctttc gttcccagac ataagtcttt
    20041 catgtcgctt tctctagcaa ataagagctc aaacatttga tagtaaaaga aaaatatctg
    20101 gcactgggtc gcgctcatct tttccttatc ggcttctttt tttaaccaga gcaagggcga
    20161 caggtagctg gattgagaca tttcctctac ctcctactct tttttaactg gagcatctgc
    20221 actagctgcc acttcttttg actggatact ttcccactgg ttaatctcct ctgagataag
    20281 accttcgcat gtcttgacaa atagggcaaa agccttggtc tttcctgcat atttctccgt
    20341 ttggcattga tagaggaatt tttctttctc caggagttgc gcagtttttt ggtaagaaat
    20401 ccaattttcc tttgcattat acaaattgat aatcccctca cacagcaagc cgagactgga
    20461 taaggcaacc gaaatcaaac ggtagcgatc acctggcata ggaatagcac aaaagacagc
    20521 tatgaggaaa cctgccacga tttctgttat ttttaatacc ttatagcgcc tacgatgttg
    20581 aacgcttttc tttaaaaaat gagctatctg tacgtctaat cgctctgtca ggtacatttc
    20641 ttctggcgtc atattcgtaa ctcctttcat ttactttgat aaccatagta taacatattt
    20701 gaatatcaaa gtatagtaaa aactggacta taacttatta gactccctgc gaaacaaaat
    20761 atggtatagt agttctatga attatgaagc aagtaaacaa ttaactgata cacgatttaa
    20821 gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg ttagctgtat taaaaacagc
    20881 ttatcaaaaa agtcggacaa gctggtaaaa tcttggctga cagtaattat caagggctca
    20941 tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag ccactaacag
    21001 ttgaagataa agtctataac catgcgctat ctaaggagag aagcaaggtt gagaacatct
    21061 ttgccaaagt aaaaacgttt aaaatgtttt caacaacctg tcgaaatcat cgtaaacgct
    21121 tcggattacg aatgaatttg agtgctggta ttatcaatca tgaactagga ttctagtttt
    21181 gcaggaagtc tattatatat atgcacagac atatgaaatc tttttgatac agccttcttt
    21241 ttacatagag agacagcagt tatgatatat ttatccattc acaacatctt ctgtaccaat
    21301 actacaatat tggtacattt tgattacaca atcgtttcaa aaaatatgat ggaagcctga
    21361 gtattttata gtaattccct tcctatcaac tagatcaacc agttgagtgt tgaatgttga
    21421 aacaccctag cctcagcaaa ggactatgat cagcatttcc tagccaatag gacgctccaa
    21481 atcacctatt ctaagtccat cactagcttg gtcagtaaga tacagactgc aaggcaagac
    21541 tgacgtggtt gatgagattt tggaagagta ttacaatcat agattcacca gtagacttga
    21601 ccgcagattt aactatagta gattgaaact agaatagtac acttctgctt ctaaaacatt
    21661 gttagaaatc gatttgactg tcctgatcaa tttgtcctgt tctcgtttca ttttactata
    21721 ctaaaaaacc acctgaaaca aatcaagtga ctagaggata aaaacaaaga ctgggcaaaa
    21781 agttttgaaa agcaaaaaac gcataatatc aggtcttgaa aaaccttgat actatacgtt
    21841 tgattgtggg aagattgact tcattttctc ctgaaattga agttttttct agtttccaga
    21901 tatagacgaa ttcaatatag ccatctcgct acaattattt taaccatcga gaaaattttt
    21961 cagaatttca aaaatttcat tttgatccaa tgaaatgtca tcattttgaa gaatagttga
    22021 cttcacaggc tctaattcta tcacaaagcg gtgcatgtct gcttttaccg cactacttga
    22081 tattatagcc gataactttt catctcctag caaggaagct gtcaaacggg taatgtcatt
    22141 caaatgcttt ttaatggact tacttaaatc ttgagcacct gtagcagagc gctctctcat
    22201 atccagccaa gctttagcct taaaaataat t
//
LOCUS       DBERAE010000035        21698 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.35, whole genome shotgun sequence.
ACCESSION   DBERAE010000035 DBERAE010000000
VERSION     DBERAE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.35"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1952)
                     /locus_tag="ACL70N_001566"
     CDS             complement(<1..1952)
                     /locus_tag="ACL70N_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HGS0590337.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKPRVRRNSPEIKAKGRVKNYEEANIELSKYMTDLY
                     KLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFAD
                     LLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGG
                     QAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDG
                     AKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKA
                     KLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKK
                     EKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQN
                     TPQVPEAPKSPEVPKVSDTPKAPDTP"
     gene            complement(2031..2558)
                     /locus_tag="ACL70N_001567"
     CDS             complement(2031..2558)
                     /locus_tag="ACL70N_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGS0590338.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2641..3972)
                     /gene="hk06"
                     /locus_tag="ACL70N_001568"
     CDS             complement(2641..3972)
                     /gene="hk06"
                     /locus_tag="ACL70N_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGS0590339.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3969..4622)
                     /gene="rr06"
                     /locus_tag="ACL70N_001569"
     CDS             complement(3969..4622)
                     /gene="rr06"
                     /locus_tag="ACL70N_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGS0590340.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(4943..7375)
                     /locus_tag="ACL70N_001570"
     CDS             complement(4943..7375)
                     /locus_tag="ACL70N_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS0590341.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7377..7835)
                     /locus_tag="ACL70N_001571"
     CDS             complement(7377..7835)
                     /locus_tag="ACL70N_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGS0590342.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(7958..8683)
                     /locus_tag="ACL70N_001572"
     CDS             complement(7958..8683)
                     /locus_tag="ACL70N_001572"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590343.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            complement(8683..9690)
                     /locus_tag="ACL70N_001573"
     CDS             complement(8683..9690)
                     /locus_tag="ACL70N_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0590344.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9729..10487)
                     /locus_tag="ACL70N_001574"
     CDS             complement(9729..10487)
                     /locus_tag="ACL70N_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590345.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(10450..10740)
                     /locus_tag="ACL70N_001575"
     CDS             complement(10450..10740)
                     /locus_tag="ACL70N_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGS0590346.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10811..10913)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10996..12342)
                     /gene="cbpD"
                     /locus_tag="ACL70N_001576"
     CDS             complement(10996..12342)
                     /gene="cbpD"
                     /locus_tag="ACL70N_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGS0590347.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(12431..12697)
                     /locus_tag="ACL70N_001577"
     CDS             complement(12431..12697)
                     /locus_tag="ACL70N_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGS0590348.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(12699..14051)
                     /gene="dnaB"
                     /locus_tag="ACL70N_001578"
     CDS             complement(12699..14051)
                     /gene="dnaB"
                     /locus_tag="ACL70N_001578"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGS0590349.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(14094..14546)
                     /gene="rplI"
                     /locus_tag="ACL70N_001579"
     CDS             complement(14094..14546)
                     /gene="rplI"
                     /locus_tag="ACL70N_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGS0590350.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14543..16516)
                     /locus_tag="ACL70N_001580"
     CDS             complement(14543..16516)
                     /locus_tag="ACL70N_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGS0590351.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQIIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16652..17200)
                     /gene="raiA"
                     /locus_tag="ACL70N_001581"
     CDS             complement(16652..17200)
                     /gene="raiA"
                     /locus_tag="ACL70N_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGS0590352.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(17280..17942)
                     /locus_tag="ACL70N_001582"
     CDS             complement(17280..17942)
                     /locus_tag="ACL70N_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGS0590353.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(17939..19237)
                     /locus_tag="ACL70N_001583"
     CDS             complement(17939..19237)
                     /locus_tag="ACL70N_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0590354.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19293..19928
                     /locus_tag="ACL70N_001584"
     CDS             19293..19928
                     /locus_tag="ACL70N_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGS0590355.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            20213..21133
                     /gene="cysK"
                     /locus_tag="ACL70N_001585"
     CDS             20213..21133
                     /gene="cysK"
                     /locus_tag="ACL70N_001585"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGS0590356.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(21372..21698)
                     /locus_tag="ACL70N_001586"
                     /pseudo
     CDS             complement(21372..21698)
                     /locus_tag="ACL70N_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_068988785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6343 a         4902 c         3591 g         6862 t
ORIGIN      
        1 tgcggtgtgt ccggagcctt tggtgtatct gaaacctttg gtacctctgg gctctttggt
       61 gcttctggaa cctgcggtgt gttctgaatt aagccttttt ggaatttagt aacaaccgta
      121 tccatgtctg caaatacctt gtggactgta ttctcaattt ctactttggt atttacatta
      181 tcaatttcag aaagtgcttg ctttttaagt ttatcaaggt ccttaataag agcaacaatc
      241 tgatgatgtt tttctttctt cagatgatgt ttctttatat catctaaaat cttgctcatg
      301 tatgttgcta tagcaagttt agctttttct ttctcctgat taatatctgg tacgcttggt
      361 ttctcaccct ctggttgtgg ttttggctct gggttttccg gctgtggttt aacctctggt
      421 accaatttcg ctttagcttc tttcaattta gacatggcat cgttcaattt ggttaattgc
      481 attgccaatt catccattgt cactgctgtc tgtgatagaa gcttcttgct tttgtcaaca
      541 acttctttcg cataagttct agtctcatta taggcttttc cagcttctcc tgtgagttta
      601 gccccatctg gaacagtctt tgtttcatcg tctagtttgt tcaaggcttc ttggaattga
      661 cgaatcaagt cttgtaactt tttcttttca gcttcggtcg ccttttgtcc tggactttgg
      721 gaagttgatg gaggtgtttg cgtcaccggt ggtacaacca ttgaaccacc tgcttgtcct
      781 cctggttggg gtgctggttg gttttctttt tctctatttt ggtgagtcac gataagagac
      841 tctatttttc cttctgcttc ctttcgcaag tcttctaccg attttttatc tgaagcatcc
      901 tctaattttg tcttgtattc ttccacaacc ttcttagcat ccataagaag atctgcaaac
      961 caaaaaacag atggatccag cttcgttaaa cgagttacca tataggtaga cagagtttct
     1021 ttcgctttgt ctatcgtttc cttaagttct ctcgaatcgc ctacttgcgg agaatttctt
     1081 cgcactctag attttggcgt ttctttggtt gagttatcta atttatacaa atcagtcata
     1141 tatttagaaa gttcaatatt agcctcttca taatttttga ctctgccctt agcttttatt
     1201 tccggagaat ttcttcgcac tctaggtttt ggcgtttctt tggttgagtt atctaattta
     1261 tacaaatacg ttttttcaat atctgattta attttttcta gttttttaac attactttta
     1321 gcagcttcta ctttagattt agcagcatta attttctcag tatcttgagg tatttgaact
     1381 tgagcttgtg caaactcaag ctcaagctct gccttggcga cccctacttc tgcttccgca
     1441 atttccagtt cgattgtttt gtaagtattg gttgggtagt tacggcgatc ttcttctttt
     1501 tgagctttgg cttttttctc agcttctgct accttttttc ctgatttcaa tgtatctttt
     1561 ttaaactgct caaaagctgc ggttaactct tcttttgttt cttttgtttt taacgtcaac
     1621 tcagcttccg acttctcttt taatccatac aaatacttcg ttttaattct gctcaacttt
     1681 ttgttgaagt cgacattttg ggtatgttga acttttttca aatttttatt gacatccttc
     1741 aatatacttt gtagatgcga ctcgacttca tcagcatact tcttcgatat atcttgccca
     1801 ctagatgtaa ccgtgaggtt attcttactc ctaacccctt ctgcatggac tactcctcct
     1861 aagaacaagc tggcaactac tacactagct actccaatac taaatttacg aattgaataa
     1921 tgtacttttc tttcgctttt tgatgcaaac atgtttattt ccttctatat tttttcttta
     1981 accttactat atcacttcaa tatgaactgt atatgagtcg aattttgtat ttatctcttt
     2041 atgcttccat ttgggattat aacttcatgt aatagctttt cctcttcagc tattcgtcga
     2101 tacaaaataa ctgcataaac tggaaaaact aaaacaaaag tcatataggc atgactcaac
     2161 aaggtcaagc caatcaactc aggtaaaata tttaaaaagt aattagggtg ttttactgtc
     2221 ctaaacaaga tatgatctac atatttgtga ttattgacaa gcataagctt cactgtccaa
     2281 atatctccca acaagtgaat caccaacatc aacatcagca tagaaaaaat aagcaagact
     2341 aaaccaacca tgcccatgcc atcaaaaatt gtcttgtgca ccattgcctc aaccaagcaa
     2401 gagagataaa aaacaatatg agccatagtt aatcgttttg tattctcaac tccaaattct
     2461 ttcccgccat tgctaaggat tcgtttctca ttctctatcg aacgctttaa aaaaatcaat
     2521 cgaataaaga atgttactaa aataatcgct aataccatat tagtatcctt tcttttatct
     2581 acacaaagaa taacacactt atgttaaccc tatatgaact ttaataaaaa actaatctgt
     2641 ctacaagcta atcttaaatt ccataccgtg ttcataaggg agaaaactat aatccatttg
     2701 atagctttct aaaatattat tcacaatgta aagacccaaa ccggaacttt catccttatc
     2761 tgtcacgatt tgagaatgat aaaatatatc aaataaatgt tctagttctt ggtcacttag
     2821 aggcgcacat gtatttttga tagagagata gccatcttgc tcggatatga ttacgcgccc
     2881 atttttatct gaatatttaa ttgcattact aatcaggttt gtcaaaacct tatccaatgc
     2941 cctaagactc atgacgactc tggtagcatc tgtcaattga ttttcaattg taacacctat
     3001 tgaatgagct aattcttgat aacgtgataa aatatctact aaaactggct taacagtcaa
     3061 agtctcacga cactctgtcc actcttggaa tttagaagac tccagtactt cttccaataa
     3121 gtggctcatc tggtcaatct tatttatact ctttgcaata tattttggat gatctttgta
     3181 atctccaata ttatgctgca tattctctag gataattcta agactggcta aaggggtttt
     3241 caactcatgt gatgctccgc ggacaaagga aaccttttga ttttgcaatt ttacaatttg
     3301 ctcattacga ctttccaact cataaataac cttcaacaag tgctcataca taccattaat
     3361 ctgttttcca acttcaccaa cttcatcttt cctactttca tcaaaacgaa tattgtcatc
     3421 caaatcttgc attttactag tcacttctga aatgtaaaaa agaggattga gcaagcgttt
     3481 agtataaaaa taagaaaaaa caaaggaaaa agcaattgta accaaaaatg tatatgggag
     3541 atacaaaagc aaaatattct ttgcttcttt gtagacatcc accccgtgaa caaattgcac
     3601 tgttacctgt ttaccatctg ctgtactaac agacatatct aacatcacga tataatttga
     3661 tagctttcca tctttaatat ccaagtcatg cacaagaggg agccgcttat ctacaatatc
     3721 tcttttaagg tgagcagata tggtcaagga ctttgaataa gactggagta agcttggaat
     3781 ttcatcagat gtcttagtct ttaaatactc cgtaaacact cttgcgctct cattaaactt
     3841 ttccccctcc agttgaatat aataaaaagg aaaggtcaaa taaatagcta tatgaatgac
     3901 tagaccaaca ccacctagaa ttgcaaaact tcttaaaaag gacttggtta ataatttagg
     3961 attttttatc ataaactaat cttataccca acatttttca cagtcacgat acaatctaaa
     4021 gctaattttt tgcgaagagt acgaatatag acatcaacga ccctatcaca aggtaaatca
     4081 gctacatctt ttgaaatttc ttccaatatc tgctctctac ttaaaacttg atttttatgc
     4141 tgaatcaaac actttagtac cagtaattcc tttggtttga gatcaatttc ttcattttta
     4201 taatgtgctt tgtaagaggt aaaatccact gttacatcct gatatcgcca aatatcctct
     4261 atgacgtagt aacgtctgat aagcgcctta atacgcttga caagcagtac caaagaaaaa
     4321 ggttttgtca catgatcatc agcatagaga tcaaatacct gtgactgagt aatttcatct
     4381 cccagagcac tcaagacgat gacaggaata tcgtgctttt gattgatttc ttttaacact
     4441 tcaaaaccac tcttcctagg catcattaaa tccagtacca tgagatggat agggagatct
     4501 tgaaattttt ccaagacctc ttgtccatcc ttagccataa tgacatgata accctcttct
     4561 gtcagaaatg ctgcaattcc ttctctaatc atttcctcgt catctgcaac taaaatgttc
     4621 atctctctcc ctttctacta ccagaactcc atacatctat ttcctgtatg ctatttgaaa
     4681 atttcctacc agcctatcat ctatgataat agaatggatt tcatttatcc gctacttttt
     4741 gtcaacaaca acgtcaatac aagaaaatca ttcatcttgc agcttatact cttcgaaaat
     4801 ctcttcaaac cacgtcagct ctatctgcaa cctcaaaaca gtgttttgag caacctgcgg
     4861 ctagctgcct agtttgctct ttgattttca ttgagtttca ctccactgtg acttatggtc
     4921 agatgctggt acttttattc ttttatgcaa tatcaaattt taactggcct gctttgacac
     4981 caatcttaag tgtgctgcct gccactaaat ctcccttgag aagaagttct gccaacttgt
     5041 cctccacttc tgtttgcagg gttctgcgaa gtgggcgagc tcccatctct gggtcatatc
     5101 cttgatttgc taacaatttc agagctgaag cttgtaattt caagtcaatg cctttttcag
     5161 ccaaacttgc cactaaaggc ttgaccataa tcttcaccac ttcctgcata tgatcactag
     5221 ataggctatg gaagaccacc ttctcatcaa tacggttgat gaattccggt ctataagctt
     5281 ttttcagttc ttcaaacatg cgtttttcca tattttcctg gtcaaaacga atatccttag
     5341 ccccaaaacc aacagtctta tcatcacgaa gggcagtcgc acctaggttc gatgtcataa
     5401 tgataatggt atttgaaaaa tcgaccttgc gtcccttgct atctgtcaag acaccgtcat
     5461 ccagaacctg caagagaaca ttaaagatat ctgggtgagc cttctctacc tcatcaaaga
     5521 ggagaacgga atagggttta ttgcgaacct tctctgtcaa ctccccacct tcttcgtaac
     5581 ccacatagcc tggaggagct ccatttagac ggctggctgc gaatttctcc atatactcac
     5641 tcatatcaaa gcggataagg gctgattcgt catcaaagag aacttctgcc aaagccttgg
     5701 ccaactcggt cttaccgaca cctgtgggtc ctaggaacat aaaggaaccg atcggacgct
     5761 tgtgactgcg aattcctgac tgattacggc gaatcgcacg actaatactt gaaacagctt
     5821 gatcttgacc gataacccgt ttatggagtt ctgcttcaag atttagatat ttcttagcgt
     5881 cagtctgagt cagcttttga actgggattc ctgacaagcg actcaaggtg gtcaaaatat
     5941 cagactctgt caccaagtct ttgtagacag gtacttcctc ttcttttgcg attagctggg
     6001 ctgcctgttt ccacttgcca tccatcaggg ccttgtcagc tggactcaaa tctgaatcgt
     6061 ctgcttttac atgctttgcc ttattttgca ctgttgctgc tgcttcgtcc aagaggtcga
     6121 tagcagagtc tggcaagtga cgactggtta aataacgatg agccatctta accgctgttt
     6181 caaccgcttc atctgtgatt tgtacacggt gatgtttctc ataagtcgcc ttcaaacctt
     6241 gtaaaatagt catactatct gccacacttg gttcttcaat cgtcacttta gcgaaacgac
     6301 gagaaagtgc cgcatctttt tcgatatgtt tttgatattc ttcctgagta gtggcaccaa
     6361 ccgttctcaa agttccacgc gccaaggctg gtttcaagat attggccgca tccagagtcg
     6421 aatcaatccc gctaccagaa cccatgatgg tgtggagttc atcgataaag aggatgactt
     6481 ggccatcttc ttcaatatcc ttgatgatat tattcatgcg ttcttcaaag tcaccacgga
     6541 agcgtgtccc tgcaacgaca ttcatcaaat caagttctaa cacgcgcatc ttagccattt
     6601 ccgcaggcac gtcaccacta gcaatacgct gggcaagacc aagggccaga gctgttttcc
     6661 cgacaccagc atccccaacc aagacagggt tgttcttagt cttacggctc aagatttgaa
     6721 tcatacgtga gatttccttg tcccgaccga tgactggttc taacttgcca gaacgcgctt
     6781 gctctgtcaa atcatgcgta tagtcctcga gaccaccact aggagtctgc ggcatgccca
     6841 tcatattggc catagaattt tgcttgtcag ctactgtacg atggcgttgg cgtaaagcct
     6901 tgagatcttc acgagtccag cctgcacgtt cttctaaatt tcgacgaagg gcagcaatct
     6961 tgacctgatc tttcttgtct tcataagaaa aaccagccct ctccaagata cgagtcgcca
     7021 aggcattgcc atcatgcaaa atcgcataga ggacgtgctc tgtccctagt accttagcat
     7081 ggaccactga cgctacatac tctgcttcat caaaaagaac ctgcaaacga cgggagaacg
     7141 gcaattccgt aaaggtttca tcctggctat agtccgtttc agtcagttcc aaagccacct
     7201 cttctaaacg gtccatctca tacggataat catttaaagt tgcccctgct acactataac
     7261 tgtgattaga catggcaatc aacaagtgcc acgactctag ataacgagct ccaaaatgtc
     7321 cagcaaccat gtaggcactt tcgatacatt cattcaatgc ttttgaatag ttcatcttac
     7381 ttcccttttc tatctacctc ttgtatgacc tgacgtagca tgtttgctcg aacaactgga
     7441 gcttcttctc ctaaaacgcg atccaaagct actgattcta gcaaattcat ctcctgcttg
     7501 gtcatcaatt cctgctcaac caaaagctgg agaatatcct cataaatttc ttgactgact
     7561 cgctcaccaa tcgagtaaag cagatcccgg agcatttcat gatgactaga aaactcaatc
     7621 cgtcctatac gaatgtagcc tccgccacca cgcttacttt caaccaagta gcctctactt
     7681 tccgtaaagc gtgtcttgat cacgtagtta atctgactag gaacaacctg aaaggtatct
     7741 gccaactgac tccgttgcaa ctccacgata ccagattgat ctaaaatcgc cttgatgtag
     7801 gcctcaatat gatccgatgt atttttaaat ctcataacaa acccacctct ctctttaaac
     7861 cttgaccttg tttgactatt ataccgaaat tttctcattt ttaaaagaaa aagggcgctg
     7921 gtaaaggata atcttcacca actccctatt tttctactta ttctaagcct aattctgcca
     7981 agatttgacg tttgtaggca atcttttgga cttccttgtc ctcatcttca gaccaatcta
     8041 gtttaatttc tgaaacaatc tgcccagggc gatttttcaa gatatagatg cggtcgctga
     8101 gattgagggc ctcctcaata ctatgcgtga tgatcagagt tgttagctgc aactgtttgt
     8161 gaatctcaag ataccaagcg tggagttcca tctttgtcat ctcatccaag gcgctaaagg
     8221 cctcatctaa gagaaagagc ttgtgcccaa aaaggtaggt ccggagtaag gctacacgct
     8281 ggcgcatccc accgctaagt tcatgaggat acttgtctct tacagctgtc agctggaagg
     8341 tcgcaagaat tttatccgct cgggaaatag cttctgcctt atccaccttt tgaatcaaga
     8401 ggggcagaat gatatttcca agcaccgtct tgtgctccaa gagcagatcc ttttgcaaca
     8461 tataactcac gcgccccttg ggattttctt caccatcaag gacaattctc cctgactgaa
     8521 cttctaaaat cccagcgatt agattaaaga gggtggtctt tccaacacca cttgggccta
     8581 ggatggaaac cacttcgcct gaagtcacct gtagattgat atcctctaaa atcctctcct
     8641 gaccataggc ataactgacg tgctctagtc taatttctgt cattatttca caaattcgtt
     8701 ggtgaagcct ttgtctgtca agtcttcttt aaggatacca ttttctttat cccatttgta
     8761 gaaagcattc cagcgagctg cgtcaaattg accccatttt tccttgtcgc ttgcgtattc
     8821 ttttgacaag tatttttgag attcgatgac aaagtcacgt ttttccttga gttcaggtgc
     8881 attcttgatg agaatatctg cagcttcttc tggatgttcc atggcatatt ggtagccttt
     8941 tttgatggct tggatgactt tgcgagcttc ttctttgtta tctttcagat agtcgttgtt
     9001 tgcgatgata actggtgaat agtagtcaaa ctccttgaca tagtctttca agtacatgaa
     9061 gttagcatct acaccttgag atttagcaag gataccatcc caaccgtagt aaatccaagc
     9121 agtatcaaag acgccattgg caatcggtgt gattgagttt gagtcgttat ttggtacttt
     9181 ttcaaccttc tcaaagtctc caccttgaga ttctaccaag gttttcaaca tagcaagttc
     9241 agttgggtca ttccatgtcc catatttctt accaaccaag tcttttggac tgcttacatt
     9301 atcagattta cgagagatga ttcctgatgt attgtgttca acaatagctg caacggcagt
     9361 gattcctgct cctttttcca atttcttagc catgtagtct tggaaataca ctgcaaatgg
     9421 tgcctttccg ttgataacca agtcagaaga actttcttct ggtggcaatt tcaaatcaac
     9481 atccactcca gcttctttga aataaccttt ttccttggca acataaagcc ctgtgtggtt
     9541 ggtatttggt gtccagtcta ggataaagtc aaccttctta agttctgcct ctttgttgtc
     9601 tttagaagca gttccttgac cacaggccac aagcacaaca gctacaagag ctgttacaag
     9661 cgttaaaaac actttccatg ttttcttcat tttgatttcc tcttttcttt ttcagaaaca
     9721 ttctaattct acgaacgttt ccatttaatc acatattttt cactgatatc gaccagcttc
     9781 atacccaaaa gactgataat cgacaccaga ataataatgg caaacatggt atcatactga
     9841 aacaattttt tagactgaat catataaaca ccaagacctt caaaacctcc caaccactca
     9901 gataccacag ttgtgataaa ggcgtaggag acactgaccc tcagacctgc ataaaagtaa
     9961 ggcaggctaa ctgggatttt aaaatgccac aggatttgcc aaggcttggc ccgcatcaga
    10021 ctaaacaagg tcagcatatc cttgtcgcaa tgcctaaaac cgtccaaaat actaacgatg
    10081 atgggaaagg ttgtcgttaa gataatcaag acaatcttgg gcaaaatccc ataacctagc
    10141 cacaagacca ggataggagc tatggcaatg gtcggaatgg tctgaatgac caccatcata
    10201 gggtaaatca ggtcattgag ccaagtcaaa ctatccatga gcacagccat aagacaggca
    10261 atcaaaactc ccaaaatcag ccccagtaaa gccactctca aggtcgccca gctatggtgc
    10321 cagagaaatt ctctgtcacg aacaaagggc tggagaattt caagaggtgt cggcaggata
    10381 aacttgggga gaagtttaag aaaacctgct aactgccaga ttaacaagac tccgagaaag
    10441 cccaatagac taatgtgtcg tctcagtata cttctcaagt ttctcatcaa tacttaaaat
    10501 ctctcctaca tttattttga cattggcaaa gacattgtct gcctcctgcc ctgccacttc
    10561 cagcgcttct tttagaatgc gcataagctc atcaaactcc ccttccaaga ccgtttcaaa
    10621 tggtgtcact accatcgtca cttcttgagt ttgcagataa gcaatgacct gatcaataac
    10681 agctatccga tcaatcccct gtgctagggg taaaacttgc aaggcaatgc ttgctttcat
    10741 aagaacctcc tcttctcgtt ttccttttta aaaaaagaaa aacctttacc atacatggaa
    10801 aaggtgcaaa attagactaa gtatcgttcc ctccgctggc attacccaga tcaggtgcgg
    10861 tcgaagttta acacttcctc tcagactgta cacagactcc catatattat atgtatatat
    10921 gatagcgcaa aataagaaaa atgtcaagga aactgcttac agaaaagagc aggaaatttc
    10981 tcctactcca attttctata ctcgttctcc atcactgttt actctgtagc catccaccgt
    11041 cgtattaaca gctaaggcgc ctgaagagta agaataatac cacttaccag agacctggta
    11101 ccagcctgtt ttcattgccc ctgaactacc cagataatac cacgagccat tctcctttaa
    11161 ccatcctgtc tgcatttcac cagataattt caaataatac cagctagaac cgtctttcag
    11221 ccatcctgtt gatttagaac catttgattt gaaatgatac caactaccat ttattttctt
    11281 ccaaccgaca gttgaactat tattggatcc atagctagag atatttcctg attgattctg
    11341 ataattttgt gaagaagtca ctccctctag ctgtatatag cgacgacttc cattataggc
    11401 agtataactc aaccacttgt agccgtcttt ttcaagtatc tgatcataat gaaccttctc
    11461 tccaggataa tagtaatcaa tcacagttcc gctaactagg ggttcagttt tgatagcaga
    11521 cttggtctta aaataatgag ttccacctgt tgaagaaaga acagaattac ctagaggatt
    11581 tttattcaca gcctccaatt gaacataacg atagcttcca ttataggcag tataactcaa
    11641 ccacttatag ccgtcttttt caagtatctg atcataatga accttctccc caggataata
    11701 gtaatcaatc acagttccgc tagctagggg ttcagtttta atagcagact tggtcttaaa
    11761 ataatgagtt ccgcctgttg aagctgagga ttgactattc ccaacactgc cgccatccaa
    11821 atctttaaaa tgaataaatc ctgtcatcgt gtttgctttt ataactcgtt tattatagga
    11881 ttctgtataa ccatagttat attcctcaat ctcaatctga tctcccatta catttgacac
    11941 ccaggcaaca tgaccataag ttcctgcagt agaccaagta atggaaccaa tcgtcggtgt
    12001 attatctaca cgataacctt cccgacgagc acgatgtccc cattcattcg catttccata
    12061 agctgccgga atttcaaaac cattgacatt actcaaacga aaggctacaa aagaagtaca
    12121 ctgacgagaa tacatgcgcc actgatcaat ctcctggctc ccatttttat aataagcagg
    12181 ataatcatcc ccacgcgcaa tcgatccatt tcctccggaa taggcataga cactatcacc
    12241 agctgctagc atcaatccta ctactaaaaa aggaacaagc tttttaactg acatcttcaa
    12301 gtaataactt gtccctcttg ctataaacgg taaaattttc attcttcctc cttgaaaaat
    12361 aatataaagc gatgattgcc ttcacctaaa ttattcggag aaaaaagaaa aagtgagaaa
    12421 atttctcact ttagtcaaga taatgaatca aattcttttc tgtaagaata tctgagtaag
    12481 taaaggattc aacgtaaaca ttaacttgtt tatctccttc cacatcccca aactccacaa
    12541 taaatagaga tggataaact tcaattagct tacccaatct atttttttgg cgcttacgac
    12601 cattctccaa agtcatttct acgacttgtc cctcatgtgc cttgatttct tctttgattt
    12661 ttttcatctt ggctacatct gtaaatgcat ctgacatctt atgcctccct ctttgagata
    12721 cttgaaaatt tattgtattc tttttggaaa atcaattcca ctgttccacg agctccacta
    12781 cggtttttct cgataataac ttccacctta ttatttggga taccctcctc ttcttcacca
    12841 ccacgttcat agtagtcatc gcgatagaga aaagctacga tatcagcgtc ctgctcaata
    12901 gacccagatt cacgaatatc agacaagacc ggtctcttgt cctgacgttg ttctacacca
    12961 cgagaaagct gactcagagc gattactgga accttcaatt ccttggctag tattttcaac
    13021 tgacgagaaa tttcagaaac ttcttgttga cgattttctc gaccagttcc cgtgataagt
    13081 tgcaaatagt ctatcaaaat caaaccaaga tttccagttt cttgagccaa tttacgagaa
    13141 cgagaacgaa tctctgtaat ccgaatacct ggcgtatcat cgatatagat actggcgtta
    13201 gctagattac cctgagcaat agtatatttt tgccactcct catctgtcaa ttgccctgta
    13261 cggatagaat gtgactccac taagccttct gcagctaaca tacgatctac caagctttcc
    13321 gcacccattt cgagtgaaaa aatagcaacc gttttgtcca acttagtccc aatattctga
    13381 gcgatattca aggcaaatgc tgtcttacca actgctggac gagctgctaa gataatcaac
    13441 tcctcctcat gaagtcctgt tgtcatatga tccaaatcac gataacctgt cgcaatacct
    13501 gtaatatcgg tcgtttgttg cgagcgagct tccagatttc caaagttgag attcaacaca
    13561 tctcgaatgt tcttaaaccc gcttcgattt gcattttcac tgacatcaat caaccctttt
    13621 tctgcctgag caataatttc atcagctggt tgtgacgctt cgtaagcttg gttgacagac
    13681 tctgtcaact tggcaattaa acgacgtagc attgcttttt ctgcaacaat cttagcataa
    13741 tactccgcat tagcagaagt tggcacagaa ttaacaatct caaccaagta agacaagcca
    13801 ccaatattct gtaaatcacc ttgattatca aggatagtac gaaccgttgt tgcatctatg
    13861 gcatcaccac gatcggataa atcgaccatg gcttggaaaa tcaaacgatg ggcatactta
    13921 aaaaagtccc gagactcaat gtattctcgc acaaaaacaa gtttactctc atcaataaag
    13981 atagccccta aaacggattg ctcagctaag atatcttgag gttgtactcg taactcttct
    14041 acttctgcca tcagacttcc cttcttttac aatcttgtca agaaagtgta aacttatcct
    14101 tctttcacac gaagattgat tacacttgtg atatcttgat agattttcac tggcacatca
    14161 atcaaaccaa ccgctcgaat cggagcttgt acttgaatat gacgtttatc aatcttaatt
    14221 ccaaattgct tttgcaattc ttctgcaatc ttcttattgg taatagaacc aaaggtacga
    14281 ccatctggac caactttttc aacaaattct acaacagttt cttctgcttc aagttgtgct
    14341 ttaattgctt ttccttctgc aatcatctca gcgtgagctt tttcttccga tttttgttta
    14401 ccacgaagtt cacctacagc ttgagcagtc gcttctttgg ctagattctt tttgataaga
    14461 aagttttgcg cataccctgt tggtacttcc ttaatttcgc cttttttacc ttttccttta
    14521 acatctgcta aaaagattac tttcattctt ctttctcctt ttcctttatt tcatttaata
    14581 caatttctgt cagtttttca cctgcttctg acaaggttac atctttaatt tgagctgctg
    14641 ccaaattaaa gtggcctcca ccgcctaact cttccataat ccgttgtaca ttcagtttac
    14701 tacgacttcg agctgagata gagataaatc cttgtgtatt cttcgcaaga acaaaactcg
    14761 cttcaatacc tgacatggct aacatggcat ctgctgcctt actaataaca actgtatcat
    14821 agcatttcgt gtccttagcc tctgctatta gtacatctga acctaattta cacccctgta
    14881 aaataagttc attgacctca cgatattctt caaaatctgt cgcagcgatt tcctggatag
    14941 caatactatc acttccgcgc gttctgagat agctagcaac atcaaatgtc cgactagtta
    15001 ctcgcgaggt gaaattttta gtatccaaca tcataccagc catcaaaaca cttgcttgca
    15061 tacgactcaa acgatttttc ttagaattct ggaactgaat caattccgtt accaactcac
    15121 tggcactact tgcaccactt tcgatataag taataaccgc attatctgga aaatcctgat
    15181 cccttctatg gtggtcaata acaatgattt gggtaaataa atcataaaat tcttttgata
    15241 atgttaaggc tgtctttgaa tggtctacaa gaatcaacaa agaacgattg gtcaccatcc
    15301 ccattgcatc cttaacagac aacaacttcg taactccttc tttttctatg aatgaaacag
    15361 ctcgttcaat atctggagac atttgttctt catcataaag agcatagcta ttttcaatca
    15421 cattgctggc gaacaactgc atacctacag cagagcccaa agcatccatg tctaaatttt
    15481 tgtgaccgac tacaaaaacc tgatctacac tccgaatctt atctgaaata gctgtcatca
    15541 tagcgcgcgt acgagtccgt gtacgcttga ttgaagcagc agacccacca ccaaaataaa
    15601 ctggattttt cgtttcgtcg ttttccttaa caaccacctg gtcgccacca cgtacttcag
    15661 ccaagttcaa attgagcaaa gcaactttcc ctatctcatc atgatttcca tcgccataag
    15721 aaaatcccat acttaaggtc aagggcaact gtctctgttt cgactcttct ctgaaagcat
    15781 caataacaga aaatttatca ttcatcaagc cctcaagcac cgtgtagtca gtaaatagat
    15841 aaaatcgatc catacttacc cgacgagaaa acatcatgta tttttctgaa aactctgata
    15901 taaaattagc tacaaaacta ttgatttgac taatatctga ctcagaagtt gcatcctcca
    15961 aatcatcata attatccaca gagacaatcc caatcactgg tcgacttgtt accaattcat
    16021 ctgttatggc ttgttccctg gatacatcta caaaatacaa aacaccggaa gaagcatcca
    16081 tatgaacagc ataacgcttc tcaccaagct tggcataagt agacggattt cctactgaag
    16141 ccttgataat cgtttgaaca gcttctaaat caaaatcacc atcttccttg gtcaaaatca
    16201 attcagcata gggattaaac cactcaacct ctccagaaga taaattcaat ttcataacac
    16261 ctacaggcat ctgttccaat agagctgtca aactttcttc cgcttggtgg tttacatact
    16321 gtatctgttc tacatcactc cttgtataat gcactctcag tttcttaaat aaaaaaacat
    16381 agcctcctac aaaaagaaac aaaattaaaa ccgtcaacag attattatta acaaaaataa
    16441 tgaaagtgga taagactcca aacgcaatca atcctactag aataggaaaa attggactta
    16501 cataaaattt tttcattcaa aacctcttgg cacccattat accataatac ccctcaaaaa
    16561 gcgacttttt aaaagtgtaa tcagtaattc tatcaattat aagaaaaagg tagtttacaa
    16621 ttcagtaaac ctacctttac acatattgaa attaagattc tttaacctct aacaaaccaa
    16681 tttcgccatc ctcacgacga taaatcacat tggttgtctg atcttcaaca tccacataga
    16741 taaagaaatc atgccccaat aaatccattt gtagaattgc ttcttccaaa tccattggtt
    16801 ttaaatcaat ttgttttgaa cgaacaactt tagactggac aatatttgaa tcttccacca
    16861 aagcatctgt aaataattga ccagttgcta ccttattttt atttttacgc tcgatttttg
    16921 ttttattttt acgaatctga cgttcaattt tatcagttac aaggtcaatt gaaccataca
    16981 tatcttgaga tacatcttct gcgcggagag taatagatcc aagcggaatc gttacttcca
    17041 ctttagccgt tttttcacga taaactttta agttaattcg ggcatccaac tcttgttctg
    17101 gttggaagta cttttcgatc ttttcgagtt tagaaactac ataatcacga attgcttctg
    17161 ttacttctag gttttcacca cggatactat atttaatcat atgagtacct tctttctaaa
    17221 catttttgtt tttatgattt tattataacg ctttcattct atttttgcaa attttttcct
    17281 catcttacaa gggaaaatgt ttttacatcc ttagcaccag cttcttccaa cagtttctta
    17341 acacgattta tagttgctcc tgtagtatag atatcatcta taagtaggat ttttttagga
    17401 atagtgactc cacttttaat aaagaaagga agttctgtcc ccaagcgctc tgaacgattt
    17461 ttagaagaac tggctctctc ttctcttttc tctaataaat ccagatactc aaagcctgct
    17521 gcctctacca agccctcaac ctgattaaat cctctgttag catatctatc aggacttagg
    17581 ggaattacaa caaattgata ctctttgtac tttttcaact cctcacttaa aaatgaagcg
    17641 aaaacttttc ttaacaggaa gtctccatca aacttatacc gactgaaaaa atccttcata
    17701 gcttgattgt aagtaaaaat cgctctatga ctgacttcaa ctccttcttt acaccaaagt
    17761 tgacagtctt gacactttgt tgacaactct gttttcatac aatttggaca gttctcttcc
    17821 ccaattcttt caaaagtaga atcacagtct gaacaaagac aagagtcatc attcctcaga
    17881 agtaagagac tactaaaagt taaaacagtc ttcatagtct gcccacataa caagcacttc
    17941 atagaccagc ctccttattc atcatctgaa tttccttaat cgccttcttg attgaagcat
    18001 ttaacccatc atggaagaaa agcaaatctc ctgtcggtct atccatgctt cgtccaactc
    18061 gtccaccaat ctgaatcaaa ctagacttgg taaacaaacg atgattggcc tctactacga
    18121 aaacatccac acaagggaag gtaactccac gctccaagat tgtcgtactg ataagtattg
    18181 tcagttctcc atctcgaaaa gcttgtactt gctctaatcg atcctctgtt acagaagata
    18241 caaagccaat tttctcattt ggaaattgct cctgtaagat ttcttctaac tgctcccctt
    18301 tcttaatttc tgaagcaaaa atgagtaacg gataagctgt ctttctctgc ttctcaatat
    18361 aggactttaa ctttggtgac aaacgattct tgtctaagta gcgattaaaa tccgataacc
    18421 aaattggttt tggaataatc aacggatttc catgaaaccg tctcggtaaa ctcagtcttt
    18481 ttagttctcc taaacggacc tttttatcta actcattggt cgaagtcgct gttaaaaaga
    18541 ttctcaatcc attctccttt acactattct tgacagcgtg gtaaagcgtg ggattatcaa
    18601 cataaggaaa agcatctact tcatccacta tcagcaaatc aaaagcttga taaaacttca
    18661 ataactgatg ggttgttgca acaactagtg gtgttcgaaa ataaggttcc gattctccat
    18721 gtagcaaagc tatcccgcaa gaaaaatcct gttgcaggcg cttgtacagc tccaaacaaa
    18781 catctatgcg aggactagcc aaacacactg caccacccgc attgatcact ttagccacta
    18841 cttgataaat catttctgtc tttccagctc ctgttaccgc atgaactaag gttggctttt
    18901 gcttgtctac tgcttgaagc agtccctctg acaccttctc ttgaaaagga gttaattggc
    18961 cgcgccattt gagaacatct tgcttcggaa aatcctcctg cggaaaatag tataaagttt
    19021 gatcacttct gactcgcttc atcagcaagc actctcgaca atagtaagca ccgatgggca
    19081 aataccattc ttctagaata gtactattac aacgttgaca gaaaagtttc cccttctcct
    19141 ttctcattgc tggaagtttc tccgccaact gacgttcttc ttctgttaat tcattctcag
    19201 taaataaacg accgagataa tctaaattta ctttcatact tctttattcg taaaaactag
    19261 cactttagat tattttttag tacaattaaa tcatggaatt taggacaatt aaagaggacg
    19321 gccaagtcca agaagaaatc aaaaaatctc gctttatctg ccatgccaag cgtgtttata
    19381 gcgaagaaga ggctcgtgac ttcattactg ccatcaaaaa agaacactac aaagcgacac
    19441 ataactgctc tgcctttatt attggagaac gtagtgaaat taaacgtaca agtgatgatg
    19501 gtgagcctag tggtactgct ggtgttccca tgcttggggt actagaaaat cacaatctca
    19561 ccaatgtctg tgtggtcgtg acacgctact ttggtggtat taaactaggc gctggaggac
    19621 taattcgtgc ttacgccggc agtgtcgcct tagctgtcaa agaaattggt attattgaaa
    19681 taaaagaaca ggctggcatt gctattcaaa tgtcttatgc tcagtaccaa gagtacagta
    19741 acttccttaa agaacatgat ctcatggagc tggatacaaa ctttacagat caagtcgata
    19801 cgatgattta tgttgataaa gaagaaaaag aaactattaa agctgcactt gtggagtttt
    19861 ttaatggaaa agtcacttta actgaccaag gtttacgaga ggttgaagtt cctgtaaact
    19921 tagtgtaaac aatgaataat acagcgtttc gttgacattc tcacaactac tttagcgagc
    19981 aaaataaaaa gatgcgtacc aaaatatact agaaaatgaa gcaattcaaa cgaaacctga
    20041 tatcgttttc cttcacacct atttactaga attaactgaa cgcaatcact tgaaaattaa
    20101 tgactttgat ctatgatata tagaaatcct atcgcttcga taggatttct atattttaca
    20161 aatggtatgg atagcgttat actaaagata tcttatacaa agaggtattc atatgtctat
    20221 ttataacaac attactgaat taatcggtca aacaccgatt gttaaactta acaacatcgt
    20281 gccagaaggt gctgcagacg tctatataaa gcttgaagca tttaatcctg gttcatctgt
    20341 aaaagaccgt attgccctta gcatgattga aaaagctgaa caagatggta ttctgaaacc
    20401 tggttctact attgttgaag caacaagtgg aaacactggt attggacttt catgggtagg
    20461 tgctgctaaa gggtataaag tcgtcatcgt tatgcctgaa actatgagtg tagaacgacg
    20521 taaaattatc caagcttatg gtgctgaact cgtcctaact cctggtagcg agggaatgaa
    20581 aggtgctatt gctaaggctc aagaaatcgc tgctgaacgt gatggtttcc ttcctcttca
    20641 atttgacaat ccagctaatc cagaagtaca cgaaagaaca acaggagctg agatactagc
    20701 tgctttcggt aaagatggat tagatgcctt tgttgctgga gtaggtaccg gtggaacgat
    20761 ttctggtgtt tctcatgcac tcaaatcaga aaattctaac attcaagttt ttgcagtaga
    20821 agcagatgaa tctgctattc tatctggtga aaaacctggt cctcacaaaa ttcaaggtat
    20881 ctcagctgga tttattcctg atacacttga tactaaagcc tatgatggta tcgttcgtgt
    20941 aacatcagat gacgctcttg cactcggacg tgaaattggt ggaaaagaag gcttccttgt
    21001 agggatttcc tcagctgcag ctatctacgg agccatcgag gttgccaaaa aattaggtac
    21061 aggtaaaaaa gtccttgtcc tagcaccaga taacggtgaa cgttatctct ctacagcact
    21121 ttatgaattg taaccgtcca ataacgaagt atattgaaaa atctccagac tagagaactc
    21181 acggatagtt cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca
    21241 tggtaaataa gcctctaaaa cctctttgtt tacgagagtt tccacgtttg gaagacattc
    21301 tagaagatag gatagatatt tctcactatt tataatggat tgaaataaga tatgaacaaa
    21361 tcgattagga catgatggta aagcgtaatc ccttgtttct cagctttccc agacaaaaaa
    21421 gtccaatagt aagtcagctg actatcactc tctagcaccc tataagaagt ttcatccgca
    21481 tgaagtaagg gctgagtcaa tagtctctct cgcaagaggt tatagagggg ctccaaatag
    21541 tattgactcg tcttgatatg ccaattagag atttccttgc gtgtgattgg taaacccatc
    21601 ttagcccaat cttcttcttg gcgataattg ggtaccttca gattaaactt ctgatggatg
    21661 gtgtgagcga taatagaagc tgagccaaag ctatgcgc
//
LOCUS       DBERAE010000036        21431 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.36, whole genome shotgun sequence.
ACCESSION   DBERAE010000036 DBERAE010000000
VERSION     DBERAE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.36"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..464
                     /locus_tag="ACL70N_001587"
     CDS             <1..464
                     /locus_tag="ACL70N_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HGS0590357.1"
                     /translation="RLPTFAFIFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDNLFE
                     KGKNEIKDPIGTNSVLNKKIILQKIRKLSNQPSGYWIGSLDERFLDHAIINQIDVTSE
                     QIVLMSDGFYEFYQNNQNKTFEELIKMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            522..1061
                     /locus_tag="ACL70N_001588"
                     /pseudo
     CDS             522..1061
                     /locus_tag="ACL70N_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
     gene            1076..2551
                     /gene="galT"
                     /locus_tag="ACL70N_001589"
     CDS             1076..2551
                     /gene="galT"
                     /locus_tag="ACL70N_001589"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS0590358.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2564..3574
                     /gene="galE"
                     /locus_tag="ACL70N_001590"
     CDS             2564..3574
                     /gene="galE"
                     /locus_tag="ACL70N_001590"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0590359.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3754..4413
                     /locus_tag="ACL70N_001591"
     CDS             3754..4413
                     /locus_tag="ACL70N_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGS0590360.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            4438..5505
                     /locus_tag="ACL70N_001592"
     CDS             4438..5505
                     /locus_tag="ACL70N_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0590361.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            5609..6619
                     /locus_tag="ACL70N_001593"
     CDS             5609..6619
                     /locus_tag="ACL70N_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590362.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6631..8322
                     /locus_tag="ACL70N_001594"
     CDS             6631..8322
                     /locus_tag="ACL70N_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590363.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            8325..9035
                     /locus_tag="ACL70N_001595"
     CDS             8325..9035
                     /locus_tag="ACL70N_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS0590364.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            9131..9499
                     /locus_tag="ACL70N_001596"
     CDS             9131..9499
                     /locus_tag="ACL70N_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590365.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            9607..10608
                     /locus_tag="ACL70N_001597"
     CDS             9607..10608
                     /locus_tag="ACL70N_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0590366.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            11213..11419
                     /locus_tag="ACL70N_001598"
     CDS             11213..11419
                     /locus_tag="ACL70N_001598"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590367.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NHTYGKATLTRFEEIFEEYKGVPR"
     gene            11791..13152
                     /gene="trpE"
                     /locus_tag="ACL70N_001599"
     CDS             11791..13152
                     /gene="trpE"
                     /locus_tag="ACL70N_001599"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGS0590368.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            13149..13715
                     /locus_tag="ACL70N_001600"
     CDS             13149..13715
                     /locus_tag="ACL70N_001600"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGS0590369.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            13726..14730
                     /gene="trpD"
                     /locus_tag="ACL70N_001601"
     CDS             13726..14730
                     /gene="trpD"
                     /locus_tag="ACL70N_001601"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGS0590370.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            14727..15494
                     /gene="trpC"
                     /locus_tag="ACL70N_001602"
     CDS             14727..15494
                     /gene="trpC"
                     /locus_tag="ACL70N_001602"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGS0590371.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            15481..16080
                     /locus_tag="ACL70N_001603"
     CDS             15481..16080
                     /locus_tag="ACL70N_001603"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGS0590372.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            16058..17281
                     /gene="trpB"
                     /locus_tag="ACL70N_001604"
     CDS             16058..17281
                     /gene="trpB"
                     /locus_tag="ACL70N_001604"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGS0590373.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            17274..18050
                     /gene="trpA"
                     /locus_tag="ACL70N_001605"
     CDS             17274..18050
                     /gene="trpA"
                     /locus_tag="ACL70N_001605"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGS0590374.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(18022..18123)
                     /locus_tag="ACL70N_001606"
                     /pseudo
     CDS             complement(18022..18123)
                     /locus_tag="ACL70N_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            18352..19083
                     /locus_tag="ACL70N_001607"
                     /pseudo
     CDS             18352..19083
                     /locus_tag="ACL70N_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19098..20249
                     /locus_tag="ACL70N_001608"
     CDS             19098..20249
                     /locus_tag="ACL70N_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0590375.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(20301..20960)
                     /locus_tag="ACL70N_001609"
     CDS             complement(20301..20960)
                     /locus_tag="ACL70N_001609"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGS0590376.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            21030..>21431
                     /locus_tag="ACL70N_001610"
     CDS             21030..>21431
                     /locus_tag="ACL70N_001610"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0590377.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQM"
BASE COUNT         7056 a         3340 c         4562 g         6473 t
ORIGIN      
        1 atcgcttacc aacatttgct tttatatttg ctaaactttc agaaaaaaag ttggagtata
       61 tgatgctagg tgactgcgtc atgttagtaa acgaaatgga aataacggat catagagtag
      121 ataacttatt tgaaaaaggg aaaaatgaga taaaagatcc aattggtaca aatagtgttt
      181 taaataaaaa aattatttta caaaaaatca gaaaattatc taatcaaccg agtgggtact
      241 ggataggttc gttggatgag agatttttag accatgctat tattaatcaa atagatgtta
      301 ctagtgaaca aattgtttta atgagcgatg gcttttatga attctatcaa aataatcaaa
      361 ataaaacttt tgaagagtta attaagatga gatttaattc ttctgctatt gatccaatct
      421 atggaaagaa agatgatgca agtattgtag ttattgatgt ttgatatatt gtttaaaata
      481 ttaattgtta ctattgaact ttgttaagaa gaggtaccta aatgttaagg ttatatttag
      541 aaaatgaaat tatagaatta tcaaataatt tagagaccat ttgggtatct gtgcttgata
      601 aatatgagaa gttatttgaa tatttatcaa atgaagaacg aatagaattg attaaagaag
      661 atttaatcat aaatgagtca gttctaaatg ttgataaaaa aggatatgag ttaatttgtt
      721 tacaacatcc cgtttcatat gacttaagaa gaattattag tgtaataaaa atatcaactg
      781 acattgaacg tattggggat agaattgttg aaattttaaa aaatctacag attattcaaa
      841 ataatgaaat tttgaagaaa attatttcag aaataaaaat acttcatgaa gttatcggac
      901 tgcatatgaa tagggctata tcttgttata gagaggaaca atctggatgt ttagatatgg
      961 ttgttataca aaaacagaat gagatagaag agcttagtac aaatattgaa aagaaaataa
     1021 tgaattacat atttgaagat gatgggaatg tttctgaaat tagaaagaaa aatatatgaa
     1081 aacaattatt gataattttg ttgatagagt aattgaatac ggaatgtata atgaaattga
     1141 caaaatatat gtgaaaaata gagtactagc gttaataggt gaggagggaa ctgatcgcat
     1201 ttccgatgaa aatgacctga aacaaataaa agattactta gtggaaatcg ccttaaaaaa
     1261 cggtaaaatt aaagatttaa tcgaggaaaa ggaatgttta ggagcagagt taatgaattt
     1321 catagttcct ttacctagtc gattaaatga tattttttgg agttcatatg atatatcacc
     1381 tcaagaagca gttgaagagt tttataagtt aagtaaagat agtgattata ttaaaacttc
     1441 tgctattgct aagaatattg agtttcgagc atcaactaaa tacggagagc tagagattac
     1501 gataaatttg tcaaaacccg aaaaagatcc aaaaacaatt gctgctgaaa aattagtaaa
     1561 agccactaat tatcccaaat gtttactatg tatggaaaat gaaggatatc aggggcgaat
     1621 aaattatcca gcacgttcga atcatagaat tattcgattg aaacttggtg acgaagtatg
     1681 gggattccaa tattctccct acttatactt taatgagcat gcgatatttt taaatagtca
     1741 acatgtacca atggctatta cctctaaaac atttgaacaa ttattggaga ttgttgatat
     1801 tttgccagga tattttgctg gttcaaattc tgatcttcct atctcaggag gctccattct
     1861 tagtcataac cactaccagg gagggaaaca tattttccca atggaaaaag caaaatttga
     1921 gagtgaattt cgttttaaag actttgagga tgttaatgct ggtattgtaa aatggccaat
     1981 gtcagtaatt aggttacaaa gtgaaaataa aaatcgcttg ttagatttag ctactaaaat
     2041 tctaaataag tggagagaat attcagattt agaagtagac atcattgcta tgactgaaga
     2101 tgtcccacac catacggtga ctcctattgc tcgtaaagtg gacgggagat atgaattaga
     2161 tattgttcta agagataatc atactactga acagtaccca gatggtgttt tccatcctca
     2221 tcaagatgta caacatatta aaaaggaaaa tatcgggtta atcgaagtga tgggacttgc
     2281 gatattacca cctcgtttga aaccagagtt agaagaagtt ggaaaatatc ttttaggaga
     2341 ggataacgca attgcggatt atcatttaga atgggccgac caattgaaag aaaaatatcc
     2401 tcgcattaat aaagaagagg ttaatagcgt agttcaacac gaagcaggac aagtgtttgc
     2461 gagagttctg gaagatgcag gagtttataa gaatacaccg tctgggcatg aagcgtttat
     2521 gagatttgtt aagtcggttg gaattaatta ggaggaaaca aaaatggcaa tattggtaac
     2581 aggcggagct ggttatattg gtagccatac cgtagtagaa ttactaaatt taggaaagga
     2641 agtcatcatt gtcgacaacc tttcgaactc tagcatcttg gtgctagacc gtattgaagc
     2701 aattacagga atacgtcccg tgttttacga attagatgtt tgtgataaac cagcattgag
     2761 aaaggtattt gaacaagaat cgattgatgc tgcaattcat tttgcaggtt ataaagctgt
     2821 cggagaatcc gtgcaaaagc ctgtgatgta ctacaaaaat aatattatga gtacattggc
     2881 acttgttgaa gtgatgtcag aatttaatgt taaaaagatt gtcttttctt caagtgcgac
     2941 tgtatatgga attaacaatc agtcacctct aattgagact atgcaaacaa gtgcgacaaa
     3001 tccttatggg tatacgaaag tgatgcttga gcaaatttta aaagatgttc atgtggcaga
     3061 ttcagaatgg agtattgcgt tgcttcgtta tttcaatcca attggtgctc atgagtctgg
     3121 tttgattggg gaagatccct caggaattcc taacaacttg atgccctata ttgcacaagt
     3181 agcggtaggt aagctgtcag aactaagtgt gttcggaaat gattatgata cgcttgacgg
     3241 tactggtgtg cgcgattata tccatgtagt agatttagca ataggacata taaaagcttt
     3301 agaaaaagta tctgaaaaaa cagatgttta tatctataac ctaggctcgg gagaaggcac
     3361 tagtgtatta caacttgtaa atacatttga aagtgttaat aagatcccta ttccttataa
     3421 aatagttcca agacgttcag gagacgttgc aacttgttat gcaaatgcag acaaagcata
     3481 taaggaatta aattggagga caacaaaatc gattgaagac atgtgtagag atacatggaa
     3541 ttggcaatca aaaaatccca atggctataa ttgatgatac tgtctatatg agtgctgtat
     3601 tttggaaaaa ttacttaacc ttttaatgaa atgcatattt aatgaaagat aaattaaaaa
     3661 aaatgtttga cagcgcttga caaaggaaac ggtttcattg tataatgtaa acacaatgac
     3721 accgatgtca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa aattaagttc
     3781 aaagaaaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa tctttatact
     3841 aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga attaccattt
     3901 atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat tgaattgttg
     3961 tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga tacaccttta
     4021 caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt ggatgaagaa
     4081 attcatatgc gtataactga aatgggaaaa caaaacatac tagttgaacc tgcagatgaa
     4141 gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc aggtgtttgt
     4201 ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg gattcctcta
     4261 accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga aattttatta
     4321 gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga agatatgagg
     4381 caatttgttc catatcacga aaaatttaaa taaaataata aaaaaggaga acttatcatg
     4441 aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac tacacttgct
     4501 gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa agctgataaa
     4561 agtcaagaat tagttatcta ttcgaactca gtctcaaatg gtcgtggtga ttggttaact
     4621 gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatcgctgg cgctcaatta
     4681 gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt tggaattggt
     4741 gctgttgact caaataaaat tagagatcaa aaattactag tacagtacaa gcctaaatgg
     4801 ttagataaaa ttgatcaatc tttatcagat aaagataatt attataatcc tgtgattgtt
     4861 caaccattag ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga ttggactgaa
     4921 ttaggtagta agtataaagg taaatattca atttatggtc ttcaaggtgg tacaggacgg
     4981 gcaattctag caagtatctt agttcgttac cttgatgaaa aaggagattt aggcgtatca
     5041 gaaaaaggat gggaagttgc aaaagaatac tttgcaaatg cctatactct tcaaaaaggt
     5101 gaaagctcag ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg tatgatctgg
     5161 ggttctggag cgttaattgg acaaaaagaa caaaatgttg aattcaaagt tatgactcct
     5221 gagattggtg taccatttgt aactgaacaa actatggttt taagcactag taaaaaacaa
     5281 gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt agaatatagt
     5341 aaaaaatttg gatctattcc tgccaataaa gatgccctaa aagagttacc tgaagatacg
     5401 aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt tggaaagcat
     5461 ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat aagagttatt
     5521 ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag agaggctttt
     5581 ggttttagta atagagggag ttagtgagat gattaaattt gataatattc aaattaaata
     5641 tggtgatttt gttgcaattg ataatctgaa tttagatata catgaagggg aattctttac
     5701 atttcttggg ccttcaggat gtggtaaatc aactactttg agagcattgg taggtttttt
     5761 agatccatca tcaggaagta ttgaagttaa tggaacagat gtcactcatt tggaacctga
     5821 aaagcgtgga attggtattg tatttcaatc ttatgcgcta tttccaacta tgactgtttt
     5881 tgataatatt gcatttggtt taaaagttaa gaaggtagct ccagatgtta ttaaagctaa
     5941 agtatcagca gtggcagcaa aaattaagat ctctgatcaa cagttacagc gtaatgtatc
     6001 agaattatct gggggtcaac aacaaagggt agcattggct cgtgctctgg ttcttgaacc
     6061 taaaattctt tgtctagatg aaccattgtc aaaccttgac gcaaaattac gtgtagattt
     6121 gagaaaagag ttgaaaagac ttcaaaaaga gttaggtatt actactttat atgttactca
     6181 tgatcaagag gaagccttga ctttatctga tagaattgca gtctttaaca atggatacat
     6241 cgaacaggtc ggtacaccag tagagattta tcataattct caaactgaat ttgtatgtga
     6301 ttttattgga gatattaatg ttttgaccga tgaaacagtc cacgaagtat tactgaaaaa
     6361 tacaagcgtt ttcttagagg ataaaaaagg ttacattcga ttagagaaag ttcgattcaa
     6421 tcgtgaaact gaacaagatt ttattctaaa agggacaatt attgatgttg agttttctgg
     6481 agttacaatt cactatacaa taaaagtttc tgaaagtcag attcttaatg taacaagtat
     6541 tgatagtcag gctgctatta gatctgtcgg agaaagtgtg gaattattta tcacaccatc
     6601 agacgttctg caattttaag gaggtgcagt atgcgtcata aattaaattt aaaagattgg
     6661 cttattcgtt tagggttaat ctggttctta gtaacattta ttatttatcc aaactttgat
     6721 ctagtagtga atgtatttgt aaaaggagga gaattttccc ttgatgctgt acatcgtgtt
     6781 ctaaaatctc agagggcact tcagagtatt atgaacagtt ttaagttagc attttcactc
     6841 attattacag ttaatgtcgt aggtattctt tgtgttctat ttacagagta ctttgatatt
     6901 aaaggtgcta aaattttaaa attaggttat atgacctctt taatttatgg aggagtggtt
     6961 ttagcgactg gatataaatt tgtctatggt ccttatggat tgattacaaa atttttacaa
     7021 aatgttatcc cttctttaga ctctaactgg tttattgggt atggtgcagt cttattcatt
     7081 atgacatttt caggaactgc taatcataca ttgtttttaa caaatacaat tcgaagcgtt
     7141 gactatcaca ctattgaggc tgctcgaaat atgggagcaa aaccatttac tgttttccga
     7201 aaagtagtgt taccaacctt aattccaact ctatttgcac ttactattat ggtttttctt
     7261 agtggtttat ctgcagtagc agcacccatg attgttggtg gtaaagaatt tcaaactata
     7321 aatccaatga ttattacatt tgcagggatg gggaattctc gtgatttagc tgccttactt
     7381 gcaattattt taggtattgc aactacaatt ttgcttacta tcatgaataa gatagaaaaa
     7441 ggtggaaatt atatttctat ctctaagact aaagcgcctc ttaaaaaaca aaaaattgcg
     7501 tctaagcctt ggaatatcat tgctcacatt gtagcatatg gattgttcac agttttcatg
     7561 cttccactaa tttttatagt attatactca tttacagatc cagttgcaat tcaaacaggt
     7621 aacttaacat tatcaaactt tactttagaa aattatcgct tattctttag taatagtgcg
     7681 gcattctctc cattcttggt cagctttatt tattctatta ttgctgcgac aacagcaaca
     7741 attctcgcag ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt tgatttctta
     7801 tttgaatatg gtgctctact tccttggtta ctaccaagta cacttttagc agtaagttta
     7861 ttatttactt ttaatcagcc acaatttctt gtcttgaatc agattttggt aggtagtttg
     7921 gtaattctac ttattgcata tatagttgta aaaatcccat tttcttatag aatggtacgt
     7981 gctattttat ttagtgttga tgatgagatg gaagatgcag caagaagtat gggtgcttca
     8041 cctttttata ctatgatgaa ggttatcatt ccatttattt taccggttgt tctctctgtt
     8101 attgctttaa actttaactc tttattaact gacttcgact tatctgtatt cctttaccac
     8161 cccctagctc aaccattagg tattacgatt cgatctgcag gtgatgaaac agcaacatct
     8221 aatgcacaag ctctggtatt tgtttataca attgttctga tgattatttc tggaacggta
     8281 ttatacttca cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca gccactagtc
     8341 ttgggttatc aaatattgaa atagttgtca ggattgtttt atcagtagtc attggtagta
     8401 taattggttt agagagaggg agcaaatccc agcctgcagg catccgaact tatagtattg
     8461 tttgtctagc tgcatgtttg attatgatga cgaatgaata cgtatcttat aaatttggga
     8521 caggagatcc tacacgatta ggagctcaag ttatatcagg tgtgggtttt ctaggcgctg
     8581 gaacgattct tattacagat aaaaagaaaa ttacaggtct gacaactgca gcaggcattt
     8641 gggcttcggc aggaattgga ttagctattg gagtaggttt ttatgaggga gctcttttag
     8701 tagccatttc tgtttggggt gtgatatcca tgttccaacc actaaaaaaa tatctacaaa
     8761 atcgttctaa aatgattgaa ttgtatatag tagttaaatc tacagaagcc tataatcgtg
     8821 tattggttta ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca gcgtttggag
     8881 atgttaattc tgacagaatt gaatactttg atgttccaga taaaaaaata gcgtcattta
     8941 ttactctgga attatcaggt agatttgaac atcttcgact gatggaagaa attgctaata
     9001 ttgtaggtgt tatttatgtc gaagaaatta gctgaaattt agtaaacaaa gggacagatg
     9061 tttttgtcct tttgtttttt agatatttta atcatctaat ttttgagtag atttttgctc
     9121 agaggttttt atgaaagatt ataaaatcaa ttttgattta ggtaaaatag aatattttga
     9181 taataattgt ttgatacaag tatacaaatt tatttctttt tatgatattt gtgaaatggt
     9241 gtttgccttt catttacctc ctgatgagtt gataacaaat gttatcttta aagaaaaaat
     9301 taactctatg ttaaaatgtt acattgacag gctattatat gtttttataa atcctacaca
     9361 ttttactgaa aaagttaatc tacaatttta tggtagtttt ttctcatatg aatttatttg
     9421 tcgtgaagtt ggaaacattc ttaaaaataa aggtgtgaaa tgcaatttaa acttttttga
     9481 aggggaagaa tatttgtaaa attaattttg tgaatttgtg gatcttaaat aatttactaa
     9541 attctcttgt taaaaaaaat taaatattgt atagtaatat tagaatgttt gtaatagagg
     9601 actgaaatga aaaatataaa tgggaaaaag gtaactattt atgatattgc acgtttatca
     9661 ggtttttctc caaaaacagt ttcacgagtt attaatggtg gagtaaatgt taaagaagaa
     9721 acttatcaag cgattcaaaa agttatagag gaattgtcgt atattccaaa tgcgtatgca
     9781 aaaaatttaa ctaaaaaaga agctataaat atattgattt ctgtaaaaaa aatcgactct
     9841 tttcctttaa tttggtttca tacgctgtta gataaagtgt tacggacgtg taaagaattt
     9901 ggtgttaatg ctatagttga gtactttgga gaggaggata caattagtaa ttcaattata
     9961 tcaagcacag gtagcctagt agatggtgtt attgtttttt atgaaagtgt agatgatatc
    10021 agaattcagt atttaaagaa gaaccatatg ccttttcttg ttttcggtga atctcaaacg
    10081 tctggagtag tctatgtatc taataataat tttcaagcta cttatgatat gatgaaagct
    10141 gtaactgaag aaaaatttaa aaatatgtgg ttgcttatgg gaggagaatc ccatgttaat
    10201 aaggatcgtg aaagaggtgt gcgttctttt ctgaatgata aaaattactt tatggattta
    10261 aaagtcattt atggcttatc tacaattgat tcagtttatt cttatgcaat gcagcacttg
    10321 actacccaaa attatccgga cattattttt gtttcaggag atgaaaaggt tcagggcttg
    10381 attcgtgcgt gctatgagaa aggaattctt attccagatg atatttctat cattggattt
    10441 gataatattc ctatttctca gtattatact ccagctttgt ctacaattgc tcccaattat
    10501 gttaaattgg ctaaagaaat gatagaaggt gttttagcaa ttattaaagg ggaaagtgtc
    10561 acatctgttg aagtttctcc taaatttgtt aggagacaga gtttctagta ttgtttaatt
    10621 cttgaaaatc ctagtggaaa agatggagtg ttctaaaata agttctgttt agcctccatt
    10681 cagtttctat tgagttggat ccaatttcta acaagtggga catgttcatg ttcgatctaa
    10741 ggaagatatg gtcacattcg aatgatatca aaaaaatcgt aaaaaagtct tgacaaagaa
    10801 aaaacaaagt attaaaataa gttcaacaaa tcagaaaagt aactattttt gatcttcagg
    10861 gagcctgtgg tgattgtgaa taggtggttg gaagtagtga aagtgggctg attttgaaaa
    10921 tgaatttgaa acaatgaaaa ttcggtgcgc acaccttaca gtgcagcttg ttgttaaaca
    10981 aggcagagat gtaaagggat agtcccttta taattgaggt ggcaccgcgt taccaacgcc
    11041 ctcacacgga agtatattct gtgtgtgggc ttttttctat ccgtcgtttg gtttatcttt
    11101 tattagggcc ttaagtcgct ttgatgaact tgagttctat ctacagctcc ttgcctccta
    11161 ctaaaagtaa acaaaaaggc tggactaata cgaaaaaagc tagtaatact caatgaaaat
    11221 caaagagcaa actaggaaac tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
    11281 tagaactgac gaagtcagct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt
    11341 cagtaaccat acctacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta
    11401 taaaggtgta ccgagatgaa catctcttca tcaatgtctc tggtcgtgga ggcaaggacc
    11461 tagctgcgat tgcagattac tagaagctaa aaaataatag atggaaaaat tacagtcttt
    11521 tctctcacag agagcttgtg gttgctgaaa acaagcagag aaagctgtaa agttgggttc
    11581 atctgaaacg agagaagaaa acatcattct caagggagtg ccctttatcg cacagcctgt
    11641 tacaggagat atctgagaca ggaatgagag ataggagaaa tcctataatt gaggtggcac
    11701 cgcgaatttc gtcctcacgc aagttatttt gcgtggggat ttttcataca gtcgccacga
    11761 actagaatta gaactgaaag ggaaatgaca atggaacgaa tcattcatgg agatgtctta
    11821 tcaccaatct tggcttatat gcgcttaaag gggcaacata aggttatttt agagagtatt
    11881 ccgagagaca aggaaacagc tcgtttttct atcctagcct ataatccagt ttttgagatt
    11941 aagtttgaaa atggagttct ctatcaaaat ggtcaagcga ttgatcggga tcccttggat
    12001 ttcctttatg aagtgactca taagagccag caccattcag acctcccttt tggtggggga
    12061 gccattggtt ttgttggtta cgatatgatt tcgctttatg aagaaattgg tcaaatccct
    12121 gaggatacaa ttgggacgcc agacatgcat ttctttgtct atgagagcta tatggtcttt
    12181 gaccacaaga aggagaagat acatgtcata gaggatgcac tttatagtga gcgcagtcaa
    12241 gaggccttgg aaaaatcctt gaaccaagtg cttgaggaat tacgcattcc tgctccaaat
    12301 gaatttgaag acttggattt atcaccactt gacttcaaac cgcatatcgc tccacataag
    12361 tttgagggaa tggtagaaac agctcgtgac ttgattcgta acggagatat gttccaatgt
    12421 gtactcagcc agcgtttctc agcagaagtt actggaaatc catttgactt ctacagaaat
    12481 ctccgcgtga ctaatccatc taattacctt tatttctatg attttgggga ttatcaaatc
    12541 atcggagcta gtccagaaag tttggtttct gtcaaaaatg gcatcgtgac aactaatccg
    12601 attgcaggga cgcgaccaag aggggctacg gatgaagaag acaaggcctt ggcgactgac
    12661 ctcctctctg atgagaagga aacagcagaa catcgaatgt tggtagactt ggggcgtaac
    12721 gatattggcc gcatctctga aacggccagt gtccaagtta ctaagtatat ggaggtggag
    12781 ctcttccgct acgtcatgca tttgaccagt gtggtcaagg gacgtttgct tgcagaactc
    12841 actgccatgg atgccttgaa agcaacgctt cctgctggaa ccgtttctgg agcaccaaaa
    12901 attcgagcta tgagacgcat ctatgaactg gaaacggaaa aacggagcgt atatgcagga
    12961 gcaatcggct acttgtctgc gacgggtgat atggatttgg ccattgccat ccgaaccatg
    13021 attctcaaaa atcaaagagc ctatgtgcag gctggggcag ggattgtcta cgactctatc
    13081 gcccaaaacg aataccaaga aaccattaac aaagcaaaat ctatgactag aattggagaa
    13141 ctaagaccat gattttattg attgacaact atgattcttt tacctataac ttggcccaat
    13201 acattgggaa ttttgcagaa gttcaggttt tgagaaatga tgattccaag ctgtatgaag
    13261 aagctgaaaa agcagatggt ctggtctttt ctcctggtcc tggttggcca gttgatgctg
    13321 gaaagatgga agacatgatt tgtgattttg caggcaagaa gccgattcta gggatttgtt
    13381 tgggtcacca agccattgca gaagtctttg gtggtaagct aggtttggct ccaaaagtca
    13441 tgcatgggaa acagagcaat atcaactttg aagcgccatc tgttttgtat caaggtattg
    13501 aggatggacg tgcggtcatg cgttatcaca gtattttgat tgaggaaatg ccagaagact
    13561 ttgaagtgac agctcgttcg actgatgacc aagccatcat ggggattcaa cataaaaacc
    13621 taccgattta tggcttccag taccatccag agagcattgg aacgccagac ggcttgtctt
    13681 ctattcggaa ttttatcgag aaggttgtaa agtgaggaaa ctaggatgaa agagattatt
    13741 gaaaaactag caaaatttga aaatttatca ggtgtggaaa tgacggatgt cattgagcgt
    13801 atcgtaactg ggcgtgtaac tgaagcgcag attgcttctc tcctcttagc tcttaagatg
    13861 aagggggaaa cacctgaaga acgtacagcc attgcccaag tcatgagagg acatgcccag
    13921 catattccaa ctgagattca tgatgctatg gacaactgtg gtacaggtgg ggacaagtct
    13981 ttcagtttta atatttccac aactgcagcc tttgtcttgg ctggtggcgg tattcacatg
    14041 gccaagcatg gtaaccgctc gatttcttct aaatctggtt ccgcagatgt cctcgaagcc
    14101 ttgggaatca atcttgacct caaaccagct gaactaggta aggtctttga taaaactgga
    14161 atcgtctttc tcttcgctaa aaatatgcac ccagctatga aatacatcat gccagctcgt
    14221 ttggaattgg gaattccaac gattatgaac ttgactggtc cactgattca tccaatggct
    14281 ttagaaacac agcttcttgg aattagtcgt ccagaactcc tagaaagtac agctcaggtt
    14341 ttgaaaaata tgggtcgcaa acgtgccatc gtggttgctg gaccagaagg gttggatgaa
    14401 gctggcttga acggaacaac caagattgca cttcttgaaa atggcgaaat cagcttgtca
    14461 agctttactc cagaggattt gggaatggaa gactatgcta tggaagatat tcgtggtggg
    14521 aatgctcagg aaaatgcaga aattttgctt agcgttctga aaaacgaagc aagtccattc
    14581 ttggaaacga cagtcttgaa tgctggtctt ggtttctatg ctaatggtaa gattgatagc
    14641 atcaaggaag gagttgcctt ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa
    14701 ctcagactgt tacaggagta ccaaaaatga gtcaggaatt tttagcacga atcttagagc
    14761 agaaggcgcg tgaggtggag cagatgaagc tggagcaaat ccagcctctg cgccagacct
    14821 atcgcttggc agaatttttg aagaatcatc aggactgctt gcaggtaatc gctgaggtca
    14881 agaaagctag ccctagtttg ggagatatca atctcgatgt ggatattgtg caacaggccc
    14941 agacttatga agaaaacgga gcagtgatga tttcggtgtt gacagatgag gttttcttta
    15001 aagggcattt ggattatcta cgggaaattt ccagtcaggt agagattccg acgctcaaca
    15061 aagactttat catagatgaa aagcaaatca tccgcgctcg caatacaggt gcgacagtta
    15121 tcttgcttat tgtggcagcc ttgtccgaag aacgcctcaa ggaactgtat gactacgcga
    15181 cagagcttgg tctggaagtc ttagtggaga ctcacaatct agctgaacta gaggtagccc
    15241 acagacttgg tgctgagatt atcggggtca acaaccgcaa cttgactacc tttgaggtcg
    15301 acttgcagac cagtgtagat ttagcccctt actttgagga aggtcgctat tacatttctg
    15361 aatctgccat tttcacaggg caggatgcgg aacgactagc cccatacttt aacggaattt
    15421 tggtagggac agctcttatg caggcagaaa atgtggccca gagaatcaag gagttgcaga
    15481 ttgacaaagg ttaaaatttg tggactatcg accaaagaag cggtggaaac agccgtttca
    15541 gcaggagccg actatatcgg ttttgtcttt gcacctagta aaagacaggt gactttagaa
    15601 gaggcagctg agttggcaaa gcttattcct gcagatgtga aaaaggttgg agtatttgtt
    15661 tcaccaagtc gggtagaact gctggaagcg attgacaaag ttggcttgga cttggttcaa
    15721 gttcacggtc aggtggcagc tgatttattt gagaatttgc cttgtgccag tattcaggct
    15781 gtgcaggtag atggaaatgg gcatgtcccc aattctcagg cagattatct actctttgat
    15841 gcccctgtgg caggaagtgg tcagtccttt gattggggtc aactggatac gactggacta
    15901 gcacagccct tctttatcgc aggtggcctt aatgaagata atgtagtaaa agcaattcaa
    15961 cattttactc cctatgcagt agatgtatcg agcggagtgg agacagatgg acaaaaagat
    16021 catgaaaaga ttagaagatt tatagagagg gtaaagcatg gcatatcagg aaccaaataa
    16081 agatggattt tacggaaaat tcggcggacg ttttgtccca gaaacattga tgacagcagt
    16141 tttggagttg gagaaggcct accgtgaaag tcaggcagac ccaagtttcc aagaggaatt
    16201 aaaccagctt ttgcgccagt acgtaggacg tgaaactcct ctttattacg caaaaaactt
    16261 gacccagcat atcggcggag ccaagattta tctcaaacgg gaagacctta accatacagg
    16321 agcccacaag attaacaatg ccttgggaca agtttggctt gccaaacgca tgggtaaaaa
    16381 gaaaattatc gcagaaactg gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc
    16441 cctctttaac atggaatgta ccatctacat gggtgaggaa gatgtcaaac gccaagccct
    16501 caatgtcttc cgtatggagc ttttgggagc taaggtcgag gccgtgacag atggttcgcg
    16561 cgtgctcaag gatgcggtca atgcagctct tcgttcatgg gtggctaata tagatgatac
    16621 ccactatatc cttggttctg ccttggggcc tcatccattt ccagaaattg ttcgtgactt
    16681 ccaaagtgtc attggtcgag aggctaaaca acagtaccgt gacttgacag gacaaaatct
    16741 gccagatgcc ctagtagcct gtgttggtgg tgggtcgaat gccattggtc tcttccatcc
    16801 ctttgtagaa gatgagtcag tagccatgta tggagctgaa gcggctggac ttggtgtgga
    16861 tacggagcac cacgcagcta ccttgaccaa gggtcgtcca ggtgtccttc acggttccct
    16921 catggatgtg ctccaagatg cccatggtca aattcttgaa gccttctcta tctcagcagg
    16981 tttggactat cctggtatcg gtccagagca ttctcactac cacgatatta aacgtgccag
    17041 ctatgtccct gtgacagacg aagaagcctt ggaaggattc caactcttgt ctcgtgtgga
    17101 agggattatc ccagccttgg aatctagcca tgctatcgcc tttgcggtga aattggccaa
    17161 agaacttgga ccagaaaagt ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt
    17221 ggttcaagtc aaagaccgct tggaagcaga tgcagcaaag aagggagaag ctcatgccta
    17281 agacactaac aaaaaaatta aatgctatta aagcagctgg aaaaggaatt tttgttccct
    17341 atatcatggc tggtgaccac gaaaaaggtt tggatggtct tgctgaaaca attcactttt
    17401 tagaagattt gggtgtctct gcaattgaag tgggtattcc cttttcagac cctgttgcag
    17461 atggacctgt tatcgaagaa gctggcttgc gcagtttagc ccacgggacc tctacccagg
    17521 ctttagttga aaccttgaaa accattgaaa cagagattcc actggtcatc atgacctact
    17581 tcaaccccct ctttcagtac ggtgtggaga actttgtcaa agatctggct gatacagctg
    17641 tgaagggctt gattatccca gacctgcctc atgaacatgc caactttgta gaaccatttt
    17701 tggcagatac agatatcgcc ttgattcctt tagtaagctt gaccacagga attgagcgcc
    17761 agaaagagtt gattgaaggg gcggagggat tcgtctatgc cgttgccatc aatggggtaa
    17821 cagggaaatc aggcaattac cgtgcagatt tggacaagca cttggcgcaa cttcatcaag
    17881 tggccgacat cccagtcttg acaggttttg gtgtatctag tcaagccgat ctggaacgct
    17941 tcaatgcggt gtcagatggt gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag
    18001 gagagccgat tcaggacttt atcaaacaag cagtagctta ccaaaaataa ttaaacaagt
    18061 agcaagtaag aggaaaggca cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc
    18121 tagttttata gtgaattgaa tctggaatat tacactacgg ttcctaaaat attttaagaa
    18181 agtgatttga atttcccaat aaatttgttc agtttttaat tgattttact atagaagata
    18241 taattttcta aattactctg acacagaact ttaagaaaaa gctaattatt gtagtaattt
    18301 ctttaagaaa atgatataat tcattaaaaa gtatttggag gaggaagaat tatgttgaat
    18361 caggatctct ttgattcgct tgaggcacaa aaaattgtag atactttgat gaaagggcaa
    18421 aaagattatg tagatgaacg tctagaaaaa agagagacaa tgatagtgtc gaatggttat
    18481 gcatggacgt gacctaatca tattgatact gcatttgcat cagcagattt gtttgagtat
    18541 aaattacaat tagcaggaca gacttgggga tatttagaat ttgaaacaaa tacagaaaaa
    18601 tatgggaaag tattgttaat tataaagggt aagaagcgac ttacgaacca atttcctttg
    18661 gtacaaaaaa ataagagtgg ctacttattt gaatatgctc agatgaatac actttatctt
    18721 aatcaacatt cttcctacaa aaatgatgaa gatagtcatt cctttccaat tcagatggag
    18781 ttagtttctg atgaaatgat tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa
    18841 aaatttatga ttttaactta tgaggcggac tcagaaaaca atattatatc tgtagatgtt
    18901 gttatgcctg atgcacgaac tggtcagtta cacttgattc aagatttgtc tgagtatatt
    18961 caatcaagtt cgtaccattt cgaagaagct aaatatcaag atattcctaa tttttcagaa
    19021 ttatcggaaa cagaagattt tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag
    19081 tagtaaggaa tatgtaaatg tttaatggtc gggtattgaa agaattacgg ctgttaaatg
    19141 gtttaagtag agcagaatta gctcagagaa ttaatttaac ggaacaagcc atttggcagt
    19201 ttgagtccaa cgaaacgaaa cctaaattat caaccaaaat gcatttggcc aaccaatttc
    19261 atgttgattt aacttatttt gaacaggaag aagagagcat tcgatttgat tcttctgtaa
    19321 ttgcctttag aaatgcagac ctagcaacac ggaaaacaat agatattcaa actatgtatt
    19381 tacataaggt agatagtttg attgattatt ttgaaagttt tgtaattata cctaatatta
    19441 caattcatga cctaagtaat gtagtgagtg aatcttatca taagggagaa tccattgagg
    19501 aattggctct ttatgccagg gaaaaattag gtatttcaaa agataatcat gatttgcttt
    19561 ataaattaga acgttcaggc atctatatcg tggaacgatt aattaatggc caagctgatg
    19621 cttatagcgc atggtcaaaa ttgggaagac cttatattgt gttgggaacg aataaatcat
    19681 ctgtacgtcg aaattttgac ttagctcatg agctaggaca tattctttta cacaaatata
    19741 aagatatgaa tgaagatggc aatcgtttgg agcaagaagc aaattatttt gcatcatgtt
    19801 ttttattgcc aaaagaagag tttttagtca aatttgaaga gagggttggc aagcgtgtca
    19861 gcaatcctga tagttatatt ttattgaagt cggatttgaa tgtttcgata caggctttag
    19921 agtatcgagc ttttaagtta ggattattga ctccaaagca acattcttac ttttatcgtc
    19981 aaattgcgca aaaaggttac aaaatgattg aacctttgga tgatcaaatt tttgttaaaa
    20041 aaccaagcaa agtaaagagt attctggacg tcgttttgag taatcatcta gtcagtctag
    20101 cgactataat gtctaaacaa agtattcgtt tacagtttat aagcgaaata ttttcagtcg
    20161 aaatgaaatt ttttgatcag tatcaagaag atagaagaac agatcgattt gataacatca
    20221 tccctttgta caaaagaaat aatttataat ttaactgtga aataatttca tgaaggacat
    20281 atggcagaaa ttggatttta tcagacaagc agtagcttac caaaaataat cacacaagca
    20341 gcaagtaaga ggaaaggcac gaaaggaagt ctttcctttt tcttttgcag gagaaaggcc
    20401 agaatacccg tcgcagaagc gaactgaatc aagatcagta actccgttac gctaaagacg
    20461 agagcacaag aagctaaaaa gaggaaatct cctgcgccca tgcggatatc gataaaatga
    20521 gccaaaattc caagagcaag gaaggagacc atgaccagat tccagccaga ggaagctatt
    20581 aggattaggt ggaaagtcat ccagaccagt aagggatatt cctgatggcg aaagtcgtag
    20641 atgcctaagg tcaaaccagc ggtgattagg acgacttgcc ccaaggaaag caattcccaa
    20701 gagtaaagca gaaagaggag tcctaagact aattcaaaga gggcatacca gacaggatag
    20761 cgaactttgc agtagcgaca gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa
    20821 tctaagggac gcaagcgagt ctgacaggaa tcgcagtgac tggctgaact gataatggat
    20881 tgctctggaa aacggtcaat gaccaaacca agaaaggaag cgagaatgct cccgacgaga
    20941 aaaaaataaa aatcaatcat acttatctat tcgtaaaaaa tgggagaaat agtataatgg
    21001 agaaacatag ataagatggt gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta
    21061 tagaaaacgc tcagctcgta tgccaatggt ccaactcctt aggcaaagtc tttcaagaac
    21121 aatggatggg accaaggatt ccttttctac tgacccttca agccttggaa ggagtctttt
    21181 caatctttga tgaacaagag tttgtgggac ttatccagaa aatcaggcta gaagacagca
    21241 atcttcatat cgggagattt tttatcaacc cccagaaaca ggagcaaggc ttaggtagcc
    21301 aggctttaag gaaatttgtt agtttggcct ttgaaaatga agatatagat agtatttctc
    21361 taaatgtctt cgaggcaaat caaagagctc agaatcttta ccaaaaagaa ggatttgaaa
    21421 tcgttcaaat g
//
LOCUS       DBERAE010000037        21322 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.37, whole genome shotgun sequence.
ACCESSION   DBERAE010000037 DBERAE010000000
VERSION     DBERAE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.37"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            39..359
                     /locus_tag="ACL70N_001611"
                     /pseudo
     CDS             39..359
                     /locus_tag="ACL70N_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            480..1424
                     /gene="manA"
                     /locus_tag="ACL70N_001612"
     CDS             480..1424
                     /gene="manA"
                     /locus_tag="ACL70N_001612"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGS0590378.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1445..2791)
                     /locus_tag="ACL70N_001613"
     CDS             complement(1445..2791)
                     /locus_tag="ACL70N_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGS0590379.1"
                     /translation="MGVETWFYSSICWLAIGLGSVWKFPYMTAANGDGGFLLIFLIST
                     ILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGG
                     WILVYLGIEFGKLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKG
                     IERASKVMMPLLFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFF
                     ALSLGVTVMLTYASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGG
                     PSLLFIVLPQLFDKMPFGTIFYVLFLLLFLFAPVTFSVVMLEINVGNITNQDNSKRAK
                     WSVILGILTFVFGIPSALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALCLSLFTG
                     YIFKKALVMEELHLDERAWKQVLFQVWLFLLRFFVSSFQSSSWSSSPNLCNQKGLE"
     gene            complement(2710..2931)
                     /locus_tag="ACL70N_001614"
     CDS             complement(2710..2931)
                     /locus_tag="ACL70N_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGS0590380.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            3036..3785
                     /locus_tag="ACL70N_001615"
     CDS             3036..3785
                     /locus_tag="ACL70N_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGS0590381.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3805..4260)
                     /locus_tag="ACL70N_001616"
     CDS             complement(3805..4260)
                     /locus_tag="ACL70N_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS0590382.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4280..5455)
                     /locus_tag="ACL70N_001617"
     CDS             complement(4280..5455)
                     /locus_tag="ACL70N_001617"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0590383.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5514..6359)
                     /locus_tag="ACL70N_001618"
     CDS             complement(5514..6359)
                     /locus_tag="ACL70N_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0590384.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6484..7041
                     /locus_tag="ACL70N_001619"
     CDS             6484..7041
                     /locus_tag="ACL70N_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS0590385.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7060..7527
                     /locus_tag="ACL70N_001620"
     CDS             7060..7527
                     /locus_tag="ACL70N_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGS0590386.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7616..8245
                     /gene="upp"
                     /locus_tag="ACL70N_001621"
     CDS             7616..8245
                     /gene="upp"
                     /locus_tag="ACL70N_001621"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGS0590387.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8419..9009
                     /gene="clpP"
                     /locus_tag="ACL70N_001622"
     CDS             8419..9009
                     /gene="clpP"
                     /locus_tag="ACL70N_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGS0590388.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9088..9336
                     /locus_tag="ACL70N_001623"
     CDS             9088..9336
                     /locus_tag="ACL70N_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGS0590389.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9438..10598
                     /locus_tag="ACL70N_001624"
     CDS             9438..10598
                     /locus_tag="ACL70N_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0590390.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDSLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10866..11735
                     /locus_tag="ACL70N_001625"
     CDS             10866..11735
                     /locus_tag="ACL70N_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS0590391.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11739..12695
                     /locus_tag="ACL70N_001626"
     CDS             11739..12695
                     /locus_tag="ACL70N_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS0590392.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12695..13459
                     /locus_tag="ACL70N_001627"
     CDS             12695..13459
                     /locus_tag="ACL70N_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590393.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13459..14169
                     /locus_tag="ACL70N_001628"
     CDS             13459..14169
                     /locus_tag="ACL70N_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590394.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14477..15133
                     /locus_tag="ACL70N_001629"
     CDS             14477..15133
                     /locus_tag="ACL70N_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGS0590395.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15241..16336
                     /gene="prfB"
                     /locus_tag="ACL70N_001630"
     CDS             join(15241..15312,15314..16336)
                     /gene="prfB"
                     /locus_tag="ACL70N_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGS0590396.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16354..17046
                     /gene="ftsE"
                     /locus_tag="ACL70N_001631"
     CDS             16354..17046
                     /gene="ftsE"
                     /locus_tag="ACL70N_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGS0590397.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17039..17965
                     /gene="ftsX"
                     /locus_tag="ACL70N_001632"
     CDS             17039..17965
                     /gene="ftsX"
                     /locus_tag="ACL70N_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGS0590398.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18251..20431
                     /locus_tag="ACL70N_001633"
     CDS             18251..20431
                     /locus_tag="ACL70N_001633"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGS0590399.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20483..21298
                     /locus_tag="ACL70N_001634"
     CDS             20483..21298
                     /locus_tag="ACL70N_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0590400.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
BASE COUNT         6530 a         4016 c         4645 g         6131 t
ORIGIN      
        1 cactattata taatgctttt tgattttagt ttagtattat cgtagaaaat ggactcggtg
       61 ctatggatac accggatgag aatggttatg tagcagataa ctatcggatt acttacttag
      121 aggcccacat caaggccatg cgagatgcca tttaccaaga cggggttgac ttgcttggtt
      181 atacgacttg gggctgtatc gatctggttt cagctggcac aggggaaatg aataagcgct
      241 atggctttat ctatgtagat cgagataatg taggaaacgg agttctcaaa cgtagcaaga
      301 agaagtcctt ctattggtac aaggatgtca ttgatagcaa tggtgcaagc atcgggtaga
      361 gcacatttgt ttactatttt tataaaatct tctccctgct ttataagatg taaaaaagag
      421 ttcaattcga actctttttt tgctataatg aggggagaaa aatcagacag gagatcgaca
      481 tgtcagaacc attattttta caatcagtta tgcaagaaaa aatctggggt ggagccaagc
      541 tacgtgatga gtttggctac gacatcccaa gtgaaaaaat cggagaatat tgggccatct
      601 cagcccatcc aaatggagtc tctaaagttg ccaatggtcg ttacgaggga acagatcttg
      661 ctactttgta tgcggaacac cgtgaattat ttggcaatcg tccagaacct gtatttccac
      721 ttttgaccaa gatcctcgat gccaacgact ggctcagtgt ccaagttcac ccagacgatg
      781 cttatggact cgagcatgaa ggcgaactcg gaaaaacaga atgctggtac attatcgcag
      841 cggatgaagg ttcagagatt atctacggtc acaatgccaa gtcaaaagaa gaactccgcc
      901 agcaaatcga ggataagaac tgggatgcgc tgttgacaaa agtgccagtt aaagcaggag
      961 atttcttcta tgtaccaagc ggtaccatgc acgctatcgg ggcgggtatc ttgattcttg
     1021 aaacccagca gtctagcgat accacttacc gtgtctatga ctttgaccga aaggacgata
     1081 agggcaactt gcgtgaactt caccttgaaa aatctatcga tgtcttgaac attggtgaac
     1141 ccgcaaatag ccgtccagtg acaatcaaag cagatgatct acgttccact ctccttgtat
     1201 ccaatgattt cttcgcagtt tacaaatggg aaattactgg aaaagttaac tttgaaaaga
     1261 cagctgacta cagcttgttg agtgtcttgg ctggtcaagg tcaactaact gttgacggga
     1321 aaaactatcc aatccaaaaa gggagacact ttatcctacc aagtgatgtt gaatcttgga
     1381 ctttagaagg gcaagatttg gaattgattg ttagtcatcc ataaaaagaa agggcctgag
     1441 ttcactactc aagtcctttt tgattacata aattgggcga tgaagaccac gatgatgatt
     1501 ggaatgacga aacgaagaaa cgaaggagga agagccagac ttggaaaagt acttgtttcc
     1561 aggctctttc atcgagatgg agttcctcca taacaagagc ctttttaaag atatagcctg
     1621 taaaaagtga aaggcagaga gctccaaatg gcatgagaag attggaaacc aagaaatcca
     1681 tggcatcaaa gaaagtctta ccaaagatgt gaacatccgc cataactcca taggataggg
     1741 ctgaaggaat gccaaagaca aaggtcaaaa ttcctaaaat aacactccat ttggcacgtt
     1801 tgctgttatc ctggttggtg atattgccca cattgatctc cagcatcacg acagaaaaag
     1861 tgactggcgc aaaaaggaag agcaagagga aaaggacgta gaaaatggtt ccaaaaggca
     1921 tcttgtcaaa gagttgaggc aagacgataa agagcaagct cggtccccct tcagactgga
     1981 tattgaaggg ggaccgagct tggaaaatgg ctagacctgc catgatggat atcgagatat
     2041 tcatggctac gatggagatt cctgactgga ctaggttggt tttcttgtcc aagtaagaag
     2101 cataggtcaa catgactgta acccctagtg agagggcaaa gaaagattgt cccagagcat
     2161 agaggagacc agcgctagtc agttttgaaa agtctggttt gaggaagtaa agaacccctt
     2221 ccatggcatt tggcaaactg agagagcgac cgatgataac aacaaagatg ataaagagca
     2281 ggggcatcat gactttcgaa gctctttcaa tccctttttg aaccccacgt gatacaataa
     2341 agatatttaa taagataaag gctgcttgag ctcctagggc aatggctgga tttgaaatga
     2401 ttgaagtaaa taactgagca taatcacccg ttccaccaag ttggaacaat ttcccaaact
     2461 caatacctag atagactaga atccatcctc cgataacact gtaaaaagat aagaggataa
     2521 agagggcaaa ggcgccaatc caaccgataa agttgtactt gttattcttg cccagttttc
     2581 caaaggtttt gatagcggaa acgccagcac tacggccaag ggcaaactca gccagcagga
     2641 gagggaaacc gattaaaata gtggaaatga gaaagattag taaaaagcct ccatcgccat
     2701 tagcagcagt catgtaggga aacttccaaa cggaaccaag cccgatggcc agccagcaga
     2761 tgctagaata aaaccaagtt tcgaccccca ttgtgatttt tctgacatag ttaaactctg
     2821 atctcctttt tcaaaataag aaaaagctac ttgagttgtc aaatagcctt ctgtttgatt
     2881 gatagacttg actatcctat catgttttct aaggtctgtc aagaaaatca ttttcaagtt
     2941 ttcacacctt tctcaaaaaa gttaaaaaat tttctcaaaa acgcttgact ctgacctaag
     3001 gggaggggtt atactatcat tgtaaggagg aaatcatgta ccatataaaa gaagctgcgc
     3061 agctttcagg tgtctctgtc aagaccctgc atcactatga caagatagga ctcttggtcc
     3121 ccttaaagtc ggaaaacggc tatcgaacct acagtcaaga ggatttggaa cgccttcagg
     3181 tcattcttta ctacaaatat ctaggctttt ctttagagaa aatagcagag ctgttaaagg
     3241 aagaaaggac agatttattg ccccatttga ctaggcagtt ggactatcta actcgcgaaa
     3301 ggcaacatct ggataccttg atttccacct tgcaaaaaac tattcaagaa caaaaaggag
     3361 aaagaaaaat gaccattgag gaaaaattca cgggatttag ctatcaagac aatcaaaaat
     3421 accaccaaga agcggtagag aaatatggtc aagaagtcat gggacaagcg ctcgaacgcc
     3481 aaaaaggtca cgaagacgag gctacggccg cctttaacca agtctttcaa actttggcac
     3541 aaaatcttca agttggttta cctgcaacag caaccgaaaa ccaagagcaa gcagccaagc
     3601 tcttgcaagc cattcgcact tatggatttg actgctctat tgaggtattc ggtcatatcg
     3661 gtaaaggtta cgtctataac ccagagttta aggaaaacat tgacaagttt ggttctggaa
     3721 cagcccagta cacgtcagat gccattgcag cttacgttca gacaaatgca gaaaaaatag
     3781 gctaggaatt tcctagccta ttttttactt caaatcataa agccagtcgt caccgttttt
     3841 gtagtaaaag aattcactga gatcttcttc tagaaacaca cgaagcatat cagacatatc
     3901 atcggttgca agttttagat gagaaagatt ttcaaagtcc tcccaccaaa ctttcccttc
     3961 gtctgaagac tggagttcac cagtaaagtg ttctgtcttg taaaaaagga cgacataacg
     4021 ataatccttg tcgtcatacc agtttttgat accacagagt tggggtttgg aaatgatcag
     4081 accagtttct tctttcactt cacgaatgac agcatcgaca aaggattcgc cacgttcaac
     4141 atgaccacca ggaaaagtaa tgccaggcca gtcgggacta actcggtctt ggaccaggac
     4201 cttatctccg tttttaatca tacacatgtt aacaaattcg actgcctctc ttctgttcat
     4261 tcttcacaac ctttaatctt taatcataat gcagacttcc cgccacccag ccggtacaga
     4321 gggcagaagt gatgttaaag ccacccgtgt gggcattgat atccataact tcgcctgcaa
     4381 agtggaggcc aggtaccagc ttactttcaa gggttttagg attgatttcc ttgagactga
     4441 ctccaccctt ggtaacaaag gactttgcaa gggacatttt tccagttaca ggaattttaa
     4501 gttctttaat ggactggaca agctgttctc gttccttttc agtcagctgt ttgacttttt
     4561 caggatatcc ttgtacaaaa aattcggcca agcgttctgg taacaaggtt tttaaagcgt
     4621 ttttcaagga tttttcccga ttttcttcta gaaatgtaac caagtccttc tcagaaagtt
     4681 gaggcaaaac atcgagtgag agaacctccc cacctttgac aaagctagac atgcgtaggg
     4741 cagcaggacc tgacaaacca aagtgggtaa agagtaaatc atgagtgatg acatgcttac
     4801 cataacttag ggtcacatcg tccaaagaaa tcccttgtaa ggctttatgt ggaaaatctg
     4861 ttaataaagg actttcagca gcctcaagat cggtgatggt atgcttaaaa tggcgagcaa
     4921 tctcgtgacc aaaaccagtc gaaccagtcg aaggataaga cttaccacct gttgtgacaa
     4981 tgagtttctc acaagtgaag gtttgatccg ctgacttaag gacaaactgg ttatctactt
     5041 ttttaacaga aacgatttct atttgagtag caacttgacc acctagttcg gtgattttct
     5101 tttccaaagc ttcgataata gtccgagact tgtcactggc tggaaagacg cgtccgtggt
     5161 cttcgacctt aagtttaaca ccattttctg taaaaaagtt gatgatgtca tgattatcga
     5221 actgggagaa aacactgtaa agaaagcgtc cgtttccagg aattccagct agcaggttgt
     5281 ctaagctacc attgttggtc acattgcaac gtcccccacc agtcccagct aatttttttc
     5341 caagtttccg atttttttcg atgaggaggg ttttctgtcc ataaaagcta ctggaaatcg
     5401 tagccatcat accagcaggt cccccaccga tgacaatagt atcaaaatgt ttcatagctc
     5461 tattgtacca caaaaaaaca agagatgatg gtcacctctt gtcaagaatg caattaatca
     5521 atttcatagc ccatcagcaa accgccctct tctgcataga aactgcagag accagaggtt
     5581 ggtagaattt taatatccgc ttgtgggaag gtttcacgga ttcgctctga gagctgttga
     5641 caacattttt cgttattgcg ttgggccatg acaatacggc caccagcata tccagctttt
     5701 actaactcat cataggcagc ttgaactgat ttctttgatc cccttgcttt ttgtagcaat
     5761 tcgagagtcc cagtttcact agcttttccg accatacgaa tgttgagaag gccaacgacc
     5821 gtaccgataa gcttgctcaa acggccgttc ttcaccaagt tatcgacttt ggctaggaca
     5881 aagagcaact tagttttttc ttgataggcg gtgatagctt caaccacttc ttcaaaagac
     5941 aagccctggt caatcaagtc attcaatttt tctacgagta ggtcaacttc accaccagca
     6001 gataaactat caatcacatg aatcttagtg tcaggatggt cttccagata aatattcttt
     6061 gctagttgag cactattgtg actgccagaa agggtacctg tgatggttac taggaaaatg
     6121 tttttggcac cttcaaatgc tcgcaaatag tcatctgggc ttggacaagc tgattttgaa
     6181 gcttctgcag ttgcatacat ggtttccatc atttggtcaa tatcgagact ggcgtcatca
     6241 acaaagacct gatcagctac ttgaatggtt aaggggacac ttacaaaggt tgtgttaata
     6301 gctggtgttg gcagttgacg ataatcacaa ccagagtcag caataatctt ccaagtcata
     6361 gaaattctcc atctttgtca gttatacatt gacaaaggtt ctgtcttttt ttacaattat
     6421 atcatgaaaa ctcttgaaac aaaagcatca tccgtctgtt gtgacaagta gaaagaaaat
     6481 gttatgtctg aacgtagaat ctctgaaaag tctcttgaaa atctcagaaa atcaaatcaa
     6541 gaatccaatt tattaaccag agaagccatt gaaacagccc tcttgcaact cttggaaaaa
     6601 aaggagctga ccaagattag tatttctgaa ttggtcaaac gtgcaggtgt ttcgcgtgcg
     6661 gccttttatc gcaattatga ctccaaagag gaaattttag agagcgtctt taaacgaact
     6721 gtccacaata ttatggaaca gctgcatcat tacgatttaa agacagacct ttatttggtt
     6781 tgggttcacc ttttccggga ggccagaaag gaagctagag taattcaatt ggccttggat
     6841 taccatctgg aaaaaatctt tgtccaagcc atgcaggaat ttctagaaaa ataccatggg
     6901 aaatcaaaag gtgtcagctc ttatcttcat tccttctgga gctcagccat cgtctctgtc
     6961 cttctaaaat ggatcaagga tggcatgaag gtaccagctg aaaagattgc agatttaggt
     7021 ttaccatttt ttaaaaaata gagaaaaagg agaaaagaga tgactgaaaa aagactggcc
     7081 tgggatgagt attttgcagc ccaagcccta ctaattgcga atcgttccac ttgtaaacgt
     7141 gctaaagtgg gcgcgattct ggtaaaagat aataaggtta tttccactgg ttacaatggt
     7201 tcggtgtcag ggactgagca ttgtattgat cacgaatgtt tggtcattga aggccactgt
     7261 gttcgcaccc ttcacgctga ggtcaatgct atccttcaag gtgctgagcg tggtgttccc
     7321 aaaggcttta cagcctatgt aacccatttt ccttgtctca actgtacaaa acaattgctt
     7381 caggtcggct gcaagcgcgt ggtttatatc aaccagtacc gaatggacga ctacgcccaa
     7441 tacctttatc aagaaaaagg gacagaattg acccatttac cacttgagac agtacagaca
     7501 gctcttaaag aggctgatct aatgtaaaaa ttatcaaaaa taaatggttt agaaagattt
     7561 ttaaaccgtt ttttggtata atgagaagaa taaattgaaa gaaggaattc caaaaatggg
     7621 aaaaattgaa gttattaatc acccactgat tcaacacaaa ttgtcaatct tgcgtcgtac
     7681 agatacttct acaaaagctt ttcgtgagct agtagatgag attgcaatgt tgatggggta
     7741 tgaagtactt cgtgatcttc cactagaaga tgtggaaatc gaaacaccaa ttacaaaaac
     7801 agttcaaaaa caattggcag gtaagaaatt ggccatcgtc ccaatcttgc gtgcaggtat
     7861 cgggatggtt gatggtctct tgagcttggt tccagctgct aaagttggcc acatcggtat
     7921 gtaccgtgat gaagaaacac ttcaaccagt tgaatacttg gtgaaattgc ctgaggacat
     7981 tgaccaacgt caaatttttg tagtagaccc aatgttggca acaggtggct cagcaatctt
     8041 ggctgttgat tctcttaaaa aacgtggcgc atcaaatatc aaatttgtct gccttgtatc
     8101 tgctccagag ggtgtaaaag cccttcaaga agctcatcca gatgtagaaa tctttacagc
     8161 agccttggat gaacgtttga acgaacacgg ttatatcgtt ccaggtcttg gagatgctgg
     8221 agaccgcttg ttcggtacaa aataagatcg aaaagaagaa tgacttggaa aagtatttcc
     8281 agtcacgaaa ggaggttggg tttttgtttc tgtctaatga aagcagagca aaaatttgac
     8341 cttttttgac caagatatta taatagtctt atcttcagtc atttgaccaa caaaattaaa
     8401 actcaaaagg agaaatgaat gattcctgta gttattgaac aaacaagccg tggagaacgt
     8461 tcttacgata tttactcacg tcttctcaaa gaccgcatca ttatgctgac aggtccggtt
     8521 gaagacaata tggctaactc tgttattgcc caattgcttt tcttggatgc ccaagatagt
     8581 acaaaagata tttaccttta tgtcaataca ccaggtggtt ctgtttcagc tggtttggca
     8641 atcgtagata ccatgaactt tatcaaggca gatgtccaaa ccattgttat gggaatggct
     8701 gcatctatgg gaacagtcat cgcatcaagt ggagcaaaag gcaaacgttt catgcttcca
     8761 aatgctgaat acatgattca tcaaccaatg ggcggtacag gtggtggtac ccaacaaact
     8821 gatatggcta tcgctgcaga acacttgctc aaaactcgta ataccttgga aaaaatcttg
     8881 gctgaaaatt caggtcagtc aatggaaaaa gtccatgcag atgcagaacg tgataactgg
     8941 atgagcgccc aggaaacact tgaatatggc tttattgatg aaattatggc caacaattca
     9001 ttgaactaat gatgatagaa ggcaaactcg actgggtttg ctttttttgg tataataggg
     9061 agagatttct tagaaagagg atttatcatg tttgaaaaag tcaatcgctc tggcttgatt
     9121 atctatcttt actataatcg tgatgccaaa aaactgcagg attatggaga tattacctat
     9181 cattccaaga aacatcgtta cttacaactc tatgttccaa ctcaagaagt ggagcaattg
     9241 gtcggacgct tgagcaagga aaaatttatt aaaaaagtta gagtttgtca tatccaagag
     9301 ttggaaacac cctttgtggg caatctttat cgataggaaa acgttatcat cgaaaaagtt
     9361 caaggaaaac attgacaatt ttctgataat tcggtatatt cttaacagac tatttaagaa
     9421 ataaggagac aaaaaagatg aagaaaaaat ttgccctatc gtttgtggcg cttgcaagtg
     9481 tagcacttct tgcagcctgt ggagaagtga agtctggagc agtcaacact gctggtaact
     9541 cagtagagga aaagacaatt aaaatcgggt ttaactttga agaatcaggt tctttagctg
     9601 catacggaac agctgaacaa aaaggtgccc aattggctgt tgatgaaatc aatgccgcag
     9661 gtggtatcga tggaaaacaa atcgaagtag tcgataaaga taataagtct gaaacagctg
     9721 aggctgcttc agttacaact aaccttgtaa cccaatctaa agtatcagca gtcgtaggac
     9781 ctgcgacatc tggtgcgact gcagctgcgg tagcgaacgc tacaaaagca ggtgttccct
     9841 tgatctcacc aagtgcgact caagatggat tgactaaagg tcaagattac ctctttattg
     9901 gaactttcca agatagcttc caaggaaaaa ttatctcaaa ctatgtttct gaaaaattaa
     9961 atgctaagaa agttgttctt tacactgaca atgccagtga ctatgctaaa gggattgcca
    10021 aatctttccg cgagtcatac aagggtgaaa tcgttgcaga tgaaactttc gtagcaggtg
    10081 acacagactt ccaagcagcc cttacaaaaa tgaaagggaa agactttgat gctatcgttg
    10141 ttcctggtta ctataatgag gctggtaaga ttgtaaacca agcgcgtggc atgggaattg
    10201 acaaaccaat cgttggtggt gatggattca acggtgagga gtttgtacaa caagcaactg
    10261 ctgaaaaagc atcaaacatc tactttatct caggcttctc aactactgta gaagtttcag
    10321 ctaaagctaa agccttcctt gacgcttacc gtgctaagta caatgaagag ccttcaacat
    10381 ttgcagcctt ggcttatgat tcagttcacc ttgtagcaaa cgcagcaaaa ggtgctaaaa
    10441 attcaggtga aatcaaggat agccttgcta aaacaaaaga ttttgaaggt gtaactggtc
    10501 aaacaagctt cgatgcagac cacaacacag tcaaaactgc ttacatgatg accatgaaca
    10561 atggtaaagt tgaagcagca gaagttgtaa aaccataata gaaaaatgtt gaaataggga
    10621 atgagccttt gactcactcc ctgtttcgat atttaatact cttcgaaaat ctcttcaaac
    10681 tgcgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta tctacaacct
    10741 caaagcagtg ctttgagcaa cctgcggcta gtttcctagt ttgctctttg attttcattg
    10801 agtataagaa cctatcaaaa agtgagggaa aaccctcgga attataaata gaaagagtga
    10861 atcttatgct ccaacaactc gtaaatggtt tgattctagg tagtgtttac gcgctgttag
    10921 ccctaggata taccatggtt tacggaatta tcaagctcat caacttcgcc catggtgata
    10981 tttatatgat gggagccttt atcggttatt tcttgatcaa ttctttccaa atgaatttct
    11041 ttgtagcgct tattgtagct atgctagcga cagctattct tggtgtcgtg attgagtttc
    11101 ttgcttaccg acctttgcgc cactctactc gtattgctgt tttgattacg gctattgggg
    11161 tttctttcct attggagtat ggaatggtct atctggttgg tgccaatacc cgtgccttcc
    11221 ctcaagcgat tcaaacagtt cgatatgatt tgggaccaat tagcttaaca aatgtgcagt
    11281 taatgatttt ggccatttcc ttgattttga tgattttgtt acaagtcatt gtccaaaaga
    11341 ctaagatggg gaaagccatg cgtgcagtat cagtagatag cgacgcggcg caattgatgg
    11401 ggatcaatgt aaaccgtacg attagcttta ccttcgcttt gggttctgct cttgcgggtg
    11461 cggctggtgt tctgattgct ctttattata actctcttga gcctttgatg ggggttactc
    11521 caggtcttaa atctttcgtt gccgcagtac ttggtggtat cggaattatt cctggtgcgg
    11581 ctcttggtgg ctttgtgatt ggtctattgg aaacctttgc gacagccttt gggatgtcag
    11641 atttccgtga tgccattgtt tatggaatct tgttgttgat cttgattgtc cgcccagctg
    11701 gtatccttgg taagaatgtg aaagagaagg tgtaaacgat gaaggaaaat ttaaaagtta
    11761 atattctatg gttactcctt ttgttagctg gctatagctt gattagtgta ctggtttcag
    11821 tcggagtact taatctattc tatgtacaga ttttacaaca aattggaatt aatattattt
    11881 tggctgttgg tctcaactta atcgttggtt tttcaggaca attttcactt ggtcatgctg
    11941 gtttcatggc gattggtgcc tatgcagcag ctattattgg ttctaaatca ccaacctacg
    12001 gtgccttctt tggagctatg cttgtagggg ctttgctttc aggagcagtt gccttacttg
    12061 tcggcattcc aaccttgcgc ttgaaggggg actatcttgc ggtagcaact ctgggtgttt
    12121 ctgaaattat ccgtatcttt atcatcaatg gtggaagtct tacaaatggt gcggcaggta
    12181 tcttagggat tcctaacttt acaacttggc aaatggttta cttctttgtc gtgattacaa
    12241 ccattgcaac cttgaacttc ttgcgtagcc caattggccg ttcaaccctc tctgttcgtg
    12301 aagatgaaat cgctgctgag tcagttgggg ttaatacgac taaaattaaa atcatcgctt
    12361 ttgtctttgg tgccattact gcaagtattg ctgggtcact tcaggcagga tttatcgggt
    12421 ctgttgtacc gaaagattac accttcatca actcaatcaa cgttttgatt attgttgtat
    12481 ttggtggact cggttccatt acaggtgcga ttgtttcggc tattgttctg ggaattttga
    12541 atatgcttct ccaagatgtt gctagtgtgc gtatgattat ttacgctttg gccttggtat
    12601 tggtaatgat tttcagacca ggtggactcc ttggaacgtg ggaactgagc ctatcacgtt
    12661 tctttaaaaa atctaagaag gaggaacaaa actaatggca ttacttgaag taaaacagtt
    12721 aaccaaacat tttggtggtc taacagctgt tggagatgtg actcttgaat tgaacgaagg
    12781 ggaactggtt ggattaatcg gtccaaacgg agctgggaaa accacccttt tcaacctttt
    12841 gaccggtgtt tatgaaccaa gcgagggaac agtaacccta gatggtcacc ttttgaatgg
    12901 gaaatcacct tataagattg cctctttggg acttggacgt actttccaaa atatccgtct
    12961 ttttaaagat ttaacagttt tagacaatgt tttgattgct tttggaaacc atcacaaaca
    13021 gcatgttttt actagtttct tacgcttacc agctttttac aagagtgaaa aagaattaaa
    13081 ggctaaagct ttggaattgt tgaaaatctt tgatttagat ggtgatgcag agactcttgc
    13141 taaaaatctt tcctacggac aacaacgtcg tttggaaatt gttcgtgccc ttgctacgga
    13201 acctaaaatt ctcttcttag atgaaccagc agcaggtatg aacccacagg aaacagccga
    13261 attgactgag ttaattcgtc gtatcaaaga tgaatttaag attacaatca tgttgattga
    13321 acacgatatg aatctggtca tggaagtaac agaacgtatc tacgtacttg aatatggccg
    13381 tttaattgct caaggaactc cagacgaaat taagaccaat aaacgcgtta tcgaagctta
    13441 tctaggaggt gaagcctaat gtctatgtta aaagttgaaa atctttctgt gcattacggt
    13501 atgatccaag cagtccgtga tgtaagcttt gaagttaatg aaggagaagt tgtttccctt
    13561 atcggtgcca acggtgcagg taagacaact attcttcgca ccttgtcagg tttggttcga
    13621 ccaagttcag gaaagattga atttttaggt caagaaatcc aaaaaatgcc agctcagaaa
    13681 atcgtggcag gtggtctttc acaagttcca gaaggacgcc acgtctttcc tggcttgact
    13741 gttatggaaa atcttgaaat gggagctttc ttaaagaaaa atcgtgaaga aaatcaagct
    13801 aacttgaaga aggttttctc acgctttcct cgtcttgaag aacggaagaa ccaagatgca
    13861 gctactcttt caggagggga acaacaaatg cttgccatgg gacgcgctct tatgtcaaca
    13921 ccaaaacttc ttcttttaga tgaaccatca atgggacttg ccccaatctt catccaagag
    13981 atttttgata tcattcaaga tattcagaag caaggaacaa ccgtcctctt gattgaacaa
    14041 aatgccaata aagcactcgc aatctctgac cgaggatatg tattggaaac aggaaaaatc
    14101 gtcctatcag ggacaggaaa agaactcgct tcatcagaag aagtcagaaa agcatatcta
    14161 ggtggctaaa acaatccagt ggattgtttt agtcggcaga tgaagattac gaagtaatca
    14221 tcaatatagt ccgggggacc tttttagccg gtagattgag attgcaaaca aatctgcatc
    14281 tacattgaaa gcttaatttc taataattga aaaaatcgaa tgaaaagttt cttaccttca
    14341 ttcacagagc tcgattttag agctcttttt gctagcttat tcatactttt ctaaattttg
    14401 aaaaagaaat gtaagcgttt gatagatttg caaaaagatt gtataatagg gataagaata
    14461 gaaaaggaga agtctcatgg cagttaaaga ttttatgacc cgcaaggtag tttatattag
    14521 tccagataca acagtatctc atgcagcaga tttgatgaga gagcaaggat tgcaccgctt
    14581 gcctgttatc gaaaatgatc aattggttgg tttggtgact gagggaacca ttgcacaagc
    14641 aagtccatct aaagcaacaa gtctttctat ctatgagatg aattatcttc tgaataagac
    14701 aaaagtaaaa gatgtcatga ttcgcgatgt tgtcactgtc tcaggctatg ctagtctaga
    14761 agatgcaact tatctgatgt tgaaaaataa gattggtatt ctccctgtcg tagataacca
    14821 tcaagtatac ggagttatta ctgaccgtga cgttttccaa gcctttcttg aaattgcagg
    14881 ttatggcgaa gaagggattc gtgtacgctt tgttacagaa gatgaagttg gtgttcttgg
    14941 aaaaattatt tctttgattg tagaagaaaa tttgaatatc tcccatacag tcaatattcc
    15001 gcgtaaggat ggtaaggtca ttatcgaagt gcaaatcgat ggatcaattg atttaccagc
    15061 cttgaaagaa aaatttgaag caaatggtat tcaagtggaa gaaatcgctc gcacttcagc
    15121 aaaagtcttg taagaaggga agcccaaagg cttctttttt catgaaaagg ggattagagc
    15181 aaaagatgga aagaaatgat aaaatatgct ataatgaaat gatgtaaaaa aggagtattt
    15241 atggacattt cagtaattcg tcagaaaatt gacgcaaatc gtgaaaaatt agcttctttc
    15301 agggggtctc tttgacctcg aagggctaga ggaagagatt gccatcttgg aaaacaagat
    15361 gacagaacct gatttttgga acgataatat tgcggcccaa aaaacgtcgc aagaattgaa
    15421 tgaattaaaa aacacttaca ataccttcca taagatggaa gagttgcagg atgaagtcga
    15481 aattttattg gattttttgg ctgaagacga gtcagtgcat gatgaactgg tagcgcagtt
    15541 agccgaactt gataagataa tgaccagcta cgagatgact ctactcttgt cagaacctta
    15601 tgaccacaac aatgccatct tggaaatcca tccaggttct ggtggtactg aggcgcagga
    15661 ctggggtgat atgttgcttc gtatgtatac tcgttatggt aatgctaaag gctttaaagt
    15721 ggaagtgttg gattaccaag caggtgatga ggctggtatt aagtcggtaa ctttatcatt
    15781 tgaagggcct aatgcctatg gtctcctcaa gtcagaaatg ggtgttcatc gcttagtgcg
    15841 aatctcacca tttgactctg ccaaacgtcg ccatacctct ttcacatctg tagaagtgat
    15901 gccagaattg gatgatacta ttgaagtgga aatccgtgaa gatgatatca agatggatac
    15961 cttccgttca ggtggtgccg gtggacaaaa cgtcaataag gtttcaacag gtgtacgttt
    16021 aacccacatt ccaactggaa ttgttgtcca atcaacagtg gatcgtaccc agtatggaaa
    16081 tagagatcgc gccatgaaga tgttgcaggc taagctctat caaatggagc aagagaagaa
    16141 ggctgcggag gtagattctc tcaaaggtga gaaaaaggag atcacttggg gaagtcaaat
    16201 ccgttcttat gtcttcacgc cttatactat ggtaaaagat caccgaacta gctatgaggt
    16261 tgctcaggta gataaggtta tggatgggga cctagatggt tttatcgatg cttatctcaa
    16321 gtggcgaatt agctaagata gaaaggaact cacatgtcaa ttattgaaat gagagatgtc
    16381 gttaaaaaat acgacaacgg aacgactgct ctacgcggtg tttcggttag cgttcaaccg
    16441 ggggaatttg cttacatcgt aggaccttca ggagcaggga agtcaacttt tattcgttct
    16501 ctgtatcgtg aagtaaaaat cgataaagga agtctatcag ttgctggttt taatctggtt
    16561 aagatcaaaa agaaagatgt cccgcttcta cgtcgtagtg ttggggttgt cttccaagat
    16621 tataaactgt taccaaagaa aactgtctat gaaaatattg cttacgctat ggaagtaatc
    16681 ggggaaaatc gccgtaatat caaaagacga gtgatggaag ttttggactt ggttggattg
    16741 aagcataagg ttcgttcttt cccaaatgaa ctctcaggtg gggagcaaca gcggattgcg
    16801 attgcgcgtg caattgtaaa taatcccaaa gtattgatag ctgatgagcc aacaggaaat
    16861 ctggatccgg ataattcatg ggaaattatg aatctcttgg aacggattaa cctacaagga
    16921 acaactattt tgatggcgac tcataatagc cagattgtaa ataccttgcg ccaccgtgtc
    16981 attgccattg aaaatggccg tgtcgttcgt gacgaatcaa aaggagagta tggatacgat
    17041 gattagtaga ttttttcgcc atttatttga agccttaaaa agtttgaaac gaaatggttg
    17101 gatgacagta gctgctgtca gttcagtcat gattactttg accttggtgg caatatttgc
    17161 atctgttatt ttcaatacag cgaaactagc tacagatatt gaaaataatg tccgtgtagt
    17221 agtttatatc cgaaaggatg tggaagataa tagtcagaca attgaaaaag aaggtcaaac
    17281 tgttacaaat aatgactacc acaaggtata tgattctttg aagaacatgt ctacggttaa
    17341 aagtgttacc ttttcaagta aagaagaaca atatgaaaaa ttaaccgaga taatgggaga
    17401 taactggaaa atctttgaag gagatgccaa tcctctctat gatgcctata ttgtagaggc
    17461 aaacactcca aatgatgtaa aaactatagc cgaagatgct aaaaaaattg aaggtgtctc
    17521 tgaggttcaa gatggcggtg ccaatacaga aagactcttc aagttagctt catttatccg
    17581 tgtttgggga ctagggattg ctgctttgtt aatttttatc gcagttttct tgatttcaaa
    17641 taccattcgt attaccatta tttcccgcag tcgcgaaatt caaatcatgc gcttggtcgg
    17701 agctaaaaac agttatatcc gtggaccgtt cttgttagaa ggagccttta tcggtttatt
    17761 gggagctatc gcaccatctg ttttggtctt tattgtttat caaattgttt accaatctgt
    17821 caacaaatcg ttggtagggc aaaatctatc catgattagt ccagatttat ttagtccgtt
    17881 gatgattgcc ctactatttg tgattggggt tttcattggt tcattgggat caggaatatc
    17941 catgcgccga ttcttgaaga tttaggtaaa atagctgctt ttatgaggag attgtaaaat
    18001 ctcctttttt gctacaagag tttttgaaaa gagatgcgca gaagaaaaga gcttccaaag
    18061 aagtccccca gagaagactt cttgatggct aatttgaact tgaaatttgg cgcactagaa
    18121 attttttaga aaaaagtgta atttttttat aaaagccttt acaaaaaaaa ttaaagtggt
    18181 ataattaaat catagaaagt gcaaacgttt tcgtaaaacg tttgcctaaa taaaaataaa
    18241 ggagatttga atgatgaaag atacattcaa aaatgtcttg tctttcgaat tttggcaaaa
    18301 attcggtaag gctttgatgg tagttatcgc ggttatgccg gctgctggtt tgatgatttc
    18361 aatcggtaag tctatcgtga tgattaaccc aacctttgca ccacttgtca tcacaggtgg
    18421 aattcttgag caaatcggtt ggggggttat cggtaacctt cacattttgt ttgccctagc
    18481 cattggagga agctgggcta aagaacgtgc tggtggtgct ttcgccgctg gtcttgcctt
    18541 catcttgatt aaccgtatca ctggtacaat ctttggtgta tcaggcgata tgttgaaaaa
    18601 tccagatgct atggtaacta ctttctttgg tggttcaatc aaagttgctg attactttat
    18661 cagtgttctt gaagctccag ccttgaacat gggggtattc gtagggatta tctcaggttt
    18721 tgtaggggca actgcttaca acaaatacta caacttccgt aaacttcctg atgcactttc
    18781 attcttcaac gggaaacgtt tcgtaccatt tgtagttatt cttcgttcag caatcgctgc
    18841 aattctactt gctgctttct ggccagtagt tcaaacaggt atcaataatt tcggtatctg
    18901 gattgccaac tcacaagaaa ctgctccaat tcttgcacca ttcttgtatg gtactttgga
    18961 acgtttgctc ttgccatttg gtcttcacca catgttgact atcccaatga actacacagc
    19021 tcttggtggt acttatgaca ttttaactgg tgcagctaaa ggtactcaag tattcggtca
    19081 agacccacta tggcttgcat gggtaacaga ccttgtaaac cttaaaggta ctgatgctag
    19141 tcaataccaa cacttgttag atacagtaca tccagctcgt ttcaaagttg gacaaatgat
    19201 cggttcattc ggtatcttga tgggtgtgat tgttgctatc taccgtaatg ttgatgctga
    19261 caagaaacat aaatacaaag gtatgatgat tgcaacagct cttgcaacat tcttgacagg
    19321 ggttactgaa ccaatcgaat acatgttcat gttcatcgca acacctatgt atcttgttta
    19381 ctcacttgtt caaggtgctg ccttcgctat ggctgacgtc gtaaacctac gtatgcactc
    19441 attcggttca atcgagttct tgactcgtac acctattgca atcagtgctg gtattggtat
    19501 ggatatcgtt aacttcgttt gggtaactgt tctctttgct gtaatcatgt actttatcgc
    19561 aaacttcatg attcaaaaat tcaactacgc aactccaggg cgcaacggaa actacgaaac
    19621 tgctgaaggt tcagaagaaa ccagcagcga agtgaaagtt gcagcaggct ctcaagctgt
    19681 aaacattatc aaccttcttg gtggacgtgt aaacatcgtt gatgttgatg catgtatgac
    19741 tcgtcttcgt gtaactgtta aagatgcaga taaagtagga aatgcagagc aatggaaagc
    19801 agaaggagct atgggtcttg tgatgaaagg acaaggggtt caagctatct acggtccaaa
    19861 agctgacatt ttgaaatctg atatccaaga tatccttgat tcaggtgaaa tcattcctga
    19921 aactcttcca agccaaatga ctgaagtaca acaaaacact gttcacttca aagatcttac
    19981 tgaggaagtt tactcagtag cagacggtca agttgttgct ttggaacaag taaaggatcc
    20041 agtatttgct caaaaaatga tgggtgatgg atttgcagta gaacctgcaa atggaaacat
    20101 tgtatctcca gtttcaggta ctgtatcaag catcttccca acaaaacatg cttttggtat
    20161 tgtgacggaa gcaggtcttg aagtattggt tcacattggt ttggacacag taagtcttga
    20221 aggtaaacca tttacagttc atgttgctga aggacaaaaa gttgcagcag gagatctcct
    20281 tgtcacagct gacttgaatg ctatccgtgc agcaggacgt gaaacttcaa cagtagttgt
    20341 cttcacaaat ggtgatgcaa ttaaatcagt taaattagaa aaaacaggtt ctcttgcagc
    20401 taaaacagca gttgctaaag tagaattgta atatacttga ggttggaagc tgtattccaa
    20461 cctcttattt tgggagaaaa gaatgaaatt tttaacactc aatactcata gttggatgga
    20521 gaaagaagca gaggaaaaat tccagatttt gcttgaagat attcttgaaa aggactatga
    20581 tttgatttgt ttccaagaaa ttaatcagga gatgacctcg tcagaggtgg aggttaatga
    20641 cctttatcaa gctttgccag cagctgagcc tattcaccaa gatcactatg ttagactctt
    20701 ggttgaaaag ttatctgagc aagggaaaaa ttactactgg acctgggcct ataaccatat
    20761 cggctatgac cgctaccacg aaggtgtggc tatcttgtct aaaacaccta ttgaagccag
    20821 agaaattttg gtttcagatg tggatgatcc aacagactat catactcgcc gtgttgccct
    20881 agctgaaact gtagtcgatg gcaaggagct agcagttgcc agtgttcatc tctcttggtg
    20941 ggataaaggt tttcaagaag aatgggcacg atttgaggct gtcttgaaaa aattgaacaa
    21001 gccactttta ctagctggag attttaacaa cccagcaggt caggaaggtt accaagctat
    21061 tttagctagt ccattaggct tacaagacgc atttgaagtt gctcaagaga aaagtggtag
    21121 ctatactgtt ccgcctgaaa ttgatggctg gaaagggaac actgaacccc ttcgaatcga
    21181 ttatgtcttt actaccaaag agttagcggt ggaaaattta catgtcgtat ttgatggtaa
    21241 caagagtcca caagtgagtg atcactatgg cttgaatgct atgttaaact ggaaataata
    21301 actgaaaaga ggttggaact at
//
LOCUS       DBERAE010000038        21281 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.38, whole genome shotgun sequence.
ACCESSION   DBERAE010000038 DBERAE010000000
VERSION     DBERAE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.38"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            250..1695
                     /gene="cps4A"
                     /locus_tag="ACL70N_001635"
     CDS             250..1695
                     /gene="cps4A"
                     /locus_tag="ACL70N_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGS0590401.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1697..2428
                     /gene="cps4B"
                     /locus_tag="ACL70N_001636"
     CDS             1697..2428
                     /gene="cps4B"
                     /locus_tag="ACL70N_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGS0590402.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2437..3129
                     /gene="cpsC"
                     /locus_tag="ACL70N_001637"
     CDS             2437..3129
                     /gene="cpsC"
                     /locus_tag="ACL70N_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGS0590403.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            3139..3828
                     /locus_tag="ACL70N_001638"
     CDS             3139..3828
                     /locus_tag="ACL70N_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGS0590404.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            3844..5211
                     /locus_tag="ACL70N_001639"
     CDS             3844..5211
                     /locus_tag="ACL70N_001639"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS0590405.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5242..6414
                     /gene="cps2T"
                     /locus_tag="ACL70N_001640"
                     /gene_synonym="wchF"
     CDS             5242..6414
                     /gene="cps2T"
                     /locus_tag="ACL70N_001640"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HGS0590406.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            6411..7694
                     /locus_tag="ACL70N_001641"
     CDS             6411..7694
                     /locus_tag="ACL70N_001641"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0590407.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            7657..8361
                     /locus_tag="ACL70N_001642"
     CDS             7657..8361
                     /locus_tag="ACL70N_001642"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGS0590408.1"
                     /translation="MKGLQMIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSR
                     GLLRGIGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVK
                     IGDYSQIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAEN
                     HSYEVLHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPD
                     NVIIGGVPAKILMERK"
     gene            8405..9640
                     /locus_tag="ACL70N_001643"
     CDS             8405..9640
                     /locus_tag="ACL70N_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS0590409.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            9648..10772
                     /locus_tag="ACL70N_001644"
     CDS             9648..10772
                     /locus_tag="ACL70N_001644"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0590410.1"
                     /translation="MKKVLIVRSGPYQVNPEGYNLQELGLASAISQQGYQCDVMYYHK
                     TKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKFLNQYDKIIISEYSQIMAVL
                     LSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKRTKTVFCKTEKAECYLKNKG
                     FNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNILYVGSLSKRKNTAQLIRIF
                     NILKSKSGKKNELQLVLIGKDEDNIVEKINYSRFKDDIIYQPYLKNSQLQFIYPSSQL
                     LVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDGINGKIVNDFNDEHWVDCIE
                     NLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDER"
     gene            10781..11623
                     /locus_tag="ACL70N_001645"
     CDS             10781..11623
                     /locus_tag="ACL70N_001645"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0590411.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            11665..12933
                     /locus_tag="ACL70N_001646"
     CDS             11665..12933
                     /locus_tag="ACL70N_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HGS0590412.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTGFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            12926..13933
                     /locus_tag="ACL70N_001647"
     CDS             12926..13933
                     /locus_tag="ACL70N_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590413.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            13938..15380
                     /locus_tag="ACL70N_001648"
     CDS             13938..15380
                     /locus_tag="ACL70N_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGS0590414.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     gene            15383..16483
                     /gene="glf"
                     /locus_tag="ACL70N_001649"
     CDS             15383..16483
                     /gene="glf"
                     /locus_tag="ACL70N_001649"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HGS0590415.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPISDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            16510..17379
                     /gene="rfbA"
                     /locus_tag="ACL70N_001650"
     CDS             16510..17379
                     /gene="rfbA"
                     /locus_tag="ACL70N_001650"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGS0590416.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            17380..17973
                     /locus_tag="ACL70N_001651"
     CDS             17380..17973
                     /locus_tag="ACL70N_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGS0590417.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            17986..19035
                     /gene="rfbB"
                     /locus_tag="ACL70N_001652"
     CDS             17986..19035
                     /gene="rfbB"
                     /locus_tag="ACL70N_001652"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGS0590418.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            19101..19952
                     /gene="rfbD"
                     /locus_tag="ACL70N_001653"
     CDS             19101..19952
                     /gene="rfbD"
                     /locus_tag="ACL70N_001653"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGS0590419.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            20015..21098
                     /gene="glf"
                     /locus_tag="ACL70N_001654"
                     /pseudo
     CDS             20015..21098
                     /gene="glf"
                     /locus_tag="ACL70N_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         6976 a         3253 c         4435 g         6617 t
ORIGIN      
        1 aagattatac cacattgtgt actatattat attgaaacta gaatagtaca catctgcttc
       61 taaaatattg ttagaaaacg atttgactgt cctgatcaat ttgtcatgtt cttatttcat
      121 tttactatat ttttggttcg cgggaagtct actaagatac ttaaagatgc agatagtgaa
      181 aataaaggtg tagacattac cgtaaaaaag tgatataatc gtatgatgtt caatgtatag
      241 gtgttaatca tgagtagacg ttttaaaaaa tcaagttcac agaaagtgaa gcgaagtgtt
      301 aatatagttt tgctgactat ttatttattg ttagtttgtt ttttattatt cttaatcttt
      361 aagtacaata tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta
      421 gttgccttgg tagggctact cttgattatc tataaaaaag ctgaaaaatt tactattttt
      481 ctgttggtgt tctctatcct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtt
      541 ggactgacca atcgtttaaa tgcgacttct aattactcag aatattcaat cagtgtcgct
      601 gttttagcag atagtgagat cgaaaatgtt acgcaactga cgagtgtgac agcaccgact
      661 gggactgata atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc
      721 gatttgacga tcgaccagag ttcgtcttac ttggcagctt ataagagttt gattgcaggg
      781 gagactaagg ccattgtctt aaatagtgtc tttgaaaata tcatcgagtc agagtatcca
      841 gactatgcat cgaagataaa aaagatttat accaagggat tcactaaaaa agtagaagct
      901 cctaagacgt ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggc
      961 cctattagtt cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc
     1021 aagaaaatcc tcttgaccac aacgccacgt gatgcctatg taccaatcgc agatggtgga
     1081 aataatcaaa aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcac
     1141 accttagaaa atctctatgg agtggatatc aattactatg tgcgattgaa cttcacttct
     1201 ttcttgaaaa tgattgactt attgggaggg gtagatgttc ataatgatca agagttttca
     1261 gctctacatg ggaagttcca tttcccagta gggaatgtcc atctagactc tgagcaggct
     1321 ctaggttttg tacgtgaacg ctactcacta gccgatggag accgtgaccg tggtcgcaac
     1381 caacaaaagg tgattgtggc tatccttcaa aaattaacgt caaccgaagc actgaaaaat
     1441 tatagtacga tcattaatag cttgcaagat tctatccaaa caaatatgcc acttgagact
     1501 atgataaatt tggtcaatgc tcagttagaa agtggaggga attataaagt aaattctcaa
     1561 gatttaaaag ggacaggtcg gacggatctt ccttcttatg caatgccaga cagtaacctc
     1621 tatgtgttgg aaatagatga tagtagttta gctgtagtta aagcagctat acaggatgtg
     1681 atggagggta gatgaaatga tagacatcca ttcgcatatc gtttttgatg tagatgacgg
     1741 tcccaagtca agagaggaaa gcaaggctct cttggcagaa tcctacaggc aaggggtacg
     1801 aatcattgtc tctacctctc accgtcgcaa gggcatgttt gaaactccgg aagagaagat
     1861 agcagaaaac tttcttcagg ttcgggaaat agctaaggaa gtggcgagtg acttggtcat
     1921 tgcttacgga gctgaaattt actacacacc agatgttctg gataagctgg aaaaaaagcg
     1981 gattccgacc ctcaatgata gtcgttatgc cttgatagag tttagtatga acactcctta
     2041 tcgcgatatt catagcgcct tgagcaagat cttgatgttg ggaattactc cagtcattgc
     2101 ccacattgag cgctatgatg ctcttgaaaa taatgaaaaa cgcgttcgag aactgatcga
     2161 tatgggctgt tacacgcaag taaatagttc acatgtcctc aaacccaaac tttttggcga
     2221 acgttataaa ttcatgaaaa aaagagctca gtatttttta gagcaggatt tggttcatgt
     2281 cattgcaagt gatatgcaca atctagacgg tagacctcct catatggcag aagcatatga
     2341 ccttgttacc caaaaatacg gagaagcgaa ggctcaggaa ctttttatag acaatcctcg
     2401 aaaaattgta atggatcaac taatttagga gaaatgatga aagaacaaaa cacgatagaa
     2461 atcgatgtat ttcaattatt taaaaccttg tggaaacgca agctaatgat tttaatagtg
     2521 gcacttgtga caggtgcggg ggcttttgca tatagcactt ttattgttaa gccagaatat
     2581 acgagtacca cgcgaattta cgtagtgaat cgcgatcaag gagacaagcc ggggctgaca
     2641 aatcaggatt tgcaggcagg atcttatctg gtaaaagact accgtgagat tatcctttcg
     2701 cagaatgtat tggaaaaagt agcgacaaat ttgaagttgg atatgccaac aaaaacgtta
     2761 gccagcaaag ttaaagtgac tgtaccaact gacactcgta tcgtctcaat ctctgtcaaa
     2821 gataaacaac cagaagaagc cagtcgtatc gctaattctc tacgagaagt tgctgcagaa
     2881 aagatcgtcg ctgtaacgcg agtatctgat gtaacgacac ttgaagaagc gcgaccagct
     2941 acgactccct cttctccaaa tgttcgacgc aattccttgt ttggttttct tggaggagca
     3001 gtcgtaacag taattgctgt tcttttgatt gagttgctcg acacccgtgt gaaacgtcct
     3061 gaagatgtcg aagatgtact gcaaattcca cttttagggg tcgttccaga tttgaacaaa
     3121 atgaaatagg aggaagttat gccaacatta gaaatctcac aggcaaaatt ggattttgta
     3181 aaaaaggcag aggaatatta taacgctttg tgcacgaacc tacagttaag tggagatgat
     3241 ttgaaagtat tttctatcac ttctgtgaaa ctaggagaag gaaaatcaac gacttccacc
     3301 aatatcgctt gggcttttgc gcatgcaggt tacaaaacgc tgctgattga tggagatatt
     3361 cgcaattctg ttatgttagg tgtctttaaa gcaagggata agattacagg cctgacagaa
     3421 tttttatcag gaactacaga cctatcacaa gggctttgtg ataccaatgt cgaaaatctc
     3481 tttgtaattc aggctggctc tgtgtcaccg aatccgacag ctcttcttca aagtaagaat
     3541 ttcagtacaa tgcttgaaac cttgcgtaaa tattttgact acatcattgt agatactgct
     3601 cctgtcggtg tcgtgattga tgcggctatt attacgcgaa aatgcgatgc ttctatttta
     3661 gtgacggagg taggtgaaat aaatcgacgg gatattcaaa aagcaaaaga acagttggaa
     3721 cacacaggaa agccgttttt gggagttgtg ttgaataaat tcgatacttc agtagacaaa
     3781 tacggttctt atggaaatta tggagattac gggaaaaata aaaaataggt cgggggatta
     3841 gagatgaatg gaaaaatagt aaagtcttca ttggccataa tccagagttt tcttgttatt
     3901 ttattgactt atctacttag tgctgtgaga gaagcggaga ttgtttcaac aacagctatt
     3961 gcactttata tcctccatta ttttgtcttt tatatcagtg attatggaca ggatttcttt
     4021 aaaagaggat atttgattga acttgtccag acattgaaat atatcctatt ctttgcacta
     4081 gcgattagta tttctaattt tttcttagag gatcgattta gtatttccag acgaggcatg
     4141 atttactttc tcacattaca tgctctctta gtctatgtgc taaacctatt tatcaagtgg
     4201 tattggaagc gggcttatcc caactttaaa ggaagtaaga agattctcct acttacagca
     4261 acttctcgtg tcgaaaaggt actggataga ttaatagaat caaatgaggt tgttggggag
     4321 ttggtagccg tcagtgtctt agataaacca gattttcagc atgattgttt aaaggtagta
     4381 gcagaggggg agatagtaaa ctttgcgact catgaggtgg tcgatgaagt ctttatcaat
     4441 cttccaagtg aaaaatacaa tattggagag cttgtctctc agtttgaaac gatgggaatt
     4501 gatgtaacag ttaatctaaa tgcttttgat cgtagtttgg cacgtaacaa gcaaattcgt
     4561 gagatggcag gattaaacgt tgtgactttt tctacaacat tttataagac tagtcatgta
     4621 attgctaagc ggattattga tatcatgggt gcattggtag ggctgatact atgtggttta
     4681 gtcagtattg tactggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag
     4741 acgcgtatag gaaaaaatgg tcgtcagttc actttttata agtttcgctc tatgtgtgta
     4801 gatgccgagg cgaaaaaaag agaactcatg gaacaaaata ccatgcaggg tggaatgttt
     4861 aaggtggacg atgatcctcg tatcacgaaa attggttgtt ttatacggaa gactagcttg
     4921 gacgagctac cacagtttta taatgttcta aagggagata tgagtttggt tggcacacgg
     4981 ccaccaacag tggacgagta tgagcactat accccagaac aaaagcgtcg tctgagtttt
     5041 aaacctggca taacagggtt atggcaggtc agcggacgaa gtgagattaa gaattttgat
     5101 gaagttgtca aattagatgt agcctatata gacgattgga caatttggaa agatattgaa
     5161 attttattga agacagttaa agttgtattg atgaaggatg gagcgaagtg atttttgccc
     5221 ttcggtcttg ttaggagaga tatgaaacag tcagtttata tcattggttc aaaggggatt
     5281 cctgccaagt atggaggatt tgaaaccttt gttgagaaat taacagaata tcaaaaagat
     5341 ggtaacatcc aatactatgt tgcttgcatg cgcgaaaatt ctgcaaagtc aggatttaca
     5401 gcagacacat ttgagtacaa cggtgctatt tgttacaaca ttgatgtgcc taatattggt
     5461 cctgctagag ccattgctta cgatattgca gcggtcaata aggctattga attgtctaag
     5521 ggaaacaagg acgaggctcc cattttttac attctagctt gtcgtatcgg accttttatt
     5581 tctggactta agaaaaaaat tcgttcgatc ggaggccgtt tgctggtaaa tccagatggt
     5641 catgagtggc ttcgagctaa atggagcttg ccagttcgga agtattggaa attttcggaa
     5701 cagttgatgg tcaaacatgc agatttatta gtctgcgata gcaaaaatat cgaaaaatat
     5761 attcgagagg actataaaca gtatcagccc aagacgacct atatcgctta tggtacagat
     5821 actacccctt caagtctgaa atcagaagat gccaaagttc gaaactggta tcgtgaaaag
     5881 ggagtaagcg aaaatggcta ttatctagtg gtgggacgat tcgttcccga aaacaactat
     5941 gaaaccatga ttcgtgaatt tatcaagtct aagtccaata aggactttgt ccttattaca
     6001 aatgtggaac agaataaatt ttacgatcag ttgctcaagg aaacaggttt cgacaaggat
     6061 ctaagagtca aatttgtggg aacagtctat gaccaagaat tgctcaagta tatccgtgaa
     6121 aatgctttcg cctatttcca tggacatgaa gttgggggta ccaatccatc gcttcttgaa
     6181 gctttagcat ccactaaact caacttgttg ttggatgtcg gctttaaccg tgaagttggt
     6241 gaagacggag ccatttattg gaaaaaagat gagctagcgc atgtaatcga agaagtggaa
     6301 cgatttgatg aaggtgatat tacggaatta gacgaaaagt ctagccaacg aattgcggat
     6361 gcatttacgt gggaaaagat tgtgtcagat tatgaggaag tgtttactgt atgaaaattt
     6421 tgcattatac tttaggcttt caaccatcac gtacaggtgg tcttgtcaag tatgctgagg
     6481 atttgatgac tcaacaagct acagatggac atgaagtaat cgcattatat ccaggagaaa
     6541 tctcaattat atttaggcag gttagaataa aaaaagcaga gaatcgaaaa ttccaatgct
     6601 ataaaataat aaacagccta cccttggctc tatttggtgg tatttcagaa ccagatgaat
     6661 ttatgaagag ttgtgataaa gcttcttata ggaaattttt gaaaaatatt aaggtagatg
     6721 taattcacat tcactcgctt ataggattac ataaggaatt tattgaagtt gcaaaagaat
     6781 taggaattaa aactgtattt acaagccatg attattatgg tttagcgcca gttccgcatt
     6841 tttattttaa cggagtagat tatagtagta ataatactaa tttagcatgg aacatcatgt
     6901 cctctaatgc tcttagtgta aaaaaacttc gattctttca agtctctttt tacccaacaa
     6961 ttcggaaatt gatgaaaatg cttgggaaaa atccaaagtc caagaaaaac ttagtaattc
     7021 gtgatatcac ggaggctatt gattatagtg ctctccgctc ttattataaa gcaatgtttg
     7081 ggttaataga tgcttacctt ttcaatagtc agttagctaa ggaagtttat gaagctaatc
     7141 atataatacc taaaaacaat atcatagtgt ccatttctaa cagctcaata agtaatcata
     7201 atattcgtgt tagttccggt gagaaaacag tggtagctta tattgggcct gatgaggaat
     7261 ataaggggta ttttgatttt ctagatatag ttaatgattt agatcaggaa aagtatgata
     7321 ttaaaacata tggacatttt ccaaatgaag attgtccacc ttatatccaa cagaacggtt
     7381 atttcacaaa agacacggtt ggaagcgttt attccaatat agatattttg attgtgccga
     7441 gtaggtggaa ggaaacattt ggtttgatta gtatagaggc gctatcgtat gatgtgaatg
     7501 tttttgtgag caaaaatgtg ggctctaaag atttggtttc agaagaacat atctttcata
     7561 ataaagacga tttgttaaaa aaaattcaat atgtaaaatt cgagaatgta aaattcaaaa
     7621 cgatgaaaga gcatatggtg gagattataa attactatga aaggattaca aatgataatc
     7681 aaaagattaa ttaagacaat tacaggtaaa gaaattgatc ttcaccctga tatcccaata
     7741 acttacattc ttcagagagg ttttcaatac ggtttgggtc ttagtcgagg gttgttacgt
     7801 ggtattggtc taggaaaaaa aggcaaacga ttatttattg gacgtggggt aacccttctc
     7861 gcaaaacgca agttatatgt tggaaacaat atccgaatcg gcaaatatgt gagcatagat
     7921 tgcctttcaa aggatgggat ccaaattgcg gataatgtta agataggaga ttactcgcaa
     7981 ataattggta caggttcagt aaaaaatatg ggtattgggc tcaaaattgg aaagaactct
     8041 tctttctcag aatatagttt attcggttct gcaggtggga ttactatcgg aggagatgtt
     8101 attgctggac aaaatgtacg ttttcatgct gagaatcata gctacgaagt gttgcatata
     8161 ccaatcagag agcaaggtgt taatcgtaaa gggatatccg ttggtgacaa ttgctggatt
     8221 ggggcaggag ctgttttttt agatggatct agtatcggtt caggttgtat cgttgcaacg
     8281 aatgcggttg ttactaagaa atttccagat aatgtaatta ttggtggagt gccagctaaa
     8341 attttaatgg aaagaaagta gtattaaatt aattgtataa atggagggaa atgatatgtc
     8401 taaaatgaag attgctgtag ttgggacagg ttatgttggt ttatccattt ctgtgttact
     8461 tgcacaacac catcatgtag tagcagtaga tattgtaaaa gagaaagtag aattaattaa
     8521 taaaagaatt tcacctattc aggatgattt tattgaaaga tatctttcag aaagtaattt
     8581 agatttagtt gcaacaatag acgctgaaac agcttataaa gatgcctctt ttatcgtagt
     8641 agcgacacca acaaattatg acttagaaag aaattttttt gatacatcaa cagttgaatc
     8701 ggtcattcaa caagttcaga atatgaattc tacagcaact atagtaataa aatcaacagt
     8761 ccccgtgggc tttaccgatt caattcgtaa aaaattagga atttcaaatc ttctattcag
     8821 tcctgaattt ttgcgtgaat caagggcact ttatgataac ttatatccaa gtcggatcat
     8881 agttggaaca gatttaagta atcaaaaatt agttgaaaaa gcccaagttt tctctaatct
     8941 tttagtgcaa ggtgccatta aaaaagatat ccctatttta actatgggat ttactgaagc
     9001 tgaagcagtt aaattatttg ctaataccta cttagcattg cgggtatcat attttaatga
     9061 attagatact tatgcagaga tcaaagggtt agatactcaa aaaataattg aaggtgttag
     9121 tttagatcct cgtatcggaa cccattataa taatccgagc tttgggtatg gtggatattg
     9181 cttaccaaag gatactaagc aacttttagc caattataag aatgtcccag aagagcttat
     9241 tggagctata gtacgaagca atacaacacg taaagatttt attgctaatc aagttcttaa
     9301 agtggtgaat tataatatac cagaagacga tattcctact aaacagatgg agaaagaagt
     9361 tgttattgga atataccgat taactatgaa aagtaacagt gataactttc gtcagagttc
     9421 aatacaagga gttatgaaac gtattaagga tagaggagtt aaagtaatca tttttgagcc
     9481 tactctaaaa gatagtgata cattctttgg aaacgctgtt ataaatgatt tagaagagtt
     9541 caaagtaaag tgtgatgtga ttattgcaaa tcgttatgat gaaacgttga atgacgttaa
     9601 ggataaagta tatacacgag atatttttag aagagattga taaaaatatg aaaaaagtat
     9661 taattgttcg aagtggacct taccaagtca atccggaagg atataatctt caagaacttg
     9721 gtttagcctc cgctatcagt cagcaaggct accagtgtga tgtcatgtat tatcacaaaa
     9781 caaagaacta tgatcaatta tatgagaaaa atggggaaca aattaaaata ttctggagga
     9841 ggggaataag attatttaga agtggaattt atccccagat tttaagagag aaatttttga
     9901 atcagtatga taagataatt atttctgagt acagccagat tatggcagtt ttattgtcta
     9961 gaattcattc caatgtatat atttataatg gcccatacta taatctattt aagattccca
    10021 ttattgaacc tatatacgat tttctttttg tagaaatgct caataagaga accaaaacag
    10081 ttttctgcaa gacagaaaaa gcagagtgtt atcttaaaaa caaaggattc aatgattgta
    10141 aagtagtggg cgtaggtcta gatattgaga agtttgaaca agaagaggaa cctacagagg
    10201 atactataga gcttttaaga agaatggaga ataaacaaaa tattctttat gtaggttcac
    10261 tatcaaaaag aaaaaacaca gctcagttaa ttagaatttt taatatttta aaatctaaaa
    10321 gtggtaagaa aaatgaactt caattggtat tgattggtaa ggatgaggat aatattgttg
    10381 aaaaaattaa ctattcacgg tttaaagatg atattattta tcaaccttat ttaaagaatt
    10441 ctcagcttca atttatttac ccatcatcac aactacttgt gctcccgtca gttcaagaga
    10501 tttttggtat ggtattactt gaggcaatgt attttaagtt gcctgttgtt tccagtgcaa
    10561 gtgctggagg agagacactg attcaagatg gtataaacgg taaaattgtg aatgatttta
    10621 atgatgaaca ctgggtggat tgtatagaaa atctattaaa taacccattg gaattgaaac
    10681 ggcttggaga atgtgctcat aagcgcatta cggaacagtt tatgtggtct tcaattgcga
    10741 gaaaaataat tgagacattt gatgaaaggt aagacttgct atgaattttt gttttgtgat
    10801 tttgcattat cgtaccagca atgacactat agagtgtatc aaatcgattc aaaagcttga
    10861 gggagattat aaaattgtaa ttgttgataa tgcttctcaa aatggcagta tagaaagggt
    10921 agaagcctta tttgcaaata atgacgagat agttataata aaaaacacga aaaacttagg
    10981 atttgctgct ggaaataata ttggatacgc ctacgctagg actcaaataa aagctgatat
    11041 gattgctgta cttaataatg atattgttat taagcaaaaa gatttcatca atcgtatatt
    11101 tgaactctat agaaattctc agtttcatat cgctggtcca gacattgtct ctcttgtaga
    11161 tggtcatcat caaagtcctg ttgttgagaa gattaattct atatctaagg ctaataaaga
    11221 actttttaaa tatagaatct tgaggattat taataaaata ggattatatg agctgatgac
    11281 tagacagcca aaaaaagaat taaatagaat aagtgttgca gaccctatga gatatcagga
    11341 aaatgttatt ttacatggga gttttgtaat tttttcaccg ttgtatgttt cagaggagga
    11401 gtgtgctttc agaccggata cattcatgta tatggaagag cctattctat atgaatattg
    11461 catgcttaaa aattataaga cagtatttga tccttctatt gtaatttatc ataaagagga
    11521 ctcatcaaca aattcgttgt ataatgcagc atatgcaaaa agagagtttg tttttaaaaa
    11581 tatgattaga tctctaaaga tttatagaag tctattgaag tagtaaacta aggaaaggat
    11641 aataattaga aattgaatct tagtatgtta gccttgacaa taggaacagt ggtatttgtt
    11701 aaaaaaacgt ataggacgtt tctcaatccc ataattttat ttgtaatttt gtggtttatt
    11761 ataacaactt tgtcaagttt aaaactattc caacttttcg agattagtac tcacacacaa
    11821 caaattattt tgcttgggac ttctctattt gttatagggg gagggatagc aatttggttt
    11881 cgggataaat tttattttaa agttggcggt aactcatatt ttacaacagg ctttgaaatt
    11941 aattataatt tgttcttttt gctaggtatc atttgccttt tctattattt gccagatttc
    12001 ttttcctcac tggtatcatt aataagaggt gggaatttaa acttagttag acaatctgcg
    12061 caggatgcag tagataccag tggattaaag aatttcattg gaacatttat tgttagtcct
    12121 agtgccatgg tattagaaat attaggagta ttagatttct ggagcaataa aaaaggtaga
    12181 aaactatttt atcttagttt agctgtcatt tttgtaagag ttattgcaga tgctggtaga
    12241 acacctctat ttaatgttgt catatattta ttacttactg ttttagcaaa taggttctct
    12301 gaaaaaactg aaaagaagag aaaagttagt aaaattaaga tagtaaatta tggtatgcta
    12361 ggttcaatta tcttatggct atcaacttta tctaggacaa caacctccgt ttataggatt
    12421 ctttattttt atttcgcaat gtccccaata ttattagaaa agtggagtag tgtacttgat
    12481 tctgaaaaat tagtaacaaa gggtttggtt tcgttgaacg gtttcttttt ttcaatctca
    12541 tatgtactta aaaatctgtt tagaatagat tattcgcaaa gagtattaga agcatacaca
    12601 atgattgcga atactgatgc aatctggtat aatattgcac ctggtttgac caaggcaaat
    12661 gcatatgtct ctctgttttg gttcttttat gcggatggac gtttactagg agttttaata
    12721 ggatcccttc tatatggtac cttttgtggt tatatctttt gcaggtatat ccagcaacaa
    12781 aataaaaaga atttggctat gttactattt atttatcaag gtgttttttt ctcttttatt
    12841 agatttccgt tttcaaaatc aaattatgca attgcattcg tactcttatt attttttgct
    12901 tttaagaaga aaggaataga gaaaagtgtt taatatcaat gaccagtcta ttatttatgt
    12961 tgcatgtcct tattttaata aaacaggtgg aacggagctt gtccatcaat tagtttattc
    13021 tattaatcat tttgggggga aagctatcgt tgcttattat ggtagtgaaa gtgctccaaa
    13081 taaggtgaat cctgcgttta gagaatatgt ttctacgttt gttgatataa aagatgttat
    13141 tgactctctt gataatatta ttattttacc ggaaattaat ccggatttag ctgctaatct
    13201 agagtctatt caaaaagcag tatggtggat gagcgttgac aattatttga agcgtaatgg
    13261 tattttaggt tccttggaac attttggact tttacgaaca attaaattat ttgtaaaagg
    13321 aaatattaaa ataggtggat atagaataga taaagagatt ccccatcttt atcaaagtga
    13381 atacgccaag caatttcttc tagctaaagg tgtcaaaaag tactatagat tgtctgatta
    13441 tttaaacgag tcttatattc agcgatctat ttcaacagac actaaaaaag atgttattct
    13501 ttacaatcct aaaaaaggga ttgaatttac tcgtgagcta attaaacagg ctccagaatt
    13561 aacgttctct ccaattgaga atatgtcaac tgaacaggtg aaaaaattac tttcaaaaag
    13621 caaagtatat attgattttg gcaaccatcc tgggaaagat agattcccac gggaggcagc
    13681 gatatcaggt tgttgtgtga taactgggaa acgaggttct gcaaaatatt ataaggatat
    13741 tcctattcca gattcataca aatttgaaga cactgttgaa aatatcccca acattattga
    13801 gaccctgaaa tcatgcttaa aaaattatga caaacatact gttgactttg agaaatatca
    13861 acaatatatt aaatctgaac atgatttatt tgaaagagat gtgaaagaat tattcactag
    13921 gaataggggt taaggttatg tcaaccagaa attcacttat taaaaattct ctttataatg
    13981 ttgcttatag aatgttaaat atcatatttc cattagtatc cgcaacatat actgcacgga
    14041 taattttagc tagtggagtt ggggaggtct cgtttgcaca aaatgttgtt tcttacttta
    14101 caacgatagc tgctatgggt attccaaatt atggtatacg agaaattgct aaaactagaa
    14161 ataaagcaga ggctacgaat aaagtttttt cagagctatt tctgattaat ggattgtcta
    14221 cattactgtg ttctatagta tatttaattc tgattttgac attcaatagc atttttgata
    14281 atacatcaat gtatcttgct gtgggtttaa cattagtgtt taacttcctt aatatcgatt
    14341 ggttctatca aggaaaagag gactatgcat acatcacgaa acgtagtttc agtataaaac
    14401 ttatttctct ttttagttta tttatttttg ttagagatac tgacgatgca gttaactatg
    14461 cattgatttc tagcttagca attggcggga ataatatttt taatcttgtt aatttaagga
    14521 aatataatat tagatttagt tttaataata ttaagattag aagacactta aaacctattt
    14581 ttgttttgtt gggttcagtg attgctattg aaatctatac tatgctggat accactatga
    14641 ttggtgctat ggtaggaacg actgaggtag gttattatac aaattctatg aagctagtta
    14701 aattgctgat aactgtgatt accgctattg gaggagtgct tttaccacga ctaagtgatt
    14761 attattctaa gggagaattt gaaaaattaa atcacatcgt tgataaagtt tttagaatca
    14821 tgttgtttct ttttttacca gcccaagttg cattaattct agttgcacca gtaattatgc
    14881 cgattttatt tggtgatagt tttataccag cagtgttaac acttcaactt acttctttgc
    14941 ttatatgtac attagggttt agtaatttat ttgggactca aatattacta acatttggag
    15001 atgagcgaaa gcttttgatt agcacaattt taggagcgct tagtaatatc gctttgaacc
    15061 taattctgat tccagtaatg gctcaaaatg gagcagcgtt ggcatctgtg attagtgaaa
    15121 caattgttac tttaacagca tactactatg cgaaaaaacg tgtgacaatt aggtttgact
    15181 taggatttta tttgccaact gttgtttcaa caataatcat gggtggagct atatatgtag
    15241 taatgcaatt gtatattggg gatatagaaa aaatgttatt ttcaactttg ttaggaggtg
    15301 ttgtattcct tttaattaac gtttttatga agaatcctat tatatatgaa tttacaggta
    15361 ttataaagag aaagagataa ttatgtacga ctatttaatc gttggagcgg gtttgtctgg
    15421 agcaatcttc gcacacgaag ctacaaagcg tggaaaaaaa gtaaaagtga ttgataaacg
    15481 cgatcacatt ggagggaaca tatactgtga gaatgtagaa ggtatcaatg ttcataaata
    15541 tggtgcccat atcttccata cttctaataa aaaagtctgg gactacgtca atcaatttgc
    15601 tgagtttaac aactatatca actcacctgt cgcaaactat aagggaagtc tttataacct
    15661 tcctttcaat atgaatacct tctatgctat gtggggcaca aaaactccac aagaagtgaa
    15721 ggataagatt gctgagcaga cagctggtat gaaggatgtt gagccgaaaa atctggaaga
    15781 acaagctatc aagttgattg gtccggatat ctatgaaaag ttgatcaagg gttatacaga
    15841 aaagcaatgg ggacgctcag cgatagaact tcctccattt atcataaaac gccttccagt
    15901 tcgtttaacc tttgataata actattttaa tgaccgttac caagggattc ctattggtgg
    15961 ttacaatgtc atcatcgaaa atatgctgaa agatgtagaa gttgaacttg gagtagactt
    16021 ttttgctcat cgtgaagagt tggaagcatc tgctaacaaa gttgtcttca caggaatgat
    16081 cgaccaatat tttgactaca agcacggaga gttagaatac cgtagccttc gttttgagca
    16141 tgagatttta gacgaggaaa attatcaagg gaatgctgta gtgaactata cagagcgtga
    16201 gatcccttat actcgtatca tcgaacacaa acattttgaa tatggaatgc agccaaagac
    16261 agttatcacg catgaatatc cagctgactg gaagcgtggg gacgagccct actatcctat
    16321 tagcgatgag aaaaataatg ctatgtttgc taaataccaa gaagaagcag cgcagaatga
    16381 taaagttatc ttttgtgggc gtttagcaga ttataagtat tacgatatgc atgtggtgat
    16441 tgaacgggcg cttgaggttg tggagaaaga atttagtaat tgaaaaacaa cgaagaaagg
    16501 ttgcttatta tgaaaggtat tattctagca ggtggttcgg gaactcgctt gtatcctttg
    16561 actcgagccg catcaaaaca acttatgccg gtttatgata aaccgatgat ttactaccca
    16621 ctttcaacat taatgttggc tgggattagg gatattttga ttatctcaac tcctcaagat
    16681 ttgcctcgtt ttaaagagct tcttcaagat ggttccgagt ttggtattaa actttcttat
    16741 gctgagcaac caagtccaga tggtttggca caagccttta tcattgggga agagtttatt
    16801 tctgatgata gcgttgcgct aatcttaggt gataatatct accatggttc tgggctttcc
    16861 aagatgctac aaaaggcagc gagtaaggag tcgggagcaa ctgtttttgg ctaccatgtc
    16921 aaggatccag agcgctttgg tgtggttgag tttgatcagg atatgaaggc tatttctatt
    16981 gaagaaaagc cagagcaacc tcgttcaaac tatgcagtta caggtctcta tttctatgat
    17041 aatgatgtag tagagattgc caagagtatt aaaccaagtc ctcgtggtga actggaaatt
    17101 acagatgtaa acaaagctta cctagatcgt ggtgatttgt ctgttgagct tatgggacgt
    17161 ggctttgctt ggctggatac tggaactcat gaaagtttac tagaggcttc acagtacatc
    17221 gaaacagtcc aacggatgca aaatgttcag gtagcaaact tagaagaaat tgcctatcgc
    17281 atgggttata tcagtcgtga agatgtattg accttagccc aaccacttaa gaaaaatgaa
    17341 tacggacagt atctgctccg tttgattgga gaagcataga tgacagataa ttttttcggt
    17401 aagacgcttg cggcacgcaa ggttgaagct attccaggca tgttggagtt tgatatcccc
    17461 gttcatggag ataatcgtgg ctggtttaaa gaaaatttcc aaaaggaaaa aatgcttcca
    17521 cttggatttc cagagtcttt ctttgcagaa ggaaaattgc aaaacaatgt atccttctca
    17581 cgtaaaaatg tccttcgagg actccacgca gagccttggg ataagtacat ctctgtagca
    17641 gatggaggga aagttctggg ttcttgggtt gatctacgcg agggtgaaac ctttgggaat
    17701 acctatcaga cagtaattga tgcaagcaag ggaatctttg ttcctcgagg cgtagctaat
    17761 ggcttccaag ttctatcaga tacagtgtca tatagctatc tggtcaatga ttactgggct
    17821 ctcgagctca aacccaagta tgcctttgtg aactacgctg atccaagcct tggtattgaa
    17881 tgggaaaata ttgcagaagc agaggtttca gaagcagata aacatcatcc cctacttaag
    17941 gatgtaaaac ctttgaaaaa agaagatttg taaaaaggaa agaatatgac tgaatacaaa
    18001 aatattatcg tgacaggtgg agctggcttt atcggttcta actttgtcca ttatgtttac
    18061 gagaactttc caggtgttca cgtgacagtc ctagataagt tgacttatgc tggaaatcgc
    18121 gcgaatattg aggaaatttt aggtaatcgt gttgagttag ttgttggtga cattgctgat
    18181 gcggagttgg tagacaagtt ggctgctcaa gcagatgcta tcgttcatta tgcagcggaa
    18241 agccacaatg ataattcgct caatgatcca tcgccattta ttcatactaa cttcatcgga
    18301 acctatactc ttttagaagc tgctcgtaag tatgatattc gcttccacca tgtatcgaca
    18361 gatgaagttt atggggatct ccctttacgc gaagatttgc caggtcatgg tgaaggacca
    18421 ggtgagaaat ttactgctga aacaaaatac aacccaagct ctccgtactc atcaaccaag
    18481 gcagcctcag atttgattgt caaagcctgg gtgcgttctt ttggagtcaa ggcaacgatt
    18541 tccaactgtt caaataacta cggtccttat caacatatcg aaaaattcat cccacgtcag
    18601 attactaaca tcctaagtgg aattaagcca aaactttacg gtgaaggtaa gaatgttcgt
    18661 gactggattc ataccaatga ccattcttca ggagtttgga caatcttgac aaaagggcaa
    18721 atcggtgaaa cctacttgat tggggctgat ggtgagaaga acaataagga agttttggaa
    18781 cttatcctta aggaaatggg acaagctacg gatgcctatg atcatgtgac tgaccgtgca
    18841 ggacatgacc ttcgctatgc gattgatgcc agcaagctcc gtgatgagtt ggggtggaaa
    18901 cctgaattta ccaactttga agctgggctc aaggcaacaa tcaagtggta tacagataac
    18961 caagaatggt ggaaagcaga aaaagaagct gttgaagcca attatgctaa gactcaggag
    19021 attattacag tataaaaagc aggaaatagc tgctttttat tgctatattg agaagagtta
    19081 catattagaa aggtctagag atgattttaa ttacaggggc aaatggccaa ttaggaacgg
    19141 aacttcgcta tttattggat gaacgtaatg aagaatacgt ggcagtagat gtggctgaga
    19201 tggacattac caatgaagaa atggttgaga aagtttttga agaggtgaaa ccgactttag
    19261 tctaccactg tgcagcctac accgctgttg atgcagcaga ggatgaagga aaagagttgg
    19321 acttcgccat caatgtgacg gggacaaaaa atgtcgcaaa agcatctgaa aagcatggtg
    19381 caactctagt ttatatttct acggactatg tctttgacgg taagaaacca gttggacaag
    19441 agtgggaagt tgatgaccga ccagatccac agacagaata tggacgcact aagcgtatgg
    19501 gggaagagtt agttgagaag catgtgtcta atttctatat tatccgtact gcctgggtat
    19561 ttggaaatta tggcaaaaac ttcgttttta ccatgcaaaa tcttgcgaaa actcataaga
    19621 ctttaacagt tgtaaatgac cagtacggtc gtccgacttg gactcgtacc ttggctgagt
    19681 tcatgaccta cctagctgaa aatcgtaagg aatttggtta ttatcatttg tcaaatgatg
    19741 cgacagaaga cacaacatgg tatgattttg cagttgaaat tttgaaagat acagatgtcg
    19801 aagtcaagcc agtagattcc agtcaatttc cagccaaagc taaacgtccg ctaaactcaa
    19861 cgatgagcct ggccaaagcc aaagctactg gatttgttat tccaacttgg caagatgcat
    19921 tgcaagaatt ttacaaacaa gaagtgagat aagtagtaga atgattttct agtctaataa
    19981 aagaggcaga taatgaactc caaaggagct taagatgtac gattatcttg ttgttggtgc
    20041 agtctttgcc catgaagcag ccttagaagg aaaaaaagta aaagttattg aaaaacgaaa
    20101 tcatatcgcg ggtaatatct atactcgtga agaggaagga attcaagttc atcaatatgg
    20161 tgctcatatc ttccatactt ctgataagga gatctgggat tatgtaaatc agtttgcaga
    20221 gtttaaccgt tataccaatt ctcctgttgc aaactataag ggtgagattt ataaccttcc
    20281 ttttaatatg aataccttca ataaactctg gggagttgta acgccagcag aagtacaggc
    20341 taagattgat gaacaacgtg ctattttaaa tggtaaaact cctgaaaatt tggaagaaca
    20401 ggcgatttct cttgtaggta cagacatcta cgaaaaatta atcaaagact atacagagaa
    20461 acagtggggg caaaccaact actgaacttc catcctttat tattcgctgt ttaccagtac
    20521 acctgaccta tgataacaac tattttaacg atacctatca agggattcca attggtggat
    20581 acactcaaat agttgaaaaa tgttggatca tgaaaatatt gatgtagaaa caaatgttga
    20641 tttctttgtg aacaaagagc aatatctgaa agattttcct aagattgtct ttactggtat
    20701 gattgatgaa ttctttgact ataagttggg cgaactagag taccgtagtc ttcgttttga
    20761 aaatgagacc ttggatatgg aaaattacca aggaaatgca gttgtgaact atacggatgc
    20821 agaaacccca tatactcgca ttattgaaca caaacatttt gagtttggga gtcaagcaaa
    20881 gactatcatt actaatagaa cattctaaaa catgggaaaa aggtgatgag ccttattatc
    20941 cagttaataa tgatcgtaat aatcatttgt ataaatcata taaaaaactt gctgatgagc
    21001 aagggaatgt tatctttggt ggccgcttag gacactatcg ttattacgat atgcaccaag
    21061 taattggagc agctttgcag tgcgtgagaa atgagttaga ttcatactca atgaaaatta
    21121 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg
    21181 gaagctgacg cggtttgaag agattttcga agagtataaa caagtaaaac tgactaccag
    21241 ttattattta gaaatagtat taaaaattcc ttgactatat g
//
LOCUS       DBERAE010000039        20397 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.39, whole genome shotgun sequence.
ACCESSION   DBERAE010000039 DBERAE010000000
VERSION     DBERAE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.39"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            72..227
                     /locus_tag="ACL70N_001655"
                     /pseudo
     CDS             72..227
                     /locus_tag="ACL70N_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            427..3702
                     /gene="rexB"
                     /locus_tag="ACL70N_001656"
     CDS             427..3702
                     /gene="rexB"
                     /locus_tag="ACL70N_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGS0590420.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTDYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYCFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3699..7349
                     /gene="addA"
                     /locus_tag="ACL70N_001657"
     CDS             3699..7349
                     /gene="addA"
                     /locus_tag="ACL70N_001657"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGS0590421.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEVYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYIFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLTSLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7519..8697
                     /locus_tag="ACL70N_001658"
     CDS             7519..8697
                     /locus_tag="ACL70N_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590422.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERDIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8906..14980
                     /gene="iga"
                     /locus_tag="ACL70N_001659"
     CDS             8906..14980
                     /gene="iga"
                     /locus_tag="ACL70N_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGS0590423.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVSDKG
                     VPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSNKPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSN
                     QETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSG
                     NTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLEL
                     RNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKND
                     KILYKITAKVEKLQQEIESRYKDNFPFYLAKKGTEETTNFTSFSNLVKAINQNLSGTY
                     HLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEI
                     NLITPPIVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVK
                     ENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANL
                     AEYSIGDSGLLYTPNQFLYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELY
                     LEEQFTKTKEHLAENLKKLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERW
                     YNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLAS
                     HHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLN
                     SFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVA
                     DFDSPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVL
                     DPTTRFKDATDLQKYVHNMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDP
                     ADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTK
                     TINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFR
                     RSIFENKK"
     gene            15024..>20397
                     /gene="zmpD"
                     /locus_tag="ACL70N_001660"
     CDS             15024..>20397
                     /gene="zmpD"
                     /locus_tag="ACL70N_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HGS0590424.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVQPVLPEAVVAEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGA
                     NLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEVASEREELPS
                     LHTDIRTETIPKTTIEESDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVET
                     VTILKEMKPEIIVKGTKERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISS
                     IVAEIKDGDTVVKRVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERP
                     LRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTR
                     LTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFK
                     DLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPL
                     FQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGF
                     IDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAA
                     GIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMM
                     KVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEA
                     DTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFY
                     NKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDV
                     TKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMD
                     ARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKAL
                     VKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSS
                     ERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSE
                     PQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGK
                     YTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSG
                     IKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTN
                     MISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGAL
                     GLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGD
                     NSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTK
                     HGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYD
                     KGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKG
                     FTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFN
                     PLFKKDI"
BASE COUNT         6933 a         3732 c         4255 g         5477 t
ORIGIN      
        1 ccataagaag attataccac attgtgtcct atttttggtt cattttacta tagttcaatc
       61 attctatcaa gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg
      121 aattagagtc cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagacac
      181 tgggacaaca cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt
      241 gttaccgagg cttttttatt atatgatttt cagtggccag acttattcta tctaatacaa
      301 gtaaagctaa gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat
      361 tttaacagat ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag
      421 gctgagatga aattacttta tactgatatt cgaacttctt tgacagaaat tctaacaaga
      481 gaggcagaag agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt
      541 tcttttgaaa aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt
      601 accgtcacgc gctttgctca aatggctcgt tatctggtct tgaatgattt accagttaaa
      661 actactcttg atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat
      721 cccaaggact tgcgtgttta tggagctatt aagcaggatc ctcaattgat ccagcagtta
      781 attgagcttt accatgagat gaccaaatct cagatgaatt ttttggactt ggagaattta
      841 acagatgagg ataagagggc ggatttactc ttgatttttg agaaagtaac agactatctt
      901 aatcaaggtc agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat
      961 gacaaggtaa gtagtgattt taatcaaatc gccttggtca ttgacggctt tactcgtttt
     1021 tctgctgagg aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc
     1081 ggggcttatg ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa
     1141 gccagcgtaa aatttctcca tcatctggct tctaaatacc aaacgcccgc tcaggactgt
     1201 tctcaaactc atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct
     1261 tatgactttt cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc
     1321 tggtcttgtt tgacgcaaaa ggaggagttg gagctagtag cccgtagcat tcgtcagaaa
     1381 ttacatgaga actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct
     1441 tcttaccagt tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt
     1501 agaagcgaag ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta
     1561 aaacgttact gttttcgtca ggaggatttg attaatcttc ttagaactga cttgtatact
     1621 gacctcagtc agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat
     1681 ggcttgccag cctttcagca aatcttcacc aaatcccacc atggaaaatt taatcttgag
     1741 cgtttgaatg tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga
     1801 aaacaaaagg ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg
     1861 accaagcagt tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc
     1921 gaagtttgga aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca
     1981 caggttagtc tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac
     2041 cgtaccattc cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca
     2101 ttgactgctg actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct
     2161 caaaacacca gtcttctgac agatgaagaa aggcaaaatc taaaccaagc gaccgaagaa
     2221 ggcgttcaat tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt
     2281 tccttagtca attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa
     2341 agtgaaagta aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga
     2401 gagaagagga tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt
     2461 ttgtctagtc tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg
     2521 acttttgtca aggttctgtc gcgtgtcata ggtaaaaaac tagatcagca aggtctggaa
     2581 aatccagcca tcccaatcag tccaagcagc aagaccttag ccaaggacac cttgcaagct
     2641 ctctatcctg ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc
     2701 aatgaataca gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt
     2761 cctgatgccc gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttgcagttg
     2821 cctaatgaag attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa
     2881 cgcgaatttg aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg
     2941 cttgatgttg cacggacaac tggacatatt ctccgacaca atccagccat cgaaacaatc
     3001 aaagaagaag caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc
     3061 agtgtctttg tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata
     3121 ggagtagtag actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg
     3181 ctcaattctc agttaccaac ctatcttgct gccctaaaaa gagaagggga gcagaacttt
     3241 ttcggcgcca tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt
     3301 ctggcaggag cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa
     3361 aaagaaagca gttatttagg cgaattttat aacaaaaaca aggcgaatca actgacagat
     3421 gaggaatttc agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag
     3481 attttagcag gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca
     3541 tacgtccagc aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc
     3601 cgtttcctag aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag
     3661 caagcttggc ttgaaaaaat aagagaggag ttgaatcgat gaagcttatt ccctttttaa
     3721 gtgaggagga gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga
     3781 aaactgccga gcaaatcgaa gctatctaca cttctggcca gaatatcctg gtctcagcat
     3841 cggctggttc tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg
     3901 gtgtcgaaat ttctcaactc tttatctcaa cctttaccgt caaggctgca aatgaactta
     3961 aagaacgttt agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgacctca
     4021 aacaacactt gggacgccag ttggcagacc taccaaacgc tgccatcgga accatggact
     4081 ctttcacaca aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc
     4141 gtattttaca aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct
     4201 ttgaagcgca ttaccaaggt aaacagaaag agacctttag tcatttgctg aaaaactttg
     4261 ctgggcgtgg caaggacgaa cggggtctgc gccagcaggt ctataaaatc tatgacttcc
     4321 tccaatccac cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga
     4381 aagctgattt taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctttggg
     4441 atttggaaag ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg
     4501 cctatttaga aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagtccg
     4561 atagtcaggc ttatcaggca gtgcttgcgc gtgttgtcgc catctctaag gagaaaaacg
     4621 gtcgagctct gactaatgcc agtcgtaagg ctgatttgaa gcccctggct gatgcctaca
     4681 acgaagagag aaagacccag tttgctaaac taggacaatt atcagaccag ataaccattc
     4741 tcgactatca agaacgttat catcaagaca catgggaact agctaaaacc ttccaaacct
     4801 ttatgagtca ttttgtggag gtttatcgtc agcgcaaacg ccaggaaaat gcctttgaat
     4861 tcgctgatat cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt
     4921 cttatcagga gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc
     4981 aagaacggat gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca
     5041 agcaatccat ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac
     5101 gctatgcgca aaatccccaa gaaggcaagc tcattctcct caaggaaaat ttccgtagta
     5161 gttcagaagt gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg
     5221 gcgaaatcaa ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca
     5281 atccagacaa caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag
     5341 agagtcaaac agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga
     5401 aacttcatca agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca
     5461 gtcgtaatga ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg
     5521 gagagcaaaa caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg
     5581 tcattcacaa tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg
     5641 gttttgatga ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg
     5701 aaaatctcta tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga
     5761 ttcacacagc tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct
     5821 tgtatgccaa aacccattct ctctatgact tgatttggaa gatttacaac gaccgttttt
     5881 attatgacta tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc
     5941 tagcactgcg tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc
     6001 gtatgattga ccaagtctta gaagcccagc acgatttggc aagcgtagcc gtcgcaccgc
     6061 caaaagatgc agtagagctc atgaccatcc acaagagtaa agggctggag tttccttaca
     6121 tctttatcct caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc
     6181 tcagtcgtca gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag
     6241 aagaccacta tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg
     6301 aagaggaatt acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga
     6361 cgcgggctga gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaatcca
     6421 aggaataccc agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga
     6481 atttccaaga ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta
     6541 gttatcgttt tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca
     6601 agagtcctct ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag
     6661 ctctggaaat gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac
     6721 ttcctagtgt tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg
     6781 aaggtgtcga gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc
     6841 cagatttttc aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac
     6901 tcatgcagag aattgacctc agccagcaac taacccttac tagcctaaca gaaacactca
     6961 aacaagttca aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt
     7021 tctttgacac agcactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc
     7081 aacctttctc catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta
     7141 tccttgatgg ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc
     7201 gctatgatga accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag
     7261 aggctttatc acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta
     7321 aagacgaggt tcaagttgta aaagtataac ttatactctt cgaaaatctc ttcaaaccac
     7381 gtcagcttcg ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca
     7441 aaacagtgtt ttgagctgac tgcggctagc tttctagttt gctctttgat ttttattgag
     7501 tattagaaag gagacctcat gacacttcca gttagaaaat ccctgcacga tgcagtttta
     7561 caggcttcga aagcggatac ttgggaacaa gctaccaagg aatggaatga agtttccttg
     7621 atttttaacg gtatcggccg tagcaattgt gtctgtggaa atgccatcaa atacgcttat
     7681 gaactcttta acggtgtcac aggccaacgc ctctttccaa ttggtagcga ctgtgttcgt
     7741 cattttcatc gattgtccct tgaccagcaa ttggaagagg aagaaaaact gctcagaaag
     7801 gttgaaaatc taaccagaaa agctcagaaa aaggaaaaaa tcaaggtcaa taaaagtgac
     7861 tttgacgagc gacttctaaa atggctctgg gaaaaaggtg ttttcaaacc caatcgtggc
     7921 aatcaatttg cgcctgagag agactaccag cttttcctag aagtctttca gggaggaagt
     7981 tggaccaagg cggaaccaaa gaaaaaggct cggatggaag aagtccttga aaagtgtatc
     8041 aaaccctttt tacttgggaa atcggatgac caactctacc ttgtcaagct aggcaaggag
     8101 aaaattgact acgaacaaga actccgtatc caggcagaga aagaacgcaa gaagagggat
     8161 aaaatcgcca agcaatatgc agacaatctg gttctagcca tgggacccgc agagcgtgct
     8221 tatcaagatt actttggctt tacagagacc ctgactcaag aagaacgcaa gtgggaaaaa
     8281 attctttttg gtaaaaatag agcagaacgg gatatcaagg ccaaacaata ccaaaaagag
     8341 ctggaaaaag accaacgaat tgccagtcag gatccaattg aaagaaaaca gaagcagact
     8401 tggctcctca attcctattt tcgtgagctt cctgaagaaa aagctcgatt ttctaggctc
     8461 ttattagaat atcgaaaaag tggtgaagta cccttttcaa ctgaatacct gtccgatcat
     8521 ctcatcgact ttttctataa aatgaaagcc tttgaatttg aaatcgcacc agaacaagtc
     8581 cgagattttc taaaaaaaag cctgcaggaa gaccatcgct catcagcaca aggaagctgg
     8641 atagaaggaa ttctcctcaa ctgcctcaaa ccatttttag aacgattagt gatatgagta
     8701 acacctaccg tgtaaatttc atggtaggtg ttattgtacc tcaaaataat ataaaacaaa
     8761 gtatgaaagc gcatctcaat tttaagactt ttttgtaaat taagagtata attaaggtat
     8821 actgcctttt ctatagataa tatataatac actaatataa taaaggtctt tgtaacatat
     8881 ataaatttta tttcaaggag gaataatgga aaagtatttt ggtgaaaaac aagagcgttt
     8941 ttcatttaga aaattatcag taggacttgt atctgcaacg atttcaagtt tattttttat
     9001 gtctgtatta gctagttcat ctgtggatgc tcaagaaact gcgggagttc actataaata
     9061 tgtggcagat tcagagctat catcagaaga aaagaagcag cttgtctatg atattccgac
     9121 atacgtggag aatgatgatg aaacttatta tcttgtttat aagttaaatt ctcaaaatca
     9181 actggcggaa ttaccaaata ctggaagcaa gaatgagagg caagccctag ttgctggtgc
     9241 tagcttagct gctctgggaa ttttaatttt tgctgtttcc aagaaaaagg ttaagaataa
     9301 aacggtatta catttagtat tggttgcggg aataggaaat ggtgtcttag tttcagtcca
     9361 tgctttagaa aatcatcttt tgctaaatta caatacggac tatgaattga cctctggaga
     9421 aaaattacct cttcctaaag agatttcagg ttacacttat attggatata tcaaagaggg
     9481 aaaaacgact tctgattttg aagtaagtaa tcaagaaaaa tcagcagcca ctcctacaaa
     9541 acaacaaaag gtggattata atgttacacc aaattttgta gaccatccat caacagtaca
     9601 agctattcag gaacaaacac ctgtttcttc aactaagccg acagaagttc aagtagttga
     9661 aaaacctttc tctactgaat taatcaatcc aagaaaagaa gagaaacaat cttcagattc
     9721 tcaagaacaa ttagccgaac ataagaatct agaaacgaag aaagaggaga agatttctcc
     9781 aaaagaaaag actggggtaa atacattaaa tccacaggat gaagttttat caggtcaatt
     9841 gaacaaacct gaactcttat atcgtgagga aactatagag acaaaaatag attttcaaga
     9901 agaaattcaa gaaaatcctg atttagctga aggaactgta agagtaaaac aagaaggtaa
     9961 attaggtaag aaagttgaaa tcgtcagaat attctctgta aacaaggaag aagtttcgcg
    10021 agaaattgtt tcaacttcaa cgactgcgcc tagtccaaga atagtcgaaa aaggtactaa
    10081 aaaaactcaa gttataaagg aacaacctga gactggtgta gaacataagg acgtacagtc
    10141 tggagctatt gttgaacccg caattcagcc tgagttgccc gaagctgtag taagtgacaa
    10201 aggcgaacca gaagttcaac ctacattacc cgaagcagtt gtaagcgata aaggcgtacc
    10261 agaagttcaa cctgaattac ccgaagcagt tgtaagcgat aaaggcgtac cagaagttca
    10321 gcctgaatta cccgaagcag ttgtaagtga taaaggtgaa ccagagcagg tagcaccatt
    10381 gccagaatat aaggggaata ttgagcaagt aaaacctgaa actccggttg agaagaccaa
    10441 agaacagggt ccagaaaaaa cggaagaagt tccagtaaaa ccaacagaag aaacaccagt
    10501 aaatccaaat gaaggtacta cagaaggaac ctcaattcaa ggagcagaaa atccagttca
    10561 acctgcagaa gaatcaacaa cgaattcaga gaaagtatca ccagatacat ctagcgaaaa
    10621 tactggggaa gtatccaata aacctagtga ttcgacaacc tcagttggag aatcaaataa
    10681 accagaacat aatgactcta aaaatgaaaa ttcagaaaaa actgtagaag aagttccggt
    10741 aaatccaaat gaaggcacag tagaagggac ctcaaatcaa gaaacagaaa aaccagttca
    10801 acctgcagaa gaaacacaaa caaactctgg gaaaatagct aacgaaaata ctggagaagt
    10861 atccaataaa cctagtgatt caaaaccacc agttgaagaa tcaaatcaac cagaaaaaaa
    10921 cggaactgca acaaaaccag aaaattcagg taatacaaca tcagagaatg gacaaacaga
    10981 accagaacca tcaaacggaa attcaactga ggatgtttca accaaatcaa acacatccaa
    11041 ttcaaatgga aacgaagaaa ttaaacaaga aaatgaacta gaccccgata aaaaggtaga
    11101 agatccagag aaaacacttg aattaagaaa tgtttccgac ctagagttat acagtttgtc
    11161 aaatggtact tataaacaac acatttcgtt agagcaagtt ccaagcaatc caaatagcta
    11221 ctttgttaaa gtgaaatctt cttcattcaa agatgtatac ctaccagtag catcaatatc
    11281 agaggaaaga aaaaatgata aaatccttta taaaatcaca gcaaaagtag agaagcttca
    11341 gcaggagata gaaagcagat ataaagataa ttttcccttc tatctagcta agaagggaac
    11401 agaagaaaca acaaacttta cttcctttag taatctggtc aaagctataa accaaaatct
    11461 ctctggaacc tatcatttag gagctagcct gaatgctaac gaagtggagc ttagtactga
    11521 tgataaatcc tatatcaagg gaacctttac tggtcagttg attggtgaaa aagatggtaa
    11581 gcattatgct atttacaact tgaaaaagcc tctttttgaa aacttgagtg gtgctacagt
    11641 agaaaaactg agtctaaaaa atgttgctat ttcagggaaa aatgatattg gttcactggc
    11701 aaatgaagct acgaatggca caaagattaa acaagttcat gttgatggtg ttctggctgg
    11761 agaacgtggt gtcggtggtt tgttggctaa ggcagaccaa tcaagcatcg cagagagcag
    11821 tttcaaggga agaattgtca atacctatga aacgactgat tcctacaata ttggcggtct
    11881 ggtcggtcat ttaacaggaa aaaatgcgtc tattgctaaa tccaaagcga cagtaaccat
    11941 ttcgtcaaac accaataggt cagatcagac tgtcggtggt cttgcaggtc tagtagaccg
    12001 agatgcacag atccaagata gctatgctga aggtgatatc aacaatgtca agcactttgg
    12061 tagagtcgct ggagtggcag gcaatttgtg ggatcgaact tctggtgatg ttaggcatgc
    12121 tggaagtttg accaatgttc tcagcgatgt taatgtaaca aacggaaatg ccatcactgg
    12181 ataccactat acaggaatga aggtagctaa tacatttagt agtaaggcta atagagtttt
    12241 caatgtcact ttagagaaga atgaggtcgt cagcaaagaa tccttcgagg aaagaggaac
    12301 aatgctagat gcttctcaaa ttgcaagcaa aaaagcagaa atcaatctta tcactccacc
    12361 aatagtggaa cccctctcaa caagcggtaa gaaagacagt gatttttcta agatagccca
    12421 ttatcaagcc aaccgtgctt tggtttataa gaacattgaa aaattgttac ctttctataa
    12481 caaggcgacc atcgtgaaat acggaaacct ggttaaggag aacagtatct tatatcaaaa
    12541 agaactcttg tctgcagtta tgatgaagga tgaccaagta atcacagata ttatttccaa
    12601 caaacagact gcaaacaaac tcttgcttca ctacaaggac cattcatctg aaaagtttga
    12661 tctcaggtac caggctgatt ttgccaattt ggcagaatat agcattggag atagtgggct
    12721 tctctatacg ccaaatcaat tcttgtatca tcaagattct attattaacc aagtgctgcc
    12781 tgaattgaat cgagtaaatt atcaatcaga tgctgttaga aatacacttg gaatttcacc
    12841 agaagtgaag ctaacggagt tatatcttga agaacaattt accaaaacga aagagcatct
    12901 agcagagaac ttgaaaaaac ttttatcatc tgatgcaggt ttagtaacag acaatgaagt
    12961 tatgacagga tatataatag ataaaattaa acggaataag gaagccttac ttcttggaat
    13021 gagttattta gaacgttggt ataactttag ctatggtcaa gtgaatgtca aagacctagt
    13081 tatgtatcat ccggacttct ttggtaaagg aaatacttca ccattagata ctctgattga
    13141 gttaggtaaa tctggcttta acaatcttct tgctaaaaac aatgtcgata cttatgctat
    13201 cagccttgcc agccatcatg gaacgacaga tttgtttagc acgttggaaa attaccgaaa
    13261 agtctttcta ccagataaaa ccaataatga ctggtttaaa tcacagacta aggcttacat
    13321 tgtcgaagaa aaatccaata tcgaagaggt gaaaacgaag caaggactag ttggcactaa
    13381 gtattctatt ggtgtctatg accgtatcac tagtgccaca tggaaatacc gtaatatggt
    13441 actacctcta cttaccttgc cagaaagatc cgtatttgtc atttcaacca tatctagtct
    13501 aggttttggt gcttatgatc gctatcgtaa taaagaacat caagcaaatg gtgatcttaa
    13561 tagctttgtt gaaaagagtg ctcacgaaac agcagagcgt caacgagatc actatgatta
    13621 ttggtatcgt attctagatg aaaaagggcg tgaaaagctt tatcgaaata tcttgcttta
    13681 tgatgcctat aaatttggaa ctaatcatac tgaaggaaag gctacagaag tagcagattt
    13741 tgatagtcca aatcctgcaa tgaaacattt ctttggacct gttggaaata aggttggaca
    13801 taatggacat ggtgcttatg ctacagggga tgcagtatat tatatggggt atcgcatgct
    13861 agataaggat ggagctatta cgtatactca tgagatgacg cataattcag atcaagatat
    13921 ttatcttggt ggttatggaa gaagaagtgg acttggacct gagttctttg ctaaaggctt
    13981 actacaagca ccagaccaac caagtgatgc aacgattact atcaattcta tattgaaaca
    14041 ttcaaaatct gatagtaaag aaggagaacg attacaagta cttgatccaa ctacgagatt
    14101 taaagacgca acagatcttc aaaaatacgt ccacaatatg tttgatgttg tttatatgtt
    14161 ggaatatctc gaaggtaaat ctattgttaa gaaattaaat gtatatcaga aaatagaagc
    14221 tctcagaaaa atcgagaacc aatatctaac agatcctgct gatggaaatg atgtttatgc
    14281 tactaatgtt gtgaaaaatt tgactgaaga tgaagctaaa aaattgacga gctttgatag
    14341 tttgattgac aataacattc tttcggctcg tgagtataag gctggcactt atgagagaaa
    14401 tggctacttt actataaaac tctttgcacc aatcttttca gcattgagcg gtgagaaagg
    14461 aactccaggt gaccttatgg gacgaaggat agcttttgaa cttctagctg ctaaaggatt
    14521 taaagatggt atggtaccat atatttccaa ccaatacgaa gaagatgcta aacaacaagg
    14581 gcaaactatc aatctttatg gtaaagaacg gggcttggtg accgatgagc ttgttttgaa
    14641 aaaggtattt gatggtaagt ataaaacttg ggcagaattt aagacagcta tgtaccaaga
    14701 acgggtggat cagtttggaa acttgaagca ggtgaccttt aaagatccga caaaaccatg
    14761 gccaagatat ggcacaaaga ctatcaataa tgtggatgaa ttgcagaaac taatggatga
    14821 agctgttttg caggatgcaa aagaacgtaa ttattattat tggaataact ataatccaga
    14881 aacggacagt gccgtccata agttgaagag agcaatcttt aaagcctatc ttgaccaaac
    14941 aaatgatttt agaagatcaa tttttgagaa taaaaaatag tgtttactat taggaaataa
    15001 aaagtgaatg tggaggatta gaattgtcat tattaaaaaa agataaattt tccattcgga
    15061 aaataaaggg tattgttggt tcggtattct tggggagtct tttatttgca ccgtcagttg
    15121 ttggtacatc gacttatcat tacttagatt atagtacttt gacacaaact gaacgtgttc
    15181 aactcaaaca aggtagacct gatgaatcaa aagagtcata tgctttggtt tatgaaaaag
    15241 acgcattacc aaacacagga agttctcaat ctattatgac tgcattgggt ttgttagcta
    15301 tcgggagtct tattgtgatt atcacaaaag ataaaaagag gaaaaaaatc gctacatttt
    15361 tgattgtagg ggcgacaggt ttagttacac tatcaactgc ttcagcactt aatttgaatg
    15421 ctaacatcca tgagtctgga cgtgatggtg tgttgcaaat ttctggttac agatatgttg
    15481 attacttgga gcttgatgat agaactgttt ctccagttga gcaacccaaa gttgtgaccg
    15541 acaaaggcga accagaagtt cagccagcgt taccagaagc tgttgtaact ggaaaaggga
    15601 aaactgaagt acaaccgaca ttaccagaag ctgttgtgac tgaaaaaggg gaaccggaag
    15661 tacaaccagt gttaccagaa gctgttgtgg ctgaaaaagg ggaaccggaa gtacaaccag
    15721 tgttaccaga agctgttgtg gctgaaaaag gggaaccaga agtacaacca gccttacccg
    15781 aagcagttgt aactgaaaaa ggcgaaccag aagttcatga gaagcctgac tatacgcaac
    15841 caataggtgc aaaccttgtt gagcctgaag ttcatgagaa actagcatac actgaacctg
    15901 taggtacaac aggagtagat gaaaatggaa acttgattga gccacctgtt aacgatattc
    15961 cagagtatac tgaaccaata tctacagttt cagaagttgc atcagaaaga gaagagttgc
    16021 cttctttaca taccgatatt cgtacagaga ctattcctaa aaccactata gaagaatctg
    16081 atcctagcaa atttataggc gataattctg ttaaacaagt tggtgaggat ggcgaacgtc
    16141 aaattgttac tagctatgaa gagttacatg gcaaaaaaat cagcgagtca gttgaaacag
    16201 taacaatttt gaaagaaatg aagcctgaaa ttattgtaaa aggtacaaaa gaaagaccaa
    16261 aagaaaaaac ggctcctgtt ttaaccttga ccaaagtaac agaagatgct atgaatcgtt
    16321 ctgccaactt aaattatgag cttgataata aagataatgc tgaaatatca agtattgtag
    16381 ctgaaattaa agatggtgat acagtagtta aaagggttga tttatctaaa gaaaaattaa
    16441 ctgacgctgt acaaaatttg gatttgttta aagattataa gattgcaaca acaatgattt
    16501 atgatcgtgg tcaaggttct gaaacgtcta aactggatga aagacctctg cgtttggagt
    16561 tgaaaaaggt cgaaattaaa aatatcgcat ctactaattt agtgaaggta aatgatgatg
    16621 gtactgaaac acctagtgat tttatgaatg aaaaaccttc agaagaagat gttaaaaaaa
    16681 tgtacttaaa aatcactagt cgcgataata aggtaactcg tttaactgta gactctattg
    16741 aagaagtgac tgaagaaggt caaaaacttt acaaaataac tgctgaagca caagatttga
    16801 ttcaacacac agacccaacg aaggttcgta ataagtatgt ttattatata gaaaaacccc
    16861 atcctaaaga agataatgtc tactataact ttaaagattt agtagatgct atgaatactg
    16921 ataaaaatgg tacatttaaa cttggtgcag atttgaatgc cactggtgtt ccaacaccta
    16981 agaaatggta tgttgacggc gactttagag gtacattgaa gagtgtagag gggaaacatt
    17041 atactatcca caacacggag cgtccgttat tccagaatat tattggtggt acagtaacca
    17101 aagtaaatct gggaaatgta aatatcaata tgccatgggc agaccgcatc gcaccgattg
    17161 ctgacactat taaaggtggc gctaaaattg aagatgtcaa agtgactggt aacgtattag
    17221 gtagaaactg ggtatctgga tttattgata agattgacaa ccaaggtaca ctcagaaatg
    17281 tagcctttat cggaaatgtg acatctgtag gtgatggtgg tcaattcttg accggtatcg
    17341 ttggtgagaa ctggaaagga ctagtcgaac gtgcgtatgt tgacgcaaat cttattggca
    17401 agaaagccaa ggctgctggt attgcttatt ggacacaaaa cagtggtgac aatcataaag
    17461 ttggtgtcga aggtgcagtc aagaaaggaa ttgtgaaggg taccattcag gtagaaagtc
    17521 ctgttgaagt cggcggtgct gttggacgtt tgagtcatca tggttatatc ggggaagtcg
    17581 tatctatgat gaaagttaag aagggtgaaa ttttttatgg ttctagtgat atgaatgatg
    17641 acccatattg ggtggcgaat aatgtacgag gaaattatgt agttaatggt gtgagtgaag
    17701 gtacgatatc ttatgctcgt gctaaagaac accatcgtat caaaccaatt tcacagtcag
    17761 aagcagatac taaaattatg atgttaggta ttacagcaca agattttgct atcaacgaac
    17821 ctgtggtcaa tcgcttaaac cgtttaacca gaaaagaaga tgaatataag tcaacccaag
    17881 actataaagt agatcgagat ctggcttatc gtaatattga gaaacttcaa ccattttata
    17941 acaaagaatg gattgtcaac caaggtaaca aacttgcaga agattcaaac ttagctaaga
    18001 aagaagtcct ttctgttacg ggtatgaagg atggacagtt tgtaactgac ttatcagata
    18061 ttgataagat tatggttcac tatgctgatg gtactaaaga agaaatggac gtcactaaga
    18121 atgctgattc taaagtgaaa caagttcgtg aatataccat cgctggacaa aacgttgttt
    18181 atacaccaaa tatggttgag aaagaccgta accaattgat tcaagatatc aaagataagt
    18241 tggcgtcagt tcaattgatt tctcctgaag tacgtgcttt gatggatgca cgtaagaaac
    18301 cagaagaaaa tactgatgaa cgtaagaatg gttatattaa agacctttac ttagaagaaa
    18361 gctttgctga aacgaaagct aatcttgata aattggttaa atccttagtt gaaaatgcag
    18421 atcatcaatt aaatagtgac gaagcggcta tgaaagcact tgttaagaag gtggatgaaa
    18481 ataaagctaa aatcatgatg gctctgactt atctcaatcg ttactatgat atcaagtatg
    18541 gggatatgac tatcaagaac ttgatgatgt ttaaacctga tttctatggt aaatcagttg
    18601 accttcttga tttcttgatt cgaattggat caagtgagag aaatatcaaa ggtgacagaa
    18661 ctttggatgc ttatcgtgat atgattggtg gaactattgg taagtctgaa ttacatggat
    18721 tcttagatta caatatgcgt ctcttcacta acgatactga tttaaatgat tggttcatcc
    18781 atgcagctaa gaatgtatat gtatcagaac ctcaaacaac gaacccagat tttgttaata
    18841 aacgacatcg tgcatttgat ggtttgaaca acggtgttca taatcgtatg attctacctc
    18901 tattaactct taagaatgca catatgttct tgatttcaac ttacaataca atggcttata
    18961 gttcttttga gaaatatggt aagtatacag aagaagctag aaatgaattc aaaaaagaaa
    19021 ttgataaggt tgcacatgct caacaaacat acttagactt ctggtcacgt ttagcattgc
    19081 caagcgtacg tgaccaatta ctcaagagtg agaatagggt accaactcct gtgtgggata
    19141 accaaaacta tagtggtatt aaaggaataa accgtatggg ttatgatgag aagaaagtac
    19201 caattgcgcc aattcgtgag ttatatggtc caacttggaa attccataat accaactgga
    19261 atatgggagc tatggcatct attttcccaa atcctaataa caatgaccaa gtttatttca
    19321 tgggaacaaa tatgattagt ccgtttggta tttcagcctt tactcatgaa actacacacg
    19381 ttaatgatag aatgctttac ttcggtggtc atagacaccg tcaaggtaca gacgtcgaag
    19441 cctatgctca aggtatgcta caaactccgt caagtattgg tcaccaaggt gaatatggtg
    19501 ctttaggttt gaacatggct tatcatcgtg aaaatgatgg tgaccaatgg tataactatg
    19561 accctgataa gcttcaaact cgtgaagata tcgatcgata tatgaaaaac tataatgaag
    19621 cactgatgat gctagatcat gtagaagcag acgccgtact tccacaattg aatggtgata
    19681 atagcaagtg gttcaagaaa attgatagag aaatgcgcag aaatcttggg gatggtttga
    19741 ataacttagt agcaccgcac caatgggaca acgttcgtga cttaaatcaa gaagagagtt
    19801 ctaagaaatt atcaagtatt aacgatttga ttgataataa tttcatgacc aaacacggaa
    19861 atccaggtaa cggacgttat agaccagagg attttagacc aaactcagct tacgtaaatg
    19921 tcaatatgat ggcaggaatt tacggtggga atacgagtca aggtgctcct ggttcattat
    19981 cgttcaaaca taatgccttc cgtatgtggg gttattatgg atatgacaaa ggtttcacta
    20041 gttatgtatc tagcaaatat caaggtgaag ctgataaaca aaaccagggt agattaggtg
    20101 atgatttcat tatcaaaaaa gtttcaaaca accaattctc aaatcttgaa gattggaaga
    20161 aatattggta tcatgatgtg aaatccagag ctgaaaaagg attcacagag attacaattg
    20221 atggacaaac cattcacaac tataatgaac tgaaagactt attcgacaaa gctgtcacag
    20281 aagacctcaa gaaagctgga aactactcaa atactgagaa tttgaaatcc aaagtcttca
    20341 aagctcttct taaaaacaca gacggtttct ttaatccatt gttcaaaaaa gacattt
//
LOCUS       DBERAE010000040        20396 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.40, whole genome shotgun sequence.
ACCESSION   DBERAE010000040 DBERAE010000000
VERSION     DBERAE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.40"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            113..547
                     /locus_tag="ACL70N_001661"
     CDS             113..547
                     /locus_tag="ACL70N_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0590425.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAARGGVVNGKELFSTDAEEEEEDFESGI"
     gene            559..1749
                     /locus_tag="ACL70N_001662"
     CDS             559..1749
                     /locus_tag="ACL70N_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGS0590426.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1760..2251
                     /locus_tag="ACL70N_001663"
     CDS             1760..2251
                     /locus_tag="ACL70N_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590427.1"
                     /translation="MTMPNIVMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2266..3045
                     /locus_tag="ACL70N_001664"
     CDS             2266..3045
                     /locus_tag="ACL70N_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0590428.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFVFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3032..3850
                     /locus_tag="ACL70N_001665"
     CDS             3032..3850
                     /locus_tag="ACL70N_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0590429.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEVFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3850..4143
                     /gene="yajC"
                     /locus_tag="ACL70N_001666"
     CDS             3850..4143
                     /gene="yajC"
                     /locus_tag="ACL70N_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS0590430.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4165..6066
                     /locus_tag="ACL70N_001667"
     CDS             4165..6066
                     /locus_tag="ACL70N_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGS0590431.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6126..7127
                     /locus_tag="ACL70N_001668"
     CDS             6126..7127
                     /locus_tag="ACL70N_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0590432.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKKLNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7237..7572)
                     /locus_tag="ACL70N_001669"
     CDS             complement(7237..7572)
                     /locus_tag="ACL70N_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590433.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7583..7825)
                     /locus_tag="ACL70N_001670"
     CDS             complement(7583..7825)
                     /locus_tag="ACL70N_001670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590434.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7841..8035)
                     /locus_tag="ACL70N_001671"
     CDS             complement(7841..8035)
                     /locus_tag="ACL70N_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0590435.1"
                     /translation="MNRVKEFRKELGISQLELAKNIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8201..9151
                     /gene="rsmH"
                     /locus_tag="ACL70N_001672"
     CDS             8201..9151
                     /gene="rsmH"
                     /locus_tag="ACL70N_001672"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGS0590436.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DRKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9163..9480
                     /gene="ftsL"
                     /locus_tag="ACL70N_001673"
     CDS             9163..9480
                     /gene="ftsL"
                     /locus_tag="ACL70N_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGS0590437.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9484..11736
                     /gene="pbp2X"
                     /locus_tag="ACL70N_001674"
                     /gene_synonym="pbpX"
     CDS             9484..11736
                     /gene="pbp2X"
                     /locus_tag="ACL70N_001674"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGS0590438.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11738..12718
                     /gene="mraY"
                     /locus_tag="ACL70N_001675"
     CDS             11738..12718
                     /gene="mraY"
                     /locus_tag="ACL70N_001675"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGS0590439.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13281..15386
                     /locus_tag="ACL70N_001676"
     CDS             13281..15386
                     /locus_tag="ACL70N_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0590440.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(15682..16164)
                     /locus_tag="ACL70N_001677"
     CDS             complement(15682..16164)
                     /locus_tag="ACL70N_001677"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGS0590441.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16259..17743)
                     /locus_tag="ACL70N_001678"
     CDS             complement(16259..17743)
                     /locus_tag="ACL70N_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGS0590442.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMSERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            17896..19503
                     /locus_tag="ACL70N_001679"
     CDS             17896..19503
                     /locus_tag="ACL70N_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGS0590443.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            19668..19835
                     /locus_tag="ACL70N_001680"
     CDS             19668..19835
                     /locus_tag="ACL70N_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGS0590444.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(19828..20396)
                     /locus_tag="ACL70N_001681"
                     /pseudo
     CDS             complement(19828..20396)
                     /locus_tag="ACL70N_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         6156 a         3679 c         4615 g         5946 t
ORIGIN      
        1 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
       61 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
      121 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
      181 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
      241 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
      301 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
      361 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
      421 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccggg gcggagtcgt
      481 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
      541 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
      601 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
      661 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
      721 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
      781 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
      841 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
      901 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
      961 agagaagcaa ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
     1021 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
     1081 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
     1141 gatattgcag aaagtcattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
     1201 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
     1261 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
     1321 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
     1381 aattatttct tgaatcgtct gccaaaagat catgtgtcct attgggattt gatttttaat
     1441 gatggtagtg ctcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
     1501 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
     1561 catgccatgc ttcgttcctt gatcgaacat tatgcaaatg atcaatttac ccctggtggg
     1621 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
     1681 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
     1741 tattggtagg aggagaaata tgacaatgcc aaatattgtt atgacccgta tcgatgaacg
     1801 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
     1861 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
     1921 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
     1981 taatcctgct caaacgatct ttatcgttgt aaagaatgtg aaggatgctt taaccttggt
     2041 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg ctactggtaa
     2101 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggtggccc tcaaggaatt
     2161 gagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
     2221 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
     2281 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
     2341 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
     2401 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
     2461 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
     2521 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
     2581 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
     2641 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
     2701 atttggttgt ttgtctttat tggatttacc ttgggttgct tgggcgccct ttcaatggat
     2761 accttgttga aactcgtaga ctacattcca ccggtattgc ttacaggttt gacagttgct
     2821 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
     2881 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
     2941 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
     3001 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
     3061 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
     3121 ctatcaaggg ttgggatatg ccaatgtgat gtatcctgct ttgaaaaaac actatggaga
     3181 ggatcaggaa gttttctacc aagccttgga agaaaactgt gaattctata ataccaaccc
     3241 acacttcctg ccttttatta ccagcttgca tcttgtaatg ttggaaaatg gccgaccaac
     3301 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
     3361 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
     3421 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
     3481 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
     3541 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
     3601 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
     3661 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
     3721 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
     3781 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
     3841 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
     3901 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
     3961 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
     4021 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
     4081 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
     4141 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagaatc
     4201 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
     4261 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
     4321 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
     4381 gatccagaat gggcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
     4441 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
     4501 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
     4561 attcgttcct ttacttggtt gaaactactc ttgcttctct tgaaatttga cttgctagag
     4621 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
     4681 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
     4741 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
     4801 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
     4861 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
     4921 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
     4981 acaggcttag atggacgaac tttggctttt ggtgatagcg attctacaga aacgacagaa
     5041 attttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
     5101 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
     5161 tttgaaaaga gagcttggca gcctaggtcc atgatctttg aagactctgg acatgtctgc
     5221 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
     5281 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
     5341 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
     5401 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
     5461 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgaa
     5521 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
     5581 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
     5641 ttgactcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
     5701 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
     5761 gagcttgaaa gaagtagcaa actcaccaag cgccaattct ttgagaatca gatgctggat
     5821 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
     5881 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
     5941 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
     6001 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
     6061 tgctagaaat aggcattttg aatagtgaac atgttataat aagtattagt aggaggtgtt
     6121 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
     6181 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
     6241 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
     6301 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
     6361 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
     6421 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
     6481 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
     6541 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
     6601 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
     6661 gttatgaaca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
     6721 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
     6781 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
     6841 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
     6901 ttatcaaaaa gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
     6961 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
     7021 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
     7081 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
     7141 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
     7201 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
     7261 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
     7321 taggaatatt gaaaatttcc attggacagg gttggttaaa agttgtggaa aggatatgag
     7381 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
     7441 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
     7501 tgaaataagg gcaaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
     7561 tagtgatttc ataaggtacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
     7621 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
     7681 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
     7741 gtggaattat aaaaaatatc actgttccat aaatcgaacc tgctttcaga ccaggataac
     7801 gtaactgttt cttttctttt ttcatgagtt tgctcctttt ttaaaaatct tcctcccaaa
     7861 agagactgtt gaggtcagtt tggaggctgc gggcgagatt gagacagagt tccaaggttg
     7921 gattgtactt gtcgttttca atcatattga tagtctgtct cgagacaccg atattcttgg
     7981 cgagctcgag ctgggaaatg cccagttcct tgcgaaattc tttcacacga ttcatctgtt
     8041 cttctttctg atttatgtcg tatatatttg actatattat agtcttttaa acataaagtg
     8101 tcaagtattt ttgacatatt ttttgaagaa atagtagtct ccttgtccta tttgtctgac
     8161 aagtgcaagc tggtcggatt tgtggtaaaa tagataagat atgacaaaag aatttcatca
     8221 tgtaacggtc ttactccacg aaacgattga tatgcttgac gtaaaacctg acggtatcta
     8281 cgttgatgcg actttgggtg gagcaggcca tagcgagtat ttattaagta aattaagtga
     8341 aaaaggccat ctctatgcct ttgaccagga tcagaatgcc attgacaatg cgcaaaaacg
     8401 cttggcacct tacattgaga agggaatggt gacctttatc aaggataact tccgtcattt
     8461 acaggcacgt ttgcgcgaag ctggtgttca ggaaattgat ggaatttgtt atgacttggg
     8521 agtgtctagt cctcaattag accagcgtga gcgtggtttt tcttataaaa aggatgcgcc
     8581 actggacatg cggatgaatc aggatgctag tctgacagcg tatgaagtgg tgaacaatta
     8641 tgactatcat gacttggttc gtattttctt caagtatgga gaggacaaat tctctaaaca
     8701 gattgcgcgt aagattgagc aagcgcgtga agtgaagccg attgagacaa cgactgagtt
     8761 agcagagatt atcaagttgg tcaaacctgc caaggaactc aagaagaagg gtcatcctgc
     8821 taagcagatt ttccaggcta ttcgaattga agtcaatgat gaactggggg cggcagatga
     8881 gtccatccag caggctatgg atatgttggc tctggatggt agaatttcag tgattacctt
     8941 tcattcctta gaagaccgct tgactaagca attgttcaag gaagcttcaa cagttgaagt
     9001 tccaaaaggc ttgcctttca tcccagatga tcgcaagccc aagatggaat tggtgtcccg
     9061 taagccaatc ttgccaagtg cggaagagtt agaagccaat aaccgctcgc actcagccaa
     9121 gttgcgcgtg gtcagaaaaa ttcacaagta agagggaaaa agatggcaga aaaaatggaa
     9181 aaaacaggtc aaatactaca gatgcaactt aaacggtttt cgcgtgtgga aaaagctttt
     9241 tacttttcca ttgctgtaac cactcttatt gtagccatta gtattatttt tatgcagacc
     9301 aagctcttgc aagtgcagaa tgatttgaca aaaatcaatg cgcagataga ggaaaagaag
     9361 accgaattgg acgatgccaa gcaagaggtc aatgaactat tacgtgcaga acgtttgaaa
     9421 gaaattgcca attcacacga tttgcaatta aacaatgaaa atattagaat agcggagtaa
     9481 gatatgaagt ggacaaaaag agtaatccgt tatgcgacca aaaatcggaa atcgccggct
     9541 gaaaacagac gcagagttgg aaaaagtctg agtttattat ctgtctttgt ttttgccatt
     9601 tttttagtca attttgcggt cattattggg acaggcactc gctttggaac agatttagcg
     9661 aaggaagcta agaaggttca tcaaaccacc cgtacagttc ctgccaaacg tgggactatt
     9721 tatgaccgaa atggagtccc gattgctgag gatgcaacct cctataatgt ctatgcggtc
     9781 attgatgaga actataagtc agcaacgggt aagattcttt acgtagaaaa aacacaattt
     9841 aacaaggttg cagaggtctt tcataagtat ctggacatgg aagaatccta tgtaagagag
     9901 caactctcgc aacctaatct caagcaagtt tcctttggag caaagggaaa tgggattacc
     9961 tatgccaata tgatgtctat caaaaaagaa ttggaagctg cagaggtcaa ggggattgat
    10021 tttacaacca gtcccaatcg tagttaccca aacggacaat ttgcttctag ttttatcggc
    10081 ctagctcagc tccatgaaaa tgaagatgga agcaagagct tgctgggaac ctctggaatg
    10141 gagagttcct tgaacagtat tcttgcaggg acagacggca ttattaccta tgaaaaggat
    10201 cgtctgggta atattgtacc cggaacagaa caagtttccc aacgaacgat ggacggtaag
    10261 gatgtttata caaccatttc cagccccctc cagtccttta tggaaaccca gatggatgct
    10321 tttcaagaga aggtaaaagg aaagtacatg acagcgactt tggtcagtgc taaaacaggg
    10381 gaaattctgg caacaacgca acgaccgacc tttgatgcag atacaaaaga aggcattaca
    10441 gaggactttg tttggcgtga tatcctttac caaagtaact atgagccagg ttccactatg
    10501 aaagtgatga tgttggctgc tgctattgat aataatacct ttccaggagg agaagtcttt
    10561 aatagtagtg agttaaaaat tgcagatgcc acgattcgag attgggacgt taatgaagga
    10621 ttgactggtg gcagaatgat gactttttct caaggttttg cacactcaag taacgttggg
    10681 atgaccctcc ttgagcaaaa gatgggagat gctacctggc ttgattatct taatcgtttt
    10741 aaatttggtg ttccgacccg tttcggtttg acggatgagt atgctggtca gcttcctgcg
    10801 gataatattg tcaacattgc gcaaagctca tttggacaag ggatttcagt gacccagacg
    10861 caaatgattc gtgcctttac agctattgct aatgacggtg tcatgctgga gcctaaattt
    10921 attagtgcca tttatgatcc aaatgatcaa actgctcgga aatctcaaaa agaaattgtg
    10981 ggaaatcctg tttctaaaga tgcagctagt ctaactcgga ctaacatggt tttggtaggg
    11041 acggatccgg tttatggaac catgtataac cacagcacag gcaagccaac tgtaactgtt
    11101 cctgggcaaa atgtagccct caagtctggt acggctcaga ttgctgacga gaaaaatggt
    11161 ggttatctag tcgggttaac cgactatatt ttctcggctg tatcgatgag tccggctgaa
    11221 aatcctgatt ttatcttgta tgtgacggtc caacaacctg aacattattc aggtattcag
    11281 ttgggagaat ttgccaatcc tatcttggag cgggcttcag ctatgaaaga ctctctcaat
    11341 cttcaaacaa cagctaaggc tttggagcaa gtaagtcaac aaagtcctta tcctatgccc
    11401 agtgtcaagg atatttcacc tggtgattta gcagaagaat tgcgtcgcaa tcttgtacaa
    11461 cccatcgttg tgggaacagg aacgaagatt aaaaacagtt ctgctgaaga agggaagaat
    11521 cttgccccga accagcaagt ccttatctta tctgataaag cagaggaggt tccagatatg
    11581 tatggttgga caaaggagac tgctgagacc cttgctaagt ggctcaatat agaacttgaa
    11641 tttcaaggct cgggctctac tgtgcagaag caagatgttc gtgctaacac agctatcaag
    11701 gacattaaaa aaattacatt aactttagga gactaatatg tttatttcca tcagtgctgg
    11761 aattgtgaca tttttactaa ctttagtagg aattccggcc tttatccaat tttatagaaa
    11821 ggcgcaaatt acaggccagc agatgcatga ggatgtcaaa cagcatcagg caaaagctgg
    11881 gactcctaca atgggaggtt tggttttctt gattacttct gttttggttg ctttcttttt
    11941 cgccctattt agtagccaat tcagcaataa tgtgggaatg attttgttca tcttggtctt
    12001 gtatggcttg gtcggatttt tagatgactt tctcaaggtc tttcgtaaaa tcaatgaggg
    12061 gcttaatcct aagcaaaaat tagctcttca gcttctaggt ggagttatct tctatctttt
    12121 ctatgagcgc ggtggcgata tcctgtctgt ctttggttat ccagttcatt tgggattttt
    12181 ctatattttc ttcgctcttt tctggctagt cggtttttca aacgcagtaa acttgacaga
    12241 cggtgttgac ggtttagcta gtatttccgt tgtgattagt ttgtttgcct atggagttat
    12301 tgcctatgtg caaggtcaga tggatattct tctagtgatt cttgccatga ttggtggttt
    12361 gctcggtttc ttcatcttta accataagcc tgccaaggtc tttatgggtg atgtgggaag
    12421 tttggcccta ggtgggatgc tggcagctat ctctatggct ctccaccagg aatggactct
    12481 cttgattatc ggaattgtgt atgtttttga aacaacttct gttatgatgc aagtcagtta
    12541 tttcaaactg acaggtggta aacgtatttt ccgtatgacg cctgtacatc accattttga
    12601 gcttggggga ttgtctggta aaggaaatcc ttggagcgag tggaaggttg acttcttctt
    12661 ttggggagtt gggcttctag caagtctcct gaccctcgca attttgtatt tgatgtaaga
    12721 atggcaccct gatgtttcag ggtgtttttg tgtttaaata cacaatgaaa atcaaagaac
    12781 aaactagaaa gctaacttta ggctgctcaa aatataatat attgaaacta gaatagtaca
    12841 cctctacttc taaaacattg ttagaaatcg atttgactgt cctgaacgat ttatcctgtt
    12901 cttatttcat tttactatac agtttcgagg ttgtagataa ggcgaagctg atgtggtttg
    12961 aagagatttt cgaagagata aaaaatattg gtcaattaaa gtcaaaatcc ttgacctttt
    13021 ctgactaatg tagtatatta tgaacgtaag gtaaatgaaa gccttactag aacacttatt
    13081 taaagtaaaa tagaaagagg tggggtctat gtttaatcta gaaatcttca gaagtaaaga
    13141 tggtctactc ctgcttgaaa aagaaaaacc agaaatagta cgtagggtag cggtttagct
    13201 agtctaaatt ttttaaaaca aaggtcaaag atagtcaata tcagtaatca taactaagta
    13261 aacaaaaaga ggtaaagaat atgaataaca actttaataa ttttaataac atggatgatt
    13321 tatttaacca attgatgggt ggtatgcgag gatacagttc tgaaaatcgc cgttacttaa
    13381 ttaatgggcg cgaagtcaca cctgaggaat ttgctcacta tcgtacgact ggtcaattac
    13441 caggaaatgc agaaactgat gtgcaaatgt cacaacaggc atcaggtatg aaacaagacg
    13501 gtgtccttgc aaaactaggt cgaaacttga cagcagaagc gcgtgagggt aagttggatc
    13561 ctgttatcgg acgaaacaag gaaattcaag aaacatctga aatcctctca cgccgcacca
    13621 agaacaatcc tgttttggtc ggagatgcag gtgttggtaa gacagcagtt gtcgaaggtc
    13681 tagcgcaagc cattgtgaac ggagatgttc ctgctgctat caagaacaag gaaattattt
    13741 ctattgatat ctcaggtctt gaggctggta ctcaataccg tggtagcttt gaagaaaatg
    13801 tccaaaactt agtcaatgaa gtgaaagaag cagggaatat tatcctcttc tttgatgaaa
    13861 ttcaccaaat tcttggtgct ggtagcactg gtggagacag tggttctaaa ggacttgcgg
    13921 atattctcaa gccagctctc tctcgtggag aattgacagt gattggggca acaactcaag
    13981 acgaataccg taacaccatc ttgaagaatg ctgctcttgc tcgtcgtttc aacgaagtga
    14041 aggtcaatgc tccttcagca gagaatactt ttaacattct tcaaggcatt cgtgacctct
    14101 atcaacaaca tcacaatgtc atcttgccag acgaagtctt gaaagcagcg gtggattatt
    14161 ctgttcaata cattcctcaa cgtagcttgc cagataaggc tattgacctt gtcgatgtaa
    14221 cagctgctca cttggcggct caacatccag taacagatgt gcatgctgtt gaacgagaaa
    14281 tcgaaacgga aaaagacaag caagaaaaag cagttgaagc agaagatttt gaagcagctc
    14341 taaactataa aacacgcatt gcagaattgg aaaagaaaat cgaaaaccac acagaagata
    14401 tgaaagtgac tgcaagtgtc aacgatgtgg ctgaatctgt ggaacgaatg acaggtatcc
    14461 cagtatcgca aatgggagct tcagatatcg aacgtttgaa agatatggct catcgcttgc
    14521 aagacaaggt gattggtcaa gataaggccg tagaagttgt agctcgtgct atccgtcgta
    14581 accgtgctgg ttttgatgaa ggaaatcgcc caatcggcaa cttcctcttt gtagggtcta
    14641 ctggggttgg taagacggag cttgctaagc aattggcact cgatatgttt ggaacccagg
    14701 atgcgattat ccgtttggat atgtctgaat acagtgaccg cacagctgtt tctaagctaa
    14761 ttggtacaac agcaggctat gtgggttatg atgacaatag caatacctta acagaacgtg
    14821 ttcgtcgcaa tccatactct atcattctct tggatgaaat tgaaaaggct gaccctcaag
    14881 ttattaccct tctcctccaa gttctagatg atggtcgttt gacagatggt caaggaaata
    14941 cagtaaactt caagaacact gtcattattg cgacctcaaa tgctggattt ggctatgaag
    15001 ccaacttgac agaagatgcg gataaaccag aattgatgga ccgtttgaaa cccttcttcc
    15061 gtccagaatt cctcaaccgc tttaatgcag tcatcgagtt ctcacacttg actaaggaag
    15121 acctttctaa gattgtagat ttgatgttgg ctgaagttaa ccaaaccttg gctaagaaag
    15181 acattgactt ggtagtcagt caagcggcta aagattatat cacagaagaa ggttacgacg
    15241 aagtcatggg ggttcgtcct ctccgtcgag tggttgaaca agaaattcgt gataaggtga
    15301 cagacttcca cttagatcat ttagatgcta aacatctgga agcagatatg gaagatggcg
    15361 ttttggttat tcgtgagaaa gcctaagata gaattttgag gataaaaaag aaggagccag
    15421 ctgaaaaaaa ctggttcctt ttgaggtacg acgggcatgt cgtacagtag aagtgtacta
    15481 ttctagtttc aatccactat agtagctcag aagtcggtac ttaaacgtgc tatatcaaaa
    15541 ccagtccttg aaaaacgtgg attggtttcg tgtttggatt attaccttga acgacatgcg
    15601 ttaaaagtta gttgaaccgc cgtatgccga acggcacgta cggtggtgtg agaggggcta
    15661 gagattatcc cctactcgat tttaaatcac atgacgttca aaggcatcat ctgaaatccc
    15721 ttgttccaag atgagttttg cccattcttt agcagagaag aggctgtggt ccttgtagtt
    15781 tccgcaagat tcgatggttg tccctgggac atcttcccaa gtagtagttt cagcgatttc
    15841 cttgagcgaa tccttgataa cagctgcgat tttagcactg gtgtgacgtc cccacataat
    15901 catgtggaag cctgtgcggc aaccaaatgg tgaacagtca atcatgccgt caatgcgggt
    15961 acggatgagt ttggctaaga ggtgctcgat agtgtgaagg ccggcagtag ggatagagtc
    16021 ttcgtttggt tgcaccaagc gaatatcata attggagatg atgtctcctt ttggtcctgt
    16081 ttcttcccca atcaagcgaa catagggtgc tttgacaatg gtgtggtcaa gttcaaaact
    16141 ttcgacaata acttcttttg acatggtaaa tcctttcagt tttcttctct cattatatca
    16201 taaaggttgt tcctgagaca gagagaaaac ctctccgagg ctagagaggt tgaaatcttt
    16261 acttacgata taagcggtcg tattggtagt atgggtcaaa ggttacgttg atacccagtt
    16321 tacgaaggac attcttgtct tcatcagtca agatgatggt tgagtgggct tcgcttcctt
    16381 tgaggttgcc tagttcttcc atagcgcggg cagcatcagg attttctgta gctgtgatag
    16441 caagtgcaat caggatttca tttgaatgaa ggcgtggatt gcggctaccg agatgatcga
    16501 ttttaagacc ttggattggc ttaacaactt caggttcgat tagttttact tctttagcga
    16561 tgtcagctga ttttttgatg gcgttgatca aggcagcggc tgtaggacca aagagttctg
    16621 agttcttacc agtgacgatt tccccatttg gcaattcaaa ggctagggct ggtccaccag
    16681 tttcttctgc tttttggcgc gcaacgacag caaccttacg gtctgcaggt gtgataccga
    16741 ggtcgttcat gagcaactca attttcttga cggcagcttc gccaactttt tcagctttga
    16801 agtcaagaac tgtttgatag taacggcgga tgatttcttg tttagaagct tcgacagcgg
    16861 cctcgtcatc tgtaatagcg aaaccaacca tgttgacacc catatctgtc ggtgaagcgt
    16921 atggtgattt tccgagaata cgttccgaca tgcgtttgag cactgggaag atttcgatat
    16981 cacggttgta gttgacagtg gtttctccat aggtttgaag atggaagggg tcaatcatgt
    17041 tgacatcatc aaggtcagct gtggcagctt cataagccaa gttaactgga tgatgaaggg
    17101 gaagattcca aacagggaag gtttcaaatt tagcgtagcc agatttgatg ccattgattt
    17161 ggtcgtggta catattggac atacacgttg ccaattttcc agaaccgggt ccaggagcgg
    17221 ttacgacaat caagttgcga ctggttttga tgtagtcgtt tttgcccatg cctcctgggg
    17281 aaatgatgtg atccatatcc gtaggatatc ctttgattgg ataatgaaga taagaatcaa
    17341 ttccgttttt ctcaagttgg ttgcggaagg catctgcagc gggttggcca gcgtattgtg
    17401 taatgacaac ggaaccaaca aaaatcccta attcattgaa tttgtcaatc aaacgaagaa
    17461 cttcttggtc ataagaaatg cctaagtcgc cacgtgcttt ggaatgttca atgttgctag
    17521 cattaatggc aatcacaacc tcaacctgct ctttcaattc ttgcaagagc ttgattttgt
    17581 tgtcaggttc ataaccagga aggacacgag cagcgtggaa atcttctaac attttaccgc
    17641 caaactctaa gtagagcttg ccgtcaaatt ggttaatgcg ctccaaaata tggtcgcgtt
    17701 gtaaattcaa atactgttca gaactaaaag cttgtttttt cattttttta cctctggact
    17761 ctattataat aaaaaattgg aagttaggaa actacggagc taaaaaagaa attaaaaaga
    17821 ttaagcaaac gcttgcacaa aattttaaaa agtgctatca tagactatag attattaaaa
    17881 taatgaggta aacagatgca agaaaaatgg tggcataatg ccgtagtcta tcaagtctat
    17941 ccaaagagtt ttatggatag taatggagat ggagttggtg atttgccagg tattaccagt
    18001 aagttggact atctagctaa gttaggaatc acagcgattt ggctttctcc cgtttatgac
    18061 agccctatgg atgataatgg ctacgatatt gctgattatc aagcgattgc ggctattttt
    18121 ggaaccatgg aggacatgga tcagctgatt gcagaagcta agaagcgtga tatccgtatc
    18181 atcatggact tggtggtcaa tcatacctcg gatgagcatg cttggtttgt cgaagcctgt
    18241 gaaaatactg acagccctga gcgagactac tatatctggc gcgatgaacc caatgaccta
    18301 gattctatct ttagtgggtc tgcttgggaa tacgatgaaa agtcaggtca atactatctc
    18361 cactttttca gcaagaaaca gccggatctc aactgggaaa atgaaaaact tcgccagaaa
    18421 atttatgaga tgatgaactt ctggattgat aaaggtattg gtggtttccg tatggatgtt
    18481 attgacatga ttggcaaaat tcctgacgag aaggtagtca ataatggtcc tatgctccat
    18541 ccctatctca aggaaatgaa tcaggcgacc tttggagata aggagctctt gacagtaggg
    18601 gagacttggg gagcaacgcc agagattgcc aagctctact ctgatccaaa ggggcaagaa
    18661 ttgtctatgg tcttccagtt tgaacatatc ggtcttcagt atcaggaagg tcagcctaaa
    18721 tggcactatc aaaaagagct gaatatcgct aagttaaaag aaatcttcaa caaatggcag
    18781 acagagttag gagttgagga cggctggaat tccctcttct ggaacaacca tgacctccct
    18841 cgtattgtct caatctgggg aaatgaccaa gaataccgcg aaaaatctgc caaagccttt
    18901 gcaatcttac ttcatctcat gagaggaact ccttatatct accaaggtga ggagattggg
    18961 atgaccaact atccgtttga aacactggat caagtagaag atattgaatc cctcaactat
    19021 gcgcgtgagg ctcttgaaaa aggtgttccg attgaagaaa tcatggacag tatccgtgtt
    19081 attggacgtg acaatgcccg tacccctatg caatgggacg agagcaaaaa cgctggtttc
    19141 tcaacaggtc aaccttggtt ggcggttaat ccaaattacg agatgatcaa cgtccaagaa
    19201 gcgctggcaa atccagattc tattttctat acctatcaga aactggtcca aattcgcaag
    19261 gagaatagct ggctaattcg agctgacttt gaattgcttg atacggctga taaggtcttt
    19321 gcttatatac gtaaggatgg cgaccgtcgc ttcctagttg tggctaactt gtctaatgaa
    19381 gagcaagact tgacagtaga aggaaaagtc aaatctgtct tgattgaaaa caccctagct
    19441 caagaagtct ttgaaaaaca aatcttagtt ccatgggatg ctttctgtgt ggaattacta
    19501 taaatatttt ttgcagaaaa atttaaaatt gaaatcgtat aaaaacaagg gaggactgta
    19561 taaaaggcag aaatcctttg ttttttataa ccaaggttta taaaccttca ttctcgaaat
    19621 tcaattaact ttacaaattc ccactattaa ggagaaagaa gacgaacata aagaagcgta
    19681 tccttagtgc aggcctgact tttacatctg atttgctttt agctgcttgc ggccaatcag
    19741 gttcagatac aaaaacttac tcatcaacct ttagtggaaa tccaactaca tttaactatc
    19801 tattagacta ttacgctgat aatatagtca attgaaacaa gaacaggaca aaagagcctc
    19861 ataaaaggta ttgcaacttg gtaatacctt tttgaggtgc tttttgatat gagcccatgt
    19921 tttctcaata ggattgtact caggcgagta gggaggaaga ggtaaaagtt tatgcccaaa
    19981 ctcttcacac aagagttcta gcttccccat tctatggaat cttgcattat ccataataat
    20041 aaccgatggt gtggttaatg ttggtaagag aaacttctga aaccaagctt caaaaaagtc
    20101 gctcgtcatc atctcttcgt aagtcattgg agcgattaac tcaccattca tttgttagac
    20161 ctgcaaccaa agaaatcctc tgatatcttc ttccagatac tttacctctt cttaactgac
    20221 cttttaatga gcgaccatat tctcgatgaa aataagtatc gaatcctgtt tcatcaatct
    20281 aaacaggtgc taggtgcttt aaactattaa aattcttaag aaataaggct actttttctg
    20341 ggtcttgttc atagtaggtg tggttctttt tttcgagtgt agcccatagc tttgag
//
LOCUS       DBERAE010000041        19633 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.41, whole genome shotgun sequence.
ACCESSION   DBERAE010000041 DBERAE010000000
VERSION     DBERAE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.41"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..611)
                     /locus_tag="ACL70N_001682"
     CDS             complement(<1..611)
                     /locus_tag="ACL70N_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGS0590445.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQL"
     gene            complement(720..1238)
                     /locus_tag="ACL70N_001683"
     CDS             complement(720..1238)
                     /locus_tag="ACL70N_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGS0590446.1"
                     /translation="MRTYENKEELKAEIEKTFEKYISEFDNIPENLKDKRVDEVDRTP
                     AENFAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1275..1403)
                     /locus_tag="ACL70N_001684"
                     /pseudo
     CDS             complement(1275..1403)
                     /locus_tag="ACL70N_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1465..2334)
                     /gene="rsmI"
                     /locus_tag="ACL70N_001685"
     CDS             complement(1465..2334)
                     /gene="rsmI"
                     /locus_tag="ACL70N_001685"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGS0590447.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2337..2654)
                     /gene="yabA"
                     /locus_tag="ACL70N_001686"
     CDS             complement(2337..2654)
                     /gene="yabA"
                     /locus_tag="ACL70N_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGS0590448.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2694..3584)
                     /locus_tag="ACL70N_001687"
     CDS             complement(2694..3584)
                     /locus_tag="ACL70N_001687"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGS0590449.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3581..4219)
                     /gene="tmk"
                     /locus_tag="ACL70N_001688"
     CDS             complement(3581..4219)
                     /gene="tmk"
                     /locus_tag="ACL70N_001688"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGS0590450.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4439..5236)
                     /gene="proC"
                     /locus_tag="ACL70N_001689"
     CDS             complement(4439..5236)
                     /gene="proC"
                     /locus_tag="ACL70N_001689"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGS0590451.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(5240..6502)
                     /locus_tag="ACL70N_001690"
     CDS             complement(5240..6502)
                     /locus_tag="ACL70N_001690"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGS0590452.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASFLPRLEQ
                     VLVAERKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6512..7621)
                     /gene="proB"
                     /locus_tag="ACL70N_001691"
     CDS             complement(6512..7621)
                     /gene="proB"
                     /locus_tag="ACL70N_001691"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGS0590453.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSAQVAAMVQ
                     ADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7722..9599)
                     /gene="cbpE"
                     /locus_tag="ACL70N_001692"
                     /gene_synonym="pce"
     CDS             complement(7722..9599)
                     /gene="cbpE"
                     /locus_tag="ACL70N_001692"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGS0590454.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSLISVVKVNG
                     KKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTS
                     DSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPSFQ
                     AGWHKSVYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFYLT
                     DSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQWYY
                     FAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKANDW
                     YFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKSAT
                     IKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSESE
                     Q"
     gene            complement(9602..10489)
                     /locus_tag="ACL70N_001693"
     CDS             complement(9602..10489)
                     /locus_tag="ACL70N_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0590455.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLSLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10479..10940)
                     /gene="lspA"
                     /locus_tag="ACL70N_001694"
     CDS             complement(10479..10940)
                     /gene="lspA"
                     /locus_tag="ACL70N_001694"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGS0590456.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10937..11845)
                     /locus_tag="ACL70N_001695"
     CDS             complement(10937..11845)
                     /locus_tag="ACL70N_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS0590457.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11838..12044
                     /locus_tag="ACL70N_001696"
     CDS             11838..12044
                     /locus_tag="ACL70N_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0590458.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLHYLPFSR
                     QSYFQNQFKKISGYTPLQYRKEKR"
     gene            complement(12096..12767)
                     /locus_tag="ACL70N_001697"
     CDS             complement(12096..12767)
                     /locus_tag="ACL70N_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0590459.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12821..13042)
                     /locus_tag="ACL70N_001698"
     CDS             complement(12821..13042)
                     /locus_tag="ACL70N_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGS0590460.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13313..14122
                     /locus_tag="ACL70N_001699"
     CDS             13313..14122
                     /locus_tag="ACL70N_001699"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0590461.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     NVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14303..15178)
                     /gene="aguB"
                     /locus_tag="ACL70N_001700"
     CDS             complement(14303..15178)
                     /gene="aguB"
                     /locus_tag="ACL70N_001700"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGS0590462.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15188..16273)
                     /gene="aguA"
                     /locus_tag="ACL70N_001701"
     CDS             complement(15188..16273)
                     /gene="aguA"
                     /locus_tag="ACL70N_001701"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGS0590463.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16270..17397)
                     /gene="nspC"
                     /locus_tag="ACL70N_001702"
     CDS             complement(16270..17397)
                     /gene="nspC"
                     /locus_tag="ACL70N_001702"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGS0590464.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17397..18656)
                     /locus_tag="ACL70N_001703"
     CDS             complement(17397..18656)
                     /locus_tag="ACL70N_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGS0590465.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18653..19513)
                     /gene="speE"
                     /locus_tag="ACL70N_001704"
     CDS             complement(18653..19513)
                     /gene="speE"
                     /locus_tag="ACL70N_001704"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGS0590466.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDREGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5663 a         4558 c         3500 g         5912 t
ORIGIN      
        1 tcaagctgtg agttcattat gatttgtaaa tccgatatat cttcagcagc taaaaacaca
       61 ttttgaaatg ttccaagtcc gttttcacca aagctatatt ctctcttact atacttactc
      121 ttattattct ctatatagtt agagtcaagg ttcttaacct cttgaagttc attttcttta
      181 cttctgaggt taaaatcttt tacttctgaa gttaagtttt ttgacttctg taagtcattt
      241 tcttttacct gaaatatact cataaagtct ttaacataaa tgatgttcgg cttaccaagt
      301 ccaagcctta ctctttcgat cagtcctatt ccttttttta catcaagctc atctaatgtt
      361 tttatggcag ttggctttga gatatttctt cttttcataa tttcttcgac agtaaaatag
      421 ataaatactc tgccttcctt gtctatccag ttattcttaa atgacattcc tgtccgttta
      481 agaagtatgg aataaaggat aattgcttct gctgataagc cccgaaattc ttctctatca
      541 actaatatct ccggtacttt taagaagtta aatctttccg cttctctgtt ataaaaatat
      601 tcaaagtcca tgcaagatca cctcccttct taaaaatttg caaagaaaaa gacgatagtt
      661 tttcttctat cgcctttggt aaccattttt atgaaatttt ttaaagttaa aaatataatt
      721 tataatacta tcttcttcca ttttctgatt ttagttctga aagttccaaa aggtgcaacc
      781 gtatttacat gaataaactt atacacttcc caagtcgctg ttttagtcgc ttcatcagcc
      841 cactttctca tatgcggttc aaataattct tcctcactca acgaatcaat cattgcagag
      901 atagaattaa tattttcatt taattttgct ttcaactctt gcagagataa atgagcgtag
      961 gtatctgtga accactgata taattcacca agttgattcc atttaaattt atccgatggt
     1021 gtttttactt gaagcccctt tctttcatct tcttcccatt taagaaccaa gttggtccag
     1081 ccaacctgat aagcaaagtt ttctgctgga gttctatcaa cttcatcaac tctcttatct
     1141 tttaaatttt ctggaatatt atcaaattct gaaatatatt tctcaaatgt tttctctatc
     1201 tcagctttta gttcttcttt attttcgtat gttcgcaaaa aatcaccttc tttctgattt
     1261 atcaatcctt tgatttaaaa tgaccttatt tttctattta taccttctag gaacgctata
     1321 actgctgctc caaccatcgg tattccgtat gggcttaata aaaaacttaa taccaaagct
     1381 tctataccaa gtgatacatc tttatattat catcactaat taagttaaac agaaacagac
     1441 agaattatta catcctgtct ccctttattg tttttcttcc cagtcgtggt aggcagcgta
     1501 gagctgactt ttattccact ggtaaatctt agcgacttcc ttgatagctt ggtttttctt
     1561 cacaccttgc tggatgcggg tttgaatttc tacgaacaag tcttcctcgt ccttttcctc
     1621 cacaccctga ctggcaccct caacaatgag aagacattcg cccttgagtg gcgtttcagc
     1681 aatgctttct aataactcag agatagtacc tcgttggtat tcttcataga ttttggtcaa
     1741 ttccctgacc aagacaactg agcggtcacc gtagacttct aacatatttt ccaacgtgtc
     1801 tgctacacga tgaggtgatt cataaaaaat ctgtgtttca ggataatctt ttttcaagcc
     1861 aaaaaattgc ttctgctgac ctgattttct cggtaaaaaa ccgtaaaaga tatgtggctg
     1921 tggcgctaaa ccactggcaa tcaaggcaga aattcctgca gaggcacctg gaactgtcac
     1981 aactgcaatt tcttcctcaa tagctgcctt aactaaatca tgaccagggt ctgaaatgct
     2041 aggcaaaccg gcatcagaga cctgagcaat actttgccct gctttcaaga aaccaatcaa
     2101 atcaggaatt ttttccttgg cattgtgctc atgaaaactg atctgcttgg tggaaatgtc
     2161 aaaatgcttg agcaaaagac ctgtattgcg cgtatcctca gcagcaatcc aatctacttc
     2221 tttcaaggtc tggatagctc gaaaggtcat atcatctaga ttgccaatcg gcgttgccac
     2281 tagatacagc ttgccatagg gagactgccc cttaaaactt ttttgaatct gcatgcctac
     2341 tccctgtata gcaactcgtc acaaaacata cattcctcgt cctgctctcg acgttgtcca
     2401 taaaaatcat tacatacgtg aaatccatca cggtaaatgc gacggacact ttcacgaaca
     2461 tgcttggcct tgacaggagc atctgcttcc acctcaccca agcgttctcg caacttacta
     2521 ttttccaagc gaagagctgt attttcctct accaggctct tgagattttt cttgatggct
     2581 tccacatcgg ctaaggttac caataattgt tgggaaaaat catccagcgc gtcaaataat
     2641 tcttttttgt ccataaaaca gccctttcct ttctttatca ttcatttttg agtttatatt
     2701 tctttcaaga ccagatattc catggcattt tgaaagctga cattagcttg ccacattttt
     2761 ctagcttcta gtaaatcttg tagaatcact cttactctta cctgcaagag gtcctgccca
     2821 cagagaactt caagaatccg taaaacctga tcctgttttt ccttatcatc tgccaagttg
     2881 gctaatttgg caacctgtag ataactttct tttttcttag ctactaacca agtcagcagg
     2941 cgttcacttt catcgaccaa ggtccaaaaa cttgcctgat gtgccaactt ttctgcttca
     3001 gctcgcgatt gactaaactt agctaaaaga gtcgcttttt tcttaacaag tcccatttgt
     3061 tctaagagta agataagttt ttcttcttgc tttttaaagt ggaagatctg agtccgactt
     3121 cggattgtcg gtaacatctt ttcctcatcg ctagtcaaga agaaaatata aacttcactc
     3181 tggggttctt cgatgacctt gagcagagaa ttggctgcgt tgggatgcat tttatccgct
     3241 tgctcgatga taaagacctg ttgctggctt tcaatccctg cttgagaaaa ctgtcccacc
     3301 aattcccgaa tgcgttctgt cttgatgacc tgattgactg gcttaatcaa ggtgacatct
     3361 ggaaactctt cctgttcaat cagcttgcaa cttcggcatt tctcacatgg taagacgcca
     3421 actttatccg tacaaaagag gctcttagct aaaaattgcg ccatttccaa gcttccaaag
     3481 aaacctgaaa agagataggc gtgattgagc tggtcttgtt ctaagatacg gacaaaacgg
     3541 tcaaactgag ctggttgcca agcctttagt tgatcttgtt tcatttggcc aagcccattc
     3601 cgtcaaacaa gacagccttg gtagtttcca caacttgctc caaagggaga ctagcatcaa
     3661 tcttgacaat gcgatttccc tctttatcca gaagagaaag gtagccttga cgaacttttt
     3721 tatgcaagtc caacccttcc aaatccaaac gattaacctc gcggtcacta ttagcagcaa
     3781 tacgagccag cccttcttcc acctcgatgt caaaatagag tgtcaaatcg ggtttgaggc
     3841 catctgtcgc aaactgattg agccagtcaa tggcttcaat atctaagcca cgaccaaatc
     3901 cctgataggc aacagaacta tcgataaaac gatccatgat gaccaacttg ccagcttcaa
     3961 gggctggaag aactttttcc accaaatgct gtctgcgact ggcaatatag agaagtagct
     4021 ctgttttagc atccatctga gtatgacttg gatccaaaat cacttcccga atcttctccc
     4081 caatcaagac tccgccaggt tcacgggtcg tcaacacctc tactcctttt tcctctaaaa
     4141 ttggtagcag agcctctaaa acactggtct tgcctgctcc ctctggtccc tcaagagaga
     4201 ctaaaaatcc ttttgacatg tctaactcat ttctttttta ctacttctat tctatcaaaa
     4261 aaataggggt ttgtgacaat ctttttgtct tctcatttca tactcaatga aaatcaaaga
     4321 gcaaactagg aagctagccg caggctgtac ttgagtacgg caaggtgaag ctgacgcagt
     4381 ttgaatttga ttttcgaaga gtatcaacca ccataaaaga ggcagataaa actacctctt
     4441 atttacctag ttcttgtgtt cgtttatagg cttgatgaac tgcctccatg actatgcctc
     4501 gaaaagcatg cgcttctagg cttgctacgc cagcaatagt cgaaccgcct ggactacaaa
     4561 cttgatcttt caaaactcca ggatgttgct ggctttctag gaccaattgc ccagctccta
     4621 ccacagtttg ggctgccatt ttcaaggctg tttctcgtgg taatcccgtc tgaacacctg
     4681 catctgccaa agcctcaata aagagataga caaaggctgg tccacagcct gcaagacctg
     4741 tcgctgcatt gattaagctt tctcctaatt caaccaagag accagccttg gataaaagct
     4801 gacaaaagag ctcactgtcc tcagccctgc aattaggaga caaggcataa ctaatcactc
     4861 cttgcccgat agaagcaggg gtattaggca tcatacgaat aattcggtgt tgacttggga
     4921 taagacttgc tagtttttct aaggtcaatc cagctgccat cgaaatcaaa agaagacttt
     4981 ctcttttttc aaggatggtc tggtattgag aaagcagttc agaaaactga gcaggcttaa
     5041 ctcctagaaa aatcacatct gcttctgcaa acatttcttc attgctggaa gcctgaccac
     5101 caaagtctgc aatgaaagca tctaccttag cttgactacg attggcaagg agaatctcat
     5161 ctgacgtcct agtctgcaag acagattttg ccaagctagc acccatattc cccaaaccga
     5221 taaatccaat cttcatctct tactccctta tctgcccatc accagtgacc acatacttgt
     5281 agctagtcaa ttccttcaag cccataggac cacgcgcgtg caatttctga gtagaaatcc
     5341 ccatttcaca accaagacca aattgtcctc catctgtgaa acgagttgag gcattaacat
     5401 acaccgctgc agagtccact tgatctgtaa agtatgctgc agcttcagca ttttccgtca
     5461 caatggcatc cgaatgatgg gtactgtggg attcaatatg cgcaaccgct tcttctaaac
     5521 tgctcacaac cttaacagct agaatatagt ctaaaaactc ggtatcaaag tcttgtgctt
     5581 gagcagcttg acctgaaaca aactggcttg ctttgctatc taggcggaat tgaattggtt
     5641 ccagtccagc ttccttacgc tctgcaacca acacttgctc caagcgagga aggaagcttg
     5701 ctgccttgtt ttcatgaacc agcagaacct ccatggcatt acaaacagaa ggacgactgg
     5761 ttttagcatt gttgatgata gacagcgcct tgtcttcgtc tgcatcctta tccacataga
     5821 catggacaat cccagtccct gtctcgataa caggtacaat cgcattctca accactgcat
     5881 tgatcaagcc agctcctcca cgaggaatga gaaggtctag atagcccttg gccttcatca
     5941 tagcataact actttcacgg ctagtatcct ccaccagttg aatcacattt ggatgaatag
     6001 tagtcgtctc caagcccttc ttcaaggctg tgacaatggc atgggttgtt tgataggcat
     6061 ccttaccact acgaagaaca accgcatttc cactcttaag agtcaaagca gccgcatcag
     6121 acgtcacatt tggacggctt tcatagataa taccgatgac acccatagct acacgttttt
     6181 ttgtgataac caaaccattt tcaagctgac ttgtttctaa aacttcaccg attggatctg
     6241 gtaaggcaac cacttcacga attcctcttg ccatcgcttc tatacgatct gcatccaaat
     6301 aaagacgatc caacatcaca tctgagattt tccccttagc cgctgccata tcgagggcat
     6361 tagccgctaa aatttcctca gtagcagcca ctaagtgatc agccatggct agcaaggctt
     6421 ggtttttcac ttcttcacta gctgtgttaa tcgatttttt aacagcctgt acctgttcaa
     6481 attgttcttg tctactcacc atagtttacc tctaaaattc tgtaaaaagt agttggattt
     6541 caggagtaat ggaaatccag tcgtcacggt aaatcaagac acccttggct ttttgagaac
     6601 gcaacatatc ctccaaagca gatgctccaa attgcacgcg tccttttcca agtgattttc
     6661 cactttcctt gtcaaatact gtcacgatat caccgtaaga aaagactcct tctgcttcaa
     6721 cgataccaga taagagaaga ctctttccat gttgagagag agcttccgca gcccctttat
     6781 caacccaaat agaaccttga ctctgagcat agaaggcaag ccattgtttc tgggtacgaa
     6841 gccccttctc ttgagcaaca aagtaagaac catcctcggt ctcctctgcc gcctcaatca
     6901 tggaatctga tttcaaggat gagcagatat aaacaggaac tcctgattcc gtcgcgatag
     6961 ttgcagcctt gattttggtt aacatacccc cagttccgtt tgacgaacca gctccaccag
     7021 ccatatcaat aatctcacga ttgatggtct cgattctctc caagcgtttg gctcttggat
     7081 ctgaattagg atttccagta tagagaccgt ccacatctgt caagagaacc aaaaggtctg
     7141 cttggaccat cgccgctact tgggcactta gagtgtcatt gtccccaacc ttgacctcat
     7201 caataacgac actatcattc tcattgatga taggaattgc cccacggttg agtaaaaccg
     7261 acaaagcctg atgggcattt ttataacgac gcttatccac aaagtcatct tgggtcagca
     7321 agatttgtgc agaaacgatt tgacgcaaga gaagattggt cgtatattct tccaacaaaa
     7381 gtccctgccc taccgctgct gaagcctgtt tatcagcaat cttagtcgga cgctttttaa
     7441 atcctaaggc tccaaaacca gccgcaatgg cacctgaaga caccaaaatc aactcatgac
     7501 cagcctcgtg cagcatagcc aactgctggg taatatcctt taccttacta cgtgataaac
     7561 ttccatcctc atttgtcaga gaagaagtac ccaccttaaa gacaatccgt ttgtatttca
     7621 tagtctcact ccgattattc atatttatcc attataacat gaataacagg aaatagaaaa
     7681 gagttgatag gaaaaagaag gccctaaaac cttcttttct actactgttc tgattccgat
     7741 ttgtttacac tcgtttcaga gctttgtgaa gttgaggatg tcaaatcttg actagttgaa
     7801 gaatttgtaa cactttcatg ttgactcgtt tctttatttt caagatcctt tttcactact
     7861 tctttggatt cttttatttc tgaatgactt gtagttttaa ttgtagcaga tttctcgatc
     7921 gaaacatcca ctaaccaggc accacttgaa tccacagtat agccttctgg tgtcttacca
     7981 ttcacaagta attgaccatt ttctttcaag aagtaccatt tatccttgtc cttgatccaa
     8041 cccacagctc gtgaaccgtc tgtcttgtag aaataccaat catttgcctt tttatgccag
     8101 ccttgcttca tagctcctga atcttccaga taataatgtt gaccagcaac ttctatctca
     8161 cctgtcttca tgacaccagt agaatccata tagtaccagg tttctttatc ttttacccag
     8221 cccattttca tttcccctga tggagcaaag taataccatt gccccatata ttgaagccat
     8281 cctgtcttca tagaaccatc aacatccaaa taataccact gctctttatc ttgaacccaa
     8341 ccaatttcca tctgattttc tttgttaaaa taataccaga ttccatcaat tttcttccaa
     8401 tttttagcag aagcaccaga gtctgtcaaa tagaaccaat gattgttcca ttttttccat
     8461 tgattctgta acaagatacc cgtttggtta aagtaatacc attcaccttc gatttcattc
     8521 caaccgacag catactctcc tgtagaatca ggcgcttgat accaccagtt cccatataca
     8581 ctcttatgcc aaccagcttg aaaacttgga atcggcttgt aggatgttga aatattgaca
     8641 aaaccgtctt ttcgaatatc aaaaactgtc gcatcatagt ctttgctggc tgcgttgatt
     8701 ctctcaattc ctcgttcttt gagccaatta acatactcac tatcaacacc atttttccaa
     8761 ggtagactat ccgaagtttg aacaatcaaa ctcggactca aatttttaat gaaatccttg
     8821 gtatttgatt tgttggtatc atggtgatga ttaaacttca tcaaatcaac ttttccaatg
     8881 agaggaccat acttgtcttc tgctccatga acattatcta aatcgccccc aaggtaaatt
     8941 ttcttgccat tgactttcac cacgctaatc aaggaattgt catcccaaat tttctttaat
     9001 tcacccgatg aatcagtttc attttcataa ttatagagct gaatatccat gtccccaaac
     9061 tgaaaatgag catccccttg tgtgatattt tgaataactg aaacacctgt ttctgcagca
     9121 gtctgtaaaa ccttatcata gccatacaga ttatcccata gacgttcaga attagtaata
     9181 cgactatcac tatatttctt aagatagact cggtcaactg gataggtaga cagtaattca
     9241 tcaacatttc caatatgatc actgtgggta tgggtcacca aaataaaatc aagtttttgg
     9301 acacccaatt ccttcaaacg acgaaagaca cggtctgtta gaacatgctt ataagacgtt
     9361 tcaattcctt ctctccatgg atagcgagaa tcacttccat ctgggaaatc ataatcttct
     9421 cctgtatcca ccatggcaaa atgtccattg ctttcaagaa taatcgcatc actgccacct
     9481 tcttgaacat tgataaagtg gattttattt cctgaacttt cttgagcctg aacattccca
     9541 taccatgaca aacctaaaaa agcgcctaca agtgctaaac tagttaattt ctttttcatt
     9601 cttactttct caatctctcc aaggtttcct taaaaatctc tgggatatct gctttaaatt
     9661 ccaaggtctt acctgttctc ggatgagtaa aacctaaagt cttggcatga agaaattgtc
     9721 catgtccttt caaagtcttg cgaggaccat agacctcatc accagcgact ggatggccga
     9781 tataagccat gtggacacgg atttgatgag tgcgccctgt ctccagttgc aactctacta
     9841 agctataatc gccaaagcgt tccaagacgt gaaaacgcgt cactgcaggc ttccctttag
     9901 cagttacagc ctgtttctta cggtcttttt cactccggcc aatcggcgct tcaattacac
     9961 cacgatcatt aggcagattt ccatgaacaa tcgcccaata tttgcggaga gactttttat
    10021 ccttgagttc ttgggcaagt gctagatgcg catcatcgtt tttagcaatc atgagaagac
    10081 ctgacgtatc cttatcaata cggtgaacaa tccctggacg cagaacccca ttgatacccg
    10141 acaagtcctt aatatgatac atgagggcat ttactagggt tccactggta tgaccagcac
    10201 tcgggtgcac aaccattccc tgaggtttgt taacgacagc cacatcctca tcttggtaga
    10261 ctatttctag cgaaagatcc tcagccacat actctaatac ctctggttct ggcacatggt
    10321 aagtgacgac atcaccctct tggactgtgt atttagcttt cttgacttga ccattgacca
    10381 agacctggcc tgatttaatt tgttcattcg cgagactacg tgataattct gacaaatctg
    10441 acaaagcctt atccaaacgc agaccaccag tttcaatttt aatttccatt tatttcctct
    10501 tttagcattg caatcaataa aataatcact ccaaccgtca gatagctatc tgccacattg
    10561 aaaattgcaa agttgataaa gtcaaggtgg aacatatcca caacaaagcc ctgactgacc
    10621 ctgtcaataa agtttccaag accacccgcg attattagag tcaaacccaa gaccatccag
    10681 aatgagtcct ccatgtgttt atgtaaatac caaatggcac ctatcacgac aaccagagta
    10741 atgacagcga ataacagctg ctgatcttgt aagatagaaa aggctgcacc tcgattttgc
    10801 aggtaggtca agctaacgaa attgggaatc caggagcgca cttcacccag tggaatctgc
    10861 tggacgatat aggatttgac caactgatcc agcccaatta aaagcagtac aatgactgcc
    10921 actattgctc tttttttcat gatttcctct tttgatcaaa atattcttgc atgacttcta
    10981 cgaagagagt cccagcttga ctaagctcca cttcttcacg tttaacatag accatgcggt
    11041 tatctaggtt atccttgaga cgaataactg taatgccatt aacactgtca ctatctaaaa
    11101 atccagaacc tgtcgcatag gcgtccgtcc gctccaaaat accattcaag gtggcacggt
    11161 ctgtcacatt aaacatctgt gagctagcgc tggtatcgac aaagttctct gaataataaa
    11221 ggtactcgtc tttctcttga gtgaaacgaa ccgttggtaa atccgctaaa tcctccatga
    11281 ctaattcctc tttctgggct aaaggatgac cctcacagag ataaatatgg gtatggaaag
    11341 gaatcaattc gatgacctcc agacctaact tttcaacccg ttgcataatc ccctttttat
    11401 tttgattgtt gaggtagata atcccaatct cactatgccc ttgcgccact tcatctaata
    11461 tttgaacagt agttgattca aaaatacgga agttcttata gtcaggatag cgctctgaaa
    11521 aggccgtaat agttggtggt aagaagtcat agtgctggct agcaacggaa aattcatctt
    11581 tttcttcttc aggattggca tactgatttt gaaaaatatc aaatccttta accaattctt
    11641 gcgctttttc ataaaattcc atcccacgac gggtcaagaa agtccctgag ctggtccgac
    11701 ggaaaatctt aaagcccaac tctttttcca aatcacgaac agaaatagac agactcggct
    11761 gactaacata catcttttca gcagcttcac gaaaagtacc actattggca atagccacaa
    11821 catagcgtaa ttgttgaatg ttcatcttct acccccaact tctttatctt ttcattatac
    11881 catattttag aagttttcca aaaaggaaaa aagaacatcc tattcttctt aactatcttc
    11941 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
    12001 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
    12061 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
    12121 caaacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
    12181 tttttagtca tgcgatacaa tagagctaaa atcagacctc cactagcata aatgaaaaaa
    12241 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
    12301 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
    12361 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
    12421 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
    12481 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
    12541 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
    12601 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
    12661 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
    12721 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaatcctctg
    12781 ttttctcccc ttgtttcttc atattcctaa taaattttac ttaaaatctc gcagcacttc
    12841 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
    12901 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
    12961 ttttaccata gggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
    13021 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
    13081 atctactact catacctact tacaaaaaaa ctattttaag ctagtttttt tatgcttgtc
    13141 tagttgcaat attgacaagt ttagtatatc atatctttgc caaatatcct cttcaaatct
    13201 tgaattgtca tcgaaacgtc ctaaactgca aaatcaatta gtctcaagct ttctatcaat
    13261 ttcttctcca aaatatgcta taataatagc aaaagataaa gaaggaagac ctatgattaa
    13321 actactagcc ttggatatgg acggcaccct cctcaatgaa gccaaggaaa tcccacaagc
    13381 tcacattact gctattcaca aagccattga aaaaggtgtc aaactggttc tctgtacggg
    13441 tcgccccctt ttcggtgtcc tcccctacta caaaaaactg gggcttgacc tccagaacga
    13501 atatgttatt gttaacaacg gttgttcaac tcaccaaacc agtgattggg gtctagttga
    13561 ctggaaagaa ctgagtccag ctgacatcga atacctctat gaccttgctg aaaagagtaa
    13621 tgttcagttg acactttttg acgagtcaca ttattttgtt ctcggtggca agcccaatca
    13681 agttattgaa aatgatgcta aactagtatt ttcagacctg actgaaattt ctcttgagga
    13741 agcgactagt ggaaagttcc ggatgttcca aggtatgttt ttaggaacaa aagaacaaac
    13801 agacgatttt gagcagcgtt ttgctgaaga gctttgccaa cgattcagtg gagttcgttc
    13861 gcagcctgtc atttatgaag caatgccact tggaacgaca aaggctactg ctctttcacg
    13921 actagctgag attttgaaga ttgattcctc agagattatg gccatgggcg atgctaataa
    13981 cgatatcgaa atgctccagt ttgcagggct tgggattgca atgggaaatg ccagcgatta
    14041 tgtcaaatct cttgcggatg ccgttacctc aagcaacgaa gaagacggcg ttgcgcgtgc
    14101 tattgagaaa tatattctat aaaaaagaaa agcaaataga cagaagttac tgctatttgc
    14161 ttttttgcta atattttaaa atacggacta atcaatagac aagaatagcg aatcataaaa
    14221 atcgatttac tagatgccat agtatcttat agttgctaat aagaagttag tctagcagaa
    14281 tgaatctctc atttctccca cactaatctg taatttgtct atacatttct ggtcttctat
    14341 ctcgaaacaa gccccagttt aggcgttcac tcgctccctt gtctaggtca taagtagcta
    14401 acagaacagc ttcttcttgt ctttcagctc gttctagaat agctcctgtt tcatccgtca
    14461 taaaggagga accgtagaag tcaagactgg aactctgtcc gccattttcc tcactaggag
    14521 taacctcctc taaaccataa cgattggctg cgatgactgg aacaatattc gctgctgcgt
    14581 gcccttgcat agtacgttgc cagtgaccac aactatctgt atccaaaatc ggctctgaac
    14641 cgatggctgt tggataaaag agcaattctg ccccattcag agcaagacag cgggctgttt
    14701 cggggaacca ttgatcccaa cagataccga taccaatctt agcatagcga gtattccaga
    14761 ccttgaaacc agtgttacca ggcgtgaaat agaatttttc ttgataataa tggtcatctg
    14821 gtatgtgggt ctttcgataa acgcccagca cttccccatc tgcatcaata acggcaatag
    14881 agttatacaa gacattacca tctttttcat agaaactgat tggtaaaaca acttgtagtt
    14941 ccttagcaat caccttaaaa tgctgaatgg cagtattttc cgctacagat tgggcatact
    15001 ggtagtagtc atactgacgt tcctgacaga aatagggatg ttcaaacaac tcgggcaaga
    15061 gaataatttg ggctccttgc tcagcagcct gacgtactaa acgctctgcg gtttggatat
    15121 ttgttgccac atccttagcg cattgcatct gaatggttgc aactcttaca tttctcatct
    15181 ttttctccta ttctggaatt tgttgggtga tacagtggat attgccacca cctaagagaa
    15241 tatctctggc tggtattccg acaactttac ggtctgggaa acacttgctg aggatatcta
    15301 aggccacttg gtcgtttaca tcctcaaact gtggaaccaa gacagccttg ttggcgatat
    15361 aaaagtttac gtaggaagct gctagtcgtt cacctgcgta tcgcttttct tctccttctt
    15421 catagatgta gcctggcaaa tcttcttctg tcacaacttg tcgaactgca gggataggca
    15481 atttatgaat ggtgaagtga caaccttttg catctgtttc ctgttctaag agttcgagat
    15541 ctgcttttga catggcatac tggggatcat tttcgtcatc tgtccaagct aaaacaacct
    15601 cagcaggacc aacaaaggca gcaacattat cgacgtgttc attggtttca tcctgataaa
    15661 taccataagg aagccaaata actttttcag caccaagact ttctaataat gtgttttcaa
    15721 tctcctcttt agtcaggtta ggattgcgac caggactaag caagcaactt tcagttacga
    15781 gaatagttcc ttgaccatcg ctatggattg cgcctccttc cagtacaaaa ggtttagcat
    15841 catagacagg cttttccaag gcctcagcaa aacgactggc tacttggtca tcctcttcat
    15901 aatcttgata aagaccatca taggtgcctc cccaagcatt gaaggcccaa tccacggcta
    15961 atttcttacc tttatcattg acgagaatgg ttgggccagt atcacgcgcc caggcatcat
    16021 tggtgggaat gtctaaataa acaaccttgt ctccaagata ggattgggct tcagatagat
    16081 aggcctgctc caccaaaaga tagactcttt ccccttctgc tatggtctcg atgatctgag
    16141 taaatgatct tttagcagcc tttccttgaa aaggccatga tcctggtcga gtcggccata
    16201 tcatgagggt accatgatgg ggttcgtact ctgctggcat gtgatagcct aatttttttg
    16261 gactgtccat catgataatc tccctttaaa gtcttgatag ccaaaagctt tgagtaagct
    16321 acagtctccc tgttcgtcca tgagatagag acttggcaat ccaataccat taaaggtatt
    16381 atttttgaca aaagaataaa tggccatgtc ttgaaaataa agtctgtctc cgatttggac
    16441 tggattttca aaactataat caccaatcac atcgcccgtc agacaggtat tagaagaaag
    16501 tctgtaggta tgggcttttt cctgtgcctc aaagccattt ctcaaaggtg gacgataggg
    16561 catctcaagt acatcaggca tatggcaggt cgcagaggcg tctaaaacca agatttccat
    16621 accattttct acaatatcta atacctcagt tgctaaataa cccgcattaa gcgcaatggc
    16681 ttcaccaggc tcgatataga tttcaagatt gtaagttttt cggatacgct tgatttctga
    16741 aatcagcaaa tccacatcgt aaccttctct tgtaatatga tgaccaccac ccatattgag
    16801 ccattttacc tcatgtaagt agggaccaaa ctgttcttct actgctttca aagttgtttg
    16861 taaatcatct gctccctgct cgcaaagggt atgaaaatga agtccgtcaa ccaaatctag
    16921 caaatcactc ggaatcttgt ctatagtaac tccaaagcga gaaccaggtg cacaagggtc
    16981 atagagcgcg tgatctcctt gagttgaaca ctgagggttg aggcgcaaac caacactgac
    17041 accagcctct cgacaacgag ccccatgctt acgcaactgt ctctctgagt taaagacgat
    17101 atggtctgtt atcccaagca attcctccat gtcctcatcc ttgaaagctg gtgcaaaaac
    17161 atggacttca ccaggaaatt cttcccttgc caatttggcc tcatagagtc cactagctgt
    17221 cgtacctgat agatactggc taatcaaggg ataagttttg tagagggaat atgccttctg
    17281 ggcaagcaag accttgcaac cggcctcttc ttgtacatat tgtagaatgc ggcaattagc
    17341 ttctaacttg gccaagtcaa taacataggc tggtgttggt acttgttcta acttcattag
    17401 tccaccattt gtggattttc aaccacaacc catggcaaac catactcatt caaagcttcc
    17461 atgaatggat ctggatctaa ctcctcaagg ttatacactc cagcttgttt ccaagttccg
    17521 ttcatgacta attttgtccc aatcatggct ggaactcctg tcgtataaga aatagcttgc
    17581 gaaccaacct ctgcgtaaca ttcctgatgg tcgcagacat tgtagatata gatagtcttt
    17641 ttgacaccgt ctttgacacc tgtaaagata catccaatat tggttttacc tacagtacgt
    17701 ggaccaaggc tagcaggatc tggaagcaag gctttcaaaa attgaattgg aacaatttct
    17761 tggccgttaa agttaatggt atccgtacga aggagtccaa cattttcaag acatttcatg
    17821 tgcgtcaagt aagattgacc aaaagtcata aagaaacgaa tgcgtttgac tccaggaatg
    17881 ttcttggcca gcgattcgat ttcttcatgg tgaaggagat acatatcttt ttgtccaact
    17941 tgagggaaat catactcacg cttgatagac atagcttcga cttcgaccca tttcccatct
    18001 tcccagtaag aacctggcgc agaaacctca cggagattaa tttctggatt aaagttggtt
    18061 gcaaatggat aaccgtggtc accgccatta cagtctaaaa tgtcgatata atggatttca
    18121 tcaaaatagt gtttgagggc ataagctgaa aagacactag ttacacctgg gtcaaaacca
    18181 gaaccaagaa gagcagtcaa gcctgcttct ttgaatttct cttgataagc ccactgccat
    18241 gagtagtcaa agtaggctgt aaaaccaagt tccttacaac gtttttcgta gatagcacgc
    18301 cactcagggt cttctgtgtc ttctgcttcg tagttggctg tatcgatata gtgaacacct
    18361 gttgccaaac aagcatccat aatggttaaa tcttgataag gcagagctac attcaaaaca
    18421 gcttctggtt tgtagctttc aatcagggca atcacttctt caaccttgtc agcatcaagt
    18481 gctgcagttt caattttagt acttgttttg ccttctagct tcgctttcaa gtcatcgcat
    18541 tttgacttgg tacggctagc aatcataatc tctgtaaatg tttcgctatc ttgacaaatc
    18601 tttgaaatag caacttgggc aacgccccca caaccaataa ctagtaaacg actcattttt
    18661 ttccttcctc ttcttctaaa atgtcctcaa catacttggg caacataaag gatcccacgt
    18721 gtaagtttgc agtgtagtat tctgtgaaaa gctggcgttt tttccaacct tccctgtcaa
    18781 aatctttgac agggtggtat tttttcgatg caaatccaaa caaccaatag ccagctgggc
    18841 tagttggaat atgggcctga taaacccgac tgattggaaa ggcttgattg accttgcggt
    18901 gcatgcttcg gcaggccgac tcatcctcgt caaagaaggg actcccatgc tggtaaatca
    18961 tgatgccgtc ttccttcaga gctcgataac tattgccgta gaattctttg gtaaagagtc
    19021 cttccgtatg gccaaatgga tctgtcgcat cgttgatgat aatatcgtaa tcatcttcgc
    19081 agtttcgcaa aaagcgtagc ccattttggt agtaaatggt aacacgagga tcatctagcc
    19141 ctgcagcaaa gtctgggaaa tactcacgac agacctcgac caacatttca tccggttcca
    19201 cgatatcgat ttgttccagt tcaggataga gtgttaatac ttgggcaaca ccgccgtcac
    19261 cacccccaat aaccaatact ttctttggat ttgggtggac agccatggga acgtggacgg
    19321 tcatttcatt gtagacgaaa tcatccgcat ctgagaacaa gacatggcca tttaaaatca
    19381 gtattttccc aaaagctggc gtatccaaga cttcgatatc ctgccattca ctttttccag
    19441 cgtaaagttg cttggctgtt ctcagagaca atttgacatc tggagtatga acttcagaaa
    19501 accataaatc catctatttc tccttatatt atatttagcg cagttagcta ctgccaaagc
    19561 ccaagtggta tacttggaat aagccactgt ggattagttc atttcctcca atcgcttgac
    19621 gatttccgaa agg
//
LOCUS       DBERAE010000042        18952 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.42, whole genome shotgun sequence.
ACCESSION   DBERAE010000042 DBERAE010000000
VERSION     DBERAE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.42"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            174..512
                     /locus_tag="ACL70N_001705"
     CDS             174..512
                     /locus_tag="ACL70N_001705"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGS0590467.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            702..2138
                     /locus_tag="ACL70N_001706"
     CDS             702..2138
                     /locus_tag="ACL70N_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS0590468.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2190..2429
                     /locus_tag="ACL70N_001707"
     CDS             2190..2429
                     /locus_tag="ACL70N_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGS0590469.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2559..2873
                     /locus_tag="ACL70N_001708"
     CDS             2559..2873
                     /locus_tag="ACL70N_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGS0590470.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2991..4970
                     /locus_tag="ACL70N_001709"
     CDS             2991..4970
                     /locus_tag="ACL70N_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0590471.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            4980..5294
                     /locus_tag="ACL70N_001710"
     CDS             4980..5294
                     /locus_tag="ACL70N_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGS0590472.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5325..5831
                     /locus_tag="ACL70N_001711"
     CDS             5325..5831
                     /locus_tag="ACL70N_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590473.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFENLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5911..7257
                     /gene="celB"
                     /locus_tag="ACL70N_001712"
     CDS             5911..7257
                     /gene="celB"
                     /locus_tag="ACL70N_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGS0590474.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNSLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7637..7813
                     /locus_tag="ACL70N_001713"
     CDS             7637..7813
                     /locus_tag="ACL70N_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590475.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALSLGMT"
     gene            8215..10428
                     /locus_tag="ACL70N_001714"
     CDS             8215..10428
                     /locus_tag="ACL70N_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGS0590476.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEDEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10650..11126)
                     /locus_tag="ACL70N_001715"
     CDS             complement(10650..11126)
                     /locus_tag="ACL70N_001715"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGS0590477.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTNPKQIEEAIQTLL"
     gene            11349..14552
                     /locus_tag="ACL70N_001716"
     CDS             11349..14552
                     /locus_tag="ACL70N_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGS0590478.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSTWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDIASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKSGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14932..15308
                     /gene="tnpA"
                     /locus_tag="ACL70N_001717"
                     /pseudo
     CDS             14932..15308
                     /gene="tnpA"
                     /locus_tag="ACL70N_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458050.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            15490..15552
                     /locus_tag="ACL70N_001718"
                     /pseudo
     CDS             15490..15552
                     /locus_tag="ACL70N_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15696..16325)
                     /locus_tag="ACL70N_001719"
     CDS             complement(15696..16325)
                     /locus_tag="ACL70N_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGS0590479.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16335..17336)
                     /locus_tag="ACL70N_001720"
     CDS             complement(16335..17336)
                     /locus_tag="ACL70N_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGS0590480.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17367..18008)
                     /locus_tag="ACL70N_001721"
     CDS             complement(17367..18008)
                     /locus_tag="ACL70N_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGS0590481.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18027..18842)
                     /locus_tag="ACL70N_001722"
     CDS             complement(18027..18842)
                     /locus_tag="ACL70N_001722"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGS0590482.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6133 a         2968 c         3928 g         5923 t
ORIGIN      
        1 tgctcttgtt tcaattgact ataaatcgct ataagaaaaa atcattttat tggtataaag
       61 aagtgattga aagtaatggc gaaacgttag ataattagtt cataaaaaac aagtttagat
      121 cctcatctaa acttgttttt ttaaaattga aggatgattt tggaggatat aagatgacat
      181 tgactattca tgtatattat aaaggtgatg gagatagtgc aataaagttt gcaagagaaa
      241 tgcttgatag tggccttgtt aaagaaatta gaaatcaaaa aggtaacttg aaatacgaat
      301 attttttacc aattgaaaaa gagggaacta ttctccttat tgatcagtgg ataaatcaag
      361 aaactttaga taaacattat caatcaaaga caatgcagaa aatcttagat ttaagaaaaa
      421 aatatcactt gcagatgcaa gttgaacgtt atatagaaga tgattctggg atgccagaaa
      481 gcgataagtc gtttatagac acagggaatt agaattattg tgagagtttt tgtagtttga
      541 aagtattgaa aatcgtaaag atatcattac gagaatacaa gaagatattg ttctatttcc
      601 attaaaaatt acttctttcc ttaacaataa ggaaaaagaa tgcgttttca tcttttggtt
      661 taaggtttat aataagagta tcaaagtcag gaggaaaaaa gatgactact tttaaagatg
      721 gatttttatg gggtggtgct gttgctgctc atcaacttga aggtggatgg caagaaggtg
      781 gcaagggaat tagtgttgct gatgttatga ctgctggtcg tcatggagta gctcgtgaaa
      841 ttactttggg agttttagag ggtaaatatt atccaaatca tgaggcgata gatttttatc
      901 atcgttataa agaagacata gcactttttg ctgaaatggg attcaagtgc ttccgtacct
      961 ctattgcatg gacacgtatc tttccaaaag gtgatgagtt agagccgaat gaagaaggat
     1021 tacagtttta tgataatctt tttgatgaat gcttaaagaa tggtattgaa cctgtcatca
     1081 ctctatctca ttttgaaatg ccttatcact tagtgaccga atatggtggt tggaaaaata
     1141 ggaaattgat tgatttcttt gctcgttttg cagaagtcgt atttaaacgt tacaaagata
     1201 aggttaaata ttggatgact ttcaatgaaa tcaataatca agcgaattat caggaagatt
     1261 ttgcaccatt tactaactca ggtattgtat atgaggaagg tgataataga gaagcaatta
     1321 tgtatcaagc agcacattac gaattagttg cttctgcacg agctgtaaaa attggtcatg
     1381 agattaatcc agattttcaa ataggttgta tgattgcgat gtgtccaatt tatccagtta
     1441 cttgcaatcc taaggatatc ttaatggcaa tgaaagctat gcagaagcgt tattattttg
     1501 ctgatgtgca tgttttaggt aaatatcctg agcatatttt caagtattgg gaacgaaaag
     1561 gtatttcagt tgattttact gaccaggata aagaagattt acttggtggg actgtagatt
     1621 acattggttt cagttactat atgtcctttg ctatagactc tcatcgtgaa aataatcctt
     1681 attttgatta tcttgaaaca gaagatttag tgaaaaataa ttatgttaag gcttctgaat
     1741 gggagtggca aattgatcca gaaggtttac gttatgcgtt aaattggttt acagaccact
     1801 atcacttacc actctttatt gttgaaaatg gttttggagc tatagatcaa gttgcagcag
     1861 atggtatggt acatgatgat tatagaattg aatatctagg tgcccatatt cgtgaaatga
     1921 aaaaggctgt agttgaagat ggtgttgatt taatgggtta tactccatgg ggatgtattg
     1981 atttggtttc agctggtacc ggtgaaatgc ggaaacgtta tggttttatt tatgtagata
     2041 aagatgataa tgggaaggga agttataatc gttccccgaa aaaatctttt ggctggtata
     2101 aggaagttat ttcatctaac ggtgaatcag tagaatagta taaacaaact gagattattc
     2161 tcagtttgtt tagcatattg aggtgacata tgattggaag tattgcagca attttaacaa
     2221 catttgcatt tttaccacaa gtttttcgtg tagttaagac aaaggacaca ggatctattg
     2281 ctctaggtat gtatgttatg caagttattg gtattgcatt gtggcttgct catggtattc
     2341 gtataggaga cttgcctttg attttagcaa atagtgtttc atttctactc tcaggaataa
     2401 ttttatttta taaattgaag tataaataat ttttttccat atcatttagg aaaatgaggg
     2461 aattgtcatt ggaaacgctt tattttataa taaaaataga taacaaataa gccaacttag
     2521 cacagctttg attggattta agaaaaggag aaaatattat ggcaaaagct ttaattattt
     2581 gtgcagcagg aatgtcttca tcacttatgg cacagaaaac aacagagttt ctaaaaggaa
     2641 aagggaaaga tattgtagtt gatgctatta gtgctactga aggagggaaa gctatcgcag
     2701 cagcagcttt tgatttgtat cttgtcagcc ctcaaacaaa aatgtacttt aagcaatttg
     2761 aagaggctgg ttctaaagca ggaaaaccag ttgtacaaat acctcctcaa gcctatattc
     2821 ctattccaat gggaattgaa aaaatggcta atttgattct tgagaatatt tgatgaacac
     2881 atgaaatgtc aataaatatt taagttaaga taaattgttt tgagtttgat ataaattgat
     2941 ttaagtgtat aatatgcttc aatatatgaa aacatacgtt ttaggaggga atgaatgtgt
     3001 taaacattaa agagaaagat atccttcaat ttttaataaa aaataaggaa cgttttgtta
     3061 caagcaaaga actggcagaa tatttatcct gttcagatag aactgtccgt aatgtactga
     3121 aattaattga gaagacaatg attattcaag gagtccggtt gatttcaaaa caaggtcaag
     3181 ggtatcaaat attttttgag aatcaaggcg cttaccagga gtttagacaa acttatgaac
     3241 tggaagaaga ctatacgaaa actgcggttt caaaaggtga tgatcgttta gtatttatct
     3301 taaataaatt attatttgag caagttccag ttctttttga tgatttagct gatgaacttt
     3361 acgttagtcg ttcaacatta tctcatgatt tcagaaagat acgagtgatg ttatcagagt
     3421 ataatttgtc cattgagagt agggcgaata aaggagttta tgtctcaggc gaggaacgtg
     3481 ataaacgacg ttttatcata aattatttcc tagagaatca attttttaaa acaatacatt
     3541 gctatgtaaa atttaacttt tttgctcaaa ctgttccatt agaagaattt gctagaattg
     3601 ttttggatga atgccaagag gccaacctaa aactatctga ttttgtacta cagaatttag
     3661 tagttcacat agcattgtct gtgattcgtt taaaatccgg atttgaaata aaaaatatag
     3721 actgtcagat gactgatgat gcaatagaga gaaaggttgc tcaaagaatt ctttctaaag
     3781 taagagaagt aacaaatcag gaatttccag ttcaggaaat agactacatt actttgcatt
     3841 tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa tatttctgaa gaagttttaa
     3901 aaaaatcttt atttaaaaca tttcagaatt taggattaga tgatatgtat aacttttctt
     3961 cagatttcca actaattgaa ggattgataa ctcatctaat gacactacaa gtacgtttag
     4021 aaagccggat taccttaaat aaccctttgg tagatgaaat taaacagaat tatagtgata
     4081 tattctttat gactagagaa attcttgcaa atatggacaa gttcttggag tggacaatat
     4141 cagatgatga agtagcatat gtaagtcttc actttttagc tgctatggaa cgtagcaaag
     4201 agagtactaa gtttaatatt cttgctattt gtgcaacagg atttggtgca gcccaaatgt
     4261 taagaaatcg tttggaaacg gagtttggga agcgagtaga agttgttgat gtaataggct
     4321 attatgaatt gaatcaagaa aaacttaaag gaatagattt tatagtgtca gctgttgatt
     4381 tatcaaatct atattttcaa attccagttt ttaaagttag tgtgtttctt aagagtgatg
     4441 agatggaaat gattagaaaa gctatggatc agatgcaagt ttctagttat gtacaatcat
     4501 caaagattaa taaatttgaa aacaacagct ttagacagta ttttagtaaa gaaaattttt
     4561 taatatgtac tgaatcagac aaggtaaatt tacttgaaaa gatggttgag agtttatctg
     4621 ttggtgaatc aaatgagttt gaacaatctt tactttatgg aattaaacag cgcgaagaat
     4681 taagttcagt tgttttttct gaaaaaattg cagttccgca tcctattcag ccctttggta
     4741 cagagggaaa ggtttcggtt gcaatttgta aagattcgtt actctgggat aatcaaagtt
     4801 catatgtcca gctagtattt cttctatctc catcaatata tgggaacgaa ggtttggcaa
     4861 ctgtgactaa aaagatagtc tctctgacag agaatgatga attgcaaaat cagctaatat
     4921 cttgcaataa ctttgaagat tttattaaca tatttgagaa gataaaatag gaggttcata
     4981 tgaatcaaga ggaactgcag gttgcagcat ttgaaattat tctgcattcg ggaaatgcaa
     5041 ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg tagttttgat gatgcagaaa
     5101 gtaaattaaa tcaatcaaat gagataattc ttgaagcgca tcatgcacaa accaaactct
     5161 tgcaagaata cgcaagtgga gtggaaatta aaattgaaat tatcatggta catgctcaag
     5221 accatttaat gaccactatg acattattag aagtagcaaa ggaaatgtta gctctttata
     5281 agaaagttaa ctaaatatgt gttgttatat aaggaggaaa tgatatggat aaaaaagaac
     5341 gacaaaaaat tgaacaacaa cgtcgagaga tggctctaac taatactttt tttaatcgat
     5401 atcttcttct acgttattca atagcactct tcttttttgg gaatatttat tggcttttga
     5461 atcagtttat tagtccctcg cctattatta ttttccccat tatgctcata gtattttcta
     5521 ttttagcaac tattgaacaa tttaaacttt atggaaatag gaaagaaaag ttgggaataa
     5581 cactaatgtt tgttagaata caaatgctta tttcaatagg attacttgtt ttaacttgga
     5641 caagttggtt tgagaatctt tttccgattt ttgaaaataa ccaagtagca cgtttatttg
     5701 tttttgtagt tcttctatta ggtttagttc tgagtttgtt agacattaga agaattaaaa
     5761 aaatttataa acgaacagat aaggcttatc aacaatttgt ccaattggaa aagaactcac
     5821 ttagtttata atcctgaact agtataattt gtatttgaaa ctagtcttta aaaagtaaaa
     5881 attattatgt tttattaagg aggtctattt atggatcaac aaaacgggtt gtttggtttt
     5941 cttgaaaacc atgttatggg accaatgggc aaacttgctc agtttaaagt agtgcgtgct
     6001 atcacggctg caggtatggc tgctgtacca tttactattg taggatcaat gtttttggta
     6061 ttcagtattt tgccacaagc tttctcattt tggccaattg tggcagatat tttctctgct
     6121 tcatttgata aattcacatc actttacatg gttgcaaact atgcgactat gggttctcta
     6181 tctctttatt tcgttctatc acttgcatat gaattgacaa aaatttatgc agaggaggaa
     6241 gaactcaata tgaattctct taatggtgcc ttgctcgcct tgatggcttt tgtcatgaca
     6301 gtaccgcaaa tcatttttga tggtggaatg atgaagactg tgacaagtct aaaagaaggt
     6361 gcagtaattg cagatggatg ggcaatggga aatggagtcg cacgttttgg tacaacagga
     6421 atttttaccg caatcattat ggcaattgtg actgttctta tttatcgtat gtgtgttaaa
     6481 cataattggg ttattaaaat gcctgaagct gttccagaag gagtttctcg tggatttacc
     6541 gctttggttc cgggatttgt tgttgcattt gttgttatct ttatcaacgg tcttcttgta
     6601 gcaatgggaa cagatatttt taaagtcatt gcaattccat ttggttttgt atccaatctg
     6661 actaattcgt ggattggttt aatgattatt tatctattga ctcaactact ttggattgta
     6721 ggtatccacg gtgcgaacat tgtttttgca tttgttagtc caattgctct tgctaacatg
     6781 gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg aattttctaa tatgtttgta
     6841 attgcaggtg gttctggtgc aactttagga ctatgtttat atattgcttt tgcctctaaa
     6901 tctgaacagc ttaaagcaat aggacgagca tctgtagttc cagccttatt taatattaat
     6961 gaaccattaa tttttggatt acctattatc tataatccag ccttggctat accatttatt
     7021 ttagcaccaa tggttactgc tactatttat tacgtagcga attctctaaa ctttattaag
     7081 ccaattatcg cacaggttcc atggccaact ccagtaggga ttggagcttt cttagggaca
     7141 gcagatcttc gagctgtatt agttgctcta gtatgtgcat ttgcagcatt cctagtctat
     7201 cttccattca tccgtgtata tgatcaaaaa ttggtgaaag aagagcaagg tatctaataa
     7261 gtaaaaaagt atactcgatg atagaatcca tatagtttaa ataatgagcg ttaacattag
     7321 cagtgaagag gtctttttaa gatattcttc tctgcttttt catatttttt cgctatgtag
     7381 agtatgaagc aaaatagaaa gtagttcgaa tagttgataa acagggaatt gctgttattt
     7441 aaaaaaaaca ataaagtaaa gtatgttatc gtagaatacg atacaatagt aaaaaagcaa
     7501 aaagaatgcg ttttatattt gggtttgagg cttataaaat aggataagcg tactgaaaac
     7561 ttagatatga caaacaaaat aaaattttta aaagctacag agaaacatgg tataatgtat
     7621 ctaaaggagg tagcatatgt ccttagatat agataaagaa aagatgacaa tcatgggaat
     7681 agcttttgaa aaccgatccg tttttaagag tgtttggtat gctttaagta caaatatgat
     7741 tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag ctctttctct
     7801 ggggatgact taatgaagcg caactgttat gagtcttatg actatgttga tccggataat
     7861 ttatataccg atccgggttc ttcagttcta agaaataagc aggaaggaaa aaagcacgcg
     7921 agcttgaata tcgtatgatt gctagtaaga gtttgaaatt atttatcaat cctatcttag
     7981 ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt tgaaaagtga
     8041 taactcttta ataaactctt ggtttgttaa aagatatttt gtccactaca tttttttcaa
     8101 ttgactatta tttgtcatag atataacaga tagaacattg cattcagaat aatgaaaaac
     8161 gcatcaaaaa tggtgcgttc tgtttttatg ctaccataaa aggaggaaaa caaattgaaa
     8221 atttttaagg gagagtttta tcgaatctct gtattaacag acaagctagt aaggttagaa
     8281 tactctcgaa ctggaaattt tgaggataga acgacacaac ttatctataa tagagatttt
     8341 ggccaagttt cgttagatta tatcgagaca tcaaatgtac tagatattat gacggactat
     8401 tttcatctgc actttaataa aggagaattt aacgccgaaa atttatttat agaattaaaa
     8461 ggaaattttg ccgtatatgg tagtcgctgg tattttggtg aatctattga aacgttaaaa
     8521 ggaacagctc ggactctgga taaggcagat ggagcaatct cgttagaaga tggaattatt
     8581 agccgaaatg gtatagcctt attggatgat tctcaaggat ttatttggga tgaacaatct
     8641 ggttatattg agagagaaaa tcaaattgac ctgtatttct ttgcctatgg gcatgattat
     8701 agaggagcaa tcagagactt ttaccatttg actggttcaa cacccttgtt gccaagatat
     8761 gctttaggca attggtggag tagatattgg ccttatacgt cggatgaata cttggattta
     8821 atagacagat ttgaaacaga gaaaattcca ttatctatcg gtgtgttaga tatggattgg
     8881 catataactg acattccagc tcgttttgga agtggctgga caggatatag ttggaataga
     8941 aacttaatac caaatccaga acagttattg caacaacttc atgatagaaa gttaaaactc
     9001 tccttaaatg tccatcctgc tgatgggata cgggcttatg aagaagctta tcctcaaatc
     9061 gcaaaacggt tggggttaaa tgtagaacta gaagaacctg ctatttttga tttttttaat
     9121 ccctctttta gggaagccta ctttaaagat gttcattatg agctagaaaa gcagggagta
     9181 gatttttggt ggattgactg gcaacaaggg acacaaggta tgctagatcc actttggctt
     9241 ttaaaccatt atcactatca ggatagttgt aaaaatgcag aaggtggttt gattttatca
     9301 agatatgcag gtcctggtag tcaccgctac cctgttggtt tttcagggga cactattatt
     9361 agttggaatt ccttaagatt tcaaccctat tttacagcga cagcatctaa tatcggttat
     9421 agttggtgga gtcatgatat cggtggacat atgttggggg attatgacga agagctacaa
     9481 actagatggc tacagtttgg tgtttttagt ccgattactc gattacatag ttctagaagt
     9541 ccttttaata gtaaagaacc ttggttcttt tcagaaacaa catctaagat tatgaagaaa
     9601 taccttcgtt tgagacatca gatgattccc tatctatata ccatgaatgt aaagacacat
     9661 gaggaaggtg ccccattaat cagtccaatc tattatttct atccagagaa tgatgagagc
     9721 tataatgttc caaaccaata cttttttgga acagaactga tggtggctcc cattgtagaa
     9781 aagatggatt tgacattcca atctgcaaaa gtagatgtat ggttccctga agatgaatgg
     9841 tatgacttct tttcagagaa aaaatacaca ggtggtgtga agttaagtgt ttatagggac
     9901 atctcgacta cgcctgtgtt tgcaaaaagt ggtgcaatca ttcccttggt tggttctgag
     9961 ataggtatgg gtgttgattt acctgaggtt gtagattggt atgtattccc agggaaacaa
    10021 cattcttttg aaatgcttga agatcaaaat ggtcaaagat ataaaacaag attatcaatc
    10081 gattgggaaa tgggaatggt agagttagca ttacaaggag attctagtat cgttccaagc
    10141 aatagaaaac atagaattca ttttaaagga acgaatgtgt ctataattga attgccaaat
    10201 aagaatgata cagctaaatt tgaatggaaa gataataaaa ggacatcttt aaatgacgaa
    10261 gtttttagac tactaaagac agcttctctt ccatatgaat taaaagatag attgttaaat
    10321 caattcatca atgcgaaaaa ctctcatgac ttaatgaata tcttgcatca tcaggataag
    10381 gaattgagag ggcgtttgtt ggaaatgata tttactagcc aaaactaatt gaaataatta
    10441 gaaagtcatt tgtttagtgt atatgaagat tctgtatggt attcgttatc actggtcaca
    10501 ttgaaaatgt gaaataagca cctacaacat agactttaca acacttcatg ttttatatca
    10561 tggggtgttt ttctatttaa gtcaaagccc atcaaaaaat ctcactattc atcaggttaa
    10621 aggaaaccta atcatagtga gattgtgaat tatagtagag tttgtatcgc ctcttcaatt
    10681 tgttttgggt ttgtttttga agaaaagcgt tcaaagactt gcccatcacg accaatgaga
    10741 aacttagcga aattccattc gattcgtttt cctagtgggc cagatttatg gtcttttaac
    10801 cagacataga gagggtctgc ttccttaccg ttgaccttaa tcttggcaaa acgtgggaag
    10861 gtggtttgaa aatgtaggct acagaaggcg ttgatttcct ctgcgctgcc gggtgcttgt
    10921 cccataaact gattgcaagg gaaatccaat atttcaaagc cctgatcttg atagcgttca
    10981 tagagttctt gaagtccctg gtactggggc gttaaaccac atccagtagc agtgttgaca
    11041 atcaagagaa ctttaccacg atagctatcc aagggagttg cttggttgtt ttggttcaaa
    11101 acggaaaaat cataaagtga agtcatgagg gcctcttttc tttttctaca ttgtaacagt
    11161 ttttactttt ttcgtcgagt cggatggaag atattgttga agaataagcc ttcaatatga
    11221 tagaaaccgt ttacaaataa ctttaaaaat ggtatgattt aattaaaccg gtttactttg
    11281 ttgctataaa tctctaattt gagatttagt tcctattgat tttacaatat gtttattgga
    11341 gtgtatacat gcaaacaaaa acaaagaagc tcattgtgag tttgtcttca cttgttttat
    11401 caggattttt attaaaccat tatatgacag ttggagcgga agaaacgact acgaatacca
    11461 ttcagcaaag ccagaaggaa gttcagtatc agcaaaggga tacaaaaaat ttagttgaaa
    11521 atggtgattt tggtcagacg gaggacggaa gcagtccgtg gacaggaagc aaagctcagg
    11581 ggtggtcaac ttgggtagac cagaagaata gttctgcaga tgcctcaact cgagtcattg
    11641 aggctaagga tggggctatc actatctcaa gccatgagaa attaagggca gcgcttcacc
    11701 gtatggttcc tattgaagct aagaaaaagt ataaactgcg tttcaagatt aaaacagatc
    11761 ataaagtcgg gattgccaaa gttcgtatca ttgaggaaag tggtaaggac aagcgattgt
    11821 ggaattctgc aacgacgtca ggaacaaagg actggcagac cattgaagca gactatagcc
    11881 cgactttaga tgttgataaa atcaagctgg agttattcta tgaaacagga actgggactg
    11941 tttcctttaa ggatattgag ctggtagagg tagcagacca gccttctgag gattctcaaa
    12001 cagataaaca gcttgaggaa aagattgatt taccaattgg aaaaaaacat gttttttctc
    12061 ttgcggacta tacttataag gtagaaaatc ctgacattgc ttcagtcaaa aatggaattt
    12121 tagaacctct taaggaaggg acaaccaatg tcattgtcag taaagatggc aaggaagtga
    12181 aaaagattcc tttgaagatt ctagcctctg ttaaggatgc atacacagac cgtttggatg
    12241 actggaatgg catcatcgct gggaatcaat actatgattc taaaaatgaa cagatggcca
    12301 aattaaacca ggaattggaa ggaaaggtag ctgatagcct atctagtatt tcaagtcagg
    12361 cggaccgcac ctatttgtgg gaaaaatttt caaattataa aatgtctgca aatctgactg
    12421 ccacttatcg gaaattggag gagatggcca agcaagtgac caatccttct tctcgttatt
    12481 atcaagatga aactgtcgtt cgaacagtca gggattccat ggaatggatg cataaacatg
    12541 tctacaatag tgaaaagagc attgttggga actggtggga ttatgaaatc ggtacacctc
    12601 gtgccatcaa caataccttg tctctgatga aagaatactt ctctgatgag gaaattaaaa
    12661 aatatacaga tgtgattgaa aaatttgtac cagatcccga acatttccga aagacgactg
    12721 ataacccatt caaggctcta ggtggaaact tagttgatat gggaagggta aaagtaatag
    12781 ctggtttact gcgtaaggat gatcaagaaa tttcttctac cattcgctcg attgagcaag
    12841 tgttcaagtt ggtagaccaa ggtgaaggtt tttatcaaga tggatcctat atcgaccaca
    12901 ccaatgttgc ctatacgggt gcttatggga atgttttgat tgatggcctg tctcaactgt
    12961 tgccagtcat tcaaaagacc aagaatccaa tcgataaaga taaaatgcaa accatgtacc
    13021 actggattga taaatcgttt gctcctttgc tggtgaatgg agagctgatg gatatgagtc
    13081 gtggacgctc gatcagtcgt gcaaatagcg aggggcacgt ggccgcagta gaagtactaa
    13141 gagggattca ccgaatagcg gatatgtctg aaggagaaac caaacaacgt ttgcagagtc
    13201 ttgtgaagac cattgttcaa tcggatagtt attatgatgt ctttaagaat ttgaagactt
    13261 ataaggatat cagtttgatg caatccttgt taagtgatgc aggagtcgca agtgttccaa
    13321 gaacaagtta cctatctgcc tttaacaaga tggataaaac agccatgtac aatgcagaga
    13381 aagggtttgg atttggcttg tcactctttt ccagccgtac cttgaattac gaacacatga
    13441 acaaggaaaa taaaagtggt tggtatacga gtgatgggat gttctatctt tacaatggcg
    13501 atttgagtca ctatagcgat ggctactggc caacagttaa tccatataag atgcctggta
    13561 caacagagac ggatgctaag agagcggata gcgatacagg taaagtttta ccgtctgctt
    13621 tcgttggaac gagcaaacta gatgatgcca atgcgacagc aaccatggat ttcaccaact
    13681 ggaatcaaac attgactgct cataagagct ggtttatgct aaaggataag attgcctttt
    13741 taggaagcaa tatccaaaac acttcaacag atactgctgc aactacaatt gaccagagaa
    13801 aactggaatc aagtaatcca tataaagtct atgtcaatga taaagaagcc tcccttacag
    13861 aacaagaaaa ggattatcct gaaacccaaa gtgtcttttt agaatcgtcc gattcgaaaa
    13921 agaatattgg ttactttttc tttaagaaga gttcaatcag tatgagtaag gctttgcaaa
    13981 agggagcctg gaaggatatc aatgaaggac agtcagacaa ggaagttgaa aatgaatttc
    14041 ttactattag tcaggctcat aagcaaaatg gagattctta tggctatatg ctcattccta
    14101 acgtggatcg tgccaccttc aatcaaatga taaaagagtt agaaagtagc ctcatcgaaa
    14161 ataacgaaac ccttcagtct gtttatgatg ctaaacaagg agtttggggc attgtgaaat
    14221 atgatgattc tgtctctact atttccaacc aattccaagt tttgaaacgt ggagtctata
    14281 ccattcgaaa agaaggggat gaatataaga ttgcctacta taatcctgaa acccaggaat
    14341 cagctccaga tcaggaagtc tttaaaaagc tagagcaagc agctcagcca caagtacaga
    14401 attcaaaaga aaaggaaaaa tctgaagaag aaaagaacca ttcggatcaa aagaatctcc
    14461 ctcagacagg agaaggtcag tcaatcttgg caagtctagg gttcttgcta cttggggcgt
    14521 tttatttatt ccgtagagga aagaacaact aatttgttca tcatctagat gaattacatg
    14581 aaactgtgga aaatagaaaa aatccgaaga aggccaaata tcttcggatt tttcttttaa
    14641 aaagggataa gttgatactt atcctttttt acttcattat gtgactatag cgttttgaaa
    14701 ctagaatagg acgtcataac tgctaaaaga tttctataaa ttcatttgat tttcctaatc
    14761 aatttgttcg tatcctattt cactccacta tattagtccg tctcgctccg tgaggtgcga
    14821 gacaaaacaa ccacccgcta tgcgggtgcg cgtcgaaggc tataccaaaa aactccaaac
    14881 gcgatacaat aaaggtgttc aatccaattg taaagcgaaa ggagaaaaaa tatggcacaa
    14941 aagactcata gtttatcata cacaaagtgg atgtgttcta tcatattgtg ttcaccccta
    15001 agtatagacg aaaagtcatc tataatcaat atagaagtag tttaggcgaa atatttcatc
    15061 gcttgtgtgg ttataaaggt gttgaaatga tcgagggtca cttaatgcca gaccatgtac
    15121 acatgttagt cagtattcca ctaaggctaa gtgtttcgag tttcatgggg tatttaaaag
    15181 gcaaaagtgc actcatgatg tttgacaaac acgccaatct caagtacaag tttgggaatc
    15241 ggcatttctg ggcggaaggt tattatgtaa gtacagtagg gcttaataaa gccacactta
    15301 agaaatatag tcaagattaa agaaattatc gagtggatga tttcttcacg agtatgaaaa
    15361 tttgagaacg agtaaagtat gatatatagt aaaatgaaat aagaacagga caaaatcgat
    15421 caggacagtc aaatcgattt ttaacaatgt tttagaagta gaggtgtact attccagttt
    15481 caatctacta tagcactaga taaattgagt gtaaaagaat atgaggatcc ctttagggat
    15541 agtggtaagt aataccaaag tctcttaaag aggcaagtga cgagtcaaga gcaataaggc
    15601 ttgaacaacg tgaaagccag cgtctttagg cgctggctgg taatttgggc ttatagctct
    15661 gggataaacc acccgtttga cgggtggtta tgattttatc tgagtgtaac atactgttgg
    15721 gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga gtttattgag ttcgccacca
    15781 attccaacgg cgtctgcacc agcagcgaac cattgaggga tgttgtttag accgactcct
    15841 ccggttacca ttacggaaac ttgtgggatc ggtgccttga ctgcagagat atatgctgga
    15901 ctgagagcac tacctgggaa gagtttgatg atttcactac cggcttcaag tgcagtcgtg
    15961 atctctgtga gggtaataca gcctggaatg tacggtgtgc tgtagagatt gcacattttc
    16021 gcagtttcag catggaaaga tggagaaaca acgtaatttg ctccggctag aatggcatct
    16081 ctagcagtta cggcatcaag cacagtacct gcaccgatac aaacactctg atcgtcctga
    16141 tacaagtcta caagttcctt gatgatttgt cctgcatact gattggtata ggcgatttca
    16201 atagctttga taccgccctt gatacaagca atcgaggctt gcagtccttc ttcctttgta
    16261 tttcctcgaa tgacagcgac aattttctgt ttttttagtt caataatcgt atctgatttg
    16321 gtcatgtaat tctcctaacg aatgatatct tgtgcatttg ccagtaaatt ttcaatacta
    16381 gttgcggaag tggagagatg gtctcctgga agagtgcatt tgagagttgc gctcgcaact
    16441 gcaaagtcaa tggtagtttt tagggaggaa tgatggagta gttggtaaag ggcaccagat
    16501 ataaaggcat ccccgctacc aattcgttga tagactgcag tttttagttg gacagactct
    16561 tcaaatcgtt cttccagagc ataggcttga tagacatttt tgtcttgctc atcactagag
    16621 cggagggtat ggaaaatggc cttgaaacca taggcttctt ttaaaagtcg catgcgattt
    16681 tccacctctt ctaggctagc actgtctctt ggaaacatct ctagattttg gtcatcaatc
    16741 atgagaggat caataccgaa gcaatagtca gtaaaacgtg caaacttaga aaattcatac
    16801 ttggcttcta ggactgaaat catctttgtt ctcagattga gatccattga aacgacaatt
    16861 cctcggcgct tggcttcttc caagagtagg agaaggatcg cacggacctc ttgaccgata
    16921 gctacggtga ttccactaaa atgaaaatgg ctaatcccct gaaagagaga atccatatct
    16981 agcatgtttg gccgaatctg gctgatactc gtatgcttac gatcgtagaa aacttcactt
    17041 tgacgacaac caaagccgtt ctccaaatag tagaggccga ttcgatcgcc aagccgacag
    17101 attgaactgg tatcgatttg gtgctgtttc aagaatgtga gaaaacgatc tccaatctcg
    17161 ttggcaggga gtgcggtaaa gactttcgtt gagataccca gggcttgcaa attacaagcg
    17221 atgttaattt ctgatccgcc aaaataagtc gaactggcaa catgatcgcc gatactggtg
    17281 gcatctaatg gtgagattcg aattaatggt tcgccaaaca gtaatatttt cgtcatccat
    17341 tagttccttt ctggtttaga atagctttac ttggctaata cttctttcaa ataagcagcg
    17401 acttcatcat cttggcagtt ttcaaagaag tattcttgga aatatttgcc agagatggtg
    17461 tctttgagga agtcttggtc gattgtttta aggatggtca tcaaatcatt gtgggtgatt
    17521 tgtttcacct cgtttaagat acgagcgttg cgttgttcag ggattacacg ttctcttggg
    17581 tagccaccgc ccatttcttc agcaaataag cgttcaaaca tcaatttgag ggtcagttct
    17641 gccccccagc caaatccttt ggcataaggg atagacaagg cgttaccacc attgatttga
    17701 gaataaaggt aagcgtcagt tgggtccact gctagaccac agacaacacc agggaagctg
    17761 tttaaagcaa gcatagcccc tacacccgta ccacagccgg taacaacaaa gtcaactgcc
    17821 tttgtattta aaaggatggc agccattagt ccgttctgca cataagttaa ttgactttct
    17881 ccttcttctc cacgcatacc atagttaaat aattggtagc cttttttatc tgtcgcttct
    17941 tttagactat cgtaaataat gtgattcttg ctagcttgac tattttcatt gattaatgcg
    18001 attttcataa gatcttcttt ctatttttac tcaggttgtt ttccgatgta ggctaagata
    18061 ccgccatcta catataggat gtggccattg acaaaattgc tggcatcact agcgagaaag
    18121 acagcagggc ccatcaaatc ttcaggattt ccccaacgtg cagcaggtgt ttttgcaatg
    18181 atgaactggt caaatgggtg gcgagaacca tcttcttgca actcacgaag aggtgctgtt
    18241 tgaggagtgg caatataacc cggtccaatt ccgttacatt ggatattggc tccaccgtat
    18301 tcagacgcaa tgttgcgggt caacattttc aagccccctt tagcagcagc ataagcgcta
    18361 actgtttcac gtcccagttc gctcatcatc gaacaaatat tgataatctt tccatgccct
    18421 ttctttatca tagaaggaat aactgccttt gaaacgataa atggtgcgtt taagtcaata
    18481 tcgatgacct tacggaaatc agcggcgctc atttcgcaca ttggaactcg gcggataata
    18541 ccagcgttat taacgaggat gtcaatgaca ccaacctctt gttcgatttg cttgaccatg
    18601 gcttggatac cgtcctcgtc tgtcacgtca cagacatatc catgggcttc gatgccaact
    18661 tcacgataag cttcaatccc tttattgacc agatcttgat tgatatcgtt aaagacaata
    18721 gtagcgccgg cttcagcgta ggatttggca atagcaaatc caattccata agaagcgccg
    18781 gtgatgagag caatttttcc ttttaaagaa aactgctcaa ttgagaatga tgtatttgtc
    18841 atttgatact tcctttcaaa tttgttaaga cttctctata accaaattat attctagtaa
    18901 accggttttg tcaataaata aatattttta tttataaaaa gatttatttt cc
//
LOCUS       DBERAE010000043        17980 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.43, whole genome shotgun sequence.
ACCESSION   DBERAE010000043 DBERAE010000000
VERSION     DBERAE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.43"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..508
                     /locus_tag="ACL70N_001723"
     CDS             <1..508
                     /locus_tag="ACL70N_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HGS0590483.1"
                     /translation="RKSNKETSKVRPYFIGGHPGFNCPLLDDEVYEDYYLEFEKEETC
                     SVPRPFPETGMLDFQDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDK
                     GLKVHFAEFPNLIIWSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEE
                     LGFEIEVL"
     gene            665..1090
                     /gene="lacA"
                     /locus_tag="ACL70N_001724"
     CDS             665..1090
                     /gene="lacA"
                     /locus_tag="ACL70N_001724"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGS0590484.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1121..1636
                     /gene="lacB"
                     /locus_tag="ACL70N_001725"
     CDS             1121..1636
                     /gene="lacB"
                     /locus_tag="ACL70N_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGS0590485.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1647..2576
                     /locus_tag="ACL70N_001726"
     CDS             1647..2576
                     /locus_tag="ACL70N_001726"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGS0590486.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2578..3558
                     /gene="lacD"
                     /locus_tag="ACL70N_001727"
     CDS             2578..3558
                     /gene="lacD"
                     /locus_tag="ACL70N_001727"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGS0590487.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3964..4440
                     /locus_tag="ACL70N_001728"
     CDS             3964..4440
                     /locus_tag="ACL70N_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590488.1"
                     /translation="MNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEE
                     LAKNIGISVQEASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAG
                     WHLKQFAVNPVTSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            4838..5674
                     /locus_tag="ACL70N_001729"
     CDS             4838..5674
                     /locus_tag="ACL70N_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS0590489.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5710..6027
                     /locus_tag="ACL70N_001730"
     CDS             5710..6027
                     /locus_tag="ACL70N_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0590490.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6027..7718
                     /locus_tag="ACL70N_001731"
     CDS             6027..7718
                     /locus_tag="ACL70N_001731"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS0590491.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            7927..9333
                     /gene="lacG"
                     /locus_tag="ACL70N_001732"
     CDS             7927..9333
                     /gene="lacG"
                     /locus_tag="ACL70N_001732"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS0590492.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9376..9633
                     /locus_tag="ACL70N_001733"
     CDS             9376..9633
                     /locus_tag="ACL70N_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGS0590493.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEGWDTISFDSDFMPFQQS"
     gene            complement(9912..10673)
                     /locus_tag="ACL70N_001734"
     CDS             complement(9912..10673)
                     /locus_tag="ACL70N_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0590494.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10855..11817)
                     /gene="nrdF"
                     /locus_tag="ACL70N_001735"
     CDS             complement(10855..11817)
                     /gene="nrdF"
                     /locus_tag="ACL70N_001735"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGS0590495.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12005..14164)
                     /gene="nrdE"
                     /locus_tag="ACL70N_001736"
     CDS             complement(12005..14164)
                     /gene="nrdE"
                     /locus_tag="ACL70N_001736"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGS0590496.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14245..14463)
                     /gene="nrdH"
                     /locus_tag="ACL70N_001737"
     CDS             complement(14245..14463)
                     /gene="nrdH"
                     /locus_tag="ACL70N_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGS0590497.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            14814..15077
                     /locus_tag="ACL70N_001738"
     CDS             14814..15077
                     /locus_tag="ACL70N_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGS0590498.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            15083..16816
                     /gene="ptsP"
                     /locus_tag="ACL70N_001739"
     CDS             15083..16816
                     /gene="ptsP"
                     /locus_tag="ACL70N_001739"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGS0590499.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            17070..>17980
                     /gene="phtA"
                     /locus_tag="ACL70N_001740"
     CDS             17070..>17980
                     /gene="phtA"
                     /locus_tag="ACL70N_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGS0590500.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHV"
BASE COUNT         5627 a         3207 c         3732 g         5414 t
ORIGIN      
        1 caggaagtct aataaagaaa ctagcaaggt caggccttac tttattggtg gacatccagg
       61 atttaattgt cctctacttg atgatgaagt ctatgaagat tattatctag agtttgagaa
      121 agaagagact tgctctgttc cacgtccttt cccagaaaca ggtatgttgg atttccaaga
      181 tagaagtcca tggctagagg gacaaaaaga aatagatctt agttatgatc ttttcagcac
      241 agatgcagtg actttggatg aattgcaatc tcgaacaatt gcccttcgtt ctcttaaaca
      301 tgataaggga ttgaaagtgc attttgcaga atttccaaac ctcatcatct ggtcaacttt
      361 gaacaaggga cctttcatta cctttgaacc atggtctggc ttgtcaacat cccttgaaga
      421 aggagatcat ttagaagata agaagaatgt ttgtctctta gaagccaatc aggttgaaga
      481 attagggttt gagatagaag ttttataaaa aagtaaaaaa taaataacaa aaacaaacac
      541 aaactattga cttcttcaaa caatagtagt atattatgtt tgtgaggact aattgactgt
      601 tttttaaaga tagccaatac actgctggaa tccagcatag aaaaaataaa aaggagtata
      661 caatatgtct attgttatcg gtgcagatgc tgcaggtttg agattgaaag aagttgtgaa
      721 agacttctta gaaaaagaaa acttccacct tgtggatgtt acagctgaag gtcaagactt
      781 tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa gaagaacaaa accttggtat
      841 cgtgattgat gcttatggag ctggtccatt tatggttgca actaagatca aaggaatggt
      901 tgctgcagaa gtatctgacg aacgttcagc ttatatgact cgtggccaca acaactcacg
      961 tatgatcact atgggggcac aacttgttgg tgatgaattg gctaaaaaca tcgctaaagg
     1021 atttgttaat ggtaaatacg acggtggtcg tcaccaaatc cgggttgaca tgttgaacaa
     1081 aatgggctaa ttagattata gtaagaaagg taagttaaaa atgagaattg caattggatg
     1141 tgaccacatc gtaactgatg aaaaaatggc ggtttcagaa tttttgaaat caaaaggata
     1201 tgaagtcatt gactttggta catatgacca tacacggact cactacccaa tctttggtaa
     1261 aaaagtaggg gaagcagtaa ctagtggtca agctgatctt ggggtatgta tctgtggtac
     1321 tggtgttggt atcaacaacg ctgtaaataa agttccaggt gttcgttctg ccttggttcg
     1381 tgatatgaca acagcccttt atgctaaaga acaattgaac gctaacgtta tcggctttgg
     1441 tggtaagatt actggtgaat tgcttatgtg tgatatcatc gaagctttca ttcatgctga
     1501 atacaaacca tctgaagaaa acaagaaatt gattgcgaaa attgaacacc ttgaaagtca
     1561 caatgctcaa caaacagacg caaacttctt tacagaattc cttgaaaaat gggatcgcgg
     1621 agaataccac gactaagagg tgacctatga ttttaacagt cacaatgaac ccatccattg
     1681 atatttccta tcccttggat gagttgaaga ttgatactgt caatcgtgtg gtggatgtaa
     1741 ccaaaacggc tggtggtaag ggacttaatg ttacccgagt actttcagaa tttggcgatt
     1801 ctgttcttgc tactggttta gtgggtggca aacttggtga gtttttggtt gaacatatcg
     1861 ataatcaagt aaagaaagat ttcttctcaa ttcagggaga aactcgtaac tgtatcgcta
     1921 ttctccacgg agacaaccaa acagaagttc ttgaaaaagg tcctgaagta ttggaacagg
     1981 aaggtcaaga ctttttggaa catttcaaaa aactcttgga gtcagttgaa gtagtggcca
     2041 tctcaggtag tctgccagct ggccttccag ttgattacta tgcgagcttg gtagaacttg
     2101 ctaatcaagc tggcaagcct gtagtcttgg actgctcagg tgcagcactt caggctgttc
     2161 ttgaatcacc ccataaacca acagtcatca aaccaaataa tgaagaattg tctcagcttc
     2221 ttggaagaga agtttctgag gatttggatg aattaaaaga agtacttcaa gaacctttgt
     2281 ttgcagggat tgaatggatt atcgtttcac ttggtgccaa cggtactttt gccaaacatg
     2341 gtgacacttt ctacaaggta gatattccta gaattcaggt ggtaaatcct gttggatctg
     2401 gagactctac tgtggcagga atttcttcag gacttcttca caaagaatcg gatgcagaat
     2461 tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca agaaaaaatg actggtcatg
     2521 tcaacatggc caactatcaa gctctatatg atcaattaat agtaaaagag gtataaaatg
     2581 gctttaacag aacaaaaacg tgtacgctta gaaaaacttt ctgatgaaaa tggtatcatc
     2641 tcagctcttg catttgacca acgtggtgct ttgaaacgcc tcatggctca acaccaaaca
     2701 gaagaaccaa ctgtggccca aatggaagaa cttaaagtct tggtagcaga tgaattgact
     2761 aaatacgctt catctatgct tcttgaccct gagtatggac ttccagcaac taaagctctt
     2821 gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag gttatgacac aacaagcaca
     2881 aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac gtattaaaga agaaggtgca
     2941 gatgcagtta aattcttgct ttactatgat gtagatagct cagacgaact caatcaagaa
     3001 aaacaagcct acatcgaacg catcggttct gagtgtgtgg ctgaagatat cccattcttc
     3061 cttgaaatcc ttgcttacga tgaaaaaatt gcggatgcag gttctgtaga atacgctaaa
     3121 gtaaaaccac acaaagttat cggcgctatg aaagtctttt cagacccacg ctttaacatt
     3181 gatgttttga aagttgaagt tcctgttaac attaaatatg ttgaaggctt cgctgaaggt
     3241 gaagtagttt atacacgtga agaagcagca gccttcttca aagcgcaaga tgaagcaacg
     3301 aacttgccat acatctactt gagtgctggt gtatcagcta aactcttcca agatactctt
     3361 gtatttgctc atgaatcagg tgcaaacttt aacggagttc tttgtggccg tgctacatgg
     3421 gcaggatcag ttgaagctta catcaaagat ggtgaagcag cagctcgcga atggcttcgc
     3481 acaactggat ttgaaaacat tgacgaactc aacaaagttc ttcaaagaac agcaacttca
     3541 tggaaagaac gcgtgtaaga aagtcctcct agtttaggaa catgaatcta aaaaaattta
     3601 aaaaaagttg tatgtaaagg tttacaaaat aacttacttg tgctatactt aaatcacaag
     3661 ttaatatgaa ttagaaagta actatatgaa gtataataaa aataggatat agtttatttt
     3721 acgagctagg aaggaaaaat acggaaacaa tattgccaga ataaactata tttagatgca
     3781 catttcattc attgttttat aaaaggagaa gataaacggc tactaaaaag agttttaaag
     3841 cgttagttgt aggactaggt attgtttcaa tattctcatc agccttacct atggttagtg
     3901 gttctgtatt tgcagatagt gccctaacta cagtatacag tagataaagc aaatgatatt
     3961 gttttgaatg ttgatgggaa taaattttat aatgtttcgg tttcagaaga tattgtaaat
     4021 gctggtcaaa ttttggaaga ttatttttat gtagataaat ttggaaatat aaatttaaaa
     4081 ggcactcctg aagagttagc aaaaaatatt ggtatttctg tacaagaagc aagtttgatg
     4141 tatgaagctg taaaagagtt acccaacgtt tacgaaagag gtcctgtagg ttttcgtttc
     4201 aatcttggtc ctcaagtgag ggggatgggt ggctgggctg ctggagcttt cgctactgga
     4261 tatgctggat ggcatttgaa acaatttgcg gttaatcctg ttacatctgg atttgttgct
     4321 gtaataagtg gtgcgattgg ctgggctgta aaaactgctg tagaaaatta ttggacagtt
     4381 gctgtagcta cagtagaagt gccgtttgtg aaccttgttt acaccataga tttaccttag
     4441 aggttatttc tttatgaatc attcttttaa aaaaataact gtattttgtt ttatagtttc
     4501 ttgtgttctt tgtttattag acttaatgaa ttttaaaaat gtagctactt ttttattttt
     4561 ctgtcttcct gtttttgttt tgatttacaa aaataaataa aaacagagcc tctgtttgat
     4621 gaattttaga acatagttaa gttttaaaaa aagttgtatg taaaggttta caaaacaacc
     4681 gacttgtgct atacttaaat cacaagttaa tacaaggtga gtgttactaa gtaatattag
     4741 gcatgatcac aggtgaatta gaaatcagct gattttctag ttcatttgtg gtcatttttt
     4801 gtactcatat acctttaaga tataaaagga ggttgacatg tatcgaattc taaatccaat
     4861 gaatcacaat gtctcgcttg tcagaaatga taagggagaa gaggtgatta taattggtaa
     4921 ggggattgca ttcggaaaaa ggaaggggga tttgattgct gaaaatcagg ttgagaaaat
     4981 ctttcggatg aagaccgaag agtccagaga aaactttatg gctcttctca aagatgttcc
     5041 gcttgatttt atcacagtga cctatgaaat cattgataag ctatcaaaga aatatcatta
     5101 tccgattcaa gagtatctct atgtaacctt gacagatcat atttactgtt cttatcaagc
     5161 tctaactcaa ggaaggtaca aggatagtaa tctgccggat atttccgcta agtatcctgt
     5221 cgcttttcaa atcgcaaatg aagcttttga aatttaccgt cagaagctag cagatcattt
     5281 tcctgaggac gagattattc ggattgctta tcatttcatc aatgccgaag gtgaaaatga
     5341 agtggaactt gtggagtcga ttgataagag gaaagaaatt ctcaggaatg ttgaagaagt
     5401 gctaaagggt tatgcaattc aacgaaccaa aaaaaataat catttctatg atcgctttat
     5461 gattcatttg aattatttct tggattattt agacagatct agagatgata accaatcact
     5521 tctggatatg gaagatcata ttaaacaatc ctatccaaaa gccttcgaga ttggttccaa
     5581 gatctatgat gtgattacgc aacatacggg tcttgatttg tataaaagtg aacgagttta
     5641 tctagttcta catatccaac gtttattgtc ataaaaattt atttaaaact atataaggag
     5701 aattctatca tgaatagaga agaagtaaca ttgttaggtt ttgaaatcgt agcctatgct
     5761 ggcgatgctc gttcaaaact attggaagcc ttgaaggctg ctgaagctgg tgattttgaa
     5821 aaagcggacg ctctggtaga ggaagctggt agctgtattg cagaggctca ccacgcgcaa
     5881 acaagtctat tgactaagga agcttctggt gaggacttag cgtatagtgt gaccatgatg
     5941 catggccaag accacttgat gacaactatc ttgttaaagg atttgatgca ccatttgatc
     6001 gaactctata agagaggagt taaataatga acaaactaat tgcatttatc gagaaaggaa
     6061 agcctttctt tgagaaacta tctcgtaata tctatcttcg tgctattcgt gatggtttca
     6121 ttgcaggtat gcctgttatt ctcttctcaa gtatctttat cttgattgcc tttgtaccaa
     6181 actcatgggg ctttaaatgg tctgatgaag ttgtagcctt tctgatgaaa ccttatagct
     6241 attctatggg tattctggct ctcttggtag ctggtacaac agctaagtca ttgactgact
     6301 cagtaaaccg gagcatggaa aaaaccaatc aaatcaacta tatgtcaacg ctgttagcag
     6361 cgattgttgg tttgttgatg ttggcagctg atcctatcga aagtggtcta gctactggat
     6421 tcttggggac aaaaggtttg ctttcagcct tccttgctgc cttcgttact gtagccatct
     6481 ataaggtttg tgttaagaac aacgtcacta ttcgtatgcc tgacgaagtt ccaccaaata
     6541 tctcacaagt ctttaaagat gtgattccat tcactctatc agtggtttct ctttatgctc
     6601 ttgatttact agctcgtcat tttgttggtt ctagtgtggc agaatcaatc ggtaaattct
     6661 tcgcaccact cttctcagca gcagacggat accttggtat taccattatc tttggtgcct
     6721 ttgccttctt ctggtttgtg ggtattcatg gtccatctat tgttgaacct gctatcgcag
     6781 cgattaccta tgcaaatgct gaagtcaact tgaaccttct ccaacaaggt atgcatgctg
     6841 ataaaatcct tacttcagga actcaaatgt ttatcgttac tatgggaggt actggtgcga
     6901 cactggttgt tccattcatg ttcatgtggt taacaaaatc aaaacgtaac cgtgcaatcg
     6961 gacgtgcttc agtagttcca actttctttg gtgtaaatga accaatcttg tttggtgcac
     7021 cacttgtatt aaatccaatc ttcttcattc catttatctt tgctccaatc gcaaacgtat
     7081 ggattttcaa attctttatt gaaactcttg gaatgaactc attcactgct aatctaccat
     7141 ggacaactcc agctccacta ggtctagttc ttggaactaa cttccaagtg ctatcattca
     7201 ttcttgctgc ccttctaatc gtggttgacg ttgtcattta ctatccattc cttaaggtct
     7261 atgatgaaca aattcttgaa gaagaacgtt caggtaagtc taatgatgaa ttgaaagaaa
     7321 aagttgctgc aaacttcaac actgcaaaag cggatgctat tcttgaaaaa gcgggtgtag
     7381 aagcagcaca aaatacaatc actaaagaaa caaatgtcct cgttctctgt gcaggtggag
     7441 gaacaagtgg tctccttgca aatgctttga ataaggcagc agcagaatac aatgtccctg
     7501 tgaaagcagc agcaggcggc tatggtgctc accgtgaaat gttaccagag tttgatcttg
     7561 ttatccttgc ccctcaagtt gcttcaaact ttgaagatat gaaggcagaa acagataagc
     7621 tcggtattaa actagcgaaa acagaaggcg ctcaatacat caaattaact cgtgatggaa
     7681 aaggtgctct tgcattcgta caagcgcaat tcgattaagg ctagagactc tgaaatagtc
     7741 tcctatcgtt acggaaatcg ctatggcgaa tttcctatta ttaattcgtc ggtaaaaaga
     7801 tatcgttttt acctcctcat gtcacaattc ggtgacttgg tacaagaagt gagatggaga
     7861 aggatggctc actgactcct ctcctctcac ttttacttta tttaaatcaa gaaataggtg
     7921 aaaaaaatga caaaaacact tccaaaagac tttatttttg gtggcgcaac agctgcctat
     7981 caagcagaag gtgctacaca tactgatggt aaaggaccag tagcgtggga taaatatctt
     8041 gaagataact actggtacac tgcagaacca gccagtgatt tttacaatcg atatccagtt
     8101 gacctcaagc tagcagaaga gtatggtgtc aatggtattc gaatttctat tgcttggtca
     8161 cgtattttcc cgactgatta cggccaagta aatgctaaag gtgttgagtt ttatcataat
     8221 ttatttgcag agtgtcacaa acgtcatgtt gagccttttg taactcttca tcactttgac
     8281 acgccagaag ctctccactc aaatggagac ttcttaaacc gtgaaaatat cgaacatttt
     8341 gtagactacg ctgccttctg ttttgaagaa tttccagaag taaactattg gacaaccttt
     8401 aatgaaattg gaccaatcgg tgatggtcaa tatttggttg ggaaattccc tccaggtatc
     8461 cagtacgacc ttgccaaagt ctttcaatca caccacaata tgatggtgtc tcatgcacgc
     8521 gcggtaaaat tgtacaaaga gaaaggctat aaaggggaaa ttggtgttgt tcacgccctg
     8581 ccaactaaat atcctctaga tcctgaaaat ccagcagatg ttcgtgcagc tgagttggaa
     8641 gatatcatcc acaataaatt catcttagac gcaacttatc taggtcgcta ttcagctgaa
     8701 accatggaag gtgtcaacca tatcttatca gtcaatggtg gtagcttgga tcttcgtgaa
     8761 gaagatttta cagcattaga agctgcaaaa gacttgaatg atttcctagg aatcaactac
     8821 tatatgagtg actggatgga agcctttgat ggagaaactg aaattatcca taatggtaaa
     8881 ggtgaaaaag gaagctctaa gtatcaaatc aaaggtgttg gtcgtcgtgt agctcctgac
     8941 tatgtaccac gcacggattg ggattggatt atctaccctc aaggtttgta tgaccaaatc
     9001 atgcgtgtga agaaagatta tcctaactac aagaagattt acatcactga aaatggtctc
     9061 ggctataaag atgagttcgt tgataacact gtttacgatg atggtcgtat tgattacgtg
     9121 aaacaacact tggagatctt gtctgatgcg attgcagatg gagctaatgt aaaaggttac
     9181 ttcatttggt cattaatgga tgtcttctca tggtcaaacg gttatgagaa acgttatggt
     9241 ctcttctacg tagattttga aactcaagaa cgttatccta agaaatcagc tcactggtac
     9301 aagaaagtag cggaaactca gattatagac tagtagaatt agtcattaga tatagaattt
     9361 tagtgagtca aaaagatgtt caaagatttt atccaatcta tttatgaaaa agtttatatt
     9421 ataaatttcg aaaaatgctc tcaaataccg tgtttgacga gtgaagaatt gaaaagtctt
     9481 ggaaaatggt atgtctcgac tggtaaagaa tggatttgtc attcagatga tgagctggaa
     9541 gaatttaaaa atctattttt aaattttatc aatcctgaag gatgggatac tatctccttt
     9601 gattcagatt ttatgccgtt tcaacaatcg taaccaattt ctcaaaaaag ttaaatctta
     9661 tatttagtac tctgtaaaac tcttatctaa tcacgttgct tatactcaat gaaaatcaaa
     9721 gagcaacttt aaactaggaa gcgagtcgca gatttctcaa tgcatagctt tgaggaattg
     9781 ggcaaaaagt ctttgatata gaaaaacgca tagtatcagg tgttgaaaca cctgatacta
     9841 tgcgttttat tgtgggaaga tttacttttt ttcttctgaa attgagttgt tacccaggct
     9901 ctttcagttt attaaggctt gatgacttta atgtgtttag atagcttaaa aaggattgaa
     9961 tcacttagtt tagaatctga aacaatagta tcaagatttg atacattata aaaagtataa
    10021 aaatcaaact tattgaactt gctatgatct gcgagtaaat attttttatt agaattattt
    10081 aaagcgatgc gttgagcctc tccctcttcc tcgctaaaag tagctagagc tccgttttga
    10141 ataccattac agctaacgaa agctttagaa aattggagat tagagagatt ttgtagggtc
    10201 aatgtaccaa caaaagcacc tgtaatatcg cgataatttc cacctattaa aatcaaatct
    10261 gttaattttc gttcgcttaa aatcagaaaa acaggtagac tgttggttac gacgcggata
    10321 ttgtcaatag gcaactcacg cgcaaaaaac tctaatgttg ttcctggtcc aatgaaaata
    10381 gtttctcttt cttctactag actgcctgca aaatgggcta tttcttgttt ttctgccgtt
    10441 tggagggctt gtttttcaat atttgatcgc tcattagtca aaagggagtt ggttcgaagt
    10501 ttttcagctc caccatgcac acgaatcagc aaatctttat cagctaattc ctgtaaatag
    10561 cgccttgcag tcatatctga aacggctatt tcgtccataa tctgtttaac tgttatggtt
    10621 cctttactat ttactatctc taaaattttg gctaattttt cttgtttgag catattatca
    10681 cctcgtttcc tactactatc ttaccataaa caaactcatc attcaaatac aaaaacaaca
    10741 aaatgaaaca aaaacaaaaa tatcgaagtt tgttttcaaa actttcgata tttttgttgg
    10801 gttataactt tgatgtttct agtttacttt ttgatgattg agagtgatgg agaattagtc
    10861 taaaccgtag ttatagtcat cgtcttgcat ggcttcaact tcgccaagaa ggtaaccatt
    10921 tccgacttga gagaagaagt catggttgga agttcctgtt gaaataccgt tcataacgat
    10981 tgggttgaca tcttcagctg aatctgggaa aagtggatct tgtcccatgt tcatgagagc
    11041 tttattggca ttgtagcgaa ggaaggtttt aacctcttca gtccaaccaa caccgtcata
    11101 aagactctct gtgtagcctt cttcattttc ataaagagta tagagtaggt cgtacatcca
    11161 ttctttgagt ttttcttgct cttcttcagg caattcattg aaaccaagtt ggaatttgta
    11221 accaatgtag gttccgtgaa cagactcgtc acgaataatc aatttaatga tttctgcaac
    11281 gttggcaagt ttgttgttac cgagatagta gaggggagtg aagaaaccag agtagaagag
    11341 gaaggtttcg aggaagacgc tggcaacttt cttttcaagt gggctgccgt ttaggtagat
    11401 ttcgttgaca atctcagcct tcttttgtag gtaaggattg gtattggtcc attcgaaaat
    11461 ttcttcaatc tcagccttag tattcaaggt agaaaagatt gatgagtaag atttagcgtg
    11521 gacagattcc ataaattgga tgttattgaa aacagcttcc tcatgtggtg tacggatgtc
    11581 tgcgcgaagg gcttgaaccc cagtttcaga ttgcatagtg tcaagaaggg ttaaaccacc
    11641 aaaaactttt ccgaccaagt ctttctcttt gttagatagc tttctccagt catccaagtc
    11701 gtttgataag ggaatacgtg tatcgagcca aaattgctcc gtcagttttt cccaagttga
    11761 tttgtcgatg acatcttcga tggcattcca gttaatggct ttgtagtaag tttccattta
    11821 aaatctcttt ctgtgtttag tattgcgaac tcacaattat ttctacttta ccataattct
    11881 ataggagtat cgcacaaaaa gtcggaagcc cgacttttaa aatgttacat aaattatgtt
    11941 atgacatagt agatttgatt ttatcagtgc tgcttaggga aaaatagtgt ttctatgcta
    12001 gaaactaaat cacacagctt tcacattggt tggcgccgac ttctccaccg tcatctgtaa
    12061 aggtacggac gtagtagata gacttgattc ccttgttaaa ggcatagtta cgaaggatgg
    12121 acaaatcacg tgtcgtttgt ttattttccc tcttccattc gtaaaggcct tttggaatgt
    12181 cactacgcat gaagagggtg agtgaaagtc cttgatccac gtgttcagtc gcagcagcgt
    12241 aaacatcgat gactttacgc atatccatat cgtaggcaga agtgtagtaa ggaatggttt
    12301 ctgtagacaa gccagcagca gggtagtaga ttttaccaat tttcttctct tggcgttctt
    12361 cgatacgttg cgtaatcggg tggatagaag cagaaacgtc gttgatatag ctgatagaac
    12421 catttggcgc tacagcaagg cgattttggt ggtaaagacc atcttcttga accttgtcgc
    12481 gaagttcagc ccaatcagca acaccaggga taaagacatt tttgaagagt tctttaacac
    12541 ggtctgatgt tggaacaaat tcaccagtta catacttgtc aaagtaactt ccgttagcat
    12601 agtctgattt ttcaaagttg tggaaggtaa taccacgttc acgcgcaata ttgtttgact
    12661 ctaccaaggt ccagtagttc ataagcataa agtagatgct tgtaaattca acagactcag
    12721 gtgaaccata ttcaatgagt tgttgggcaa ggtagctgtg cagtcccatg gcaccgagac
    12781 caaaggtgtg ggcttggcta tttccatggt caatcgttgg tacagctacg atatgtgaac
    12841 tatctgtaac gaaagtaagg gcacgaacca tagcacggat agaacgacca aaatcaggtg
    12901 aagtcatcat gttaaccacg ttggttgaac ccaggttaca tgaaacatct gttcccattt
    12961 gaaggaattc ttgagcatcg ttgatcaagc ttggttcttg aacttgaaga atctcagaac
    13021 acaagttact catgataatc tttccatcaa caggatttgc acggttagcc gtatcgatgt
    13081 tgactacata aggatagcca gactcttgtt gcaatttaga gatttcagtt tccaaatccc
    13141 gcgccttgat ttttgtcttg cgaatatttg gatttgcgac caattcatcg tatttttcag
    13201 taatgtcgat gtaattgaat ggcacaccgt attctttttc tacagagtaa gggctgaaga
    13261 ggtacatttc ttcattttta cgagccaatt cgtagaattt atcaggtact acaacaccaa
    13321 gtgatagagt cttgacacgt actttttcat cagcgttttc tttcttagtt gaaaggaaag
    13381 cgatgatatc tgggtgaaag acgttgaggt agacaacacc ggcaccttga cgttgcccca
    13441 attggttgga gtaagagaag ctgtcttcaa aaagcttcat aacaggaacg acacctgaag
    13501 cagctccttc atagcctttg ataggtgcac cagcttcacg aaggttgctg agggtaattc
    13561 ccacaccacc accaatacgt gaaagttgaa gagctgagtt gatagaacgt ccgatagagt
    13621 tcatatcatc cgtcacttgg attaggaaac aagataccaa ctccccacgg cgagcacgtc
    13681 cagcattcaa gaaggaagga gtagcaggtt ggtagcgttg gtggatgatt tcattggcaa
    13741 tatcgattgc aacagcttca ttcccatcag cgaaataaag ggcgttgaag aagacacggt
    13801 cttccatatt ttcaagatag tattcaccgt cattagtctt taaggcatat tgattgtaaa
    13861 atttataagc tgccatgaat gacttgaatt ggaagttttg gtctttgata aattgagcca
    13921 attcttccaa gaactctgga cggtatttct tgataaaggc tgtttcgatg tagttgtgtt
    13981 caatgaggta attgattttg tctttgattg aatcaaaaac catagtgttt ggaactacat
    14041 tttctttaaa gaaagcatcc aaggcttcct tgtctttatg aagcatgatt tgtccattaa
    14101 caggacggtt aatttcgtta ttaagacgga agtaagtcac gtcttcaaga tgttttaatc
    14161 ccataaaatt tcccttatct aattacaaaa gaaaggcttc taagttagcc ctaaaagcag
    14221 ttttttctgg atgatgtact aagattatgc taattgcttc agttttcctg gttggaaacc
    14281 tgaaaagact tcagttggtg tttggataac aggagctgcg ctaaaaccga gctctttaac
    14341 ttgatcgacg tactcaggtt gctcatcaag attgatttca cgataagaga cattattact
    14401 gtccaagaaa cgcttggtca ttttacattg gacacaattg tttttagaat aaacggttac
    14461 cattgtgtaa ctcctcttca aaatttaata ctatcttagt atatcagaaa ataaaatttt
    14521 gtcaatgatt tgaactaaat atagtggtgt tcttttgttg tttttatata taaacacaat
    14581 atatagtgtt tgtgttgtga aatagcaatg attatcctat aaattgtttt tgaagaaact
    14641 atatcctgtg ttttgttatc taggatagaa gattttcagc aagttatctg aaaggaaatt
    14701 gaaggaaaat ccagaaaatg cttgaaaaaa atcctagaag atggtataat actaaattgt
    14761 aagggttatc acatataact caaaaaaaga aagaacaaaa ggagagtcaa actatggctt
    14821 ctaaagattt ccacgtagtg gcagaaacag gtattcacgc acgtccagca acattgttgg
    14881 tacaaactgc tagcaaattt gcttcagata tcactcttga gtacaaaggt aaatcagtta
    14941 accttaaatc aattatgggt gttatgagtc ttggtgttgg ccaaggtgct gacgtaacta
    15001 tctcagctga aggtgcagat gcagatgacg ctatcgctgc aatctcagaa acaatggaaa
    15061 aagaaggatt ggcataaggg aaatgacaga aatgcttaaa ggaatcgcag catctgacgg
    15121 tgttgcagtt gcaaaagcat atctactcgt tcagccggat ttgtcatttg agactattac
    15181 agtcgaagat acaaacgcag aagaagctcg ccttgatgcc gctctacagg catcacaaga
    15241 cgagctttct gttattcgcg agaaagcagt aggtacgctc ggtgaagaag cagctcaagt
    15301 ttttgatgct cacttaatgg ttcttgctga cccagaaatg atcagccaaa tcaaggaaac
    15361 tatccgtgcg aagaaagtga atgcagaagc aggtctgaaa gaagttacag atatgtttat
    15421 cactatcttt gaaggcatgg aagacaaccc atacatgcaa gaacgcgcag cggatatccg
    15481 cgacgtgaca aaacgtgtat tggcaaacct tcttggtaaa aaattgccaa acccagcttc
    15541 tatcaatgaa gaagtgattg tgattgcgca tgacttgact ccttcagata cagctcaatt
    15601 ggacaaaaac tttgtaaaag cttttgtaac caacattggt ggacgtacaa gccactcagc
    15661 tatcatggca cgtacacttg aaattgctgc tgtattaggt acaaacaaca tcactgaaat
    15721 cgttaaagac ggtgacatcc ttgctgttaa cgggatcact ggagaagtga ttatcaaccc
    15781 aacagatgaa caagcggcag aatttaaagc agctggtgaa gcctatgcga aacaaaaagc
    15841 tgaatgggca cttttgaaag atgctcaaac agtgactgct gacggtaaac acttcgagtt
    15901 ggctgccaat attggtactc caaaagacgt tgaaggtgtt aacaacaacg gtgcagaagc
    15961 tgttggactt taccgtacag agttcttgta catggattct caagacttcc caactgaaga
    16021 tgagcagtat gaagcataca aggctgttct tgaaggaatg aacggtaaac ctgttgtcgt
    16081 tcgtacaatg gatatcggtg gagataagga acttccttac ttcgatatgc ctcacgaaat
    16141 gaacccattc cttggattcc gtgctcttcg tatctctatc tctgagactg gagatgctat
    16201 gttccgcaca caaatccgtg ctcttcttcg tgcgtctgtt cacggtcaat tgcgtatcat
    16261 gttcccaatg gttgcgctct tgaaagaatt ccgtgcagcg aaagcagtct ttgatgaaga
    16321 aaaagcaaac cttcttgctg aaggtgttgc agttgcggat aacatccaag ttggtatcat
    16381 gatcgagatt cctgcagcag ctatgcttgc agaccaattt gctaaagaag ttgacttctt
    16441 ctcaattggt acaaacgact tgatccaata tacaatggca gcagaccgta tgaacgaaca
    16501 agtttcatac ctttaccaac catacaaccc atcaatccta cgcttgatta acaatgtgat
    16561 caaagcagct cacgctgaag gtaaatgggc tggtatgtgt ggtgagatgg ctggtgacca
    16621 acaagctgtt ccacttcttg tcggaatggg cttggatgag ttctctatgt cagcaacatc
    16681 tgtacttcgt acacgcagct tgatgaagaa actcgacaca gctaagatgg aagagtacgc
    16741 aaaccgtgcc cttacagaat gctcaacaat ggaagaagtt cttgaacttc aaaaagaata
    16801 cgttaatttt gattaatcga aaaatccctg caactcagtt acagggattt ttttgatatt
    16861 ttaaaaagaa ttttcaagaa aatctttctt atagaaagtc caaccttgaa aaagtagtgg
    16921 tcagaacaaa aaatacttaa atggttcata aaattcttga caagttggag atttaggagt
    16981 aaactattaa ccagttaagt aatagagagg agtttctgca atttagaaat gaattgcaac
    17041 tagaaatatc aaatagaaag agagtttcga tgaaaattaa taagaaatac cttgttggtt
    17101 ctgcggcagc tttgatttta agtgtttgtt cttacgagtt gggactgtat caagctagaa
    17161 cggttaagga aaataatcgt gtttcctata tagatggaaa acaagcgacg caaaaaacgg
    17221 agaatttgac tcctgatgag gttagcaagc gtgaaggaat caatgctgag caaatcgtca
    17281 tcaagataac agaccaaggc tatgtgactt cacatggcga ccactatcat tattacaatg
    17341 ggaaggttcc ttatgacgct atcatcagtg aagaattgct gatgaaggat ccaaactacc
    17401 agctaaaaga cgaggatatt atcagtgaaa tcaagggtgg ttatgttatc aaggtagatg
    17461 gaaaatacta tgtttacctt aaggatgctg cccacgcgga taatgtccgt acaaaagaag
    17521 aaatcaatcg gcaaaaacaa gaacatagtc agcatcgtga aggagggact tcagcaaacg
    17581 atggtgcggt agcctttgca cgttcacagg gacgctacac cacagatgat gggtatatct
    17641 tcaatgcatc tgatatcatt gaggacacgg gtgatgctta tatcgttcct cacggcgacc
    17701 attaccatta cattcctaag aatgagttat cagctagcga gttggctgct gcagaagcct
    17761 tcctatctgg tcgggaaaat ctgtcaaatt taagaaccta tcgccgacaa aatagcgata
    17821 acactccaag aacaaactgg gtaccttctg taagcaatcc aggaactaca aatactaaca
    17881 caagcaacaa cagcaacact aacagtcaag caagtcaaag taatgacatt gatagtctct
    17941 tgaaacagct ctacaaactg cctttgagtc aacgccatgt
//
LOCUS       DBERAE010000044        17351 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.44, whole genome shotgun sequence.
ACCESSION   DBERAE010000044 DBERAE010000000
VERSION     DBERAE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.44"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(149..328)
                     /locus_tag="ACL70N_001741"
     CDS             complement(149..328)
                     /locus_tag="ACL70N_001741"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0590501.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRME"
     gene            complement(504..719)
                     /locus_tag="ACL70N_001742"
     CDS             complement(504..719)
                     /locus_tag="ACL70N_001742"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGS0590502.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRESCQAI"
     gene            1567..2439
                     /locus_tag="ACL70N_001743"
     CDS             1567..2439
                     /locus_tag="ACL70N_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGS0590503.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2585..2929)
                     /locus_tag="ACL70N_001744"
                     /pseudo
     CDS             complement(2585..2929)
                     /locus_tag="ACL70N_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3072..3383
                     /locus_tag="ACL70N_001745"
     CDS             3072..3383
                     /locus_tag="ACL70N_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590504.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3387..4103
                     /locus_tag="ACL70N_001746"
                     /pseudo
     CDS             3387..4103
                     /locus_tag="ACL70N_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(4233..5048)
                     /locus_tag="ACL70N_001747"
     CDS             complement(4233..5048)
                     /locus_tag="ACL70N_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGS0590505.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5045..5950)
                     /locus_tag="ACL70N_001748"
     CDS             complement(5045..5950)
                     /locus_tag="ACL70N_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGS0590506.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(5951..6082)
                     /locus_tag="ACL70N_001749"
     CDS             complement(5951..6082)
                     /locus_tag="ACL70N_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGS0590507.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            complement(6196..6399)
                     /locus_tag="ACL70N_001750"
     CDS             complement(6196..6399)
                     /locus_tag="ACL70N_001750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590508.1"
                     /translation="MKIKKQTRKLAAGCSKYCFEVVDKTDEVSSKHCFEVVDKTDEVS
                     SKHCFEVVDRTDEVSNRTTVRRS"
     gene            6452..8581
                     /locus_tag="ACL70N_001751"
     CDS             6452..8581
                     /locus_tag="ACL70N_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGS0590509.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIADLEKEAEKFVCEGFATGKEALAGAVDI
                     LVEALSEDVTLRAMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYNFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNINTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKQIDTEREKVNLSLLAPNETD"
     gene            8568..9017
                     /locus_tag="ACL70N_001752"
     CDS             8568..9017
                     /locus_tag="ACL70N_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGS0590510.1"
                     /translation="MKLTDYVKQVSLEDFGRSFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            9076..9348
                     /locus_tag="ACL70N_001753"
     CDS             9076..9348
                     /locus_tag="ACL70N_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS0590511.1"
                     /translation="MNSKFYKMRRNRMISGVLVGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9702..9893)
                     /locus_tag="ACL70N_001754"
     CDS             complement(9702..9893)
                     /locus_tag="ACL70N_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590512.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10321..11079
                     /locus_tag="ACL70N_001755"
     CDS             10321..11079
                     /locus_tag="ACL70N_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590513.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11081..13069
                     /locus_tag="ACL70N_001756"
     CDS             11081..13069
                     /locus_tag="ACL70N_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590514.1"
                     /translation="MFRLTNKLAISNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKKLGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTIFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQIINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13111..13785)
                     /locus_tag="ACL70N_001757"
     CDS             complement(13111..13785)
                     /locus_tag="ACL70N_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGS0590515.1"
                     /translation="MDSNFAGRLNILRAGVLDANNGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKAPARTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(13781..14656)
                     /locus_tag="ACL70N_001758"
     CDS             complement(13781..14656)
                     /locus_tag="ACL70N_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS0590516.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNCKRSVKKSSVTKELKEKILHYHNQ
                     KFSPDKKQASINFKPAGQSIEQRPEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENRNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKYLDYKSPREDFLM
                     ANLNLKFSVRNKSRN"
     gene            15363..16838
                     /locus_tag="ACL70N_001759"
     CDS             15363..16838
                     /locus_tag="ACL70N_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGS0590517.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVVELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(16810..16935)
                     /locus_tag="ACL70N_001760"
                     /pseudo
     CDS             complement(16810..16935)
                     /locus_tag="ACL70N_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16915..17351)
                     /locus_tag="ACL70N_001761"
                     /pseudo
     CDS             complement(16915..17351)
                     /locus_tag="ACL70N_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826497.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5245 a         3212 c         3602 g         5292 t
ORIGIN      
        1 tcattgagta tgaaataaga tatgcacaaa ttgattagaa agtcaaatga atttctacaa
       61 atgttttagc aatcgtaatg tacttgtcta gattcgatct gatatatttt cgatttaatg
      121 atatggtatt taaaacctcc aaagtagctt actccattct tttacttacg tgagtgtaga
      181 tgttatttac tgttttagcg tttttgtgtt ccactctaac cattatagca ttcttctcag
      241 ctagtgtact aaggagtgtg tgcctgaaaa tatgggaact aaggggctgg tttatcggtt
      301 tctctagttt agtatttgcc ttttgcaaag tgatcttaaa tgcctttctc taaatttaca
      361 tatcactatt gtttaacaaa atctaatcta tcttaggtca cttattcttt ttttgaaatg
      421 tagaatgaac tttttcaaag tttttcgaat cttttaaaat ctgtttgttt tatatcgcca
      481 ttctccccct tttttaattc tccctatata gcctgacaac tttcccgatg gtacgaatat
      541 ggttgctttc gtctaggtgg atgtcggagt attcgggatt gagttttttt gaggtagcct
      601 tggcggagtt tcttgacata gttagtgccg tctacttgga agatgccgat ggtattatag
      661 tcaatctgtg gggtattctt gataaatagg tagtcgctgt ttcttatctt tggctccatg
      721 gacttgctga cgacataagc gattgggtcg tagtcgtctg ggataatgga aactccataa
      781 ctaaatcgtc gtcctgcatc aagcggctac ctgcagagat aaactaccta acacgagagt
      841 aagtagtctg tctgtagtcg tccagtctga tgatttttac gatacttcgt ttttctgatc
      901 atacagttgc ctctcggcat aggtcagaac tttaccttgt ctgggtggtg cccgttggtc
      961 gtagatagat tggatatcgc taggagaatc cttttgaact ggaggaaaga gggcatcaat
     1021 caagctactg aatactttaa ctaagtcaaa tatagtattt ttcttagtag acctaaccct
     1081 tttttcataa tttctaatgg tgtttttact tatacctatc ttagtaccca attcttattg
     1141 agtccaacca ttactagtct atattgtttt atagttgatt gagtttggaa tagtacgctg
     1201 tagctgctaa aacatttcta ggaattaatt tgcctttcct aatagagttg ttcatatctt
     1261 atttcaatct actatatttt tcacctctaa caatcgcaat ctcttcttta tccatgaacg
     1321 aaaacgcttt ctatctttgt aagtaaagca tcacacgaaa tccacgaaaa tgaaaacctt
     1381 tgttgtgttt tcgtaaaaaa tttgttgaca gagcacgaaa cgcctactat aattaaatca
     1441 agtttaagga aataacaaaa aaacaaatcg gagggaaaga cgatgaacac attaaatgag
     1501 aaagtaatca atatctgtaa agcagtagtt aaagaaactt taatccaaga catttaggag
     1561 aaagaaatga agaaatcaag aaaattagcc acattaggaa tctgttcagc cttgttttta
     1621 ggcttggctg cttgtcaaca acaacatgct acttctgagg ggacgaatca aaggcaaagc
     1681 agttcagcga aagttccatg gaaagcttca tacaccaacc taaacaacca ggtaagtaca
     1741 gaagaggtca aatctctctt atcagctcac ttggatccaa atagtgttga tgcatttttt
     1801 aatctcgtta atgactataa taccattgtc ggctcaactg gcttatcagg agatttcact
     1861 tcctttactc acaccgaata cgatgttgag aaaatcagtc atctctggaa tcaaaagaag
     1921 ggcgatttcg ttgggaccaa ctgccgtatc aatagttatt gtcttttgaa aaattcagtc
     1981 accattccaa agcttgaaaa gaatgaccaa ttgcttttcc tagataacga tgcgattgat
     2041 aaaggaaagg tctttgattc acaagataag gaagagtttg atattctatt ttcgagagtt
     2101 ccaactgagg caactacaga tgtcaaggtt cacgctgaaa agatggaaac attcttctca
     2161 caatttcaat tcaatgaaaa agctcgaatg ctgtctgtag tcttgcacga caatctggat
     2221 ggcgagtatc tgtttgtagg tcacgttggg gtcttagtac ctgctgatga cggtttctta
     2281 tttgtagaga aattgacttt cgaagagccc taccaagcga ttaaatttgc tagtaaggaa
     2341 gattgctaca agtatttagg caccaagtat gcggattata caggcgaggg actggctaag
     2401 ccttttatca tggataatga taagtgggtt aaactttaat agtgttatga tatgacagta
     2461 atcttaggat ttttatttct atttttgatg agttggtggg ttatttcaat cgttaatagc
     2521 cagaaaccac gcaaaaatga aacatttatt ggctatatcc aaagatacga tattgatggg
     2581 aatggctatc aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaaaac
     2641 tactttgaac aagagttact tcaacccatt ggctccgacg gattaagttg ctttcgtgaa
     2701 caccaaaatc agccgcaatt tcttcataag tgcggtattc tcgcacatat tgaagagtgg
     2761 ccataagaag gtcttctagg cttaatttag gttttcgtcc cccttttgtg tgtttaagtt
     2821 gataagcagt ttttaataca gctaacatct cttcaaaagt ggtgcgctga acaccaacaa
     2881 gacatttaaa tcgtgcatca gttagttgct tacttgcttc atcattcata gaactactat
     2941 accatatttt gtttcgcagg aagtctaatg ctaaaatctt atcagtgaga agatttctta
     3001 aagtttattc tttgtagttt catctgtatt agtacataat ttaacttaga gaaaatagga
     3061 ggactaatcg aatggaatta aaagatttta cagaaaaaga acaggaaatg attaagaaaa
     3121 ggcttacaat gtctaatatt agtgacaaag aaactactga gaagattctg gcgctagtac
     3181 cacaagactt gattaagcga atcccgtttt ttgtcagaaa acatgctaca acacgtacga
     3241 ttaaacgcat ttcaattgaa caccctgaac tctacgctgt agctcaaaca agtggtgaga
     3301 ttccagaaaa aaaacgcgaa gaattgcgtc agattatcac aactatcttt gaacaaaaga
     3361 tgaataagca tagtattaag tagagaatga aaaaatattt tattggcggt ttgggaagca
     3421 atgcctatca tagcaaggat tttctttaag aactagattc gcaggtctat tttctaaatc
     3481 catatgaaaa gcatcttcga gatgaaacag aattgaaatc atggtttaaa aatgagattg
     3541 tagaggaaga atctatctgt ctgataggtc attctattgg aggcgattta gctcgttatt
     3601 tcgcatcgga atttgaagaa gtaaagaaac tgattctttt ggatggtggc tatctagatt
     3661 tagataagat tttacctttg gatacagagt tagaggaaac taaaaattat atcaaatctc
     3721 aaattatttc ggacttagat gttcttactt ctaaagaaaa atctgaagca aagcattggt
     3781 cagaaaatat ggagaaagct gtaagacagt cctatcactg gaatgttgag tataatagat
     3841 atgagttggc tataaattat gaaaatatag aagcgatact ccgcctacgg agaaaaatac
     3901 aagcttttaa gagagaagtg ggagatacct tgtttattag tcctcgctat cctaatgaag
     3961 ctacatggag agaggaagcc ctaaaagaat tgccagacta ttttgatact atttttttag
     4021 aaaactttgg ccatgagctt tatactcaag cacctaaaga aatcgctagt ctaatgaatg
     4081 agtggctcgc ttattttcta tgagctactt gtattgctgg aaatggtata agatgaaaat
     4141 ctacaagtca ctaattttca tataacaaaa aaacgaacag gctctttttc tgttattcag
     4201 aagagaactt gttcgttttt atcttgattt tcttaaaaag ctctatatac atagggattt
     4261 tctggtttat cgactttggt aaagctgtcg atttccaagg ttggaaggtt ttgtttgagt
     4321 tctttatggt agtgattgac cagttttcct ttggctgtaa tccaggtgtt gttttcatac
     4381 tgccgggtat tgcccttggt cagcaatcca tagacaccag aatctgcgat acagtggata
     4441 atgccgaatc ggaacagaaa ttgactattg gcatgactgg ggtcgttata gacaaagcct
     4501 gtaaactgga ttgtcttgcc ctcaaattca tctggatagt cgtagatagc ctccatgact
     4561 tccatatagt tttcattagt gatctgaata ctatcttggg ataagtattt atccgccgcc
     4621 gttcgcattt ccttttcata ggctgatttt gaaaaataag aactagtatc tggtttcaaa
     4681 tattggcttg tagtcccttc acttgtctga atagctagat ccgttccttc cgataggggg
     4741 aaatgataac ctttagcaga aacggtctga gaatccaagc taacagttgg gaaagttaag
     4801 ccgatgacaa gtggaatagc cagaagagaa atactcgtca tcttggccaa tcggctgttc
     4861 agatgactgt gggttttgac ttgcttcatc cagatataca attgaacaat tgccaagata
     4921 aaggaaagca ccatggagat ataggccaga taggaatagt gcatgttgat gtactggttt
     4981 agtttgcccg acagatggag gtaaatagtc agttcaaaat agccagctaa aactaaaaat
     5041 cgaatcatag gatgactcca atcaagagag aataggctaa aacgaccaga gtcacaatcg
     5101 taatgaagtg actaataaat cgtgctttca agtaattttt catcatgaga atatttttga
     5161 tatccagcat tgggccaatg acgagaaagg ccagaactgg tgccaaaccg aaactcgaga
     5221 gtagagaagc acctataaag gcatccgcct cactacagag cgaaagaaga aaggctaaaa
     5281 gcatcaagag caggatagca aaaagaggag tcgcactgat agaggtcaga atccgagtcg
     5341 gaacgtagac ctgtattata gaagcaaaga ggcagccaaa taccaaataa cgccccgtat
     5401 caaaaaattc atcaatggcc tgcacaaaga cttgaaaaac tttttttgca gaactcaagt
     5461 aagaaaaatc atgctcatga caagccagac gattttcttt ctgaatcggt tcttgccaga
     5521 aaaatcctag aaaaattcct agtattacag ccacaagaat ggaacccaga gctcgtaata
     5581 gtgcgacatg gaaggagttg ccaaaggcag aataggtcgc aaaaagaaca atgggattga
     5641 taacaggtgc tgtcacaaga aaaggaacgg ccgtgtaact tggaaccttt ttttccagaa
     5701 aacgattgat gatggggacg attccacatt cacaagaagg gaaaagtata ccgacaaagg
     5761 tcccaaaaaa gattctcccc caacgatttc gagggagaaa atgataaacc ttgtcaggtg
     5821 tgatataaac ttcaatcagc cctgagacaa tgcttcctat cagaacgaag ggaagggctt
     5881 caatgataat ggagagaaaa atggctccag tttgaagtac actagatggg agttgttgaa
     5941 aagcagtcat ctagtttttc ttttctgctt tgactttttt ctctttgtca tcagggaaag
     6001 taacttgttt caaatcaggg agtttagcaa actcttcaaa catcttgtcc aagtcgtctc
     6061 gttttgtaaa tttgacagcc ataggtgtac ctcgattcta aattctacct ctattatact
     6121 attattttgc ggaaaaggga gttttttaat ttgttttcga tagttgatac acttcgaaaa
     6181 tctcttcaaa ccacgtcagc ttcgccttac cgtagtacgg ttactgactt cgtcagttct
     6241 atccacaacc tcaaaacagt gttttgagct gacttcgtca gtcttatcca caacctcaaa
     6301 acagtgtttt gagctgactt cgtcagtctt atccacaacc tcaaaacagt attttgagca
     6361 gcctgcggct agcttcctag tttgcttttt gattttcatt gagtatgaaa aggattggag
     6421 aaagccttcc agcttgtggt ataatagatt tatggataaa aaatatgaaa aaatctctca
     6481 ggatttggga gtgacgttaa agcaaattga taccgttcta agtttgacag ctgaaggggc
     6541 gactattccc tttatcgcgc gttatcgcaa ggacatgact ggtagtctgg atgaggtggc
     6601 gattaaggct attattgatt tggataaaag tctgacaaat ctcaatgacc gtaaggaagc
     6661 tgtcttagct aagattcaag aacaaggtaa gttgaccaag gaattggaag aagctatctt
     6721 agttgccgaa aaattagcag acgttgaaga actctatctt ccttataagg aaaagcgtcg
     6781 taccaaggca accattgccc gtgaagctgg actctttcct cttgctcgtt tgattttgca
     6841 gaatatagct gacttagaga aagaagctga aaagttcgtc tgtgaaggat ttgcgactgg
     6901 taaggaagct ttggctggtg cagttgatat cttggtcgaa gccttatcgg aagatgtgac
     6961 actgcgtgct atgacttatc aggaagtgct gagacactct aaactcactt ctcaagtcaa
     7021 ggatgaaagt cttgatgaaa aacaggtttt tcagatttat tataattttt cagagacagt
     7081 tggaactatg caaggctatc gtaccttggc tctcaatcgt ggggagaaac ttggtgtctt
     7141 gaagatcggt tttgaacatg cgacggaccg tattcttgcc ttctttgcta ctcgtttcaa
     7201 ggtgaaaaat gcttatattg atgaagttgt tcagcaatcc gttaagaaaa aggtcttgcc
     7261 tgctattgag cgtcgtattc ggacagaatt aactgagaaa gctgaagagg gagctatcca
     7321 acttttttct gacaatctgc gcaatctcct cttggttgct ccattgaaag ggcgcgtggt
     7381 tcttgggttt gacccagcct ttcgtacagg tgccaagcta gctgtcgtgg atgcaacagg
     7441 aaaaatgctg acaactcagg tcatctatcc tgttaaacca gcatcagctc gtcaaatcga
     7501 agaagccaag aaagatttag cagatttaat tggtcaatac ggtgtagaga ttattgccat
     7561 tggaaatgga acggccagtc gtgaaagtga agcttttgta gcggaagttc tgaaagattt
     7621 ccctgaagtc agctatgtta tcgttaatga aagtggtgct tctgtctatt ctgccagcga
     7681 acttgctcgt caggagtttc cagacttgac cgttgaaaaa cgctctgcca tttctatcgc
     7741 ccgtcgtttg caagatcctc ttgcggaatt ggtcaaaatc gatcctaagt caattggtgt
     7801 cggtcaatac caacacgatg tcagtcagaa gaaactatct gagagtctgg actttgtcgt
     7861 ggatacggtg gttaaccaag tcggtgtcaa tatcaatacg gccagtccag ctcttctttc
     7921 tcacgtggct ggactcaata aaaccatttc tgaaaatatt gtcaaatacc gtgaggagga
     7981 aggaaaaatc acttcacgct cccaaatcaa gaaagttcct cgtttggggg ctaaggcctt
     8041 tgaacaggca gctggtttcc ttcgtatccc tgaaagtagc aatatccttg ataatacagg
     8101 agttcaccca gaaaattacg ctgccgttaa ggaactcttc aaacgcttgg acattaagga
     8161 cctgaatgaa gaggcccaaa gcaaactcaa gtcgctttca gtcaaggaaa tggcgcaaga
     8221 gttagacctt ggtccagaaa ctcttaaaga tatcattgca gatcttctca aaccaggtcg
     8281 agatttccgt gattcctttg atgctccagt tctccgtcaa gatgtcctag atatcaagga
     8341 cttagtggtt ggacaaaagc tagaaggagt ggtgcgtaac gttgttgatt tcggtgcttt
     8401 tgttgatatc ggaattcatg aggacggtct catccatatt tcccatatga gtcgcaagtt
     8461 tatcaaacac cctagtcaag tggtggcagt tggagatttg gtgagcgttt gggttaagca
     8521 aattgatact gaacgtgaaa aagttaatct gtctctccta gctccaaatg aaactgactg
     8581 attacgtcaa gcaggtttca ctagaagact tcggcagatc ttttatccat catgtccagt
     8641 ggaataggcg tctacgttcg acaggtgggc gatttttccc caaagatggg catttggatt
     8701 ttaatcccaa ggtttatcag gaactggggt tggacgtttt taggaaaatt gtccgacatg
     8761 aactctgtca ttatcacctc tattttcaag ggaaaggcta tcaacataag gatcgagatt
     8821 ttaaggaact gttgaaagca gtggatggat tacggtttgt accatccttg cccaatagta
     8881 actccaagcc aatcaagctc tatcgttgcc aatcctgcca gcaaacttat cagcgtaagc
     8941 gaagaattga taccagacgc tatcgctgtg gactttgtcg aggtaaattg ctactaataa
     9001 atcagcctga ggactgatga aagccgagcc tacccgtgat atactatgtc taacttagca
     9061 gaaagaggaa atatcatgaa cagtaaattt tataaaatga gacgaaatcg catgatttca
     9121 ggagttttgg taggcctgtc agacaagtgg aactttgatg ttacccttgt acgttttctg
     9181 tttgccattt ttacagtcgc aaactttgga cttggggtga ttatctatat catcctagct
     9241 tctatcatgc caaccaagga agaaatcgaa gcagaaatgt acggaacagg cccacgtaaa
     9301 cgcaaagaag ctcaagccat tgacgataat gaaggctggt tttggtgagg ttttacaaaa
     9361 gatttggaat acgcaaaaag ctttaaatca atagtctaaa ctgcttgatt taaagctttt
     9421 ttacttttat actcaataaa aatcaaagtg caaactagga agccagccgc aggctgtaat
     9481 ttagtcggca atgtgaagtt aacatagttt gcactttgat ttttgaatag tattaataat
     9541 atttcgccag cttcatccac aaactatagt ggattggaac tagaatagta cacctctact
     9601 tctaaaatat tgttagaaat cgatttgact atcctgatcg atttgtcctg tttttatttc
     9661 attttattat aaaagcagta atttaaactc agttttttaa tctatttttg ctgctgagac
     9721 aatacatttt tggaaaaatg gtggatgctg ataacaactg ataaccagca aataacataa
     9781 gcagtgccgg taaattctgt accgataaag tgtgtgtgtt caactaagag ctgaccgatg
     9841 aatggagaga ggagatagag aagtccgatg agtatatgtt ctttgtgttt cattaaagcg
     9901 caccttcttt ccttataggt tgaacgactt gcaagtgtta aattgaatgg tatgttatct
     9961 aggtaagctt actcaaatga tagttcccgc ttcctccttt tcaaagtaag ccttttcaca
    10021 cttatgtttt acaactttaa aaataggaaa tcaaatcatt ttctaagtaa ttttgcttat
    10081 atttcaccca atcttacaaa aatgtaagat taaagtctct tttgtaaggt taggttatgg
    10141 caagcggtct ttttttgatg taaactagac tcataaagaa caaaggagta acatcatgaa
    10201 acaaatctta cataagaaaa ctagaaaacc aagtcacaaa gaaattgagc gcgttcagct
    10261 gggatgcact atgatgcaag ctacatttca tttgatggga tattaagaaa ggagattctc
    10321 atgacacttt tagatgtaaa acacgttcaa aaaatttata aaacacgttt tcagggcaac
    10381 caagtagaag ccctcaagga tattcacttt accgtcgaaa agggtgacta cgttgccatc
    10441 atgggtgagt ctggttctgg taaatcaact cttctcaata ttctagctat gctggataaa
    10501 ccaagtcgtg gtcaggttta cttgaatgga actgacaccg caaccattaa aaattcacag
    10561 gcctctagct tccgtcgtga aaagttgggc tttgtcttcc aagactttaa cttgctagat
    10621 actctatctg taaaggacaa tatcttgctt ccgcttgtct tgtcaagaag acctattaca
    10681 gagatgatga agaaattggt ggtgacagct gagaatctgg gtattaacca attgcaagag
    10741 aagtaccctt acgagatttc tggtggtcag aaacagcgtg tagcagtagc ccgcgccatc
    10801 atcacagaac ctgaaattct ccttgcggac gagccaacag gagcccttga ttccaagtca
    10861 tctgcagcct tacttgatgt ctttaatgaa atcaatgagc gtgggcaaac catcctcatg
    10921 gtaacccact caacagcagc tgctagcagg gccaagcgtg ttctctttat caaagacggc
    10981 attctttaca accaaatcta ccgtggagag aagacagagc gtcagatgtt ccaagaaatc
    11041 tctgatacct tgactgtcat ggcaagcgag gtgaattagt atgtttcgat taaccaataa
    11101 gttagcgata tcgaacctga ttaaaaaccg caaactctac tatccctttg cactggctgt
    11161 tctcttggca gtcaccatca cctatctctt ttactcccta accttcaatc caaagattgc
    11221 ggaaatccgt ggaggaacca ccattcaagc aacacttgga tttggtatgt ttgtcgttac
    11281 ccttgcgtca gccattatcg tcctctatgc caatagtttt gtcatgaaaa accgttccaa
    11341 gaaactgggt atatatggca tgttaggctt ggagaagcgc catctaatca gtatgacctt
    11401 taaggagtta gtgctatttg ggattctaac tgttggagca ggaatcggta ttggagcctt
    11461 gtttgacaag ttgattttcg ctttcctact caaactgatg aaattgaagg tggaactggt
    11521 cgctaccttc cagatgaaag ttgtcattac agtacttctt gtcttcggtt tgattttcct
    11581 aggcctcatg ttcctgaatg cccttcgaat cgcccgtatg aatgccctcc agctctcacg
    11641 tgagaaagct agcggagaga aaagaggtcg tttcctacct ctccaaacta ttcttggttc
    11701 cataagttta gggattggct attatcttgc ccttacggta accgatcctc ttacagccct
    11761 aacaattttc ttcctagctg ttttgctggt tatctttggt acttatctat tgtttaatgc
    11821 agggattaca gtcttcctac aaatcttaaa gaaaaacaag aaatactatt accaacctaa
    11881 taacctcata tctgtttcca acttgatttt ccgtatgaag aaaaatgcgg ttggactagc
    11941 aaccatcgct attttgtcaa caatggtttt ggtaaccatg tcagcagcga caagcatttt
    12001 caattccgca gaaagcttta aaaaagttct aaatcctcat gattttgggg tttcagggca
    12061 aaatgttgaa aaagaagatt tggacaaact cttgagccag tttgcaagtg acaaaggtta
    12121 tagtgtcaaa gagaaagaag tacttcgtta cagtaacttt ggtattgcaa atcaagaagg
    12181 aaccaagtta actatttttg aaaaaggaca aaaccgtgtc caacccaaaa cagttttcat
    12241 ggtatttgac caaaaagatt atgaaaatat gactggtcaa aaactgtctc tatcaggaaa
    12301 tgaggtcgga ctctttgcaa agaatgaggg agttaaagaa cagaaagctc taactctaaa
    12361 tgatcatcaa ttttctgtca aagaagaatt tactaaagat tttattgtca accatgttcc
    12421 aaatcagttt aatattttga ctgctgatta caattacctt gttgtacctg atttacaagc
    12481 ctttttgaac caattcccag attcggatat ctataatcag ttttacggtg gtatgaatgt
    12541 aagtatcagt gaagaagagc aactcaaagt cgctgaagaa tatgaaaaat acttacaaaa
    12601 gtttaatgct caattaaaca ctgaaggtaa ctatgtgtat ggtagcactc tagcagatgc
    12661 tagtgctcaa atgagtgtcc tctttggcgg tgtcttcttt attggtattt tcctatccat
    12721 tatctttatg gtcggaaccg ttctggtcat ctactacaaa caaatttctg aaggctatga
    12781 agaccgtgaa cgctttatta tcttgcagaa agtcggttta gatcaaaagc aaatcaagca
    12841 aatcatcaac aaacaggttt taactgtttt cttccttcct ttgctttttg ccttcataca
    12901 tctagccttt gcctaccata tgcttagcct gattttaaaa gtgattggtg tactggatac
    12961 gactatgatg ttgatcgtga ccttgtctat ctgcgctatc ttcctcatcg cctatgtgct
    13021 gattttcatg attacttcaa gaagttatcg caagattgtg caaatgtaaa aaagatacct
    13081 cgacttcaaa atcgaggtat ttcttgtatt ctaaatgctg aaaagttgtt cgagcaggaa
    13141 ggtaactccc atggtcaaga gaccaatagc taggttccga atcatagctg ttctagccgg
    13201 agcctttcca agtctggcac tagtgtaacc agtgagaaga agggccacac cgacaataag
    13261 gacagtagca gggatgcgat attcacttgg gaatatggtc actgacagca ttggaggcaa
    13321 acttctaagg aaaaaggcaa cgaagctaga aatggcagcg tgccaaggat tggtaaattc
    13381 ttcatactca atcccatatt tttcctctac cagagccttg agtggatttt taagaaagat
    13441 cttattagtc aagagttggg cagaagtttt gcattctcca ttttggatat aagcagcata
    13501 gagggatttt ttggctagtt ccctatcttg gtctagcaag agtttttctc gcgaaacggc
    13561 agcttcctcg gtatcttttg gagttgaaac ggatacatat tctccaccag ccattgaaaa
    13621 ggcaccagct aagatagccg caaaacctga taaaaagata atccagatat tggtcgtggc
    13681 actggcaact ccgataacca caccagcaat ggaaataatt ccattgttag catcaagaac
    13741 acccgcacgc aggatattta aacgacctgc aaaatttgaa tcaatttcgt gatttgtttc
    13801 tgacgctaaa tttcaagttc aagttagcca tcaagaagtc ttctctgggt gacttgtagt
    13861 ccaagtattt tttaggatag ttgttgatcc acttttcgat gaatgcgact tctttgggag
    13921 tcattttctt ggttccctta ggtaaccatc tacgaatgag cctgttgcga ttctcattag
    13981 ttcccctttc ccaagaggca taggggtgcg cataatagat gtgctcctca gaaaatacat
    14041 caaacaagcg attgaattcc gttccattat ctgccgtgat ggaaagaatc ttgtgttgtt
    14101 ttaagatgag ttttagagcc tgattgacca cctcagcact tttatttgga atcaatcgga
    14161 tgatctgatg tctacttttt cgatccgtca agacaagcaa gcagtagttt ttcgctctcg
    14221 taagtagaac cgtatcaatc tcataatgcc cattctccaa gcgaaaattg atagcttcag
    14281 gccgctgttc gatggattga ccagcaggtt taaagttgat gctagcctgt ttcttatcag
    14341 gcgaaaattt ttggttatga tagtggagaa tcttttcctt tagttccttg gtcacgcttg
    14401 atttcttgac cgagcgcttg caattgtttt cataagactg ttgagcatag tcggcagaat
    14461 aaacctcttt gaagcgccct tttccaagac attgtcggac tgtcccacgc ttgatttcag
    14521 tgtggatagt ttgaggaact tttccaagca gagaggcaat ttctctattt gatttccctt
    14581 cttttttcca tctttcgatt aagcgacggc tatcgattgt caaatgtttg gcttttgtag
    14641 tataattgtc ttgcatctct gtgcctttct tgtgtttgtg gttgaacaac aagtataaca
    14701 cagaggtgtt ttcttatgcc tacaagagct atcagctagt tgaaccatct aatttttagg
    14761 aggactgggt ggctaacttc attatagaac tttcatttac gaacatatag taaaatgaaa
    14821 caagaacaga acaaatcgat caggacagta aaatctattt ctaacaatgt tttagaagca
    14881 gaggtgtact attctagttt caatctatta tatttttgtt ttttatcaaa aaatacttta
    14941 caagttctta aaaacatgat atagtaataa agcttagaaa atgagatgat gttttctagc
    15001 aaatataaac ccgagtaaaa aatgcctacg gacaggcagg gttgaatgcc gaagcgtggt
    15061 tgaaaagcca cattattgat agggttaaaa gcctactttt ataagttgat gttaggacac
    15121 ttgtcctaat tcataaattt ttagtgtggt gaaagcacac gtcatcttgt gaaacgatca
    15181 ataaagtacg taatatttgc tactagagag ttaggaaaca tcgggaacag acatactcaa
    15241 cagaaaccaa aataaacacg tcagaagatt gcagagcagg tgaaaacctg ctcttttttc
    15301 atgagtcaac ctttagttcc ttagttttca taaggtccta aaaatattga aaggagtatg
    15361 ttttgaaaga gttagatcaa aaccaagccc caatttatga ggccttggtg aagttacgca
    15421 agaaaaggat tgttcccttt gatgttccag gtcacaagcg tggacgggga aatccagaac
    15481 ttgtcgaact cttaggagaa aaatgtgtag gcattgatgt caattcgatg aaacccttgg
    15541 ataatttagg ccatcctatt tcgattattc gtgatgcaga ggagctggct gcagatgctt
    15601 ttggagctag ccatgccttt ctaatgattg gtggaacaac ttcatcggtg cagactatga
    15661 ttctggcaac ctgcaaggca ggagataaga ttattctgcc acgaaatgtc cataaatctg
    15721 ctatcaatgc gttggttcta tgtggtgcca ttcccatcta tatcgagatg agtgtagatc
    15781 ctaagattgg tatcgcttta ggtcttgaaa atgaccgagt agcacaggcc ataaaggatc
    15841 atccagatgc taaggctatc ctaatcaaca atcctactta ctacggcatc tgttcagacc
    15901 taaaggggtt gacagaaatg gctcatgaag ctggcatgat ggttttagta gatgaagccc
    15961 atggagcgca tttgcatttc actggtaaac ttccaatttc tgctatggat gcaggagctg
    16021 atatggcagc agtttccatg cataagtctg gtgggagttt gacacaaagt tcgcttcttt
    16081 taatcgggga gcagatgaat cccgagtacg ttcgtcagat tataaacctg acccagtcta
    16141 catctgcctc ttacttattg atggctagtt tggatatttc acgtcgcaac ttggcccttc
    16201 gtggtaaaga gtcgtttgag gaagtcgttg agctatccga gtacgctcgt catgaaatca
    16261 atgccattgg cggttactat gcttactcaa aagagttaat agatggtgtg tcggtctgtg
    16321 attttgatgt aaccaagttg tcagtttaca ctcagggaat aggcttaaca ggtatcgagg
    16381 tttatgacct cttgcgagac gaatacgaca ttcagatcga gtttggtgat atcggcaata
    16441 tcttggctta tatttccatc ggcgaccgca tccaagacat cgagcgcttg gttggtgctc
    16501 tggctgatat taagagactc tattcacgag atgggaagga cttaatagct ggagaatata
    16561 ttcagcccga gttggtgctg tctccacaag aagctttcta ttcagagaga aaaagtttga
    16621 ccttagatga gtctgttgga caggtctgtg gagaatttgt catgtgctat cctccaggga
    16681 ttcctatctt ggctcctggt gaacgcatta cacgagaaat tgtagactat atccaattcg
    16741 ccaaggaacg tggttgctcc ctccaaggga cggaagatcc agaggtcaat catatcaacg
    16801 ttattaagag aaagacaaac tataagaaaa gtcaatagtt ttatctaaac tatttcttat
    16861 ttcaatttga tgatttggcg atgattttag agcacggcaa aaagcccttg aattagaagc
    16921 ggtcaatcgc ttaatttcta tcagcttatc aaatcctgcc tcaagccttt tctgaggatt
    16981 agggtagcgt gtcaagagtt ggtaggtata ttctgaatgc tttccaacga ttttatccaa
    17041 ctcaggaaag atgatatcaa gacaacgagt gtattgtact ttccaatcag actgtttttt
    17101 cttgagacga tgaatatgtc tagccagtat ttttagttct acttgccgat tatcgtgttg
    17161 aaattgttca cgattggggt cagaaagaag tttaagagcg atgccatgag cgtctttctt
    17221 atccgtttta gtcttgcgaa gtgataatga tttggcaaat tccttgatga gcaaaggagt
    17281 gtaggtgtaa actttatatc cttgttcatg caggaagttc agtagattaa aggcataatg
    17341 tccagtatct t
//
LOCUS       DBERAE010000045        17046 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.45, whole genome shotgun sequence.
ACCESSION   DBERAE010000045 DBERAE010000000
VERSION     DBERAE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.45"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(32..262)
                     /locus_tag="ACL70N_001762"
     CDS             complement(32..262)
                     /locus_tag="ACL70N_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590518.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(280..921)
                     /locus_tag="ACL70N_001763"
     CDS             complement(280..921)
                     /locus_tag="ACL70N_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0590519.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(933..1667)
                     /locus_tag="ACL70N_001764"
     CDS             complement(933..1667)
                     /locus_tag="ACL70N_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGS0590520.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1670..1867)
                     /locus_tag="ACL70N_001765"
     CDS             complement(1670..1867)
                     /locus_tag="ACL70N_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590521.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1867..2073)
                     /locus_tag="ACL70N_001766"
     CDS             complement(1867..2073)
                     /locus_tag="ACL70N_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0590522.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2083..2550)
                     /locus_tag="ACL70N_001767"
     CDS             complement(2083..2550)
                     /locus_tag="ACL70N_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590523.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKMCYNEFKLRN
                     RKQKGVIMWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(2550..2741)
                     /locus_tag="ACL70N_001768"
     CDS             complement(2550..2741)
                     /locus_tag="ACL70N_001768"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590524.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDETDEVS
                     NYTYGKVKLTWFEEILEEY"
     gene            complement(2738..4027)
                     /gene="hisS"
                     /locus_tag="ACL70N_001769"
     CDS             complement(2738..4027)
                     /gene="hisS"
                     /locus_tag="ACL70N_001769"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGS0590525.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4105..5352)
                     /locus_tag="ACL70N_001770"
     CDS             complement(4105..5352)
                     /locus_tag="ACL70N_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGS0590526.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5543..6394)
                     /gene="rgg"
                     /locus_tag="ACL70N_001771"
     CDS             complement(5543..6394)
                     /gene="rgg"
                     /locus_tag="ACL70N_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGS0590527.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6518..6859
                     /locus_tag="ACL70N_001772"
     CDS             6518..6859
                     /locus_tag="ACL70N_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS0590528.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            6923..7087
                     /locus_tag="ACL70N_001773"
     CDS             6923..7087
                     /locus_tag="ACL70N_001773"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590529.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKYCFEVVDRTDEVS
                     NHTYGKATLT"
     gene            complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL70N_001774"
     CDS             complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL70N_001774"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGS0590530.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9049..9981)
                     /locus_tag="ACL70N_001775"
     CDS             complement(9049..9981)
                     /locus_tag="ACL70N_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGS0590531.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(9978..10835)
                     /locus_tag="ACL70N_001776"
     CDS             complement(9978..10835)
                     /locus_tag="ACL70N_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS0590532.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(10839..12185)
                     /locus_tag="ACL70N_001777"
     CDS             complement(10839..12185)
                     /locus_tag="ACL70N_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0590533.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(12198..12482)
                     /locus_tag="ACL70N_001778"
     CDS             complement(12198..12482)
                     /locus_tag="ACL70N_001778"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590534.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(12486..14516)
                     /locus_tag="ACL70N_001779"
     CDS             complement(12486..14516)
                     /locus_tag="ACL70N_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0590535.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            14707..15714
                     /locus_tag="ACL70N_001780"
     CDS             14707..15714
                     /locus_tag="ACL70N_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS0590536.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            15717..15917
                     /locus_tag="ACL70N_001781"
     CDS             15717..15917
                     /locus_tag="ACL70N_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0590537.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            16069..16251
                     /gene="rpmF"
                     /locus_tag="ACL70N_001782"
     CDS             16069..16251
                     /gene="rpmF"
                     /locus_tag="ACL70N_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGS0590538.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            16267..16416
                     /gene="rpmG"
                     /locus_tag="ACL70N_001783"
     CDS             16267..16416
                     /gene="rpmG"
                     /locus_tag="ACL70N_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0590539.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(16896..>17046)
                     /locus_tag="ACL70N_001784"
     CDS             complement(16896..>17046)
                     /locus_tag="ACL70N_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590540.1"
                     /translation="YYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNAN
                     GEWVG"
BASE COUNT         5522 a         3588 c         2915 g         5021 t
ORIGIN      
        1 acaaaaatcc gatgaacttc accggactct tttattttga atttttgcct gctttacgct
       61 tttcagcgat ttcggctgcc tttcgaggca agacaatttc cgttatgtaa gccgtcccaa
      121 aacgcagtac acctgcaata ggagcaaaga caactgctag atagttatag aagaaatcgc
      181 ctttgaaggc ataagctagc gctccaatga tgaaaaatag aacgactgcc tgaatcactg
      241 ctaataaaat tactcgtttc atgtgacctc ctgactctat tatagcatga gaatcatcaa
      301 aaagccgact aaattattca aagcgtgaag agaaatactg tagaccagac cttttctgct
      361 aatgtaagcc aaacccaaac taaaaccaag gctaaaatag acaaaaaatt gttgcacatc
      421 acctggaaaa tgaatcaagg caaatagaag actagatacc agaagaaaaa tcagggttcg
      481 tttactattg tcctgcttag gaaagagata gcgtgctaac atccctctaa aaacaatctc
      541 ttccgtcaaa ggagcaaaaa taaccacagc aaagaatgag aaaagtggtt gagacaaggt
      601 caagtctgtc gctatttgct gatttactga aggatcatct ggcaagaaga attgaacgac
      661 cagagataag aaccaaacca aggcaggaag ccaaataaat cggttaaagc cgctcttctc
      721 aatataaaca ggagctttct gataccattt gtaaatgccg tacacatata ctccagccaa
      781 gaccacatag agtagagtaa cagcataggg tgaagcgcct aaagcaagcg acgcagtcgc
      841 gagcccctga ataaagccat agataaagaa aaaggataga agggctagaa gaatccagcc
      901 aaggttttta agtaatttca tagataactc ctttatttga aataacgttt taccataggt
      961 aactgcatca cattgatata aacatggatg gctcctacaa gcaagaaagc tagtaactga
     1021 atctctcctg tcaagaaaga aatgataata agaaaaatat ataaggctgg taagacatat
     1081 tggtgtaatt ggaataaaat tcgaaaactc tgttccaaat tagcctgacg ctccccttca
     1141 tcataagaat ttatatagtt caagacatcc tttggtgtag cgaaaaattc caaatcaaac
     1201 tgacgaacaa tcgcaatggt tttaaaaaga gatttttgag cgactaagaa taccacaaag
     1261 agtaagaaag aaaggaaaaa tgtttgaggg tttgtatgca atataatcac ctcacttaat
     1321 gaaataaaaa tagccaatgg aatcgctaca cctgtaatat taaaagcaat ggttccaaac
     1381 tcaagattcc gatacatttg cacataatag gtttcattca gatcgtcatc catttcctct
     1441 tgatacaagg aatgaaattt tctgcttttc tttaagaaat tgaaagtcaa aaacatacta
     1501 atgaaaccta tcagtaaaca aatagctgat atccatggca tcaaggcttt tacatctaaa
     1561 ataatttcgt gggattcgac acgtgcctta aacatcccta caaacatgcc caagaacccc
     1621 cccaagacaa tagacatcaa aaataacaat ctacgtttct ttttcatatt cattctcctt
     1681 tttcacttgc tagatttttg gatttctttt caatccattc agttactggg atgagagcaa
     1741 agtagaccca aacaaattgg tcgctttgat agggattaaa ccagcttagg tccatcccaa
     1801 tcagtagaaa tacgctgact aataaagcta tgaccactac ataataaatc actttatact
     1861 tgttcatcac tcgtcctcct ccaaacgaaa taccgattcg actgtttcgt tgaaaatttg
     1921 agatattttc agggcaatga taatggatgg ggtgtactca tcccgttcta gtaggctaat
     1981 ggtctgtctg gaaacccctg ccagtttggc taggtcggtt tgattgagac catcgcgagc
     2041 tcgaagctct tttagacgat tttttagttg catgttacac acctactctc cgtcaaattc
     2101 aacggtttgg atatcttcaa tacgttgcaa cttgaatttt tctttcccct ttttatcaac
     2161 actacgtagt ttgacccatt cctcgtcaac atccacaact tcccagttat ctggcccaat
     2221 atacactccc gttataattg gttcctttcc aatcatttct tgcaataatc tcgacatttc
     2281 tgcgtttcct ttctcttttc gctcaagttt tttgatttta ttctctagtt tcttgatttt
     2341 tttagaatta ttagaataaa agaaaatcat aaatagtata aatactagta cccacattat
     2401 aactcctttc tgcttcctat ttcttaactt gaattcattg taacacatct ttttcttttt
     2461 gacaattata gttgtcaaaa agtttatgat ttttgtcatt ttgcaaaaga aaaaggtcag
     2521 gagtaagttc ctgaccactt tatctatcat taatactctt ctaaaatctc ttcaaaccac
     2581 gtcagcttca ccttgccgta ggtatagtta ctgacttcgt cagtttcatc tacaacctca
     2641 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
     2701 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa aatcctagtt
     2761 tttcaaagat ttctgagaag ttttggctga ttgtctcaag tgacacttgc acttcttctc
     2821 gggtttggtt gttcttgacc gtcacttgtc cgctttcgac ttcgctctct cctagggtga
     2881 tgagggtctt agccgcaaag acatctgctg acttgaactg agctttgagc ttacggttga
     2941 ggtaatcacg ctctgctttg aaaccttgtt ggcgaagagc ttggactagt tctagggctt
     3001 tgacatttgc tccatcaccc aagactgcga tatagacatc tagggcgttt tcgataggga
     3061 gggccacgcc ttgtttttca aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa
     3121 atccagcagt ttcagggcct ccaaagtaag caaccaaacc atcgtagcga ccacccgcac
     3181 agactgtcaa gtcattgccc tcaatctctg tgataaactc gaaaatggtg tggttgtagt
     3241 agtccagacc acgcaccata ttggtatcga tgatgtaatc tactccaaga ttttccaaca
     3301 tctgacgcac agcatcaaaa tgagtttggc tttcttcatc aagaaagtcc aagatagacg
     3361 gcgcattctc tactgccacc ttgtcttctt tttccttaga gtccaagaca cgaagaggat
     3421 tttcctccaa gcgacgttgg ctatccttag acaaggtctc cttgagcggt gtcaaatagt
     3481 caatcaaggc ttggcggtag gctgcacggc tctcaggatt tccaagagtg ttgaggtgca
     3541 atttgacacc ttgaataccg atttccttca aaaaatgggc tgccataacg attgtttcca
     3601 catcggtagc tggattgcta gagccaaaac actcaacacc aatctggtgg aattggcgca
     3661 agcgccctgc ctgtggacgc tcataacgga acataggtcc catgtagtag aacttgcttg
     3721 gcttttgcac ttctggggcg aagagtttat tttccacata ggaacggaca acgggcgcag
     3781 ttccttctgg acggagggta atatggcggt cacccttgtc atagaaatcg tacatttcct
     3841 tggttacgat atccgttgta tctccgacag agcggctgat aacctcgtaa tgctcgaaaa
     3901 taggcgtacg cacttctgcg tagttgtagc gcttgaaaat ctcacgggca aagccctcaa
     3961 cgtactgcca cttagcagac tcagcaggta aaatatcctg cgttcctttt ggtttttgta
     4021 atttcatagg gaatcctctt taaacttaat agtcttattt taccataaat agagggatta
     4081 aaacagtgag aaaaaaatta ggatttagat atcatttttg agattaagaa ttgtcaaaaa
     4141 aatagctagc aaggaaagac caacaaatag catccaagtc aactgtatat tccatacggc
     4201 tactagtgaa aaacaagctg ttcccacagg tatggataag gtaaacaata gatctaaaaa
     4261 attactagta cgagctagaa cctctggagc tagatttttc atgagcatgg cactaatctt
     4321 tggttgaact ttaccagaca catacagagt aaagaagaga aatagcaaac caagcacgac
     4381 ttgattgaat aaattagcca aaccaactag actaagtcct acagtcgccc acatcatcaa
     4441 tctaggcaag gactgcttcc caaaataagc attgcccgta aggctactga tgatgattgc
     4501 tactaaaaca cagaattgat tgataaatag tgcctctgta taagaaaaat tcaagagaga
     4561 atggctcaaa aagaagatat tataaattcc acccaaagcg ccacccaagg aattaataag
     4621 caagacagca aagagcataa aaccaaagtt tttctgccca cttttaagaa aaacgagacg
     4681 taaatttcgg taaattgtta ggaactggtc tttgatagaa agcttctcat tttttaagtt
     4741 ttcaccatca gcagatgaca ttgacaggct caatttgctt tttcctaaaa agaggatagt
     4801 ggctgatact aggaaaaagc aggcattgat tcccgcaacg agagaaaaat tgttgaccga
     4861 tagagctaag agccagactc cgaaagcttg accaccaata gctgaaatat aggtgatgaa
     4921 ctgtgaaaaa gaataagcct ccatcagatc atcttcagct actttttcct taataagagg
     4981 catacgcagg ccacctgcaa aatcactgat gatatcacta atgacattga tcaaacacag
     5041 gctagaaaag gcaaagagac tagcttgctg aacaactagg gctgctagaa aaaatagaac
     5101 cgcctgaaac aaaccgctat agaccatcca tttgaccttg tccctcgtgt aatctgcccg
     5161 aatccctgca aaaactgtaa agaaggtcgg aagaatcatg acaatattcg ccatagcaac
     5221 agcaaaagat gcttgtgaca aggtcgatgc atagacgata aagaccaggt tgaaaatcga
     5281 agcaccaaaa gcattgaaga agcgtgataa agtcaaaatt ctataagctg gatttctaaa
     5341 caatagtttc atagataatc tccctccttg ttctaagttc tacatcaaga atagctttag
     5401 tatagcactt atgaatttgc gaaacgattc ttttgaatat atgcaacaaa caaaatgagc
     5461 aaaaaaacga tagaactttt gtaatgacct gagagagggt aacagttcta tcgcttcaaa
     5521 ttttttcttg gtttgcagat actcaacatt cggtcgtatt tctatagtat tcggcagatt
     5581 tattacagcc aagcatctca aaaatacgga cagcatcctc catctttttc tggccttcct
     5641 tgactctacc ttgcttgcta tcaaggagac cttctgccca cagataaaca attcggaaat
     5701 aggtctcatt ttccttgtag aaatgctctt cgataacacg tttaaaataa taggcattgg
     5761 taaattcttc acactcaata ctagctaaaa agccattcaa tagtatagta tgaaaaaggt
     5821 ttcgattgcc agacatttcc attagaaaat cagatttacg taccatttct cgtacatatc
     5881 tagtaaaaag agaaacagat aaaaatggag aactgactga aaataaattg agttcataga
     5941 ttccccagat ctcggtagaa aacaaataat catgaaggac ttttccttcc tctgctgtta
     6001 actctaccct ttcatctatg ctcttcatat aagacttgat aataatggca tttagaatat
     6061 gtttctgttt gttgtgagaa tgggcatgct tttgatactc cctgcgatat aagtcctcaa
     6121 gaggtgctat attctttggt tccaagacat ctgtaatttc ttttctcaac tcagaatctg
     6181 tatcatactg gaaacctctc gccagaaaga ggatctcctc cacactggca gatatatttt
     6241 ccagagcaaa tagaaacttt tccaccaaaa gctcactctg acctgtttca aaacgggaca
     6301 acatagacgg cgaaaattgt cctccggttg cttgtctcag tgagatattt cttgactctc
     6361 gtaattgtct aaagactttt ccaatctgct ccatagactt ccccttgatt ccgtattttc
     6421 ttcattttat catatttttc agaaaattca tcaaaaactt gccaaattgt cagaattatg
     6481 agaaaataga ggatatttat cacgtggagg gactgctatg agagacgata tcaaaatcaa
     6541 tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa ctagagaaag tttttgatac
     6601 agatgtggaa ttggatgttt acaatctagg tctgatttat gaaatcaatc tggatgaaac
     6661 ggggctctgc aagattgtca tgaccttcac cgatactgcc tgtgattgcg ccgaaagcct
     6721 gcctattgaa atcgtggcag gtctgaaaca aatcgagggt atcgaagata tcaaggttga
     6781 agttacctgg tcgcctgctt ggaaaatcac acgaatcagt cgctatggcc gtattgccct
     6841 tggactacca cctcgttaag caggccaatc acttttaaag atgaaaaaag caagccgaaa
     6901 atggcttgct ttttgatact caatgaaaat caaagggcaa actagaaaac tagccgcagg
     6961 ttgctcaaaa cactgttttg aagttatgga tagaactgac gaagtcagct caaaatactg
     7021 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca aggcgacgtt
     7081 gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt gtccatattc
     7141 cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata tttaccgagg
     7201 acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc aagttcttct
     7261 tcggatacgg ccatggaaat ttctttggta tcttggtcaa ccgtaacgat atcgccggta
     7321 cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc aacaaccaga
     7381 ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc tccctgacct
     7441 ttaccaacaa tcattgaaga aagtgacagc atctcaggca taccaggacc acctttaggt
     7501 ccaacaaaac gaacaacgac tacatcgcca tcaatgattt catctgtcag gacggcctga
     7561 atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg cactttaaca
     7621 cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat gataagcgga
     7681 ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg agtcaagtct
     7741 gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg atctccgtga
     7801 aggaaaccat ttgccaacaa gtacttcata accgcaggga caccaccgac ttcgtagagg
     7861 tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac acgttcttga
     7921 atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat ggcgagcaag
     7981 tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtaatagc atcttcaaag
     8041 gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt aacaacagca
     8101 cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg agaggatgac
     8161 cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc agtatacata
     8221 ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac gtcctcagct
     8281 gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa gtcgatatct
     8341 ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc tgggatatcc
     8401 atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc gatagcgacg
     8461 aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat gatgtcacga
     8521 gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc tacggtaatg
     8581 gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc cagtttcccg
     8641 aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat cactcccaca
     8701 atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc acggttaggt
     8761 gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc agtcatctta
     8821 tccctcccat ttcagttttt actattatag cacaatttaa aggcaatgaa cagaataaaa
     8881 ttcttgaatt ttcagaaaat tctatacgca tgtgaaatat ttaaaattaa aaacaacaaa
     8941 gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt ctttaaataa
     9001 cgtactgtaa tttttacaga aattctttca gataagtgta tttaacatct atcttgcatt
     9061 ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact cattaagaag
     9121 ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat gaatttttgt
     9181 tattccatca tcagagaata attcacataa agcactgcca attccaccta tctgattgtg
     9241 gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt ctggtatcgg
     9301 tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca gttcatctgc
     9361 aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat cttcaccatg
     9421 tcttaactca atgtagccct tagaaaaatc ttctccacct tgatatacag cctctggagc
     9481 ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctgat tcaatatttc
     9541 acgaaattgg atatcatcag ttgcttcaaa aatgattgat ttaggaatta aacgtaacaa
     9601 tccaatttct tcaaatggca tatgtgtccc accattcatt tctgcagtta ctcctgcatc
     9661 tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata attgatcaaa
     9721 tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc cctgaataga
     9781 caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca cataacggtc
     9841 tccaaagttc ttttcaagat tattagtagc catcgaactt gacaaatcgg cttctaagac
     9901 tactatatca gaataacttt gattagcctc taaaaggaag tctctatata catgccgtaa
     9961 ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct ttctacaact
    10021 gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga tttcatttct
    10081 tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt aggtgatgaa
    10141 ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc tgaacccttg
    10201 accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc tggattacaa
    10261 atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac aattaagttg
    10321 gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc atttaactca
    10381 ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg accatatgca
    10441 agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc tatgcctggc
    10501 gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa agaatataag
    10561 aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg tcctccatga
    10621 ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg agtcattggc
    10681 attatttcac cataaagcac tgctaaaact tctacgatag acagacttcc tccgtaatgt
    10741 ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt cgcaaatttt
    10801 cttaacccat cttctctatt tttacttaaa atcatccctt attcctcctt tgcagatggc
    10861 tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc aatcacaata
    10921 cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag accaaaatct
    10981 gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat taaaaagact
    11041 ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggcgcc acgaacacca
    11101 ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg cacaacacct
    11161 ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa accaccaaca
    11221 aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac aatcggacaa
    11281 tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa ggctggaaca
    11341 atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc tgcaaattga
    11401 cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc tttttctata
    11461 tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga taaagtgata
    11521 ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc ctctgttgat
    11581 tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc caaagaactg
    11641 aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt ttgcacaaat
    11701 gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat gagaggcaag
    11761 ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata tagagtgtgg
    11821 tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat attgaacacc
    11881 atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc tacagctaca
    11941 attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa catggtacca
    12001 aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa gaaaccaaca
    12061 aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag aactaatcct
    12121 aaaattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa tatgaacttc
    12181 atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt aattaattct
    12241 cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag atgactagct
    12301 gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc tgctccacct
    12361 aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac agattcaata
    12421 ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc aatttttaac
    12481 attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt tgatgatatt
    12541 aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa agcctttaaa
    12601 tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg ttctggatta
    12661 tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc attcacacct
    12721 tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa aggtccaaac
    12781 tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc ttgatccaaa
    12841 agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga actaacctga
    12901 taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct atcatttttt
    12961 tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat aattccatat
    13021 cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa attcggaaaa
    13081 tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat aaccgaaact
    13141 agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc atagtcacta
    13201 ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat ttgaggaaat
    13261 aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg acaaatgatt
    13321 gctgctttat agcatttttg aggcaaagta tctgctttct ttaaataacc tccgaaatgg
    13381 ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc catcaagggc
    13441 atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac atgcaataca
    13501 tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat aaggtggcgg
    13561 cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat atcttccatt
    13621 ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc tacttcacct
    13681 tcaaagcaac ttgataataa aactgtgata tagcgataat catcctcaga aaacaccgta
    13741 tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc ttgaataaca
    13801 ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata cctacacaga
    13861 atgaatacta aaccgaaaag gcaaactttt aattgattaa caataggtac tagttgtagc
    13921 ttctcataat aatctttaac tacctgattt atcaaatcat aagttaatga atacccccaa
    13981 ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa ctcactaacc
    14041 atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata accttttgct
    14101 ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga ttgaatatca
    14161 gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt cgatataaaa
    14221 tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt tggtaaaacc
    14281 aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga taaactatag
    14341 cgaccttgtt ttttatccag cactatccct ttattagcta gataaggcac taaataatct
    14401 attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc atataatgat
    14461 agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc aaacatttct
    14521 cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt atttgagcac
    14581 aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg attattttca
    14641 actttctatt gacttttaaa aacaaagtga tatcatttag atatcaaata atgggaggtc
    14701 attcttatga ctgaaaaact aatcaattca aaaccaaatg gtgtattcgc attgattctc
    14761 attgagttga caatcgtact tggtgtcttt atatttataa tgggtgttgg ttcggaaaac
    14821 atttttggaa ttattatcgg acctttacta atcgtaattg caggtctagc tcatgctggt
    14881 ttaaaagttg tcaaacctca ggaagctctg gttctgacac tctttggtaa ttatacaggt
    14941 accatcaaag aacctggttt ttactttgtc aatcccttca gcgtagcagt caaccctgca
    15001 aaccacactc gacttggaca aagtggtgat gttagcacaa aatctccttt tttaggagct
    15061 aaatcatcaa atgacaatga tgtaaatctt gaaattggca agaaacacat ttccctcaaa
    15121 gtcatgacct tgagcaattc tcgtcaaaaa atcaatgatt gcttaggaaa ccctgtagaa
    15181 atcggtatcg cggtaacttg gagagttgtc gataccgcta aggcagtctt caacgttgat
    15241 aactacaaag aatatctttc actgcaatgt gatagcgccc tccgtaatat tgtccgcatc
    15301 tatccttacg atgtgtctcc taatgtggat actacgggtg acgggcaagc agatgaaggt
    15361 agtctccgtg gctctagcga aattgttgct aaccgtattc gtgaagaaat ccaaagtcgt
    15421 gttgaggatg ctggcttgga aatccttgaa gcacgtatca cttacctagc ttatgctcca
    15481 gaaattgctg ccgttatgct tcaacgccaa caagcatctg ccattattga tgcacgtaag
    15541 atgattgtag atggtgctgt aggaatggtt gaaatggcac tagaacggct caatgaaggg
    15601 gaattggtag aacttgacga agaacgaaaa gctgccatgg tttcaaatct ccttgtcgtt
    15661 ctttgtggca atcatgatgc acaaccaatt gtcaacacag gaagtcttta ctaaagatgg
    15721 ctgaagctaa aaaaaagcag atcccccttc gactctcaac aaagttatac gctgcactcg
    15781 catcatgggc agaagacgac tttcgttcag tcaatggcca aatcgaatat ctcctcacag
    15841 agtgtgtcaa gcaacggaag aaagacggaa aatacgtatc agaaaccatt gacgaaccat
    15901 ttgagattga tatttaacac cttctcctgt ctgccgtgtc ggataggaga attttttcat
    15961 ctttttttgt caagtaactt tactttacaa aaaaaatgtg ttatcctagt atggttgatg
    16021 aaaatcagta gattgaatcg aatataaata cctaaaggag aaatcaaaat ggcagtacct
    16081 gcacgtcgca cttcaaaagc gaagaaaaac aaacgtcgta cacactacaa agtaacagct
    16141 ccatctgtaa actttgacga aactactgga gattactcac gttctcaccg tgtatcactt
    16201 aaaggatact acaaaggacg taaaatcgct aaagctgcat cagctgaata atagaaggga
    16261 gataccatgc gcgtaaatat tacacttgaa cacaaagaat ctggtgaacg cttgtacctt
    16321 acttctaaaa acaaacgtaa cactccagac cgccttcaat tgaagaaata ctcaccaaaa
    16381 cttcgcaaac acgttgtgtt tacagaagtg aagtaagcat tcaatacgaa tcaatacaga
    16441 agaaaaacgc ttgatcagcg ttttttcttt ttgttaattt cactatattg caagagaaat
    16501 cattcgaatg actacatttt ttgaaataag aatacggatt cggacgatta aaagtaagag
    16561 aaactcaaat gtaagttggg gttccttttt tgtatatttt tcaaataacg cctctacact
    16621 atttgtagca aattcaccaa ctacagttgc atcttagtta aaataagtta gaatatgtaa
    16681 gtgagtacca gatataccaa gacatcgtca ccatctaagg tatattcaaa atacaaaagt
    16741 tgaccaacta gatttctgaa tatccttata tatccattct taaaattggt ttaaatagcg
    16801 tagtctttta aactagtttt gagaatccaa aaaatcttcc tacatatgta agaagatttt
    16861 ttagttcaga atgattagat ttagctaatg gatacctatc ctacccactc accgttagca
    16921 ttgactcgat agccatcggg tgtagtcgtg tttactaata aatctcctga attataggta
    16981 tagtaccatt taccagaaac tgtaaaccaa ccagtagcca ttgaacctga ttcatttaag
    17041 taatac
//
LOCUS       DBERAE010000046        15947 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.46, whole genome shotgun sequence.
ACCESSION   DBERAE010000046 DBERAE010000000
VERSION     DBERAE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.46"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..122
                     /locus_tag="ACL70N_001785"
     CDS             <1..122
                     /locus_tag="ACL70N_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0590541.1"
                     /translation="IKLIKRNAFGFRNFENFKKRIFIALNIKKERTNFVLSRA"
     gene            complement(262..555)
                     /gene="rpmA"
                     /locus_tag="ACL70N_001786"
     CDS             complement(262..555)
                     /gene="rpmA"
                     /locus_tag="ACL70N_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGS0590542.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(572..916)
                     /locus_tag="ACL70N_001787"
     CDS             complement(572..916)
                     /locus_tag="ACL70N_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGS0590543.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(932..1246)
                     /gene="rplU"
                     /locus_tag="ACL70N_001788"
     CDS             complement(932..1246)
                     /gene="rplU"
                     /locus_tag="ACL70N_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGS0590544.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQVVYVEKLNVEADQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(1282..1369)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(1464..2063)
                     /locus_tag="ACL70N_001789"
     CDS             complement(1464..2063)
                     /locus_tag="ACL70N_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGS0590545.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            2533..2832
                     /locus_tag="ACL70N_001790"
     CDS             2533..2832
                     /locus_tag="ACL70N_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGS0590546.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            3051..4128
                     /locus_tag="ACL70N_001791"
                     /pseudo
     CDS             3051..4128
                     /locus_tag="ACL70N_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4444..5418)
                     /gene="pta"
                     /locus_tag="ACL70N_001792"
     CDS             complement(4444..5418)
                     /gene="pta"
                     /locus_tag="ACL70N_001792"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGS0590547.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(5462..6358)
                     /locus_tag="ACL70N_001793"
     CDS             complement(5462..6358)
                     /locus_tag="ACL70N_001793"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0590548.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(6355..7173)
                     /locus_tag="ACL70N_001794"
     CDS             complement(6355..7173)
                     /locus_tag="ACL70N_001794"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGS0590549.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(7157..7828)
                     /locus_tag="ACL70N_001795"
     CDS             complement(7157..7828)
                     /locus_tag="ACL70N_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGS0590550.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            7956..8525
                     /locus_tag="ACL70N_001796"
     CDS             7956..8525
                     /locus_tag="ACL70N_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGS0590551.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8638..9597
                     /locus_tag="ACL70N_001797"
     CDS             8638..9597
                     /locus_tag="ACL70N_001797"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS0590552.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            9607..10722
                     /locus_tag="ACL70N_001798"
     CDS             9607..10722
                     /locus_tag="ACL70N_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS0590553.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            10727..11074
                     /locus_tag="ACL70N_001799"
     CDS             10727..11074
                     /locus_tag="ACL70N_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGS0590554.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            11082..11297
                     /locus_tag="ACL70N_001800"
     CDS             11082..11297
                     /locus_tag="ACL70N_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS0590555.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            11380..12021
                     /locus_tag="ACL70N_001801"
     CDS             11380..12021
                     /locus_tag="ACL70N_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGS0590556.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            12039..12728
                     /locus_tag="ACL70N_001802"
     CDS             12039..12728
                     /locus_tag="ACL70N_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS0590557.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(12725..13405)
                     /gene="radC"
                     /locus_tag="ACL70N_001803"
     CDS             complement(12725..13405)
                     /gene="radC"
                     /locus_tag="ACL70N_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS0590558.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(13448..15739)
                     /gene="pcrA"
                     /locus_tag="ACL70N_001804"
     CDS             complement(13448..15739)
                     /gene="pcrA"
                     /locus_tag="ACL70N_001804"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGS0590559.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         4924 a         3409 c         2952 g         4662 t
ORIGIN      
        1 tcatcaaact tatcaaacga aacgcctttg gatttcggaa ctttgaaaac ttcaaaaaaa
       61 ggatttttat cgctctgaac atcaaaaaag aaaggacgaa ttttgtcctt tctcgagctt
      121 agctgacttc aacccactac agttgacaaa gagcctaaaa aaacaggctc tccgaaaact
      181 cggaaagcct tattttaagc tgtttctagc ttcctcacct ttatatttca aggttcggga
      241 taaaaggttc aatggacctt tttatttagc gattgggtaa acagaaactt gttttttatc
      301 gcgtccttta cgttcaaagc gtactacgcc ttcaacttta gcgaacaaag tatcgtctcc
      361 accacgacca acgtttacac ctggatagat gtgtgtacca cgttgacggt aaaggattga
      421 tccacctgtt acagtttgtc cgtcagctgc tttagctcca agacgtttcg cttgtgaatc
      481 acgtccgttt gatgtagaac ctccaccttt tttgtgggcg aaaagttgca agttgttaag
      541 agtcattttt aacataatgt tttcctccgt gttagttttc tgtgataact ctggtttgga
      601 cgaactcaga agagttctcc gataagtttg ccatacctaa gaaaaatgat tcaaagaata
      661 actgggtcat ttctctctgg tgtgaaggaa gatcttttgg tatttcaacc atcagatagc
      721 caccttcatc ttcgtttaat tctaggattg gttcatagcc tgcaaatttc tcaatagaat
      781 tgataaagtt aatggcaagc gtagaaaccg atgcacacac gacatctaag ccgtattcgc
      841 cactctcggc gtgtccagta atttccgcac tcctcagctc gccatcttcg gctctctcaa
      901 agactgcctg tatcatgtgt tctccttaaa attaagcgtt gattgcgttg atgacaactt
      961 ttgtatatgg ttgacggtga ccttgtttac ggtggctacc ttttttaggt ttgtacttgt
     1021 aagtaaccac tttcttttgt tttccttgtt tttcaacagt tccaactaca gtagctccag
     1081 caacaagtgg agttccgaca acagtgtttt caccaccaac aagaacaact tcgttaaaag
     1141 taacttcttg atcagcttca acgttcaatt tttcaacgta aactacttga ccaacttcaa
     1201 ctttaacttg ttttccgcca gttttgataa ttgcgtatgt gctcattatg cacctcctat
     1261 gatttttatg ggtttccccg attttttgtg aagactcgcc tagcatcgtg ggacgaacca
     1321 cttaaacttg aataatcaag caacgatgtt cgtgcggttg cacaggatcg tgcatagtca
     1381 actcttcaag tatagcatat ctcctatttt cttacaagta ataacaccta aaatgaagct
     1441 ttttctttta cttttttctg ccactaggca aaaagcatac tgagataaaa aatgctcatc
     1501 ataataggaa caccaagaat ggtcttttca tgatagaaaa tcgtcaaata ggctgaaaag
     1561 acatcgccaa ggacaaaact actaagcagg ctaacaaata tgaacccttc acgcaaaaaa
     1621 ggagtgtgct tagttcggaa ataatctcca aaagctagca ttgttcgttt gatattccct
     1681 gtcataaagg cattattgta ggcaataccc gaaacctcac caaaagcagt tgtcaccagt
     1741 cccatacaga aggccaaggg ctgcactaga tagatattat ctacagtttg tggcacaaaa
     1801 ccaataatta ttgataggat tgctaaagga atcaaggaca gaataggttt tttcacaatt
     1861 ctcaattttt ccttataaat cgttaataaa aagactccca ttataaacgt tattaaggtt
     1921 aaaagcttat ccctaacatc cgaaacatta ttttgtatta gctctaccga aagaaagaca
     1981 acatttccag cttgtccagc tacaagggta ttccctcgaa caataaaagt gtaagcatcc
     2041 acatatccag cacaaaatgt caaaaaagtg ctaacctttt agactgacgt gatatttttc
     2101 ttataggtaa taacctcatt ttccctccca ttgtattttc tcttagaaat attgtaccat
     2161 ttctttctaa aaaatcgtag actaccattt agattttact attagcataa aaataataat
     2221 agacaactat ttatccaaaa atagatagag gtaacatgtt tgcaaacaaa gcatacgaac
     2281 ctttagtaaa atcatttcca tgaaactaga atagagcccc tcttagcaaa aatcattatt
     2341 ttaatttatt tctaatcact ccttgacata aataactctc accaataaaa gactatgtct
     2401 taaaaaaatg gtataataaa atcaatacct gggcttgatg gctatgctac taataacaat
     2461 taggagagaa aatcaggcac ttgttaacaa caaggattat ccccttgaga tgaaaggaac
     2521 tttagaaatc ttatgatgaa catgcaaaac atgatgcgtc aagcacaaaa acttcaaaaa
     2581 caaatggaac aaagccaagc tgaacttgct gctatgcaat ttgttggcaa atctgctcaa
     2641 gatcttgtcc aagcgacctt aactggcgat aagaaagttg tcagcattga tttcaatcca
     2701 gctgtcgttg acccagagga ccttgagact ctttctgata tgaccgttca agccatcaac
     2761 tctgctcttg aacaaatcga tgaaactact aagaaaaaac tgggtgcttt cgctgggaaa
     2821 ttgccattct aaaaacaagg agctagaaca atacttgtcg ataacaaagg ctaagaaagg
     2881 tgcaaaaatt ataaaaaacg catagtatca agcaacctaa aactttgggc tctataatat
     2941 ttgtagtggg taaatccact atagatatta tggagcctat tttattgtag aaaaaaatcc
     3001 cataagatct ataatgaaaa gcgaccaaac aactcattag aaagattcat atgggacaat
     3061 tacattttat cacaaaatta ctagacatta aagaccctaa tatccagatt ttagacatca
     3121 tcaataagga tacacacaag gaaatcatcg ccaaactgga ctacgacgcc ccatcttgcc
     3181 ctgagtgcgg aagtcaaatg aagaaatatg actttcaaaa accgtctaag attccttacc
     3241 ttgagacaac tggtatgcct actagaatcc tccttagaaa gcgtcgattc aagtgctatc
     3301 actgttcaaa aatgatggtc gctgaaactt ctatcgtcaa gaagaatcac caaatccctc
     3361 gtatcatcaa ccaaaagatt gctcaaaagt taattgaaaa gatttctatg actgatattg
     3421 cccatcagct ttccatctca acttcaactg ttattcgtaa gctcaatgat tttcactttg
     3481 agcatgattt ttcgcgtctt cctgagatta tgtcttggga cgttgaaaca gtccggggag
     3541 tgactgtttc aatcgggaga tggagatgag ctttattgct caggactttg ataagctcaa
     3601 tatcataact gttcttgaga gcagaacaca agccatcatc cgaaatccca tgaatacaag
     3661 gctatcaagc gctactggaa actcattcaa caggatagcc gtaaactgag tgataagcga
     3721 ttttatcgtc ctacttttcg tatgcattta accaataaag agattttaga caagcttttg
     3781 agctattcac aagacttgaa acatcactat cagctctatc aactcttgct gtttcacttt
     3841 cagaataagg aaccggagaa atttttcgga ctcattgagg acaatctaaa gcaggttcat
     3901 cctctttttc agactgtctt taaaaccttt ctaaaggaca aagagaaaat cgtcaacgcc
     3961 cttcaactac cctattcaaa cgccaaattg gaagcgacca ataatctcat caaacttatc
     4021 aagcgcaatg cctttggttt tcggaacttt gaaaacttca aaaaacggat ttttaccgct
     4081 ctgaatatca aaaaagaaag gacaaaattt gtcctttctc gagcttagct tttcttcaac
     4141 ccactacagt tgacaaagag ccagaaaacg cataatagca ggtgtcaaga cacttaatat
     4201 tatgcgtttt ctcatgaaaa aattctcttt tcatactcat ttaaaatcaa aaagggaaat
     4261 tatcgtttta cggacataca tattacagat ttctataggt cgtgtataga caggatatca
     4321 tcgcttggaa gttttccttt ttgacaccaa tcagtaattt agttctcagg aattaatggc
     4381 agtgcttttc gtacatagtt tcataactac agtatagcat agtatatcgc tttatagttt
     4441 tcactattga tgaactgctt gagctgctgt gatgagggtc aacttgtaaa catcatctgc
     4501 attacatcca cgagaaagat cattaactgg cttgtttaaa ccttgcaaaa caggtcctac
     4561 agccgcaaag ccacccaggc gttcagccat cttgtaaccg atatttccgg cctcgatacc
     4621 tgggaagatg aagacatttg cttgaccagc taccgtactt ccaggagctt tcagagctgc
     4681 agtttcagga acaaaggctg catcaaattg caactcacca tcgatttcaa ggtcaggacg
     4741 caagtcgtga gcaattttag ttgcttcaac gaccttatca acgctttcac caaaccctga
     4801 acctttagta gaatagctca acatggcaat tttaggttcg atgccaaaca tcttagctgt
     4861 gattgctgag ttgatggcaa tttcagccaa ggcttctgca tctggattga tgttaatggc
     4921 acagtctcca aataggtaac gttccgtacc acgaaccatg aggaaggctc ctgaagtacg
     4981 agttacattt ggacgagttt tgatgatttg tagagctgga cgaactgttg aagctgttga
     5041 gtgaatcgct cctgacacca ttccatcaac caagcccaag taaaccaaca tcacaccaaa
     5101 gtagttgaca tcttcaacca aaaccttgcg tacatcttct tcagtcattt tgcccttgcg
     5161 acgctccacc aaggcagaaa ccatttcttc aaattgagga taatgttgag ggtcgatgac
     5221 ctcataacca tccatgattc cttcaatttc aagataaatt ttaatttttt caggatttcc
     5281 aagcaaaaca ggaatcactt ctgtttcttt tactaagcgt tttgttgctt gaagaatacg
     5341 aggctcttcc ccttcaggga gaacgatacg agcattttta ccaacaaggt tggctttgag
     5401 actttcaaaa acttccatga gttttctcct ttaagataat aattatactc tgagacagtt
     5461 tttatagagt attagttgat aactgggtaa taaggttact gaaatcatcc ggcaagggac
     5521 tttctaactg caagtcttgc tctaaaaatg gatgataaaa ggataggtaa tggcaatgca
     5581 gagcctgacg ttgaatacca tcttccagac taccaccata caaatcatct cccagcaaag
     5641 gaaaaccgat atgagaaaaa tggactcgga tttgatgggt tcgaccagtg tgcaggtgaa
     5701 tatagaccaa gtgaatattt ccataagaag ctacaatctt gtatgaagta tgggcatact
     5761 ttccgccttt agccactcgt ctggtaataa tggaatcttc atcacgcgca atcggagcaa
     5821 taatttcccc ttctggctcc aaatgtccat ctcccttaac caaagcaaag tagcgtttct
     5881 cgatagattt cttctgcaac tgcttgtcta atcgtgcatg ggcataaccg tgcttggcaa
     5941 agagcatcaa gccagaagtg tccctatcta gtctggtaac aatgtgaacc tgctgatttt
     6001 cataattttg cttgacatag taacccttga taaaattggc aatggtgtta gagtgattga
     6061 cactaggaat agaagccact ccatagggtt tattcaagac tagaaagtgg tcatcctcat
     6121 agagaatatc taatggatgc tcaatagcct ccaaggtttc aaagccttcc tcagcgggaa
     6181 tgtcaatggt aacgtagtct ccaacgtcca atagatacgt tgcattttgc ggttgattat
     6241 tgaccagaat agctccacct cgaaacttaa tcttagccag caatccctta gaaacctcgt
     6301 gcttttttaa aaaggtctta accttgacat gttcatctgc gataaattca aacctcattc
     6361 atccacctca ccgataaagg catccttaac acggttccag aaactggtat ggctaggagt
     6421 cgcgacaaag tgaatcttat gatggtcgat ttgatactca atacgctcaa tattacggaa
     6481 agaataaacg ctattgtcaa ccgaaatagt atgataatcg tttcttgttg gaataagttc
     6541 aatcttatcc ttcttaggca caataatgga agagcccagt gttcgataaa cacgattatt
     6601 aaggctggca atttccgtta attgcaaagc ttcaatggta gggtgtaaaa cagcaccgcc
     6661 aagagacttg ttataggcag tactaccagt cggtgtcgaa actgttagcc cgtctccacg
     6721 aaaacgttca aagggaacac catttattac aatatctgcc accatggttc gatcagacct
     6781 gcggatgctg gcttcgttga gtgctctgaa aatcttaact tcaccatttt caagaaagac
     6841 cttcacattc agaacagggt aagaaaccct tgccccagta tctagctgca aattagtcac
     6901 tagcttgtcc aactcaaaat cacgataatc tgtatagaag cccaaatgtc cagtatgaag
     6961 accgataaag cggaccttgt caagctgatt ttcgtactta tgaaaggccg acaagagcat
     7021 accatccccg ccaatggaaa tgacaatatc cggattggta tcattgagta taaactgatt
     7081 tctcttcaaa cgatctcgca attcatacaa aaccctttga ctctgcggtt ttctattggc
     7141 tatcagatca attcgtttac ctgtattctt catctgtatc gtcactgttt cctacaccgt
     7201 catttaattt tctactcaaa ggatcaaaaa gtgcctgggc ttcttggata tcatcacgaa
     7261 tttcacccat ttcttcatcc aactgatggg cgattctagc tgtaatttcc agtcgcttct
     7321 taatctcatc tgggaaatcc ccttggtact tgtagttgag agaatgttct atcgttgccc
     7381 agaaattcat ggccaaagta cgaatttgaa tttctgccaa aatagtctta gctccattga
     7441 tggtatcaac cgtatattct actaccacat gataggaacg atagcctgat gcttttctat
     7501 gagtaatgta atctcgctcc tgtatgattc gcatatcctg acgcttgtgc aaaatatcca
     7561 ctacttcctt gacgtcatct acaaactgaa ccatcacacg taagccagca atatcctgca
     7621 aatcgtgttc caaggtcgca taagtaatgc cacgacgagc cattttttct ttgatgctct
     7681 caattggctt gactcgaccg gtcacaaact caattggaga atgcttattt tgcttacgat
     7741 attgcttacg aataccacga agtttaatct ttaactcacc aacagcttga atgtaaggat
     7801 ctagaaattc ttcccattct aaggtcatat attctccctt gttctcatat tatccgtcaa
     7861 aaatatcttt gattttttct ccagattcat atacaataaa tacaatgctt attataccat
     7921 aaatccgctt tcaacgataa aaaaaggtaa gaaaaatgaa acatttagaa attgaattga
     7981 aaacactatt gaaaaaagat gaatacaatc gtctaaaaga ccagttcaca ggtgtcactc
     8041 ctgttcttca aacaaattac tacatcgaca cgcctgattt tgaactgcga gaaaagaaag
     8101 tcgctatgcg cattcgaacc tttgaagact gggctgagtt gacactcaaa gtcccgcaga
     8161 gtgttggaaa catggaatac aaccaaaaat tgcaactaaa agatgctgag gactatctga
     8221 gtaaggaaga acttcctcaa ggactagtac tggatgaatt ggcgaaacat ggtatccaaa
     8281 gtaagaactg gcaggttctt ggttgtctaa caacgcttcg ctatgaaatg aaaacagcta
     8341 ttggtctcat ggcactggat cagagccgat actttgatat aacagattac gaattggagc
     8401 ttgaagtgga aaatcatgag caaggcaaac aggatttccg acaattttta gagaaaaatc
     8461 agatttccta ccaaaaagct ccttcaaaat tggttcgatt tgtcaaaagt atgaaaaata
     8521 gctgaaataa tctccatttt ttggtaaaat agaaaagata aaaatacaca aatcccagtt
     8581 catatatgta aggtaaatat aactaggatt tataaagttt acagaggacg gtctataatg
     8641 tcagatagaa aaaacatgaa acttttcgca ctcaactcta accaagagat tgcacaaaaa
     8701 attgcccaag ctgttggtgt cccacttgga aaactatcat cacgtcaatt ttcagacgga
     8761 gaaatccaag taaatatcga agaaagtgtc cgtggttatg atgtttacat catccaatca
     8821 acaagtttcc ctgtcaacaa ccacctaatg gaattgttaa tcatggtcga tgcttgtgtg
     8881 cgtgcaagtg cccacagtat caacgttgtc cttccatatt ttggctatgc acgtcaagac
     8941 cgcattgctt gtcctcgtga gccacttaca gcaaaactag ttgccaatat gctggttaag
     9001 gctggagttg atcgtatcct gactcttgat ttgcatgccg ttcaggttca aggtttcttt
     9061 gatattccag tggataatct tttcactgtt cccctattcg caaaacatta ctgcgataaa
     9121 ggattgcttg gttcagatgt tgttgtcgtt agccctaaaa attcaggtgt caaacgtgcg
     9181 cgtagcctgg ctgaatatct tgatgctcct atcgccatta tcgactaccc tcaagacgat
     9241 gcaactcgta acgaaggtta tattattggt gatgttgaag gtaagaaagc tatcttgatt
     9301 gatgatattt taaatacagg acgtaccttc tctgaagctt ctaaaatcgt tgaacgtgaa
     9361 ggagctacag aaatttatgc tgtttctagc cacggtctct tcgtcgaggg agctgctgag
     9421 cttcttgaca atactaatat taaagaaatt cttgtgactg attcagtagc aacaaaagaa
     9481 aaaactccta aaaatgtatg ctacatcact gctagtgagt taattggtga tgctatcgtc
     9541 cgtattcacg aaagaaaacc agtcagccca ctctttgcct acaataaaaa gaaataaggt
     9601 gattctttga tttatttgga caatgctgca acgactccta tgtcagcagt tgctatttca
     9661 gctatgacca aggttatgca agaaacccac ggaaatcctt ctagtattca tggtcatggt
     9721 cgtcaagctg gcaaactctt gcgagaagcc cgtcaggaac tagcccagtt actaaggaca
     9781 aaacctcaac atatcttttt cacttctggt gggactgaag gcaataatac taccatcatt
     9841 ggctactgtc ttcgtcacca agaacaagga aaacatatca tcacaactgc catcgagcac
     9901 catgctgtcc ttgaaacaat tgattacttg gttcaacact ttgggtttga agcaaccatt
     9961 atccagccag aaaatcaaga aatcacagcc cagcaaattc aaaaggcttt acgtgacgat
    10021 acgattttgg tttctaccat gtttgccaat aatgagacag gaaacctact gcccatcgct
    10081 gaaattggcc aaatactcaa gcaacaccct gctgcctatc atgttgatgc agttcaggct
    10141 attggtaaaa tcccaattca ttcagaagaa ttgggcattg attttctcac tgcttctgcc
    10201 cacaaattcc atggtcctaa gggaatcggt tttctctacg catctagcat ggactttgat
    10261 tcctatctac atggcggaga ccaggaacag aaaaaacgtg caggaactga aaatctgcct
    10321 gctatcgtag gcatggttgc agccctaaaa gaagacctag aaaaacaaga agaacatttt
    10381 caacatgtac aaaatctaga aaccgccttt ctggcagagc tggagggcat tcagtattac
    10441 ctgaatagag gaaaacatca tctcccttat gttctcaata ttggatttcc tggtcagaaa
    10501 aatgacctct tactccttcg gctagattta gctggaattt caatctctac tggctcagcc
    10561 tgtactgcag gcgttgtcca atccagccat gttcttgaag ccatgtatgg cgcaaattca
    10621 gaacgcttga aggaatccct tcgcatcagt ttgtcgccac aaaataccgt tgaagaccta
    10681 caaaccctcg caaaaacctt aaaagaaatt atcggaggtt agccatatgg catttgaaaa
    10741 aatcattcag ttaaaaaatt gtcgttacga ttacactctt agcccttctg ttaaaaaatt
    10801 caccctcaaa gataacacct tttttgaaac taaggttggt aactatgaac tgactcgcct
    10861 tttggaaaaa gtgccaaaca gcggtgaagg cttccaactc aaaatcatca ttaacaagga
    10921 acttacaggg gctaaaatca atatcactga caagtttagc cttcgtctag ttgatatttt
    10981 caaatcagaa gaccaccata ttcatcagga aaaattctac ttcctcatgg atagcttggt
    11041 agaacgtggt gtctttacaa aatcggaaag atagagccaa aatgtttgaa ctgacctata
    11101 aggactgcta tcatgtagag cgtactctca agtatgagga tcatgaggct ctcatgttga
    11161 ctttgtcagg atgtgtaacc ttaccagata cactttatgt gacttctctg acttttaggg
    11221 gccaaaaagt ttatcagggt ctggtcggag acctctaccg ttttctatct catgcagatt
    11281 ttttacatca aaactaagat ttttcttagt tttttcttat ttttgttgat tttttcacaa
    11341 tgtttctata aaatagaaga atagaaaggt tgtgattttg tgaaagataa acagtttgct
    11401 attccaaaag ctacagcaaa aagactctct ctctactatc gaatttttaa gagatttcat
    11461 gcagaaaaga ttgaacgtgc caactctaag caaattgcag aggctatcgg tattgattca
    11521 gcgaccgtac gtcgtgattt ttcctatttt ggtgaacttg gtcgtcgtgg ttttggctat
    11581 gatgtcaaaa aactaatgac attttttgcc gatttgctca atgacaactc tattaccaat
    11641 gtcatgctgg ttggtattgg aaatatgggc catgcccttc tccactaccg cttccacgaa
    11701 cgtaacaaga tgaagattat catggccttt gacctagacg accatcctga agtcggtacc
    11761 caaactcctg acgggattcc catttacggg atttctcaga tcaaggataa aatcaaggat
    11821 gctgatgtga agactgctat cctaactgtt cccagcgtca agtcacaaga ggttgctaat
    11881 ctcttggttg atgctggtgt gaaaggaatt ctcagttttt caccagtcca tctgcattta
    11941 ccaaaagacg tggtcgttca gtatgtcgat ttgacaagtg aactccaaac cctcctctac
    12001 ttcatgcgaa aagaggatta gaaagcgaaa atcattttat gaaaaaacca gttattggga
    12061 ttacaggaaa cgaaaaagct catccagatg atgacatcat gatgagctac gcagcaaaag
    12121 gctttgttga aggcgttaaa gatgctggag ggattcccat catcctaccg attggtgatc
    12181 aagaaatggc ctgccactat atcagtttga ttgacaagct catcttgaca ggtgggcaaa
    12241 atgtcgatcc aaaattttat ggcgaaccca aaaccattga tagcgatgac tataaccttc
    12301 aaagagatat cttcgaactg gccctcatca aggaagctat taaacagaaa aagcccattt
    12361 tctctgtctg ccgtggtacc caactcttta acgttgccat gggtggaact ttgtaccaag
    12421 atatcgaaga ccattggcag gattcttctg ttgagtacac aactcaacgc ttggtaacag
    12481 aaccagatac cgttctccaa gaaatctatg gagaaatctc tcatatcaac tccttccacc
    12541 accagagcat caaggactta gcaccaaatt taaaagttgt ggctcatgat cctaaagatg
    12601 gtatcattga ggctgtcatg agtacggatg atgtcgcctt tctcggtgtc caatggcatc
    12661 cagaacttct ttttgaaaat cgtcccaaag ataaaaaact ctttgactat gtcgttaatg
    12721 aactttagat taaatctgtc ttttcacgat aactaaagta attagaatga gagacaatca
    12781 aatggtccaa gagaacaatc cccatcaatt cgcaggcttc tttaacaagt ttagtgacat
    12841 gatcatcatt ttggctaggc gctaccgctc ctgaaggatg attgtggacc aagataagag
    12901 aagtcgccat atgcttgatt gcatagtgaa gaatctctcg cggttcagcg atactacgag
    12961 ttacagaacc gataaaaatg gtctgctgat ggatgatttg attttgagta ttgagataga
    13021 gtgccaccag gtgctcttgt tttttatccc ctaattcctg ctgcatcttc ttggccaact
    13081 tttgactgct gagaatactt tccatttcaa gagtctcgtg tttgtgaata cgatgcccca
    13141 gttcaatcat agcttgtaat tctatggcct taacacgccc aataccagac aaactctgca
    13201 attcctgcag ggtcattttt ttcaaatccg ttaggcttga aagattgttc aagacttttt
    13261 gggcaatttc aaaaacgcta gcttgacgtg ttcctgtcct gagtaaaata gctagcaact
    13321 cttggttact aagcgcttca actccttcct tggccagcct ttctcttggt aatagtgaat
    13381 cttcttggaa tgaaatactg tacataaaaa tcctcctcac tttattattc gtgagaagga
    13441 tggaaaatta gatttttttc tcaattggag ccacactggc taaaagtttt ttcaaaccta
    13501 cttctgggaa attgattttc aattcctgcc tagcaccgct acctgaaact tccagaacag
    13561 ttccctctcc ccatttcttg tggagagcaa tgtcaccaat ggaccaattt gcctcgctag
    13621 atgctgattt tgcgccagct gtaaattgac caaatggaag accgcttgac tggatcgatt
    13681 ttggggcagc accgcgttta cggtcttgaa gagcctgagc caaactcata ccttgaccaa
    13741 aggaaatact accactgcta tatgatgcct taaagcttgt atttgcagga cgagccagac
    13801 cttgatactc aagcaagtct gaactgattt cgttaataaa acgagtcgga cggttataat
    13861 tggtacgacc aaaaagcaag cgtgagttgg cattggtcag atagagaatt ttctctgcac
    13921 gcgtgatacc tacataggct agacggcgct cttcttctaa ttcatctgga tcttcagtcg
    13981 cacgactaag tggaaagaca ttttcttcca tcccaatcaa aaagacaact ggaaattcga
    14041 gacctttggc agcatgcagg gtcatcaagg tcacttctga tgtctcctga ctacctgaat
    14101 ctgtgtcggc aatcaaagcc aagtcattta agaaacgact cagtttgtcc agaccagttt
    14161 cctcttctgt cacatcagtg gtgtcatcaa agttcttcgt aacagaaaga aactcttcga
    14221 tattttcaac ccttgccttg ctttctagag tcgcttgggc gttaagaata tcgacataac
    14281 ctgttttttc taggacggac tcaaccaact ctgtaatgct taagtggtct agctgctccc
    14341 gcaaatcaag catcatattg gcaaaatccc agatagattg ggctgcctta cccttgatac
    14401 cagacaacat aatattagca gaagcatcca gcatagacat attttgcaaa tttgcaaaat
    14461 cacggatttt ctcaactgta cctagaccaa ttccacgttt aggctcgttg ataatacgct
    14521 caaaactaat gttgtcactc aaattagcaa taaggttgag ataagcaata atatcgcgaa
    14581 tttccttacg gctgtagaat ttggttccgc caaccatggt ataaggaatg ttagacttga
    14641 gcagggcttc ctcaattgta cgggactggg cattagtccg atagagaact gcaaaatcct
    14701 tatgaaggaa gttttgactg cgactaagtt catcgatggt tctggctaca aatacagcct
    14761 catccagctc atcatcagca cgatagtaaa cgatttgctc cccatcagcg ttttgagtcc
    14821 agagattttt aggacggcga tttttattat ttttaataac ctcgttggcc gcttggagaa
    14881 tggttttggt tgagcggtaa ttttcctcca acaaaacaac cttagctttg gggtaatcct
    14941 tttcaaagtc caagatattc tgcatatcag caccacgcca accgtagata gactggtccg
    15001 catccccaac cacacagata tttttaaaac gggaagccaa gagtttgacc aattggtact
    15061 gagcgtggtt ggtatcttgg tactcatcaa cgtggatgta ttggaatttt tgctggtagt
    15121 aggtcaaaac atcaggattt tgatcaaaga gacgcaaggt cagcataatc aaatcatcaa
    15181 agtcaacgga ttcagactga cgaagttctt tttgataggt tgtataacac tgggccacaa
    15241 tttgcgtata catatcgcca gcttgagcag cataagcaac atcatcaatc aaatcattct
    15301 tagcattgga aatggtcccc aaaatagttc gttcattcca ttttttagga tccaagttca
    15361 actgtttgag aatacgtttc atgagcgttc gctgttcacc aggatccaca attgtaaaat
    15421 tacgattgta gccaatatgg tccgcatcgc gacgcaaaat acgcacacac atggagtgga
    15481 aggtcgcaat cagacagtcc tgagtagctg gattgaggct ataagcacgc tctttcatct
    15541 cacgcgcagc cttgttggta aaggtaatgg ccaagatatt ccaaggattg accagctttt
    15601 catcaatcaa ataagcgata cggtgggtta aaacacgagt ctttccagaa ccagctcctg
    15661 ccatgattag caagggacct tctgtcgttt gcaccgcctc agcctgacgg tcattcattc
    15721 catttaataa tgcgttcatc ttctcttcct tactcttgaa gtcaatattt ctattatatc
    15781 agaaatcagg gaaaatagaa actttacggg gagtagcaaa atatagtgga ttgaaactag
    15841 aatactacac tgtgggtttc taaaacactc gactttttca cccaattttt tcataaacta
    15901 gctcaatacc tcaatagact tcctgcaaaa ctagaatcct agttcat
//
LOCUS       DBERAE010000047        15258 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.47, whole genome shotgun sequence.
ACCESSION   DBERAE010000047 DBERAE010000000
VERSION     DBERAE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.47"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            83..880
                     /locus_tag="ACL70N_001805"
     CDS             83..880
                     /locus_tag="ACL70N_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGS0590560.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="ACL70N_001806"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="ACL70N_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2383..3657
                     /locus_tag="ACL70N_001807"
     CDS             2383..3657
                     /locus_tag="ACL70N_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGS0590561.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="ACL70N_001808"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="ACL70N_001808"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGS0590562.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="ACL70N_001809"
     CDS             4786..5088
                     /locus_tag="ACL70N_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS0590563.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="ACL70N_001810"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="ACL70N_001810"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS0590564.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /gene="xseA"
                     /locus_tag="ACL70N_001811"
     CDS             5962..7302
                     /gene="xseA"
                     /locus_tag="ACL70N_001811"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGS0590565.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="ACL70N_001812"
     CDS             7280..7492
                     /locus_tag="ACL70N_001812"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGS0590566.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="ACL70N_001813"
     CDS             7489..8364
                     /locus_tag="ACL70N_001813"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGS0590567.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="ACL70N_001814"
     CDS             8357..9172
                     /locus_tag="ACL70N_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGS0590568.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="ACL70N_001815"
     CDS             9165..9596
                     /locus_tag="ACL70N_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0590569.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="ACL70N_001816"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="ACL70N_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGS0590570.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDMTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="ACL70N_001817"
     CDS             11272..12000
                     /locus_tag="ACL70N_001817"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0590571.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="ACL70N_001818"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="ACL70N_001818"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGS0590572.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13983..14180)
                     /locus_tag="ACL70N_001819"
     CDS             complement(13983..14180)
                     /locus_tag="ACL70N_001819"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590573.1"
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATMTWFEEIFEEYKN"
     gene            14359..14835
                     /locus_tag="ACL70N_001820"
     CDS             14359..14835
                     /locus_tag="ACL70N_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0590574.1"
                     /translation="MVLDYFFDKNLVLCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMNFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
     gene            14873..15175
                     /locus_tag="ACL70N_001821"
     CDS             14873..15175
                     /locus_tag="ACL70N_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590575.1"
                     /translation="MIKILAACGAGVNSSHQIKSTLEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSAPVFDNIRLPAKQNMV"
BASE COUNT         4561 a         2767 c         3569 g         4361 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aaacttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ttgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccttca
     2341 tgcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gcggagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaaca ccaatcggtc
     4921 atggccgatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagat caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagattaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgcctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgctaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattttt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatatgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tctcaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatggag aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 gggattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggttttc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc aacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgct ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcatcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14101 tcgtcagtct tatctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaag agacaaaaaa
    14281 gaacagaaag taattaacaa cgatttcata tagtgttata cttatggcat aaagttaatg
    14341 gaaagaaggg aaaaccttat ggtattagat tatttctttg acaaaaacct tgtgctttgc
    14401 ttagaagcgg ataatcaaga acaactcttt gatcaggtag caagcttgtt ggaagaacga
    14461 gaaattgtca ctcctactta tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact
    14521 ggtttagata tggaatttct aggaaaggac ttgccaaatg tagcgattcc tcacacagat
    14581 attgttcata atctagctga gaaagtggtg gttgttcgat tagaaaaacc agtaactttt
    14641 cacaatatga tagctcccga taaggaagta gaagtatccc tactcttctt tatcattaat
    14701 aattcaagtt caagtcaaac gaacattctt gctcagttga tgaacttctt cacaggaaat
    14761 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttatatagat
    14821 gaagcaatcg cttaatcttg tctattaaaa aataaaatcg gaggaagtct atatgattaa
    14881 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtactctaga
    14941 agaagaactt tcaaaccgtg gttacgatgt tcactgtgat gcagtcatgg tgaaagatgt
    15001 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagatcttgg
    15061 ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattttgta tcccagcaat
    15121 gagcgctcca gtatttgaca atattagact ccctgcgaaa caaaatatgg tatagtagtt
    15181 ctatgaatga tgaagcaagt aaacaactaa ccgatgcacg atttaagcgt cttgttggtg
    15241 ttcagcgtac cacttttg
//
LOCUS       DBERAE010000048        14992 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.48, whole genome shotgun sequence.
ACCESSION   DBERAE010000048 DBERAE010000000
VERSION     DBERAE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.48"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..173)
                     /locus_tag="ACL70N_001822"
                     /pseudo
     CDS             complement(1..173)
                     /locus_tag="ACL70N_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(522..914)
                     /gene="rpsI"
                     /locus_tag="ACL70N_001823"
     CDS             complement(522..914)
                     /gene="rpsI"
                     /locus_tag="ACL70N_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGS0590576.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(934..1380)
                     /gene="rplM"
                     /locus_tag="ACL70N_001824"
     CDS             complement(934..1380)
                     /gene="rplM"
                     /locus_tag="ACL70N_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGS0590577.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1736..2053
                     /locus_tag="ACL70N_001825"
     CDS             1736..2053
                     /locus_tag="ACL70N_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGS0590578.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(2098..2910)
                     /gene="folK"
                     /locus_tag="ACL70N_001826"
     CDS             complement(2098..2910)
                     /gene="folK"
                     /locus_tag="ACL70N_001826"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGS0590579.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2953..3507)
                     /gene="folE"
                     /locus_tag="ACL70N_001827"
     CDS             complement(2953..3507)
                     /gene="folE"
                     /locus_tag="ACL70N_001827"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGS0590580.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3488..4810)
                     /locus_tag="ACL70N_001828"
     CDS             complement(3488..4810)
                     /locus_tag="ACL70N_001828"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS0590581.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGMFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4812..5786)
                     /gene="folP"
                     /locus_tag="ACL70N_001829"
     CDS             complement(4812..5786)
                     /gene="folP"
                     /locus_tag="ACL70N_001829"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGS0590582.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVAIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5881..6588)
                     /locus_tag="ACL70N_001830"
     CDS             complement(5881..6588)
                     /locus_tag="ACL70N_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0590583.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLVLFIMGARKTKLASFNFSFFRAKDLARLVLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIIPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6642..8060)
                     /locus_tag="ACL70N_001831"
     CDS             complement(6642..8060)
                     /locus_tag="ACL70N_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGS0590584.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            8250..9062
                     /locus_tag="ACL70N_001832"
     CDS             8250..9062
                     /locus_tag="ACL70N_001832"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0590585.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9401..10420
                     /gene="adhP"
                     /locus_tag="ACL70N_001833"
     CDS             9401..10420
                     /gene="adhP"
                     /locus_tag="ACL70N_001833"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGS0590586.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10653..11642
                     /locus_tag="ACL70N_001834"
     CDS             10653..11642
                     /locus_tag="ACL70N_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590587.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11670..12473
                     /locus_tag="ACL70N_001835"
     CDS             11670..12473
                     /locus_tag="ACL70N_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGS0590588.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12497..13408
                     /locus_tag="ACL70N_001836"
     CDS             12497..13408
                     /locus_tag="ACL70N_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0590589.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13464..14798)
                     /gene="pepC"
                     /locus_tag="ACL70N_001837"
     CDS             complement(13464..14798)
                     /gene="pepC"
                     /locus_tag="ACL70N_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGS0590590.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT         4330 a         3335 c         2969 g         4358 t
ORIGIN      
        1 aaggtattgc aacttggtaa tacctttttg aggtgctttt tgatatgagc ccatgttttc
       61 tcaataggat tgtactcagg tgagtaggga ggaagaggta aaagtttata cccaaactct
      121 tcacacaaga gttctagctt ccccattcta tggaatcttg cattatccat aatatagtag
      181 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg atttgactat
      241 cctcgatttg tcctattctt atttcatatt actataaaaa taaggtaaac ttttcaaaaa
      301 agcacgaaaa aagcacccat agggcaaacc tttgagtgct ttgaaacatt gatataatcg
      361 tattgattaa cgttttgagg caactgacct tgtcaggttg cagccacatt tgtaagcgac
      421 taaagtcgca acaactgtgt caattgcacc aatttagtaa gaaagtataa aaaaagaaca
      481 ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt actaaattgt
      541 gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg tgagtcacgt
      601 gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg aagaagggca
      661 cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc tacaacgtta
      721 acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt gatgacaaga
      781 cgaaggtcag cgtgtgggat atactcttca acatcttttt tgttaacagt gattttacca
      841 gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt acctgcatat
      901 tgtgcttgtg acatacttta tttgttcctt tccttagata agtcctgaaa tgtcaagaac
      961 ttctggttgt tgtgcagcat gagtgtgctc agctccaaca aatactttca acttcatacc
     1021 ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct caatcaaacg
     1081 tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac ctgggtggtt
     1141 tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa ctttttcagc
     1201 attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg gtttgttttt
     1261 tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat cagttgcgtc
     1321 aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg ttttgttcat
     1381 gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct tcccatcgaa
     1441 aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc tactatcata
     1501 ccaaatttca cccctaaaag tcaatagata taaaaaatat ttttcggtaa cttctcaaaa
     1561 taactgaaag ttatataatc aagttaattt gggaatttac ctattaactt cggtagattt
     1621 ttgggaattt tttccctatt tctccctgta actaaaatcc ttttcaaaaa atcacctttt
     1681 cttgattttt aatcctattt gctgtatgat aagggaaaag aaaggggaca gagatatggc
     1741 ttttaccaat acccacatgc ggtctgctag ttttggcatt gttaccagct tgcccgatga
     1801 catcattgac tctttttggt atatcatcga tcatttctta aaaaatgtct ttgaattgga
     1861 agaagaactc gagtttcaat tgcttaataa ccaaggaaag attaccttcc acttttcaag
     1921 tcaacacctc cctacagcca ttgattttga ctttaaccat cctttcgacc ctcgttatcc
     1981 cccaagagta ctggttttag acatggacgg tagagaaact atcctcctcc cagaagaaaa
     2041 tgacctattt taaaaactct agccttcagt tgcaagtaac tgaaaactag agtttttcta
     2101 ttttttcaaa gcatcataca agttgcggat cggttgtttt aatatcggat ggataaaatg
     2161 aggcgcaatt tcctgtaagg actcaaggac aaaaaggcgt tccgctatgt aaggatgagg
     2221 caatatgagg tcgtctgtat aaaggatctg gtcctccaca aagagcaagt ccaaatcaat
     2281 caaacgaggt ccccaatgca cttctctcac ccgtcccagc tctgactcaa tggctaacaa
     2341 ggtttctaac aagtcttgtg ctggtagcca ggtttccacc tcaaccactt gattggcaaa
     2401 gctatcctgc tccactccac cccaaggctc cgtcgctaag acactggact ctttgagaat
     2461 atggatacct cgatttcgca ttttctcaat ggcttgtttc aagtttgctt gtttatctcc
     2521 catattgctt cctagggcga taaaggctcg ttgcttgcgg cgatggatgg ttaccgagca
     2581 agtatctagt gacaaatgca ccggtgccca aggttttttc agttccaact tcatttcttg
     2641 gacaagagga taagactcaa aggtacgttc caccagttta taggctaccg tttcaatcaa
     2701 atcttcactc gtttcctgaa accaagtcgt ccactgctga cacaattctc cgtaatggac
     2761 agaggctgtt aaatccaagt ctgtagctgc cttggtcata tcataggata ggatggctga
     2821 aacgacaaat ttctgcccca attctttctc actaggaaaa agaccatgat aggcaaacat
     2881 ttccaaatcc ttaatctgca gttgatccat aatgattcct ttctagaaaa atccgcttga
     2941 agcggattct ttttatagcc ccattaaacg ataagcttgg tcgcggaggt ccttatctgt
     3001 ttcaaataga ccacgagcta ctgtcgtcaa ggttgcagtg cctggttttc taacaccacg
     3061 catactcata cacatatgtt ccgcctcaat gacaacaaag gctcctttag cacctagata
     3121 gtccatcaag gcatcggcca cttcgatatt caaacgttct tgaatttgtg gttttttcga
     3181 ataaacttca accgtacggg ctagcttaga caagcctgcc acacgaccat ctggaatgta
     3241 ggcaatgtgc gctctaccat aaaatggcaa gaagtggtgt tcacacatgg tatggaaaaa
     3301 gatatccttt tctaccacca tattatcgtc aataatttca aaggattttg acaaatgttc
     3361 ctctgctgtt tgaccaagac ctgaaaaaat ctcttgatac atacgggcta cacgagcagg
     3421 tgtttcctgc aagccctcgc gattagcgtt ctctcctaca gcctcgataa tcatttttac
     3481 agctgcttca atcttttgtg tatccattct cgttcttcct ctccatcaga taggccctca
     3541 cttggctcaa gaaatacaag gaacctgtga caatcctaac tgtttgtttc tcttcttttt
     3601 tatctgtcac attctgctct agaaaatcat gccaatcttg gtagctgaga tttctagact
     3661 tagctgcctc tttcagcacg ctttcatccg tcgcccgact atccgcaaaa tgtgttagag
     3721 taagctcggt atctggcatg gctcccagca agtccaacat atcctccaag gctttggttt
     3781 tgatacaagt gaagaggatt tccttatgat aatccgcaaa acgttcttgc aaggttacca
     3841 acaaggcctt gatagcatgg ggattatggg ctccatccaa aatcatcaag ggatctcttg
     3901 acacgatttc caaacgccct ggccaacttg tttcttccaa ggcttgacca agaaagtcat
     3961 tgcttgctag ctctcgacca tcttcttgac aaaaagtatc aagtaaagct atggccatcc
     4021 cagcattctc tatttggtac aaaccaagca ggctagtctg gaagcgacct tgtctgacag
     4081 cacttgtata gtcaaagact tcccctgtca ccacactttc ttgatgacga acctgataat
     4141 ctgtcccgta ggcaagtctc ggcgcatctt tcccttccgc aatgcggtca atcacagtca
     4201 aggcttctgg agcaatacgc cctgttacca agggcatccc ttgtttgata atacctgcct
     4261 tctgctctgc tatggcctcc aaggtgtcac caagtagggc cacatgatcc aagccaatag
     4321 ttgtaattcc tgtcaaaatg ggctgacaga cattggtact atccaaaagt ccacccatgc
     4381 caacttccat gatggccaca tctacttgct ctgaggcaaa gtagtcatag gccagggctg
     4441 tgataatctc aaactcggtt gtgccctgta aattggcgac cgcttctccc tccagcaaag
     4501 actgatagtc tgccatgaga gcttctagcc tcgcttctga gatcgattcc ccattgatgc
     4561 taatctggtc tgtgtaatga atgagatagg gcgagctaaa catgccaact ctcagcccta
     4621 gcttttctag catctttttc aaaaaagcaa tagtcgagcc cttgccgtta gttcctccga
     4681 tatggaggac cttgagtttg agatggggat tgccacgcaa agctaacagt tccaccattc
     4741 gttccaagcc aaaatgcggt tgatccgtcc ggtagttagc aatccactga ttgttttcaa
     4801 tttctttcat cttatttata ttgttttaaa tctaaatttt ccgcttcatc agccagacga
     4861 atggcagagg caatttcaac tgccatcctg tgactagcta cgtcatgcac gcgcaccact
     4921 tctacaccct gtctcgcagc gatactagtt acatgagccg aagccgtgtc ccgatttcgg
     4981 aaaccaagct ctgtctcagg attgacttca aaaccattct cctctaggat attgatgaca
     5041 aatcgcttgc gcgacactcc gagaaagatt ggatagccct tctgatgtag tttatccagg
     5101 tcccgtaaaa gaagcagatt ttctttcttg gtcagaccaa agccaattcc tggatccaac
     5161 aggatatttt ctggtgcaat accagcttct gccgctctcg ctagtgctcg ttcaaagaaa
     5221 gcctccatca attcttcgat tggcaatgtt tcaaagtcag ctaactcttc ctctgtaaaa
     5281 gcttgaccaa aaccaaaatg agggaagatg agcgagctag ggtgctgagg tcgcgccata
     5341 actgggttaa acatgatggc cacttgcgct ctcgcttcag ctaccacatg agccattttc
     5401 tcatcaccca taagaccagt gatatcattg actagatcgg caccagcagc caaagcagcc
     5461 tctgctactt gactcttcca agtatcaata gagatgagga catcactttc cttgcgaatc
     5521 gctttgatca ctggaacaac acgctggatt tcctcttcta tctcaacata gctactgccc
     5581 ggccgagtcg attctccgcc gatatcgagc atactggctc cttcggctat caatttacga
     5641 gcctgctgga gtgcctgctc aagagcaaaa aattgaccac cgtccgaaaa ggagtctggg
     5701 gttacattga taattccgca aataactgtc tttgcatgat tggctttact tgacatatcg
     5761 gtcactccct caaggatttt catcatatta tttttctatt ttaccataaa aagaaaaaga
     5821 tggacacgat tgcattcatc tttccctagt agaaagaggt cggttcctac ataaaaactt
     5881 ttacacagaa attcctaatg tccgactcat aatcaccaca agagccaaca aacagaaagc
     5941 aatcccatta acaatcatgt gaagcaagat cgacatttcc aaacgttggg tcttgtaggc
     6001 tgtccaagat agaactgtcg acatacctcc ataaatcaat aaagaaggta aattacttgg
     6061 ttgatgcaat aaagcaaaca caatcgtacc gactacaaat cccaagttct ccttgcctcg
     6121 gaaaatcttt ttaggaataa tcccacgaca caagatttcc tcacaaatcg gagcaagcaa
     6181 ggctagcaag aagaagctag aaatcaacga actattctga accatatcat taatctgaga
     6241 ctggttagct gttgtcgtct catttgacag ttgcaacaag atagaaccaa gtatatttga
     6301 cccgacaata actagataac tcaagaccaa acgtgccaaa tctttagctc taaaaaaaga
     6361 aaaattaaaa ctagctaact tggttttacg agctcccata ataaatagca ccagaaccac
     6421 aattgaaagg ccagcaacta tcagccctga ctgtagcagg gctacttctt ttaaagtcaa
     6481 aatagaggta accactaggg gaacctgata taaaaggacg gcaagtaaaa agaccaaaat
     6541 ccagcctgca cgattcaaca attctttcca catatttttc tctttcatca cctatctcct
     6601 tttgtattaa aaaagggggg aaatccccct gggtcattct attataaggc catgctgatg
     6661 tagttaagga taaacaaggc atccaaaatc caaatcatga catgaacatc tttaacttga
     6721 cctttaacaa gcttagtcaa agtgtaagtc aagaaaccaa ctgcaatccc ttgagtgata
     6781 gagtagctga atcccataaa gatagatgtg aagaaggcag gaactgcttc agacatatca
     6841 tcccaatgga tatttttcaa gctaccaagc atcataatcc caacgataat caagattgga
     6901 gctgtagccg ctgttggtac gatcgctaga agtgggctaa agaagcttga aatcgcaaaa
     6961 cagatagcta caaccaaggc tgtcaaacca gtacgtccac ctgcaccgat accagcagca
     7021 gactcaacat aagtcgttac gtttgaagta cctgcaatgg caccgactgt cgttccaatc
     7081 aaatcagagt aaagagcctt atccaatttg gctgattggt gattttcacc atttgtcgct
     7141 acgataccaa ctttttcacc tgtaccgatc aaggtaccaa ttgtgtcaaa aatatctgtc
     7201 aatgagaagg caagaatggc catcagagtt tcaggcaagc gagctgtatc tgaaaccaaa
     7261 gctcccaaac cttctgaacc aagagctgca ccaaagattg tcttcaaatc ttcaaaagct
     7321 gcaccaacat ggttattagc aaaatcgata ctagacaaat caaccaaacc aactgcaata
     7381 gcaagaacag ttgttgtcaa gatagagaga ataattcccc ctttaatccc tttgatgaca
     7441 aagaagatag taatggcaag tcctgcaaga gccactaaaa cagctggatt attaaagctg
     7501 accaatcctg gaactgctga agagtttgct gcaatcgttg cttgagcttt gtcagcccct
     7561 tctcctacaa cagtatagtt gcctggatca atcgtgaatt tcaaaagtcc agcattctta
     7621 atccctacat aggcaaggaa gacaccgata ccagctgaaa tagctgagcg aagagcattg
     7681 ggaatcgatt caatgatcat tttacgaaca tttgtcaagg taataatcaa tgaaataatc
     7741 ccacagatga agaccatagc tagggcttct tgccaagaat aaccaagccc gaatacaact
     7801 gtaaaggtaa agaaggcatt gagtcccata cctggcgctt gggcataagg taagttagca
     7861 taaaaagcca tcatcaaggt acccgctact gcaccaataa tcgtcgctag gaagacgccc
     7921 tgagcaggca ttcctgtttg tgaaagtatt tgtgggttta caaagagaat atagctcatt
     7981 gcaaagaaag ttgttaaacc agcgagaacc tctgtacgaa cgtctgtacc gttctctttt
     8041 agtttaaata atttgtccat catcaatctc cttttaattt ttacgaacaa taatagaatt
     8101 atatcattta ttattcactt tttcaatgtc tttgtttgat ttgtttaaga aattaatcca
     8161 atttcatttt ttgtttggaa tctgcttttc tgcctgcttt ctgttataat agaagacatc
     8221 ttatctgaaa acacactaga aaggtccata tgacgaaaaa aattattgca gttgacctgg
     8281 atggaaccct gctcaactca gacagtcaaa tttctgactt taccaaaaga accatcaaaa
     8341 aagttgctga aaaaggccat caggttatta ttacgacagg tcgcccttac cgtatgtcaa
     8401 aagattttta ccgtgaactg ggcttagaca ctcctatgat taacttcaac ggatccctta
     8461 ctcatttacc agaccaagtt tgggattttg aaaagtgttt gactgtagac aaaaaatatc
     8521 tgctagatat ggttcaacgt tcagaggaca ttcaagccga ttttatcgct ggagaatatc
     8581 gtaaaaaatt ctacattaca aatcccaatg aagaaattgc caatcccaaa ctatttggtg
     8641 tagaagcttt ccagcctgaa gatcaattcc agcctgaatt ggtgaccaag gaccctaact
     8701 gtatcctctt gcagaccaga gccagtgaca aatatgcctt ggcaaaagac atgaacgcct
     8761 tctaccagca tcaactttct atcaatacct ggggaggtcc gctcaatatc cttgaatgta
     8821 ccccaaaagg tgtcaacaag gcctttgctt tggactactt gctcaagata atgaatcgtg
     8881 acaaaaaaga tttgattgcc tttggagatg aacacaatga taccgaaatg ctcgcttttg
     8941 ctgggaaggg ttatgccatg aaaaatgcca atccagagct actcccttat gcagatgagc
     9001 aaatttccct taccaacgac caagatgggg ttgccaaaac cctacaagac ttattcttat
     9061 aacctatact gatactcaat gagaatcaaa gagcaaacta ggaagctagc cgtaggttgc
     9121 tcaaagcact gctttgaggt tgtagatgaa gctgacgtgg tttgaagaga ttttcgaaga
     9181 gtatgaccag cttgcaagct ggtctttgtg ctcttttcac agtctcatca accagttaat
     9241 cgattgttct actttttgtc tccaaaacct tggaaaaggc tttcttttgt gatatacttc
     9301 acatataaat acaagagagc tcgtcacact cgactctgtt gacaaaaaat caatccagtc
     9361 ccgttgtccc tgttctcggt caatatcaag gaggatagct atgaaagctg ttgttgtaaa
     9421 tccagaaagc actggtgttg ctattgaaga aaaagtactc cgtccacttg aaactgggga
     9481 agcacttgta gaagttgaat actgtggcgt ttgccacacc gacctccacg ttgctcatgg
     9541 tgactttggt caagtcccag gacgtgttct tgggcacgaa ggtatcggta tcgttaaaga
     9601 gattgctcca gatgtgaaaa gccttaaagt cggtgaccgc gtcagcgttg cttggttctt
     9661 tgaaggatgt ggcacttgcg aatactgtac aactggtcgc gaaacccttt gccgtacagt
     9721 gaaaaatgct ggctactcag tagacggtgg tatggctgaa caatgtatcg taactgctga
     9781 ctatgctgtc aaagttcctg acggacttga tccagcccaa gcttcttcta tcacatgtgc
     9841 tggagtaaca acctataaag ctatcaaaga agcaaaagtt gaaccaggcc aatgggttgt
     9901 tctttacggt gctggtggac ttggtaacct cgctgttcaa tacgctaaaa aagtattcaa
     9961 tgctcatgtt atcgcagtcg atatcaacaa tgacaaactt gcccttgcaa aagaagtagg
    10021 cgctgacatt gtgattaacg gcctcgaagt tgaagatgta gctggactca ttaaagaaaa
    10081 aactgatgga ggagctcatt cagctgtcgt aactgctgtg tctaaagttg ccttcaacca
    10141 ggctgttgac tccattcgtg ctggtggtcg cgtcgtcgct gttggtcttc cttctgaaat
    10201 gatggaactc agcatcgtta aaacagtcct cgatggaatc caagtcatcg gttctcttgt
    10261 cggaactcgt aaagacttag aagaagcctt ccaatttggt gcagaaggtc tggtagtccc
    10321 agttgttcaa aaacgtccag tagaagatgc tgttgccatt ttcgacgaaa tggaaaaagg
    10381 ccaaatccaa ggacgtatgg tactcgactt cacccactaa tctaatagaa acctatttta
    10441 aaagttggaa gcttcttcca acttttttat attaaatttt aaataagaat tcaagattac
    10501 tcctcaaaaa ctcaacatat caacatacaa aaataaaaat tttttaattt tttatgataa
    10561 atagttgctt tttttatgaa aacggtttat acttaaacag tcttaaagtt ttcttaaatg
    10621 aaaactaaaa caaaaaagga ggaatgacaa taatgagtat cggaatcatt attgcgagcc
    10681 acggcgaatt tgctgcgggt attcatcagt caggatctat gatctttggt gaacaagaaa
    10741 aggttcaagt tgtgaccttt atgccaaatg aaggtcctga tgatctatac gctaagttta
    10801 ataacgctgt tgctgcattt gacgcagaag atgaggttct agttttggct gacctttgga
    10861 gtggttctcc atttaaccaa gctagtcgcg tgatgggaga aaatcctgag cgtaagtttg
    10921 ccatcatcac aggacttaac ttaccgatgt tgattcaagc ctacacagag cgcctcatgg
    10981 acgctgctgc aggtgtagaa aaagtcgctg ctaatatcat taaagaagcc aaggatggca
    11041 tcaaagctct tccagaagag ctaaatccag ttgaagaagt tgcaagcgct gcagctgctc
    11101 cagttgccca agctgctatc ccagaaggaa ctgttatcgg agacggtaaa ttgaaaatca
    11161 atcttgcccg tcttgacaca cgtctacttc acggtcaggt tgcaactgct tggactccag
    11221 attcaaaagc aaatcgtatc atcgttgctt cagataacgt ggctaaagac gaccttcgta
    11281 aagaattgat taaacaagca gctccaggta atgtcaaggc taacgtggtt ccaattcaaa
    11341 aactgattga gatttcaaaa gacccacgtt ttggagaaac acatgccctt atcttgtttg
    11401 aaacacctca agatgccctt cgtgccatcg aaggcggcgt gccaatcaag actcttaacg
    11461 ttggttctat ggctcactca acaggtaaaa cattggtcaa taccgttttg tctatggaca
    11521 aagaagatgt tgcgacattt gaaaaaatgc gtgacttggg tgttgaattt gatgtccgta
    11581 aagtaccaaa tgattctaaa aaagatttgt ttgacttgat taacaaagcc aatgtcaaat
    11641 aagccattat ttatgaaagg attttaaaca tgtctattat ttctatggtt ttagtagtcg
    11701 ttgtagcctt ctttgcaggt cttgaaggca tcctcgacca gttccaattt caccaaccac
    11761 ttgtagcctg tacccttatt gggcttgtaa caggtcactt ggaagcaggg attatcctcg
    11821 gtggatcgct tcaaatgatt gcccttggtt ggtcaaatat cggtgctgct atcgctcctg
    11881 atgctgcact tgcttctgtc gctgctgcca ttatcatggt tcttggtggt gactttacca
    11941 agactggtat cggtgttgcc caagcggttg ctatccctct tgccgtagct ggacttttct
    12001 tgacaatgat tgttcgtaca atttcagttg gtttggttca tactgcagat gctgccgcta
    12061 aaaaaggtga cttcggcgct gtggagcgtg cgcatttcat tgcgctactc ttccaaggac
    12121 ttcgtatcgc gcttcctgca gctcttctcc ttatggtacc aactgaaact gtacaaagta
    12181 tccttagtgc catgccagac tggctcaaag atggtatggc tatcggtggt ggtatggtcg
    12241 ttgccgttgg ttacgccatg gttatcaaca tgatggcaac tcgtgaagta tggccattct
    12301 tcgctcttgg tttcgttctc gctgctgtgt cagatattac tctaatcgga ttcggtgcta
    12361 tcggtgttgc tatcgctctt atctaccttc acctttctaa aactggtgga aatggtggcg
    12421 gaggagccgc aacttctaac gacccaatcg gcgatatcct agaagactac taagataaga
    12481 aaggactgaa aacatcatga ctgaaaaact tcaattaact aaatcagatc gtaaaaaagt
    12541 ttggtggcgt tcaaccttct tacaagggtc ttggaacttt gaacggatgc aaaacttggg
    12601 ctgggcttat acactcattc cagctatcaa aaaactctat actaaaaaag aagatcaaat
    12661 cgctgctctt gagcgtcacc ttgagttctt caacactcat ccatacgtag ctgctccagt
    12721 catgggggtt actcttgcgc ttgaagaaga acgtgctaac ggtgtggaaa tcgatgacgc
    12781 tgctatccaa ggggtcaaaa tcggtatgat gggacctctt gctggtatcg gtgacccagt
    12841 attctggttt acagtacgcc caatccttgg atctctcggt gcttcacttg cccttactgg
    12901 caatatcttg ggtccactcc tcttctttgt tgcatggaac ttgattcgta tgtcattctt
    12961 gtggtatgtt caagagattg gatacaaggc tggatcagaa atcactaaag atatgtctgg
    13021 tggtatcctt caagatatca ctaaaggagc ttctatcctt gggatgttca ttcttgctgt
    13081 ccttgttcaa cgctgggtaa atattaaatt tgctttcgat gtttctaaag ttcaactaga
    13141 tgaaaaggct tatatccatt gggataaatt gccagaaggg tctaaaggta tccaagaagc
    13201 attcgcacaa gtaggacaag gattgtctca aactcctgaa aaagttacta ctttccaaca
    13261 aaacttggat atgttgattc ctggattatc aggactactc cttactttac tttgcatgta
    13321 cttacttaag aaaaaagtat ctccaatcac tattatcctt gccctcttcg cagtgggtat
    13381 tgtggcacat gttcttcaca tcatgtaatc aagcaactaa aaaggaacca ggttctaaaa
    13441 tctgattcct tttttctatg cttttattca gccaaggctc ccattggatc ccatggtgca
    13501 agtacaattg gttctgctcc ataggcagct tgttcttctg ctgtcagcaa ttccttacga
    13561 acaacgattt ggtatgtgta ttcgtccatc caagcgtctg aggcaacaaa gtaaccatct
    13621 gtaccgacct tgtctcccca tgagttttca accttccact tggttgattt accattttcg
    13681 tccaagtcaa cacctgtcaa gaccatggcg tgggtcatca agctttcgct atagtccaaa
    13741 cgtccagcct tgtcttgagt aagtttaatg tccatgcttg attcaaagtc ataaacatct
    13801 gtcgcaagga tgccagcctt acggttactg agctggccga catcagaacc aaaccaaaca
    13861 gtctcacctg cttgcatttg ggcaatcgcc aattctttca agcgctccat tggaacgttg
    13921 atgtaacgaa ctgcacggct accaaccaca ttccccaaca tctcaactgt gtaagatttt
    13981 ccgtaaggtt tatcagcagt tggagcattg ataacagaaa cgtagtcttc taaaggaaga
    14041 ttgacatatt tcttgtaaaa ctcttgtggt gtgattcctt tttcactttt gtagttgtta
    14101 tctttatcgc gataagcaaa gtcaaacttg cgtggtggaa gtcctaatga catagcaaga
    14161 aagttaaaga tttcttgcaa gaggtcttct ttcttagctt gaacagtcgc ttgatctgca
    14221 ccagaaacaa gcaagtcacg caagatttga gcatcttgac gaagcaattt attaaggatc
    14281 gcatttagct cacgactgct gctagatgaa acagactcag gataaactga cttaggcacg
    14341 acaccgtatt tttcaaagag ggaaacgacc atatcccatt gaccaccatc ttgttgaggt
    14401 gtttggagta agaagctaac cttgcggcta gtcaattctt ggtctgaagt cgcaatgact
    14461 tgctccaaga accagtttga tttctcatac ttatcccaga agaaagtgtg ggcttgtgac
    14521 aactcaaagt tctccaattt gtattgcgag atgagtttgt ggcggaaggt gttgagagcc
    14581 gcaaacatcc agcaacgacc agacgctttc tggttagtga ccttgtcctt ggttaaatcc
    14641 aatgagaaaa caggtgtgtt gtctacatgg ctttggcgac gttccagagc tgcaaaaatt
    14701 ccgttgtggc tagcagcatt ttcaatcgct tggtatttta catttgcttc atagttggca
    14761 aatagtttat cagtaaatga ttcttgaatc gcgttcatag attcctcctt ttattctaca
    14821 gtctattata actcttttca caaaggaagc aactaaaaaa cataaaaggt aaggacattc
    14881 tccctcacct ttttcgaata tatactcttc gaaaatctct tcaaaccacg tcaacgtcgc
    14941 cttgccgtac tcaagtacag cctgcggcta gtttcctagt ttgctctttg at
//
LOCUS       DBERAE010000049        14892 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.49, whole genome shotgun sequence.
ACCESSION   DBERAE010000049 DBERAE010000000
VERSION     DBERAE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.49"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(64..297)
                     /locus_tag="ACL70N_001838"
     CDS             complement(64..297)
                     /locus_tag="ACL70N_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS0590591.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(303..1295)
                     /gene="plsX"
                     /locus_tag="ACL70N_001839"
     CDS             complement(303..1295)
                     /gene="plsX"
                     /locus_tag="ACL70N_001839"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGS0590592.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1292..2062)
                     /gene="recO"
                     /locus_tag="ACL70N_001840"
     CDS             complement(1292..2062)
                     /gene="recO"
                     /locus_tag="ACL70N_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGS0590593.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2059..3228)
                     /locus_tag="ACL70N_001841"
     CDS             complement(2059..3228)
                     /locus_tag="ACL70N_001841"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0590594.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLKDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3377..4387
                     /locus_tag="ACL70N_001842"
     CDS             3377..4387
                     /locus_tag="ACL70N_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGS0590595.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVINAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(4406..4531)
                     /locus_tag="ACL70N_001843"
     CDS             complement(4406..4531)
                     /locus_tag="ACL70N_001843"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590596.1"
                     /translation="MKIKEQTRKLAAGCSKHRFEVADRTDEVSNIYLRQGDVDVV"
     gene            complement(4572..5009)
                     /locus_tag="ACL70N_001844"
     CDS             complement(4572..5009)
                     /locus_tag="ACL70N_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGS0590597.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5094..7727)
                     /gene="polA"
                     /locus_tag="ACL70N_001845"
     CDS             complement(5094..7727)
                     /gene="polA"
                     /locus_tag="ACL70N_001845"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGS0590598.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            7980..8890
                     /locus_tag="ACL70N_001846"
                     /pseudo
     CDS             7980..8890
                     /locus_tag="ACL70N_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603333.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            9018..9160
                     /locus_tag="ACL70N_001847"
                     /pseudo
     CDS             9018..9160
                     /locus_tag="ACL70N_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9297..10265)
                     /locus_tag="ACL70N_001848"
     CDS             complement(9297..10265)
                     /locus_tag="ACL70N_001848"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS0590599.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10410..11224)
                     /locus_tag="ACL70N_001849"
                     /pseudo
     CDS             complement(10410..11224)
                     /locus_tag="ACL70N_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(11249..11746)
                     /locus_tag="ACL70N_001850"
     CDS             complement(11249..11746)
                     /locus_tag="ACL70N_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGS0590600.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(11819..13180)
                     /gene="radA"
                     /locus_tag="ACL70N_001851"
     CDS             complement(11819..13180)
                     /gene="radA"
                     /locus_tag="ACL70N_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGS0590601.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(13194..13709)
                     /locus_tag="ACL70N_001852"
     CDS             complement(13194..13709)
                     /locus_tag="ACL70N_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0590602.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(13711..14154)
                     /locus_tag="ACL70N_001853"
     CDS             complement(13711..14154)
                     /locus_tag="ACL70N_001853"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGS0590603.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(14211..14308)
                     /gene="ffs"
                     /locus_tag="ACL70N_001854"
     ncRNA           complement(14211..14308)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL70N_001854"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(14341..14808)
                     /gene="tadA"
                     /locus_tag="ACL70N_001855"
     CDS             complement(14341..14808)
                     /gene="tadA"
                     /locus_tag="ACL70N_001855"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGS0590604.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
BASE COUNT         4372 a         3702 c         2678 g         4140 t
ORIGIN      
        1 agcttgtcca atatttctca tttctaaaaa ccatctactt ccgttgactt ggaactccga
       61 ttgctatttt ccttgaatga ttttaaccac atctcctaca ctttggagtt ggtcaatttc
      121 ctcatcgctg atttcgatac taaattcatc ttccagagtc aagataaact ccatcaagtc
      181 aacagaatcc gcatccaaat cgtctttcag actcaaggat tctgtcacga caaagtcctc
      241 tccctgtcgc tcttggataa tggtcacaat acggtcaaaa atttcttttt ctgtcatctc
      301 ttttattctc ctgaaaattc acgcgcagtc tgggcaacca cgtctgtttc tagcatggta
      361 cgaatctgac gaatcgtact ataaacagcc ttggcatcgc ttgagccatg agtcttgaca
      421 acaggtgcct taacaccaaa caagaccgct ccaccaacat ctgaataatt gagctgtttt
      481 ttcaaaccac tgaggctgtc cttgagaagg agggcaccta gtttcgctcg aagaccacca
      541 cctgtaatag ctgtcttgag caagcccacg attcccatag ctgtcccttc gatggatttg
      601 agcacagcgt ttcccgtgaa accatctgcc acaacaacat ctgcaacgcc attcatcaaa
      661 tcacgcgctt ccacgtttcc gataaagttc aaactttcat cagccgccag taattcataa
      721 gtttccttac gaagcgggtc acccttgcta ctctctgttc cgttgttgag caaaccaacg
      781 cgtggttgcg caatgccacg gacattttta gcatagaagg aacctagaac cgcatattga
      841 tggaggtgct gggctgtatt ttctgcattg gcaccaaggt ctagcatgtc aaaacctttt
      901 ccatcaacgg taggcaaggt agacatgagt ccaggacggt cgatattctt gatacgaccc
      961 acgatgaaga atcctgctgc caacaaggca cctgtattcc cagccgaaag gacagcgtct
     1021 gcttcaccat ctttgacagc cttggctgcc aataccatac tggcattttt cttattccta
     1081 atagctctcg taggttcatc atccgaatca atcttctcat ccgtatggat aatgctgacg
     1141 cgctctgtcg ctgtcagata ttgcttgatt ttagcttcat ctccgtaaag ttgaacctcg
     1201 atatctgaaa agtcagatag ggcttgattg acaccctcaa caatggcctg aggtgcgtaa
     1261 tcgcccccca tggcatctac tgcgattttt ttcatttctt ttcctctttt agtaattgtc
     1321 cccagtctgc tagggaatca ataaatttct ttgattttag gtgaatccca acgtactctt
     1381 catataattg atccataaat tggcgtagct cttgcttgat tccaggcttg agcgaaatgg
     1441 tctccaaagt ctcaaaatca atagcttgaa attgattgag cagatagggg atattgggat
     1501 tgagatgaca acgtctctta tcctcatgat aatgctctgg acagaggcag gctccatatt
     1561 tgaaagaaaa gtcaaaagcc tgaccaaccc gatggcagaa gacacactca ttaaaattga
     1621 ggctgattcc aaatcgagtc aaaatttgaa tttcaaaaat attggtcaaa acctgataat
     1681 ccaagcctgc ttccatcaac tccaaagtct tttgcaaaaa agcaaacaag ggagcatcct
     1741 gctgattgtc ctgcaaacta gcatctgcaa gagctgccac ataggtcgca taggccatga
     1801 caaagaggtc actattaatc ttgggaaaag tcatgacctc atgatagtct tcgatgtaac
     1861 tgagtccgtc atcattgatt cgcaagagaa atcgtgccaa caccaagggc tgaataacag
     1921 gcgccagctt agactgacca gcgtgtttga caaaaaacat gcgtttgcca acctgctctg
     1981 taaaaatttt gacgagcttg tcatcctcac gaaaattgcg attgtaaagc accaagcctt
     2041 gactcgtgat agactgaatc atgcttctct catgtactcc tcaagtcgtt tcatggcttc
     2101 tttgatagtc tccatgctgg ctgcataaga taggcggacg tagccttccc cgtaacgtcc
     2161 aaaggctgca ccagggataa aggcaacggc cttcttctga gcaaaatcct tcagaaaagc
     2221 aaaggagtct tgattgtagc ccgctggaat tttagcaaaa atatagaagg caccgtctgg
     2281 tttgataatc tcaaaaccaa gagcagtcat tttttcgatg atatagtccc gacgctggat
     2341 atattccttc ttcatgggct ccgcatcatt tttaccagcc gtcaaggctt ctaccgcagc
     2401 atgttgcgcc atggtatttg cggcagtgac caagtattgg tgactcttga ttaactgggc
     2461 tgtgaaggcc gcaggagcga aaatcagccc caaacgccaa cctgtcatgg catgcgattt
     2521 agacaaacca ttgataataa tagcctggtc tttcaacatc gttcctagag acacatgggc
     2581 ttcgcctgtg taggtcaatt ctgagtaaac ctcatcacag acaacaaaaa tttcgtactt
     2641 gcgtaaaaca gctgccaagg cctctaactg ctctcgactg taggtaattc ctgtcggatt
     2701 ggctggatag ttgagaataa ccgctttgag cttatcaccc tgctccaaaa tggccttctc
     2761 caacatctca ggagtcaaga caaaaccatt ttcagtcgta tcaatctcaa caatttctgc
     2821 cccaactaag ttaacaatcg gttcatagcc tggataagca ggagctggca aaagtacctt
     2881 gtctccctct tccaaaatag ccgtcaaagt cgcagataaa gcctctgtcg ccccaattgt
     2941 aaccaagatt tcattttcag gagcatagtc cagttggtac ttttccttaa caaagtcact
     3001 agctgcctga cgtagagtca gcagaccact catccctgta tagtaggatt ggttctgatc
     3061 aatcgctcgc ttggccgcct ccttgacatg gtctggcgtt gtaaaatcag gttcccccaa
     3121 ggtcaaacgc aagaccccag gaatctccga aatagcctgg tcaaactgac gaatcaacga
     3181 aacttgaatc ttatctaact gtttattaaa gcgcttagtt aagtccatag atacctccta
     3241 ctttcaaaac gtatctctat tatactacaa aagcctcccg accgcaaaaa tacattagag
     3301 aatagctttc cactttctat tttacttttc ctgtttatag gtctataatg gtaatagatt
     3361 ttatttggag gtttttatgt catttctatc aaaaaatgga gcaggtatct tggcctgcct
     3421 tctcatttct atcgtatctt ggtacttagg aggattcttc cctgtgattg gcgcgcccgt
     3481 ttttgccatt ttcataggca tgctcctaca tccctttctc tcgtcctata aacaactgga
     3541 tgctggtttg acctttagtt ccaagaagtt gctccaatat gccgttgtct tgcttggttt
     3601 tggtctcaat atctcgcagg tcttcgcagt tggccaatct tcactccctg tcatcctgtc
     3661 cactatctca atagctctga ttattgccta cctcttccag cgtttctttg cactggatac
     3721 aaaactggct accttggttg gagtaggttc ttctatctgt gggggttctg ccattgcagc
     3781 gacagcgccc gttattaatg ctaaggaaaa ggaagtagcc caagccattt ccgttatctt
     3841 tttcttcaat gtcttggctg cgctcatctt tccaaccctc ggcacctggc ttcatctatc
     3901 caatgaaggc ttcgccctct ttgcagggac tgcggtcaac gacacttcct ctgtaacggc
     3961 tgccgccagc gcttgggaca gtctttacca aagcaatacc ctcgagtctg caaccattgt
     4021 taaactcaca cgtactttgg ccattatccc tatcacgctc tttctatcct actggcaaag
     4081 tcgccaacaa gaaaacaagc aaagcctaca actgaaaaaa gtcttcccac tttttatcct
     4141 ttactttatc cttgcctctc tcctcactac actactcacc tctctaggtg tgtccagtag
     4201 tttctttacc cctctcaaag aactctctaa attccttatt gtcatggcca tgagtgctat
     4261 cggtctcaaa accaatctgg tcgctatggt caaatccagt ggaaaatcca ttcttcttgg
     4321 agccatctgc tggattgcca tcatcctcac cactcttggt atgcagaccc ttatcggcat
     4381 tttctaacac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtaggtata
     4441 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaacg gtgttttgag caacccgcag
     4501 ctagtttcct agtttgctct ttgattttca ttgagtataa cacaaaaggt agcccatcag
     4561 ctaccttttt cttatgcttc ctcaatcaag cgagtatgtt ctctcttgat acagcgattc
     4621 atcacgatat catcacatcc accatcacgc aaaatctctt ttgcttctaa actttcaagt
     4681 cctagctgtg cccaaaaaat cttggcatca gctttgagaa aatcacgcgc cacatcgggc
     4741 agaaattcac tgcgacgata aacattgaca atatctacag gaaaaggaat ttcagcgagg
     4801 ctagcataag ccttttcacc caagatttcg ccacctgccg ccttgggatt gactgggatg
     4861 attttatagc cccgagcctg catttccttt gttactcgat tgctggttgt ttcttcacgg
     4921 tcagacaaac ccaccacagc aagggtttta ctcgttgcga gatactgacg aatcacgcca
     4981 tcacttggat tgataaattc ttgactcata gaaatcctcc tttttcatca gtatagcaca
     5041 ttttgaaaag gtttgcagaa ttctactaca aaaaaggagg actagccccc tttttattta
     5101 gcctcgtacc aggttgcccc ttcattctca tctgcgataa gaggaacact gagttgaatg
     5161 gcttcttcca tggtttgttt caccaatttt tttatctcta ccaattcaga tttaggcact
     5221 tcaaggacga tttcatcgtg cacttgtaac agcatcttag tctgataacc acctgcaacc
     5281 aaggctttat ccagctgaat catggcaatc ttgagaatat ctgctgccga accctggata
     5341 ggtgagttga tagcagttcg ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata
     5401 tctggcaact cacggcgacg cttaaagagg gtctctacat agcccttatc acgcgcctcc
     5461 cgcaccactt catccatgta gtttttaata cctggaaaac gttcaaagta ggtatcaatg
     5521 taggctttgg cttccttacg actaattccc aaattattag acaagccaaa gtctgaaatc
     5581 ccataaacca ctccaaagtt aactgccttg gcattgcgac ggtcatttgc agtcacatta
     5641 tcaggacgct caatgccaaa gacccgcatg gctgtcgaag tatggatatc tgccccctct
     5701 tggaaggcct taatcaagtg ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc
     5761 tgtgaatagt cagagctgag tagcacacta tcctcccact ctggcacaaa agccttccga
     5821 atcaagcgcc cttgttccaa tcgggcagga atattttgca agtttggatc cacactagac
     5881 aaacgcccgg tctgggtcaa atcctgcata tagcgagtat gaatctttcc atcagccaaa
     5941 atccagtcct gcaagccaat tacataagta gattgaatct tagcaatttg acggtaatcc
     6001 aggattttct taacaatcgg agcaatagga gcgagacgct ccaacacatc cactgctgtc
     6061 gaataacctg tcttggtttt cttagtgtat tctagaggaa gtcccaattt ctcaaagaga
     6121 agcacgccca actgcttagg cgagttgaca ttaaactcct caccagccag ctcgtaaatc
     6181 tcttgagtca gtttttcaat gacaagctca ttttcagcct gcatctcaag caaggtctct
     6241 ttcttgacca caatcccagc aatttccatc ttggcaagga caaaagccag aggttgctcc
     6301 atatcataaa gaagctctaa ttgcccattt tcgctaagtt tttcaagtaa aataggctct
     6361 gtttctacca aaacagcaag tttacaagct aagtgttcca agaatttctc acgttcagga
     6421 atggcctttt taacaccctt accgtagaaa gtttcatcat caaccaagta agtctgacca
     6481 taaagactag cgatggtcgc aatttcattg tcctccacag tcgaaaggag gtatttagcc
     6541 aaacggatgt caaaagcagg cgcctgcaaa tctacaccaa aacgttgcaa aagaacttta
     6601 accttcttaa agtcataaac tctcagagat gttttttcta agaaatcctt gaaaatcggg
     6661 tcttgcaaca gctcaagctt gtctgtggca tagagctgat ccccacaaga ccaggcaaat
     6721 ccaaccaaat tatctgtatg gtaattctca ccaaaaagct caaagtggaa gatagactct
     6781 tcactcagca tatcttgact gatttggtca acaatagtaa aatccaaacc ctcagccaca
     6841 tcagctgacg acatatttaa agcctgcttg agctgtttga agcccatctc atcgtagaat
     6901 ttcccaagat tttcaacatc tggaccacta tagaccaagt cctctaaacc aatcgcaatc
     6961 ggtgccttgg tatcaatggt cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg
     7021 atgagatttt ccttcatctt agaagtcttc attccatcaa tattttcata aatcccctca
     7081 agcgaaccat gctccagcaa gagcttaata cccgtctttt caccgacttt ggtcacccca
     7141 gggatattat ccgacttatc acccatgagc gccttgagat cgataaactg agctggtgtg
     7201 aggcccattt cttccatgag gtaatctggc gtaaaggcct caaactcagc cacacctttc
     7261 ttggaaattt caaccaccgt atgctcatcc gtcagctgaa tcaaatcctt gtccccactg
     7321 acaatggtaa tatcaaaacc atcctgctct gctagcttat ccagcgtccc aatgatgtca
     7381 tccgcctcat actgagccag ctcatagtga cgaatcccca tatgatccag caactcacga
     7441 atgaaaggaa attgctcacg aaactcatca ggagtcttgg cccgaccacc cttatagtcc
     7501 gcatacatct ctgtccggaa ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc
     7561 ggctcaaccc gctccaacaa atgactcaac atcaactgaa aaccataaat cgcattggta
     7621 tgcaaaccag ccgcattctt aaaacggtcc aactgctgat acagcgcaaa aaacgcccga
     7681 aaagctacag aagacccatc aatcaataat aattttttct tatccataca cccattataa
     7741 aggaaagaat caaaaaatac cattgggaag agctagagca agtatttttc aaactttttc
     7801 cgaataaata gatagagcca gagaatttag taaacctaga tttaaaaatg tgctataata
     7861 tagtatattg aatctataat agtacacctt gactgctaaa atatttctat aaattaattt
     7921 gactttcctg atagagttgt tcacatctta tttcaattca ctatagaagg aggaaaagga
     7981 tgattctcag acatctggga attagcccga ccaatgactt ggttgctaag aaaattttca
     8041 gcaacccaga aatcacttgt caatttatcc gcgatatgct ggacttgcca gccaaaaatg
     8101 tgactatttt ggagggaagt aacattcatg tcttgccttc catgccctac tcagcgcagg
     8161 atttttatac cagtatagac gtcttggcgg agttggataa cggtactcaa gtaattattg
     8221 agattcaagt ccatcatcag aattttttca tcaatcactt gtgggcttac ctgtgcagtc
     8281 aggttaatca aaatcttgaa aaaattcgtc agcgagaagg tgatactcac tagatctaca
     8341 aacacatcgc tcctgtttac gtcattgcta tcgtggatag taattatttc tcagatgacc
     8401 tggcttttca tagctttagt atgcgcgaag acacaacagg tgaggtattg gcgattacca
     8461 acaatggaca ggaaaaccat ctggttaaga tggcattctt ggaattaaaa aatacagaga
     8521 aaccagcaaa gacaaggttc gcaagccatg gttggagttt ttcggcaaca agccctttac
     8581 ccagcaaccg caacgagcca ttagccaagc aaatcaactg ctggactaca agagctggtc
     8641 cgaggaggac aggaaaatgt ttagtcaact acatatgcga gaagaacaag tcttgttagc
     8701 acaggactat gccttggaaa ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg
     8761 gaaagttgaa ggaagggcag aaaggaaact ttttgccttc ctagacatag tacgccaagg
     8821 tcttctgact tctgaggttg ccagccagca attaggtatg tcagtatctg aatttgaggc
     8881 actgttgtaa aatggctcca taatatccat agtgggtaaa tcccctatgg atattatgga
     8941 gcctattttg tgtaaaaaaa aaagtcccat atgacctata atgaaaagcg acaaaacaac
     9001 tcattagaaa gaatcatatg gaacaattac attttatcac aaaattacta gacattaaag
     9061 accctaatgt ccagatttta aacatcatca ataaggatac acacaaggaa agcgtcgatt
     9121 caaatgctat cactgttcaa aaatgatggt cgctgaaact tatgatgacg tacagtcata
     9181 tttcttttct ttttattata tcacagtttt aaatctagct ttactagatt caccgctact
     9241 atctatttat tcggaaaaaa gacgaaaaaa cctgagaatc atctcaggct tggtcattaa
     9301 atttttttct caatatcgaa aagtggagaa agtggtcgtt tttcatgaat acgtacgata
     9361 gcatccccta ggagatgagc gattgaaatc tgctcaatct tatcaatcaa acgctcttct
     9421 ggcagataga tggtatccaa aacaaccaat ttcttaatag ctgatttttg gatattgtcc
     9481 gtagcaggac cagaaagaac tgggtgcgta cagcttgcat agacttcaac agcaccagct
     9541 tccgcaagag catctgccgc atgacaaatc gttccagcgg tatcaatcat atcatcaatc
     9601 aagatacaag tcttgccttc aaccttaccg atgatgttca taacttcact agtattcatc
     9661 ttatcaacgc tacgacgttt atcaataata gcgatagatg ttttcaaaaa ttctgccaac
     9721 ttacgagcac gagtcacccc tccatggtcc gggctgacaa ccacatagtc agaaccaacc
     9781 ataccacgac gctcaaaata atctgcaatc agaggagcac ccatcaaatg atccacagga
     9841 atatcaaaga atccttgaat ttgcgcagca tgcaagtcga tggtcaataa acgatccact
     9901 ccagctactt caagcatatt tgcgacaagt tttgaagtga ttggctcacg cgctctcgcc
     9961 tttctatcct gacgtgcata cccatagtaa ggcatgacaa cattgacaga ttctgcactc
    10021 gcacgcttca aagcatctac cataatcaaa atttcaagca gattgtcatt tacaggcgaa
    10081 ctagttgatt gtaagataaa gacgtgtttc ccacggattg attcttcaat gttgacctga
    10141 atctctccat ctgaaaattg gcgaacactt gatttcccca actctatccc aatctcctgc
    10201 gccacacgtt ctgccaattc tttattagaa gaaagggcaa acagctttaa atcagaaaaa
    10261 gacatgattt cctccggtat atatgtatag cttgtgcttt tcacaagatt ttccatctac
    10321 cattgtagcg ctttttgcac tatttttcaa tcaaaaataa aagaagggca ccatatttgt
    10381 acccttgcat cattcttttg aaaaatattc taggtcatca actcattgtg tttctcaaca
    10441 aagcaataag catgataaaa accatagaga gcaatagccg taaccactgg aatcgctaaa
    10501 ggcaactctg tttccaactc cacaaaagga gagttaaaca agaagtgagt tcccaaggct
    10561 aaacctagaa aaataaggcc ctgtttcttg ccaaccttct gtcctttata ggctctgtaa
    10621 agcaagtaaa cacctactac agctagacct gaaaaagtcc agtgagaggc aattcctgag
    10681 atgatacgct ctaaaattcg cgaaatagta aagtcaaagc cctctggcaa atccgtacga
    10741 atataaccaa tatcctcaat catttggaat cccaaaccgg aagcaattcc aagtaaaaac
    10801 aaagatttta attttcgcac aggaatcaaa gccaaaacaa aaacaagtga caataatttc
    10861 aagggttctt ctaccaaagg agccacaata gcactttcaa aggcatttaa aaatggacta
    10921 tctgggaaaa gaacccccag taaatcatgg atataagtat tagcaaaact agacaaccag
    10981 cctgaaagga acatccctcc caataaagac agaatcaaaa ccttctttgg caattcccat
    11041 ttttcccaat acggaagaga aaataaagag ccggaatcat gtaaaagaga gctagaaaga
    11101 tagaaactcc cattagtcca tattccgcac ctgacctcga accgtccgta tagtagatgg
    11161 tttcatactg taaaccaata catagcaata aaataaaaat aaataaaata ctgcttttct
    11221 tcatacactt tctttctaaa tgaagtattt ataattctac gactgtcata cttcctgtat
    11281 caacattgta aatggcacca gagataatga catcgtctgg tattagggga gactcgataa
    11341 gcagttgcat atcctcgcgt acactctctt ctatatcttg gaagggcaag aagtcctggt
    11401 ctgacacatc tacacctaat tcctctttta aatactcctg aaaaggttca ttttcaaagg
    11461 tctgagcacc acagtctgta tggtgcaata ccacaatctc tcttgtcccc atttgttgct
    11521 gggaaataac tagcgaacga atcatgtctt cagtcactcg accacctgca ttccgcaaga
    11581 tatgagcatc cccaagtgcc aagcccagag cttgcgcaac gtgcagacga gagtccatac
    11641 aggtcacaat agctactctt gttttgggtt taagtggcag atttaactgc ccatgtaggg
    11701 caacataagc ctgattggct tgcataaact gttcaaaata cgacacgatt ccctccttga
    11761 aaatttgata gtcaaatatt tctcctatct tatcattttt aagagaattt gtcacggatt
    11821 atgcaaagac ctttttcaag acttcctgaa tcgttgtcac gccaatgacc tgaatttcct
    11881 taggcagagt gattcctgtc aaggaattct taggtacata aatcttagta aagcccagtt
    11941 tagcagcttc gttgatgcgt tgctcaatac gattcacgcg ccgaatctct cctgtcaagc
    12001 ccagttctcc gacaaaacat tcctgaggat tagttggctt gtctttgtag ctcgaagcaa
    12061 tagcaactgc aacagccaag tcaatcgcag gttcatccaa tttaacacca ccagcagatt
    12121 tgagataggc atcctgattt tgcaagagaa gccctgcccg tttttccaaa acagccataa
    12181 tcaagctagc acggttaaaa tcaagtcctg tcgtagtacg cttggcattt ccaaacatgg
    12241 tcggtgttac caaagcctga acctccgcca aaatcggacg cgtcccttcc atggttacaa
    12301 cgatggagga accagtcgcc ccatccaaac gctcttctag gaaaacttga ctcggattga
    12361 gtacctcaac caagccgccc gactgcatct caaaaatccc aatctcatta gtggaaccaa
    12421 aacgattttt gaccgctctc aaaatacgaa aggtgtggtg acgctcccct tcaaagtaaa
    12481 gcaccgtatc caccatatgc tccaacatac gaggcccagc caaggttcct tctttggtca
    12541 catgacctac gataaagatg gcaatgttat tggtcttggc caactgcatg agttcagcgg
    12601 tcacttcacg cacctgagaa acagacccct gcacccctga aatctcagga gacatgatgg
    12661 tctggatgga atcaataatg agaaagtctg gctggatacg ctccacttct gcacgaacac
    12721 tctgcatatt ggtctctgca tagagataaa actcactatc aatatcacct aagcgctctg
    12781 cacgtagttt aatctgctgg gcagactcct ccccactgac atagagaact gtccccactt
    12841 gggacaactg ggttgagact tgtaggagaa gagttgattt cccaatccca ggatccccac
    12901 cgatgaggac gagacttcct ggtaccactc cgcctccaag cacacggttg aattcctcca
    12961 tctccgtctt ggttcgattg acattgatgg aagtcacctc agctagtttc atgggcttgg
    13021 ttttctcacc tgtcaaggac acacgcgcat tcttgacctc ggcaacctca acctcttcca
    13081 caaaagaaga ccaagaccca cagttggggc aacgtcccag atatttaggg gaattatacc
    13141 cacaattttg acatacaaat gtcgcttttt tctttgcgat gacaaacctc tttctatatc
    13201 tctaactcac actcaatcac ttggcaaaaa tcaatcttct catttggcac aaactggcgc
    13261 atgagcattc gatgagcaac aactaccaca gtctgatgtt ctcgatactt agacatacat
    13321 tctagaaacc gagacttcat ttccgtagct gtctcatatt gaataggact attaggaagc
    13381 aactccccct tgttttctaa aaacagtctt ctagctgttt caaaattttc tattcctgtt
    13441 ttatagacct gccattcatg taataaaggc tctactctta aaggaagacc cgtagcacag
    13501 accacatacg aagccgtttc taaagctctt gtgactgcag aagatacgat tatttcagct
    13561 gacgagagta aaggattttt gctcaatttc tggacttgct gccgtcccat ctcagacaag
    13621 ggtgccaaat ctatcccaaa tcctatataa gaacgctcct ctaactcacg gtaatctggc
    13681 tccccatgac gtacaaagat aatcttcatt ctagtgccct gtcgatccaa atccaccagt
    13741 tcgaacgcca tcagctgcat ctccatctgc aattaagaaa gtagcaaaaa cagcctggac
    13801 aatacgttcc ccaacttcaa gaacaacctc ttgatctgtg atattcttca tctgcgcaaa
    13861 aatatgccct tcatttccag gatttccata ataatcccca tcaatgaccc caactgagtt
    13921 aattaaaacc aagcccttct tacgaggatt tgaagaacga tcatagaggt agagaacctc
    13981 agtcggctgc atataagcct taacccctgt cggaaccaag acaatctctc ctggcgcaac
    14041 aactgtacgc acagcaacct ttaagtcgta accagccgca tgcgctgtct cacgcttggg
    14101 caataaattt tcatctgtaa aactcgaaac caattcaaaa ccacgaattt tcataatttt
    14161 ctcttttcta ttatcattta ttctagatta ttctatctta tttattcgga aaaagcacga
    14221 aaaaaagagc acacaattca aatcgcttag ggctgctgga ttcctcccct gacccgcttc
    14281 acgcagaact gttgctccac tatttattat atcacattcc tattcatttt aaaagcaaaa
    14341 ttattttttc cgtctatttc taaaaaaatc ctgcatgata gctgcgcatt catcttccaa
    14401 aattcctatt tcaacctcca cacgatgatt gagacgctca tctgtcaaga tattgtacaa
    14461 actcccagca gcgccaaatt tctggttttt agccccatag accacatttg gaatgcgggc
    14521 aagcccaatc gctccactac acatgacaca aggttcaatg gtcacaaaaa gtgtgcaatc
    14581 cagcaagcgc cagctctcct cactcaagtt cgcatcctct atagccataa tttccgcatg
    14641 cataaccgct cgctgtaatt cctcacgcgc attatgccca cgaccaatga tttccccatc
    14701 tttgacaatc acacaaccaa ttggaatttc atcgtgttca agagcaatct cagcctctct
    14761 caaagcctcc ctcataaaga cttctttttc ttcaagcgta taatacatct cttttctctt
    14821 ttcctactta tcgattttat tattatatca tgaatcccaa cacaaaaaaa gccaccgaat
    14881 gcggtgactc ta
//
LOCUS       DBERAE010000050        14320 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.50, whole genome shotgun sequence.
ACCESSION   DBERAE010000050 DBERAE010000000
VERSION     DBERAE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.50"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(83..646)
                     /locus_tag="ACL70N_001856"
     CDS             complement(83..646)
                     /locus_tag="ACL70N_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0590605.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="ACL70N_001857"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="ACL70N_001857"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGS0590606.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="ACL70N_001858"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="ACL70N_001858"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGS0590607.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="ACL70N_001859"
     CDS             2112..3782
                     /locus_tag="ACL70N_001859"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGS0590608.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="ACL70N_001860"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="ACL70N_001860"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGS0590609.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5340..6044
                     /gene="yycF"
                     /locus_tag="ACL70N_001861"
     CDS             5340..6044
                     /gene="yycF"
                     /locus_tag="ACL70N_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGS0590610.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6037..7386
                     /gene="vicK"
                     /locus_tag="ACL70N_001862"
     CDS             6037..7386
                     /gene="vicK"
                     /locus_tag="ACL70N_001862"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGS0590611.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7388..8197
                     /locus_tag="ACL70N_001863"
     CDS             7388..8197
                     /locus_tag="ACL70N_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS0590612.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8288..8530
                     /gene="relB"
                     /locus_tag="ACL70N_001864"
     CDS             8288..8530
                     /gene="relB"
                     /locus_tag="ACL70N_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS0590613.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8532..8786
                     /locus_tag="ACL70N_001865"
     CDS             8532..8786
                     /locus_tag="ACL70N_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS0590614.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8833..9576
                     /locus_tag="ACL70N_001866"
                     /pseudo
     CDS             8833..9576
                     /locus_tag="ACL70N_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(9877..10863)
                     /locus_tag="ACL70N_001867"
     CDS             complement(9877..10863)
                     /locus_tag="ACL70N_001867"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGS0590615.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11057..13525
                     /gene="gyrA"
                     /locus_tag="ACL70N_001868"
     CDS             11057..13525
                     /gene="gyrA"
                     /locus_tag="ACL70N_001868"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGS0590616.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            13525..14268
                     /gene="srtA"
                     /locus_tag="ACL70N_001869"
     CDS             13525..14268
                     /gene="srtA"
                     /locus_tag="ACL70N_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGS0590617.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4384 a         2482 c         3189 g         4265 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaaggg ctccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acgatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtagccccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gcagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgacc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcaa aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttactatag tttcaaacta taaaaccata
     1981 taaaatttaa gaaaggactc taaaagcctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgaca cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctggaaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggatggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gaccttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agccttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgacctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atctgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtacta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatctcttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga ttcctggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatccg gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actttggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt ggtataatag tagagaaaaa ggtgaacata
     5341 tgaaaaaaat actaattgta gatgatgaga aaccaatctc ggatattatc aagtttaata
     5401 tgaccaagga aggttacgaa gttgtaactg cttttaatgg tcgtgaagcg ctagagcaat
     5461 ttgaagcaga gcaaccagat attattattc tggatttgat gcttccagaa attgatggtt
     5521 tagaagttgc taagaccatt cgtaagacaa gcagtgtgcc cattcttatg ctttcagcca
     5581 aagatagtga atttgataag gttatcggtt tggaacttgg ggcagatgac tatgtaacga
     5641 aacccttctc caatcgtgag ttgcaggcgc gtgttaaagc tcttctgcgt cgttctcaac
     5701 ctatgccagt agatggtcag gaagcagata gtaaacctca acctatccaa attggggatt
     5761 tagaaattgt tccagacgcc tacgtggcta aaaaatatgg cgaagaacta gacttaaccc
     5821 atcgtgaatt tgagcttttg tatcatttag catcgcatac aggtcaagtc atcacgcgcg
     5881 aacacttgct tgagactgtc tggggttatg actattttgg tgatgtccgt acagttgatg
     5941 tgactgtacg acgtctgcgt gagaagattg aagatacgcc cagccgacca gagtatatct
     6001 tgacgcgccg tggagtaggg tattacatga gaaataatgc ttgatttact gaaacaaacc
     6061 atttttacca gagattttat ctttatcctg attttgttag gtttcatcct tgttgtgacc
     6121 ctcttattac tggaaaatag acgtgataat attcagttga agcaaatcaa tcaaaaggtt
     6181 aaagatttga ttgcaggaga ttattccaag gttcttgata tgcaaggtgg gtctgaaatc
     6241 accaatatta ccaataattt gaatgacttg tcggaggtta ttcgtctcac tcaggaaaat
     6301 ctagaacaag agagtaagag gctaaatagt attctgtttt atatgacaga tggggttctt
     6361 gcgaccaacc gtcggggtca gattatcatg attaacgata cagccaagaa gcaactgggg
     6421 ttggttaagg aagatgttct gaatagaagc attttggaat tgctcaagat agaagaaaac
     6481 tatgaattgc gtgatttgat tacccaaagt ccagaattgt tgctagattc ccaagatatc
     6541 aatggcgaat atttgaacct tcgagttcgc tttgccttga tacgtcgaga gtctggcttt
     6601 atttcaggtt tggtggctgt tttgcatgat acgacggagc aggagaagga agaacgcgaa
     6661 cgaagactct ttgtttccaa tgttagccat gagttacgga ctcctctgac tagcgtaaaa
     6721 tcctatcttg aagccttgga tgagggggct ttgtgtgaaa ctgtagcacc agactttatc
     6781 aaggtttctc ttgatgagac caaccgtatg atgcgcatgg tgacggatct cctccatctt
     6841 tcacgtattg ataatgctac cagtcaccta gatgtggaac tgattaactt cactgctttt
     6901 attaccttta tcctcaatcg ttttgacaag atgaaaggac aggaaaagga gaaaaaatat
     6961 gagttggtga gagattatcc catcaattct atctggatgg aaattgatac agataagatg
     7021 acgcaggttg tcgacaatat tttaaataat gctattaagt attcgccaga tgggggtaaa
     7081 atcactgtca gaatgaagac aactgaagac cagatgattt tatccatttc tgaccacggt
     7141 ttggggattc ctaagcagga tttaccacgt atctttgacc gtttctatcg tgtggatcgt
     7201 gctagaagtc gtgcgcaagg tggtacaggt ctaggactgt ctatcgctaa agaaattatc
     7261 aaacaacata agggctttat ttgggccaag agtgaatacg gcaagggttc aacctttacc
     7321 attgtgctcc cttatgataa ggatgcagtg aaagaagaag tatgggagga tgaagtagaa
     7381 gactagaatg agtgaaatag gctttaaata cagtatttta gcgtcgggtt ccagtggaaa
     7441 ttctttttat ctggaaacct caaaaaagaa gcttttagta gatgcaggct tgtctggcaa
     7501 gaaaattacc agtctgctag ctgaaattaa ccgtaagcca gaagacctgg atgccatctt
     7561 gattacccat gagcattcag atcatatcca tggagtaggc gttttggctc gcaagtatgg
     7621 tatggatctt tatgccaatg aaaagacctg gcaagctatg gaaaatagta aatatcttgg
     7681 caaggtggat tcttcgcaaa agcatatttt tgaaatgggt aaaaccaaaa cctttggaga
     7741 tatcgacatc gagagttttg gtgtaagcca tgatgcagtc gcaccgcagt tctatcgctt
     7801 tatgaaggat gataagagtt ttgtcctttt gacagataca ggttatgtca gtgaccgtat
     7861 ggcgggcatt gtcgaaaatg cggatggcta tcttatcgag gccaaccatg atgtagagat
     7921 tttgcgatca ggttcttacg cttggcgact caaacaacga atcctatctg accttggtca
     7981 cctttctaac gaggacggtg ctgaagctat gattcggacg ctaggaaatc gtactaagaa
     8041 gatttacctt gggcatttat ctaaggaaaa taatatcaag gaactggctc atatgaccat
     8101 ggtcaatcag ctggctcaag ctgatctggg agtcggagta gactttaagg tttatgatac
     8161 ctcaccagat accgcaacac cattgacaga gatatagaaa gaacgctgag aaggtgttct
     8221 ttttatattg actgaacacc taaaaagtaa tacaatggtg ttaccattaa aaaagggagc
     8281 acaaaagatg actactatta cattaaaagt ttctgaagct gataaaacat ttatgaaagc
     8341 aatggctaag tttgaaggag tttccctttc ggaacttatt cgcaccaaaa ctcttgaagc
     8401 cctagaagat gaatacgatg ctcgtgtggc agatttagcc tatcaagagt atttagaaga
     8461 cttggaaaaa ggagttgaac ccattacttg ggaagaaatg atgcatgatt taggcttgaa
     8521 ggatgaataa tttgtataaa ttagttccaa caagacgttt tatcaagcaa ttgaaaaaat
     8581 tggaccgtta tacgcagaag ctaattacaa actatttaca aaccaatgtt ttggaaggtc
     8641 caagacgaca cggaaaggct ttggttggta atcgcgttgg tcaatggcgc tatagaattg
     8701 gtaattatcg agttatcgta caaattgtag atgatgaatt agtcgttgct actctagaag
     8761 ttggtcatcg gagagatatt tattgaatta aagctgagta ataacaatat agaaagtaag
     8821 gagagtaaaa atttgaagaa aaaatggtta tttgcagatt attatgatac aacaattatt
     8881 ttacttgctt taatctctgt tattctggta ttacttggat ttgctgagat gactgatttg
     8941 gacaatccgc cttatagtat tattgattta gtaatctggg gtgtttttgt aattgattat
     9001 agttggcgct tttttattac taaaagaaaa tggcgcttta ttcttgaaaa tatttttgat
     9061 ttattgacca ttctcccttt aaatgctatt tttacagtgt ttcgattagg acgtatcttc
     9121 cgcttagcaa ggctgacaaa attactgaaa ctgactcgtt tacttagaat aattggactt
     9181 acaggtaaac tagaaagaaa aattagtaga ttcttacgaa caaatggatt gatttatatc
     9241 ttgtatgtta atatctttat tgttctagta gggagttcga ttttatccgt tgttgaagaa
     9301 aaatccttct cagatagtct ttggtgggct cttgtgacag taactactgt tggttatggt
     9361 gatattgttc cagtttccct ttttgggaaa tggctagcag ttttactgat gcttgtcggt
     9421 attggaacaa tagggatgct aacaagtgct ttgacgaact tttttgtaaa ggataatcca
     9481 gatgaacaga taaaacttga taaactcaaa gacgaattat cgagctaaag aatattaata
     9541 gagaaacaat ctgaaaaaat cgaagaacta cattgaatga taaaagactt agttgaaaaa
     9601 atatcataaa ggtgagacaa aataaaactt gattcgagga gaaatcaagt aagttttgac
     9661 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta tagagaaata
     9721 aaataaaatc tgaacaaatc aattaggaat ttaaagcatt ttataacaac gttttagagt
     9781 aatggggtgc tatttcaact tcaacctact ataatacaga aaaaaataca gaaaaaaaca
     9841 actccctgat gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa
     9901 ttctggattt ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat
     9961 tttttgagtt tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc
    10021 aacaacagct ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac
    10081 tgaaagtgga agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc
    10141 tactgcgata ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg
    10201 aacaccttcg aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa
    10261 ttcttcaaga tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc
    10321 gtgttcaccc atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag
    10381 tgcttgacgg aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg
    10441 gaaaccagag aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag
    10501 gaagatacct ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag
    10561 gtttttacct acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat
    10621 cacaacaagg tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga
    10681 agtgaaggca agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg
    10741 tggaatttcg ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta
    10801 agatgaacct acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt
    10861 cattgtttta aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta
    10921 tcacttttaa aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt
    10981 ggtttagagg ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga
    11041 aatgaggcat ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat
    11101 gaaggcaagt tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt
    11161 tcgagatggc ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt
    11221 gaccccagac aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata
    11281 tcacccacac ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag
    11341 ctaccgttac atgcttgtag atggtcatgg gaattttggt tccatggatg gagatagtgc
    11401 tgccgctcaa cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga
    11461 tatcaacaaa aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt
    11521 ggtcttgcca gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg
    11581 gatggcaacc aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt
    11641 catggataat cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt
    11701 tccaactggt gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa
    11761 aggttcgatt gtcctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg
    11821 tatcgttgta acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt
    11881 tcgcttggtt caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg
    11941 tgaaggtgtt cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa
    12001 taacctcttc aaaatgaccc aaatgcaaac caattttgga ttcaatatgc tcgctatcca
    12061 aaatggtata ccgaaaattt tgtctcttcg tcagattttg gatgcttata ttgagcacca
    12121 aaaagaagtg gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca
    12181 tatcttagaa ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg
    12241 tgctagtgaa acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga
    12301 acgtcaaagt caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga
    12361 taagattcaa tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct
    12421 tgctaagcct gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa
    12481 attttctgat aaacgccgta cagagttgat ggttggacag atcttgagtc tcgaggatga
    12541 ggacttgatt gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg
    12601 tttggatcag gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg
    12661 agtgaaagat gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct
    12721 cttcttcaca aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg
    12781 tcggactgcc aaagggctac cagtagtcaa tctcttgaaa ttggatgaag atgaaagtat
    12841 tcagacggtt atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac
    12901 ccgtcacggt attgtgaaga gaactagtgt taaggagttt gccaatattc gtcaaaatgg
    12961 tctcaaagcg ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tgacagaagg
    13021 agatatggat attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc
    13081 cgttcgtggt atgagccgta tcgccactgg tgtgaaaggt gttaaccttc gtgaaggaga
    13141 cacagttgtt ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa
    13201 aggatatggt aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg
    13261 aatgcagaca gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca
    13321 aggggatgag gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc
    13381 caatatttca caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga
    13441 tgctcagata gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga
    13501 aaacgaaaca gaaggtgaag cataatgtct caaaaaaata ataaaaagaa aaacaagcga
    13561 aaaaatctgc tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt
    13621 tttaatactc aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc
    13681 caggtatcaa aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat
    13741 tctgtcaaag ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta
    13801 ccagttattg ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga
    13861 cttgataatg ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga
    13921 gaaggaaatt atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg
    13981 ttattttctc ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat
    14041 aaagtttata cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa
    14101 gttgatgata gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct
    14161 acagaacgta ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct
    14221 gatgaaattc taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg
    14281 aaatcatgga tttcactgat tttttaagat tttcataaaa
//
LOCUS       DBERAE010000051        13884 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.51, whole genome shotgun sequence.
ACCESSION   DBERAE010000051 DBERAE010000000
VERSION     DBERAE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.51"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(93..1142)
                     /locus_tag="ACL70N_001870"
     CDS             complement(93..1142)
                     /locus_tag="ACL70N_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590618.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(1139..1870)
                     /locus_tag="ACL70N_001871"
     CDS             complement(1139..1870)
                     /locus_tag="ACL70N_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590619.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1938..2348
                     /locus_tag="ACL70N_001872"
     CDS             1938..2348
                     /locus_tag="ACL70N_001872"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS0590620.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            2358..2645
                     /locus_tag="ACL70N_001873"
     CDS             2358..2645
                     /locus_tag="ACL70N_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590621.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(3011..4147)
                     /gene="dnaJ"
                     /locus_tag="ACL70N_001874"
     CDS             complement(3011..4147)
                     /gene="dnaJ"
                     /locus_tag="ACL70N_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGS0590622.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(4352..4705)
                     /locus_tag="ACL70N_001875"
     CDS             complement(4352..4705)
                     /locus_tag="ACL70N_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590623.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(4718..6541)
                     /gene="dnaK"
                     /locus_tag="ACL70N_001876"
     CDS             complement(4718..6541)
                     /gene="dnaK"
                     /locus_tag="ACL70N_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGS0590624.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(7021..7545)
                     /gene="grpE"
                     /locus_tag="ACL70N_001877"
     CDS             complement(7021..7545)
                     /gene="grpE"
                     /locus_tag="ACL70N_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGS0590625.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(7572..8606)
                     /gene="hrcA"
                     /locus_tag="ACL70N_001878"
     CDS             complement(7572..8606)
                     /gene="hrcA"
                     /locus_tag="ACL70N_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGS0590626.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(8770..9279)
                     /locus_tag="ACL70N_001879"
     CDS             complement(8770..9279)
                     /locus_tag="ACL70N_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGS0590627.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            9886..12219
                     /gene="hsdR"
                     /locus_tag="ACL70N_001880"
     CDS             9886..12219
                     /gene="hsdR"
                     /locus_tag="ACL70N_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGS0590628.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            12232..13695
                     /locus_tag="ACL70N_001881"
     CDS             12232..13695
                     /locus_tag="ACL70N_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS0590629.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            13695..>13884
                     /locus_tag="ACL70N_001882"
     CDS             13695..>13884
                     /locus_tag="ACL70N_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGS0590630.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         4306 a         2802 c         2711 g         4065 t
ORIGIN      
        1 agtctctacg gaccaaccat tatcctgtag taacaaaaaa gaagctgaga cagactgaac
       61 tcaacttctt ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg ttttacctga
      121 taaggcaaat acaagactag taaaaccaaa ccagctccta gtaaggctag aagggccagt
      181 ttttcttgga aggtaatcaa cccaacaact aattccacaa gtaaaacaaa actggtcaat
      241 cctcgaacta cctcctgtaa gcctttttcc ttttgcccct tgtccagcgg aaagagttgg
      301 gtcaaatact ggtagtcaaa ggcatgatag agggccagca actggaagag caagaggtag
      361 ttaaagagaa ctaccactgc tgtcgcaatc caagcttgct cgataaaaac ctgcgccagt
      421 acggaaagta atagaagacg aagactgaga gcaaagaggt cgccatttcg cagataagaa
      481 cgcagataga gattttgcca aatcttccca ggcaccttct gaacagcctt taagataaag
      541 tccagatagg cacgacgctt aacgctgttt gaaattccct tgacctgcgt aaagagggca
      601 aagaaacgaa gcaagacttg cttacgcttg ctttcttgag aaataacata gtcccagtcc
      661 agtccagttt cagtgaaaaa tttgctggcc ttttgacgaa agtggaaata ttttcctacc
      721 cccaataaaa gcacatagag cagaaaaact ggcaagccat aacccattgc taaaaataaa
      781 ggcgcaaata acagcaagaa aagggtctgt acaaagagcc aaaagactag ggaaatgcca
      841 gtttgacgct tgagatggag cttgatttcc tcttctccaa ctaagagaaa gagcttgtct
      901 ggagcctcca tataggtggc aattcctccc caaagtaaaa gtaaaacaga cgtaattcct
      961 acaaacaaaa ggataggcca atgattttca ggaaaatgtt gtaagagttg actgtactgg
     1021 taggctagaa agcccaacag gacaagcagg aacaagacaa agtggtcatt gagcacatag
     1081 cgcagataac caagacactc cttacgaaag gcctgctttc tctttaaaaa caagtctttc
     1141 ataggtcctc ctcttttgtc agagccaagt aaatatcatt caaactagcc tcaggcatat
     1201 caaaggcttc gcgtagttgc aggagattgc ctttggcacg cacctctccc ttgtgaagaa
     1261 tgacaaaggc atcacacatc ttctccgccg aatccagcac gtgggtactc atgagaatag
     1321 acttgccctt ttgcttctcc acttccaaaa gctgaatcaa atcagaaata gccagcggat
     1381 caagaccaag gaaaggctca tccacgatga aaagacttgg atccaccaca aaagcacaga
     1441 taatcatgac cttctgcttc atcccttttg aaaaatgaac agggaaccag tctaatttct
     1501 gttccaaacg gaacattttt aacaagggct ctactcgttc gaaagccact ttttgctcaa
     1561 taccgtaagc catagcaacc gtttcgatat gctctctgag ggtcaattcc tcatacagac
     1621 taggcgtctc aggaatgtag ccaatctgct tgcggtagct agtcgcatct ccttgcagag
     1681 tcaggccatt gatattgatg gagccactat aaggtgccaa cagaccgata atctcattga
     1741 tcgtcgttga tttcccagca ccattgagac caatcaaacc gaccaactgc ccactttcaa
     1801 cagtaaagga cacatctttc aaaacaggaa catgaacata gccacctgtc aggtttttaa
     1861 tttctaacat attttctcca aatctggtat aatgtagcta tattatatca aaattcagta
     1921 cagtagaggt agattttatg tcagattgca ttttttgtaa aatcatcgca ggggaaattc
     1981 ctgcttcaaa agtatatgaa gatgagcagg tccttgcctt tcttgatatc tctcaagtaa
     2041 cactaggaca caccttggtc gtgccaaaag aacactatcg caatcttttg gagatgaatg
     2101 ctacgagcgc cagccaactc tttgcccaag taccaaaagt agctcaaaaa gtcatgaaag
     2161 tcactaaggc tgctggtatg aatatcattt ccaactgtga agaagtcgct ggtcaaacag
     2221 tttttcatac tcacgttcac cttgtgcctc gctacagtgc tgacgatgac ctcaagattg
     2281 attttatcgc ccacgaacca gactttgaca aacttgctca agtcgctgaa accatcaaaa
     2341 acgcttaagg agttgctatg aaattatcca acctactgct atttgcagga gctgcagccg
     2401 gaagttatct ggttacaaaa aatcgccaaa ccatcacaga tgaagtctta aataccactg
     2461 accgcgttca agctatcaaa gacgatgtgg atattatcca aaatagcctg caaatcatcg
     2521 accagcaaaa agaacttatc aaggaatacc aagaagactt gacttacaag tttaaggtct
     2581 tggaaaagga tatccagact agactagctg tgataaaaga aatgcaggga actgaagata
     2641 agtaaaaaga gcccccggct cttttttaaa acgtaaacaa gttatagtga attgaattta
     2701 gaatagcaca tcatagtttc taaagcattg ttagagatta ctttaaaatc ctcttatcaa
     2761 tttgttcata ttctatttca atctactata tatatcccat caactatgca tcataattta
     2821 ggtaactcat actcaataaa aatcaaaaag caaactagaa agctaggcac agactgctca
     2881 aaacaccgtt ttaaggttgt ggatagaact gacgaagtca gctcaaaaca ctgttttgag
     2941 gttgtagata cgactcacat atatacggca agccgacgct gacgtggttt gaagagattt
     3001 tcgaagagta ttattctcca tcaaaggcat ctttaatatg gtcaaagaag ccttttttct
     3061 ttggatttac tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt
     3121 cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc
     3181 cacgaaggct cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct
     3241 ctggaataac caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag
     3301 ccgcttggac aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact
     3361 tgtcgctagc ttctacagaa actactacat acaagtcacc ataaggtcca ccgttaaagc
     3421 ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt
     3481 tcacatgtac gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat
     3541 atttgatttc ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac
     3601 caagaggagt ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga
     3661 ctggacttgt ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat
     3721 gatacttaac ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat
     3781 actggagatc atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga
     3841 agaaacttga gaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccgccga
     3901 aaccaccagc tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag
     3961 cacgtttttg gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct
     4021 cagcaccagg ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct
     4081 ttttgatctc gtctgccgaa gcgttttttg acacccccag acgatcataa aattcagtat
     4141 tgttcataca agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg
     4201 agcgacgctc ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt
     4261 tcttttatat tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa
     4321 cagaggctgg gttgcaacct ctgtggttag attattcatt tgaaataaaa atggttgtat
     4381 tatctctagt agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt
     4441 gtgggtcttg tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca
     4501 taacatcttt aaacacagaa gtgtagtcat atttactctt accaacagct acttctgtaa
     4561 attctttata aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat
     4621 aatccaaatt aaataattct tcaaaaaact ttatcttttc atgataatct gcaatgtcag
     4681 aaagattatt tttattaaca ctcataacac tagcccctta cttttccgta aactctccgt
     4741 ctacgacgtc atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt
     4801 gttgcgctgc tgcggcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca
     4861 atgcttcaag ttttgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt
     4921 catcaagggc agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct
     4981 tgattgtctt ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt
     5041 ctttacgttt cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt
     5101 cttcgtcagt caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa
     5161 ggtctttggc cttaacagac acgataccgt tcttgtcgat atcaaatgtt acttcgattt
     5221 gaggaattcc acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt
     5281 tatctgctgc cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt
     5341 ctgctgctgt tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa
     5401 gttttgtaaa tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa
     5461 ggacaacatc cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa
     5521 ctacttcatc agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt
     5581 caacaacggc agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca
     5641 agctcaaacc tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt
     5701 cacgagtcaa atcatcaaat ttcgcacgag ttaaagtcat ttccaagtga agaggtccag
     5761 cctcacctgc agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt
     5821 tcttcgcttt ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt
     5881 cgataccgtt ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt
     5941 cgtcaccacc aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca
     6001 attcaaggat agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt
     6061 ctttgtcagt cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac
     6121 gttctacttc aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt
     6181 tgaagtaagc cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag
     6241 cgtagccttt caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc
     6301 catttgcaga aactttttca gaagttccca tcttagattt gatagagata actgtatctg
     6361 ggtttgtgac tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg
     6421 agactacaga tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc
     6481 cttcaagaac tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca
     6541 tgtgtttttc tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg
     6601 cgacgccgtc agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc
     6661 aaaatttgcg caaatagcgc cacggcgaag agtatcgtgt ttggttcgct tcgctcacta
     6721 ttacaaagcc aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt
     6781 ctattatgta aattgcgaca cgaagagtcg aaatcgattt tatttcgacg acgagttagt
     6841 aaggaagcta ggcaaacgcc atagcgattg ccgttttctg acgagttgct ttagctaccg
     6901 tcagaattgc cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg
     6961 ttcatcgaac acttcgtcaa tctcctattt ttactgcgag ctttttacgg gctttgtatc
     7021 ttagttatac accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt
     7081 ttgaaagact tgagcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat
     7141 ggccatatgg tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc
     7201 tttcaaagcg tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt
     7261 caaaccttca actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc
     7321 caagtcctgg ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat
     7381 attttgcatt tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt
     7441 tgccaagtcc aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc
     7501 ttcttgaact tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa
     7561 tgatttcaat cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc
     7621 aacttcatgg tcaaaacacg gttgaccaca ttgatttgat tgattagctg ttggtaatcc
     7681 agattaactg gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta
     7741 ctactaatca ccgctaggtc agctaaacag gactcttgac cgtctgcaat acgaacattt
     7801 tgcatctgat cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca
     7861 aagaactgat aggctgctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca
     7921 atgttttcgt tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt
     7981 gttgtaaagt aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct
     8041 aaaacggtgt gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc
     8101 tgcaagaagt tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta
     8161 aataccgcca aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc
     8221 ctgctcggct caacatccag tgccactacc gtacagccac tcaggtctgt tagcaagtta
     8281 gcagcctctt gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc
     8341 tcatatacct cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga
     8401 aaaccagcaa cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt
     8461 ttttctagtt ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc
     8521 aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa
     8581 atatcctgct gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact
     8641 caatgcatcc aagtgctaac ttatgattct attatacacc cttagaagag aatgtcaaga
     8701 caaaaactca aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct
     8761 agaaccttgc tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag
     8821 ataagaaatc agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc
     8881 tctaaacaaa ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag
     8941 tctagatcgc ataacttccc atttgagccc cttactcata tagacttgat cctctggaag
     9001 taaatcagaa gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc
     9061 tctatctcta aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat
     9121 acggtagatg acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt
     9181 tctatacctc caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc
     9241 aacaatagtg aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa
     9301 aacatgcctg gcgttattta ttagataatt ctttccgctt ttgactcaat ctccaaaaaa
     9361 tataagaaat ctgaatcgca aaaactatca ataaaaccca atctattatg aaagtcaaaa
     9421 acacttccca actgaaagaa ctacctccag tgacaaactt tgagaaaaac ggtagtagag
     9481 ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa aatccttttg gcataaaaaa
     9541 atctttattt aaacgaaaat attatggcaa aatttacgcc agtttttgaa cggctgatgt
     9601 agatatttta tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac
     9661 cagcccgact gaaagtgctt ataaatgata ataagtcgcc tgccgaaaac agcgaaaaat
     9721 agcggtgtta tgcggagata atctgacgcg atgcgaaagt atattgcata cttattttca
     9781 acaatttagc agagtatttt tataagtgtg atataataga agtataattt gttctgatag
     9841 tttattttat ggagaagtag atttttagaa tgcggagggt tcaatatggt tgagtttata
     9901 aagtctaaga aagaaatgag tgaggaggat attaaagcaa atttcatcac tcctgctatt
     9961 gtatccaaag gatggaaaaa tggtgagcat atcgcttacg aagaatactt cactgatggt
    10021 cgaattgagg ttagaggaga taaggctcgt cgtaaagaag gaaaaaaatc agactattca
    10081 ctgtattacc aatttggaac tcgaattgca attgttgagg caaaggataa taaacacagc
    10141 gttcgagcag gattacaaca agctattgaa tatggagaga ttttagatgt tccatttgtt
    10201 tattcttcga atggtgatgg ctttattgaa cacgaccgta tcacgagaga agaacgtgag
    10261 ctggagttag acgaattccc tactcgtgaa gaattatttt ctcgtatgac gaaggaaaaa
    10321 ggattgacgt acgaaattac agaagctatc tcaactccat actatacaga cgccttctca
    10381 atgaaaacgc cacgctatta tcagcaaata gctatcaacc gtactattga aacagttgcc
    10441 agaggacaaa aacgagtaat gtttgtgatg gcaacaggaa cggggaaaac gttcatggct
    10501 tttcaaatta ttcatcgcct tcgaaaagct ggtttggcta aacgagtttt attcttagcg
    10561 gatagaaaca tcttagtaga ccaaacgatg gctgaagact ttaggccatt cgaaaaggta
    10621 atgacgaaaa ttacaccaaa acttttgact gctcctgaaa aattaaattc ttttgaaatt
    10681 tatctagggc tttatcagca actaactggt gaagatggaa ctgaaacaca ttatcaaaaa
    10741 tttgacaaag acttctttga tttaatcgta attgatgaag cgcaccgtgg ttcagctaag
    10801 gaaaacagta actggcgtaa gataattgat tatttcagtt ctgcgacaca gattgggatg
    10861 accgctactc ctaaagaaac caagaatgct tccaatacgg aatactttgg tgagccaatc
    10921 tatacttata gtttaaaaca gggaatcgag gatggttttt tggctccata tcgtgttatg
    10981 agggttaatt tagatgtgga tgtggatggt tatcgtccag aaactggaaa agttgatgct
    11041 aacggacaat taatagaaga taggtactac ggcaggaaag attttgataa aaccattgtc
    11101 attgatgata gaacgcaaag agttgccaag tttgtttctg attatatgaa gcaaaacaat
    11161 gcacgatttg ataaaacaat tgttttttgt gttgatattg accatgccga gcgaatgcgt
    11221 gctgcacttg taaaagagaa tctagactta gtccaagaag actatcgtta tgtcatgcaa
    11281 gtaactggtg acaacgctga aggaaaagct caactggata actttatgga tgtcaattct
    11341 aattttcccg ctatggtaac aacgtctaaa ttattaacga caggagttaa tgctaaaaca
    11401 tgtcgtttga ttgttttaga ctctaatatc caatccatga ctgaatttaa acaaattatt
    11461 ggtcgtggca cacgtcttta tcctcaaaag gggaaagaat tttttacgat tattgatttt
    11521 cgaaatgtta ccaatttgtt tgctgaccct gattttgatg gtgatcctgt gaaggtgctg
    11581 gaaacaggtg cgaaaacagt cagtggttct acgcccggtt tcgtagataa ggaaggtgac
    11641 ccagtagaaa aatatatcgt tacagacaag caggttacca ttcttaattc tactgttcaa
    11701 gtattggatg aaaacgggaa actgattacc gaaagcctga ccgactacac tcggaagaat
    11761 atcttaggta gctacgccac tttgaacgat tttatcacag tttggcatac ggcggataaa
    11821 aagaagctta tcttagacga actttataaa aaaggagttt atctagatgc tattcgagag
    11881 tcggagggaa tatcagaaca agaaatcgat gattttgatt tactcctaaa acttgcctat
    11941 ggtcaaaaag aattaaccaa aacggaacgt atcaataaac tcaaacaaag cggatattta
    12001 tataaatata gtgaggaagc gcgtgctgtt ttggaaattt tactgaacaa atacatggat
    12061 aaaggtattg gagaactcga aagcattgaa acattaaaac ttccagaatt tcagatatat
    12121 ggtggaacct tcaaaatcat caatacttat tttggagata aaaaacgata tttacaagca
    12181 attaaagaat tggagcaaga gctatttaca gtagcttaat gaaaggaaag tatgtcaatt
    12241 acatcatttg taaaaagaat tcaagatatc actcgaaacg atgctggtgt taatggtgat
    12301 gctcaacgta ttgagcaaat gtcttggtta ttattcttaa aaatttatga tagccgtgaa
    12361 atggtttggg aattagaaga agacgagtat gagtcaatta tcccagagga attaaaatgg
    12421 cgaaattggg ctcatgctca aaatggggaa cgggtattga caggcgatga attacttgat
    12481 tttgtcaata acaagttatt caaagagttg aaagagcttg aaataacttc aaatatgcct
    12541 attcgaaaaa cgattgttaa atcagctttt gaagatgcga acaactatat gaaaaatggc
    12601 gtcttgttac gccaagtcat caatgttatt gatgaagttg atttcaatag ccctgaagat
    12661 cgtcattcgt ttaatgatat ttacgaaaaa attcttaaag atattcaaaa tgctgggaac
    12721 tcaggagaat tttatacgcc acgtgcagcg actgatttta ttgccgaagt tcttgaccca
    12781 aaacttggag aatcaatggc agaccttgct tgcggaacag gaggcttctt gacttcgact
    12841 ctgaaccgtt taagtagtca acgtaaaact agtgaagata ccaaaaaata taatacagct
    12901 gtttttggta ttgaaaagaa agcatttcct catcttttag cagttacaaa tctgtttctt
    12961 cacgaaattg atgaccctaa aattgttcat ggaaatactt tggagaaaaa tgttcgtgaa
    13021 tatacgaatg atgaaaaatt tgacattatt atgatgaatc caccttttgg agggtcagaa
    13081 ttagaaacaa taaaaaataa ctttccagca gaattacgga gttctgaaac agctgattta
    13141 tttatggctg tcattatgta tcgtttgaaa gaaaatggtc gtgttggagt tattttacct
    13201 gatggttttc tatttggtga aggtgtaaaa actcgcttga aacaaaaact ggtagatgag
    13261 ttcaacttgc atacgattat taggttgcct catagtgtct ttgcaccgta tacaggaatc
    13321 catacgaaca ttcttttctt tgataaaaca aagaaaacag aagaaacttg gttttatcgt
    13381 ttagatatgc cagatggtta taaaaatttc tcgaaaacta agccgatgaa gtcagaacac
    13441 ttcaatcctg ttcgtgactg gtgggaaaat cgtgaagaga ttctggaagg taagttctac
    13501 aaatctaaat catttacacc tagtgaattg gctgagttga attataattt agaccagtgt
    13561 ggttttccaa aagaggaaga ggaaatctta aatccctttg agttgattca gaattatcaa
    13621 gcggaaagag caactttaaa tcataagatt gataatgtat tagctgatat tttgcagttg
    13681 ttggaggaca aataatgaca ccagaacaac ttaaagcaag tattctccaa agagcgatgg
    13741 aagggaaatt agtgccgcaa aatcccaatg acgaacctgc aagtgaatta ttaaagagaa
    13801 ttaaagctga aaaagaaaaa cttatcagtg aaggaaaaat caaacgagat aaaaaggaaa
    13861 ctgagatatt tcgtggtgat gatg
//
LOCUS       DBERAE010000052        12835 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.52, whole genome shotgun sequence.
ACCESSION   DBERAE010000052 DBERAE010000000
VERSION     DBERAE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.52"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(132..1334)
                     /gene="rpsA"
                     /locus_tag="ACL70N_001883"
     CDS             complement(132..1334)
                     /gene="rpsA"
                     /locus_tag="ACL70N_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGS0590631.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1496..1567)
                     /locus_tag="ACL70N_001884"
     tRNA            complement(1496..1567)
                     /locus_tag="ACL70N_001884"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1533..1535),aa:Gln,seq:ttg)
     gene            complement(1577..1657)
                     /locus_tag="ACL70N_001885"
     tRNA            complement(1577..1657)
                     /locus_tag="ACL70N_001885"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1621..1623),aa:Tyr,seq:gta)
     gene            complement(1707..1937)
                     /locus_tag="ACL70N_001886"
     CDS             complement(1707..1937)
                     /locus_tag="ACL70N_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGS0590632.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2105..2749)
                     /gene="pcp"
                     /locus_tag="ACL70N_001887"
     CDS             complement(2105..2749)
                     /gene="pcp"
                     /locus_tag="ACL70N_001887"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS0590633.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2764..3687)
                     /locus_tag="ACL70N_001888"
     CDS             complement(2764..3687)
                     /locus_tag="ACL70N_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGS0590634.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3684..4373)
                     /locus_tag="ACL70N_001889"
     CDS             complement(3684..4373)
                     /locus_tag="ACL70N_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGS0590635.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4438..5116)
                     /locus_tag="ACL70N_001890"
                     /pseudo
     CDS             complement(4438..5116)
                     /locus_tag="ACL70N_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
     gene            complement(5172..6194)
                     /locus_tag="ACL70N_001891"
     CDS             complement(5172..6194)
                     /locus_tag="ACL70N_001891"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGS0590636.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGSVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6324..8795)
                     /gene="parC"
                     /locus_tag="ACL70N_001892"
     CDS             complement(6324..8795)
                     /gene="parC"
                     /locus_tag="ACL70N_001892"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGS0590637.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(8996..9200)
                     /locus_tag="ACL70N_001893"
                     /pseudo
     CDS             complement(8996..9200)
                     /locus_tag="ACL70N_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9215..11158)
                     /gene="parE"
                     /locus_tag="ACL70N_001894"
     CDS             complement(9215..11158)
                     /gene="parE"
                     /locus_tag="ACL70N_001894"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGS0590638.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRSDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11294..11935
                     /gene="plsY"
                     /locus_tag="ACL70N_001895"
     CDS             11294..11935
                     /gene="plsY"
                     /locus_tag="ACL70N_001895"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGS0590639.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(11980..>12835)
                     /locus_tag="ACL70N_001896"
     CDS             complement(11980..>12835)
                     /locus_tag="ACL70N_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0590640.1"
                     /translation="TEIVQELMTEFSLVLLLKSIKLARWTYYYHLKQLDKTDKDQELK
                     AEIQSIFIEHKGNYAYRRVHLELRNRAYLVNHKRVQGLIKVLNLQAKMRQKRKYSSHK
                     GDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNL
                     STSPNLEQVQTMLEQVFTEKHYENTILHSDQGWQYRHDSYHRFLESKGIQASMSRKGN
                     SPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYVDYYNNKRIKVKLKGLSPV
                     QYRTKSFG"
BASE COUNT         3693 a         2890 c         2258 g         3994 t
ORIGIN      
        1 acttcaaccc actacagttg acaaagagcc cctttctcga gcttagcttt tcttcaaccc
       61 actacagttg acaaagagcc agaaaaatcc cttgtttagt aaacaaagga ttttgtgaat
      121 tttcaatttg attaaagttc gatgtcacca aacaaatcag ccattgaaaa tcctgtttgt
      181 gtttctggaa gttcgaaatc acgcttttct tgacgtcttg gacgacgtgg acgagcagca
      241 cgtttttctt ctttttgtcc ttcttcttgg gctggacgtt cttcaagagc tttaatagaa
      301 agtgacacgc gttctgcatc tgcgttaact tcaagaactt taacttgaac ttcttgacca
      361 actttaagag cttcttttgg attttcaatc cgtttgtgtg aaatttgtga tacgtgaaca
      421 agtccatcga tacctggcaa tacttcaaca aatgcaccga agtcagtcaa acgtttaact
      481 gttccttcta ctacatcacc tttagccaat ttttgctcaa cgccatccca tggtcctggt
      541 actgttgctt taagtgaaag tgatacacgt ccttcttctt cgttaagatc aaggattttc
      601 acttcaattt cttcaccaac agttacaact gattttggtg atacgttacg ttcatgtgac
      661 aattcagtca agtgaaccaa tccgtcaaca ccaccaaggt cgacgaaagc gccgaagctt
      721 gtgatacgag caactttacc agttacaaca tcaccaacag ccaatttacc gaatacttca
      781 gcgcgagctg ctgcagtagc tgcttcaaca acttcacgac gtgaaaggat gaagcggttt
      841 tctttagcgt taacttcttt gattttagta tcaaattctt gacctacaaa acgctcagca
      901 ttacgtacga aacgagtatc caacattgaa gctgggataa atccacgaac accttcaaat
      961 tctactgaaa gtccaccttt aacggcacgc gttcctttaa cagtaacaac ttcttcttcg
     1021 cgaccaacaa gtttgtccca tgctttgcga gcttcaaggc gttttttaga tacaaggtat
     1081 gtaactgtat cagtatcttt accaactact tgacgaagta caagaacatc caatacttct
     1141 cctactttaa caaagtcatt gatatctgca tcacgatcgt ttgtcaattc gcgaagagtc
     1201 aagacacctt caacaccagt tccagagatt gcaacgttag cttgagtcgc atcaactgtc
     1261 aatacttcag cactaacaac atcaccagtc tcaacttgac taacgctatt tagcaaatct
     1321 tcaaattcat tcatctaaaa aatcctccaa caatcaagtt tttcttaaac ttgacatact
     1381 tataattttt ttcctaagca cccgcaagga catgttcata tcattcacgt ctttcaatta
     1441 taaaaataaa ataccctaag atattttgct ttttatcttg attattacct aagaactggg
     1501 gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc cttgccttac cgcttggcta
     1561 taccccatta atgaaatgga gagagaggga ttcgaacccc cgaacccgaa ggagcggatt
     1621 tacagtccgc cgcgtttagc ctcttcgcta tctctcctac aatcaacatg gactattata
     1681 tcatgaaaat ttcaaaaaaa caagacttat tttgctaaat tataattttc aatcaaaatt
     1741 tccacagctt tttccaattt tttataaaaa ctatcgacat tcccattctt tataatggca
     1801 aattgtccgt ctaattcggc aatttctccg ataacttttt taccgatagt caatgtataa
     1861 ccttcaaaac tgtctttacc aacattaact ttggcatccg ctacttgaat ttcgattttt
     1921 ttatctttct tgctcatttc atacctctct tcactttttc tattttacaa gaaaattcta
     1981 aaactagcaa gaaaaaactc tatatcaggc ttctctgata tagagtttta tgtaaacaac
     2041 ctcaattgat ttagcatagt taatagttag taaacaagca taattgacta tcctttttag
     2101 gttatcagtg agtctcaccg cctactaact gcaaatcctt atctttgtag tctacaatag
     2161 cttcaatagc tacctctatg cctcttacaa tatcacatag actcattcct gcagtattcg
     2221 gcttatttac tacttgttcc atcatatatg gaatatgcat gaaacctgct ctcatattag
     2281 ggaatttttt atccactaaa taaagagctt ggtacatcaa atgattgcaa acaaaggttc
     2341 ctgcactatt ggatacaact gccggaagtc cctgtttttt gatagcttgt accatcgctt
     2401 tgataggtaa actactaaaa taggccgatg ctccatcaat acgaatcggt gtatcaattg
     2461 gttgattgcc ttcgttatca ggtatgcgag catcatcttg attaatagcc actcgttcag
     2521 gtgttaagcc ggtcctgccg cctgcttgtc caatacaaag tacagcatct ggttgatatc
     2581 gtaatatttc tgcctctaaa acttctgacg acttataaaa aaccgttgga atttctaccc
     2641 agcgaacttc agccccatta atctcagatg gtaataattt tacagcctcc aaagctggat
     2701 taatcttttc acctccaaaa ggattaaaac ctgtaaccaa tattttcatt ttattttcct
     2761 ttactaaaat gcgagaaagt acattaagaa tatgtgaata acaatcatta ctagagcaac
     2821 acctgcttga gcctttataa cgccattctg atctttcata tccatcaatg ctgctggtag
     2881 agcgttaaaa ttagcagcca ttggggtcaa taaggtccca caataacctg ctgtcatggc
     2941 aagagcacca gccacaattg gattagctcc cagagcaaat acaaagggaa ctccaacacc
     3001 tgctgtaata acggtgaatg ctgcaaaagc atttcccata atcattgtga atagaaccat
     3061 tccaagaaca taggccaaaa ctcctataaa gcgactatct gaaggaacaa taccgctaat
     3121 cagatgagag ataacatcac caacacctgc tacagtaaaa atagccccca aagcccctaa
     3181 taattgagga acaataccac ttgttgaaac ttgctgagtc attcgattat tttctgataa
     3241 cagactctta gggtgactat tggtaatcac aagaacagaa attgtagcaa acaaggcggc
     3301 aaggctaatc gaaatcttgc taaattctgg aatcatttgc gctaagacca acgcaagtat
     3361 tgccatcagc ataactggaa taaaaatttt atttttcaac ctgttagatt caatattggc
     3421 tttcatttca tctaaggatg gcaaggttcc gatacggact tgcttaaaca atgttaacag
     3481 cgataatagg attacaataa taccaatact catatttggc atataggaac cacctataaa
     3541 cgtaatagac aatagagtcc aaaatgcaga tgtcccaagt cgaactgggt ttgttttatc
     3601 tttataacta caataggctg tatggagaaa ttgacaacca atcacaatat aggtcaactc
     3661 taatagttgc tttgccaact ctgtcatttt tgttctcctc ccctagtctt ttttgatatc
     3721 aattttttat caaataaata attgtaaatc cccactacaa taagtgttat aacagcaaca
     3781 ataatagatg tagaagcaat ccctgcataa ttgctttcat agcctaactg atctaatgtt
     3841 ccccctatca agaggactcc cccagcacct acaaacgtat tttgagcaaa gaaatttcca
     3901 aaattttcat tcgcagccgc acgcgctttt attgtctcat cttcaacctc tgttaacttt
     3961 ctacctaatt gagactctgc agctgcttct cccataggtt gaaccaaagg tctgacaaac
     4021 tgagggtgtc ctcctagacg aattgaaaag aaaccagcta actctcgaat aaagaaataa
     4081 actgtataga agtttccaac tgtcagacct ttaatctttc gaatcaaatc gattgatcgt
     4141 tgcttgagtc caaaggtttc tgacagcccc acaagaggca aggtaaccat aaaaatcgtg
     4201 agcactcgct gattgctaaa ttcttttccc aaaatctcca aaaattcaac gagagaaaca
     4261 cctgaaacta aagctgtaac caaaccagct aagactactg ttgcaattgt atcaaatttt
     4321 aaaataaaac ccacaacaat gattgctatt cctattaatc taatccactc catatcaaac
     4381 tcctttatat tcaaaatgac agtattttaa aaattttatc aagatcaata ccattcctta
     4441 tttaatgtat ttttctagtt ctttttggta tttgccattt tttaaaaacc tcgttatatt
     4501 cttttgttgt aacaatatct ttttgcaatt tcattccttt aaagatatat ggatccccct
     4561 taataccaac ttgtgagtat ggttttgaga atggtactac gttacttaca actggagaac
     4621 caccagatga agctgttggc atcaataatg aactatctgt cgaccaagct tgagctttgg
     4681 catatttttc atatctcttc tctaggtcag tggtctcaga aacagcatct tctaacaatt
     4741 tcttatattt atccaaacca ggtttagcta caacatcctt atcttttcct ttcgtaatac
     4801 caaggtgttt catggcaaaa ccagattttg gatccataat attcaagtaa gacgctggat
     4861 cttgatagct tggagcccat cctgtactat tcaaatcata gtctttttga gaaggagcaa
     4921 cattgccgta tttatcattt tccatcaaac catcaataac atttccaata acgtctgtcg
     4981 tcgatgttcg agtcgctata ctgtagccca atgatgctgg atctactgca tagacataag
     5041 aaaatgttgt cggtgcatcg gcttctttat cagtttttcc acaagccact aaaatagctg
     5101 acgtgctcag gaccactcct gctgttaaga gccacttttt ctatttcata aaaaatctcc
     5161 ttcggtttat tttaatctac ttttacaatc caaccttctg gcgcttcaat atcgccaaac
     5221 tgaatacccg tcaattcatt atataattta cgcgtcacag aacctacttc tgtttcacta
     5281 tagaatacat ggaaatcatc accatgttga atacctccaa ttggagaaat aaccgctgct
     5341 gtaccacagg cacctgcctc tacaaaacgg tcaagattat caattggaac atcaccctca
     5401 ataggagtta atcccaagcg gtgttctgcc aaataaagca aggaatactt ggtaatagat
     5461 ggcaagatag atggactcaa tggtgttaca aattcattat cagctgtaat tccaaagaaa
     5521 ttagctgatc cgacttcttc aatctttgta tgagttgatg ggtccagata gataacatct
     5581 gagaaatggc gtgacttggc catttttcct ggtaagagac ttgcagcata gtttccacca
     5641 accttagccg cacctgtacc atttggtgct gcacggtcgt actcatcctg aatcaagaag
     5701 ttggttggga ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa gatggtgaaa
     5761 atgtactctt ctgccggttt taccccgata atatctccga caccaatcaa aagagggcga
     5821 agatataagg ttccacctat tccgtatggt ggtacgtatt cttcattcgc acggacaact
     5881 gctttacaag cttctacaaa catgtctgtc ggaacttgtg gcatcaagag acggtcacat
     5941 gtacgttgca ggcgtttagc attttcatca ggacggaaca gttgaacact gccatcctta
     6001 gtacgataag ctttcaaacc ttcaaatgct tgttgtccat agtgaagact tggagaagac
     6061 tctgaaatat gcaaagttgc atcctctgta agctctcctt gatcccattg tccatttttg
     6121 aaatgagcaa gatagcgata aggtaatttc atataggaaa aaccgaggtt ttcccaatca
     6181 atcgttactg tcatattcca ctccttattc taaaaaccta tttcttatat tctacactat
     6241 ttttctaaaa tagcaagtat attttgtaat tttcagaaaa ttcctccaat aaaaaccatc
     6301 ttagaactga ttcttcattt cacttattta tcttcagtaa ctacttcctg aagataagcg
     6361 tcaaaaactt cttcatctga aatcgtgtca gaaatgaagc ttccattgct agtgcgttct
     6421 gacaagttca agtcttgcaa tcggctttca tagattgttc ctttattgga ttggacaagc
     6481 agagtttggt cgttcacatc cacttccgta ctgaagaaat cgccaacaaa tccttgctct
     6541 gcaactgctc ctgccaagaa gacacgatgc ggtttgtttt tcaactcacg caagacttgt
     6601 aatcctcgtt tggcacggct ggttgctaga atttcctcaa tggaaacacg tttcaagctt
     6661 ccacgctggg tcaagaggta gaaggacgaa gtattacaga taaagccaga ttggaggaca
     6721 tcatcttctt tcaaattcat agccttgaca cctgctgcct tagcaccgac aaccggaacc
     6781 tcttcgatat tgaaacgcag ggcataacca ttttgactaa ccaagacaac atcatctagt
     6841 ttaatcggag ccactgctac aatctgatct gtatcgtctt tgagcttagc atacttgaca
     6901 gacttagatc tataggtccg ccatggagtg aattcttttc gctctacccg tttgatttga
     6961 ccaaggcgag tcgctgcaaa gtaggttgtc gcatcgtcaa actgatccag tacttccaca
     7021 taaaggattt cttcattcgt ttcaaagttt gtgatggttt ggctcagatg ctctccgatg
     7081 tccttccaac gaatatctgc caactcatgg attggtctgt agatgacatt tccaagactt
     7141 gtgaacatca agaggtgctg ggttgtcttg gcagattgaa caaaaatcaa acggtcatca
     7201 tcacgcttgc caatttcttc caaggtggaa gccgcaaagg aacgtggact ggtacgcttg
     7261 atgtaacctg ccttggtcac gctgacgtag gtatcttcct cagcgataag actagctgta
     7321 tcaatctcaa ttgctttcgc agtgtcttct aaagaactca aacgaggagt tgcaaatttc
     7381 ttcttgacct cacgaagttc tttcttcatg agattgtaca tagtcctttc atcaccaata
     7441 atagccgcca gcatagcaat cttctcacga agctctgctt cttcttcctg caagacaacc
     7501 acatcggtat tggtcaaacg gtacagttgc aaagttacga tagcctcagc ctgttcttcc
     7561 gtaaaatcat agctaacttt gaggttttcc ttggcgtccg ccttattctc agaagcacgg
     7621 ataagagcaa tgacttcatc caaaatcgaa atcacacgaa tcaaaccttc gacgatatgg
     7681 agacgtttct cagccttttc tttgtcaaag cgtgaacgcg ccaaaatcac ttctcgacgg
     7741 tgagcgatgt agctagacag gattggaaca atcccaacct gacgaggtgt gaaattgtca
     7801 atcgccacca tattaaagtt gtagttgatt tgtaggtcgg tgtacttaaa taagtagttg
     7861 agaacaagct cagtattagc gtctttctta agttcgatag cgatacgaag accatcacgg
     7921 tcagactcat cacgaacctc agcaatccca gctaccttgt tattaacacg aacatcatcg
     7981 attttcttga ctagattggc cttattgatt tcataaggaa tctcagtaat aacgatttgt
     8041 tccttaccac cttttagctt ttcaatttca gtcttggaac gaacaaccac gcgccctttc
     8101 ccagtctcat aagctttctt gatttcatca cgaccctgaa taatagcccc tgtagggaag
     8161 tctggtccag gcaagaattc catgagttta tcaatctttg cagttgggtg gtcaatcatg
     8221 taaactgcag catctatgac ctcagctaaa ttatggggag gaatgtctgt ggcataacca
     8281 gccgaaatcc cagtcgaacc attgaccaag aggtttggaa aggctgctgg caagaccgtt
     8341 ggttctttct ccgtatcgtc aaagttccat gcaaaaggaa ctgtcttttt ctcgatatcc
     8401 tgaagaaggt agcctgcaat ttcagacaaa cgtgcctcag tataacgcat agccgcagga
     8461 ggatctccgt ccatagaacc gttattaccg tgcatttcaa ctagaatctc acgatttttc
     8521 cagttctgtg acatacgaac catggcatca tagatagaag aatccccgtg tgggtggaaa
     8581 ttccccatga tgttcccgac tgacttggcc gacttacggt agctcttgtc aaaagtattg
     8641 ctatccttat tcatagaata aagaatacgg cgctgaaccg gcttcaaccc atcacgaata
     8701 tctggcaaag cccggtcttg aataatgtac ttggagtagc gaccaaagcg ctctcccatg
     8761 atgtcctcca gggacatgtt ttgaatgtta gacataagat acaaagccca taaaatacca
     8821 agtgaaaata gaaaattctt gaagtaagca aactcacaag agaatttatc tttttcacac
     8881 aatatctagg gcgtgttcaa ctcctttcaa agaatgtaga gtaggttttt atgcagtaaa
     8941 agatatttta cgggaattcg tcccgtgttc agttacgata agtaaccaaa ctatcctgtt
     9001 tgtatttttc aatatgaaaa tctggttttc caaaattagt cttagtttgt gtcttagccg
     9061 ctcccttaaa cgcctctttg agataagcac tcatagaaga ttcttcatta ataattctgc
     9121 aattttttca aaccaagatt ttcaaactgc tttttcacat agtcattcac atccgactct
     9181 aatttccagt ttactaacat attattttct ttcattaaaa cactgtcgct tcttctagcg
     9241 taaacttgac attatcttca atccatttac ggcgtggttc taccttatct cccatgagaa
     9301 cattgacgcg acgttcggcg cgcgctaaat cttcaattgt gacacggatg agggtacgtg
     9361 tttctgggtt catggttgtt tcccagagct ggtccgcatt catctcacca agtcctttgt
     9421 atcgttggag ggtagcgcct ttaccgaact gtttacgtag ttcttctagt tctccgtccg
     9481 tccaagcgta ggccacttct tctttcttgc ctttaccttt ggacatcttg taaagaggtg
     9541 ggagggcaat atagacatga cctgcctcga ctagcggacg catgtaacgg tagaaaaatg
     9601 tcaagagcaa ggtctggata tgggcaccgt cggtatccgc atcggtcatg ataatgatct
     9661 tatcatagtt ggcatcttca atagagaagt ctgctccaac acccgcacca atggtataaa
     9721 tcatggtatt gatctcttca tttttgagga tatccgccat cttggccttg gctgtattga
     9781 taaccttacc acgaagaggt agaatagcct ggaacttgcg gtcacgacct tgtttggcag
     9841 aaccaccggc agagtccccc tcaactagat agagttcatt cttagcagga ttcttagatt
     9901 gggctggggt caatttccca gacaacaagc ccttatcttt cttgtttttc ttcccatttc
     9961 ggctctcatc acgcgcctta cgtgctgctt cacgagcatc acgggccttg atagccttgc
    10021 ggatgaggtt agaagctaat tccccatttt ccataaggaa aaaggtcaac ttatcagcca
    10081 ctattccatc cacaactggg cgagctaagg ggcttcctag tttatccttg gtctgtcctt
    10141 caaactgcaa gtgttcttca ggaactaaga tagaaagaac ggccgctagt ccctcacgat
    10201 agtctgaacc ttcaaggttt ttatcttttt ccttgagaag acctgtttta cgtgcatagt
    10261 cattcatgac cttggtaatg gcagacttga gtcctgtctc gtgcgttcca ccgtccttgg
    10321 tgcgaacgtt attgacaaag gatagaatgt tatctgagaa tccgtcattg tactggaggg
    10381 ctacttccac ttgaaaacca ttgtcttccc cttcaaagta aagaactggc gtcaagattt
    10441 ccttatcttc gttgagataa gaaacaaaat cttgtactcc attctcatag tggaactcaa
    10501 tcgcttcatc tgatcgcttg tccgttaaag acaaggtcac atttttcaag agaaaggctg
    10561 attcattaag gcgctctgaa atggtattgt acttgaaatc tgtcgtagaa aagatagtcg
    10621 cgtcaggcat aaaagtaact ttggtgcctg ttttagactt gggtgctgta ccgactttct
    10681 tcaaagtcgt gacaggtttt ccaccatttt caaaacgttg cttgtaaact gcgccatcac
    10741 gggtaatttc aacttctaac cagctagaaa gggcgttaac aacggaagaa cccactccgt
    10801 gaagtccacc tgatgtctta tagccacctt gaccgaattt ccctccggca tgaagaatgg
    10861 taaagataac ctcaacagtt ggaattccca tagcgtgcat acctgtcggc atcccacgtc
    10921 catggtcttg aaccgttaga ctaccgtctt tattgatagt tacatcaata cgatcaccaa
    10981 acccagacaa ggcttcatcg actgcattat caacgatttc ccaaactagg tgatgaagac
    11041 cagcgccatc ggtcgatcca atatacatcc ctggacgttt tcggaccgca tccaaccctt
    11101 ctagcacctg aatagcatca tcattataat tgttaatatt gatttccttt tttgacacaa
    11161 ggaacctcct attcgttcat ctttactatt ctacaggttt tccaaggatt ttgcaaaatt
    11221 tttctttctc cgatgtgaca atttcagcag agattctctg cttttctttc ccaattcatg
    11281 atataatagg agtatgatta caataatttt attaatccta gcctatctgc tgggttcgat
    11341 tccatctggt ctctggattg gacaagtatt ctttcaaatc aatctacgcg agcatggttc
    11401 tggtaacact ggaacgacca ataccttccg cattttaggt aagaaagctg gtatggcaac
    11461 ctttgtgatt gactttttca aaggaaccct agcaacgctg cttccgatta tttttcatct
    11521 acaaggcgtt tctcctctca tctttggact tttggctgtt atcggccata ccttccctat
    11581 ctttgcagga tttaaaggtg gtaaggctgt cgcaaccagt gctggagtga ttttcggatt
    11641 tgcgcctatc ttctgtctct accttgcgat tatcttcttt ggagctctct atcttggcag
    11701 tatgatttca ctgtctagtg tcacagcatc gatcgcggct gttatcgggg ttctgctctt
    11761 tccacttttt ggttttatcc tgagtaacta tgactctctc ttcatcgcta ttatcttagc
    11821 acttgctagt ttgattatca ttcgtcataa ggacaatata gctcgtatca aaaataaaac
    11881 tgaaaatttg gtcccttggg gattgaacct aacccatcaa gatcctaaaa aataaaatgc
    11941 cagttctgtg aactgccccc caaaagttag acaaataatt tatccaaagg atttagttct
    12001 gtactgcaca ggactaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc
    12061 aacatagtct acaatagctt gttccaattg cttaagcgac tgaaacgact tctcataacc
    12121 gtaaaacatt tccgatttca gaatcccaaa gaaggactcc atcataccat tgtctgggct
    12181 gttaccctta cgtgacatag atgcttgaat tcccttactc tctaggaacc gatgataaga
    12241 atcgtgtcgg tattgccagc cttggtcact atggagaatc gtattctcat agtgcttctc
    12301 tgtgaatacc tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt
    12361 ataggcgata atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt
    12421 acttgctgga atggcaaatt ctgtcacatc tgtgtagcac ttttccattg ttttagagcc
    12481 ttcaaattgg ccttgaatga gattctctgc tttcttacca acgtctcctt tatgagaaga
    12541 atattttcgt ttctgtcgca ttttagcttg taaattgagt acttttatca agccttgaac
    12601 tcttttatga tttaccagat aagcacgatt tcttagttct aaatgaaccc ggcgataagc
    12661 ataatttcct ttgtgttcga taaagatgga ttgaatttca gctttaagct cttggtcctt
    12721 atctgttttg tctagctgtt tcaagtgata gtagtaggtc caacgagcta gtttaatgga
    12781 ttttagaaga agaactaacg aaaactcagt cattaattct tgaacaattt ctgtc
//
LOCUS       DBERAE010000053        12217 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.53, whole genome shotgun sequence.
ACCESSION   DBERAE010000053 DBERAE010000000
VERSION     DBERAE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.53"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(220..2478)
                     /locus_tag="ACL70N_001897"
     CDS             complement(220..2478)
                     /locus_tag="ACL70N_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0590641.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2707..2937)
                     /locus_tag="ACL70N_001898"
     CDS             complement(2707..2937)
                     /locus_tag="ACL70N_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGS0590642.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3127..3810
                     /locus_tag="ACL70N_001899"
     CDS             3127..3810
                     /locus_tag="ACL70N_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0590643.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3810..4544
                     /locus_tag="ACL70N_001900"
     CDS             3810..4544
                     /locus_tag="ACL70N_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0590644.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4698..5555
                     /locus_tag="ACL70N_001901"
     CDS             4698..5555
                     /locus_tag="ACL70N_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGS0590645.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAMDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5697..6569
                     /locus_tag="ACL70N_001902"
     CDS             5697..6569
                     /locus_tag="ACL70N_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGS0590646.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6851..7534
                     /gene="rpiA"
                     /locus_tag="ACL70N_001903"
     CDS             6851..7534
                     /gene="rpiA"
                     /locus_tag="ACL70N_001903"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGS0590647.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7548..8759
                     /locus_tag="ACL70N_001904"
     CDS             7548..8759
                     /locus_tag="ACL70N_001904"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGS0590648.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8761..9303
                     /locus_tag="ACL70N_001905"
     CDS             8761..9303
                     /locus_tag="ACL70N_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGS0590649.1"
                     /translation="MTRYSLLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9319..10128
                     /locus_tag="ACL70N_001906"
     CDS             9319..10128
                     /locus_tag="ACL70N_001906"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS0590650.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGGFKGLLKAILAEL"
     gene            10604..10999
                     /locus_tag="ACL70N_001907"
     CDS             10604..10999
                     /locus_tag="ACL70N_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGS0590651.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11009..11584
                     /locus_tag="ACL70N_001908"
     CDS             11009..11584
                     /locus_tag="ACL70N_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGS0590652.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11609..12120
                     /locus_tag="ACL70N_001909"
                     /pseudo
     CDS             11609..12120
                     /locus_tag="ACL70N_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
BASE COUNT         3608 a         2235 c         2766 g         3608 t
ORIGIN      
        1 tgttcttgtt tcaattgact atagcagatt gaaatgagaa caaatcgatt gggaaagtaa
       61 aattaatttc tataaatgtt ttagcaattg tttcgtacta tttcagattc agtctactat
      121 atatcataat ggacaaaggg caagctgtca agaaattaca gttattttag taaaaaaaga
      181 agcagaaaaa tttcattttc tactcctttt ctataggatt tatttttctt tttcagaact
      241 tttaacttca gcttttttgg cagatttaat ctgaatgttt cccttgctag tcataactgc
      301 tttgagatct ttttcgcttg gattttcaag gtagtagtca gtgattgtgt cctcaatata
      361 gtcttgaata gtccgacgaa gtgggcgtgc tcccattttt ggatcataac ctaggtcaac
      421 caacttttcc ttgaccttat cagttacatc caaacgaatg ttgttgctag agaggcgctt
      481 gttaacatct gctagcatga gctcgacaat ctgaaggagg ttatccttgc tgagagcctt
      541 aaattcgata atgccatcaa aacggttcat aaactctggg ctaaagaagt taccgagttc
      601 accgaggaca gaattggtac gtccttctct agcagcacca aatccaacgc tagcttcggt
      661 ctttcctgta cctgcatttg aggtcatgat aatgatggca tccttgaagc taacggtgcg
      721 tccttgcccg tctgtcaaac gaccatcgtc caagacttga agaaacatgt gcataacatc
      781 tgggtgagct ttttccactt catcgagaag gatgagagaa tatggattgt ggcgaacttt
      841 ttcagttaat tgaccagcct catcatagcc aacataacct ggaggggcgc cgaccaactt
      901 agccacacta tgtttttcca tgtattcact catatcaaag cgaatcatac tatcagcaga
      961 accaaaaagt tcgatagcca gttgtttgga aagttctgtc ttaccgacac cagttggccc
     1021 aacgaagagg aagcttccga ttgggcggtt aggggtacca agtccgacac gattacggcg
     1081 aatagccttg gcaatcttat cgactgcatc atcttggcca ataacatgag acttgagatc
     1141 ttcggctaga tggatgagtt gagattgttc tttctctttc aaatcaccaa cagggatatt
     1201 ggttttctgc tcgataatgt gctcaatagt tttctcgctg atgataggag tatcctggtc
     1261 tgtgatcttt ttcttttgca tttccttata cttggcaatc tggtcgcgga agtaggccgc
     1321 cttctcaaaa tcttcttctc gtgtagcttg agacttgaga ttttcagcct caatcaagcg
     1381 ctgatcaatt actttaggat ccacaaaatt caaggtcaag ttcatcttag aaccagcttc
     1441 atctaggagg tcaatggcct tgtcaggcaa gaagcgatct tggatgtagc gattggaaag
     1501 agttgcagct gcttcaatcg cagcatcggt atattgaacg tggtggtaat cttcgtattt
     1561 cttttgaatc cctttgagaa tagtgattgt ttcgtccacc gttggttcat cgactttaac
     1621 aggctgcata cgacgctcga gggcagcatc cttttcaatg atacggtatt cattgagggt
     1681 agtagcaccg actagttgca gttctccacg agcaagggct ggcttgagga tatttcctgc
     1741 gtccatatta ccatcactcg cagaaccagc accaacaatt tcatggattt catcgataaa
     1801 gaggatgatg tcttcacgtt tgcgaatttc ttccatgagt ttttgcatgc gttcttcaaa
     1861 ttgtcctcga atccccgttc cttgaactaa gctaaccaca tccagacgga tgacttgttt
     1921 accttggagt ttatgtggca catcgccatc gacaattttc tgagctagac cttcgacaac
     1981 ggccgttttt ccgacaccag gttcaccgat aaggacagga ttattcttgg ttctacgatt
     2041 gagaatctcg atgacacgga taatctcatc gtcgcgccca ataacggggt caatgtctcc
     2101 acgacgggca atttcagtta cattaatacc aaattcttcc agcaggcctt tttcttggct
     2161 aggtggcgga gtttgagcag atccacgatt ttgggaacca taaccgccgt ttccaccgta
     2221 acctccacct gattgggttg ggggaatagg aggagtattg ctagaaggtc tgaaattgtt
     2281 tagatcattg aagaaatcac caaagggatc gaagtcacga ttgttcagat ccgtcatacc
     2341 tttgaagagg ctattgttag gatctgtttt gataatctta tagcagtttt gacagaggtc
     2401 aatttgtttt tgttttccat tgagattggt gtaaagatga attgttgagt cgttaatttt
     2461 acagttttga caaagcatac atctacctca tttctttctt tagcctgact tgtttaaagg
     2521 tcaaaaatag tcaaattcta tactctcatt ataacaggat tggggtgtaa agcaagtaaa
     2581 aagattgaag ctttgagaag ttgttacaat gaaaattttt gtgaatttgg actataaaaa
     2641 aatcctattt gtgagacaaa aaggatttta cttagacatg cagggacaat cccagcttgt
     2701 tttagattag tagagaagtt cgtaaatttc cattgcgatt aagtcaatgc tatcaaacgt
     2761 atacgtttcg cgatcttcta cgtcacgaag ggtaaagatt gggccgtttt cttcgtcgtg
     2821 gctgtacgca acttctgcaa caacaactcc ttcgcgttca aaattacgtt ttaaatttcc
     2881 gccatcgttt gccattgctt caaggcggtt gatgattcta accaaatgtg attccatttt
     2941 gattctcctt catttcttat cgttactatt ttaccataaa ggaggccaac ttgactagaa
     3001 aaaactaaga tttctcacta attctgctag tttaaagatt tttaaataaa ttggataaaa
     3061 gatttaaatt ttaattcaaa acatgttata atcatacagt attctatttt agaaagcagt
     3121 gtgactatga atttttcttt tttacctaag tatttacctt attttaacta tggggctgtt
     3181 gtgacgattc ttatttctat ctgtgttatc tttttgggaa ctattttggg tgttgtcttg
     3241 gcttttgggc aacgttcaaa gtttaaaccg cttgtttggt tggccaactt gtacgtttgg
     3301 attttccgtg ggacaccgat gatggttcaa attatgattg cctttgctct tatgcatatc
     3361 aatgctccga ctattcagat tggaatttta ggtgttgatt tttcgcgtct gattccaggg
     3421 attttgatta tctctatgaa tagtggtgct tatgtttcgg agactgttcg tgccggaatc
     3481 aatgcggttc caaaaggtca gctagaggcg gcttattcgc tagggattcg tcctaaaaat
     3541 gcgatgcgtt atgtgatttt gccacaagca gtcaaaaata tcttgccagc attggggaac
     3601 gaatttatca ccattatcaa ggacagctcc ctcttatcag ctattggggt catggagttg
     3661 tggaatgggg ctacaacagt ttctacaaca acctatctac ctttaacacc acttttattt
     3721 gcagcatttt actacttgat tatgacctct attctgacag tagccttgaa agcttttgaa
     3781 aaacatatgg gacaaggaga taagaaataa tgacagaaac cttgataaaa attgaaaatt
     3841 tacataaatc ttttggaaag aatgaagtat tgaagggcat caacctcgag attaaaagag
     3901 gagaagttgt cgttatcatc ggtccttcag ggagtgggaa atctaccttg cttcgctcta
     3961 tgaatttgtt ggaggaagca accaagggga agcttatctt tgagggagtc gatattacgg
     4021 acaagaagaa tgacctgttt gccatgcgtg agaagatggg catggttttc caacaattta
     4081 acctctttcc taatatgact gtgatggaaa atattacctt gtcacctatc aagactaaag
     4141 gtgaaagcag ggaagttgct gagaagagag cccaagagct tttggaaaaa gttggtttgc
     4201 cagataaggc agacgcttat ccacagagtc tgtcgggtgg gcaacaacaa cggattgcca
     4261 tcgcgcgtgg gttggctatg gaaccagatg ttttgctctt tgacgaacca acttcagcct
     4321 tggatcctga aatggtaggt gaggtattgg ctgttatgca agaccttgcc aagtcaggga
     4381 tgactatggt tatcgtaaca catgagatgg gatttgcccg tgaggtggca gatcgtgtta
     4441 tctttatggc agacggtgtg gttgttgaag atgggacacc tgagcagatt tttgaacaaa
     4501 cccaagaaca acggactaaa gatttcttga gtaaggtttt ataatctatt ttaaaatttc
     4561 aagacaagat tagtgaaaag ttcaaccaga gctttttctt atagtttgaa actataggat
     4621 aacctaggaa agaagtgtta gagggcacta gcagtttttg gtataatgga agatatttga
     4681 aagaaaagag aagtgatatg acacagatta ttgatgggaa agctttagcg gccaaattgc
     4741 aggggcagtt ggctgaaaag actgcaaaat taaaggaaga aacaggtcta gtgcctggtt
     4801 tggtagtgat tttggttggg gataatccag ccagccaagt ctacgttcgc aacaaggaga
     4861 ggtcagctct tgcggctggt tcccgtagcg aagtagtgcg agttccagag accattactc
     4921 aagaggaatt gttagacctg attgctaaat ataatcagga tccagcttgg catgggattt
     4981 tggtccagtt gccattacca aaacatatcg atgaagaggc ggttttatta gccatggatc
     5041 cagaaaagga tgtggatggt ttccatcccc taaacatggg acgtctttgg tctggacatc
     5101 cagtcatgat tccctcgaca cctgcaggaa ttatggaaat gtttcatgaa tatgggattg
     5161 acttggaagg taaaaatgcg gtcgtcatcg gtcgttcaaa tatcgttgga aaacctatgg
     5221 ctcagcttct tttggctaaa aatgcgacag taaccttggc ccactcacga actcataatc
     5281 ttgccaaggt ggctgctaaa gcagatattc ttgtagtcgc aatcggccgc gccaagtttg
     5341 tgactgctga ctttgtcaaa ccaggtgcgg ttgtcattga cgttgggatg aatcgagatg
     5401 aaaatgggaa gctctgtgga gatgttgatt atgaggcagt tgcaccactt gctagccata
     5461 tcacgccagt ccctggaggt gtcggtccta tgaccattac catgctgatg gagcaaactt
     5521 atcaagcagc acttcggaca ttggatagaa aataagagaa acattcgatt aatagagtgt
     5581 attttctata gctatatcta aaatggcaga aatgaatatt aaattttaga tataagatta
     5641 caaaaggagg tctgcgtctc ctttttattg tataataaaa gtgagaggaa aaaaggatga
     5701 aagtgattaa tcaaacctta ttagaaaaag ttattattga acgttctcgt tcaagtcata
     5761 aaggagatta tggtcgtctg ctgctgcttg gtggtactta tccttatgga ggtgccatca
     5821 tcatggctgc tttagcagct gtaaaaagcg gtgcaggatt ggtgaccgtt ggaacggaca
     5881 gggaaaatat cccggctctg cacagccatt tacctgagcc tatggccttt tctcttcaag
     5941 accagcaatt gttaaaagag caattggaga aggcagaagt tgtcttgctg gggcctggtt
     6001 tacgagacga tgcttctgga gaaaatctag taaaacaggt ctttgttaat ttaagccaaa
     6061 atcagatttt gattgtagac ggaggtgcct tgaccattct tgctaggaca agtttgtcat
     6121 ttccctcaag ccagcttatc ctaactcctc accaaaaaga atgggaaaaa ttatctggaa
     6181 ttacgattga aaagcaaaag gaagatgcaa cggctagtgt tctgacttcc ttccctcaag
     6241 gaacaatttt ggtggagaaa ggcccagcta ctcgtatttg ggaagttggc caatctgatt
     6301 attaccagtt acaggttggt ggtccttatc aggcgactgg gggaatggga gatactctgg
     6361 ctgggatgat cgcaggattt gtaggccaat tccgacaagc cagtctctac gagcgtgtgg
     6421 cagtagcgac ccatcttcat tcagccatag cccaagaact atctcaagaa aattatgtgg
     6481 tcttaccgac ggaaatcagc aggtatcttc ccaaaataat gaaaattatt tgtcaacaag
     6541 agagggtaag taaagataaa cttgtttaaa atagacagat aaatctactt ccttctctta
     6601 atttatgatt cttgaaatgc gcctgcttta aggctaaact agacgtatca aagttaagat
     6661 tttgtttttg taactggaaa gagatgaaca aatcaaatac ataaaagata aactcatttt
     6721 tattcgtttg gtaaaaataa aatgcatatt tttaaagaaa gattgatgaa aaatgtagat
     6781 ttgatgtttt tacttgaata aaaagcggtt tcatagtaaa ataagaactg agaatgatgg
     6841 aggtaaatcg gtggaaaatc tgaagaaaat ggcaggtatc aaggctgctg agttcgtgag
     6901 cgatggaatg gtcgttggac ttggaacagg ctcgactgcc tattattttg tcgaagaaat
     6961 cggtcgtcgt atcaaggaag aaggattgca gattacagct gtaacaactt ctagtgtgac
     7021 cactaaacag gcagaaggcc ttaatatccc gctcaagtct attgaccaag tagactttgt
     7081 cgatgtgacg gttgatggcg cggatgaagt ggatagtcag tttaatggaa tcaaaggcgg
     7141 tggtggtgcc cttctcatgg aaaaggtggt cgcaacacca tcaaaagaat acatttgggt
     7201 ggtggatgaa agcaagctgg tcgaaaaact aggtgctttt aaattgccag tagaagtggt
     7261 tcagtatggt gcagagcagg tctttcgtca ttttgaacga gctggctaca aaccaagttt
     7321 ccgtgaaaaa gacggccaac gttttgtgac ggatatgcag aattttatca ttgacctcgc
     7381 cttggatgtc attgaaaatc caattgcttt tggacaagaa ttggaccatg tcgttggtgt
     7441 tgtggagcat ggtttattca accaaatggt ggataaggta atcgttgctg gacgagatgg
     7501 agttcagatt tcaacttcaa aaaaaggaaa atagaagggg gcataagatg tctaaattta
     7561 atcgtattca tttggtggta ctggattctg taggaatcgg tgcagcacca gatgctaata
     7621 actttgtcaa tgcaggggtt ccagatggag cttctgacac actgggacac atttcaaaaa
     7681 cagttggttt gaatgtccca aacatggcta aaataggtct tggaaatatt cctcgtgaaa
     7741 ctcctcttaa gactgtagca gctgaaagca atccaactgg atatgcaaca aaattagagg
     7801 aagtatctct tggtaaggat actatgactg gacactggga aatcatggga ctcaacatta
     7861 ctgagccttt cgatactttc tggaacggat tcccagaaga aatcctgaca aaaatcgaag
     7921 aattctcagg acgcaaggtt attcgtgaag ccaacaaacc ttattcagga acggctgtta
     7981 tcgatgattt tggaccacgt cagatggaaa ctggagagtt gattatctat acttcagctg
     8041 accctgtttt gcagattgct gcccacgaag acattattcc tttggatgaa ttgtaccgta
     8101 tctgtgaata cgctcgttcg attacccttg agcgtcctgc ccttcttggt cgcatcattg
     8161 ctcgccctta tgtaggtgaa ccaggtaact tcactcgtac ggcaaaccgt cgtgacttgg
     8221 ctgtatctcc attttcccca actgttttgg ataaattgaa tgaggctggt atcgatactt
     8281 atgctgtggg taaaatcaac gatatcttta acggtgctgg tatcaaccat gacatgggtc
     8341 acaacaagtc aaatagtcat ggaattgata cactattgaa gactatggga cttgctgagt
     8401 ttgaaaaagg attctcattc acaaacctag ttgactttga tgccctttac ggccatcgtc
     8461 gtaatgctca cggttaccgt gattgcttgc atgagtttga tgaacgctta cctgaaatta
     8521 tcgcagctat gagagagaat gaccttctct tgattactgc ggaccatgga aatgacccaa
     8581 cgtatgcagg aacggatcac actcgggaat atattccatt gttggcctat agccctgcct
     8641 ttaaaggaaa tggtctcatt ccagtaggac attttgcaga tatttcagcg actgttgccg
     8701 ataactttgg tgtggaaact gctatgattg gggaaagttt cttagataaa ttggtataag
     8761 atgacgcgct attctttgct ggtgagaggt atcaatgttg gtggtaagaa taaggtcgtc
     8821 atggcggagc ttcgtcaaga attgacaaac ttgggactgg aaaaggttga gagctacatc
     8881 aacagtggca atattttctt tacttcgata gattccaaag cccaattggt tgaaaagcta
     8941 gagactttct ttgcagtcca ttatccattt attcagagct tttctttact gagcctagag
     9001 gactttgagg cggaacttga aaatctacca gcttggtgga gcagagactt ggcacgaaaa
     9061 gattttctct tttacactga gggtttggat gtggaccaag tcatcgcgac agttgaaagt
     9121 ttagagctga aagatgaagt gctttatttt ggaaaacttg ggattttctg ggggaaattt
     9181 tctgaagaat cctattctaa gactgcctat cataagtact tgctgaaggt gcctttctac
     9241 cgccacatta ctattcgtaa tgctaaaacc tttgacaaaa ttggtcaaat gctaaaaaaa
     9301 taataaagga gacacacaat gacattttta aacaaaatcc atgaaactgc tactttcctg
     9361 aaagaaaagg gaattgcagc ccctgagttc ggtctaatcc ttggatcagg acttggagaa
     9421 ttggcagaag aaatcgaaaa tccagttgta gtagactatg ctgagattcc aaactggggc
     9481 cgttcaacag tagtcggtca tgctggtaaa ttggtatatg gtgaactggc aggtcgcaag
     9541 gtcttggctc ttcaagggcg tttccatttc tatgaaggga atcctctgga agtggtgact
     9601 ttcccagttc gtgtgatgaa agttcttgga tgtgaaggtg ttattgtaac caatgcagct
     9661 ggcggtatcg gatttggtcc tggtaccttg atggctatct cagaccatat caacatgacg
     9721 gggcaaaatc cattgatggg tgaaaacttg gatgactttg gcccacgttt cccagatatg
     9781 tctagggctt acacaccaga ataccgtgcc actgcccatg aagtggctaa aaaacttaat
     9841 atcaagcttg atgaaggtgt ctatatcgga gttactggtc cgacttatga aacaccagca
     9901 gaaattcgtt cctataagac actgggagca gatgcagttg gtatgtctac ggttcctgaa
     9961 gttatcgtgg cagcccactc tggcttgaaa gttctgggaa tttcatgtat cactaacttt
    10021 gcggccggtt tccaagaaga actcaatcac gaagaagttg tagaagtgac tgaacgtgtt
    10081 aaaggtggtt tcaaaggctt gcttaaagcg attcttgctg aattgtaaga aaaaagattt
    10141 aaaaggggga gtgcctctgt cttttcagga ttgactgcct atccgtatta aagaagaaac
    10201 agaggaatac tatgagcttc ttcctgctct tataactgaa agaagcggaa gaataggtat
    10261 gtctgatctg atagccagca ttgtgaaaga caagattcta ggatactagc attagcttcc
    10321 tagccaagca gactagtatg ataaggagag atgagaatga attgactttc tgaatttctc
    10381 agtcttatca tatatagcac aatgagattt cgcttgagtc tgcttgtaaa taaacgaaaa
    10441 gaaagataag aaataatgaa aattggtcaa cgaattatgc gctttggcat aaaaaattaa
    10501 gtatcggagt tgtatctgtt gtagtcggct ttgatttcta gctccagctg gaatttcagc
    10561 caatgaagta aagcaagatg taacatctga agtggtaata ggtgtgctag attctaagga
    10621 ggaattgaaa gagtcagaaa atgatgctcc aaaactagaa actcctctta gagaggagcc
    10681 aagactagct cctcaaacgc ttccggaagc aagtgaagtt cttgaaaaca aaagggaaga
    10741 gtcaaaagta gagataacag agccagctca agcggatgat atccgcaagg ttgttgggga
    10801 attagccaag gatataagta ttactaagtt gtatatgaca ggtcattctc ttggaggcta
    10861 cctagctcag attgcagcgg ttgaagatta ccaaaaatat cctgattttt ataaccatgt
    10921 attgaggaaa gtgacaactt tcagtgctcc taaagtgatt acttccagaa ctgtttggga
    10981 tgctaagaat ggtttctgag atgttggttt ggaaagtcgt aaattagctg ttagtggaaa
    11041 aattaagcat tatgtggttg ataatgacaa tgttgtgact cccttgattc ataataatcg
    11101 tgatattgtt acatttacag gtaattcacg ctttaaacac cgttctcgtg gctattttga
    11161 aagtccaatg aatgatattc ctaactttaa tattggtaaa caagctacct tggataaaca
    11221 tggttatcgt gatccgaaat tggataaagt gcgattcttt aagaaacagg ctctacctca
    11281 atcttctagt caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa aacaggttac
    11341 tcaaagttcg acagctttcg gaggagatgc tagaagagct gtggatggca aagtcgatgg
    11401 taactatggt cacaattctg tcactcatac aaacttccaa tctaagcctt ggtggcaagt
    11461 agatttggct aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa cagacactgc
    11521 ccaggataga ttggcaaact ttgatgtcat tcttttagac agttctggta aagaaattga
    11581 gtgaaaacgt ataatatctc ctaaagatgt gtcagcacaa attacgatta accataaaaa
    11641 acgcgctatg ttcggattga gctagaaggc tataatgccc tcagtcttgc agaagttgaa
    11701 gttttccgct ttatagctac gaatgctgaa acggcgacac aagtttctaa gccagttcaa
    11761 ccaatcagtc agactcctgt gaaagataaa acattgacaa ttcaacacag tggagcttac
    11821 attgcccgct actccataac ttgggaagaa gttccagtag ataaagatgg aaaccaagtt
    11881 gttcgtagtc attcttggga aggaaacggt tgcaaccaga ctgcaggttt tgtcctcaac
    11941 ctcccaatca aagaaaatat gagaaatctg cgagttaaga ttgagaaaaa gacgggccta
    12001 ctatggaata gatggcaaac aatctatgaa aacagaccaa ttttagctca accccaccgt
    12061 aaaattaccc attggggtac gacattgaat tccaaggtga gtgacgatga tgtcttgtaa
    12121 tctgatggta caatgacagt tagtttgtct agtttataag aaagtactac ctgagcttga
    12181 atagaactca ggtagctctc tgtgaaagaa caaaatt
//
LOCUS       DBERAE010000054        12114 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.54, whole genome shotgun sequence.
ACCESSION   DBERAE010000054 DBERAE010000000
VERSION     DBERAE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.54"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..443
                     /locus_tag="ACL70N_001910"
     CDS             <1..443
                     /locus_tag="ACL70N_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0590653.1"
                     /translation="ALKKELANYSGKKKFHAMKTQAIVTSQGRIVSLDITVNYCHDMK
                     LFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTVEDKACNHALSKER
                     SKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            593..847
                     /gene="blpM"
                     /locus_tag="ACL70N_001911"
     CDS             593..847
                     /gene="blpM"
                     /locus_tag="ACL70N_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HGS0590654.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            863..1066
                     /gene="blpN"
                     /locus_tag="ACL70N_001912"
     CDS             863..1066
                     /gene="blpN"
                     /locus_tag="ACL70N_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HGS0590655.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1310..1459
                     /gene="blpO"
                     /locus_tag="ACL70N_001913"
     CDS             1310..1459
                     /gene="blpO"
                     /locus_tag="ACL70N_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGS0590656.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1563..1682
                     /locus_tag="ACL70N_001914"
     CDS             1563..1682
                     /locus_tag="ACL70N_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS0590657.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2468..2851
                     /locus_tag="ACL70N_001915"
     CDS             2468..2851
                     /locus_tag="ACL70N_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS0590658.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2903..3592
                     /locus_tag="ACL70N_001916"
     CDS             2903..3592
                     /locus_tag="ACL70N_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0590659.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3634..3867
                     /gene="blpZ"
                     /locus_tag="ACL70N_001917"
     CDS             3634..3867
                     /gene="blpZ"
                     /locus_tag="ACL70N_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGS0590660.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFLGAGYVVGFWLLILNENQRAN"
     gene            4018..4629
                     /locus_tag="ACL70N_001918"
     CDS             4018..4629
                     /locus_tag="ACL70N_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0590661.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFVPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYKSWPLLYYL"
     gene            4790..5584
                     /gene="ccrZ"
                     /locus_tag="ACL70N_001919"
     CDS             4790..5584
                     /gene="ccrZ"
                     /locus_tag="ACL70N_001919"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGS0590662.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETVPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5581..6216
                     /gene="trmB"
                     /locus_tag="ACL70N_001920"
     CDS             5581..6216
                     /gene="trmB"
                     /locus_tag="ACL70N_001920"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGS0590663.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6342..6821
                     /gene="rimP"
                     /locus_tag="ACL70N_001921"
     CDS             6342..6821
                     /gene="rimP"
                     /locus_tag="ACL70N_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGS0590664.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6865..8001
                     /gene="nusA"
                     /locus_tag="ACL70N_001922"
     CDS             6865..8001
                     /gene="nusA"
                     /locus_tag="ACL70N_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGS0590665.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8023..8316
                     /locus_tag="ACL70N_001923"
     CDS             8023..8316
                     /locus_tag="ACL70N_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGS0590666.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8309..8608
                     /locus_tag="ACL70N_001924"
     CDS             8309..8608
                     /locus_tag="ACL70N_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGS0590667.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8625..11417
                     /gene="infB"
                     /locus_tag="ACL70N_001925"
     CDS             8625..11417
                     /gene="infB"
                     /locus_tag="ACL70N_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGS0590668.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11668..12018
                     /gene="rbfA"
                     /locus_tag="ACL70N_001926"
     CDS             11668..12018
                     /gene="rbfA"
                     /locus_tag="ACL70N_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGS0590669.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3742 a         2104 c         2742 g         3526 t
ORIGIN      
        1 tcgccctaaa aaaagaatta gcgaattatt ctggtaaaaa gaaatttcac gctatgaaga
       61 ctcaagcgat tgtcacaagt caagggagaa ttgtttcttt ggatatcact gtgaactatt
      121 gtcatgatat gaagttgttc aaaatgagtc gcagaaatat cggacaagct ggtaaaatct
      181 tggctgacag tggttatcaa gggctcatga agatatatcc tcaagcacaa acttcacgta
      241 aatccagcaa actcaaaccg ctaacagttg aagataaagc ctgtaaccat gcgctatcta
      301 aggagagaag caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa
      361 caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggtatta
      421 tcaatcatga actaggattc tagttttgca ggaagtctaa tgtaattttt gcaattcaag
      481 acgtttcgat gactattcaa gatctggatg aaaaatttta aaaaacgatg atatactaaa
      541 cttgtcaaag ttacaacaag acaaaaatta aaaataaaaa agagtatttg tcatggatac
      601 aaaaattatg gaacaatttc atgaaatgga tataactatg ttatctagta ttgaaggagg
      661 caagaataat tggcaaacta atgtcttaga aggtggtggt gctgcttttg gtggctgggg
      721 gctagggaca gctatttgtg ctgcgagtgg tgttggagca ccatttatgg gagcatgtgg
      781 atacatagga gctaaatttg gtgtggatct ttgggcagga gtaacagggg caacgggtgg
      841 attttaataa aaggagactt gtatgaatac ttattgtaat ataaatgaaa caatgctgag
      901 tgaggtttat ggaggtaatt ccggaggagc agctgtagtt gctgctttag gttgtgcagc
      961 gggtggagtg aaatatggga gacttctagg accatggggc gctgcaatag gaggaattgg
     1021 aggagcagtg gtttgtggat atttagccta taccgctaca tcataaaaat gaaagctaaa
     1081 ttttatgaag gctatattct ttattattct cttcgctttt caaacctatc ttatttatct
     1141 atccataagt atctccgata aaaaacaaaa gactattgaa ttaacatcat tgaattgttt
     1201 tgtcatatta tttctaatct atgataaatt aatttttctc tttattgcct atgttttttt
     1261 gataattttt atattaaact tgttccgtaa ctgaaaagtg atatactata tggatacaaa
     1321 aatgatgtca caatttgcag ttatggataa tgaaatgctt gcttgcgttg aaggtggaga
     1381 tattgattgg ggaagaaaaa ttagttgtgc agcaggggtt gcatatggcg caattgatgg
     1441 gtgtgcaaca acggtttgac atttctattg ggaccatttg ctataggaat aggtgtaact
     1501 ggtgctgcgg gaggagctat acttggaggt gtggcctatg cagcgacatg ttggtggtaa
     1561 ttatggattt taaaagtttt attattggtt tagtagttgg tatatttggt ccttatatgg
     1621 atgacttaat tagaaaaata ttttcaaaat cttccaaaaa ggatacggat agtactctct
     1681 aaaaaataaa tttctcccct gtatttgcta gcttaattta caggggagtt tctttaatat
     1741 tgtttcgcct gtcaaaatga tatgtgatag caggatgaaa agtctacaaa caagttggta
     1801 tcaatacaat ataaagagga aagtatgttt ttaatgctta ctttttaaat tttttaacaa
     1861 ttcaagatgt ttcgatgaca attcaagatt tggatgaaaa attttaaaaa acaatgatat
     1921 actaaacttg tcaaagttgc aacgggtgct gctacattat gttaaaaatc gctcttgatt
     1981 gataagttgg atttgttagg aaaggagtaa ataattatgg ataagaaaaa gatagtttcg
     2041 actataatat gtatagtatt tcttgtagtg tcagtagata atttttttag agacttaacc
     2101 ccgttactgt tcattttaaa tattattggc ctgtcttgct tttcagtgct aacatacatt
     2161 aacataaaag agatactctt aaatataagt aaatgatgat ttggttagtc ctagaaccaa
     2221 tcaacttatg tttatcggct tggcagattt tatgtttgtc atttgtttgt atagaggtat
     2281 ttcagaaaca gaattctatc aacaactaat cgcttatata ggtgtattct ctgcttgttt
     2341 atcacgcttc tgctcatgtg gggcttgaag tattataaaa agtagctttc tatccttttc
     2401 tgacaggata tttgagtaga aggctctatt aaattgttag tgaaataaat gaatggaggt
     2461 atttaatatg aaatacagat tattttttgt tattttcttg agtagtgtgt tggatattct
     2521 tttagggaca tttttacaaa tctctatcgt atctattggg tggcttgttc tttacagtgg
     2581 tttgtttgaa gcaggagttt tccttcttgc taataaaggg gtggcggtaa aaatcaagga
     2641 agtagatatt cgaaatcgct ttaaatttat ttttggaaaa accttatggt ttcaaattct
     2701 tttgctcatc tttttgataa tcaaacttta tcttggtttg gatgcgaggt tgattttatt
     2761 ctatggacat attttcattg tctttaatgc cttaatgtat ctattatcta gtagtcaggt
     2821 tagccttaaa aaaaacaaac tgtcttctta atcttacagc agtagagcct gacaaggtga
     2881 ggtcatagta gggaggattt ctatgaaaaa gtatcaactt ctattcaaaa taagtgcagt
     2941 cttctcttac ttatttttcg tatttggtct ttctcagctg acgcttatcg tccaaaacta
     3001 ttggcaattt tcttctcaga taggcaattt attctggatt caaaatatct tgagtttact
     3061 ttttattgga gtcatgattg tggttcttgt taagacaggc catggttatc tcttccgcat
     3121 tccaagaaaa aaatggcttt ggtattcgat tttgacagta ttagtggtag tgttacagat
     3181 ctcttttaac gttcagacag ctaaacatgt tcagtcaact gcggaaggtt gggctgtatt
     3241 gattggttat agtgggacta actttgcaga gctaggtatt tatatagccc tgttctttct
     3301 ggttccactg atggaagaat tgatttatag aggattactg caacatgctt tctttaagca
     3361 ttcgcgattt ggtcttgatt tgcttcttcc ttctatttta tttgctctcc ctcatttttc
     3421 aagcctgcct agtctgttag atatcttcgt ctttgcaaca gttggaatca tctttgctgg
     3481 tttgacccgc tataccaaga gcatttatcc atcctatgcg gtgcatgtga tcaataatat
     3541 tgtagcgacc ttcccgtttt tgctcacttt tctacatagg gtcttggggt aaaaaaacaa
     3601 aaggcttgct tttcagccat agaggaggtc atcatgtata aacacttatt tttcctagat
     3661 tccaaaactt tagatcggtt gacaccctat attctagtct tggcttctga caccattgct
     3721 tttaatgttt ttgtgctaac ctttgtatct gcggtggttt ttaatttcct aaattccatg
     3781 ctagctttaa tggctatctt cttaggagct ggctatgtgg tcggattttg gttactaata
     3841 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggctgtactt gagtacggca
     3901 aggcgacgtt gacgtggttt gaatttgatt ttcgaagagt ataaaatggt ttgttttgga
     3961 aaggctagaa ctaaaggatg acgtgtagga agtctgtttg ttgaggagga taattttatg
     4021 gagttttttg ataaatttca tgccttgtgt tttggatttt tagtactaat aattgtcatt
     4081 acagttcctt atacgattaa ccatggggat ttttttcaaa atgaatctgc attgattatt
     4141 gtaagtcttc ttgtaacctc gctgagtgtt gcttatgcta gaaagtttga aatgatttct
     4201 tttgggatgt taagcaagaa acaacttttg cttttcattg caatctttct tctaagtgtg
     4261 cttgagacgc tggtttatat tcatttcttc gctgtttctt ctggctcagg ggtccaacac
     4321 ttggcggaag tcagcagagg aatttccctg tctttgattt tgactacctc agtttttgtc
     4381 cccatccagg aggaactcat tttcagagga cttcttcaag gtgcggtttt tgacaattct
     4441 tggttagggc ttgtgctaac ttcctctctc ttttctttca tgcatggacc ttctaatgtc
     4501 ccttcgttta ttttttatct acttgggggc ttgttactgg gctttgctta taaaaagagt
     4561 caaaacctat gggtttctac tctagtacat atgctttaca aaagttggcc actcttatat
     4621 tatttataaa aattatgaaa aggtaagcag aagacggtgc ttaccttttt caagctataa
     4681 tgatacccaa gccaatccag aggcttttct ttgagaatcg ggttagagtg gttgacgaat
     4741 aggccaaaaa ctagtagaat agtaaggaaa ctttatacgg aggaaagaaa tggatttggg
     4801 tgataatgag ctaacactga ctcccatacc tgggaaaagt ggcaaggctt atatgggtag
     4861 ctatcctgat gggaagcgca tctttgtaaa aatgaacacc tctccaatcc tacctggtct
     4921 agctagagaa caaattgctc cacaattatt atggagtcgt cgtttggcag atgggcgtga
     4981 tatgtgtgct caagaatggt tgacaggcaa gatattgacc ccctatgata tgaatcgtaa
     5041 gcaaatcgtc aatattttaa cccgtcttca tcgctcacgt ccgttgatga cacaattgag
     5101 tcgtttgggc tatgccatgg aaacacctgt agatttacta cagtcttggc aggaaacggt
     5161 tccagatgct ttgcgtaaaa atcattttat cagtgaagtg atggctgatt tacgtcagac
     5221 tattccagga tttagagagg accatgcgac cattgtccat ggagatgtac gacatagtaa
     5281 ttggattgag acagatagtg gcttgattta tttagtagat tgggattcgg ttcgcttgac
     5341 cgatcgcatg tttgatgtgg cccatatgct ctgccattat atttcagaac atcagtggaa
     5401 ggaatggttg acctactacg gttacaagta caatcaaacg gtattaagta aattgtattg
     5461 gtatggtcaa ttgtcttatt tgagtcagat ttccaagtat tatatgaacc aagatttaga
     5521 aaatgtcaat cgggagattc atggtttgcg tcatttccga gacaagtatg gaaagagaag
     5581 atgagagtta gaaatcgtaa aggggcaaca gaattactag aggcaaatcc ccagtatgtg
     5641 gtcctcaatc ccttggaagc caaggcaaaa tggcgggact tgtttggcaa tgataatccc
     5701 attcatgtgg aagttggaag tggaaagggt gcctttgttt caggtatggc caagcaaaac
     5761 cctgacatca actatatcgg gattgatatt caaaagtctg ttttgagcta cgctttggac
     5821 aaggtgcttg aagctggagt gtctaacatc aagctcttgt gggtagatgg ttctgacttg
     5881 actgactact ttgaagacgg tgagattgat cgcttgtatc tgaacttttc agatccatgg
     5941 ccgaaaaaac gccatgaaaa gcgtcgtttg acctacaaga cctttttgga taccttcaaa
     6001 cgtatcttgc ctgaaaatgg agaaattcat ttcaagacgg ataaccgtgg cttgtttgag
     6061 tacagtttag tgagcttttc tcaatatggc atgaaactca atggtgtctg gctagatttg
     6121 catgccagtg attttgaagg caatgtcatg acagaatacg agcaaaaatt ctcaaacaag
     6181 gggcaagtta tctaccgagt tgaggcagaa ttttaagaga tagcctaaaa ttaggctgta
     6241 caagtgcttt tgctttacat aagttggcaa acgtgctata ctgatagtaa gaatatgaaa
     6301 agtgaggcgg ggaaatatct tcgcctcttg cttatgagga ggtggacgca atcgcaacaa
     6361 tcgtagaatt agtcagagaa gttgtagaac ctgtcataga agctcctttt gaactcgtgg
     6421 atatcgagta tggaaagatt ggcagtgaca tgattctcag tatttttgta gataaacccg
     6481 aaggaattac cttgaacgac acggcagact tgacagaaat gatcagtcct gtcctagaca
     6541 ccatcaagcc agatcccttc ccagaacaat atttcctaga aattaccagt ccaggtttgg
     6601 aacgtccttt gaaaaccaag gatgccgtcg ctggagcggt tggaaaatac atccatgtcg
     6661 ggctctacca agccatcgat aagcaaaagg tctttgaagg aactttgttg gccttcgaag
     6721 aggacgagtt gactatggaa tatatggaca agacgcgtaa gaaaaccgtc caaattccat
     6781 acagtttagt atcaaaagca cgtttagcag ttaaattata gaaaaagaaa ggatagcttt
     6841 tgaggattca aaagtgaaga aaacatgagt aaagaaatgc tagaggcctt ccgcattttg
     6901 gaagaagaca agggaatcaa aaaagaagat atcatcgacg cagtagtaga gtcgcttcgt
     6961 tccgcttatc gcagacgcta tggtcagtca gacagcgtag ctattgactt caacgaaaaa
     7021 acaggtgact ttacagttta tactgtccgt gaagttgttg atgaagtatt tgatagccgt
     7081 ttggaaatca gcttgaaaga tgctcttgcc attaattcag cttatgaact tggagacaaa
     7141 atcaagtttg aagaagcacc agctgagttt ggtcgtgtag cagcccaatc tgccaaacaa
     7201 accatcatgg aaaaaatgcg caagcaaaca cgtgccatca cttacaatac ttacaaagaa
     7261 catgagcaag aaatcatgtc tggtacagta gaacgctttg acaaccgctt tatctatgtc
     7321 aaccttggta gtatcgaagc ccaattgtca aaacaagacc aaattcctgg agaagttttt
     7381 gcttctcatg atcgtatcga agtttatgtt tacaaggttg aagacaaccc tcgtggtgtg
     7441 aacgtctttg ttagccgtag ccatccagaa atgatcaaac gtttgatgga gcaagaaatt
     7501 ccagaagttt atgatggaac tgttgaaatc atgagcgtgg ctcgtgaagc aggtgaccgt
     7561 acgaaggttg ctgttcgtag ccacaatcca aacgtggatg ctatcggtac aatcgttgga
     7621 cgtggtggtg ctaatatcaa gaagattact agcaaattcc acccagctcg ttacgatgct
     7681 aaaaatgacc gcatggtacc aatcgaagaa aatatcgatg ttatcgagtg ggtagcagat
     7741 ccagctgaat ttatctacaa tgccatcgct cctgctgagg ttgaccaagt tatctttgat
     7801 gaaaacgaca gcaaacgtgc cttggtggtt gttccagata acaagctttc tcttgccatt
     7861 ggtcgtcgtg gacaaaacgt gcgcttggcg gctcacttga ctggttaccg tatcgatatc
     7921 aagtctgcta gcgaatttga agccatggaa gacgctgctt cagtagagtt ggaagtagaa
     7981 aacgatactg tagaagaata aaagctgcta gaggagggaa agatgaaaac aagaaaaatc
     8041 cctttgcgca agtctgttgt gtctaacgaa gtgattgata agcgtgattt gctccgcatt
     8101 gtcaagaaca aggaaggaca agtctttatt gatcctacgg gcaaggccaa tggccgcggc
     8161 gcttatatca aactagacaa tgcagaagcc ctagaggcga aaaagaagaa ggtctttaac
     8221 cgcagcttta gcatggaagt ggaagaaagc ttttatgacg agttgatcgc ttatgtggat
     8281 cacaaagtga aaagaagaga gttgggactt gaataagcaa aagataagta atctcttggg
     8341 gcttgctcag cgagcagggc gcatcatatc gggtgaagaa ttggtggtca aggccattca
     8401 agacggcaag gccaagttgg tctttctagc tcatgatgct ggacccaatc tgaccaagaa
     8461 gattcaagat aaaagtcatt attatcaagt agaaattgta accgtgtttt caacactgga
     8521 attaagcata gcagtcggga aatcgagaaa ggttttggct gtaacagatg ctggatttac
     8581 aaagaaaatg aggtctctta tggaatagaa gaggaggaca tgatttgtct aagaaaagat
     8641 tgtacgaaat cgcaaaagaa cttggaaaag aaagtaaaga agttgtagcg cgtgcaaaag
     8701 agttaggctt ggatgtgaaa agccactcat caagtgtgga agaagctgtc gctgcaaaaa
     8761 ttgctgccag ctttaagcct gcagctgctc cgaaagtaga agcaaaacct gcagcaccaa
     8821 aagtaagtgc agaaaagaaa gccgaaaaat ctgagccagc taaaccagct gtagctaagg
     8881 aagaggcaaa accggctgag ccagttgctc cgaaaacaga aaaagtagca gtgaaaccgc
     8941 aaagtcgtaa tttcaaggct gagcgtgaag cccgtgctaa agagcaggca gaacgacgca
     9001 agcaaaataa gggcaataac cgtgaccaac aacaaaacgg aaaccgtcag aaaaacgacg
     9061 gccgtaatgg tggaaaacaa ggtcaaagca accgcgacaa tcgtcgcttt aatgaccaag
     9121 ctaagaagca gcaaggtcag caaaaacgta gaaatgagcg ccgtcagcaa gaggataaac
     9181 gttcaaatca agcggctcca cgtattgact ttaaagcccg tgcagcagcc ctaaaagcag
     9241 agcaaaatgc agagtacgct cgttcaagtg aggaacgctt caagcagtat caggctgcta
     9301 aagaagcctt ggctcaagct aacaaacgca aggaaccaga ggaaatcttt gaagaagcgg
     9361 ctaagttagc tgaacaagca cagcaagttc aagcagtggt tgaagtcgtc cctgagaaaa
     9421 aagaacctgc agtggataca cgtcgtaaaa aacaagctcg accagacaaa aatcgtgacg
     9481 attatgatca tgaagaagat ggtcctagaa aacaacaaaa gaatcgaagt agtcaaaatc
     9541 aagtgagaaa tcaaaagaat agtaactgga ataacaacaa aaagaacaaa aaaggcaata
     9601 acaagaacaa ccgtaatcag actccaaaac ctgttacgga gcgtaaattc catgaattgc
     9661 caacagaatt tgaatataca gatggtatga ccgttgcgga aatcgcaaaa cgtatcaaac
     9721 gtgaaccagc tgaaatcgtt aagaaacttt tcatgatggg tgtcatggcc acacaaaacc
     9781 aatccttgga tggggaaaca attgaactcc tcatggtgga ttacggtatc gaagccaaac
     9841 aaaaggttga agtggataat gctgacatcg aacgtttctt tgtcgaagat ggttatctca
     9901 atgaagatga attggttgag cgtccaccag ttgttactat catgggacac gttgaccacg
     9961 gtaaaacaac ccttttggat actcttcgta actcacgtgt tgcgacaggt gaagcaggtg
    10021 gtattactca gcatatcggt gcctaccaaa tcgtggaaaa tggtaagaag attaccttcc
    10081 ttgatacacc aggacacgcg gcctttacat caatgcgtgc gcgtggtgct tctgttaccg
    10141 atattacgat cttggtcgta gcggcagatg acggggttat gcctcagact attgaagcca
    10201 tcaaccactc aaaagcagct aacgttccaa tcatcgtagc tattaacaag attgataaac
    10261 caggtgctaa cccagaacgc gttatcggtg aattggcaga gcatggtgtg atgtcaaccg
    10321 cttggggtgg agattctgaa tttgttgaaa tctcggctaa attcaaccaa aatatcgaag
    10381 aattgttgga aacagtcctt cttgtggctg aaatccaaga actcaaagca gacccaacag
    10441 ttcgtgcgat cggtacggtt atcgaagcgc gcttggataa aggaaaaggt gcggtcgcaa
    10501 cccttcttgt acaacaaggt accttgaatg ttcaagaccc aatcgttgtc ggaaatacct
    10561 tcggtcgtgt ccgtgctatg accaacgacc ttggtcgtcg tgttaaagtt gctggaccat
    10621 caacaccagt ctctatcaca ggtttgaacg aagcaccgat ggcgggtgac cactttgccg
    10681 tttacgagga tgaaaaatct gcgcgtgcag caggtgaaga gcgtgccaaa cgtgccctca
    10741 tgaaacaacg tcaagctacc caacgtgtta gccttgaaaa cctctttgat acccttaaag
    10801 ctggggaact caaatctgtt aatgttatca tcaaggccga tgtacaaggt tctgttgaag
    10861 ccctttctgc ctcacttcaa aagattgacg tggaaggtgt caaagtgact atcgtccact
    10921 cagcggtcgg tgctatcaac gaatcagatg tgacccttgc cgaagcttca aatgccttta
    10981 tcgttggttt caacgtacgc cctacaccac aagctcgtca acaagcagaa gctgacgatg
    11041 tggaaatccg tcttcacagc attatctaca aggttatcga agagatggaa gaagctatga
    11101 aagggatgct tgatccagaa tttgaagaaa aagttattgg tgaagcggtt atccgtgaaa
    11161 ccttcaaggt gtctaaagtg ggaactatcg gtggatttat ggttatcaac ggtaaggttg
    11221 cccgtgactc taaagtccgt gttatccgtg atggtgtcgt tatctatgat ggtgaactcg
    11281 caagcttgaa acactataaa gacgacgtta aggaagttac aaacggccgt gaaggtggat
    11341 tgatgatcga cggctacaat gatattaaga tggatgatgt gattgaggcg tatgtcatgg
    11401 aagaaatcaa gagataagat tttttgctcc tttcttaggt ggtgagggac gcaagcaaac
    11461 cgatggtttc attgcttatt tttgagccta gggtctcaaa aataccctgt gatgggactg
    11521 ataaatcagt tccatcactt tcaccacggc gaaagaagca gatgacttca aattgaactt
    11581 cgtttcaatt taaactgaaa atcaagaagt ttaaaatagc taggtctgct ggcctagctt
    11641 ttggttcaaa gtagagaaag gaatatcatg gcaaatcatt tccgtacaga tcgtgtgggc
    11701 atggaaatca agcgtgaagt caatgagatt ttgcaaaaga aagtccgtga tccacgtgtc
    11761 caaggtgtga ccatcacaga tgttcagatg ctgggtgact tgtctgttgc caaggtttat
    11821 tacaccattt tgagtaacct tgcttcggat aaccaaaaag cccaaatcgg gcttgaaaaa
    11881 gcaactggta ccatcaaacg tgaacttggt cgcaatttga aattgtacaa aatcccagat
    11941 ttgaccttcg tcaaagacga gtccatcgag tatggaaaca agattgacga gatgctacgc
    12001 aatctggata agaactaaag aagaggggtt gcccctcttt tttggtggag gaaaataggt
    12061 tgaatttgaa atggaaaaat attcttttat aatagattga aactagaata gtac
//
LOCUS       DBERAE010000055        10735 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.55, whole genome shotgun sequence.
ACCESSION   DBERAE010000055 DBERAE010000000
VERSION     DBERAE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.55"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(87..1511)
                     /locus_tag="ACL70N_001927"
     CDS             complement(87..1511)
                     /locus_tag="ACL70N_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS0590670.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVTWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2056..4335)
                     /gene="pulA"
                     /locus_tag="ACL70N_001928"
     CDS             complement(2056..4335)
                     /gene="pulA"
                     /locus_tag="ACL70N_001928"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGS0590671.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4447..6405)
                     /gene="ligA"
                     /locus_tag="ACL70N_001929"
     CDS             complement(4447..6405)
                     /gene="ligA"
                     /locus_tag="ACL70N_001929"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGS0590672.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6498..7676)
                     /locus_tag="ACL70N_001930"
     CDS             complement(6498..7676)
                     /locus_tag="ACL70N_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0590673.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7756..8619)
                     /locus_tag="ACL70N_001931"
     CDS             complement(7756..8619)
                     /locus_tag="ACL70N_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0590674.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISSHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8622..10523)
                     /locus_tag="ACL70N_001932"
     CDS             complement(8622..10523)
                     /locus_tag="ACL70N_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0590675.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3215 a         2371 c         1911 g         3238 t
ORIGIN      
        1 accaaaaagt tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca
       61 ggaaaacaat ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt
      121 gtcatcgctt caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca
      181 aggaatggga aattatctgg accacgctgg gttttattat taatgtggac tgtacctact
      241 tcaagttttt cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga
      301 aggccgaatt cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg
      361 attggtaaaa caggaccaaa tggctcttcc catgtcactt tcatatcttt tgtaacttgg
      421 tcaaaaagca ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc
      481 tctttttctt gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata
      541 acaggtgtaa tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc
      601 tgaagcaaag tagctaattt atctgctaca ctttcgagaa caatgacacg tttaatggcc
      661 gtgcaacgtt gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc
      721 aaatctgcat cttctagtac aagagctgca tctttcccac caagttccaa catgatagga
      781 cgcataccag ctaaacgacc aatacgttct ccaataggag ttgaacctgt aaagttgatg
      841 aagttgactt ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg
      901 gtgttgaaaa cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca
      961 gaaatggaac cttgtgttgg tggcttcaac atgaccacat tccctgcaat caaggcaggt
     1021 gcaattttag aagcagataa attaactgga taattaaagg gagcaatcgc tagcacgata
     1081 ccaactggtt cacgacggac aacagccagt ttgtttttac ttgctgcctc aaaaccacca
     1141 ccttccattg cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct
     1201 gctgtacgca ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg
     1261 atagtaccaa ttttttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc
     1321 gcacgttcaa ttgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata
     1381 gcctcatcag cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt
     1441 ggtgaataaa tcgtaatttc ttgttcagat gatttccatt ttccatttac taaattctga
     1501 tatcttgtca aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag
     1561 aaaatcacaa ccctttttgc aaaatttttg agattatttt cacaatcttg atttttcaaa
     1621 gtatactcaa taaaaattaa aaaaatccac tacgtcaagg cgaggctaat gtggtttgaa
     1681 gaaattttcg aagagcatga atgagtatca tctatagtaa aataaaaaaa ctgaacaatt
     1741 tggttgggga cagccaaacc aatttctcac aatgtttcag aaacaagggt gtgctattcc
     1801 aatttcagcc tactataact gtcatagatt gctgaaacaa agtctaggta aaagtcttca
     1861 taataaaaag acctcctatc aagtgttcaa aaactttgat aggaggtctt gttttgtgaa
     1921 aatatttatc aaattttcta tacaagtgag ctgttagcca ggttctttct attctttcaa
     1981 tttcaatgaa tggatttttt actaatactc ataactggga atttgtctgt gtaaaaatag
     2041 cgagatagat ggtatttata aaacactcaa gacagctaga ctaatatcat ttaaaacatt
     2101 atcttctttt gagcgactgt tggttaccaa catagctaaa tttcctgcat tttcaaattg
     2161 atagggttct gatttagcat tcacaactac caagaggtgt tctttgccgt gaacttcata
     2221 gataaggcag ccgctatgtt caatcgcaga atgcacaaag acatgatggt aaatttcatc
     2281 atagctagag taagaaaagg caccagtttt tgtcttcaat cggatgactt gacggataaa
     2341 ctcaatactg tcttgacgct cattaatcaa gttccagttc acttggttca cactgtcagg
     2401 agcattatag ctattcatcg cacgctctct atcatcatgg gtcaactcac cattttcacc
     2461 agtcgcaacc agtttggtac gaccaaattc ttgaccgatt tccataaagg ccatcccctg
     2521 catgagcaga ttcatggctg tggcagtttc gaccttgcgc atgatttgct ctgaactttg
     2581 gtctggatga agggttgcca ataaatcgtg aagattgtaa ttgtcatggg cttctacata
     2641 gttaagcacc tgatttggat gtgtatagct tcctaattca cgacttccta ggattgcttt
     2701 agctagaatt ggctctgtcg cagcaccact gacaaaacct gacttgatag caccataaac
     2761 ttctccccct ttgacagcat cgcgctgatt gtcattaaag aaaccaatat ttggcatctg
     2821 gtaggcattg tccttcttgg ccttatcata aggggcaaga cctgttccca tatcccatcc
     2881 ttctccatag aggataatgt tggagtcgat ttcatccaag ctttgacgaa tcatctgcat
     2941 ggtcttgaca tcatgaatcc ccatcaagtc aaaacggaag ccgtcaatat tatattcctg
     3001 cacccagtat agaagagaat caatcatata cttgcgaaac atttcgtgtt cactggctgt
     3061 ttcatttcca acacccgttc cattctggaa ggtaccatct ggattcatac gataatagta
     3121 atcagggact gttgtttgga atggtgcatc aacaactgag aaggtatggt tatagactac
     3181 atccataatg actccaatac ccgcatcgtg ataagcttga accatcacct tcaaatcacg
     3241 aatgacctga gctggatcat ctggattagt tgaaaaacta gtttctggcg cgttatagtt
     3301 ttgtggatca taaccccagt tgtaggttac atttccatcc tcatcgtatt ctttatgacg
     3361 gtctgcaatt ggttgcaatt gaacataatt gtagcccagc ttcttgatgt aatcaaaagc
     3421 agttgactgg ccgtattggt taactgttcc agcctgagca gcacccaaga aagttcctcg
     3481 aagatgttca tctacacccg atgtaggtga tttagtcaaa tcacgaatgt gcatttcaca
     3541 gataactgcc ttacatggat tttccaagcg ccaagtagcc tccgaaccgt gcttaacctc
     3601 gaagttttca acttgctttt ctacatggct cagaatagct gaacgtttgc catcagggct
     3661 ggtcgcgatt gtataaggat cacgtgtcag tgtttggtga tgagggaatt ggacttgata
     3721 ctgataagtc ttacctacca aatcttcttc aacatccaaa ctccagacac cgattgtatt
     3781 gtccttatga ttataagagt agctattgcc tcttttcatc tcaaaagtct tccaaacggg
     3841 tgcatcatta gcagctgatt cataaacgac aacttgcact tctgtcgctg taggtgacca
     3901 gagagaaaaa tgagcctgat tgtcctctac acggcaaccc aattctcctt ggtaacccca
     3961 atgatgatca aaactagcac tgttaatggc cttatcaaag gcaaaaggat tttgattttt
     4021 atagaaagga ctggcaatag caggattttc agagtaataa atcctatcat cgccttccaa
     4081 aatccagacc tctgttaata ggggatagtg attaaaacgg atagaatatt ctttactagt
     4141 ttgacctgta tgaaccacaa aattcaagct ttctataaca tgtgaacttg ggtgttcaaa
     4201 gctaaataaa gctccaaaat aatcttcttt gtaggttagc aaatcaattc gttgatcctg
     4261 actttttaca aaggagcaag tgtcatattc tccattctta cgatggtaat gaatgcgcat
     4321 agggtagtta tacatttttt atttttcctt tttactttgt ttctatttca ctaataaatt
     4381 tttgtcaatc tcgtctcaat taacagacat agtcatattc tctaaactct gtttttaaac
     4441 gatccattac aaactttcta gccatgcctc atctctgacc tggataccaa gttcttgtgc
     4501 tttttgcagt ttacttccag cgtctgcacc taccacgacg aggtcggtct ttttagaaat
     4561 actacctgtc actttggcac ccagactttc gagtttactt ttagcttctg agcgcttgag
     4621 tcgttccaat tttcctgtca ataccacggt caaacctgac aaggccgcat ccgctactac
     4681 cgtctgtcct ttatagtcca gattgacccc agtttctttc aattctctga gcagaatttc
     4741 agagccttct gtcgcaaaat aagtctgaag acttttggca atcacgccac ctagactttc
     4801 aatactagcc acttcctctg aatctgcctg agacagattt tcaattgaat ggaaatattg
     4861 aagtaaaagc tgactaacct tgcttccgac atgacgaatt cccaaaccaa ataagagctt
     4921 ctcggcagag ttttcctttg atgcttggat agcctgatac agtttagcag cggacttttc
     4981 cttaaccccc tctaaaagga ggaaatcctc ttcttgcaaa cgataaatat ccgccacatc
     5041 cttgactaaa ttagcagcaa aaagcttctc aacaatagat ggaccaaggc ctgtaatatt
     5101 catagcatca cgagaagcaa agtgaatcaa gccttccatg atttgagcag ggcaacgcgg
     5161 attgatacaa cgtagggcca cttcatcttc aaagtgcaac aagtcagagt tacaacttgg
     5221 acagtttgta gggatatcta gtttttcttc agaaacccgt ttggactcta ccacacgtaa
     5281 aacggcaggg atgatgtcac cagccttata tacaatgacc gtatcgtctt ttcggatatc
     5341 tttttcagca atataatcta cattgtgcag ggtcgcacgg ctaacagtcg taccggcaag
     5401 ttgtactggt gttagattag cagttggagt tacaacaccg gtacggccaa ctgtccagtc
     5461 aactgataag agttgagctt ctttttcttc ggcagggaac ttgtaggcta ctgcccactt
     5521 tggagcctta acggtaaaac caagttcttc ttgacttgct aggtcgttga ccttgattac
     5581 cactccatca atatcgtaag gcagattttc ccgttcctgt cctacttctt ggataaaatt
     5641 ccagatttca tctatgtttt cagccaagat tcgcttagga ttgaccacaa aacctagttg
     5701 ttctaggtac ttcaaaccct tttcttggct atcacgagtt gaagggctgg cttcttgata
     5761 gagaaacgtt gcaagattac gcttggcaac tactgctgta tccaactgac gcagagttcc
     5821 tgctgccgca ttacgaggat tagcaaattc aggctctcca ttttcttggc gcacttggtt
     5881 aacttggtca aaggaagcgc gtggcatgta acattcccca cgaactgtga tatctagttc
     5941 ttctggcaaa gtcaaaggga tgtccttaac acgcttgagg ttttctgtga tattttcacc
     6001 aattgaacca tctccacgtg ttaccccagc aaccaaaatc cccttttcat aagtcagcga
     6061 gatagataag ccatcgattt tcagctcaca aatataggtc ggatgagcca cttccttacg
     6121 aacacgcgca tcaaaagcat ctagctcctc acgtgaaaaa gcatcctgca aactataaag
     6181 aggatactga tgactgtatt tttcaaaacc atctaaaacc ttgccaccaa cacgatgagt
     6241 cggactgtct gctagcactt gctctggata agcagtttct aactcgacca actcacggta
     6301 aaggcggtca tactcactgt ctgaaaccga gggattatcg ctggtatagt actcagtcgc
     6361 atagcgattg agcaaagcga ctaactcatt cattctttta ttcataagac cattttacca
     6421 taaaacaagc cctcctcaca aacgagaagg gcggaaaaaa cacttagttt gaaattattt
     6481 ttgaaactca agcaacctta tatcaatttt tcaaaatgag ttcgaacata aataaacgat
     6541 atacaagaca agatgataac accacttcca attatcagga aagaagagag atgtacactt
     6601 ggcaagactg tcataaatcc ttttgcaata ggcataaata gaatagctaa ggtaaaaatt
     6661 gtactcagta ctcttccaag aaattcgctc tcaaccttgg tttgtacttg agtaaaaaag
     6721 tgaatattaa aaatcgtcat aaacaattca caaactaaat ttccagaaaa ggaaagaaaa
     6781 gttggaagtg gtaatcccat cataaaaact ccgacacctg tcaaagccag taaaatcaaa
     6841 agattataaa tattagcttt aattttacta gctagaagag ccccaatgat ggaaccaata
     6901 gcccccatag ttaaaatact tgcataggct ccttctgacc cgtaaagctg attcgaaaag
     6961 ggaagtagaa attcaaaagc tgcaaaaaag aaattaacgc tggaagctac cagcaaaagg
     7021 aagaaaattt cttgctgatg ccagatatag tgtaacccat ccttgatatc tacaaaaata
     7081 tctctcccag taaaagcctt tttctcttga acttttgctt cctcttttgg aaggaaagcc
     7141 actagaacaa aagcaatgaa aaaagtcagc gagtctagca gtagcgtcat atggagactt
     7201 gcaaactgta aaacaaggaa ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc
     7261 agctctaggc gagaattata gatcacaatc tcatctttct ccaccacttc agttatgata
     7321 gctttattgg ctgtgcgaga aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc
     7381 aaagcgccaa tcatccagct atcattcctt atgaaagaaa tagccagaca aagaatccca
     7441 caaacaagat ctgccgtcat taaaatctta cgacgagaaa aacggtctga aataactccg
     7501 ccaaagggat tgacgagaat agatgtgacg agctcagaaa tctgatacat tcctaaaact
     7561 gtctgtccta tagtccccat agaagccaac cagacactat ttccataatc atagagcata
     7621 tttcccattt tattgatagc cccacggcta atcaactgca ctgcatagcg attcatatta
     7681 aagctcctct caaattttga aactattgta tcaaaaccga aaggagcttt ttattttttc
     7741 ccttatttgg gaaaattaac ttttgacaaa tttttcgtag tgttcctgat aataggctac
     7801 ttgctctgga agacctaaca catcaaaaat atgtatggcc tcttgcatct gcttacagcc
     7861 ttctttacac tgtccttttt gatataaggc aaaacctttt aaataatgga aaacattacg
     7921 ctcataaagc ttaatacctt tgtcaataat cttctctgta taagcctcaa aatagttggc
     7981 attataaaaa gaagaatgct ctaaacaatg ctggtaacaa ttgagggcca aaatcaacac
     8041 taatctctta tggctactaa tctcttggta aaattcctcc ctctccataa cttctctacc
     8101 aatccgagtg acataatcca catcgtagaa actatagagg ttaccgaaaa gaatcaactc
     8161 atacatggtc cattcttctg ttttgaagag ataatctgct accttatcca aatcatcctg
     8221 cttcatatca taactcgcat ctctttgaca aatcagaccc tgtagcaaaa tccagttcag
     8281 ctcaaaataa aggggagtcg tcgaactctt agacttttca agttgttctc tttgaagctt
     8341 ttgaaaacct gcaatatcgt ttgaatagta aagtgggata atctgtgcca tcatagacac
     8401 atgttcatga ttatgaaaat tccttgcctt atccatgaaa ttttcgattg ttacatgaat
     8461 gttatccaaa atctcaaaga aacgggagac tgccaggtca gactccccaa gctcaaagcg
     8521 agataactga gaggtagagc aggattcgcc tgctgcttcc ttcaaagaat aatttccact
     8581 tgttcgaaat tcacgaaata cttttccaag atgttccatc tttacacctg ctctgataat
     8641 tcttcccact caagcatagc ttcttcctga cgatggctga ttttgtccag ctcagcctgt
     8701 aattccatga gtttgtcggc atcgtttgtt tccaacattt gttcagaaat ggcttggctt
     8761 tgactttcta gctcttcaat ttcagcttct agactttcga tttgtcgcat gagtttgcga
     8821 acttcttttt gactttcttt ctgggcctga tagtcattga ctggacttgc ttcctttgct
     8881 tgattgctag ttgaagcttc ctcagtctga ctcatttctg ctgttgcttt cttctcaaca
     8941 tagtagtcgt aatctccaag gtagagagtt gaaccattct cagacaattc caaaacatga
     9001 gttgccacac gattgataaa gtaacgatca tgactgacaa aaagcaaggt accatcaaag
     9061 tcaatcaagg cattttctag cacttcctta ctatcaatat ccaagtgatt ggtcggctca
     9121 tccagaatca aaaagttatt gttttccata gacaatttag ctaaaagcaa acgagctttt
     9181 tcgccaccag atagcatgcc gactgatttt ttaacatcat ctcctgagaa aaggaaggct
     9241 ccaagacggt tgcggatttc aacttctggt gtcaatttga aatcattcca gagttcatcc
     9301 agcaccgtat tacttggtgt cagcttgctt tgggtttggt catagtaacc aacctcaaca
     9361 ttagcgccaa agcgcttttc tcccttgata aacggaattt gatccacgat tgatttgata
     9421 aaggttgatt ttccgatacc attgggacca acgatagcaa cagcattcat cttacgaagg
     9481 tctaggttaa tcggttgtga caggacttcc ccatcatagc caacagccgc attttcaaca
     9541 gtcaaaacaa cattgcccga cgttttttca gactggaagg tcatgttggc tgctttcttg
     9601 ccagcttccg gcttgtccaa acgctccatt ttttctagtt gtttacggcg agattgagca
     9661 cgtttagtcg ttgaagcacg aactagattg cgattgacaa agtcttccag agcagcgatt
     9721 tccttctgtt gcttttcata gttttttgcc tcagtagcta gcttttgctc cttcaactcg
     9781 acaaaacgag agtaattccc cacatagcga tccaaggaat gcttggtcaa atctagcgta
     9841 attgtcgcaa ccttgtccaa gaaataacgg tcgtggctga cgataatgag ggcaccgcta
     9901 tagtttacca agtaattctc tagccaggag atggtttcaa tatccaagtg gttagttggc
     9961 tcgtccaaga ccaagagatt gggcttttca aggagcattt tagctagagc caaacgagta
    10021 ttttgaccac ctgaaagttc agctattttc atctgccaca tagactcgtc aaacttgaat
    10081 ccattcaaaa tcgctcgaat atcagcttca taggtaaagc cacctgcttg gcgaaaattc
    10141 tcagataagc ggtcataatc tgacatcagt ttatccaaat cctcaccaga cttttcaccc
    10201 atctccagct ccatctgacg cagttgtctc tccgtccgac gcaaatcatt aaagacatga
    10261 agcatttcat cgtagatggt attttcagac tcaaaacggc tatcttgggc taggtaagac
    10321 agagaaatat cttttttctt attgatttct ccgctagttg gctcctcttc tccaactaaa
    10381 atcttcaaaa gagtagactt acctgcacca tttttcccaa caagagcaat ccgatctcgt
    10441 tcatcaacct gcaggttgat attatcgaaa agaacctctc ctgcaaaaga acgttcaatt
    10501 ttattagctt gtaaaataat cataagagta gtatagcatg tttccctaag gcattcaaga
    10561 taatcgtaag tcttttagta caacttttat aacataaaat aaactaaatt atgtatattt
    10621 tatattagat tccttcacta tcttgttgga ttttctaacc agctaatctt gtttcaaata
    10681 gttatcgcac aagcctatta tttaattctt ttcattattt acgtacgcgt atagc
//
LOCUS       DBERAE010000056        10344 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.56, whole genome shotgun sequence.
ACCESSION   DBERAE010000056 DBERAE010000000
VERSION     DBERAE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.56"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..141)
                     /locus_tag="ACL70N_001933"
     CDS             complement(<1..141)
                     /locus_tag="ACL70N_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS0590676.1"
                     /translation="MAYSIDFRKKVLSYCERIGSITEASHVFQISRNTIYGWLKLKEK
                     TGE"
     gene            complement(355..2118)
                     /locus_tag="ACL70N_001934"
     CDS             complement(355..2118)
                     /locus_tag="ACL70N_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGS0590677.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(2127..2717)
                     /locus_tag="ACL70N_001935"
     CDS             complement(2127..2717)
                     /locus_tag="ACL70N_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGS0590678.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2815..3306)
                     /gene="rocS"
                     /locus_tag="ACL70N_001936"
     CDS             complement(2815..3306)
                     /gene="rocS"
                     /locus_tag="ACL70N_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGS0590679.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3383..4075)
                     /locus_tag="ACL70N_001937"
     CDS             complement(3383..4075)
                     /locus_tag="ACL70N_001937"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGS0590680.1"
                     /translation="MKIGIIAAMPEELAHLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(4092..4406)
                     /gene="macP"
                     /locus_tag="ACL70N_001938"
     CDS             complement(4092..4406)
                     /gene="macP"
                     /locus_tag="ACL70N_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGS0590681.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4418..4963)
                     /locus_tag="ACL70N_001939"
     CDS             complement(4418..4963)
                     /locus_tag="ACL70N_001939"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0590682.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4973..6352)
                     /gene="glmU"
                     /locus_tag="ACL70N_001940"
     CDS             complement(4973..6352)
                     /gene="glmU"
                     /locus_tag="ACL70N_001940"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGS0590683.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRCRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPRNQ"
     gene            6486..7286
                     /locus_tag="ACL70N_001941"
     CDS             6486..7286
                     /locus_tag="ACL70N_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGS0590684.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSIWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7381..8223
                     /locus_tag="ACL70N_001942"
     CDS             7381..8223
                     /locus_tag="ACL70N_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGS0590685.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYSLNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNTGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8223..8705
                     /locus_tag="ACL70N_001943"
     CDS             8223..8705
                     /locus_tag="ACL70N_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGS0590686.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8705..9325
                     /locus_tag="ACL70N_001944"
     CDS             8705..9325
                     /locus_tag="ACL70N_001944"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0590687.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPADRILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9578..9673)
                     /locus_tag="ACL70N_001945"
                     /pseudo
     CDS             complement(9578..9673)
                     /locus_tag="ACL70N_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            10086..10344
                     /locus_tag="ACL70N_001946"
                     /pseudo
     CDS             10086..10344
                     /locus_tag="ACL70N_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
BASE COUNT         3177 a         2177 c         1797 g         3193 t
ORIGIN      
        1 ctctcctgtt ttctctttta gctttaacca gccataaatg gtattacgtg agatttggaa
       61 aacgtgtgat gcttctgtta tactacctat tcgctcacaa taagagagaa cttttttacg
      121 aaaatctatt gaatatgcca taagaagatt ataccacatt gtgtactatt tttggttcat
      181 tttactatat tttataagtt atagtgtagc attccaactt caaagcacta taaagtaaat
      241 tgaaacaaga acaatacaaa caattctcgt aaacggattg caaccacaaa aaagcaagca
      301 ttcacaagaa tacttaccta tcatgggagg aacaaccgtt cctctttttt attactaaaa
      361 ttcaaagaat tccaatgctt ttttcaagag caaatccgta tattctggat cttcttgggc
      421 tacttctatt tcccgctgaa ctttttccaa atcatctgta atcactccat ctactcctaa
      481 gtgaagagat ttgctgatag cttctgaatc attgacagtc cagacataaa gtttctgatc
      541 cgttgtccat agtttgctta caaaatattc atccaaggtt gagtactcca tagtatatcc
      601 tgtcgctctt gttttaggaa agacagaatt gtagggcatg atgaaataaa ctggcagttc
      661 ggcatcatac tgtcttactt tttcgacaac atggtagtct aaagactgga tttgatgtcc
      721 ataaatcttg agctttgcag cataacgggc taaaaagcgg ttcatcatgt ctggactatc
      781 ttttttactg gttttaattt caattagtaa tttttgacca agttcgttgg ctcgactgag
      841 ataatcttca aagcttgaaa ttttagtctg gtagccattt tcaaaaatat caatcccttt
      901 aagctcctcc aagtttaagt cttgaggact tttattgata cctgctagat ttttcaagtt
      961 agcatcatgc atcatgacaa actgcccatc ttttgtttcc tgcacgtccg tctccaccaa
     1021 gtctggtttg agttgtgctg tagtttccaa ggactctact gtattttgaa tcccatttgc
     1081 attggaaacc cctcggtgag aaataagttg aggtagatga accatgggag cctccagata
     1141 aatataacct tctaaggcaa agaaaagact ggcacaagtc atgacacccc atcgcacgat
     1201 gtgatctttt tctctcctag gaagcatatc cagctccttt cctgtcaaaa atgaaacaaa
     1261 tttaaccaaa aaataagtca gagccatata atagagattt ttaatcacga caaaattcaa
     1321 aataccaaga atcagagact ctctctgagt gatatcatct accaaagttt gagccaataa
     1381 taaagggatc aaaggaagat aaaataataa atgtgctttg agcaagatgt aaaataaatt
     1441 ccaagcataa aaagtaactc tcttcttggt tttctccaag ctaaacatca ctgcttctcg
     1501 aacagtcagc tgatcatata caatcttcgg aagggcaaac atcaatctga cagagacata
     1561 gagaaagata agagatagaa gtaggatgct cagccaccac atccaatatc tatcttctaa
     1621 ataagcttgg ataaactctg gaatgacgat tttattaaga taataaatct tcagcatttt
     1681 ccgtataaaa ggaaacagca tagctatata gaaaaagata aacaaggctt tagcgcaagt
     1741 tagctttttc ataaatccaa aactttcatg gaaaaccttg cggatatact caattagcct
     1801 tcgcttttca ttatagagga gatgacgagc accaataaag aggagtccta tttgaaaata
     1861 agcaaccaga aggttaatta caatcaaggc taaaaaagct agactaatca atggagaatg
     1921 agtaaggatg gctaagacat tgttatagga aataaaaaga taacctgtct gatctaataa
     1981 gaagctagcc aaccatgaat tgaatggtac ccacaaatac tccactatca taaaaatcaa
     2041 gaaaaataga aagaggattt tatcaagatt gaggtaaatc tgtttaagac ccaatttttt
     2101 aggtttttca ggtttcatag gcactcctag tcaaataatt gagacaagtc caagccacca
     2161 aaaggattgt ttgataagct actttctgtc tctaacaatt ccctagcttg atccgactct
     2221 aagaaggatt cgtaaacacg cgccgtcatc cgagcatcct ctaaactatt atgagactga
     2281 ccttgaaatc caagaaatga ggcaacagtt tgcaatttga gattggcaat accatgtaaa
     2341 tctgaactcc gacgttcaaa agcttcatca tacaaatcca ccttgtactg ttggctatag
     2401 tctaaaccat gctctgctaa aataggtaaa tcacttttag cagcattgta gcctatcatc
     2461 agcaaagaac ccacaaactc ttggaattct tctaagactt tctcaactgg aggagcatct
     2521 tttaaggtct cagctgtaat cccggtcaaa ccattgataa agctttttag agggacgctg
     2581 gtatgaacat aggaatcata ggcatcgatt tcccgaccat ctctaaaacg cactgccgat
     2641 acttgaatca agtgtgtttg tccttcgtgc tgattaaatt ctaagtcaaa agcaatgtaa
     2701 tcttctaatc gttccattct gtacctctcc tctactgtct ctgttctaat caactatact
     2761 attcacaaac aaaagaagcc atcaggttag catttaacct aaacagctcc ttgattatcc
     2821 tccaaataaa cgagcaaaaa agcctttttt agtggattgg acttcttctt ttgcttggtc
     2881 cagctctagc ttaagatttt cttgatcctt catggcttga agggtcaatt gttgttgctg
     2941 atctaattgt ttgtctttct cagcaatctg acggtctttg atacgcatct gctcgtcttt
     3001 ttctgataac tgacgatcct tggcttttaa ttgttcataa agacgaagaa tttctgcatt
     3061 cttctcatcc actagaatct ccatcagttc acgttgtttg acatcttcac tgacaggttc
     3121 atcttcaaaa atcgtttttt tatagatttc ttctagctta atcaagccac ttctggtaac
     3181 aactgttacc cctttgtcat ttttatctgt gtcttcttct ggtaattctt tgacacggtt
     3241 attgattgct tggcgagata atcctaagac ctctgcaatc tcactgacgg tcatttcaat
     3301 actcataata tcctctgaaa cgttttctag cttttcttta cttaaatctt atcataagct
     3361 agaaaaactg tcaaatttcc gcttaatcta aagccttcaa aaaggccaac aagacttggg
     3421 cagagcgacg tccagcttcg ataataaact catcaaaaaa gatgtttgct tcatggttgg
     3481 cattgtcact catagctctg atgactaaga ctgggagatt gagggcatgc gctgcttgag
     3541 caatagctgc cccctccatc tccacggcta aaacttctgg gaaatgggac ttaatcgctt
     3601 ctatcttgtc atttcctgca acaaaactat ctcctgtagc aatcaaacca agatgccagt
     3661 tttggtccaa ttgagataaa ctctcttgga tttgagcaac aaaggttttg tctgattcga
     3721 aataaagcgg ttgttgcgcc atttgtccat aagcatagcc aaaagctgtg acatccacgt
     3781 catgataggc taatttgtca gcaatcacga catccccaac agcgatacct tctgctactg
     3841 ccccagctga acccgtatta ataagggcat ccacctggaa atgatcagcc aaaatcgcca
     3901 cactcatagc agacatgacc ttaccaattc cactttctac aagaacgact tcatgagaag
     3961 caatggttcc tgtatgatag gtattcccca aaacaacttg ctcctgggca ttgtctaaat
     4021 gctggaccag atgagccagt tcttctggca tagcagcaat aattcctatt ttcatttcaa
     4081 ttccttttct attacaaaag tttcattgct aaaacaagca aaatcaagag aaagatgacc
     4141 gcgaataaga ttttattcaa cttagaattg aagacatttc tcttggtatt ttcaatgcga
     4201 cggcttttat gaatagatgg ttcgacctga atcttcaagg tttcctggct aaaaccatga
     4261 tccttaggat tggcataacc aaaacgggaa gaagaggttg gtaaaatctt agtttcctca
     4321 ttatcatcca gcaaaggagg acctgaaatt ttttcgcctc tattagctct ttcaatcatt
     4381 tcatccgtta ataaagattt acccatactg acctcctcta ttttttctgc aactcccaat
     4441 actgaacagc cataattgtc ttggcatcac agatatgacc tgattggatt aattctttcg
     4501 cttcttctaa gctcacttca aggacttcca aggtttcatc ctcatcctgc ggacgcggat
     4561 tttccacttt tgtcaaatcg cttgctaaat atagttttaa cttctcatta caaaagccaa
     4621 tagctgaata aaaatcgtac aagagttcta atttccctgt ataggctgtt tcttcctcta
     4681 attcacgaag ggcagctgcc acaggggctg tgttttctcc tacctccaat tttccggctg
     4741 gaatttcgta agagacagcc tcgatagctt tgcggtactg cttgaccaag ataagttttt
     4801 gttcatccgt tactgctaaa acacagacag ccccattgtg gaaaatcaaa tcccgttggg
     4861 cagttccctt gccttctggt aattcaacct gatcttggac cagtttaaat attggtcctt
     4921 gatagatttc ttttcggcta agcgtttttt cttcaaactc catgataggc tcctactggt
     4981 tcctaggatg atgaggaaga cgtgttgcat attcgtcttt attgatctga cgaccgcgac
     5041 caatagcaat agcatctgct ggcacgtctt tagtaatagt tgaaccagca ccaacgaggg
     5101 aattgtcacc aagttctact ggtgcaataa tggttgaatt tgaaccaaca aagacattgt
     5161 ctccaatgac tgtcttgtat ttgtttttgc cgtcatagtt gactgtaata gttccagcac
     5221 cgaaattaac gttgcttccc acttcacagt ttccgatata agtcaaatga ccagccttgg
     5281 tattctcacc gattgaagat cctttcacct caacaaagtt accaatatga acttgggcac
     5341 ccagacttga atttggacga atgtgagcat aaggaccgac tgtcacaccg tctgcaacac
     5401 tactttcctc aatcatagaa ttggtaatga ccgctcctgc tccgatagtg ctgtccacta
     5461 cataagtacc gtttgtcaaa acagtctcag caccaatttt cgtttgccct ttcaaggtaa
     5521 cattggcttc gatttgaact tccggagcaa tctcaacatc aatatcgata taagttgctt
     5581 ctggattgac aaagctaaca ccattgacca tgtgtttatg attgatgcga caacgcataa
     5641 ctgactcagc tgtcgcaagc gccacacggt catttacccc aagactttca tcaaaatctt
     5701 tcaaagtata agcgccaact ttttcaccag tttcacggaa aataccaatg acgtctgtaa
     5761 tatagtattc gccttgagcg ttattggtat tgatattttt caaagcctca aacaaacgct
     5821 cgttgtcaaa gacgtatgtt ccagtgttga tttccttgat ttgcttttca aaatctgtag
     5881 catccttctg ctcaacaata cgaagaacct cagcattgtc attacgaaca attcgtccat
     5941 agccaaaagg attatccgtt tcagcagtca agatagtggc cacattttta tgattgatat
     6001 ggaaatcaat caagtttttc aagctttcac cagtgattaa aggagtatct cctgcaatga
     6061 ccaaggtgtg tcctgacaaa ccttctaaga taggctctgt catcataact gcatgaccag
     6121 ttcccaactg ttcagattga gtcacaaatt ctgtctgtcc agccaagacc tcctcaacca
     6181 attctgcctt gtgtcctaca actgttactg tcttttcagg ttggatagct cccacactac
     6241 ggaaaacatg ttccaacata gaaatacccg caaccttgtg caaaactttt ggcaaatcag
     6301 atttcatgcg agtcccttta cccgctgcta aaataatggc aaaatttgac ataatcttct
     6361 cttttctgta gaaattccct tttattatac catatttcaa atcattccgc actcttgaat
     6421 gaaaaaatgc tctaaagtct cttccttaac ccattttttt gatttttagg gtagaattat
     6481 aagatatgag aaaacaaatt catccactta ttttatttag ttttttgggg attatgatgt
     6541 tcattttaat catcaatcgc ccacttaatg acaaccaatc gtttaaaaca aaatccaata
     6601 tagcacagat tgaagcacag gctttgaaac acttagacaa accgattatt gacctctctg
     6661 gctggcagcg tcctgaggaa atcaactacg atgccctctc acaaaatatt tcaggtgcta
     6721 ttgttcgtgt tcacagtggt gctcaaacga caaaagaaaa tgatgcttca tttatcaatg
     6781 gaatagacaa ggcctataag agtcatatca ctgaacttca aaagcggaat gtcccagttg
     6841 ctgtctacgc ttatgtagct ggaaaaagtg tccaagaaat ggaaaaggct gccgaagttt
     6901 tctacaatgc tgcctctcct tacagcccta gttactattg gcttgacgtg gaagacaaaa
     6961 ccatgtctaa tatgaacgaa ggtgtcgaaa actttcgagc aaaactagca tcactaggtg
     7021 ctaaaaacat cggcatctac gttggtgtct acttcatgga agaacacagt attgatacag
     7081 gcaagtttac ctctatttgg attccgtcct acggctcaga ctcaggattt ttggagagca
     7141 gtcctaaaac tgatttagat tatgatattc accaatacac atctaaagga aaaattgccg
     7201 gctttgacca cgatttagat atcaacgtta tctctccctt aaaaaataaa gaagaaacct
     7261 ttcgaaaact ttttttaaaa ccttaaaagc atttgtttat catttgcttt ttctttttgt
     7321 gtctgattgt gatacaatat agtaaggatt ttttgaaata gaaatagttg gaggaaatat
     7381 atgctctcat ggttagcacg cgttattaaa ggaattgtga ttgctcttgg atttatccta
     7441 ccgggaattt ccggaggggt tctagcagca atcttaggaa tctatgaacg aatgattggc
     7501 tttctggctc atccctttaa agaccttaaa gaaaatgttt tgtactttat tccagttgcc
     7561 atcggtatgc ttctgggaat cggcttattt tcctacccga ttgaatacct gcttgaaaat
     7621 tatcaggtct ttgtattatg gagctttgcg ggagctatta tcggtacagt tcctagcctc
     7681 ctcaaagaat caactcgaga atctgaccga gacaagattg atttagcttg gttatggaca
     7741 acctttatca tttctggatt aggactctat tccttaaatt ttgtcgttgg aaccttaagc
     7801 gccagctttc ttaacttcgt cctagcaggc gcactattgg cccttggcgt cttggttcct
     7861 ggcctcagcc catcgaattt acttttgatt ttgggactct atgctcctat gttgactggt
     7921 tttaaaactt ttgatctctt gggaaccttc tttccgattg gaattggtgc aggtgcaact
     7981 ctcatcgttt tttcaaaatt gatggattat gccttaaaca actaccactc acgcgtctat
     8041 catttcatca tcggtatcgt cctatcaagt acccttttga tcttaattcc aaatacagga
     8101 aacgctgaaa gtatccaata cacaggactt tcacttgtcg gttatgtcat catcgccttc
     8161 ttctttgcgc tgggaatctg gcttggtatt tggatgagtc aattggagga taaatataaa
     8221 taatggcaaa aaaagttaaa atcaaaaaaa cattggtgga acaaatccta tctaaagcag
     8281 ctatccctca tcaggggatt caaatcaatg ccctagaagg agagcttcct caaggttatg
     8341 aacgagatca gattttcaaa accttggcgc ttttgggaga caagaccgga ccgattatcg
     8401 gaattgtccc tatcactcag cacttgtctg aaaagaaact agctaaaatt tctggcaata
     8461 aaaaagtgag catgattcca caaaaggact tagaaaaaac aactggttac attcatggag
     8521 ccaataatcc tgtcggaatt cgtcagaaac acaattatcc catttttatc gataaaattg
     8581 ctctagattt ggatcgaatg attgtctctg caggcgaagt cggacacagc attatcgtcg
     8641 cgccacaaga cttggctagc tttgtaaagg cagactttgt agatattttg gaggacatca
     8701 agtaatgaaa ctctactttg tccgccacgg tcgtaccctc tggaaccaag aaggtcgttt
     8761 tcaaggtgct agcggtgatt ctcctcttct tcctgaatcc attgaaaccc taaaacgact
     8821 tggccagtat ctcaaggaaa ttccttttga tcagatttat tcaagtgatt tacctcgagc
     8881 ggtcaaatct gctgagatta tccaaagtca actccatacc ccctgttctt tagaaatcgt
     8941 tcctaatctc cgtgaatggc aacttgggaa gttagaaggt ttgaaaattg caaccttgga
     9001 agctatttac ccgcaacaaa tccaggcttt tcgttcaaat cttgctcaat ttgacactcg
     9061 aatgttcgga gccgaatccc tctatagtac aactcagcgg accatccaat ttatcaaatc
     9121 attaaaagat agtccagctg atcgtattct aattgtcgga cacggcgcca atcttactgc
     9181 cagtcttcgt actctcctag gctataaaga accacttctt cgtaaagatg gcggtctagc
     9241 aaatgccagc ctgaccatta tagaaaccca tgattttgaa acattcactc tcaatacttg
     9301 gaatgatact tcttatcaat cataattata gcctagcctt ctgaactaga accataggag
     9361 atatagtcag ttgaaacaaa aataagacaa aagaaccttg taaaaaggta ttgcaacttg
     9421 ccaatacctt tttgatatga acacgtgtct tctcaacagg attgtagagc aaaatgaaat
     9481 aagaactgaa taatatgatt tgagaattta aatcaattta taagaatgtt ttagaagcag
     9541 ttatgtacta ttttagattc acttttctat actaagatga gtagggagga aaaggtaaaa
     9601 gtttatgccc aaattcttca cataagaact ctagcttacc cattctatgg aatcttgcat
     9661 tatccattaa aacttccaga ctcataccct tctaaaatct attcaaacca cgtcagcttc
     9721 acattatata tgttggtgac ctcacaagtt ttatctacaa cctcaaagct gttctttgag
     9781 cagcctacag ctagcttcct agtttaatct ttgcttttca ctgagtatca agttaaaaaa
     9841 atgaggctgg tcaaaaagtc tttaaaataa aaaacgcata ttatcaggtg ttaaatgaac
     9901 tgcaccccaa aagttagaca gaaaaaatct aacttttggg gtgtttttat tatgaaatta
     9961 acttatgatg ataaagttca gatctatgaa cttagaaaac aaggatatag cttagagaag
    10021 ctttcaaata aatttgagat aaacaattct aatattaggt acatgattaa attgattgat
    10081 cgttaatgtt ggaacaggca ttcaaagaga agcactacga gaatacgatt ctccatagtg
    10141 accaaggctg gcaatatcaa cacgattctt atcatcggtt cctagagagt aagggaattc
    10201 aagcatctat gtcacgcaag ggaaacagcc aagacaacgg tatgatggaa tctttctttg
    10261 gcattttaaa atccgaaatg ttttatggct atgagaaaac atttaaatca cttaatcaat
    10321 tggaacaagc cattatagac tata
//
LOCUS       DBERAE010000057        10158 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.57, whole genome shotgun sequence.
ACCESSION   DBERAE010000057 DBERAE010000000
VERSION     DBERAE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.57"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(98..334)
                     /gene="rpsT"
                     /locus_tag="ACL70N_001947"
     CDS             complement(98..334)
                     /gene="rpsT"
                     /locus_tag="ACL70N_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGS0590688.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(402..1322)
                     /gene="coaA"
                     /locus_tag="ACL70N_001948"
     CDS             complement(402..1322)
                     /gene="coaA"
                     /locus_tag="ACL70N_001948"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGS0590689.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDSDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1512..1915
                     /locus_tag="ACL70N_001949"
                     /pseudo
     CDS             1512..1915
                     /locus_tag="ACL70N_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2122..2712
                     /locus_tag="ACL70N_001950"
     CDS             2122..2712
                     /locus_tag="ACL70N_001950"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0590690.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            2709..3986
                     /locus_tag="ACL70N_001951"
     CDS             2709..3986
                     /locus_tag="ACL70N_001951"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGS0590691.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            4004..4666
                     /gene="deoC"
                     /locus_tag="ACL70N_001952"
     CDS             4004..4666
                     /gene="deoC"
                     /locus_tag="ACL70N_001952"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGS0590692.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4653..5042
                     /locus_tag="ACL70N_001953"
     CDS             4653..5042
                     /locus_tag="ACL70N_001953"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0590693.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5132..6184
                     /locus_tag="ACL70N_001954"
     CDS             5132..6184
                     /locus_tag="ACL70N_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGS0590694.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6328..7863
                     /locus_tag="ACL70N_001955"
     CDS             6328..7863
                     /locus_tag="ACL70N_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590695.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINMHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7856..8914
                     /locus_tag="ACL70N_001956"
     CDS             7856..8914
                     /locus_tag="ACL70N_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590696.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLTELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8917..9873
                     /locus_tag="ACL70N_001957"
     CDS             8917..9873
                     /locus_tag="ACL70N_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590697.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9958..>10158
                     /locus_tag="ACL70N_001958"
     CDS             9958..>10158
                     /locus_tag="ACL70N_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0590698.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMI"
BASE COUNT         2918 a         1793 c         2330 g         3117 t
ORIGIN      
        1 atttttatcg ctctgaacat caaaaaagaa aggacgaaat ttgtcctttc tcaagcttag
       61 cttttcttca acccactaca gttgacaaag agccttctta tttagcaagt ttagctgaaa
      121 gacgagcttt atcgcggctt gctttgtttt tgtgaatcaa acctttagtt tctgctttat
      181 cgatagctga gctagcagca cggaaaagtt cttcagatgg gtttgcttcg aaagctttta
      241 tagcagtacg catagctgat ttttgagctg agttcttttc gttttgttta acgttcaatt
      301 cagcgcgttt gatagctgat ttaatgtttg ccaatgttct tacctccata tttactaact
      361 ataccattat atatgaaaac ttacgttttg acaagggaaa attatttttt taagtaaatt
      421 tcatcgattt catggttctt gcttttatga agaatcactt ctgcacgatt tctggttggt
      481 tcaatataat tttgtagatt tgtgagattg atactggtcc agacctgatg ggcaaaggct
      541 tccacttccc caatcggcat ctgagtaaaa cgataatagt agctatcaga gtcgttttgg
      601 gctagactca gcattttcaa gaaacggtcc agataccaac tttcaatatc atccactcca
      661 gcatctacat agatggaaaa gtcaaagaag tcagtgatat agagacgatc gttttgtgga
      721 ttttgaaaga cattgattcc ctcaacaatt acaaaatcag cagctttgac actttgtttc
      781 tcttcgggta cgatgtcgta aacttcatga gaatagacag gaatatctac atcttgtcca
      841 tttttgatgc ggtccaagaa gttgagaaga gcttccatat catagctttc aggaaatcct
      901 ttacgattta aaatcccctg ctcaatcaag gtttgattgg gatagagaaa accatcagtt
      961 gtaaccaact caaccgtagc atctgtaaac gtacgggaca gtaggatttg aagtaggcga
     1021 ctggttgtgg attttccaac ggcaacactc ccagaaaccc caataataaa aggttgagat
     1081 ttactttcac gttggaggaa aattcctttt gaaaaggcta aatcttcctt agttcgcttg
     1141 taaatctgaa tcagatgagc caaggggaga tagatatctg taacgtcttg gagactgatt
     1201 tggtcattaa aactcttgat agattccaat tcttcttctg tcaaaggagg tgttgtcttt
     1261 cgatgtaaag attgccaagt ctggcggctg attttttcaa aatgtaaaaa ttcgttggtc
     1321 atttgttttc ccctagatat tttgtctatc ataccataaa aagctaaaaa aataaagcgg
     1381 tttcttgaat gtggtaagtc aatggtatat agtataagtg atcaatttat tgatgaaata
     1441 ggagatagat tctactgatt tataagctta taaagggggc tttttagttc acaacttata
     1501 ggaggtgtac tatgaaaatc ttaaaacgtt acatattgga actctgtttt attttaagtt
     1561 ttgctttacc ttttataaaa ggagccaatg cagataatgg tagatgcttt gtggaaacct
     1621 attacggttt tacttttttg atggaacatg ctattgtaac agctgtcttt atctgttcgt
     1681 tcttaattgc tttcttacta aaaaacgatg ggcgaaatgg attgctgcgg gtagttattg
     1741 ctttttagtc ctacggattg cgacagaggg ttatttcttc cacatgtcac tagaagattt
     1801 gatacgactt tggacaagtt tggaaatcct gacacaaacg tatcagttgg gcttttatct
     1861 aaacattttg ttaggaattt tgttgataat aaagtatttt aaggttaagc aatagaaata
     1921 ataatctgcc tgattataga tgataaactt tttgttttta tctggactgt gatatttata
     1981 gttctaaatg gtttattatt tataagtgtt gaaagagatt gaagaaaatg gcttcgtgac
     2041 ttgctttctt cggtcttttt cgttttatta tcaatttgta aacgatttac aatttgagtc
     2101 aaattatggt aaaatagtgt catgagtaaa atgtactatg cagaaaatcc tgacgctgct
     2161 cacgacattc atgagttgag agtggacttg ttgggagaaa aaatgacttt tttgacagat
     2221 gcgggtgttt ttagcaagaa aatggttgac tttggaagtc aactcttgct caagtgtctg
     2281 gatgtcaacc aaggagagac agtcctagat gtaggctgtg gctatggtcc attaggtttg
     2341 tccttggtca aggtttacgg agttcaggcg accatggttg atattaacac tcgtgccctg
     2401 gatttagctc agagaaatgc tgaaaaaaat aatgcaaaag cgacgatatt tcaatctaat
     2461 atttatgcaa gagttcaagg gcgatttgac catgtcattt ccaatcctcc tatccgtgcg
     2521 ggcaagcaag tcgttcatga aatcatcgag aaaagtaaag atttcttgga aattggtgga
     2581 gatttgacca tcgtcatcca gaaaaaacaa ggagctccaa gtgccaagtc taagatggaa
     2641 gatgtgtttg gcaattgtga aatccttaaa aaagacaagg gatactatat ccttagaagt
     2701 gtgaaagaat gagagcagtt gatttaatcc aaaaaaaacg agacggtcaa gaactgactt
     2761 caagtgaaat tgaatggctg atagaaggct atgtatcagg aactgttcct gattatcaga
     2821 tgtctgcctt tgctatggct gtttatttta aaggaatgac gactcgagaa atctctgatt
     2881 taacgatgaa tatggttaag actgggcaag agtttgacct gtcagccatt gatggtgtga
     2941 aagttgacaa gcattctact ggtggtgtcg gcgataaggt aaccttgatt ttagctcctc
     3001 ttgttgctag cttcggtgtg cctgtagcaa aaatgagtgg tcgtggtctt ggccatacag
     3061 gcggaacaat tgataaattg gagtccatta agggctatca agtagaacgt agtcaagagg
     3121 attttattcg tcaggttcag gatattggag tatctgtcat tgggcaatca gaccagctgg
     3181 tcaaagcaga taagcttctc tatgcccttc gtgatgtgac cgcaactgtc gacacgattc
     3241 ctttgattgc gagttcggtg atgagcaaga aaattgcggc aggggcggat gctattttgc
     3301 tagacgtgac tgtcggtgag ggtgccttca tgaagacggt tgatgaggcg cgtgagttgg
     3361 ctcaaactat ggtagatctt ggtaaggttg ttggacggaa gacagtagca gtgattacgg
     3421 atatgagcca gcctttggga cgagcgattg gaaatcgtct ggaaatcctt gaagcattgg
     3481 agattttgca aggtcaagga cgtcaggata ttacccactt tatttgtgaa ttggctcaaa
     3541 ttatgcttgg tttggcaaat gttaacaaaa ctgttgaaga agttcgccaa catcttgaaa
     3601 atggtcaagc actggctaag tttgaggaaa tggtgcaagc ccaaggtgga gacttggaag
     3661 acctctatcg tcctgtaaat gtagctcatg tggtggaaat ccctgctcag gaaacgggtg
     3721 tcatttcagc tcttccagct atggactttg gtctttatgc catgaggctg ggtgctggtc
     3781 gtgcagttaa gtctgatgtc ttggactatg aaacaggaat tgtttttgaa aagaagattg
     3841 gagactccgt tcaaaagggt gaaattgttg caaaagtata cacaaatgaa aaaattccac
     3901 ctcaactagt tacagatttc caaaaatgtg ttaaaataag tgatgaagtg aaaaaaatcc
     3961 gtgaaattgt agaaatcatc tcctaaatgg agggaaaacc gaaatgaaat taaataaata
     4021 tatagatcat acgcttttaa aacaagatgc aaagaaaaaa caaattgata gtttgttgtc
     4081 tgaggctaga gagtatgact ttgccagtgt ttgcgttaat ccgacctggg ttgaacatgc
     4141 taaaaaagga cttgaaggca cagatgttaa ggtttgcaca gtagtaggtt tccctttggg
     4201 agcaacaact tcagccgtga aagcatttga gacaaaagaa gctatccaaa atggtgcaga
     4261 tgagattgat atggtgatca atgttggagc tctcaaatca ggtaatttag ccttggttga
     4321 gtcagatatt cgcgcagtag tggaagcaag tggtgataag ttagtgaaag tcattattga
     4381 agcttgcctt ctgacagacc aagaaaaaat tgttgtttgc caattggccc aaaaagctgg
     4441 ggctgacttt gttaaaacat ctactggctt ttcaactggt ggtgctacga tagcagatgt
     4501 tagattaatg cgtgaaacag ttggatctga tatgggagtc aaggctgctg gtggagctcg
     4561 ttcttatgca gatgctcttg cctttgtcga agcaggtgcg acccgtatcg gaacgtcagc
     4621 tggggtagct attttaaaag gagaattggc agatggcgac tactgagttg attgaactgg
     4681 caattgaaac cagcaaacat gcctatgtcc cctattctca ctttcctatc ggagcagttt
     4741 tagtagccaa agacggaagt gtttacacgg gagtgaatat cgaaaatgct agctatcctt
     4801 tgaccaattg cggtgagaga acagctgttt ttaaggctat atctgaaggc caaagagaat
     4861 tttcagaatt gattgtctat ggtcaaactg aaaaaccgat ctcgccatgt ggtgcttgtc
     4921 gccaagtaat ggtcgaattt tttgaacaag atttaaaagt gaccttagtc gcaaaagata
     4981 aatcgacggt cgagatgacg gtcggggaat tacttccata ctcttttaca gacttaaact
     5041 agtctgagtc gctctctgag tggcacggtc cttgtggcca accaatccat acttgcaaca
     5101 tcgttgcaca tcttatttag gaggttcagt aatgaacaag aaacaatggc taggccttgg
     5161 tctagttgca gtggcagcag ttggacttgc tgcatgtggt aaccgctctt ctcgtaacgc
     5221 agcttcatct tctgatgtga agacaaaagc agcaatcgtc actgatactg gtggtgttga
     5281 tgacaaatca ttcaaccaat cagcttggga aggtttgcag gcttggggta aagaacacaa
     5341 tctttcaaaa gataacggtt tcacttactt ccaatcaaca agtgaagctg actacgctaa
     5401 caacttgcaa caagcggctg gaagttacaa cctaatcttt ggtgttggtt ttgcccttca
     5461 taatgcagtt gaagaagcag ctaaagaaca cactgacttg aactatgtct tgattgatga
     5521 tgtgattaaa gaccaaaaga atgttgcgag cgtaactttc gctgataatg agtcaggtta
     5581 ccttgcaggt gtggctgcag caaaaacaac taagacaaaa caagttggtt ttgtaggtgg
     5641 tatcgaatct gaagttatct ctcgttttga agcaggattc aaggctggtg ttgcgtcagt
     5701 agacccttct atcaaagtcc aagttgacta cgctggttca tttggtgatg cagctaaagg
     5761 taaaacaatt gcagccgcac aatacgcagc cggtgcagat attgtttacc aagtagctgg
     5821 tggtacaggt gcaggtgtct ttgcagaggc aaaatctctc aacgaaagcc gtcctgaaaa
     5881 tgaaaaagtt tgggttatcg gtgttgaccg tgaccaagaa gcagaaggta aatacacttc
     5941 taaagatggc aaagaatcaa actttgttct tgtatctact ttgaaacaag ttggtacaac
     6001 tgtaaaagat atttctaaca aggcagaaaa aggagaattc cctggcggtc aagtgatcgt
     6061 ttactcattg aaggataaag gggttgactt ggcagtaaca aacctttcag aagaaggtaa
     6121 aaaagctgtc gaagatgcaa aagctaaaat ccttgatgga agcgtaaaag ttcctgaaaa
     6181 ataatggatg gaagtcattt cttaggaagc ggccaagggc cgctttttta agagttgaga
     6241 caaagtcatt ttgtctcagt aaagcttgct actagacaaa ctagcaagtt ttattgaaat
     6301 aaaataagac tctgaaagga agagcacatg gcacacgaaa atgtcattga gatgcgtgat
     6361 attaccaagg tgtttggtgg atttgttgcc aacgacaaaa tcaacatgca cctacgaaaa
     6421 ggtgaaattc atgcactttt aggagaaaat ggggctggta agtccacgct aatgaacatg
     6481 ttagcaggcc ttcttgaacc aactagtggt gaaatcgcgg tcaacggtca agttgtcaat
     6541 ctcgactccc catctaaagc agctagcttg ggaatcggga tggttcacca gcactttatg
     6601 ttggttgaag ccttcacagt ggctgaaaat atcattttag gtagtgaatt gactaaaaat
     6661 ggtgtgctag atatcgctgg agctagcaaa gaaatcaagg ctctttctga acgttatggc
     6721 ttagctgttg acccttctgc caaggtagca gatatctcag ttggagccca acaacgtgta
     6781 gaaattttaa aaacacttta tcggggggct gatatcctta tctttgacga accaacggct
     6841 gttttgactc catcagaaat tgatgagttg atggctatta tgaaaaatct tgtcaaagag
     6901 ggaaaatcaa ttatcttgat tacccacaaa ttggatgaaa ttcgagcagt ttctgaccgt
     6961 gttacagtta tccgtcgtgg gaaatcaatt gaaaccgttg aaattgcagg ggctaccaat
     7021 gctgatttgg cggaaatgat ggtaggacgt tctgtttcct ttaaaacaga gaagcaagcc
     7081 tctaaaccaa aagaagtggt tttgtctatc aaagatttgg tggtcaatga aaaccgtggt
     7141 gttccagctg ttaaaaatct gtccttggat gttcgtgctg gagagattgt tggtattgcg
     7201 gggattgatg gaaatggtca gtctgaactg attcaagcca ttacaggtct tcgtaaggtt
     7261 gaatctggta gcattgagct aaaaggagat tcaattgtag gcttgcaccc acgtcagatt
     7321 acagaactaa gtgttgggca cgttccagaa gaccgtcacc gtgatggctt gattttggaa
     7381 atgatgatat ctgaaaatat tgcccttcaa acctactata aagaaccaca tagtaaaaat
     7441 ggaattttga actattcaaa tattacttct tatgctaaaa agctgatgga agagtttgat
     7501 gttcgcgctg ccagtgaatt agttcctgca gctgcactct caggaggaaa tcaacaaaaa
     7561 gcaattattg ctcgtgaaat tgatcgagat cctgatctcc ttatcgttag tcagccaact
     7621 cgtgggttgg atgtcggtgc cattgagtat atccacaaac gcttgattga agagcgtgat
     7681 aatggcaagg ctgtccttgt tgtcagcttt gaattggatg agattttaaa cgtctcagac
     7741 cgtattgccg ttatccacga tggtaagatt caaggtattg tatcaccaga aacaaccaat
     7801 aaacaagaac ttggtgtctt gatggctggt ggaaacttgg gaaaggagaa gagtgatgtc
     7861 taaaaaatta caacaaattt cggttccctt gatttctgta ttcctaggaa ttttactcgg
     7921 agccattgtc atgtggatct tcggttatga tgctatttgg ggctacgaag aattgttcta
     7981 tacagccttt ggcagtctgc gtgggattgg agaaatcttc cgtgctatgg gtcctctggt
     8041 cttgattggt cttggttttg ccgttgccag tcgagctggt ttctttaacg tcggacttcc
     8101 tggtcaggct ttggcaggtt ggattctcag tggttggttt gccctgtcgc atccagatat
     8161 gccccgtccc ttgatgattc tagcaaccat cgtgattgcc ttgattgctg gtgggattgt
     8221 cggagcgatt ccaggtattc ttagggccta tctagggacg tcagaggtta ttgtaaccat
     8281 catgatgaac tacattgtct tgtatgtagg gaatgccttt atccatgctt tccctaaaga
     8341 cttcatgcaa agtacagatt cgaccattcg tgttggggct aatgcaacct atcagacacc
     8401 ttggttgact gagttgactg gtaactcacg gatgaatatt ggtattttct ttgccatcat
     8461 tgccgttgca gttatttggt tcatgctcaa gaaaacaact cttggttttg aaatccgtgc
     8521 agttggtctt aatccacatg cttcagaata tgctggtatt tctgccaagc ggactattat
     8581 cctatctatg attatttcag gtgccttggc aggtcttggt ggagctgttg aaggtttggg
     8641 aaccttccag aacgtctatg ttcaaggttc gtcattagct atcggattta acggaatggc
     8701 ggttagtttg cttgcggcca actcaccaat tggtatactc tttgcagcct tcctatttgg
     8761 cgttctccaa gttggggctc ctggtatgaa tgcggcgcag gtaccatctg agcttgtcag
     8821 cattgtaaca gcgtctatta tcttctttgt cagtgttcat taccttatcg aacgctttgt
     8881 caaaccgaaa aaacaagtta aaggaggtaa gtaaagatgt ctattataac cttgctcccc
     8941 ctcttggtgt cttctatgct gatttactca gcacctctca tctttacaag tatcggtggt
     9001 gttttctctg aacgtggtgg tgtggtaaac gttggccttg aaggaattat ggttatgggt
     9061 gccttttctg gagttgtctt taaccttgaa tttgcagaac aatttggagc agcaactcca
     9121 tggctatcct tgcttgtagc aggattggtt ggtagtgttt tctctatcat ccacgcagca
     9181 gcgacggttc atttccgtgc agaccatgtt gtcagcggta cggtattgaa cttgatggcg
     9241 cctgccttgg ctgttttctt agttaaagtt ctttataaca aaggacaaac cgacaaccta
     9301 agtcaaactt ttggacgctt tgatttccca gtcttggcaa atatcccagt gattggtgat
     9361 atcttcttca agtcaactag tctacttggt tatctggcga ttgccttctc attccttgct
     9421 tggtttattc tctttaagac tcaatttggt cttcgtctcc gctctgtcgg tgaacatcct
     9481 caagcagcgg ataccttggg aatcaacgtc tacaagatga gatatttagg ggttattatt
     9541 tcaggttttc taggtggaat tggcggagcg atttatgcgc aatcaatctc agttaacttc
     9601 tcagtgacaa ctattgttgg acctggattt atcgcccttg ctgcgatgat ctttgggaaa
     9661 tggaatccaa tcggtgctat gctttctagt ctcttctttg gactttcaca aagtttggct
     9721 gttatcggtt ctcaattgcc gttcctacaa ggagtgccag cggtttatct tcaaattgca
     9781 ccttatgttt tgacaattct tgtcttagca gccttctttg gaaaagcagt cgcaccaaaa
     9841 gcagatggta tcaactacat caaatcaaaa taagcataca aaaaaacgtc agtccaatga
     9901 ctgaactaca ccccaaaagt tagacagaaa aaatctaact tttggggtgt ttttattatg
     9961 aaattaactt atgatgataa agttcagatc tatgaactta gaaagcaagg atatagctta
    10021 gagaagcttt caaataaatt tgggataaat aattctaatc ttaggtacat gattaaattg
    10081 attgatcgtt acggaataga gttcgtcaaa aaagggaaaa atcgttacta ttctcctgat
    10141 ttaaaacaag aaatgatt
//
LOCUS       DBERAE010000058        10099 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.58, whole genome shotgun sequence.
ACCESSION   DBERAE010000058 DBERAE010000000
VERSION     DBERAE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.58"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..364
                     /locus_tag="ACL70N_001959"
     CDS             <1..364
                     /locus_tag="ACL70N_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0590699.1"
                     /translation="VLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSILSKSLQ
                     RANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSIYTHVTK
                     NMKDEAINVLDKVMKKIF"
     gene            complement(502..1806)
                     /gene="eno"
                     /locus_tag="ACL70N_001960"
     CDS             complement(502..1806)
                     /gene="eno"
                     /locus_tag="ACL70N_001960"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGS0590700.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            1970..2416
                     /locus_tag="ACL70N_001961"
     CDS             1970..2416
                     /locus_tag="ACL70N_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGS0590701.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2413..3528)
                     /locus_tag="ACL70N_001962"
     CDS             complement(2413..3528)
                     /locus_tag="ACL70N_001962"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGS0590702.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3537..3866)
                     /locus_tag="ACL70N_001963"
     CDS             complement(3537..3866)
                     /locus_tag="ACL70N_001963"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGS0590703.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3811..4182)
                     /locus_tag="ACL70N_001964"
     CDS             complement(3811..4182)
                     /locus_tag="ACL70N_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGS0590704.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4241..5674)
                     /gene="glgA"
                     /locus_tag="ACL70N_001965"
     CDS             complement(4241..5674)
                     /gene="glgA"
                     /locus_tag="ACL70N_001965"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGS0590705.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHIHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWLAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5671..6810)
                     /gene="glgD"
                     /locus_tag="ACL70N_001966"
     CDS             complement(5671..6810)
                     /gene="glgD"
                     /locus_tag="ACL70N_001966"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGS0590706.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6800..7942)
                     /locus_tag="ACL70N_001967"
     CDS             complement(6800..7942)
                     /locus_tag="ACL70N_001967"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGS0590707.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7932..9860)
                     /gene="glgB"
                     /locus_tag="ACL70N_001968"
     CDS             complement(7932..9860)
                     /gene="glgB"
                     /locus_tag="ACL70N_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGS0590708.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPNVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLICIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3060 a         2229 c         1783 g         3027 t
ORIGIN      
        1 tgttcttgtt tcaattgact atataaattg tctaagcgaa acaaccgata agaattggca
       61 caaaagcgac cgtgtttttg ttaccaatac aggaaaaaca gttcatagtt ctatcttgag
      121 caagtctctc cagcgagcaa acgaacgcct taaaaaacca attcccaaac atctgtcccc
      181 tcacatcttc agacacacca ctattagcat cttatcagaa aataaaattc ctttaaaaac
      241 aatcacggac agggttggtc attccgactc tgaagtcact acttccatct acacccacgt
      301 cacaaagaac atgaaagatg aagcaatcaa tgtactggat aaagttatga aaaagatttt
      361 ttaaaaagtt ttgccccttt tttgtcctct aaatacaaaa atagcccttc ggataaaatc
      421 cgaggggcta gaaacgttgt taaatcaacg gccgaacttt tgaatttcat ggttcgggat
      481 aaaatagttc actgaactat tttatttttt aaggttgtag aatgatttca atccacgata
      541 ttcagctact tcaccaagtt ggtcttcgat acgaagcaat tggttgtatt tagcgatacg
      601 gtctgtacgt gaaagtgaac cagtcttgat ttgtcctgcg ttagttgcaa ctgcaatatc
      661 agcgattgtt gaatcttcag tttcacctga acggtgtgat acaacagcag tgtaaccagc
      721 ttctttagcc atttcgatag cttcaaaagt ttcagtaaga gtaccgattt ggttaacttt
      781 gataaggatt gagttagcag caccttcttg gataccacgt gcaaggtagt cagtgtttgt
      841 tacgaagaag tcgtcaccaa caagttgtac tttcttacca agacgttcag taagagcttt
      901 ccaaccatcc cagtcgtttt catccatacc atcttcaata gtgatgattg ggtatttgtt
      961 aaccaattct tcaaggtagt cgatttgttc tgcagatgta cgaacagcag caccttcacc
     1021 ttcaaattta gtgtagtcgt aaactttacg ttctttatcg tagaattctg atgaagcaca
     1081 gtcaaatccg ataaatacgt ctttacctgg tacatatcca gcagcttcaa tcgcagcaag
     1141 gatagtttca acaccatctt cagttccttc gaaacgagga gcgaatccac cttcgtcacc
     1201 tacggcagtt tccaaaccac gtgatttaag gattttctta agagcgtgga agatttcagc
     1261 accgtaacga agggcttctt taaatgttgg cgcaccaact ggcaagatca tgaactcttg
     1321 gaaagcgatt ggagcgtcag agtgagaacc accgttgatg atgttcatca ttggagttgg
     1381 aagaacttta gtgttgaatc caccaaggta gctgtaaagt gggatttcaa ggtagtcagc
     1441 agcagcacga gctacagcga tagacacacc gaggattgca ttcgcaccca atttaccttt
     1501 gttaggagta ccgtcaagtg cgatcatagc acggtcaata gcttgttgat cacgtacatc
     1561 gtagccaatg atagcttcag caatgatgtt gtttacgttg tcaacagctt tttgtgtacc
     1621 aagaccaccg taacgagatt tgtcaccgtc gcgaagttca actgcttcgt gttcaccagt
     1681 agaagctcct gatggaacca taccacgtcc gaaagcacct gattcagtgt aaacttctac
     1741 ttcaagtgtt gggttaccgc gtgagtctag gacttcgcga gcgtaaacat cagtaataat
     1801 tgacattttt tactctcctt atgagttaaa ttttttacac ctctataata ccttaaaacc
     1861 cctccttttt caagaaaaaa cgttatcttt gtgcaacttt tccttaactt tataaagtaa
     1921 tcgctttctt ttgtctgttt tattctaact tttatgatat actgttttca tgacagattt
     1981 atcaaaacaa ttacttgaaa aagctcatgg tgggttaaaa ataaatccgg atgaacaaag
     2041 acgctatctt ggtacttttg aggaaagagt tcttggatat gtagatattg acacagcaaa
     2101 tagccctcag ttagaaaaag gctttttatt tattttagaa aaccttcagg aaaaagcaga
     2161 gccactattt gtgaagattt caccaactat cgaatttgat aagcaagttt tctacttaaa
     2221 agaagcaaaa gaaactgata gtcaagccac catagtatct gaagagcata ttacttctcc
     2281 ttttggcctg gttattcata gcaatgcacc agttcaagta gaagaaaaag accttcgact
     2341 tgcttttcca aaactttggg aagttaaaaa ggaagaacca gccaaaacat ccttatggaa
     2401 gaaatggttt agctaaatct tgcacatatt taataagtgc ccaatattgg cagccgtgcg
     2461 ctccagatag agactggcat ttttcaaact atcttctaaa ggttcacttt tctccaaaat
     2521 agaaaagaca gcttggatat tttcaaatgg taggggaggt aaatcttcag caagactacc
     2581 gcaaatagca ataacaggaa ctccaacagg ggttcttttt gcaacaccta taggcgcttt
     2641 cccagcaaag ctttgactat caagtcttcc ttctccaaca acaaccaagt cagcatctga
     2701 aactttctta tcaaagttga ttaagtccaa gcaggtatca attccagaca cgatacttgc
     2761 ctgagcaaag gcacacaaac caccagcaag gcctccacct gctcctgctc ctttaatttc
     2821 taatgttgca ggtgagaatt tttcataaaa atcttggatc gcctgatcta cgactgcaaa
     2881 catagtcgga tgtagacctt tttgattgcc aaaagtgtaa gtcgcacctt gatgaccaca
     2941 taagggactc acgacatctg ctagaatatg aatttgaaca ccttcaggaa ttttatagca
     3001 attttctgtt gaaacagaag ctaagtttaa taaggattga tcggaagcag gcaagacatt
     3061 tccatcccta tcataaaatt gataacctaa accagcagca atccccagtc ctccatcatt
     3121 actggccgtg ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag
     3181 aatcaactct ccaataccac aagtttggat ttgaagtgga tttcgtttct ctagcggaat
     3241 ttttccaaga ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata
     3301 gcgcatggct tctttttgtc caaaagggtc tgtcacttgg atccattttt cttttaggtc
     3361 aagagaatgt cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag
     3421 acattctaca tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg
     3481 agctgtcaag ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat
     3541 tctaaacagt caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt
     3601 atttcttttt tgagcatttc tttggaacaa aaggcgattc ctaactccgc cgacttcaac
     3661 attaatagat tattgacccc atcaccgatt gccaccgttc tttctttaga aagttttagt
     3721 ttctttctcc atttttccag agtttctttt ttgacctggg gacttataat ttgtccaact
     3781 aattttcctg ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata
     3841 ccaagggatt ttgctaatct ctccaactat tggtgtaaat ccaccagaca ccagaccaac
     3901 taggatgcca ttcttttgga gaatagagat gaactctggg acatttagcg atagatgaat
     3961 tgagttgaag acgttatcaa agaccaaaat aggaagacct tccaacaagg acactctttt
     4021 tcttaaactg ctttcaaaga ccaactctcc tcgcattgct cgacttgtaa tctgcgaaat
     4081 ttccgcctca tgacctgcct ctctccctaa aagatcaatc acttcttcta ggattaaggt
     4141 tccatctaca tccaaaacac acaagccttt tacttgagac atcagttctc ctctctaaac
     4201 agcctaaaaa tcgtatgaag tcatcatacg attttatcta ttaattaact aaactatggt
     4261 acaagtcaag gtatgacttg caggctgtat cccatgagaa gtcactctcc atagcttgtt
     4321 tttgtaggtt tctccaaatg tctggatggt ttctatacaa gtccaatgct gtttggaaag
     4381 tccaatttaa ccaataagga gatagattgt caaagctaaa gccagtaccg cttccttcga
     4441 ttggattgaa agcgcgaact gtatctcgca agcctccaac ttcatggacc aatggcaagg
     4501 ttccataacg catagccatc atttgagaca agccacacgg ttcaaaacga cttggcatga
     4561 ggaagaggtc acaagcagcg tagatttcct gagcaagttt gacatcaaaa gtgatatttg
     4621 ttgatagctt gtctgggtaa atctgagcca accatgagaa agctccttca aaggctggat
     4681 cgccagttcc caaaagaaca atctgaacat cttcttgcaa gatatggtga agactttcga
     4741 ccaccacatc aaaacctttt tgacgtgtca aacgagaaac aattcccacc agtggaacgt
     4801 ctgctctaac aggcaagcca actctttctt gcaattttgc cttatttttg gctttcccag
     4861 acaaatcttc ctgattgaaa tgatagtcta aaagagcatc cgtctgagga ttataaagat
     4921 cagcatcaat cccattcacg ataccagata ctttaccaga ctccatttta agaatctgat
     4981 ccaaattaca tccaaactga ctagtcataa tttcatgagc atagctaggt gaaacggttg
     5041 aaacacggtt cgcatagaga atacctgcct tcatccagtt cagacagttg ttccatcgaa
     5101 gggtgccatc agcgtaacgt tcaaggccaa ctccaaacaa atcacccaac attccttctg
     5161 aaaattgtcc ttggaattct aaattatgaa tggttaaaac tgtttcaatg tcctcatagg
     5221 cttgaatcca acggtatttt tccttcaaca agaaaggaat catagctgta tggtagtcat
     5281 gaatatggag aagatcagga ataaagtcaa tcctttccat agcctcaatg gcagccagtt
     5341 ggaaaaaggc aaagcgttct ccgtcatcaa aatcaccgta aacatgacca cggaagaaat
     5401 aatattgatt gtcaataaag tagaaggtta caccatttaa tactgttttc ttaattccac
     5461 aatactgtct gcgccaacca acgctcacct caaaatgaag cacatcttca atctgatttc
     5521 caaatttagc ctctaccata tcatagtagg gtaaaatcac tgcaacttcg tgcccagctt
     5581 ttaccagtga ttttggaaga gcgccaatga cgtctcccaa accacctgtt tttgaaaagg
     5641 gtgcaccctc tgctgctaca aataaaattt tcatgaatga atatcctctg ttactttagc
     5701 acctttctta accacaactg gatgttctgc agttcctcga atcacaacac caggctcaac
     5761 ttcaacccct ttgtccaaga tagcatattc gacctgagcc ccttctccaa taacaacacg
     5821 agggaagagc aggctatctt taaccaagct atccttatgg acatgaatat tacgtgatag
     5881 aacagaatta gctacttgac cttcaataat actaccagag gcaaactgag aagtgcttac
     5941 cttagatgta ttagcatagt aagttggctc ttcgtttttg acctttgtat aaatcttttg
     6001 gtttggtgag aaaagagaat agaatttttg tgattcaagc atatcgatat tcgcttgata
     6061 ataagattta acagagtgaa tattggctag atagcccgtg tactcgtagg cgaaagctcc
     6121 ctcttttaca gccaaatccc gtaaaacata gcgcaatttc tttggatgtt cttttttagc
     6181 ttcttcttcc aagtgttcaa tcaaccaagg tgtatcaacg acaaagatat ctgtagacat
     6241 attgaacgtt tcagctgttg acttgctatc aaagagttta tgagaaagaa catggtctgt
     6301 ttcatctaca tccaagattg catttacttc tgaaatatct ttcttagcta gttttttata
     6361 aactacagtg ataggctctt ttgttgtact atgtaggtgg aaaacttggt tcaaatcaat
     6421 gttaataaga acatcgcagt tgagggcaac cgtttggttt gagccagaac gtttcaaata
     6481 agtaagaagc tgttggtagt attcttttcc aactgtacta ctttctacac gggtattgta
     6541 aattcctaga tagtaatgac taagaagggt tgataagccc cactcgcgtc ctgaacgaat
     6601 atggtcaaat actgagctga tattatcctg ctggaaaata ccaaagacac tacgaacacc
     6661 tgcattagca aggcttgaaa gtgggaagtc aatcaaacga tatttcccac caaatggcaa
     6721 acttgctact ggacggtggt ccgtcaatgt cgacatattg tgaaaaccaa ctgtatttcc
     6781 taaaatggca gaatatttat caatcttcat ctgttgctac ccccactact tcattatatc
     6841 ctacaacttg tacttcatct gttccatcaa tttcgacacc gtcagaaata atcgcacctt
     6901 caccaataat ggcacgttta atcttagctc cttgaccaat gatagctcca ctcatgataa
     6961 ctgaatcaag gacttccgct ccttcgcgaa cttgcgcgcc tgttgaaagg atagaatgtt
     7021 taacagttcc atcaacgaaa catccgtcta caactaatga gtcttccaca tgagcatttg
     7081 ccccgaggaa gtttggtggt gaaatcaagt ttcttgagta aatcttccat tgacggttac
     7141 gactatccaa ggcattttct ggagaaatat actccatgtt cgcttcccaa agtgactcaa
     7201 tagtaccaac atctttccaa taaccactaa attcgtaagc ataaacactt tcacctgact
     7261 caaggtaatt tggaatgaca tttttcccaa agtctgacat gccaaccttg ctcttttcag
     7321 cagcgactaa catattacga aggcgttgcc aatcaaaaat gtagattccc atagaagctt
     7381 ttgtagattt aggttgagct ggtttttctt caaattcaac aatacgattg ttagcatctg
     7441 tgttcatgat accaaaacgg cttgcttctt taagagggac gtctaaaact gctactgtca
     7501 agctggcatt attatcctta tgagactgga gcatatcatc atagtccatt ttgtagatgt
     7561 gatccccaga caaaatcaag acatactcag gattgacact gtcgatatag tcgatatttt
     7621 ggtaaatagc gtgactagtc ccctcaaacc aacgatttcc ttcacttgca gaataaggtt
     7681 gaagaataga gacacctgaa ttgataccgt ctagtcccca gcttgaacca ttcccaatat
     7741 ggttgttgag agcaagtggt tgatactgtg taacgacccc aacattatga atccctgagt
     7801 tggcacagtt tgatagggca aagtcaatga tacggtagcg cccaccaaat tgcacagctg
     7861 gttttgcgat gctttgagtg agtttaccga gacgagttcc ttgcccacca gcaagaatca
     7921 aagctaacat ttcatttttc attttctact cctttttggt ttttatttgt gacggtttta
     7981 gtagatttca agcgacgttt gattttccat acacttgctc ccatagccgg tagagtaaag
     8041 gttaaggtct gctcataatc tttccatagt ccttcttgcg tttgaacagt ttgattatgt
     8101 tctttccaaa cgcctcccca ctcttccaac tcagtattcc atacttcttc gtaaattcct
     8161 gcaacgggta gtccgattgt aaaatctttc cgctcaacag gtaccatgtt aaagatacag
     8221 attaacattt ctcccttttt acccttacga ataaaggaaa gaacactctg gtctcgatta
     8281 tccgcatcaa tgatttcaat accatcatag ctggtatcga tttcccacag acagcgatga
     8341 tctttgtaaa actggtttag ctgagaagtg aaatacttca tcttagcatt cattgggtct
     8401 tctaggttag accattccaa ctgttcttca gatttccatt ctaggaattg accgtattcg
     8461 ctacccatga agagcaattt cttaccaggg tgacaaattt ggtacgtata gagattgcgc
     8521 aagcctgcga attgattgta acgatctccc cacatcttat gcatcatact cttcttgcca
     8581 tgaaccactt catcgtgcga gaatggcaag agataattct ccttgaaaac atacataaag
     8641 ctgaaagtca ccaggttaaa gtcatattta cgatagatcg gatcttcttc gtagaaacgg
     8701 aggatatcat tcatccagcc catgttccat ttgtagtcaa atcctagacc accaatctct
     8761 ttcattcccg taatcttggt cgcagacgaa ctttcttctg caatcatcat cacatttgga
     8821 tattctaact taataacctc attcaagcgc tgaaggaaat aataaccttc atagttgaga
     8881 tttccgccat ctttattagg tgtccatgga gcatcatcat agtccaaata gagcatgttg
     8941 ctaacagcat ccacacgaat accatccaaa tgatagacat caatccaatg cttaatgcaa
     9001 gaaattaaga aggactggac ttcatttttt ccaaggtcaa aattaagggc accccaacca
     9061 tggttatgag ccttattatg gtcttggtat tcaaaagtcg gtgtcccatc ataataggct
     9121 aaggcatcat cgttgatggt aaagtgacct ggtacccagt ccacaataac cccaatatta
     9181 tgggtatgac actcctcgac aaaatcttga aactcctctg gtcggccata agcatgctct
     9241 aaagcgaagt aacccataag ctgatacccc caactcaagc ccaaaggatg ggacatcaag
     9301 ggcataaact caatatgagt atagttcatt tcaacgagat aaggaatgag ttcatccttg
     9361 agctgggcaa aactataagg actgccatca gaatttcttt tccatgatcc agcgtgaact
     9421 tcataaatat tgacaggacg ctcttcaaag ccccaacgtt ttcttcgtgc cagccaaagt
     9481 ccatccttcc atttcttctc aggaagctct gttaagattg cccctgttcc tggacgagcc
     9541 tcatacctga cagcaaaagg gtcaatcttc atcagttgat gaccattttg acgtgtgaca
     9601 tgatatttgt aaatatgccc ttcttgagcc atattggtaa agacttccca gaccccaaaa
     9661 tcatttctta ccattggaat ctgattttca atccagttgg taaaatcacc aaccaagtga
     9721 acagcctgag cattaggtgc ccaaacacgg aaggtatagc catgctctcc atttagttct
     9781 tccctatgtg ctcctagata atgttggaga taaaaatttt cacccgtcat aaaggttttt
     9841 aatgcttctc tattatccat atactcccct tctcctgtaa gcgttttcta tgtttttatt
     9901 atactacctt tttagagaag attcaagtaa attactatac ttctttaatt attttgaaaa
     9961 tctacaacaa gttcacttac tcgttcaatt gtaaatcaat attttttcaa aaaattgcga
    10021 aaacgccttt ctttttctac tatagtgaaa tgaaataaaa catgcgcaaa tcgattaagg
    10081 actttaatct aatttctaa
//
LOCUS       DBERAE010000059         9438 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.59, whole genome shotgun sequence.
ACCESSION   DBERAE010000059 DBERAE010000000
VERSION     DBERAE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.59"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="ACL70N_001969"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="ACL70N_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS0590709.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /gene="gla"
                     /locus_tag="ACL70N_001970"
     CDS             complement(2499..3368)
                     /gene="gla"
                     /locus_tag="ACL70N_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGS0590710.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3592..4212)
                     /locus_tag="ACL70N_001971"
     CDS             complement(3592..4212)
                     /locus_tag="ACL70N_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS0590711.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKAPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEPTPEPGTPKTETPVNLDPEV
                     PTYETGKREGLSNTGTEANATLASAGIMTLLASLVLGFFKKKEDEK"
     gene            complement(4170..5276)
                     /locus_tag="ACL70N_001972"
     CDS             complement(4170..5276)
                     /locus_tag="ACL70N_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGS0590712.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5387..5641)
                     /locus_tag="ACL70N_001973"
     CDS             complement(5387..5641)
                     /locus_tag="ACL70N_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590713.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5635..5877)
                     /locus_tag="ACL70N_001974"
     CDS             complement(5635..5877)
                     /locus_tag="ACL70N_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590714.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(5999..6532)
                     /locus_tag="ACL70N_001975"
     CDS             complement(5999..6532)
                     /locus_tag="ACL70N_001975"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGS0590715.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6519..6845)
                     /locus_tag="ACL70N_001976"
     CDS             complement(6519..6845)
                     /locus_tag="ACL70N_001976"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS0590716.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7079..8797
                     /locus_tag="ACL70N_001977"
     CDS             7079..8797
                     /locus_tag="ACL70N_001977"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGS0590717.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKEIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8908..9255
                     /locus_tag="ACL70N_001978"
     CDS             8908..9255
                     /locus_tag="ACL70N_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS0590718.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
BASE COUNT         2716 a         1933 c         1769 g         3020 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgc
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggggga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttgggttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgg acttgtaagc gtttttattc ttcacgaaag acctcgttct caaaaccagg
     3541 aaaaaagccc acatctgtga gcttttcctg gttcctagat tctaaaatct attatttttc
     3601 atcttctttt ttcttgaaga atcctaatac tagactagct aacaaggtca tgataccagc
     3661 actagccaag gtagcattag cttctgtacc tgtgtttgac aatccctctc tcttacctgt
     3721 ctcataagtc ggaacttctg ggtctagatt cactggagtt tcagtttttg gagtacctgg
     3781 ttctggagtt ggctctggta ttggagtctc ttgatttggt agttctgggt ttggtgtcgg
     3841 aacacttgga tgctctggat ttggttgtgg gattggtttt tctggagttg gtttatctgg
     3901 tgttgataaa cggtcatacc ttaccgttat ttctttatca ctagagtctg acgtaacttc
     3961 ttgtgattca actgttggaa tatctggagc tttgtacttg tcaatcttac cagatacaac
     4021 ctcgtcccag tttcctgttg tccattcacc gtaggttaca actcccgtga ccttgttctc
     4081 agtttttgta cggcttaagg ttacaggttg aacaacatct tcttttacat tttggttcgt
     4141 aactttatca acgtaatgaa tgatacgcgt tatagtcttc gtctcagtag aggttgctgt
     4201 tttgggaacc actgtttcct caacattctc acggtagtaa tagtcaactg ttgcaccgtc
     4261 ttctggtacg catttgcagg agttgctacc aaggtgtatg ttgttttcct tgtgataact
     4321 cggtcttctt tgtcctcagt tgttgttttc ccttcaatag tttttgattc tgtggtatac
     4381 tcagaaccta tcgctaaatc agcttttata acagactctg ccaacttctc ttggctacct
     4441 tctttatagt aattggctgt tactgtagca gtggttggcg cttcgctttc tctataaact
     4501 aaggtcactg ttctaccttc gcttacaata ttcccagtta aacttgcaga atttgtatct
     4561 gcttctttaa aagtataata ttttccgtca gtagtagtca tgctactgag ttttttatct
     4621 gtgacattgt agctggtacc aatcagttgt tttttattgg taatgtaggt tccgtcactt
     4681 tctttttctc caattccagt atcatttttc aatgatagca aacgcccttg ttcatcaaca
     4741 tagcgaactt tcacattttc tgagattagt tctgccaatt ctgaggtttt tttctttttc
     4801 ttgatttctt cggttatttt ccctttctct tcttcgggaa tatttagttt tggaatgatt
     4861 ttttcaacaa cggttcgtga tggttccaca gtatcttgga tgactgaaaa gtcagctaga
     4921 attgggagat tatactgaac acggtgactt tgagtgttta ctcctactct ttcattattc
     4981 tctgaaaata cttgtacggt ataagaaaca acatcttttc ctaatagaac atccccagta
     5041 gagaaatagc cgccttttcc tagtttgcta tctccagagt ccacttcttt cctaatctta
     5101 tcagatagtt ttttaccagt cagtacattc gttcgcacaa tccctttgtc tacccctaca
     5161 aagtgggaga actttttgaa ctcttcagaa ccagatctag cccaaccatt attaagggca
     5221 tttgcttttg tatttgtatt ctctctcaaa ggtttggcga ttagaattat attcatcggc
     5281 acttagagtt gctgctatat ctgactcttg aataccaact tccttactac catttctagc
     5341 ggcagtatat gtgtatttat ctgtttctac ttctagctga ttatccttaa catgataggt
     5401 aattttctcc tggtataaga gtcttcagta gtttatatgc tctgtcatca tctttagctt
     5461 tagaagcagc tgagtttagc caagttgggg tattaggagt atctttatca gcctgtttca
     5521 agacattatt caagtcattt gctaacctat tggttgtcct cactgtgaaa gttttcttcc
     5581 agtctgaatc acttttatta gacttagata tgctcatgaa atcctggtca acattcaaca
     5641 caatatcgcc ttgtttttta gcatcttccg ttgcttctgc ttcaaattga tcatggagtt
     5701 tttgttgctc tggtgtatag tttttttatt tacacgattt aatgtactat tttttatttt
     5761 agtattaaga actccattaa tacgattttt aaattctgct tcaaaaaatc ccttaatttg
     5821 ttggtgcgca agttcaacat tcaaaccttt cttatacaag tcttcattct gatacaagtc
     5881 ttcattctga acgatttcgg ctacacggtg aatggtttga tcgtataccg tcttctctta
     5941 accagcagta tccttagttt taatgactac tcgataggtt cctttagaac cgttatagtc
     6001 atctagtttt aaaaaagcat tccaaacatt caaaaatagt tggaacttcc cttaataaat
     6061 ccgtcacttt ctttttcaag atagcccaag cttgctcaat aggattcaaa tccggtgaat
     6121 aaggtggtag aggtaagaaa aagtgtttat cttggatgca gagttcatcc aaaatgttct
     6181 tgggatgaaa actagcattg cccatgacaa taacatgagg tgtcttcaaa gcaggtagga
     6241 gttgcgtttt gaaccactcc acaaagaaat cgcttgtcat gcttttcttg taaatcatgg
     6301 gagctataaa ctctccgtct acttgtcctg caacaattga agttcgctca aaacgacgtc
     6361 cgctaatctt ttcatagact ttctcccctc taggagcccc tgcataagga cgatagaggt
     6421 agcggtcgat tcctgtttca tcaatatata cgattggtaa atcttttagg ttatccaaaa
     6481 tatcaagaaa ctcagcgact ttctctgact cttgttcctt aaagatcgtc atcttttttt
     6541 aaagtgacct taatctgctt taaagctgcc catactgaag gaacagcaca atcaaaatgt
     6601 gccgcaattt cccgtaaaaa agcatctgga tgagcctcta caaaggcttt caattcttct
     6661 aaagggatct tacgcttttt gacgactcgc tttttccgct ctaagttcct ttgttcacgt
     6721 ctttcttttc ccacgtgaag agagttctga cgccaacacc aaaaaacttt ggccgcctcg
     6781 acatgtctgt gccctccttt gatggaatct aatgctcctt gtttaaaatc agtattatat
     6841 gccatagctt tattagacca tgcttatttt aaactaagca actatatcaa tgttttgtta
     6901 tgagaagact tacttttttt actgaaattg aatttttcct agcctcaaca tcatataacc
     6961 ccaaaattca atctgacctg gtttgaagag atgttcgaag cagataaggt tttactaaaa
     7021 ctaaaaaaaa tgatataatc aaactgatta aatgttttaa aaataaagga gaatttgaat
     7081 gtcttaccaa gaaaattacc agaaatgggt tgattttgtg gagcttcctg actaccttcg
     7141 tcaagatttg gaaaatatgg acgaaaaaac taaggaagat gccttctata caaatcttga
     7201 atttggtact gcaggtatgc gtggcttggt tggtgctggt acaaaccgta tcaacatcta
     7261 cgttgttcgc caagctactg aaggattggc tcgtttgatt gagtcaaaag gtggaaacga
     7321 gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac ttctcacctg agtttgcctt
     7381 tgaatctgcg gcagttcttg ctaaacacgg catcaaatct tacgtatttg aaagccttcg
     7441 tccgactcca gaactatcat ttgcagttcg tcatctcaac tgtttcgcag gtatcatggt
     7501 cacagccagc cacaaccctg ctccatttaa cggttacaag gtttacggtg aagacggtgg
     7561 acaaatgcct ccacacgatg cggacgcttt gactacttat atccgtgcaa tcgaaaaccc
     7621 atttgcagtt gaagttgctg atgtggaaac tgaaaaagct tctggcttga ttgaagttat
     7681 cggcgaagct gttgacgtag aataccttaa agaggttaag gacgtaaaca tcaacccagc
     7741 cttgattgaa gaatttggta aagacatgaa gattgtctac acaccacttc atggtactgg
     7801 tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt gactctgttc aagttgttga
     7861 agcgcaagca actgctgacc cagacttctc aactgtaaca tctccaaacc cagaaagcca
     7921 agcagccttt gcccttgctg aagaacttgg tcgtcaagtt ggtgcagatg ttcttgtcgc
     7981 aactgaccca gacgctgacc gtgttggtgt tgaagttctt caaaaagatg gtagctacct
     8041 caacctttca ggtaaccaaa tcggtgctat catggctaaa tacatcttgg aagctcacaa
     8101 aaacgctgga actcttcctg aaaatgccgc tctctgcaaa tctatcgttt caactgactt
     8161 ggtaacgaag attgctgaaa gctacggcgc aactatgttc aacgtcttga caggtttcaa
     8221 atttatcgct gaaaaaatcc aagaattcga agaaaaacac aaccacactt acatgatggg
     8281 atttgaagaa agcttcggtt acttgattaa accatttgta cgtgataaag atgccatcca
     8341 agccgttctt gtcgttgctg aacttgctgc ctactaccgt tctcgtggtt tgacacttgc
     8401 tgacggtatc gaagaaatct ataaagaata tggctactac gcagaaaaaa caatctctgt
     8461 tactctttca ggtgtcgatg gtgctgaaca aatcaaagag attatggcta aattccgcaa
     8521 caatgctcca aaagaatgga acgcaacagc tatcactgtc gtagaagact tcaaggcaca
     8581 aactgctact gttgctgacg gtactgttac aaacttgaca actcctccaa gtgatgtgtt
     8641 gaaatacaca cttgctgacg gttcatggat tgccgttcgc ccttcaggta cagaaccaaa
     8701 aatcaagttc tacattgcag ttgtagggga aaccaacgaa gaatcacaag ctaagattgc
     8761 taacatcgaa gcagaaatca atgcatttgt aaaataaaga cctataaaag atgagaccaa
     8821 ccaacctcat cttttttcgt atcaaatcta agcaatttta gaaactttat ggcatactag
     8881 acttatcaat gaaagcgagg taatctcatg gaacaatttt tagataacat caaagacctt
     8941 gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata aaaaagaaac tgcaaccttc
     9001 tttatcggtc gcaaaacttg cccttactgc cgtaaatttg caggtacatt gtcaggtgtc
     9061 gtagctgaaa ccaaagctca catttacttc atcaatagtg aagaaccaag ccaactcaat
     9121 gatttgcaag cattccgctc acgttatgga atcccaactg taccaggttt tattcatatt
     9181 acagatggac aaatcaacgt ccgttgcgac tcttcaatgt cagcacaaga aatcaaagat
     9241 ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat cacaaaaacg cataatgtaa
     9301 ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa aacagttaca tcagtatttc
     9361 attacagaac attttaattt tggaagtcaa atcaattttt aacaatgttt tagaaatcac
     9421 agtgggctat tccatatt
//
LOCUS       DBERAE010000060         9172 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.60, whole genome shotgun sequence.
ACCESSION   DBERAE010000060 DBERAE010000000
VERSION     DBERAE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.60"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..743)
                     /locus_tag="ACL70N_001979"
     CDS             complement(<1..743)
                     /locus_tag="ACL70N_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGS0590719.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGFLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMT"
     gene            complement(758..1606)
                     /locus_tag="ACL70N_001980"
     CDS             complement(758..1606)
                     /locus_tag="ACL70N_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGS0590720.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1603..3078)
                     /locus_tag="ACL70N_001981"
     CDS             complement(1603..3078)
                     /locus_tag="ACL70N_001981"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGS0590721.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3401..4756)
                     /locus_tag="ACL70N_001982"
     CDS             complement(3401..4756)
                     /locus_tag="ACL70N_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0590722.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(4766..5083)
                     /locus_tag="ACL70N_001983"
     CDS             complement(4766..5083)
                     /locus_tag="ACL70N_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0590723.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5100..5417)
                     /locus_tag="ACL70N_001984"
     CDS             complement(5100..5417)
                     /locus_tag="ACL70N_001984"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590724.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5432..6328)
                     /locus_tag="ACL70N_001985"
     CDS             complement(5432..6328)
                     /locus_tag="ACL70N_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGS0590725.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6331..7593)
                     /locus_tag="ACL70N_001986"
     CDS             complement(6331..7593)
                     /locus_tag="ACL70N_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0590726.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDILLYLPFVIAIEKRFKLLED"
     gene            7873..9051
                     /locus_tag="ACL70N_001987"
     CDS             7873..9051
                     /locus_tag="ACL70N_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS0590727.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALFYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         3196 a         1951 c         1293 g         2732 t
ORIGIN      
        1 gtcattccca tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt
       61 aagacttttg atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact
      121 ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga
      181 gacaactggg aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata
      241 gaaaaaaaca ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta
      301 gaaatcaagc ccaatagaaa accacaaatc atatagaatc ctatcttatc aaattgataa
      361 gtttttttaa aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt
      421 tgaacaatgg atactagccg tactgataat tgagataaca aaacttgaaa aataagatga
      481 cctagaaacc ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc
      541 tctttacttt gtgaaaatct tttggttgtt gaaataatcg ccattataaa aacagagaaa
      601 ctagaataaa aagcaatatc actgaccgaa tggtatccaa aactatccat aagtggctta
      661 attataattc caccacccat gcctgatata gaacccaatc cactagctat tataatgatt
      721 agaaaataaa taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac
      781 ctagatggct actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat
      841 tacaataaga acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta
      901 tcccatattt tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg
      961 gattgcgaca ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta
     1021 aaaattcata gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa
     1081 atcttccttg ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag
     1141 gatattcaga ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag
     1201 acattccgct ccaattacag aaagccaatg catcttctaa agcaacatga actactggat
     1261 ggtcttctaa acccactaga ttactattct caccgtaggg atgtttccag caagcgttcg
     1321 gaacttgtaa ccaccacgga gccccagcag gatgaggata tccctccctt tctgcctctg
     1381 gaacgaacaa tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg
     1441 tttctttcac aaattgagca aattcttgat tcgtaactgg agtatccgca atggaaaaat
     1501 cctttacact aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat
     1561 ttgttcccat cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc
     1621 cgttttcgtt agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac
     1681 aacaaaacct tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac
     1741 aataggttgg tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat
     1801 atcaaataac tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa
     1861 gatatattga ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc
     1921 ctcgtactgt ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt
     1981 tcctcctgcc aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat
     2041 tgttccccta ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat
     2101 acttccctga taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg
     2161 atccgaaaca aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa
     2221 aaagcgacta atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct
     2281 tctttgatca tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc
     2341 taatacttcc caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat
     2401 atcaaaatag tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag
     2461 aaaaaaagga accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca
     2521 gtttgttgga tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc
     2581 cattccgtca tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata
     2641 gtcactagca taatcaaatt gacttccata agccttatca tactttctat caacatgtag
     2701 atacccatcg tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg
     2761 catcttacca atacactctg tttgataacc catatcttta aagacttttg gaagagtatt
     2821 agtaaaattc caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa
     2881 gccagtcaat aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc
     2941 aaaattataa cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt
     3001 actattcaag gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg
     3061 ctgttttgtc tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata
     3121 tctaccttta ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg
     3181 ttatgtttta tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat
     3241 tttctagtac tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct
     3301 ttgtctaata acaattttag tggagataag aaatcctaca cctaactcat cttacacgta
     3361 atctatttct attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat
     3421 atgccatttt cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata
     3481 agatgatggc acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta
     3541 cccaagtaac gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta
     3601 ccgttgccat gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa
     3661 ctggtaaacc ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt
     3721 tagcaacttt tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta
     3781 atcctccaaa ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt
     3841 cacctttttg gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga
     3901 tgggagccaa tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga
     3961 tcatcagaat aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct
     4021 tgtaaaccca atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg
     4081 ctactatata catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag
     4141 ggggaactga atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa
     4201 tagaggctaa aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc
     4261 ctggaatcac attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa
     4321 ttccttgtaa gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg
     4381 taactgtact tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg
     4441 tatcaacctt gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa
     4501 caattggtat acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt
     4561 tcgtaatact ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca
     4621 aagcaatgga acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa
     4681 ctaaaaactt ctgattccca actttcattg caattggaga aagtttttct tgcattttat
     4741 ccaacattgt attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca
     4801 cttctttcgc caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca
     4861 tcaagaggct aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag
     4921 ccttatgcgc ctgtaataag gcagcattcg catcagctaa tcttcgattg gctttagaga
     4981 aatccccttt ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat
     5041 acataattag ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct
     5101 tagtctaata aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct
     5161 gtcatcggaa taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct
     5221 agtaaatagc gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt
     5281 tcttctgctt caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct
     5341 gccttttgca tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata
     5401 attgttactt tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag
     5461 atactgtatg tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg
     5521 ccagtccccc atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc
     5581 taagtgcaat ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac
     5641 tcaatacaag accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat
     5701 gaaaggctgg aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca
     5761 attgctctgc gacagaaagc tctgccacag gctcattcac tcctgccccg tgcatcttac
     5821 ctgcaataat caaaccagaa aagttttcct tagcagtttg aacagcctta atgatttctc
     5881 gattgctaac tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct
     5941 ctattcgatt caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct
     6001 ctagcatctt tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa
     6061 gctggtgtaa gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct
     6121 caaaaacatc aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag
     6181 aattagttat atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc
     6241 taccttcact tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag
     6301 atggatttgc actaattaaa cgtttcattc tcaatcctcc aataacttaa atcgtttttc
     6361 aatagctatt acaaatggta aataaagtaa gatatccaaa acaatcaata caatttgtag
     6421 taatgaacca gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca
     6481 acctggatct gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag
     6541 taagttaaac attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg
     6601 aacgccaaac attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc
     6661 caaagttttt agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac
     6721 taaacctatg gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt
     6781 aaaaatattt ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc
     6841 taaccataac ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca
     6901 aaaactacta ttaaggaaaa ttaagataag aagaccaata acattatttc ctaaaagtcc
     6961 aagtggacct cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc
     7021 taaagttgca taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact
     7081 aaagctttta gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt
     7141 tataaaccat tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc
     7201 ttttgatgcc atgaaagcgg taggcattcc tgctccagcc tctcctctaa tgaaaggcgt
     7261 aactgtaata aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg
     7321 tctagccata aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact
     7381 atcaacaccc ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc
     7441 tggaatagga aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt
     7501 tagagtaata ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac
     7561 tggaagtaac ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat
     7621 tatcaaaagt tatcaattat ctttattttt tgacgtcaag ttgttatttg attatctttt
     7681 gttatttata ttttacaact ataagaaagc cttgtcaagg atttgtgtaa acatttgatt
     7741 attttttatt atcaatatat aataaaaaga gaccagtaag taatgaaaag cttaaaaaga
     7801 ttaacatcta catttatcca tagcaaaaaa tcataggatt ttaagaatct gacaactagg
     7861 aagaaaacta atatgacctt atctaagaaa caattacaac taagagctaa aatactggaa
     7921 acagtttaca cattaggtcc catttcacga attgaaatcg ctactaaaac aggaataaca
     7981 cctgcaacaa ctagcagtat cacaaatgat ctgattaaag aaaatattct cttagaactt
     8041 ggtgaagacg aacacgatac aagcgtaggg agaaaaaaaa tcctgctaga cattcaagct
     8101 aaacgatttt actacattgg ttgtgaacta tctgaaaaac atttcacttt tgctttagga
     8161 gataatctag gaaatatctt aaaggaagag aaagaaattg ttactaaaca gttaatccaa
     8221 gaaaagggaa atcaactcat taaccagaca ctaaagcaat tcttaaataa ctgctctgat
     8281 tatgaaatag aagcaattgg aatcgcgcta cctggtcgct atttagatga ttataaaata
     8341 acaacaaaca atcctttatg gcaacatatc gacttagaaa tgattcaatc ccactttgat
     8401 aagcctttgt ttttctctaa caatgttaac tgtatggcta taggtaaacg cctatttagt
     8461 cgccaacaga atgaccctaa ttttgcttat tttcattttg ctagaggtat gcactgttct
     8521 tatatctacg acggaaacat ttatgggaaa ggaaatctaa tgattggaga aatagggcat
     8581 acagttgttt catctgaggg agaagaatgt agctgcgggc gcaagggatg cttacaaact
     8641 tttgctggag aatcttggtt aatcaaaaaa tcaaaaattc tatatcatca atctccctat
     8701 tctctacttc ctagtttagt caaaaatgcc gatgatattg atatccaagt tattttaacc
     8761 gcttatcaat taggtgacac tggaataatc acacttatcc atcaagcctt attctatctt
     8821 agtcaaacca ttttaaatat cagtatgatg attgactctc aaaaaatcta cctacatagt
     8881 cctttactaa caaatcaaca catcatccaa aaactatata gtgaaatgaa ctacaaaccc
     8941 aaactgctct ataatcgcct acctgaagtc attattgaac cttacaatga ttttacagcc
     9001 gcacactcag ctattgcact ttgtttgtat catacaattc tacattctta attttctatt
     9061 acatttaata aataggctaa aaagagggag tatatcataa aaagcgaata aacctgtttt
     9121 ctgaaaatca gaattctgtt ttgttcgctt tctttatatt tggaattata ct
//
LOCUS       DBERAE010000061         8369 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.61, whole genome shotgun sequence.
ACCESSION   DBERAE010000061 DBERAE010000000
VERSION     DBERAE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8369
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.61"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(627..935)
                     /locus_tag="ACL70N_001988"
     CDS             complement(627..935)
                     /locus_tag="ACL70N_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0590728.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(932..1240)
                     /locus_tag="ACL70N_001989"
     CDS             complement(932..1240)
                     /locus_tag="ACL70N_001989"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590729.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1245..2540)
                     /locus_tag="ACL70N_001990"
     CDS             complement(1245..2540)
                     /locus_tag="ACL70N_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0590730.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLALVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2558..3967)
                     /locus_tag="ACL70N_001991"
     CDS             complement(2558..3967)
                     /locus_tag="ACL70N_001991"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS0590731.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4125..4853
                     /locus_tag="ACL70N_001992"
     CDS             4125..4853
                     /locus_tag="ACL70N_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0590732.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5312..5506
                     /locus_tag="ACL70N_001993"
     CDS             5312..5506
                     /locus_tag="ACL70N_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0590733.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5628..5794)
                     /locus_tag="ACL70N_001994"
                     /pseudo
     CDS             complement(5628..5794)
                     /locus_tag="ACL70N_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5872..7182)
                     /locus_tag="ACL70N_001995"
     CDS             complement(5872..7182)
                     /locus_tag="ACL70N_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGS0590734.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7419..8291
                     /gene="nadC"
                     /locus_tag="ACL70N_001996"
     CDS             7419..8291
                     /gene="nadC"
                     /locus_tag="ACL70N_001996"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGS0590735.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2604 a         1465 c         1587 g         2713 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaact agaaaacgag tgccattcag ctcaaaacac
      121 tgatttgaga ttgcagataa gactagcccc ctcattaaca gatttacgat aaaacgatga
      181 caaggtgtgt tgctttttga tttctaaaga gtataatgat agatctctat aaaataagtg
      241 cgaaggaaat gagcttttat agtcctttcg ttttaaaata ctatctcaga tattcttata
      301 tcgacaagaa gtttttgagt cattccctca tcatacatat taaataaata gtggctcatt
      361 caatttttca ctagaataat aagctagtat agtaaactga aataagatat aaacaaataa
      421 attggagctt aacatccatt tccagcaatt ttttagaaac tacagtggac tattctagat
      481 tcaacatatt ataaaaacta gagtaaaaga aaaggattgg atcttgtgta atgcaggatc
      541 caatcctttc aatcattttg tccaactttt ggaggttcct acaatgtagt cgtcattaat
      601 aaagacagat gggaatgaca gtgttcctat ttattttgat agagatcgat gaattcttta
      661 gatagcaact gaataatctc tgttgaagcc atttggtctt ctgcatgcat aaatagcaag
      721 gagaatccta ttttttctcc agtagcttct ttttgtatga gattagagtg aatcttgtgc
      781 gcttctacta aggagtcttc cgcttcttca actttaattt tcgcttcttt taaatttcct
      841 gccttagcta gttggatggc ttcaataaag gatgatttgg ctgctccact attggcaatg
      901 agctgaaaac agatatattc catttcttct gtcatcttat ttctcctatc catgcaagtg
      961 cttgttccag aacttttgct ccattcatca ttccgtaatc ccgcatatca atggtatcta
     1021 cagggatatt tcctgcaatt tctttcacag caagtaactc ataacgaatt tgtggcccaa
     1081 ttagaatgac atctgcttca tggatattct ttttagcttc tgtcattgat tttgcttgga
     1141 tagagatttc aatcccacgt tcagtcgcac tttgttgcat ttttttaaca agcatacttg
     1201 tcgacattcc cgcattacat actaataaaa tttgtttcat aatcttaacc ttccatttct
     1261 tgttcaacaa ctttgtcatt aactttgata aatggaatgt atagaagaac tccaagtgca
     1321 aagatgatga attgaactag aactgctctc acgtcccctg ctgttgctaa ccatgcattt
     1381 aagaatactg gtgtagtcca aggaacttgt ataaatgcag gactcatgaa tcctgtaact
     1441 gttgctaagt agctgattaa aataccaagg actggaactg tgataaatgg aatagctaat
     1501 gaaatgttat aaacgattgg gtaaccgaat aatactggtt cattgatatt gaagatacca
     1561 ggtccaaaag ataatttagc cacgttttta gagacagcat tgcgactcac taagaatgtt
     1621 gctattaata aacataatgt agatccacta ccacccatta aagcgaatgt ttgtatttgt
     1681 gataggttga tgatgtgtgg aatggcttgt ccattatttg ctgcagtgat gttttcagta
     1741 atgttaatta atagtaatgg ttctaggatg gcactgtaaa taactgcttg gtgaatacca
     1801 aatagccata acatatttcc taaagagtaa ataataatga ccccgattaa gcttgtacca
     1861 atatgacgaa ttggttcttg aataaagatt gtaatgattg agattaagtt cattccagtt
     1921 atattgaata ataatgctga aacaacccca aataaggaga tgacggtcat gactggaagt
     1981 aatacgctaa atgatctact aacagctggt ggaatatttt caccaaggtt catttgtaaa
     2041 gctttaacgt ttgataattc aatgaataat tctgttgcaa taatcgctac gataaccccg
     2101 gcgaacattg cgcctgtacc tgtgttgttg aatgaaagaa cacctgaaat gtttacagca
     2161 tcttttgctc cgtcaggaac tacagaaact gtatttggca tcatcacaat taaagaaact
     2221 aatgctagca ttgatgctgc taacgggttt tcgaaatctc tgtttttagc taagaaataa
     2281 ccaaccatta cagcaataat catacctgaa atacttaaag taccgtttgc aattgttatt
     2341 ccccaatatt ggaattttgt taatgtatcc ccttggaaaa tccacttaaa taccgtgttg
     2401 ttcaaaagaa cgattaaacc tgccaaaata tataatggca ttactgttac gaatgcatct
     2461 cttagggttt ttaaatgaat ttggttccct agtttaccag caaaggtggc aaattgatct
     2521 ataaattttg agtttttcat ctgaatatct cctctcttta ctcctcaatt tctacttcaa
     2581 aaccgttatt gtcacttact ttgcgatacc atcttcctga gctcttgatg gttctctttt
     2641 gcgtttctaa atcaacggag ataaatccgt aacgattctt atatgcatta ttccaagacc
     2701 agcaatcaaa tgcggtccaa gcgtggtatc caaaacagtg acttccctct tcaatggctt
     2761 tatgtagcca tcttaaatgt tcttcataaa attcaatacg atacacgtca tcgataactc
     2821 cattttcatc gataaaccgt gcttcgtttt caacacccat tccgttttca ctgataaacc
     2881 atggaatatt atcatattct tccttcacaa tcatagcaat atcataaatg gctttcggaa
     2941 aaatttccca accacgatat ggattcatgc gacgctccgg ccattcatac tctttgaagt
     3001 attggtctgg catccagggc gtctgatatt cctcaggatt tgcttgtgct tgaacacgtt
     3061 ttggatggta gtagtttact ccaagaaaat caaccgtatt tgatttcatc agttgaagct
     3121 ctttttcggt atgactccat aacacgccat ctctctctag ctgttttacc aatctttctg
     3181 ggaaagttcc tttaacagct ggattcaaga agactttgtt aaagaagtct tctgtaaatc
     3241 gacttgcttc taagtcttct ggagaattac ttcttggata agcaggtgtc aagtttaaaa
     3301 taatcccaat ctttccatca agtcctaatg agcgatatag ttgaatcact tttgcactag
     3361 caaggtttag attatagatg acttgtacgg cctcttttcc ctttcctttt agatttggat
     3421 aatggaaagc atataagtat cctgcttctg gaatgaccat tggctcattg aaagttgtcc
     3481 agtaatgaac cttatctcca aagcatgtga aagcagtctt ggcaaacttc acgaataact
     3541 ccactacatg tttgctttcc caaccaccgt atttttgaag aagttccact ggtaaatcaa
     3601 aatgatgtaa attcatcaca agatccatct ggttcttttt agcttcttca atgatggcat
     3661 tgtagaaagc aatacctttt ggatcaggct cacctgtctc taaattcttg atgagtcgac
     3721 tccattggat ggaagtgcgg aaagaattaa ctccaatttc cttcatcaag tggaaatctt
     3781 cggtgtaagt atgaaaaaag ttactggcta caagaggtcc gacattatcg aaaaaatctt
     3841 ctggatgcgt tttgaaccag tagtccatca cattttcatg tacttttcca tattgacctt
     3901 ctgtctgagg tccgctagaa gcagctcccc accaaaacag attaggaaat actaactttt
     3961 ttttcatgct caacctcctt tctattattc tatacataaa gtatagcata attttaaaat
     4021 ttgtctagac atttttaaaa attgttgata catgtcttgt gtttgcctca tttcttgaac
     4081 tttgttatac tactattaga atattataga gagaaccaga ttaaatgagt acaaaatatt
     4141 tatttattta caatgagatt cgtgaaaaga ttctttgtaa taaatatacc atgaacgaac
     4201 aattgcctga tgaaatgaca ttagctaaac agtttgcctg tagtcgaatg acgatcaaaa
     4261 aagctttaga cttgttagtt tctgagggct taatttttag aaaacgtggg cagggaacct
     4321 ttgttctctc tcgtggcagc tcaaaaagaa aattaatcgt tccagaaaga gatatccggg
     4381 gactgacaaa aatatctgaa gatgctcatt ctacaattga ctcgaggatt attcacttca
     4441 aattagaatt tgcaaatgaa tttttagcag aaaaactaca ggtcgctttg cagagtccag
     4501 tttataatat ttaccgtctg cgtattattg acggtaaacc ttatgttctg gaacaaactt
     4561 atatgagtac cgatgttatt ccaggtatta ctgaagatat tttacaaaaa tcgatttaca
     4621 attacattga aggaaagtta ggattgcata ttgccagtgc tacaaaaatc ttgcgagctt
     4681 cttctagttc agaaaatgag caacattact tgcagctcct tccaacggaa ccggtatttg
     4741 aagtagaaca agtggcttat ttggataacg gaactccgtt tgagtactcg attagtcgtc
     4801 atcgctatga tttatttgaa tttaattctt ttgcattacg acattcctcc taggagaaaa
     4861 tgtgaaaatg aagccaatct tttacagact ctagtttaag aaaaatttaa aacagggcaa
     4921 gaaggtccca tctatgctta aatggtttct cttttctaaa taagatagct ttaaaagagt
     4981 gatcgtttta tccatcatgt tgaaaaatat cttcgtatag cttatagagt aggtactgaa
     5041 attgttcacc tgatctactt cttatagtta tttagtttta aatagtgttt caaacattct
     5101 tacactgacg agaagttttt gagtcttttc ttgtaacaca tatagtatac tgaggttaga
     5161 atagtagact gtgacttcta aaaaattgct agaaatgaat ttcaatctcc caatttattt
     5221 gttcatatct tcttttaata tattaaataa attctgaatc ataatcattt aaaaaaattt
     5281 tattttttat ttttcattac gaataatata gatgaagggg aaagagtatg aaaacagaac
     5341 tgtttctttt gctattagtt caaaaggaga aaaaatgaaa gtagaaaata tttcgtatag
     5401 ggtggatcat cgtatattgt ttgataatat ttcttttgat acttcgagtt caggcgtgac
     5461 attaattact ggtaaaaatg gtacaggaaa gtcaacttta ctatagtaga ttgaaactag
     5521 aatagtacac atctacttct aaaatattgt tagaaatcga tttgactatc ctgatctatt
     5581 tgtcctgttc ttatttcatt tcactacatc tcaaattgag tatgacgaag tgcgctccca
     5641 tgtcctggga acgcactttc ttcatatttt tcatattctt gaatccatcg ataaagacta
     5701 ttgggatgaa tttttaaagt tgaactaatc atttttacag gatgaggttt acagcagaga
     5761 gtttgaaggc tttatcaaag gtttttcttg gcataatgac ttttcctcgt ttccacttaa
     5821 ttttgtgtct actttattat accaagtcca cccttaagtt agataataaa tctaacttaa
     5881 ggaagctaga aggatgagaa tccaggtggt caagagtccc aaacttaagc tgatggggac
     5941 acccagaata atttgctttt tgaaggcaag gccacgttcc tctatattgg gaagtgagag
     6001 ttgaatgaga gaaccagctg atgaaaaggg tgagatatta gtagatagag cgccaataac
     6061 ggtggctgtt gtgagtaagt gaatatcaat ctggggattt tgagcactga tgatagcaat
     6121 gatgggaaag agggctggag ctacaacgga tagggtggaa ctaaagagtg acatcactcc
     6181 ggctatcaca caaaagaaca gaggtaacca gaaatgagga atggatgttg tcatgaggtg
     6241 ccctatcagt gtgactaaac ctgacttgac cgctagagac attagtaagc tcatgccgca
     6301 gagcatgata attgtagccc agggaacctt agctaaaatg gcttcttgct tccctaattt
     6361 gagccttaag gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa atgttttttg
     6421 ataagtagct atccaggcga tgtttgggaa aatgagatgc aacaagggaa aaagccaaac
     6481 caaaaccatg ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc tgaggagtgg
     6541 tggttggtca atagtcaagg atgagtttgt ttttccctta ctatagtgac tgtaacagga
     6601 taataaaagc aagacgatga gtgggtagat aatgctgacg ataaagatat gattgccaag
     6661 tgaaaaagct tgctcttccc atcccatttg cttaaacagg ccttgaaaga caatgcctga
     6721 gctactggtt atcaaattag cccctcctga agctccccaa ttgacggctt gagctccaat
     6781 caaagggtgt ttgtccgctt tttgacagag ggtaatcgct agaggacagc aaacggccat
     6841 agtagtgaaa aatccagcac ctaaagcaga caaaagggtt gccatcaggt ataaaatcat
     6901 gtagagggcg ttagggtagg tgcgtgtgcg gtagagaatg tgttgagcca aaacatcaag
     6961 agtaccgtta gttattgcaa agttataaaa gagagagacg ctaaaaatgg taaaaaagag
     7021 tgaggttggc caaaaatgaa gaagttcttt ggggcttaat cccatgagag tggttgcgat
     7081 gaggtaagaa aaagcaatag ccagcaggcc aatattgatt ttggtgcggt aaccaattcc
     7141 aatggctaga gcaatggcgc taatcattat taaatgaatc attgaattgt cctttcagtt
     7201 agaatatgga aataggttgg caattttggc gctcaaaaga ccacctgttt cctattggta
     7261 cttgactatt atacacaaaa aaaatacaat tgtcttgaca attgtattga cacttgttag
     7321 aattaaaaat gaggtattca ggcttgtgat ttcctatgga agttaatagt gattgcctct
     7381 aatgcttaca agtgatatta aaaatagagg acttagtgat gtcaatcatt tcaactgatt
     7441 taaccccttt tcaaatagat gatacattga aagcagcctt gcgagaagat gttcattccg
     7501 aagattacag taccaatgcc atttttgatc atcatggcca agccaaggtg tcgctttttg
     7561 ccaaggaagc tggtgtttta gcggggctaa ccgtttttaa aagggttttt accctatttg
     7621 atgccgaggt gaccttccag aatcctcatc aatttaagga tggggatcgt ttgactagtg
     7681 gcgatttggt tttagaaatc ataggctcgg tgagaagtct cttaacatgt gaacgcgttg
     7741 ccttgaattt tttacaacat ttatcaggga ttgcttcgat gacagctgct tatgtagaag
     7801 ccttagacga tgattgcatt aaggtatttg atactcgaaa aactactcct aatttacgtc
     7861 tttttgagaa atatgccgtg agagttggcg gtggctataa tcatcgcttt aatttatcag
     7921 atgctatcat gctaaaagac aatcacattg cggcagtagg tagtgttcaa aaggcaattg
     7981 ctcaagcgcg tgcctatgct ccttttgtga aaatggtcga ggtggaagtg gaaagccttg
     8041 ctgctgccga agaagctgcg gcggcgggtg ctgatattat catgttggat aatatgtcat
     8101 tggaacagat tgaacaggcc attaccctaa ttgcaggacg ttctcggatt gaatgttctg
     8161 gaaatattga tatgaccact attagccgtt ttcgtggttt agcgattgat tacgtctcca
     8221 gtggtagttt aacccatagt gctaagagtc ttgatttttc catgaagggg ttaacctacc
     8281 ttgatgtcta agttgtaaaa taaactaact ttttaaagga tgtctttcct ctagaacgag
     8341 ttttatgtca gatagtttaa acgcctctt
//
LOCUS       DBERAE010000062         8311 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.62, whole genome shotgun sequence.
ACCESSION   DBERAE010000062 DBERAE010000000
VERSION     DBERAE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.62"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(93..227)
                     /locus_tag="ACL70N_001997"
     CDS             complement(93..227)
                     /locus_tag="ACL70N_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HGS0590736.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWEILPKQVLEEQQQEVFN
                     "
     gene            complement(296..565)
                     /gene="blpJ"
                     /locus_tag="ACL70N_001998"
     CDS             complement(296..565)
                     /gene="blpJ"
                     /locus_tag="ACL70N_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGS0590737.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGSGLTCLGGMVGDKLGLSW"
     gene            complement(1031..1228)
                     /gene="blpI"
                     /locus_tag="ACL70N_001999"
     CDS             complement(1031..1228)
                     /gene="blpI"
                     /locus_tag="ACL70N_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGS0590738.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1509..3662
                     /gene="blpA"
                     /locus_tag="ACL70N_002000"
     CDS             1509..3662
                     /gene="blpA"
                     /locus_tag="ACL70N_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HGS0590739.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3673..5034
                     /locus_tag="ACL70N_002001"
     CDS             3673..5034
                     /locus_tag="ACL70N_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGS0590740.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSIISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            5091..5246
                     /gene="blpC"
                     /locus_tag="ACL70N_002002"
     CDS             5091..5246
                     /gene="blpC"
                     /locus_tag="ACL70N_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGS0590741.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(5291..6631)
                     /locus_tag="ACL70N_002003"
     CDS             complement(5291..6631)
                     /locus_tag="ACL70N_002003"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0590742.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(6645..7382)
                     /locus_tag="ACL70N_002004"
     CDS             complement(6645..7382)
                     /locus_tag="ACL70N_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0590743.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7387..7725)
                     /locus_tag="ACL70N_002005"
     CDS             complement(7387..7725)
                     /locus_tag="ACL70N_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0590744.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8001..>8311
                     /locus_tag="ACL70N_002006"
     CDS             8001..>8311
                     /locus_tag="ACL70N_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS0590745.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     N"
BASE COUNT         2741 a         1755 c         1295 g         2520 t
ORIGIN      
        1 ccaccaacat gttgctgcat aggctacacc tccaagtata gctccacccg cagcaccagt
       61 tgctgcacct tgccatgttc ctgttttaat gcctagttga agacctcttg ctgctgctcc
      121 tccaacacct gctttggcaa aatctcccaa ttgcatccgc caccttcaac gcaagcaagc
      181 atttcagtat ccataacaga aaattgtgac atcatttttg tatccatgac aaatactcct
      241 tttttaaaaa actaaaataa atcagaatag aatcctcata attttactat aagtcttacc
      301 aacttagtcc caatttatca ccaaccatac ctcctaagca tgttaatcca ctcccaattg
      361 caccaatgtg tgctccaaca aatgcaccag caagtccagc tactcctaaa gtggccaaac
      421 ctgctccagt tccaccagtt ataattcccg tagtgactcc tgtaatcagt gcattttgac
      481 aatcagtgga gctatacccc ccttcaactt tcgcaagcat ttcagtatcc ataacctcta
      541 actgtgacaa catttttgta ttcatgatga atacctcctt tttattttca atttgttacc
      601 aaagtcttaa attcaataaa caaatagatt ttttatagta tctttttgat tttcttaaaa
      661 aagtatatac gtctactatc ttcttaaagg tagcagtacc tatttttagt ctaagatttc
      721 aataatcttg agtatctaaa atatcttaat ttcgttattc tccttgcaat aaaaagtttt
      781 actatactat ttattaactt gcagaaagca aaaaatatta gtaaataata gtttatagtt
      841 aagtttttta ttcctaccaa tccatcaact aagtaaagca tcaacgatta cataaacgat
      901 tgataatata attaaaattt tgctaactat cttattctca tcattcttag ataactttga
      961 tattttgtaa gtaagtaaat aagacagtaa attaatagcg ataataatac tatatttaag
     1021 aatcataatc ttacaaagag gacataattc ctgaacctac acaaataagt gttgctgctc
     1081 ccccagttat cggaccagtc gcagcagcta atagtactgc tccaatacaa ccaccgattg
     1141 cagatcctaa attgcctctt cctccactaa ctatttcgag ttcttcatta tccataacag
     1201 aaaattgttc catcattttt gtattcatga caaatactcc ttttttattt ttaatttttg
     1261 tcttgttgca actttgacaa gtttagtata tcattatttt ttaatttttt tcatccaaat
     1321 cttgaattgc catcgaaacg tcttgaatta gcttttttat ttcaagccac ctctaaatgt
     1381 ttaaaaaaaa taatttctaa tcactttttt accattcagg aagttttaat gactattcaa
     1441 catttcataa aatatgaact tagttttatg gcataatata cctatccact atatgaaagg
     1501 aattgccaat gacttcttat aaacgtacat ttgttcctca aatagatgcg agagactgtg
     1561 gtgtcgctgc cttagcctcg attgctaaat tctatggttc agatttttct ctagctcact
     1621 tgagagaact tgcaaagacc aataaagaag ggacgactgc tcttggcatt gtaaaagccg
     1681 ctgatgaaat gggctttgaa acaaggcctg ttcaagcaga taaaactctc tttgacatga
     1741 gtgatgtccc ctatccattt atcgttcacg ttaacaaaga aggaaaactc caacattact
     1801 atgttgtcta tcaaacaaag aaagactatc tggttattgg tgatcctgac ccttctgtaa
     1861 aaatcactaa aatgtcaaaa gaacgctttt tctctgaatg gactggagta gctatttttc
     1921 tagctcccaa acccagctat caaccccata aagataaaaa gaatggtcta ctaagcttcc
     1981 ttcctctgat tttcaaacaa aaatctctca ttgcttacat tgttctctca agcttattgg
     2041 tcactattat caatataggt ggttcttatt atctccaagg aatcttagat gaatacatcc
     2101 caaatcagat gaaatcaact ttaggaatca tctcagttgg tctggttatc acctatatcc
     2161 tccaacaagt catgagcttc tccagagatt atctcctaac cgttctgagc cagagattaa
     2221 gcattgatgt gattttatcc tatattcgcc atatttttga acttcccatg tctttctttg
     2281 cgacacgtcg tacaggagaa atcatttcac ggttcacaga tgctaactct attatagatg
     2341 ccttggcttc taccattctt tctcttttcc tggatgtttc tattctgatt cttgtagggg
     2401 gcgtcttact ggcacaaaac cctaatctct tccttctttc tcttatttct attcctatat
     2461 acatgttcat catcttttct tttatgaagc ctttcgaaaa aatgaaccat gatgtcatgc
     2521 aaagtaattc tatggttagc tctgccatta tcgaagatat caacgggatt gaaactataa
     2581 agtcgctcac gagtgaagaa aatcgctatc aaaatataga cagcgaattt gtagattatt
     2641 tggaaaaatc ctttaagctc agtaaatatt ctattttaca aacaagttta aagcagggaa
     2701 caaaattagt tctgaatatc cttatcctat ggtttggcgc tcaattagtc atgtcgagta
     2761 aaatttctat cggtcagctg attaccttta acacactttt ttcttacttt acaactccta
     2821 tggaaaatat tatcaacctc caaaccaaac tccaatctgc gaaggtcgct aataaccgtt
     2881 tgaacgaagt ctatctagtc gaatctgaat ttcaagttca agaaaaccct gttcattcac
     2941 attttttgat gggcgatatt gaatttgatg acctttctta taagtatggt tttggacgag
     3001 ataccttaac agatattaat ctcacgatta aacaaggaga taaggttagc ctagttggag
     3061 ttagtggttc tggtaaaaca actttagcca aaatgattgt caatttcttt gaaccctaca
     3121 aagggcatat ttccatcaat catcaggata ttaaaaacat tgataaaaaa gtcttgcgcc
     3181 gtcatattaa ttacctaccc caacaagcct atatctttaa tggctctatt ttggaaaact
     3241 taaccttggg cggtaatcat atgattagtc aagaagatat tctaaaagct tgtgaagtag
     3301 ctgaaatccg tcaagacatt gaaagaatgc ctatgggcta tcaaactcag ctctctgatg
     3361 gagctggtct atcaggagga cagaagcaac gaatcgctct cgctcgtgct cttttaacta
     3421 aatctcctgt tttaatacta gatgaagcta ctagcggtct tgatgtcttg actgagaaaa
     3481 aagttataga taatcttatg tccctaactg ataaaaccat tctctttgta gcccatcgtc
     3541 tcagtatagc cgaacgaacc aaccgtgtca ttgttcttga ccaggggaaa atcattgaag
     3601 ttggtagcca ccaagagtta atgcaggcgc aaggtttcta ccatcatcta ttcaataaat
     3661 aaggagaatg tcatgaatcc taatcttttt agaagcgtcg agttttatca gagacgttac
     3721 cataactatg cgacagtgtt aattatacct ctttcattac tatttacttt catcttgatt
     3781 ttctcccttg ttgccacaaa agaaattact gtcacttccc aaggagaaat cgcccctaca
     3841 agtatcattt catctattca gtcaaccagt gataatccta tccttgctaa tcatttagtg
     3901 gcaaatcaag tagttgaaaa aggggactta ctcatcaaat actctgaaac aatggaagaa
     3961 agtcagaaaa ctgccttagc aactcaatta caaagacttg agaagcaaaa agaaggactt
     4021 ggaattttga aacaaagctt agaaaaagcg actgatcttt tttctggcga ggatgaattt
     4081 ggctaccata atacctttat gaattttact aaacaatccc atgatattga actgggtatc
     4141 acaaagacta acactgaggt ttcaaatcaa gctaatcttg ccaatagcag ttcatcagct
     4201 attgaacaag aaattacaaa agttcaacaa caaattggag aatatcaaga gctgagagat
     4261 gctatcataa ataacagagc acgcttacca actagcaatc cacaccagtc aattttgaat
     4321 cgttatcttg tagcctcaca aggacaaaca caaggaacgg cagaggagcc atttttatct
     4381 caaattaatc aaagtattgc aggtcttgaa tcatctatcg caagcctcaa aattcagcaa
     4441 gctggtatcg gaagtgtagc aacttatgat aatagtttag caaccaaaat tgaagtactc
     4501 cgcactcaat ttttacaaac agcttctcag caacaactaa ccgtggagaa ccaattaaca
     4561 gaattaaaag tacaactaga tcaagcgaca cagcgcttag aaaacaatac cttaaccgct
     4621 ccaagtaaag gtatcgttca tctgaacagc gaatttgaag gtaaaaatag aattccaact
     4681 ggtacagaaa ttgctcaaat attccctatc atcacagata caagagaagt actaatcact
     4741 tactacgtag cttctgacta tctacctcta ctagataaag gacaaactgt aagattaaaa
     4801 ctggagaaga ttggaaatca cggcattacc atcatcggcc aacttcagac aattgatcaa
     4861 actcctacca gaacagagca aggcaatctc tttaaattaa ccgctcttgc aaaactatct
     4921 aatgaggata gtaaactcat ccaatatggc ttacaaggtc gcgtcactag tgtaactgca
     4981 aagaaaacat attttgatta tttcaaagat aaaattttaa cccattctga ttaattttca
     5041 gataacactc tataactatt tattatctta tcaaaaagga gaatcataac atggataaga
     5101 aacaaaactt aacttcattt caagaactaa caactaccga actcaaccaa attacaggtg
     5161 gaggactgtg ggaagatatc ttatacagcc ttaatataat taagcataac aatacgaaag
     5221 gacttcatca tccaatacaa ctataaaaaa taagaccgag taacaagaac tctcggtctt
     5281 atttttttca tcattctgta ggtatcatag taagcacctg acgaaagact tgatcttgac
     5341 aggtagtatt taaactggca ttgggataac tttccacaat cttcataacg gtatagagac
     5401 cgacacctct ctcctcccct ttagaactaa ctccaaagga gaagatttca gaaatatcga
     5461 tgccctcttc tttgatggag ttttcaatga taaaagtctc ctgtgctcca ctttttaaaa
     5521 aggcaattga aacatgaggt tgaccggcct ctgcactcgc ttcaatagca ttatcacaaa
     5581 ggatagacac aatggttaga aaatcaagca gtctcatccc ctcaacctga atctcttcag
     5641 gaacttcgac attaaagaca atgtcctttt ctctagcttt tataaatttt ccagctagga
     5701 gacttttgag ggcacgatcc cgaacattca ccaatctgcc caggtcatat ttattgtcct
     5761 gcaatttctg actggaatcc cttaagacca agtcatagac ctcttttatc tgctccatat
     5821 cctcctcttc aatacccaga cgtaaacttg tcaagaggtt ggtgtagtca tggcgaaaac
     5881 tccttacttc cttgtaaagt tcctctatat gccgactata gcgttctata tctctatagc
     5941 gcaagacctg ctcttggtcc agtctatcat ggagtttgtc cttcaaatag gtatccaatt
     6001 tcttgataac ccccataaaa aataggaggt aaaacactag aatgagatgg cgaacagtcg
     6061 ttgattgaat accttgctca tattcaaagt aagacagact ttgtatcacc aaatagtaag
     6121 cccccattat ccagttaatc ttagtcaggg acttttgaaa acctgtatct agaatctccc
     6181 ttctcaaact agtaaaatca tagtccaacc atttcaaaaa ggctagagaa atgaagaaat
     6241 tgaaaattat tatacataac ccagtaaatg agtagccatc atatacttgc tcttgtccca
     6301 aaaatggaag cacaaaatag gagactcctc tataaaagag attcaccaat atcattggaa
     6361 agagaccata aaagaaaagg agttttttag gaagccctct taacaataag aaagacaagc
     6421 ctatgccgta caagggttcc ataaaataag ataggtaaac atttcctacc atatagccaa
     6481 tcattacaaa aacaaaggcc aacagtatct tcaaaagaaa ggccttaaaa atcctctcaa
     6541 aagtgagacc aattccatct accttaaaga aaatgacaat ttttaatccg tgagtaacaa
     6601 gtgtatacaa caatatccaa gcaacattca taaactctcc tagctcagtg taagttatta
     6661 atagcctcag acacttccct gaccttataa cgcgcgatca gacagcttcc accattggga
     6721 aagaaaagga gtttttcttt cttatccaaa tgcaccacat ttgcaggatt gatgagaaaa
     6781 gagcgatggc actgcaagag acggggttcc tgcttaaaaa cctcctctaa actcgccgta
     6841 aattctagcc tgtccgtctt ggtatagaga ataacacgat ggggtcttgg ggatgtttcg
     6901 agatagtaaa cctctttgaa aggatattgg aattgggcaa attttgattt aaagtaaaag
     6961 caatcttccg ccagactttt actatcttga ctattggcat agaggagggc tgtctcgata
     7021 cgagattcaa actcctctgc cgaaagggcc ttatcaatgt agtccaaagc tgacacttgg
     7081 tagcgaaagg acagaggcat aaactccgag tgagtcgtca caaagacgat tagggcataa
     7141 gggtcttgtt cccgaatctt tctagctact tccagtccct tcatctcttc atttcgaatc
     7201 tcaatatcca aaaagaatag ctgatgggcc cccttctcat gcacctctgc cagcagttgg
     7261 tccggcttgc caaatacctc aaaagagcta ggaatgatat gatgtgcttt caaaagtttc
     7321 tcaatcgtcg tttcaattct agtctgttgg gaaaaatcat cttctaaaac aaatattctc
     7381 atcttcttac tctccctctt tcaaccattt ttgacgtatt tctctatagc gacgtctggc
     7441 atacttgaca gcatattgac cttcttctcc gagaaaaagg attctttctt gaaaatcaat
     7501 cgattttaat ttatcaagat taaccaaaca atttcgatga catctcatca aagtttcccc
     7561 acattggttc tcaagattac ttaaattttg aagcatatta aaactagctt tttctgtaac
     7621 aatctgtacg gtatgggctt tagttggatg tgtttggata tagtagatat cgtcgatgtt
     7681 tactttatag actgttttct gtgtctgaat aatcatatgt ttcattggat tctcctccta
     7741 agaaaagaat aacagaaaag gtctagccca agcacaccca atcctaaaca gtctttgaaa
     7801 actcctaaaa ggattatttt ctacaacatc atgatgagct tacaactatt ttatcataaa
     7861 attcactcag cgcaattcaa gacatttcaa tgacaattaa agatttgaat aaaaaaaaag
     7921 aattaaaagt gataaactaa cagtatcaaa acacagttgc cagaagtaag actggcaccc
     7981 agattaaagg aggcattccc atgacagata cagaccccat caaaagagct catactttga
     8041 ttactgactt aaacaaagcc taccaagcat gcaaacaggc aagcgctgac gacgtccgct
     8101 ttcaggagca attaaactct attcttggtt ttctagccaa ggctgaaaca gtggataatc
     8161 gattcttgat tgaactagaa aaattttacc agacttccag tcttctcatg ggactcagcg
     8221 ctcttgatcc agatgctcca actcgcgccg cttggcgggc ctatgaccgc ttccactttg
     8281 accaagtcaa gaccaagtta atactcaatg a
//
LOCUS       DBERAE010000063         8179 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.63, whole genome shotgun sequence.
ACCESSION   DBERAE010000063 DBERAE010000000
VERSION     DBERAE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.63"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(52..1464)
                     /gene="sufB"
                     /locus_tag="ACL70N_002007"
     CDS             complement(52..1464)
                     /gene="sufB"
                     /locus_tag="ACL70N_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGS0590746.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVICELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(1518..1958)
                     /gene="sufU"
                     /locus_tag="ACL70N_002008"
     CDS             complement(1518..1958)
                     /gene="sufU"
                     /locus_tag="ACL70N_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGS0590747.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(1945..3171)
                     /locus_tag="ACL70N_002009"
     CDS             complement(1945..3171)
                     /locus_tag="ACL70N_002009"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGS0590748.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPAIARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(3182..4444)
                     /gene="sufD"
                     /locus_tag="ACL70N_002010"
     CDS             complement(3182..4444)
                     /gene="sufD"
                     /locus_tag="ACL70N_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGS0590749.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(4472..5242)
                     /gene="sufC"
                     /locus_tag="ACL70N_002011"
     CDS             complement(4472..5242)
                     /gene="sufC"
                     /locus_tag="ACL70N_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGS0590750.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(5392..5586)
                     /locus_tag="ACL70N_002012"
     CDS             complement(5392..5586)
                     /locus_tag="ACL70N_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGS0590751.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(5614..7269)
                     /gene="dnaX"
                     /locus_tag="ACL70N_002013"
     CDS             complement(5614..7269)
                     /gene="dnaX"
                     /locus_tag="ACL70N_002013"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGS0590752.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(7269..7766)
                     /locus_tag="ACL70N_002014"
     CDS             complement(7269..7766)
                     /locus_tag="ACL70N_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGS0590753.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            7960..>8179
                     /locus_tag="ACL70N_002015"
     CDS             7960..>8179
                     /locus_tag="ACL70N_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS0590754.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRI"
BASE COUNT         2378 a         1850 c         1520 g         2431 t
ORIGIN      
        1 ggcgatgctg acgtggtttg aagagatttt cgaagagcat aaaatcaaat tttatccaac
       61 tgatccctcc atttcatagc taatcaagcg gttcagctca actgcgtatt ccattggaag
      121 ttcttttgta aagggttcta caaatcccat gacaatcatt tcagttgcct cagattctga
      181 caatccacgg ctcatgagat aatacaattg ctcttctgaa atcttagata ctttggcttc
      241 gtgttccaaa gccacttgcg agttgtgaat ttcattaaat ggaatagtat ctgatgctga
      301 caagtcatcc atgataatgg tatcacattc aatgtgggaa acagatttct tagagttctt
      361 gttaaaggtg acttgtccac ggtagtcaac ctttcctcca cctttagcga tggatttaga
      421 cacaatagac gagctggtat gtggagcatt gtgaatcatc ttagcacccg tgtcttggtg
      481 ttgccctgca ttagcaaagg cgatagagag catggtacca cgcgctcctt ctccatcaag
      541 gtaaacagat ggatatttca tagtcgtttt ggcacccaag tttccatcaa tccactcaac
      601 agtggcatcc ttttgagcct tagcacgctt tgttaccaag ttatagacgt tatcagacca
      661 gttttggata gttgtataac gcatataagc tccgtccaaa gcaaaaattt ctacaatggc
      721 agcgtgtaag ctattgcttg aatatgttgg tgctgtacat ccttctacgt agtggacgct
      781 tgctccctca tcaacgataa tcaaggtacg ttcgaactga cctatatttt cgttattgat
      841 acggaaataa gtttgaagtg gaatatctac cttgacacct tttggcacgt agataaaagt
      901 tccacccgac catactgctg agttgagggc tgccaacttg ttatctgtcg gcggtaccaa
      961 cttcgcaaag tattgtttaa ataagtctgg gtattccttg agtgcggaat ctgtatctgt
     1021 aaagataata cctaattttt ggaactcttc cttcatgttg tggtaaacca cttctgactc
     1081 gtactgggca gaagcccctg ctaaataagc acgttcagct tctggaatcc cgatacgttc
     1141 aaaggtttct ttaatctttt caggtacatc atcccaagaa cgggctggtt tgtcagatgg
     1201 tttttggtag tagattaagt catcaaagtc aatctctgac aagtctgctc cccaagtttg
     1261 catgggcatt tttttgaagg tttcataaga cttcaaacgg aactccaaca tccactcagg
     1321 ctcaccctta gcagcagata attcacaaat aacaccttcg ttgagtcctt ttcctgtcga
     1381 taagacaggc tctacatcgt catggaaacc aaatttatat tcaccaaggt caattggttt
     1441 tggttctact ctttcttcag ccataatatc ctttctttct tcatttctaa taattcataa
     1501 gacaaaagaa acttgtctta ctgtttttct tgattttcaa ttgttttctt aagggcattc
     1561 caagctaggg ttgcacactt gattctttga gggaatttgg caacacctga caagaatgcc
     1621 gcgtctccaa gttggtcttg acgctcatct ttttgccctt gaaccatttc agaaaaaata
     1681 gtcgccagtt ctaaaatttc ttgtttggtt tttcctaaaa cggcatctgt catcatacta
     1741 gcagaagcag ttgaaatcgt gcatcctgaa tttagaaaag caatatcttc caaacggtcc
     1801 tctgcatcaa acttgacaga gaggttgatg acatccccac aagtcggatt gttgagactg
     1861 atttgctcag cgtcttctaa cttcccttgg tgatgtggat ttttcgaatg gtctgctacc
     1921 actgccatat aaaggctatc tagtttagaa agtgccattg aaaaactcct ttgtcttttg
     1981 tagggcatcg actagtttgt cgcaatctgc cttggtattg tagatataaa aacttgcacg
     2041 agctattgct gggacttcca aatactgaag caagggttgc gcacaatggt gaccagcacg
     2101 aacagccact ccttcataat ccagagccgt cgcaagatcg tgaggatgga gatcacctag
     2161 gttaaaggca ataacacccg aacgttgagc caaatcctga gaaccgtaaa tggtcaatcc
     2221 ctcaattgcc tgcagttttg gatagacgta cgcaatcaat tcctgttcat gagcttcaat
     2281 ggcatccata ccaatctttt ccagataatc aactgcagtc gcaagtccaa tagctcctgc
     2341 catatttggc gttccagcct caaatttcca aggcaattcc ttccaactag cagattgctc
     2401 gtagacaaaa tcaatcatct cgccgccaaa ttctactgga gacatttgct caagatactt
     2461 ttctttgccg taaaggacac cgataccagt cggaccagcc atcttgtgac ccgaaaaggc
     2521 gaaaaagtcc agatccaagt cctggacatc aatcttcata tgaggtgtag attgagcacc
     2581 atccactacc atgattgccc caacttggtg ggctaattga gtgatttcct tgatcggatt
     2641 gaccacacca agaacattgg aggcatgagc tagggaaaca aatttaacct tatcagtcaa
     2701 tttagctcgc aaatcctcca tatccaaggc accgtcttta agatagacat agacaagctc
     2761 tgctccagtc tttcgacaag cttcctgcca tggaatgata ttagaatggt gttccattac
     2821 tgaaatcaag acctggtctc cctcagtgag aatttcctca gcaaagcgtg ccacccagtt
     2881 aaggctggtt gtcgttcctc tggtaaagag aacttccttt gtagagcctg cattaataaa
     2941 cttacgaatg gtttcacgag cagcttcata agaagctgtc gctcgttccg ctaaggtatg
     3001 gacaccacgg tgaacattgg cattgtcctg ctcatagtag ctgttaatag ctttcagaac
     3061 tactagtggt ttttgtgtcg tcgcagcatt gtccagatag accagaggtt catcattgac
     3121 aatctgatct aaaattggaa aatccttgcg aatcgcttct acatctaaca taggctgccc
     3181 cttagcgttt tgacaatttc tcttcgatag ttgcaatcat ttcatcacga acttccttga
     3241 ctggaatctc cacgataaca gatccaagga aaccacgaac aaccaaacgc tctgcagttg
     3301 ccttatccaa tccacgactc atgaggtaat acatgtcttc tggatcaact tgtccgatag
     3361 acgctgcgtg tcctgcagtg acatcatttt catcaatcaa aagaattggg ttagcatctg
     3421 aacgcgcttg gtctgaaagc atgagaacac ggctctcttg ttgggcatct gctcccttag
     3481 cacccttgat gatgtggccg ataccattga aagtcaaagt tgctttttca aggataaccc
     3541 catgttgtag gatatttccg atagagttgc agccatagtt agttacacga gtatcaatcc
     3601 cttgtacctg acgaccactt gaaagagcta caaccttgag gtcagcatgg ctaccattac
     3661 caatcaagtc actatcaaaa tcagcaacga catttccttc gttcatgaca ccgatagccc
     3721 agtcaatact tgcatcgttg cctaatttac cacgacggct aatgtaggca gtgacgtttt
     3781 cacctagtcg gtcgatagca gcaaacttga cttgcgcacc tgaacgtgca atcacttcta
     3841 ctgtgatatt agcagttgct ttggcacttc cttcaccgcg tgactctaaa cgctccagat
     3901 aattaatctt agaattttta ccagcgataa tcataatatg cttgttaaac ggcacattgc
     3961 tatcgctatc ttggtagaaa attccttcaa ttggctctgt gatttctacg ttatctggaa
     4021 tatagagtac agcaccactg ttaaagtaag ctgtgtggta agccgccaac ttgtcatcat
     4081 catacttaac agatgacatg aagaattctt cgatcagctc tggaatttct tctaaagctg
     4141 agtgaaagtc tgtgaagaca acaccctgtt cagctaactc aactggagtt tgttcgaaaa
     4201 cagtttgagt tcctacttgc accaacttca agtgatgatc taaagctgtg aaatctggaa
     4261 catttgctga tggctcattt tctgtaatcg ttccatcacc cagattccaa cggtggaatt
     4321 tgacacgctc aataactggt aattccaaag tctcaatctt gtcaaaagct ttttgacgga
     4381 gatcagccaa ccagcttggt tcagcgtgca tttctgaaaa aagtttaata ttttctctag
     4441 tcatttactt ctcctaaaag atacgaggga attacaattc ttccttgtag tcgtagccaa
     4501 gttcttcagc taattttgcg tatccttcac gttccaaacg cgcagccaat tctggaccac
     4561 cagaaaggac aacacgacct tccatcatca cgtgtaccac atcaggtgtg atatagttca
     4621 aaagacgttg gtagtgagtg atgatcatag caccaaaacc ttcaccacgc atggcattga
     4681 cacctttaga cacaacttta agagcgtcaa tatcaagacc tgagtcaatc tcgtccaaaa
     4741 gagcaaatgt tggctccaac atcaaaagtt gaagaatttc attgcgtttt ttctcaccac
     4801 cagagaagcc ttcgttgagg taacgctctg ccatttcttc tttcatgtta agcaattcca
     4861 ttttttcatc tagcttagta ataaactcac gaactgaaat cttctcatca tcttctttac
     4921 ccgcattcat agcggcacga agaaattcag cattggtaat tccagggatt tctgatgggt
     4981 attgcatagc aaggaaaagt cccatacgcg cacgctcatc cacttccaac tcaaggatgt
     5041 ttacgccatc aaacaaaact tcacctttag ttacttcata gtttggattt cccatgatag
     5101 cggcagaaag agtcgattta cctgtaccat ttggtcccat gatagcggca atttctcctg
     5161 ttttcagggt caggttaacc ccttttaaaa tttcttttcc ttcaatctca acgtgaagat
     5221 ctttgatctc tattactgac atgatagttc ctttcttttt caaaactttt acagtactta
     5281 ctagaaaaac gtctgatttc cccagaaata gagcaaaaat tctataaata tacttttcta
     5341 gtataacaaa aaaaagccta aaaggctttg attttgtctg gaagctgagg gctagtcttt
     5401 cctattaaaa tgctgatcga tgacatcaac gattttaccc atcacataac tgactcggaa
     5461 atttctaaag agtaaaattg cccaaaaggc tgccataata tagcggccag tcatccaggc
     5521 ttcattgaaa aaataggtct cagcagctgt aaatagcgcc ataataataa attgttgttt
     5581 attcataaac ttattgtatc atgaaatctt tctttagtct tcctctacct tcactttatc
     5641 agccaaaaat tcaaatcctt ctggaatcag gctttcttct acttcttttt cagtttgaga
     5701 agatttggct ttggctgaaa aggctgcgcg aacttctttc cattcctcca tggaaatagc
     5761 taaaatctca ggtgaaaaac ctgccgcctg actgaggata ttaccaaaca tggtattgag
     5821 attgtctcgt ttcatagttt gaccagcatt gaagttagac tcaaaagcaa gaatagcatg
     5881 gtgttcattg gcagcaaccg gttgagaacc agctagcaga gccttgtccg gcccacctag
     5941 actttcaatt acctctcccc aggcattctg caaacgaatt aaattttgac gtgctaaatc
     6001 aggattttcg acggcctctt gtaagataga ttgcacttta ttgcgatcga cacgatagac
     6061 tgttttgccc gtagctggtc gactaggagc tggtgcaact tgtttaggaa ccgcacctgc
     6121 attagaaagc tcttgtttga gacgggcaac ttcctgtctc agcgtagcaa tttcattttc
     6181 aaccgctcct gatagagctg gttcgggctt gatttccgcc aaacggacgg tcatcatttc
     6241 agcataaatc ttgggctgca aactagactt aatatctgct aaattcactg ttgctaagcg
     6301 aatcatttca aacagatttt tttgaggaag tgccaaattt tctacaaaga ctgaactatg
     6361 atgagtattt tctccccctg tttgaacaat taacaagtct cttaaatagt gcaaaagatc
     6421 ggtcacaaaa cgagtcatgc tcttaccatt gtcaaaaaga agattcaagc aagacaaagc
     6481 tttgggaaca tcctgttgag acaaggccgc cacataatca tccaaggctg ataggctaat
     6541 ggtgccagta atttcttcag agatagcagt cgtcagctca tttccctgtg tcaaactcag
     6601 ggcttgatcc aaaatagaca aggcgtcccg cattccacct tccgcccgtc tggcaatgat
     6661 ttccacagcc tctggttcag aactgatatt ttctttttct aagatatagt gaatatgttc
     6721 cttaatatcc tgtgtcttaa ttgatttaaa ctcaaaacgt tgcacacggg atagaatagt
     6781 agcaggaatc ttgtgcaatt cagtagtggc caaaataaag actacattct gtgttggttc
     6841 ttccaacgtc tttaggaggg cattaaaagc ccctgtagac agcatgtgaa cctcatctat
     6901 gatataaacc ttataacgag caaggctagg cgcataggta gatttatcac gaatttcgcg
     6961 aatttcatct accccattat tagaagctgc atccatttca atgacatctt ctaaactacc
     7021 gtccgtcact gcttgacaaa tatagcagtt attgcaaggt tcgccaccca cttgattggg
     7081 acagttcata gccttggcaa agattttagc aacactggtt tttcccgttc cacgaggacc
     7141 agaaaaaaga taagcgtgac ttattttctc ttgctccacc gcttgtttaa gagtcttagc
     7201 cacaacttct tgaccaacta actgggagaa gttttgactt ctatattttc gataaagtgc
     7261 ttgatacatt aagatttttc ctcaaacatc gtaaagtccc atgttgtctt ttcaagcaaa
     7321 atagcgacaa attgttccaa ataatctcga tccatagcat cgtaatcctc aatctctgaa
     7381 gaatccagat ccagaactcc aagtaactga ccattcttca tcatcggcac cacaatttca
     7441 cttttagcta gactatcaca agaaatatag ttgagatagg tcgtcacatc tccaacaata
     7501 acagtttcct gaaagtgagc tgcctcacca caaaccccct tgcctagtgc aatacggatg
     7561 caggaaacac ctccttggaa ggggcctaaa accaattcct ttccatcgaa caaataaaag
     7621 cctgcaaata cggtattagg aaaacgtgat tttatgagag cactggcgtt ggaaagatta
     7681 gccaaaacat tggtttcgcc ttccaatagg aaggacaatt cttcatttaa catttgataa
     7741 cgtgattgtt tttctgattt taacatagaa ctattatatc aaaaaaggag cagagacaaa
     7801 agaaaaatcc cttgtttagt aaacaaagga ttttggactc tataatattt gtagtgggta
     7861 aatccactat agatattatg gagcctattt ttgtgtagaa aaaaagtccc atatgaccta
     7921 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
     7981 acaaaattac tagacattaa agaccctaat atccagattt tagacatcat caataaagat
     8041 acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc tgattgtgga
     8101 agtctaatga agaaatatga ctttcaaaaa ccgtctaaga tcccttacct cgaaacaact
     8161 ggtatgcctt ctagaattc
//
LOCUS       DBERAE010000064         7086 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.64, whole genome shotgun sequence.
ACCESSION   DBERAE010000064 DBERAE010000000
VERSION     DBERAE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.64"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            225..6659
                     /locus_tag="ACL70N_002016"
     CDS             225..6659
                     /locus_tag="ACL70N_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS0590755.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKGLSNLKNTKVLYT
                     YDRIFNGSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVI
                     SREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADQADEK
                     GMISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEG
                     EASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKRNIIA
                     YDDGSALQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2796 a          959 c         1361 g         1970 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttttgactt
       61 aaattttttt aaatgatata ctgtttttat agagagataa caattatata taaatgtact
      121 actctatttc ctagataata cttagtaaaa ctttttataa caaaggctag caaagttaaa
      181 gtttattatc tattggaagt taaataaata tgtaaggaat taaaatgaaa aaaagcacag
      241 tattgtcatt aactacagct gcagttattt tagcagccta tgcccctaat gaggtagtct
      301 tagcagacac atctagctct gaagatgctt taagcatctc tgataaagaa aaagtagtag
      361 tagataagga aacagaaaat aaagagaaac ataaagatat tcataatgct atagaaactt
      421 caaaggatac tgaagaaaag aaaacaacaa ttattgagga aaaagaagtt gttagtaaaa
      481 atcctgtaat agacactaaa actagcaatg aagaagcaaa aatcaaagaa gaaaattcca
      541 atcaatccca aggagatcat acggactcat ttgtgaataa aaacacagaa aatcccaaaa
      601 aagaagataa agttgtctat attgctgaat ttaaagataa agaatctgga gaaaaagcaa
      661 tcaagggact atcaaatctt aagaatacaa aagttttata tacttatgat agaattttta
      721 acggtagtgc catagaaaca actccagata acttggacaa aattaaacaa atagaaggta
      781 tttcatcgat tgaaagggca caaaaagtcc aacccatgat gaatcatgcc agaaaggaaa
      841 ttggagttga ggaagctatt gattacctaa agtctatcaa tgctccgttt gggaaaaatt
      901 ttgatggtag aggtatggtc atttcaaata tcgatactgg aacagattat agacataagg
      961 ctatgagaat cgatgatgat gccaaagcct caatgagatt taaaaaagaa gacttaaaag
     1021 gaactgataa aaattattgg ttgagtgata aaatccctca tgcgttcaat tattataatg
     1081 gtggcaaaat cactgtagaa aaatatgatg atggaaggga ttattttgac ccacatggga
     1141 tgcatattgc agggattctt gctggaaatg atactgaaca agatatcaaa aactttaacg
     1201 gcatagatgg aattgcacct aatgcacaaa ttttctctta caaaatgtat tctgacgcag
     1261 gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat tgaagattct atcaaacaca
     1321 acgttgatgt tgtttcggta tcatctggtt ttacaggaac aggtcttgta ggtgagaaat
     1381 attggcaagc tattcgggca ttaagaaaag caggcattcc aatggttgtc gctacgggta
     1441 actatgcgac ttctgcttca agttcttcat gggatttagt agcaaataat catctgaaaa
     1501 tgaccgacac tggaaatgta acacgaactg cagcacatga ggatgcgata gcggtcgctt
     1561 ctgctaaaaa tcaaacagtt gagtttgata aagttaacat aggtggagaa agttttaaat
     1621 acagaaatat aggggccttt ttcgataaga ataaaatcac aacaaatgaa gatggaacaa
     1681 aagctcctag taaattaaaa tttgtatata taggcaaggg gcaagaccaa gatttgatag
     1741 gtttggatct taggggcaaa attgcagtaa tggatagaat ttatacaaag gatttaaaaa
     1801 atgcttttaa aaaagctatg gataagggtg cacgcgccat tatggttgta aatactgtaa
     1861 attactacaa tagagataat tggacagagc ttccagctat gggatatgaa gcggatgaag
     1921 gtactaaaag tcaagtgttt tcaatttcag gagatgatgg tgtaaagcta tggaacatga
     1981 ttaatcctga taaaaaaact gaagtcaaaa gaaataataa agaagatttt aaagataaat
     2041 tggagcaata ctatccaatt gatatggaaa gttttaattc caacaaaccg aatgtaggtg
     2101 acgaaaaaga gattgacttt aagtttgcac ctgacacaga caaagaactc tataaagaag
     2161 atatcatcgt tccagcagga tccacatctt gggggccaag aatagattta cttttaaaac
     2221 ccgatgtttc agcacctggt aaaaatatta aatctacgct taatgttatt aatggcaaat
     2281 caacttatgg ctatatgtca ggaactagta tggcgactcc aatcgtggca gcttctactg
     2341 ttttgattag accgaaatta aaggaaatgc ttgaaagacc tgtattgaaa aatcttaagg
     2401 gagatgacaa aatagatctt acaagtctta caaaaattgc cctacaaaat actgctcgac
     2461 ctatgatgga tgcaacttct tggaaagaaa aaagtcaata ctttgcatca cctagacaac
     2521 agggagcagg cctaattaat gtggccaatg ctttgagaaa tgaagttgta gcaactttca
     2581 aaaacactga ttctaaaggt ttggtaaact catatggttc catttctctt aaagaaataa
     2641 aaggtgataa aaaatacttt acaatcaagc ttcacaatac atcaaacaga cctttgactt
     2701 ttaaagtttc agcatcagcg ataactacag attctctaac tgacagatta aaacttgatg
     2761 aaacatataa agatgaaaaa tctccagatg gtaagcaaat tgttccagaa attcacccag
     2821 aaaaagtcaa aggagcaaat atcacatttg agcatgatac tttcactata ggcgcaaatt
     2881 ctagctttga tttgaatgcg gttataaatg ttggagaggc caaaaacaaa aataaatttg
     2941 tagaatcatt tattcatttt gagtcagtgg aagaaatgga agctctaaac tccaacggga
     3001 agaaaataaa cttccaacct tctttgtcga tgcctctaat gggatttgct gggaattgga
     3061 accacgaacc aatccttgat aaatgggctt gggaagaagg gtcaagatca aaaacactgg
     3121 gaggttatga tgatgatggt aaaccgaaaa ttccaggaac cttaaataag ggaattggtg
     3181 gagaacatgg tatagataaa tttaatccag caggagttat acaaaataga aaagataaaa
     3241 atacaacatc cctggatcaa aatccagaat tatttgcttt caataaccaa gggatcaacg
     3301 ctccatcatc aagtggttct aagattgcta acatttatcc tttagattca aatggaaatc
     3361 ctcaagatgc tcaacttgaa agaggattaa caccttctcc acttgtatta agaagtgcag
     3421 aagaaggatt gatttcaata gtaaatacaa ataaagaggg agaaaatcaa agagacttaa
     3481 aagtcatttc gagagaacac tttattagag gaattttaaa ttctaaaagc aatgatgcaa
     3541 agggaatcaa atcatctaaa ctaaaagttt ggggtgactt gaagtgggat ggactcatct
     3601 ataatcctag aggtagagaa gaaaatgcac cagaaagtaa ggataatcaa gatcctgcta
     3661 ctaagataag aggtcaattt gaaccgattg cggaaggtca atatttctat aaatttaaat
     3721 atagattaac taaagattac ccatggcagg tttcctatat tcctgtaaaa attgataaca
     3781 ccgcccctaa gattgtttcg gttgattttt caaatcctga aaaaattaag ttgattacaa
     3841 aggatactta tcataaggta aaagatcagt ataagaatga aacgctattt gcgagagatc
     3901 aaaaagaaca tcctgaaaaa tttgacgaga ttgcgaacga agtttggtat gctggcgccg
     3961 ctcttgttaa tgaagatgga gaggttgaaa aaaatcttga agtaacttac gcaggtgagg
     4021 gtcaaggaag aaatagaaaa cttgacaaag acggaaatac catttatgaa attaaaggtg
     4081 caggagattt aagaggaaaa atcattgaag tcattgcatt agatggttct agcaatttca
     4141 caaagattca tagaattaaa tttgctgatc aggctgatga aaaggggatg atttcttatt
     4201 acctagtaga tcctgacaaa gatgcttcta aatatgaaaa acttggtgaa atttctgaag
     4261 ataaactcaa aaatgcaaag agcccagagg aaaataccaa taataatcaa gctaaggatg
     4321 aagattcaaa accagatgaa aaaagttcag ttgagggaga agctagcctt gaaataaata
     4381 aaactatttc aacaattaga gagtttgaaa ataaagacct aaagaaactc attaaaaaga
     4441 aatttagaga agttgatgat tttacaagtg aaactggtaa gagaatagag gaatacgatt
     4501 ataaatacga tgataagaga aatattattg cttatgacga tggtagtgcc ttacaatatg
     4561 aaactgaaaa atttgacgaa ataaaatcaa aaatttatgg tgttctaagc ccatctaaag
     4621 atggacactt tgaaattctt ggaaagataa gcaatgtttc taaaaatgcc aaggtatatt
     4681 atggaaatag ctataaatcg atagaaatca aagcgactaa gtatgattca cattcaaaaa
     4741 cgatgatatt tgatttatac gctaatatta atgatattgt agatggatta gcttttgctg
     4801 gagatatgag attatttgtt aaagatgaca atcaaataaa agctgaaact aagattagaa
     4861 tgcctgaaaa aaataaggaa actaaagcag aatatcccta tgtatcaagt tatgggaatg
     4921 taatcgaatt aggagaagga gatctttcaa agaacaaacc agacaattta actaaaatgg
     4981 aatctggtaa aatctattct gattcagaaa aacaacaata tctgttaaag gataacatca
     5041 ttctaagaaa aggctatgca ctaaaagtga ctacctataa tcctggaaaa acggatatgt
     5101 tagaaggaaa tggagtctat agcaaggaag atatagcaaa aatacaaaag gccaatccta
     5161 atctaagagt cctttcagaa acaacaattt atgctgatag tagaaatgtt gaagatggaa
     5221 gaagtaccca agctgtatta atgtcggctt tggacggctt taacattata aggtatcaag
     5281 tgtttacatt taaaatgaac gataaagggg aagctatcga taaagacgga aatcttgtga
     5341 cagattcttc taaacttgta ttatttggta aggatgataa agaatacact ggagaggata
     5401 agtccaatgt agaagctata aaagaagatg gctccatgtt atttattgat accaaaccag
     5461 taaacctttc aatggataag aactacttta atccatctaa atctaataaa atttatgtac
     5521 gaaatccaga attttattta agaggtaaga tttctgataa gggtggtttt aactgggaat
     5581 tgagagttaa tgaatcggtt gtagataatt atttaatcta cggagattta cacattgata
     5641 acactagaga ttttaatatt aagctgaatg ttaaagacgg tgacatcatg gactggggaa
     5701 tgaaagacta taaagcaaac ggatttccag ataaggtaac agatatggat ggaaatgttt
     5761 atcttcaaac tggctatagc gatttgaatg ctaaagcagt tggagtccac tatcagtttt
     5821 tatatgataa tgttaaacct gaagtaaaca ttgatcctaa gggaaatact agtatcgaat
     5881 atgctgatgg aaaatctgta gtctttaaca tcaatgataa aagaaataat ggattcgatg
     5941 gtgagattca agaacaacat atttatgtaa atggaaaaga atatacatca tttgatgata
     6001 ttaaacaaat aacagacaag acactaaaca ttaagattgt tgtaaaagat tttgcaagaa
     6061 atacaaccgt aaaagaattc attttaaata aagatacggg agaggtaagt gaattaaaac
     6121 ctcatagggt aactgtgacc attcaaaatg gaaaagaaat gagttcaacg atagtgtcgg
     6181 aagaagattt tattttacct gtttataagg gtgaattaga aaaaggatac caatttgatg
     6241 gttgggaaat ttctggtttc gaaggtaaaa aagacgctgg ctatgttatt aatctatcaa
     6301 aagatacctt tataaaacct gtattcaaga aaatagagga gaaaaaggag gaagagaata
     6361 aacctacttt tgatgtatcg aaaaagaaag ataacccaca agtaaatcat agtcaattaa
     6421 atgaaagtca cagaaaagag gatttacaaa gagaagatca ttcacaaaaa tctgattcaa
     6481 ctaaggatgt tacagctaca gttcttgata aaaacaatat cagtagtaaa tcaactacta
     6541 acaatcctaa taagttgcca aaaactggaa cagcaagcgg agcccagaca ctattagctg
     6601 ccggaataat gtttatagta ggaatttttc ttggattgaa gaaaaaaaat caagattaag
     6661 acaaaagcta tagaaaaaaa tggtttatgt actgagatta gatagtgagg tgatgacata
     6721 gttttgtgaa aacagccatt tataactcaa ttatttagtt tacttcacta ttgatactat
     6781 ttggagttat taatggactt agtttagata actaatgaat tgattgaaag ggttagtatt
     6841 gacaatattg gtcatattga ttagaaaata gagtctatca aaatttaaag gctaatagag
     6901 gtgatgagac aatttcaagg aattaagtag cgtttggttg cttaattcct ttttatttgg
     6961 aaggaagttt ttcgtaaccg cccaataacg aagtctattg gacggttacg atatgatcac
     7021 tgacttcgtc agtcttatct acaacctcaa aactgtgttt tgagcaacct gcggctagct
     7081 tcctag
//
LOCUS       DBERAE010000065         7028 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.65, whole genome shotgun sequence.
ACCESSION   DBERAE010000065 DBERAE010000000
VERSION     DBERAE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.65"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..306
                     /locus_tag="ACL70N_002017"
     CDS             <1..306
                     /locus_tag="ACL70N_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0590756.1"
                     /translation="APMTYEETMTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGK
                     LELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            367..1329
                     /locus_tag="ACL70N_002018"
     CDS             367..1329
                     /locus_tag="ACL70N_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS0590757.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1506..2513
                     /gene="gap"
                     /locus_tag="ACL70N_002019"
     CDS             1506..2513
                     /gene="gap"
                     /locus_tag="ACL70N_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGS0590758.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2581..3456)
                     /locus_tag="ACL70N_002020"
     CDS             complement(2581..3456)
                     /locus_tag="ACL70N_002020"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0590759.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3543..5738
                     /gene="pbp2a"
                     /locus_tag="ACL70N_002021"
     CDS             3543..5738
                     /gene="pbp2a"
                     /locus_tag="ACL70N_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGS0590760.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5791..5943
                     /gene="rpmG"
                     /locus_tag="ACL70N_002022"
     CDS             5791..5943
                     /gene="rpmG"
                     /locus_tag="ACL70N_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0590761.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5953..6129
                     /gene="secE"
                     /locus_tag="ACL70N_002023"
     CDS             5953..6129
                     /gene="secE"
                     /locus_tag="ACL70N_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGS0590762.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6184..6720
                     /gene="nusG"
                     /locus_tag="ACL70N_002024"
     CDS             6184..6720
                     /gene="nusG"
                     /locus_tag="ACL70N_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGS0590763.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6842..>7028
                     /locus_tag="ACL70N_002025"
     CDS             6842..>7028
                     /locus_tag="ACL70N_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS0590764.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTK"
BASE COUNT         2189 a         1222 c         1530 g         2087 t
ORIGIN      
        1 gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagcttg gtttcagaat
       61 tttctcttac caacattaac cacaccatcg gttattatta tggataatgt aagattccat
      121 agaatgggga agctagaact tttatgcgaa gagtttgggc ataaactgtt acctcttcct
      181 ccctactcgc ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc
      241 aaaaaggtat taccaagttg caataccttt tacgaggctc ttttgtcttg ttcttgtttc
      301 aattgactat agttcacgga tacagttggg aaagaagcta ttaattattt ggagagtcct
      361 tttgggatga acatgtcaaa tattactata gatgggcaag aaatggatct gagtcaaacg
      421 atgccttctt atgctcaagt agtgagtctt tatgaggata caagcatctc tgttagtagt
      481 aatgagacgg acaaagtgtt ggctggatcc ctctatactg atacaaatga acagggatta
      541 atgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa tttgacagct
      601 aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc cgaagctagt
      661 aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga tgacatggag
      721 gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga ggctggattt
      781 acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac aaaagtagta
      841 acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag agttcttgat
      901 attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc atcacaagct
      961 attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat gcaacgttcc
     1021 aaggaaatag gtgtcatgaa agcagttggt tatcagaatc gtggtgtcaa aggaattttt
     1081 atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt ggttgcacaa
     1141 ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat cactaaggtt
     1201 tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt acttggttat
     1261 gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctgtaga atcgttacgc
     1321 tatgaataat aagggattcc ttgatttaca gtcttaaaaa gaaactcaca tagaaaaaca
     1381 atggccatac ttgcaattca actcaaatag ttgtataata ggtttgttga aaggtgattt
     1441 gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata aggaggaaat
     1501 cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt cttgctttcc
     1561 gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt acagatccag
     1621 ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac ggtactgttg
     1681 aagttaaaga aggtggattt gaagttaacg gtaaattcat caaagtttct gctgaacgtg
     1741 atccagaaca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa gctactggtt
     1801 tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa aaagttgtta
     1861 tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caacactaac cacgacgttc
     1921 ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc ttggctccaa
     1981 tggctaaagc tcttcaagac aactttggtg ttgttgaagg attgatgact actatccacg
     2041 cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac cttcgccgtg
     2101 ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgcaaaa gctatcggtc
     2161 ttgtaatccc agaattgaat ggtaaacttg atggatctgc acaacgcgtt ccaactccaa
     2221 ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt gatgaagtga
     2281 acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat ccaatcgtat
     2341 cttcagatat cgtaggtatg tcttacggtt cattatttga cgcaactcaa actaaagttc
     2401 ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac gaaatgtcat
     2461 acactgcaca acttgttcgt actcttgaat acttcgcaaa gattgctaaa taattcttga
     2521 gttgatagaa agcaaggctt tgtggtcttg cttttttata tggaaaaatg gatgacacga
     2581 tcatccattc ttttttaatt ctttttcaaa tgtatttgaa agggtagtga aagttagcct
     2641 ctctaaagta agtgggtggg taaaggaaag tcggaaggca tgaagcataa gccggcttgt
     2701 ctttgattta ctattataga gagggtctcc caggatagga agattatgat gcaaaaggtg
     2761 cacacgaatc tgatgggttc gccctgtctt tagcttgcaa tgagccaagg aagtcttgtt
     2821 tgagaattgc tttaatctgc ttacatgcgt ttcagcatat tgcccatttt ttgcatcaac
     2881 tattcttttt ctacgatcat ggcgatcacg tccaattttg tctctgaaaa caagttcttt
     2941 tctgttgata tttccatcaa ctagagccca atattctcta gaaatctctt ttttctccaa
     3001 taagcgattg agaatgggca ggataaaagg atttttggca aagagaacta agccactggt
     3061 ttccatgtcc agacgatgaa cgacatagca ggtttggcca acataggtac tgacatggtt
     3121 aagaagggca atttcgtttg gttgattacc atgcgttttc atcccctctg gtttgtttac
     3181 aataatcaag tgttgatctt gataaacttc ctgcactaag tctgggttgc cccaagggat
     3241 cgtcttttgg ggataatctt cctcgtcaaa agtcaactgg caaacatctc caggatttac
     3301 gatttcgttc cagcggactt cttcttgatt tatcaaaata tgtttcttga ttctcaaaaa
     3361 atgacggatt tttctaggga tgaggagttg ttcctcaagt aattgcttta ccgtcatttg
     3421 aggtagagag gcgggtaatg taaatgtgaa ttgcatacag atattgtaac aaaaaaagcc
     3481 ctatttggat aggaaatagc taaattcttg tcttcctatg atgaagatga taaaataaac
     3541 gcatgaaatt agataaatta tttgagaaat ttctttctct ttttaaaaaa gaaacaagtg
     3601 aactagagga ctctgattct actatcttac gtcgctctcg tagtgatcga aaaaaattag
     3661 cccaagtagg tccgattcga aaattctggc gtcgttatca tctaacaaag attatcctta
     3721 tactaggttt gagtgcaggc ttgctagttg gaatctattt gtttgctgta gccaagtcga
     3781 ccaatgtcaa tgatttgcaa aatgccttga aaactcggac tcttattttt gaccgtgaag
     3841 aaaaagaggc tggtgccttg tctggtcaaa agggaaccta tgttgagctg actgacatca
     3901 gtaaaaactt gcagaatgct gttattgcga cagaagaccg ttctttctat aaaaatgacg
     3961 ggattaacta tggccgtttc ttcttggcta ttgtcactgc tggacgttca ggtggtggct
     4021 ctaccattac ccaacagctg gctaaaaacg cctatttatc gcaggatcaa actgttgaga
     4081 gaaaagcgaa agaatttttc cttgccttag aattaagcaa aaaatatagt aaggagcaaa
     4141 ttctaaccat gtaccttaac aacgcttatt ttggaaatgg tgtgtggggt gtagaagatg
     4201 cgagtaagaa atactttgga gtttctgcat cagaagtgag tctggatcaa gctgcgactc
     4261 tggcagggat gctcaagggg ccggaactgt ataatccctt gaattccgta gaagattcta
     4321 ctaatcggcg cgatactgtc ttgcagaata tggttgcagc aggatatatt gataaaaacc
     4381 aagaaaccga agctgctgaa gttgatatga cttcgcaatt gcacgataag tatgaaggaa
     4441 aaatctcaga ttaccgttac ccctcttatt ttgatgcggt ggttaatgaa gctgtttcca
     4501 agtataatct aacagaggaa gagattgtca ataatggcta ccgcatttac acagagctgg
     4561 accaaaacta ccaagcaaat atgcagattg tttatgaaaa cacatcgcta tttccgaggg
     4621 cagaggatgg aacgtttgct caatcaggaa gtgtagctct cgaaccgaaa acagggggag
     4681 ttcgtggagt tgtcggtcaa gttgctgaca atgataaaac tggattccgg aatttcaact
     4741 atgcaaccca atcaaagcgt agtcctggtt ctacaattaa gcctttagtt gtttatacgc
     4801 cagcagttga agcaggctgg gctttgaata agcagttgga taaccatacc atgcagtatg
     4861 acagctataa ggttgataac tatgcaggga tcaaaacgag tcgagaagtt cctatgtatc
     4921 aagccttggc agaatcgctt aatctacctg ctgttgccac tgttaatgat ttgggtgtcg
     4981 acaaggcttt tgaggcaggc gaaaaattcg gactcaacat ggaaaaggtc gaccgtgttc
     5041 ttggtgtcgc cttgggaagc ggtgttgaaa ccaaccctct tcaaatggct caagcatacg
     5101 ctgcctttgc aaatgaaggt ttaatgcctg aagctcattt tattagtaga attgaaaatg
     5161 ctagtggaca agttattgcg aatcataaaa attcacaaaa acgggtgatt gataagtctg
     5221 tagctgacaa gatgaccagt atgatgttgg ggactttcac caacggtacc ggtattagtt
     5281 catcgcctgc agactatgtc atggcaggga aaactggaac aactgaagca gttttcaatc
     5341 cggagtacac aagtgaccag tgggtaattg gttatactcc ggatgtagtg attagccact
     5401 ggcttggctt tccgaccact gatgaaaatc actatctagc tggctctact tcaaacggtg
     5461 cagctcatgt ctttagaaac attgccaata ccattttacc ttatacgcca ggaagtacct
     5521 ttacggttga aaatgcttat aagcaaaatg gaattgcacc agccaataca aaaagacaag
     5581 tacaaaccaa tgataatagc cagacagatg ataatttgtc tgatattcga gggcgtgcgc
     5641 aaagtctagt agatgaggct agccgggcta tctcagatgc gaagattaag gaaaaggctc
     5701 aaacaatatg ggattcgata gtcaatctat ttcgctaaga tgcttgtcaa agcctagctt
     5761 tcttgttata atggataaga tggaggcgtt atggcactaa aaaaagcaag cctagcttgt
     5821 gcggtttgtg gttcgagaaa ctattcaatc aagatcagcg gaaaccccaa gcctacacga
     5881 ctagaagtaa ataaattttg taagcattgt ggcaagtaca ctacacacag agaaacgaga
     5941 taggagagag cgatgcgttt tattggagat atttttagac ttcttaaaga cacaacatgg
     6001 ccaactcgca aggaaagctg gagagatttt cgttctatca tggaatacac agctttcttt
     6061 gtagtaatta tttacatttt tgaccagttg attgtttcag gtttgattcg atttattaac
     6121 attttttaga agattagtgg agttaattac actagaaatc ttctatttat gaaaggaaat
     6181 atcatggata gttttgataa aggatggttt gttttacaaa cttattctgg ttatgaaaat
     6241 aaggtgaaag aaaatctatt acaacgtgca caaacctaca atatgttgga taatattcta
     6301 cgcgttgaaa ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag aaaagaagta
     6361 gaagaaaatc gctttccagg ttatgttctt gtagaaatgg tcatgacaga tgaagcttgg
     6421 tttgttgttc gaaacacacc aaatgttaca ggatttgtcg gatcacacgg gaacagatca
     6481 aaaccaactc cattattgga acaagaaatt cgtgacattt tggtatctat gggacaaact
     6541 gttcaagaat ttgatttcga tgttgagatt ggtcaaactg tacgtattat tgatggtgct
     6601 tttgcagact acactggtaa gattacagaa attgataata acaaagtgaa aatgattatc
     6661 tctatgtttg gtaatgacac agttgcagaa gtaaacctaa accaaatcgc agaattataa
     6721 ccctgagaga ggctggagcc tctctttttt gtgcagttta ggagctaaag ggaacagaat
     6781 ggagaaaatg gaacaaatgt gttttctaat ctgttagact gtatctagaa aggggaaaat
     6841 tatgattaaa gaattgtatg aagaagtcca agggactgtg tataagtgta gaaatgaata
     6901 ttaccttcat ttatgggaat tatcggattg ggaccaagaa ggcatgctct gcttacatga
     6961 attgattagt agagaagaag gactggtaga cgatattcca cgtttaagga aatatttcaa
     7021 aaccaagt
//
LOCUS       DBERAE010000066         6994 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.66, whole genome shotgun sequence.
ACCESSION   DBERAE010000066 DBERAE010000000
VERSION     DBERAE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.66"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(298..1989)
                     /gene="argS"
                     /locus_tag="ACL70N_002026"
     CDS             complement(298..1989)
                     /gene="argS"
                     /locus_tag="ACL70N_002026"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGS0590765.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2125..2571
                     /gene="argR"
                     /locus_tag="ACL70N_002027"
     CDS             2125..2571
                     /gene="argR"
                     /locus_tag="ACL70N_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0590766.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2622..5156
                     /gene="mutS"
                     /locus_tag="ACL70N_002028"
     CDS             2622..5156
                     /gene="mutS"
                     /locus_tag="ACL70N_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGS0590767.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5303..>6994
                     /locus_tag="ACL70N_002029"
     CDS             5303..>6994
                     /locus_tag="ACL70N_002029"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0590768.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1894 a         1368 c         1657 g         2075 t
ORIGIN      
        1 tatttggtta ggtgaattag tgaagtgttt aggcaagtgt ctctggttac gacgtcatgg
       61 cctctaaatc gattatattt aggggtcatg actagtgaag cagttagcta gttcgcatat
      121 aagcggctag cgtctaacaa ttaggaactt tagttccaat aactttaaga ttacgacgtt
      181 ttaggacata aatcgatcat atttatgtcc taaaactagt gaagcgccta gccaaagtcc
      241 gaataggatt tggcgttagt tacttagatt gctttgcaat caagtaactt tggcgattta
      301 catcttctct ggcgcttcta ctccaagcaa gcgaagggct tctttgagaa cgactgcggt
      361 tgcgtagctg agggctagac ggctgtcgcg ttctgggctt tcatccaaga tacgtgtatg
      421 tgcatagtat ttgttaaagg attgagccag gctaattgca aatttagcaa tgatagaagg
      481 ttcaaagtta tctgccgcac ggttgataat acgtgggaag tcttgaatga gtttaatgat
      541 ttcccagctt tcagtatcat tcaagctata gttgccagct gtttctggtt tgaaatcggc
      601 tttgcgtaag atagattgga tacgagcgta ggcatattga acgtaaggtc cagtttcacc
      661 ctcgaaggat accatagctt ctaggtcgaa gtcgtatcca tttgtacggt cagttttgag
      721 gtcatagaat ttaatggctc caaccccaac agcatgtgct acttggtctt tgttttctag
      781 ttcaggattt ttagcctcga tttggacctt ggcacggcta acagcctctg caacagtagg
      841 ctctagcaag atgacattcc ctttacgagt agagagcttc ttcccttctt ttgtaaccag
      901 accaaaagga acgtgggtaa tgtcgtcact ccaatcgtag cccatctctt gcaagacagc
      961 tttgagttgt ttaaagtggg cagattgctc ttgaccaacg acgtagatag atttagcaaa
     1021 ttggtattca tttttacggt agagggctgc agccaagtca cgtgtgatat agagagttgc
     1081 accatcagac ttcttgatga gggctggatg ttcaattcca tatttctcaa gattcacaac
     1141 ttgggcacct tctgattcaa gaagtagtcc tttttcagaa agaatgtcta caactgcatc
     1201 catcttatca ttgtagaagg cttctccgtt atagctgtca aattcaacct tcaattcatt
     1261 gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac cattgccaaa gagcgagagc
     1321 ttcctcatct ccattttcaa gtttacggaa ccattcgcgc gcttcttcat ccaagctagg
     1381 gtcattttca gcttcagcgt tgatgcggac atagagttta aggagttcat cgattggatg
     1441 agcttttaca gcttcttcgt cgccccattt tttgtaggca acaatcaaca tcccaaattg
     1501 tttaccccag tctcccaaat ggttgacctt gaccgtttga taaccgattt tttggaaaat
     1561 atgtgacaag ctatctccga taacagttga acgcaggtgg ccaatagaaa atggtttagc
     1621 gatattcgga ctagacatgt cgataacaac attttcttgt ttgccaatat tttggtcagc
     1681 atagtgttct ttttcagtgg taacagcttg caatacttga gcagaaatgg cagatttatc
     1741 aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt tcaaaggctt ggctgttcat
     1801 tttttcagcc agttcagccg caatcatttg tggtgcttta cgttcgactt ttgcaagaga
     1861 aaaagcaggg aaagcaatgt ctcccatttc tgagttttta ggggtttcca gtaactttaa
     1921 aatagcctct tggtccaggc tatcaatgat gctagataat tcgctagcaa tcaattcttt
     1981 tgtattcatt aagagctcct ttttggactt ttctactatt ttatcacaat tttaaagaaa
     2041 gaagaaaaaa tttttgaaat ctcctgtttt tttggtataa tatggttata aatatagtta
     2101 taaatatgca cgcaagagga ttttatgaga aaaagagatc gtcatcagtt aataaaaaaa
     2161 atgattactg aggagaaatt aagtacacaa aaagaaattc aagatcggtt ggaggcgcac
     2221 aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc gcgaaatcgg cttgaccaag
     2281 gtcaagaaaa atgatatggt gtattatgta ctagtaaatg agacagaaaa gattgatttg
     2341 gtggaatttt tgtctcatca tttagaaggt gttgcaagag cagagtttac cttggtgctt
     2401 cataccaaat tgggagaagc ctctgttttg gcaaatattg tagatgtaaa caaggatgaa
     2461 tggattttag gaacagttgc tggtgccaat accttattgg ttatttgtcg agatcagcac
     2521 gttgccaaac tcatggaaga tcgtttgcta gatttgatga aagataagta aggtcttggg
     2581 agttgctctc aagacttatt tttgaaaagg agagacagaa aatggcgata gaaaagttat
     2641 cacccggcat gcaacagtat gtggatatta aaaagcaata tccagatgct tttttgctct
     2701 ttcggatggg tgatttttat gaattatttt atgaggatgc ggtcaatgct gcgcagattc
     2761 tggaaatttc cttaacgagt cgcaacaaga atgccgacaa tccgatccct atggcgggtg
     2821 ttccctatca ttctgcccaa cagtatatcg atgtcttgat tgagcagggt tataaggtgg
     2881 ctatcgcaga gcagatggaa gatcctaaac aagcagttgg ggttgttaaa cgagaggttg
     2941 ttcaggtcat tacgccaggg acagtggtcg atagcagtaa gccggacagt cagaataatt
     3001 ttttggtttc catagaccgc gaaggcaatc aatttggcct agcttatatg gatttggtga
     3061 cgggtgactt ttatgtgaca ggtcttttgg atttcacgct ggtttgtggg gaaatccgta
     3121 acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc tgaggaagaa gaacaaatcc
     3181 tcagccgcca gatgaatctg gtactctctt atgaaaaaga aagctttgaa gaccttcatt
     3241 tattggattt gcgattggca acggtggagc aaacggcatc tagtaagctg ctccagtatg
     3301 ttcatcggac tcagatgagg gaattgaacc acctcaaacc tgttatccgc tacgaaatta
     3361 aggatttctt gcagatggat tatgcgacca aggctagtct ggatttggtt gagaatgctc
     3421 gctcaggtaa gaaacaaggc agtcttttct ggcttttgga tgaaaccaaa acggctatgg
     3481 ggatgcgtct cttgcgttct tggattcatc gccccttgat tgataaggaa cgaatcgtcc
     3541 aacgtcaaga agtagtgcag gtctttctcg accatttctt tgagcgtagt gacttgacag
     3601 acagtctcaa gggtgtttat gacattgagc gcttggctag tcgtgtttct tttggcaaaa
     3661 ccaatccaaa ggatctcttg cagttggcga ctaccttgtc tagtgtgcca cggattcgtg
     3721 cgattttaga agggatggag caacctactc tagcctatct catcgcacaa ctggatgcaa
     3781 tccctgagtt ggagagtttg attagcgcag cgattgctcc tgaagctcct catgtgatta
     3841 cagatggggg aattatccgg actggatttg atgagacttt agacaagtat cgttgcgttc
     3901 tcagagaagg gactagctgg attgctgaga ttgaggctaa ggagcgagaa aactctggta
     3961 tcagcacgct caagattgac tacaataaaa aggatggcta ctattttcat gtgaccaatt
     4021 cgcaactggg aaatgtgcca gcccactttt tccgcaaggc gacgctgaaa aactcagaac
     4081 gctttggaac cgaagaatta gcccgtatcg agggagatat gcttgaggcg cgtgagaagt
     4141 cagccaacct cgaatacgaa atatttatgc gcattcgtga agaggtcggc aagtacatcc
     4201 agcgtttaca agctctagcc caaggaattg cgacggttga tgtcttacag agtctggcgg
     4261 ttgtggctga aacccagcat ttgattcgac ctgagtttgg tgacgattca caaattgata
     4321 tccggaaagg gcgccatgct gtcgttgaaa aggttatggg ggctcagacc tatattccaa
     4381 atacgattca gatggcagaa gataccagta ttcaactggt tacagggcca aacatgagtg
     4441 ggaagtctac ctatatgcgt cagttagcca tgacggcggt tatggcccag ctgggttcct
     4501 atgttcctgc tgaaagcgcc catttaccga tttttgatgc gatttttacc cgtatcggag
     4561 cagcagatga cttggtttcg ggtcagtcaa cctttatggt ggagatgatg gaggccaata
     4621 atgccatttc gcatgcgacc aagaactctc tcattctctt tgatgaattg ggacgtggaa
     4681 ctgcaactta tgacgggatg gctcttgctc agtccatcat cgaatatatc catgagcaca
     4741 tcggagctaa gaccctcttt gcgacccact accatgagtt gactagtctg gagtctagtt
     4801 tacaacactt ggtcaatgtc cacgtggcaa ctttggagca ggatgggcag gtcaccttcc
     4861 ttcacaagat tgaaccggga ccagctgata aatcctacgg tatccatgtt gccaagattg
     4921 ctggcttgcc agcagacctt ttagcaaggg cggataagat tttgactcag ctagagaatc
     4981 aaggaacaga gagtcctcct cccatgagac aaactagtgc tgtcactgaa cagatttcac
     5041 tctttgatag ggcagaagag catcctatcc tagcagaatt agctaaactg gatgtgtata
     5101 atatgacacc tatgcaggtt atgaatgtct tagtagagtt aaaacagaaa ctataaaacc
     5161 aagactcact agttaatcta gctgtatcaa ggagacttct ttgacaattc tccacttttt
     5221 tgctagaata acatcacaca aacagaatga aaaggagctg acgcattgtc gctccctttt
     5281 gtctattttt taaggagaaa gtatgctgat tcagaaaata aaaacctaca agtggcaggc
     5341 cctggcttcg ctcctgatga caggcttgat ggttgctagt tcacttctgc aaccgcgtta
     5401 tctgcaggaa gtcttaggcg ccctccttac tgggaaatat gaagttattt atagtatcgg
     5461 ggcttggttg attggtgtgg ccgtagtcgg tctagttgct ggtggactca atgttgtcct
     5521 cgcagcctat attgcccaag gagtttcatc cgaccttcgg gaggatgcct tccgtaaaat
     5581 tcaaaccttt tcttatgctg atattgaaca atttaatgcg ggaaatctag tcgttcgaat
     5641 gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg accttccaaa ttcttttcag
     5701 acttcccctc ttgttcatcg gttcgtttat cctagcggtt caaaccttac cttctctgtg
     5761 gtgggtgatt gttctcatgg tagtcttgat ttttggtttg actgctgtca tgatgggaat
     5821 gatggggcct cgttttgcta aatttcaaac ccttcttgag cgcatcaatg ccattgccaa
     5881 ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc caagaaaaag agcaatttgc
     5941 taagtttaca gaggtctcag acgagcttct tggtcaaaac ctttacattg gttatgcctt
     6001 ttcagtagtg gaacccttta tgatgttggt tggttacggg gcggtcttcc tctctatttg
     6061 gctggtcgcg ggaatggttc agtcggatcc gtctgttgtt ggttccatcg cttcttttgt
     6121 taattaccta agccagatta tctttaccat tgttatggtt ggatttttgg gaaattctgt
     6181 cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt cttgacgcag agccagctat
     6241 gaccttcaag gatatcccag atgaagagtt ggttggaagt cttagctttg aaaatgtgac
     6301 ctttacctat ccaatggaca aggaaccgat gctgaaagat gtgagcttta ctattgaacc
     6361 tggtcaaatg gttggtgtag ttggagcgac tggtgcagga aagtcaacct tggctcaatt
     6421 gattccacgt ctctttgatc cacaggacgg ggccattaaa atcggtggca aggatattcg
     6481 agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc gttctccaac gtgccattct
     6541 ttttagtgga acgattgcag ataacttgag acaggggaag gggaatgcta ctctatttga
     6601 aatggagcgc gcagccaata ttgcccaggc tagtgaattc attcatcgta tggagaaaac
     6661 ctttgaaagt ccagttgaag aacggggaac caatttctct ggtggacaaa aacaaaggat
     6721 gtcgattgcg cgtgggattg tcagcaatcc acgtattctg atttttgacg attcgacctc
     6781 agccttggat gccaaatcag agcgcttggt gcaagaagct ttgaataagg acttgaaggg
     6841 gacgacaacc attattattg ctcaaaaaat tagctcggtt gtccatgcag acaagatctt
     6901 ggttctaaat caaggacgat tgattggtca aggcacgcat gcagacttgg ttgccaacaa
     6961 tgccgtttac cgtgaaatct atgaaacaca gaaa
//
LOCUS       DBERAE010000067         6714 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.67, whole genome shotgun sequence.
ACCESSION   DBERAE010000067 DBERAE010000000
VERSION     DBERAE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.67"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(55..318)
                     /locus_tag="ACL70N_002030"
                     /pseudo
     CDS             complement(55..318)
                     /locus_tag="ACL70N_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            512..2278
                     /gene="patB"
                     /locus_tag="ACL70N_002031"
     CDS             512..2278
                     /gene="patB"
                     /locus_tag="ACL70N_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGS0590769.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTENKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2417..3106
                     /locus_tag="ACL70N_002032"
     CDS             2417..3106
                     /locus_tag="ACL70N_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS0590770.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQIGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3110..3289
                     /locus_tag="ACL70N_002033"
     CDS             3110..3289
                     /locus_tag="ACL70N_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590771.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3276..4625
                     /locus_tag="ACL70N_002034"
     CDS             3276..4625
                     /locus_tag="ACL70N_002034"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGS0590772.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4749..6209
                     /gene="gltX"
                     /locus_tag="ACL70N_002035"
     CDS             4749..6209
                     /gene="gltX"
                     /locus_tag="ACL70N_002035"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGS0590773.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYSRHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6223..6657
                     /locus_tag="ACL70N_002036"
     CDS             6223..6657
                     /locus_tag="ACL70N_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0590774.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2108 a         1298 c         1442 g         1866 t
ORIGIN      
        1 ggccttaaaa gcaggtgaaa agcgagcgca tgctttggca gcttgtatga gtgcctaccg
       61 cagatgaggg gaaccccgtt tgatcattct tccagctaaa tcaatctgac ctgactgata
      121 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
      181 attttgaatc tcggctaaaa tgaccgcccc taaacgattc ccaatcccag taaccgtcgt
      241 gatgaccgaa tttaactcag ccatcaagtc attgacacat ttttccgcct tgtcaatgag
      301 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtctatgcg ttatcaaact
      361 cattaccaat taaaacaaat gtggttagat cctttcggaa attgtcaagc gattggagga
      421 aatgaactaa tccacagcgg cttattccaa gtataccact tgggctttgg cagtagctaa
      481 ctgcgctaaa tataatataa ggaggagtaa aatgaagaca gttcaatttt tttggcatta
      541 ttttaaggtc tacaagttct catttgtagt tgtcatcctg atgattgttc tggcgacttt
      601 tgcccaagcc ctctttccag tcttttctgg acaagcggtg acgcagctag ccaatttagt
      661 tcaagcttat caaaatggca atccagaact tgtatggcaa agcctatcag gaatcatggt
      721 caatcttggc ctgctggttt tggttctatt tatctctagt gtaatataca tgtgtctcat
      781 gacgcgcgtg attgcagaat cgaccaacga gatgcgcaaa ggtctctttg gtaagcttgc
      841 tcagttgacg gtttctttct ttgaccgtcg acaagatggc gatatcctgt ctcattttac
      901 cagtgatttg gataatatcc tccaagcctt taacgaaagc ttgattcagg tcatgagcaa
      961 tattgtttta tacattggtc tgattcttgt catgttttcg agaaatgtga cgctggctct
     1021 catcaccatt gccagcaccc cattggcttt ccttatgctg attttcatcg tgaaaatggc
     1081 acgcaaatac accaacctcc agcagaaaga ggtagggaag ctcaacgcct atatggatga
     1141 gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt caagaggata tgatggcagg
     1201 atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt aaaggaagaa tgttctcagg
     1261 aattcttttc cctgtcatga atgggatgag cctgattaat acagccatcg tcatctttgc
     1321 tggttcggct gtacttttga atgataagtc tattgaaaca agtacagccc taggtttgat
     1381 tgttatgttt gcacaatttt cacagcagta ctaccagcct attatccaag ttgcagcgag
     1441 ttggggaagc cttcagttgg cctttactgg agctgaacga attcaggaaa tgtttgatgc
     1501 agaggaggaa atccgacctg aaaaggctcc aaccttcact aagttgcaag aaagtgttga
     1561 aatcagtcat atcgattttt catacttgcc tgataaacct attttgaaag atgtcagcat
     1621 ttctgcccct aaaggccaga tgacagcagt tgttgggccg acaggttcag gaaaaacgac
     1681 tattatgaac ctcatcaatc gcttttatga tgttgatgct ggtggtattt attttgatgg
     1741 taaagacatt cgtggctatg acttagatag tcttagaagc aaggtgggaa ttgtattgca
     1801 agattcggtc ttgtttagcg gaacgattcg agacaatatc cgatttggtg tgccagatgc
     1861 tagtcaggaa atggttgagg tagcagcaaa agcaacccac attcacgact atatcgaaag
     1921 tttgcctgat aagtacgata ctcttattga tgatgaccag agcatctttt caacagggca
     1981 gaagcaattg atttcaatcg ctcgaaccct gatgacagat ccagaagttc tcattctcga
     2041 tgaagcaact tcaaacgtag atacggtgac agaaaacaag attcagcatg ccatggaggt
     2101 ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc ttgaaaacca ttctcaatgc
     2161 agatcagatt attgtcctta aagatggaga agtcattgaa cgtggtaacc accatgaact
     2221 tttgaagcta ggtggctttt attcagaact ctatcacaat caatttgttt tcgaataaga
     2281 aagaagttgt cctatgtggg cagctttttc ttgtccataa aaaatgttta tcacagcctt
     2341 aaaaaaaaca tattagacga aagtcatttt gagtgatatg ataggactat cgttagcatt
     2401 cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt gctgcaaatc tatgtcccgt
     2461 agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt agattcgcag agatcattcg
     2521 tcaaatcggt ggtctccctt tagtcattcc tgttggtgat gagtcagttg tacgtgatta
     2581 tgtggaaatg attgacaaac tcattttgac aggaggccaa aatgttcatc ctcagtttta
     2641 tggagagaaa aagaccgtcg agagcgatga ttacaatctg gtccgtgacg aatttgaatt
     2701 ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt atggcaatct gtcgcggtgt
     2761 ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa gaaatcgaag gtcactggca
     2821 aggactacct ttcgggacat ctcactctat tgagacagta gaaggaagcg tggtggctaa
     2881 gctatttggg aaagaaagtc aggtcaactc agtccatcgt caaagcatta aagatttggc
     2941 acctaatttc cgtgtaactg ctattgattc aagagaccaa actattgaag cgattgagtc
     3001 tatcgacgag caccgcatta tcggtttaca gtggcatcca gagtttctgg ttaatgaaga
     3061 agatggcaat ttagaattat ttgagtattt attgaatgaa ctgtaacgat tggaacatct
     3121 ggtcgttctt tcttttattt tttcaaaatt tttagaatgt ggcattttac gcaaacgttt
     3181 gaattctgat aaaaattgga gaaattcgac aaaaaaactt gaaaaaaacg aaggtaagcg
     3241 ttatgataga aaagaagaaa tattggagga agaacatgtc acatattaaa tttgattatt
     3301 caaaagtttt agacaaattt gttgcaccac atgaagtgga atacatgcaa tcacaagtaa
     3361 cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg tagcgacttc ttgggatggt
     3421 tggaccttcc tgaaaaatac gatcgcgaag aatttgaccg catcttgaaa gctgctgagc
     3481 aaatcaagtc agacagcgat gttttggttg tgatcggtat tggtggatct taccttggtg
     3541 caaaagcagc aatcgacttc ttgaatcacc attttgctaa cttgcaaaca aaagaagaac
     3601 gcaaagctcc acaaatcctt tacgcaggaa actcaatctc atctacttac cttgctgact
     3661 tggtagagta tgttgcagac aaagacttct cagtaaacgt aatttctaaa tcaggtacaa
     3721 caactgaacc agcgattgct ttccgtgtct ttaaagaact cttggttaag aaatacggtc
     3781 aagaagaagc taacaaacgt atctatgcaa caactgaccg ccaaaagggt gctgttaagg
     3841 ttgaagcaga cgctaacggt tggggaacat ttgttgttcc agatgatatc ggtggacgct
     3901 tctcagtatt gacagccgtt ggtttgcttc caatcgcagc atcaggagct gacatcaaag
     3961 ctcttatgga aggtgcgaat gcagctcgca aagactacac ttcagacaaa atctctgaaa
     4021 acgaagctta ccaatacgca gctgttcgga acatccttta tcgtaaaggc tatgcaactg
     4081 agatcttggt aaactatgag ccatcacttc aatacttctc agaatggtgg aaacaattgg
     4141 ctggtgaatc agaaggaaaa gaccaaaaag gtatctaccc aacttcagcc aacttctcaa
     4201 ctgacttgca ctcacttggt caatttatcc aagaaggaac tcgtatcatg tttgaaacag
     4261 ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc tactttggaa gaagaccttg
     4321 acggacttgg ttaccttcaa ggaaaagacg ttgactttgt aaacaaaaaa gcaactgacg
     4381 gtgttcttct tgcccacaca gatggtgatg taccaaacat gtatgtgact cttccagagc
     4441 aagacgcttt cactcttggt tacactatct acttcttcga attggcaatt gccctttcag
     4501 gttacttgaa tgctatcaac ccatttgacc aaccaggtgt tgaagcttat aaacgtaaca
     4561 tgtttgccct tcttggaaaa ccaggatttg aagaattgag caaagaactt aacgcacgtc
     4621 tataatagaa gaaaagagtg gtttgcccac tctttttact ctctttatcc atagaaattg
     4681 gactcagcca agacttgtga tataatatag aaagcaaaaa ggcagacgcc tagataatag
     4741 gagaaactat gtcaaaagat atccgcgtac gttacgcacc aagtccaaca ggactactac
     4801 acatcggaaa tgctcgtaca gcattgttta attacttgta ttcgcgccat catggtggaa
     4861 catttctcat ccgtatcgaa gatactgacc gtaaacgcca tgtcgaggat ggtgaacgtt
     4921 cacaacttga aaaccttcgc tggttaggca tggattggga tgaaagtcca gaatcacatg
     4981 agaattatcg ccagtctgag cgtttggact tgtatcaaaa atacattgac caactattag
     5041 ctgaaggaaa agcctataaa tcttacgtta cagaagaaga gttggcagct gaacgcgaac
     5101 gccaagaagt agctggcgaa acaccacgct acatcaatga ataccttggt atgagtgaag
     5161 aagaaaaagc agcttacatc gcagaacgtg aagcagcagg gatcatccca actgttcgtt
     5221 tggctgtcaa tgagtcaggt atctacaagt ggcatgatat ggtcaaaggc gatatcgaat
     5281 ttgaaggtgg caatatcggt ggtgactgga ttatccaaaa gaaagacggt tacccaactt
     5341 acaactttgc cgttgccatc gatgaccatg atatgcaaat ctctcatgtt atccgtggag
     5401 acgaccatat tgctaacaca ccaaaacagc tcatggttta tgaagcactt ggttgggaag
     5461 ctccagagtt tggtcacatg accttgatta tcaactctga gactggtaag aagttatcta
     5521 aacgtgatac taatacactt caatttatcg aagattaccg aaagaaaggt taccttccag
     5581 aagcagtctt taactttatt gctcttcttg gttggaaccc aggtggtgaa gatgagattt
     5641 tctctcgtga agaactcatt aaactttttg atgaaaaccg cctcagcaag tcaccagcag
     5701 cctttgatca gaaaaaacta gactggatga gcaatgatta tatcaagaat gcagaccttg
     5761 aaaccatctt tgaaatggca aaaccattct tagaggaagc aggccgtttg actgacaagg
     5821 ctgaaaaatt agttgagctc tataaaccac aaatgaaatc agtagatgag attatcccat
     5881 tgacagatct tttcttctca gatttcccag aattgacaga agcagagcgc gaagtcatga
     5941 cgggtgaaac agttccaaca gttcttgaag cattcaaagc aaaacttgaa gcgatgacag
     6001 atgataaatt tgtgacagaa aatatcttcc cacaaattaa agcagttcaa aaagaaacag
     6061 gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc agtttcaggc gaaatgcatg
     6121 ggccagaatt accagataca attttcttgc ttggacgtga aaaatcaatt cagcatatcg
     6181 aaaacatgct aaaagaaatc tctaaataaa gaggatacaa taatggacat ctgggaaaag
     6241 atgtacgaag aagcacagaa actatacaat ccacatgaag tatcagactt tgtttatgcc
     6301 aatcatgttg tagctgcagt agaagcagaa gatggacaaa tatttacagg attctgtatg
     6361 gagggaacct gtggtgtttt ccatctctgc gcagaacggg cggccctctt caatatgtac
     6421 caattttcag gacaaactaa ggttaagaaa gtattagcct ttcgagacaa accaccttat
     6481 ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat tccttttaga gcttaatgct
     6541 gaaaataaag atgcagaatt catgatggac tataatataa gaaaaacagt taaagtcgca
     6601 gaactaatcc cttattggtg gggagaagaa cgtgcttcta agtttaatga gcgatagaag
     6661 agtcagtata attctggctt tttttactat aagttgaaaa aataaaaaaa atta
//
LOCUS       DBERAE010000068         6418 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.68, whole genome shotgun sequence.
ACCESSION   DBERAE010000068 DBERAE010000000
VERSION     DBERAE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.68"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..378
                     /locus_tag="ACL70N_002037"
                     /pseudo
     CDS             1..378
                     /locus_tag="ACL70N_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            545..745
                     /locus_tag="ACL70N_002038"
     CDS             545..745
                     /locus_tag="ACL70N_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590775.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            787..1191
                     /locus_tag="ACL70N_002039"
     CDS             787..1191
                     /locus_tag="ACL70N_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGS0590776.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1422..2129
                     /gene="ccdA2"
                     /locus_tag="ACL70N_002040"
     CDS             1422..2129
                     /gene="ccdA2"
                     /locus_tag="ACL70N_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS0590777.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDFNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2140..2697
                     /gene="sdbB"
                     /locus_tag="ACL70N_002041"
     CDS             2140..2697
                     /gene="sdbB"
                     /locus_tag="ACL70N_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGS0590778.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3071..4462
                     /locus_tag="ACL70N_002042"
     CDS             3071..4462
                     /locus_tag="ACL70N_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGS0590779.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4605..5522
                     /gene="adcAII"
                     /locus_tag="ACL70N_002043"
     CDS             4605..5522
                     /gene="adcAII"
                     /locus_tag="ACL70N_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGS0590780.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5530..>6418
                     /gene="phtB"
                     /locus_tag="ACL70N_002044"
     CDS             5530..>6418
                     /gene="phtB"
                     /locus_tag="ACL70N_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGS0590781.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLI"
BASE COUNT         1968 a         1156 c         1360 g         1934 t
ORIGIN      
        1 actaccatcc actatgcgtt caaagctatg ggctacactc gaaaaaaaga accacaccta
       61 ctatgaacaa gacccagaaa agtagcctta tttcttaaga attttaatag tttaaagcac
      121 ctagcacctg tttagattga tgaaacagga ttcgatactt atttttatcg agaatatggt
      181 cgctcattaa aaggtcagtt aagaagaggc aaagtatctg gaagaagata tcagaggatt
      241 tctttggttg caggtctaac aaatggtgaa ttaatcgctc caatgactta cgaagagatg
      301 atgacgagcg acttttttga agtatggttt cagaagtttt tcttaccaac attaaccaca
      361 ccatcggtta ttatagtaaa atgaaataag aataggacaa atcgatcagg acagtaaaat
      421 cgaattctaa caatgtttta gaagtccata tgtactattc tagtttcaat ataccataac
      481 tgttcctagt caacctgcaa gccctgtccc agctccaagc tcagctccga ctcaagatcc
      541 tagagtggta gcaagcgctt cggctagctc aacgagcaca caagctcaag agcaagttga
      601 caagtctgaa cttcgtgcct tgagtcaaga gttagaccaa cgcttgaaag ctttggcaac
      661 agtatctgat ccgaaaatcg atgcaaccaa ggctgtcctc ctagatgctc aaaaagctcc
      721 ggaagatagt gccttgacag agtaaggtct gcatactgca gtagagtctg tgaaggctgg
      781 gctgccttgg actctctcaa agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag
      841 gacaagaagg atgcaaaaca aggaacggaa gatagtaagg attcagataa gatgactgaa
      901 acaaactcag ttccggcagg agtgattgtg gtcagtctac ttgccctcct aggcgtgatt
      961 gccttctggc tgattcgccg taagaaagag tcagaaatcc agcaattaag cacggaattg
     1021 atcaaggttc taggacagct agatgcagaa aaagcggata aaaaagtcct tgccaaagcc
     1081 caaaaccttc tccaagaaac ccttgatttc gtgaaagaag aaaatggctc agcagagaca
     1141 gaaactaaac tagtagagga gcttaaagca atccttgaca aactcaagta aaacatgatt
     1201 tatgaaatgt cagacctaaa agacattttc gttcacaaaa gcagcgatga gtaatccttg
     1261 tcgttgcttt ttggctattt tgggggataa gatccgcctt gactagcaaa agaaaagatt
     1321 ggtccaatag tgcccgatac gattttgcgt agcagaaagc ttacaaataa aattgaatat
     1381 agtaaaatag gattagaatt attaagaaag ttggttcttt attggaaacg atagtatttt
     1441 taatctctgt ttttctagca ggtgttttat cctttttttc tccttgtatt tttcctcttc
     1501 tgccagtcta tgctgggatt ttattggatg atcaagaaag tgcaaaaagc ttttctttgt
     1561 ttgggagaaa ggttctctgg tcaggcttga ttcgaacact ttgctttatc gctggtatct
     1621 ctctcatttt ctttattcta ggctttggtg ctggttactt tggtcatatt ctctatgcaa
     1681 attggtttcg atatgtcatg ggagctatta ttatcatttt gggtcttcac cagatggaaa
     1741 tttttcattt gaagaaatta gaagttcaaa aaagttttac ctttaaaaaa tcagatttta
     1801 atcgttattg gtcagctttt ttacttggta ttacctttag ctttggttgg acaccttgta
     1861 ttggtccagt tttaagttct gttttagcac ttgcggcttc tggaggcaat ggtgcttggc
     1921 aaggagcgat ttatactctc atttacactc tgggcatggc ccttcctttc ttggtcttgg
     1981 cactagcttc aggtctagtc atgccatatt ttagtaaaat caagcgtcat atgatgctac
     2041 taaagaaaat tggtggtttc ctcattgttt taatgggaat tttgttacta ttaggacaag
     2101 taaatgttct agctggaatt tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct
     2161 ggcttaagtc tcttgtcatt agttgtattg atggcctgtg gtgaggaaga aactaaaaag
     2221 actcaagcag cacaacagcc aaaacaacaa acgactgtac aacaaatttc tgttggaaaa
     2281 gatgctccag actttacatt gcaatccatg gatggcaaag aagttaagtt atctgatttt
     2341 aagggtaaaa aggtttactt gaagttttgg gcttcatggt gtggtccatg caagaaaagt
     2401 atgccagagt tgatggaact agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc
     2461 attgcaccag gaattcaagg tgaaaaaact gttgagcaat tcccacaatg gttccaggaa
     2521 caaggatata aggatatccc agttctttat gataccaaag caaccacctt ccaagcttat
     2581 caaattcgaa gcattcctac agaatattta attgatagcc aaggaaagat tggaaagatt
     2641 caatttggtg ctatcagtaa tgcggatgca gaagcagcat ttaaagaaat gaactagaat
     2701 cgataaaatc tgattacaag atgtagtcag attttggtaa cttctaaaac taacttccag
     2761 tttcccacaa cctagctttt agtatgagaa aaacgcgtga catcagtgga aatccgtctt
     2821 agactaactt ccactggttt tctttttctt gatatataag ggttcaaaag cgaaaagact
     2881 cagaaaaagt gcacgacaaa tagccctaaa acagagtcgt cttagagtaa cttccagttt
     2941 tgggagagag atggaagtta ctttgagaag ttacggtagt cagatttttt tagaaaaaca
     3001 ttttataaat attcacatat ctcctatatt tatggtaaaa tagaattatc agtttatttt
     3061 ggagtcaaag atgaatatat ttagaacaaa gaatgttagt ttagataaaa cagagatgca
     3121 taggcatttg aagttatggg atttgatttt gctgggtatc ggagccatgg tagggacagg
     3181 cgtctttaca atcacaggta ctgcagctgc aacacttgct ggcccagccc tagtgatttc
     3241 aatcgttatt tctgccttgt gtgtgggatt atcagccctc ttttttgcag aatttgcctc
     3301 gcgagtaccc gctacaggag gtgcctatag ttacctctat gctatcttag gagaattccc
     3361 tgcctggttg gctggttggt taaccatgat ggagttcatg acagccatat caggcgtagc
     3421 ttcgggttgg gcagcttatt ttaaaggctt gctctctcaa tacgggatag cctttcctca
     3481 ggctttaaat ggtaccttta atcctcaagc agggacattt gttgatttat tgcctattct
     3541 tgtcttggtc ttggtgactt cgcttgtttt actaaatgcc aaggcagcct tacgctttaa
     3601 ttcgattcta gttattttga aattttccgc tttagctctc tttgttttag taggaatttg
     3661 gaatattaag tttgataatt ggagcaattt tgctccttac ggttttggac aaatctatgg
     3721 agctagtact ggtattatgg ctggtgcatc cttgatgttc ttcggttttt tgggatttga
     3781 atccatctct atggctgtag atgaagtcaa gactcctcaa aaaaatattc ctagagggat
     3841 tgtcttatcg ctttctatcg taaccattct ctatgccttg gtgacccttg ttttgactgg
     3901 tgtggttcac tatagtcatt taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt
     3961 tgggattagt tgggcagcca actatgtgtc attagtggct atcttgacct tgattacagt
     4021 ttgtatttcg atgacctatg ccctatcgcg tatgatttac agtttagcac gtgacggctt
     4081 agtgcctgct gcctttaagg aactgacgaa gactagcaag gtaccaaaga atgctactat
     4141 cttgacaggt ctagcttcag cagtagcagc aggaatgttc ccactagcca gtattgcagc
     4201 ctttttaaat atttgtacct tagcctactt gatcatgttg gcttatggtc tgattcgctt
     4261 acggaaagaa aaaggaatgc ccaaagctgg ggaatttaaa acaccattgg tacctctgtt
     4321 accaatttta tcgatcatca tttgtttatc cttcatgtta cagtataata tgaatacctg
     4381 gattgctttc ctagttgcgt tgttagtagg aagtattatt tacttcactt atggctataa
     4441 gcattctacc atagaagaat aaagtgaaag tctattgagt tgttgacact cagcagattt
     4501 ttatatgtga aagaaatttc aaattttttc taaaaatatc ttgacagatt aaattttcag
     4561 gagtagaata tttactagtt aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt
     4621 tatttttagt cctgttaagt gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa
     4681 gtcagacagg aaaggggatg aaaattgtga ccagttttta tcctatctac gctatggtta
     4741 aggaagtatc tggtgacttg aatgatgttc ggatgattca gtcaagtagt ggtattcact
     4801 cctttgaacc ttcggcaaat gatatcgcag ccatctatga tgcagatgtc tttgtttacc
     4861 attctcatac actcgaatct tgggcaggaa gtctggatcc caatctaaaa aaatccaaag
     4921 tgaaggtctt agaggcttct gagggaatga ccttggaacg tgtccctgga ctagaggatg
     4981 tggaagcagg ggatggagtt gatgaaaaaa cgctctatga ccctcacaca tggctagatc
     5041 ctgaaaaagc tggagaagaa gcccaaatta tcgctgataa actttcagag gtggatagtg
     5101 agcataaaga gacttatcaa aaaaatgcgc aagcctttat caaaaaagct caggaattga
     5161 ctaagaaatt ccaaccaaaa tttgaaaaag cgactcagaa aacatttgta acacaacata
     5221 cagccttttc ttatctagcg aagagatttg ggcttaatca acttggtatt gcaggcatct
     5281 ctcctgaaca agaaccaagt ccacgacaat tagcagaaat tcaggaattt gttaaaacct
     5341 ataaggttaa aacgattttt acagaaagta atgcttcttc aaaagtagct gaaactcttg
     5401 tcaaatcaac aggtgtgggt cttaaaactc tgaatccttt agaggcagac ccacaaaatg
     5461 acaagaccta tttagaaaat ctggaagaaa atatgagtgt tctagcagaa gaattaaagt
     5521 gaggaaagaa tgaaaatcaa taaaaaatat ctagcaggtt cggtggcagt tcttgcccta
     5581 agtgtttgtt cctatgagct tggacgttac caagctggtc aggataagaa agagtctaat
     5641 cgagttgctt atatagatgg tgatcaggct ggtcaaaagg cagaaaactt gacaccagat
     5701 gaagtcagta agagggaggg gatcaacgcc gaacaaatcg tcatcaagat tacggatcaa
     5761 ggttatgtga cctctcatgg agaccattat cattactata atggcaaggt cccttatgat
     5821 gccatcatca gtgaagagct cctcatgaaa gatccgaatt atcagttgaa ggattcagac
     5881 attgtcaatg aaatcaaggg tggttatgtc cttaaggtaa acggtaaata ctatgtttac
     5941 cttaaggatg cagctcatgc ggataatatt cggacaaaag aagagattaa acgtcagaag
     6001 caggaacgca gtcataatca taactcaaga gcagataatg ctgttgctgc agccagagcc
     6061 caaggacgtt atacaacgga tgatgggtat atcttcaatg catctgatat cattgaagat
     6121 acgggcgatg cctatatcgt tcctcacggc gaccattacc attacattcc taagaatgag
     6181 ttatcagcta gcgagttagc tgctgcccaa gcctattgga atgggaagca gggatctcgt
     6241 ccttcttcaa gttctagtta taatgcaaat acagctcaac caagattgtc agagaaccac
     6301 aatctgactg tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta
     6361 cgtgaattgt atgctaaacc cttatcagaa cgccatgtgg aatctgatgg ccttattt
//
LOCUS       DBERAE010000069         6272 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.69, whole genome shotgun sequence.
ACCESSION   DBERAE010000069 DBERAE010000000
VERSION     DBERAE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.69"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..3119
                     /locus_tag="ACL70N_002045"
     CDS             <1..3119
                     /locus_tag="ACL70N_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HGS0590782.1"
                     /translation="VTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNA
                     TKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYR
                     LENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSET
                     GVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTG
                     IKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEAL
                     QRYTREESTRQATAVRELVNRDFVGKVTYQEDVKGINQRIEAVKTSANKDIASQIASY
                     RQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGT
                     DNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRKVETTDFQR
                     VKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFKNATN
                     EWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFN
                     NSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAYIRF
                     DNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLAGSWV
                     VENINSAGDIISGINLGANGHNRLVGKLTHITGETLIDRAVIKSAMVDKLKTANFEAG
                     SVTTTILEAEAVTAEKLKVDDALIRKLTAKDAFIDRLTSKRIFSTKVESVISSSTFLE
                     AYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNNWNYAGPK
                     AWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKDVLGD
                     GWNPKGGRNAVVWWNQVGSGSLKYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFD
                     FIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKI
                     EKMEKTIA"
     gene            3116..3232
                     /locus_tag="ACL70N_002046"
     CDS             3116..3232
                     /locus_tag="ACL70N_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HGS0590783.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTHRLENLENEHRTA"
     gene            3213..3416
                     /locus_tag="ACL70N_002047"
     CDS             3213..3416
                     /locus_tag="ACL70N_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590784.1"
                     /translation="MNTEQLNQALRMTISEISTTSTNSMITSNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            3419..3769
                     /locus_tag="ACL70N_002048"
     CDS             3419..3769
                     /locus_tag="ACL70N_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590785.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTGEPKE"
     gene            3779..4195
                     /locus_tag="ACL70N_002049"
     CDS             3779..4195
                     /locus_tag="ACL70N_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGS0590786.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4199..4531
                     /locus_tag="ACL70N_002050"
     CDS             4199..4531
                     /locus_tag="ACL70N_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGS0590787.1"
                     /translation="MQQITEIIIAFATSFLTVAVGGIVKAVKDYLLRKGGEKAVIIAE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4535..5491
                     /locus_tag="ACL70N_002051"
     CDS             4535..5491
                     /locus_tag="ACL70N_002051"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGS0590788.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNTFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5629..5808)
                     /locus_tag="ACL70N_002052"
     CDS             complement(5629..5808)
                     /locus_tag="ACL70N_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590789.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(5950..6099)
                     /locus_tag="ACL70N_002053"
     CDS             complement(5950..6099)
                     /locus_tag="ACL70N_002053"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590790.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
BASE COUNT         2018 a         1159 c         1423 g         1672 t
ORIGIN      
        1 atgtgactgc tgaaaatatc cggcaatctg tgaagagtct tgagacagac acgcagaaca
       61 aactaaatca gaagttgagt caggctgaat ttgaggtgcg agctggctct atccgtcagg
      121 aaatcctgaa cgcaaccaag gacaaggcag ataagacttt agttgtatct gaagccggga
      181 aattgcgtga agaattttca aaaatgaagg tgggaggccg gaatctatgg ataaaatcca
      241 agacggttgg agctgtaatt gaaaaattac ctgaaaacca cgtcacaggt caaaaagaat
      301 gctataggct agagaacaac tctactttaa cgttcaacct tgaaccagat ttcagctcaa
      361 ggttgtatca aaaagttact tttagcgctt ggatcaagta cgaaaatgta gtccaaggtc
      421 gaaatttttg gaatgtattt aattgcttca aacattatct ttttagaaaa aatagtgaga
      481 ccggagtaca gagtggtcca gattatgcta cgcttggtat gtataaaggt tcggcagatt
      541 ggaaatatat tacattcact tatgactact ctgaaaaaac aaattttgat caattgaaga
      601 catcattgcg attcaatctt gaaggtgcta caagcggtac agcttgggta acaggaatca
      661 aggttgaaat cggtagtgtg gcgacggatt ggagccctgc gcctgaggac gctgatggtc
      721 tcatcactga ggctaaggct acctttgagc ggacagctca gggcttgcga accgacttat
      781 cagctattca ggaatatgta aataaagacg gtcagcgaca ggaagcccta cagcgctata
      841 ctcgtgagga gagcacgaga caagcgacag cagtccgtga gctggtcaat cgtgatttcg
      901 ttggtaaggt tacttatcaa gaagatgtta agggtatcaa tcagaggatt gaagctgtta
      961 aaactagtgc gaataaagac atcgctagtc aaatcgctag ctatcgtcaa tctgtagatg
     1021 gtaagttcac ggatatttca agtcagataa ctacttataa gcaagatgtg ggcggtcaaa
     1081 tcagtggcct ttcaaataga cttacaagca gtgaacaagg aaccactact cagatttcaa
     1141 atctttcaaa tcggataaac agtaacaaac aaggcacaga taatcagatt tcaaatttaa
     1201 agactcaggt cgctacaaac aaggataatg ctgaacgaca aatgggtaga atatctgatc
     1261 aggtttctgc aaacaaagcg aatgctgata gtcaatttgc gaatgtgacc aatcaactag
     1321 tgcgaaaagt agagactact gacttccagc gtgttaagga aaccagtaaa ctttacgagc
     1381 ggattttggg caatactgaa aatggaattg cggataaggt tgctcgcatg gctctgacca
     1441 atcaactatt tcaggttgag gttgggaaat atagtgtaag cggccctaac ctcattaaga
     1501 atagtgattt taaaaatgct acgaatgaat ggggctcaac tcaaaattta ggaagattgg
     1561 ttaagcatag cttttatcac aacgggcaga aagaccttat gcgtttaagt aatgcaacta
     1621 aaaacgaaaa ctttttgtat agtcaccgtt ttaatcttga acgaaatact gactatgtac
     1681 tgaattttag aggatttaac aacagtgctc tagcaagcta tgatgtttat attttgggac
     1741 gaagagcagg cgagagcgat ggattcacaa tcgttaagaa agttgttagc agcaagaaac
     1801 tatctacctc tagatgcgaa gatgtctcag taacttttaa ttccggagaa atggataatg
     1861 cttacattcg ttttgataac aatggctcat catcaggaac agctgatttg tatattacag
     1921 aagttgactt gtacaaaggt tataaaccta gaacatggca accacatcca gaagatgcag
     1981 tcgcagatgc gaataagaag cttgaagcaa cgcaaacaaa aatgactcaa ctagctggct
     2041 catgggtagt tgaaaacatc aactcggctg gagatatcat ctctggaatc aatcttggcg
     2101 ccaatggaca taaccgctta gttgggaaat tgacccacat cactggagag accctgattg
     2161 acagagcagt catcaagtct gccatggttg ataagctcaa aacggccaat tttgaagctg
     2221 gttcggtcac gactacgata ttagaagctg aagcggtaac tgctgagaag ttgaaagttg
     2281 acgatgcgct tattagaaaa ttaactgcaa aagatgcttt tattgaccga ctgacatcta
     2341 aacgtatctt ctctactaag gttgagtccg tcatttctag ctcaaccttc ctagaagcct
     2401 atcaaggccg aattggtgga ttcacacttg gtcaatttga ccagggtggc ggtcgctgga
     2461 tttcaggtgt caatcagttc tctgttggta tggggaatgg tgccgggcat ggagtccgga
     2521 cagccttctg ggcgaactgg ggaaataatt ggaactatgc cggacctaaa gcatggaacg
     2581 tcaatactga tgggaaaatg tactgtagga atgaagtcgg tttttatgat caagtggatt
     2641 tttcgaattc atcgagagca aacttctatg ggaatactac tttttctcgt tctcctgtgt
     2701 tttcaaatgg tatcgaactt ggaagtaaag atgtgcttgg tgatggttgg aatcccaaag
     2761 gcggaaggaa tgcggttgtt tggtggaatc aggtcggtag cggtagcttg aagtattgga
     2821 tggaacaaaa atcagataga cgcttaaaag agaacatcac agatacagct gtgaaagcct
     2881 tggacaaaat caacagatta agaatggttg catttgattt catcgaaaat aagaaacatg
     2941 aggagattgg tctaatagct caagaggctg aaaccatcgt tccaagaatt gtctcacgag
     3001 atcctgagaa tccagatggc tatctacata tcgactatac cgctttagtt ccttacttaa
     3061 tcaaggctat tcaagaatta aatcaaaaaa tagaaaaaat ggagaaaaca atagcatgaa
     3121 taacaacatg ttgaccaata tcgcacttaa agcaattcag gagcttgctc ttgaaaatag
     3181 aaaacgaaca cacagattgg agaacttaga aaatgaacac agaacagctt aaccaagcct
     3241 tacgaatgac aattagtgaa atatcaacaa cttcaacaaa ttcgatgatt acaagtaata
     3301 tcttgagtat tcagttggat gagcaaaggg aagaaaatca aagacttcaa gcacgagtgg
     3361 atgagctgga agctctgctt gatgaacaaa ctaaaccagc agacaaagga gaatagacat
     3421 ggcagaaaca attcaaaaca cagataactt actagacctt acaaaaatca cagaaccatt
     3481 tgatcttgcg agtgctttgc gctacatgaa agaaaatgga gagttcattc gttgcaagaa
     3541 tgtaagcgat gacttctata tgtatcgtga tgttcaaaaa cgtcctgtga tcgtaaatgg
     3601 ccgtcgccaa ctcaaggatg ttgaaaccgt ttgggcgttc aaccagtggg gtggtacaat
     3661 cgcaacaatc aacgtcgccg ttctgttgaa tcatgaattc tatatcatga aatttgatgc
     3721 agagggcaat cctgactgga cggatccaac gggagaacct aaagaatagg agatgtgtat
     3781 gcaaattgaa tttttcaatt ttctaagaag tgtcgtacag actgaagatg gtttggtctt
     3841 gtacgctcta gcactgattg tctcaatgga aatcattgat tttgtgacag ggacgattgc
     3901 ggcgattatc aatcctgaca tcgagtacaa gagcaaaatc ggcattaacg ggctccttcg
     3961 taagatttca ggggttctct tactgatgat cctcattccg gcgtccgttt tgttgcctga
     4021 aaagacaggt tttgtattct tgcactcaat ctatctcggg tacatcgcat ttacttttca
     4081 atctctcatt gaaaattatc gcaaattaaa aggaaatgtt actctttttc agccgattgt
     4141 aaaagtattt cagcgattac ttgaaaaaga tgatgacacg aaaaaaggag aataacaaat
     4201 gcagcaaatt actgaaatca tcattgcttt tgcgacaagc tttttaacag tagcagtagg
     4261 cggtattgta aaagcagtaa aagattatct tttgcgtaaa ggcggagaga aagcggtgat
     4321 catcgctgaa attctagcta aaaatgcagt aaatgccgtg gagcaggtag ctgctgaaac
     4381 tggctacaag ggagatgaaa aactggcaca ggctcgcgct aaagtccgtg ctgagcttac
     4441 aaaatacaat attagcatga ctgacaaaga cttagacacc ttcgtagagt cagcagtgaa
     4501 gcagatgaat gacgcatgga aaggacgata gggaatggat atcgatagaa acagactacg
     4561 tacaggcttg ccccaggttg gggtgcagcc ttatcgacaa gtacatgctc actcaacagg
     4621 taaccgcaac tcaaccgtac agaatgaagc ggattatcac tatagaaagg accctgaact
     4681 agggttcttt tcacatgttg tcggaaacgg ccgtgtcatg caagtaggtc ctgtgaacaa
     4741 cggaagttgg gatgttgggg gcggttggaa tactgagagt tacgcagcgg ttgaactgat
     4801 tgaaagccat tcaactaagg aagagtttat ggctgactac cgcctctata tcgaattgct
     4861 acgcaatcta gcggacgaag caggcttgcc gaagactctt gatacagacg acttggcagg
     4921 tatcaagacg catgaatact gtaccaataa ccaaccaaac aaccactcag accatgtgga
     4981 tccatatcca tatcttgcaa gttggggcat tagccgtgaa cagtttaagc aagacatcga
     5041 aaacggcttg agagctgcaa caggctggca gaaaaatggc actggctact ggtacgtaca
     5101 ctcagacggc tcttatccaa aagataagtt tgagaaaatc aacggtacct ggtattattt
     5161 cgatggctca ggctatatgc tttcagaccg ctggaagaag cacacagacg gtaattggta
     5221 ctactttgac caatcaggcg aaatggctac aggctggaag aaaatcgctg agaagtggta
     5281 ctattttgat gtagaaggtg ccatgaagac aggctgggtc aagtacaagg acacttggta
     5341 ctacttagac gctaaagaag gcgccatggt atcaaatacc tttatccagt cagcggacgg
     5401 aacaggctgg tactacctca aaccagacgg aacactggca gacaagccag agttcacagt
     5461 agagccagat ggcttgatta cagttaaata aatagaaagg aaactttcta aattgttctt
     5521 tcaccgcagg cttaggcttg cggtttttta tttgctctga ttctttaaaa aagcgttttc
     5581 ttgaagaata gagaggtgtt ttgtcaaaaa taaaaacagt gaccgaaatc actgcttatc
     5641 agttgtagca aattcataaa gtttttctgc tgtgagaagt gccattttgt ccatgcttgt
     5701 ttttcctttt ctgaggtcag aaacagtagt ccatggaact ccagcacctt gggaaatagc
     5761 agatgtagac atcgaactgt ctaacaattc ttgaataact tctctcatct tatttgtcct
     5821 ttttattttt tagataaata tatacattga ttgcaattat aaaaatagct attgcactaa
     5881 ccattgcatt tcctctttcc atttgataaa atagaggtgt aaggggcttt cgccccaacc
     5941 tcttagcgtt tacctttttc tttgacggga tttcggttta cgctttttgt tttgccttgc
     6001 gaccgttatt gcggtcacta gacttgcgat agcagttacc gtttcaggaa tattgtctat
     6061 tgccttttca agtaacctga gccaatcttc tttgttcaac ttcatcaccc cctttcctta
     6121 tcttgattat attatatcac ggtacaccga gaaagtcaag cgttttgatg aagttttttt
     6181 aattttttca aaaaaaaata gaccttgtcc agaggtcggg gagttggagg gggcaccctc
     6241 caaaagcatt gatttaataa ggttttattt ta
//
LOCUS       DBERAE010000070         6252 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.70, whole genome shotgun sequence.
ACCESSION   DBERAE010000070 DBERAE010000000
VERSION     DBERAE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.70"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            168..854
                     /locus_tag="ACL70N_002054"
     CDS             168..854
                     /locus_tag="ACL70N_002054"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS0590791.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="ACL70N_002055"
     CDS             855..1787
                     /locus_tag="ACL70N_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590792.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="ACL70N_002056"
     CDS             1798..2727
                     /locus_tag="ACL70N_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0590793.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="ACL70N_002057"
     CDS             2741..4180
                     /locus_tag="ACL70N_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590794.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="ACL70N_002058"
     CDS             4249..5826
                     /locus_tag="ACL70N_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0590795.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..>6252
                     /locus_tag="ACL70N_002059"
     CDS             5886..>6252
                     /locus_tag="ACL70N_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGS0590796.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLN"
BASE COUNT         2120 a          858 c         1198 g         2076 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gactttttat
     1141 tctctttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgagaaa tttagttgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accacgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gattttggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aatcatttga ttggcagcca cttgtttatc caaaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa ta
//
LOCUS       DBERAE010000071         6152 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.71, whole genome shotgun sequence.
ACCESSION   DBERAE010000071 DBERAE010000000
VERSION     DBERAE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.71"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..82)
                     /locus_tag="ACL70N_002060"
     CDS             complement(<1..82)
                     /locus_tag="ACL70N_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0590797.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNK"
     gene            291..2060
                     /locus_tag="ACL70N_002061"
     CDS             291..2060
                     /locus_tag="ACL70N_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGS0590798.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     VAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            2084..4039
                     /locus_tag="ACL70N_002062"
     CDS             2084..4039
                     /locus_tag="ACL70N_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0590799.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            4041..4478
                     /locus_tag="ACL70N_002063"
     CDS             4041..4478
                     /locus_tag="ACL70N_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0590800.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4540..5676
                     /locus_tag="ACL70N_002064"
     CDS             4540..5676
                     /locus_tag="ACL70N_002064"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGS0590801.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1874 a         1029 c         1252 g         1997 t
ORIGIN      
        1 atttatttga aagcttctct aagctatatc cttgttttct aagttcatag atctgaactt
       61 tatcatcata agttaatttc ataataaaaa caccccaaaa gttagatttt ttctgtctaa
      121 cttttggggt gtagttcatg tacacctgat atgatgcgtt ttataatttt taagcctttt
      181 tgcccagcct cgtcaaaagt aatgttttga cacaaaatct gtgacaaaac tttagtttta
      241 aaggttttta actttgtata tactagtttt aagaaaagga ggatgatcta atggaagaaa
      301 aagtatcatt gaaggtcagg gttcaaaaac tagggacatc gctttcaaat atggttatgc
      361 ccaatattgg agcatttatt gcttggggag tattgactgc cctctttatc gctgatggct
      421 atctgccaaa tgaacagtta gctactgttg ttggtcctat gttaacgtat ttattgccaa
      481 tcctgattgg ttacacaggt ggatatatga tccatggcca acgtggtgcc gttgtaggag
      541 ctattgctac tgttggtgca atcacaggtt ctagtgttcc tatgtttatc ggagctatgg
      601 taatgggccc actgggagga tggactatca agaaatttga tgagaagttc caggaaaaaa
      661 ttcgtcccgg atttgaaatg ttagttaata acttctcagc tggtctcgtt ggttttgcat
      721 tattgctttt ggctttctac gcaatcggtc cagtcgtatc gactcttact gtagctgttg
      781 ggaatggtgt tgaggctatt gtcaatgctc gcctccttcc tatggctaat attatcatcg
      841 aaccggctaa agtccttttt ctcaataatg ccctcaatca tggcattttt actcctctgg
      901 gagtagaaca ggtagctcaa gctggtaagt caattctctt cctattggaa gctaatcctg
      961 gaccaggcct gggaattcta ttagcttatg ctgtattcgg taaaggttct gctaaatctt
     1021 cttcttgggg ggcaatggtt attcatttct tcggagggat tcatgaaatt tactttcctt
     1081 atgttatgat gaagcctact ctatttttag ctgctatggc aggaggtatc tctggaactt
     1141 ttacttttca actcttagac gctggtctta aatctccagc ttcaccaggt tctattattg
     1201 cgattatggc tacggcgcca aaaggtgttt ggcctcatct aaatgttctt ttaggtgttt
     1261 tagtggcagc agttgtttct ttccttgtag cagcccttat tcttcatgca gacaagtcaa
     1321 ctgaggattc gctcgaagct gctcaggcgg ctacccaagc agctaaggct cagtctaaag
     1381 gtcagttagt atcaacttct gttgatgcag ttgtttcgac agactcagtg gaaaaaatca
     1441 ttttcgcctg cgatgctggt atgggaagct ctgctatggg agctagtatt cttcgagata
     1501 aggttaaaaa agcaggtcta gagattccag tatctaatca ggcaatctca aatttgcttg
     1561 atacaccaaa aacattaatt gttactcagg aagaactgac accaagagct aaagacaaga
     1621 gtccaagtgc tattcatgtt tctgttgata atttcttagc gtcccctcgt tatgatgaaa
     1681 ttgtagcttc attaacagga gcttttccaa tagcagaaat tgaaggagat ataccaactt
     1741 cagcaccagt agatagtcag gaaattgacc ttaaccatat tgatgctgta gtagttgctt
     1801 atggtaaagc acagggaact gcaactatgg gctgtgaaac gattcgggct atctttagaa
     1861 acaagaatat tcgtattcca gtttctactg ccaaaatttc agaattaggt gaatttaatt
     1921 ctaaaaacat aatgattgta acaactattt ctttacaggc agaagtgcag caagcagcac
     1981 cgaattctca atttcttatt gtggatagtt tagtaacaac accagaatat gacaaaatgg
     2041 ctgctagaat gtacaaatag aactagaggt ttctaaatta cgaatgctat taaccaaacg
     2101 agaagaacaa ttattgaagg ctttcctaca tgtagggaag ctttcaatgc aagatatgac
     2161 tgaaatctta caggtttcat ctagaacaat ttatcgaact ttatcagatt tgacagatag
     2221 catggagcaa tatggaatcg aaataacgaa gcatgggaaa tactatattt tgactggaga
     2281 gttggatgat ttgccgacag aacttgaagt gttagttgag tatagtcccc aagaaagaca
     2341 agagttgatt acctatcgcc ttctgactga gagcggtttt gtcaccaatg aagcattgca
     2401 agagtgcacg aaagtcagta atgtaactat tattcaggat atttcagata ttgataagcg
     2461 tcttttagac tttgatctga aaattgaacg acaaaaaggt tatcggattt ctggtgattc
     2521 agttggtaag agaagatttt tggctatttt actgacaaac tgtatctcag tagcagattt
     2581 ttcaaccggt aattttggga gctttgatat tttagaagca gatagaacta ggctggccag
     2641 tcagattgtt aataagcaac tgtcaggttt tccagatatg gatgctagga tgaagatgtt
     2701 ttttgcgatc ttgttatctc ttataggtca ggagcaaaac attgaaaatt cacctaatac
     2761 tagtaagcag gctttggaaa tttctcaaaa aatttttcaa gcttactcta agcagactgc
     2821 acaattttat agtattcagg aaattatcta ttttgcgagc atcttggatg aattaatcat
     2881 taaacgtcag gacaatccgc tctttacgga gaaatttgat ggtgaatttt tctacaatat
     2941 ttcaaatctg attgatacgg tttccatgta taccaagatt gactttttta aggacaaggt
     3001 tttattcaat tttcttttcc atcatattcg gctcagttta ggcgtcccta tcctttttca
     3061 gggtgaaaat ttgccagaat ctatccagat tttagttgaa aggaataaat ttctttatac
     3121 agtcatcagt cttttagtga atgatatttt tccgaaatat cttcatacag agtatgagta
     3181 tggcatgatt gccctacatt ttatctctag cttaggccgt agtccagaga tttatccagt
     3241 ccgtgttttg cttttaacgg atgaacgtcg ggtcactaga gatttattag tcagtaaaat
     3301 taagagtgtt gctccttttg tagagttgat agatattcag tctctagtag attaccacag
     3361 tattgatctc agtcagtatg attatatttt atctaccaag ccgctgacta atcaggaaat
     3421 cgatgtaatt tctagttttc caaccgtcaa agaattgctt gaattacagg aacgacttca
     3481 gtatgtacag gcacatcgta caattgtcgc gcgtgatgct atcgctccag agaaaagtta
     3541 tgacttgcaa gattatttaa tatctagtag tcagcttttg agtcaatttg agttggttca
     3601 attggagaat aatcaatcat ttgagcacac ggtagaacaa atcatccaat atcagaagaa
     3661 tgtgagtgac agagattacc taacaagaaa attgttatct cacttccaga atagtcctat
     3721 ggctattcct aatactggtc tggtgctttt acatagtcag tctagcaaag taacaacaaa
     3781 tagttttact atgtttgaac tcaaactacc tatctccgca ttgtcaatga aacgagagga
     3841 agaagaggtc aaaaggtgtc tgctaatgct aatgtctaaa gaagctagcg aggaagcgag
     3901 agatttaatg acagctatta gtcagtcgat tattgaaaat catctttata cagagattta
     3961 caagacggga aatcaatcca ttatttatca gatgctaaat actattttta acgaaaaaat
     4021 taagaaattg gagaactaat atgaaacttg aaaaacattt gattaagctt aataaacaat
     4081 tttctaacaa ggaggaagct atttgttatt gtgggcaagt tctttatgag ggtggatatg
     4141 ttaatgaaga ctatattgaa gccatgattg agcgagataa agagctatct gtttacatgg
     4201 gtaactttat cgccataccg catggaacag atgcagcaaa aaaggatgta ctcaagtctg
     4261 gtattacagt cgttcaagtc cctagagggg ttgattttgg gaatgtatct aaccctcaag
     4321 tggcaacggt tctttttggt attgctggta ttggtaatga acacttggaa attattcaga
     4381 aaatttctat cttctgtgca gatgtagata atgttcttaa actagcagat gctcagtcaa
     4441 aagaggaagt attgcgctta tttgatgctg ttgaataatt gaatttcgtc atttgtcatc
     4501 tagtatatat gtccctcaaa taggaaaagg agaaattgaa tgaaacattc tgttcatttt
     4561 ggtgccggta atatcggtcg tggttttata ggtgaaattc tatttaaaaa tggtttccat
     4621 attgattttg tggatgtcaa taatcagata attcatgctc taaatgaaaa gggcaagtat
     4681 gaaattgaaa ttgcacagaa aggacagtct cgtatagaag taactaatgt ggctggcatt
     4741 aatagcaaag aacatcctga gcaagtcatt gaagcgattc aaaagacgga tattattact
     4801 actgcaatcg gacctaatat actccctttt atcgccgaac ttctagccaa aggaatcgaa
     4861 gctcgccgag ttgcaggaaa tacacaggca ttggatgtta tggcctgtga aaatatgatt
     4921 ggcgggtctc aatttcttta tcaagaagtc aagaaatatt taagtccgga aggtttgaca
     4981 tttgctgata actacatagg ttttccaaat gctgcagtag acaggattgt tccagcacaa
     5041 agtcacgaag attccctttt tgttgtggtc gagcccttta atgaatgggt cgtggaaacc
     5101 aagcgtctta aaaatccaga tttacgtcta aaagatgtgc attatgaaga agatttagaa
     5161 ccctttattg agcgaaaact tttttcagtc aattctggac atgcaacttc agcttacatt
     5221 ggtgcgcatt atggtgccaa gacaattttg gaagctcttc aaaatcctaa tattaaatct
     5281 cggattgaat ctgtattagc tgaaattcgg agtctcttga ttgccaaatg gaactttgat
     5341 aaaaaagaat tggagaatta tcacaaagtc attatagaac ggtttgaaaa ccctttcata
     5401 gtggacgagg ttagtcgcgt agctcgtact ccaatccgaa aattaggcta taatgaacga
     5461 ttcatccggc cgatacgtga attgaaagaa ctcagtttgt catataaaaa cctacttaaa
     5521 acagttggct atgcctttga ctatcgcgat gtaaatgatg aagaaagtat tcgattaggt
     5581 gaattgttgg ctaaacaatc agtcaaagat gttgttatac aagttacagg tttagacgac
     5641 caagaattga ttgagcaaat tgtagagtat atttaatctt tttcgaaaat ctcttcaaat
     5701 caggttagca tcgctttgtc ttaggcatat gttgttctat ctacaacctc aaagcagtgc
     5761 tttgagctga ctccgtcagt cttgtctgca acctcaaaac actgtttgag ttatctgcgg
     5821 taatctttct agcttgtctt tgatttttgt tgttatttat aaggtaaaag aagctggaca
     5881 aaaagtcttc aaaatcggaa aaaggcagcc tatcgggtgt tcaaaaatct tgataggatg
     5941 tcctttatta tggaaagcct tattggattt tctcctcaga ttgagttttt gatcagcttt
     6001 atgagatagg ttttgctaga gatgtagccc atcatgttat ttttatggac ggtgggaaaa
     6061 ttgttgaaaa aaataatgcc catcaattct ttagtcgtcc aagagaagaa cgaaccaagc
     6121 aattttggaa cgaattcttt cgaatgcgat ct
//
LOCUS       DBERAE010000072         5379 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.72, whole genome shotgun sequence.
ACCESSION   DBERAE010000072 DBERAE010000000
VERSION     DBERAE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.72"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1138)
                     /locus_tag="ACL70N_002065"
     CDS             complement(<1..1138)
                     /locus_tag="ACL70N_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0590802.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYAINGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTHNLINSKFSSK
                     DIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLL"
     gene            1500..1856
                     /locus_tag="ACL70N_002066"
     CDS             1500..1856
                     /locus_tag="ACL70N_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGS0590803.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            1861..2226
                     /locus_tag="ACL70N_002067"
     CDS             1861..2226
                     /locus_tag="ACL70N_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGS0590804.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLIPGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            2213..4036
                     /locus_tag="ACL70N_002068"
     CDS             2213..4036
                     /locus_tag="ACL70N_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="HGS0590805.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            4150..5016
                     /locus_tag="ACL70N_002069"
     CDS             4150..5016
                     /locus_tag="ACL70N_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0590806.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
BASE COUNT         1887 a          782 c         1022 g         1688 t
ORIGIN      
        1 tcaataacct aactaagttt aattcagtta gatttacttg attttcttgg atgctataat
       61 caggattttt atgtctagct tttttatagt aaaaatcgaa atctttttct gtaacttcaa
      121 gttgattcac tatgtctttt gatgagaatt tactatttat caagttgtga gtctttttca
      181 attctaattt tgtgtcataa attactatac tatttttaaa tctagttaaa ggatattttt
      241 cgagaccagg tattgaagaa aatactttca gcaattggta ctttaaagta tttttgtata
      301 agcagtgata ataaatagtc tcctgataat ctattttaaa actttctact tcaggggaag
      361 ggactagaca attaccttga tctaaataca tagccataca ctcgtcaatt gtaagatgac
      421 gatatcgaag ttgtactaat tgccaatcaa tattagtctg gtattgattt aaactataag
      481 acatagtttt gaaacgattt gcatcatcgt cgttaagttt aatataaaaa tcgggattag
      541 gattataaat aaaaaatctt ccgtcttcat tttcaatgaa gaaccaattt ttatagtctt
      601 ttaaaacatg aaaatactgc tctttgatat ttaagtcggt atgattaaac ttttgaaaca
      661 actcatttat taactcaaaa ggagcagagg agtctttagg ggtatttata gagccattta
      721 tagcatatat taatcctttt ggtaatgcag tatctttctt aggcttataa tcttttgtta
      781 aaaatacagg aactttatct gtatcatgaa taattaagat gtcaatttct ttgttgtcta
      841 tagtttcagt ttgtatgcta attttaattt gattatttgt tgatataaag agtttatgta
      901 gtaaatctgt tagatcttct tcatttcttc tattatcatc attgtttaca ccgattatat
      961 ctaaagtgat attatcaatt ccaaagatga tataacaatc ttcgtgatgt gatgtattga
     1021 caaaatttaa gatatcacgc accaattcag tttttgaatg atgccatttt tgtttaaaat
     1081 catgaaactc atcttcgggt gtattcaata gtaagtgtat ttgatctaga ctcagcattt
     1141 ttatttctcc aaatattagt ttacagaaat tttatcatag aatcagagaa agtcaatcat
     1201 aactatatta gctgtgatac ctttttcaaa tcttccctgt tatcctaata tcattcatag
     1261 aaaatcaatt tttgattttc tatgggggtt tgggggcgaa gtcaccaagt tatcttatcg
     1321 ttggctgtca aaactagaaa gttttgatag gctggcgata tgatttttga gatattgtgg
     1381 acacaatatc tgagctcgca aagccttaca agaatgaaaa tcagttgttg gaaaagtgta
     1441 ctgacattgt atggtagctc acattgtcag tacaagtatt ttggaaagga agtagcagta
     1501 tgaaacgaga tgtgcgtgat attcggaaac aatttcgttt aacagaagca gaagaaaagc
     1561 aaattctagc tttgatgaga gagcggggag agactaattt ctctgatttt cttcgtaaaa
     1621 gtttactttc ctctgattta caaaaacaga tggagacatg gtttgccctc tggcaatccc
     1681 aaaaactaga acaaatcagt cgtgacgttc atgaagtttt aatcttggca cagtcagaac
     1741 gtcaagtcac ccaagagcat gtatctattc tcttaacgtg cgtgcaggaa ttgattcaag
     1801 aggttgcaaa caccataccc ctcagtaaag aatttcgtga gaagtacatg aggtaagcac
     1861 atggaacatc gttaccgaac caatctcaag aaagtgtttt tgtctgatag tgagttgaac
     1921 caactaaata taaatatcga tcaaagtggt tgtaaatcct tttctgaata tgcgagacga
     1981 actctactcg atcctggtat gaattttatc acgattgaca caaacggtta ccaagattta
     2041 gtgtttgagt taaagaggat tggcaataat atcaaccaga ttgctcgaag tgttaatcaa
     2101 tctcagttaa ttcctggtga agaattgcag gagttgaaaa aaggaattgg tgaattgata
     2161 aaagaagttg ataaggaatt taatctgcaa gcgcagaagc taaaggagtt ccatggtcat
     2221 cactaaacac tttgccattc acggaaagag ttaccgcaga aagcttatca agtacattct
     2281 caatcctgag aaaaccaata atcttgcctt ggtgtcggac tatggcatga agaattttct
     2341 ggactttcct agctatgagg aaatggtgca gatgtatcat gaaaatttca tcagcaacga
     2401 tacgctttac gattttcgcc acgacaggat ggaagaaaat caacgaaaaa tacacgctca
     2461 ccacatcatt cagtctttct cgccagagga tcatctcact cctgaacaaa tcaatcggat
     2521 aggttatgag actgtgaagg aattaactgg tggcaaattt cgttttatcg ttgcgaccca
     2581 tgttgataaa gaccacctgc acaatcacat cattatcaat tcagtagata gcaattctga
     2641 caaaaagctc aagtgggact acaaggtgga gcgaaatctt cgcatgattt ctgaccgttt
     2701 ttctaaaatc gcaggtgcta aaatcattga gaaccgctat tctcaccagc ggtatgaagt
     2761 ctatcgtaag actaatcaca agtatgaact caagcagcga ctctattttt tgatggaaca
     2821 ttctagggac tttgaggatt tcaaaaagaa tgctccgcta ctacatgtgg agatggattt
     2881 ccgtcacaag catgccacct tttttattac ggactcaact atgaaacagg tggtgcgtgg
     2941 caagcaactc aatcgcaagc agccttacac agaagaattt tttaagaact actttgccaa
     3001 aagagaaata gaaagtctca tggaattttt attgctgaaa gttgagaata tggatgattt
     3061 acttcagaaa gcaaaacttt ttggactaac tatcaatcct aaacaaaagc atgtttcttt
     3121 tcaatttgca ggagtggagg taaaggagac agagctagac cagaaaaatc tttatgatgt
     3181 agagtttttc caagattatt ttaaaaatag aaaagattgg caagctccag aaactgagga
     3241 tttcgttcaa ctttatcaag aagaaaagtt atccaaagaa aaagaacttc caagcgatga
     3301 gaagttctgg gagtcctatc aagagttcaa gagtaacaga gatgccgttc atgaatttga
     3361 ggtggagttg tcactcaatc aaattgaaaa agtagtggat gatggaattt acgtcaaggt
     3421 caagtttggt attcgtcagg agggacttat ctttgtgccg aacatgcagc ttgatatgga
     3481 agaggataag gtgaaggttt tcatcaggga aaccagctcc tactatgtct accacaaaga
     3541 cgctgccgag aaaaattgtt atatgaaagg tcgaacctta attagacagt tcagctatga
     3601 aaatcaaacc attccattac gcagaaaagc gacagtcgat atgattaaag agaagattgc
     3661 ggaagtggat gctttgattg aactggaagt agaaaatcaa tcttatgtca cgattaaaga
     3721 tgagttagtg catgaactag cagcgtctga attaagaatc aatgagttgc aagaacgaat
     3781 gtcaaccttg aatcaagtag cagaatatct actggcttca gttgaaagta agcaagaaat
     3841 gaaattaaat ctttcaaaac tgaatataac tgagaatatc agtgctaata ttgttgagaa
     3901 aaaattgaag agcctgggga atcaactgga attggaaagg ggcaggtatg aaaagatggt
     3961 agtcaggcta gataaattta taaatcgctt aaatacagga ctttcaaaag gagatgggat
     4021 agattttcaa aaataggaat ctagccaata attatataca atgtgtatct tttgtaaaat
     4081 atatttgaaa tttagattta atcatgttac aattaacatt gaaatcaaat agaaaaggaa
     4141 gatgcaaacg tgggtacact attagcaaca agattaaaaa atagacgaaa agaattaaaa
     4201 atgtctcagc gagaattagc tgagggtatc tgtaaacagg ggcaaattag tcgattagag
     4261 agtggagagt tcacccctgg agcggatttt ttacatgccc ttgctaagaa attaaaagtt
     4321 agtatggact acttttttga tgagcaggtt gtagaggaag tcaatgagtt atcagagttt
     4381 aagaagttag cacagacatt tatcacaaat cgtaattatg aatctttaaa atatatatat
     4441 gaattggaaa atgtaaaagc ccatcgctta tctctagcag ataaatttta catggaatgg
     4501 ataaagtctc ttatagattt ttatttttat ggacagaaag aagaggcaat tacacgatta
     4561 gagaatatgc tacctcagtt aaatgtatct gatttgaact accttcaagt ttcaaacact
     4621 ctattcaatt tttattatga tattgaagat ttagaacgtt ttaatgagat tagagacaag
     4681 ctagagcatc aagtgaatca gcttaattta aacacaattg aagagttaga actatcaatt
     4741 aagttcaatt ataacgtttg tcgataccta tggttacaga aaaatattga agaagctatt
     4801 acgaaaatca cagctacgat aaagcaatgt aaggagtaca ggacaactta tctattagct
     4861 gatttgtatt tattgatggg aagtgtaagt gaaaattttt cttctaaaag ttcagtaaaa
     4921 gaatattttg agactgctca ttttctctac aaacttgagg aaaacatgtc aatggctttg
     4981 aaagtcgaac attattttgc agatataaca gaataaggaa tacggtgttc tagtgagcat
     5041 cgttttttaa atctaatttg aatacaaaaa agtattaaat aaaaaaaaat aaaaaaagat
     5101 tataaaaata cttgacaagc taattttgaa gtgataaaat aaatgcaaga aaacgaaagg
     5161 agaggtatat gagaagtttg tttaggaaaa ttgttgcttt gttagtcata ggattaatcc
     5221 tattagggac tgctggagga actcaagttc ataagatggc tagagggatt gatcaaggtc
     5281 ctgcgaatgg tatttataga taggagatta tagtcactta aaaatcaaca aattataaaa
     5341 tttttgtttt acttaaatag atattttatg atgggcgaa
//
LOCUS       DBERAE010000073         5329 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.73, whole genome shotgun sequence.
ACCESSION   DBERAE010000073 DBERAE010000000
VERSION     DBERAE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.73"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..803
                     /locus_tag="ACL70N_002070"
     CDS             <1..803
                     /locus_tag="ACL70N_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0590807.1"
                     /translation="LLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCL
                     DIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAP
                     RSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVIL
                     AEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACAR
                     FSPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(1002..2891)
                     /locus_tag="ACL70N_002071"
     CDS             complement(1002..2891)
                     /locus_tag="ACL70N_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGS0590808.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3029..4594
                     /locus_tag="ACL70N_002072"
     CDS             3029..4594
                     /locus_tag="ACL70N_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS0590809.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4594..>5329
                     /locus_tag="ACL70N_002073"
     CDS             4594..>5329
                     /locus_tag="ACL70N_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0590810.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
BASE COUNT         1650 a         1213 c          988 g         1478 t
ORIGIN      
        1 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagacctaa
       61 aaatactggc tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat
      121 acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag
      181 aatataccta ccaactcttg acgcgctacc ctaatcctca gaaaaggatt gaggcaggat
      241 ttgataagct gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag
      301 tcgcacctcg ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaatca
      361 tcaaacatta caagaggctc attgacaagg cggaaacatg tgtcaatgac ttgatggctg
      421 agttcaactc agtcatcacg acggttactg ggattggggg tcgtttaggg gcggtcattt
      481 tagccgagat tcgaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg
      541 gactggattc ttctatttat cagtcaggtc agattgattt agctggaaga atgatcaaac
      601 ggggttcccc tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt
      661 cacctgcttt taaggcctat cttaagacta agttagaaca aggaaaacat tacaatgtag
      721 ccatcatcca ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct
      781 gccatttgac gaacaaaaag tgatgtaatt tctgaaatca acacaggatt acctttgaaa
      841 aaatggactt tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt
      901 gaaataagaa atagtttaga taaaactatt gacttttctt atagtttgtc tttcttctat
      961 cttccattat atcatacttt ttcagtctat ggtagctctc tttaaaaggc tccgatactg
     1021 ccgccacctc cgcctccaga gaagccaccg ccagaacttc cacttccaga agatacggag
     1081 taggtacttg ctgtatttgc gacactagca taatggctca tttgcgcgct tgaatgataa
     1141 aacatactgt gccagccata agctacatag agattgatat ctggattttc aacttgaatc
     1201 tgatgaacct tcatcaaatg actaaccttg tccgcatagc caaataaggt tgcatagacc
     1261 aagagacgat tccaaacaac aatactttcc aattcagcct tatccagtcg tgcaatctca
     1321 cgtaacatat tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga
     1381 acaccatcac gattatctag tcgaagcttc caataataga aaacagacaa aactaaccct
     1441 agaaaaccaa gtattggcaa agggaggtaa agatagccat gaacgtctaa actgtacaag
     1501 aacaaaccaa atccgataaa taggggcaag atagtcaaga cacccatacc cacttgcaaa
     1561 gtcttttcca aaccagttaa aggacgatag taatctggga gcccccagaa ggaaactcgt
     1621 tttctcactc cttcttgcat ctggttcaat acctcttcaa aagaagattt gagttgaagc
     1681 cctcttgctt gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat
     1741 accttgtaat ccgcaaacaa attggaaaga gtggcttctt ttttgcctga aaaggctaga
     1801 tttagacagt ctctctcaaa tcttgacaaa ccatcttctt tcaccaatct caagccaact
     1861 gcatctcctt ctgaaataat agagacattc ccacggtcta tcacatctag caaggtagct
     1921 tgaataagtt gatcaaaggt gaattttcca gctcccttga ccaagggact cacttcctcc
     1981 aaggaggtcg agtagactgc ttctgataaa accataggct ctaattccat tgggggttca
     2041 tagagacgat gatttttagc atatttgact gaaggagtgg tctttcttct ataaataaaa
     2101 tagaagcaga cactcaataa caaggagata gaaagtatcg aagggaggac ccaagtaacg
     2161 agttgtttac tctgatcttt ttctctaaca atcgagtctt ctatcttatt aaactcttct
     2221 aaacgattcc ctttcaatcc ctgatcccta gcgctagcaa aatcggtccg aggccaatag
     2281 gcatgcaact caactccacg cttagccgga agattgtcta aacggatagt atagtcaagg
     2341 ttactctttt caatcgttcc ctctctaaaa agtttccctg tatggaaaaa gagtttttca
     2401 gcccccttgt ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc
     2461 agaggttgcc aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc
     2521 cagacgaggt caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta
     2581 taaccatccg cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc
     2641 gcggcctgaa cctttggatg agggtcaatg tcaaacccgc taggcatctt accagcacgt
     2701 ccaagtccca cgatttgtcc cttaaagtcc tcctcaaact gataaactat cttttgtcta
     2761 aattctgccg tattgtctgc atgaatatac aaatcacctt gataagagtt tatcttaaaa
     2821 tcaatggcga aaacagaaag tggcagaagg caaaacaagc caaacatcag taagaaaaaa
     2881 gtttttttca tcaattaagc ccccttttta tctttcttat cattatagca ttttttcgta
     2941 agtaaaggct tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat
     3001 tttttaatag atcagaatag gagaaatcat gagaaaaata tacttatcta ttttcacaag
     3061 tctcttgctg atgctaggac ttgtcaatgt tgctcaagcc gatgaatatt tacgcatcgg
     3121 gatggaagca gcatatgctc cctttaactg gacccaggat gatgatagca acggagctgt
     3181 caaaatcgat gggaccaatc agtatgccaa cggatacgat gttcaaatcg ccaagaaaat
     3241 cgctaaggac ttaggtaaag aacctttggt tgttaaaacc aagtgggaag gtctagtccc
     3301 tgcccttact tctggtaaga ttgacatgat tatcgcaggt atgagtccaa ctgcagaacg
     3361 caaacaagaa attgcctttt cgagcagtta ctacactagc gaaccagttt tgcttgtcaa
     3421 aaaagattct gcctacgcaa gtgctaaatc tttggatgac tttaacggtg caaaaatcac
     3481 ttctcaacaa ggggtctacc tctacgactt gattgcacaa atcccaggtg ctaaaaaaga
     3541 aacagccatg ggagacttcg ctcaaatgcg acaagctctt gaggctggtg tcattgatgc
     3601 ttatgtttct gaacgtccag aagcactgac tgctgaagct gcgaactcta agttcaagat
     3661 gattcaagta gaacctggtt tcaaaactgg ggaagaagat acagctatcg ctatcgggct
     3721 tcgtaaaaat gacaatcgta ttagccaaat caatgccagc attgaaacca tttcaaagga
     3781 cgaccaagtt gccctgatgg atcgtatgat caaggaacaa cctgccgaag ctacaacaac
     3841 tgaagagact agcagtagtt tctttagcca agtcgctaaa attctttctg aaaactggca
     3901 acaactcttg cgtggtgctg gtatcactct tttaatctct atcgtcggaa ccatcatagg
     3961 tctcattatt ggacttgcca ttggtgtctt ccgtactgct cctctctctg aaaacaaagc
     4021 catttatggc cttcaaaaac tagtcggctg ggttctcaat gtctacattg aaattttccg
     4081 tggtacgcca atgattgttc aatcgatggt tatctactat ggaactgccc aagctttcgg
     4141 gatcaacctt gaccgtacac tggctgctat cttcatcgtt tcaatcaata ccggtgccta
     4201 catgactgaa atcgtccgtg gtggtatcct agcagttgac aagggacaat ttgaagctgc
     4261 gactgctctt ggtatgaccc ataaccagac catgcgtaag attgtcctac ctcaggtagt
     4321 ccgtaacatc ctacctgcaa ctggtaatga atttgtcatc aatatcaaag atacatctgt
     4381 attgaacgtt atctctgttg tcgaacttta tttctcagga aataccgtgg caacacaaac
     4441 ctatcaatac ttccagacat ttacaatcat cgccgtgatt tactttgtcc tcaccttcac
     4501 cgtaacacgt atcctacgct ttatcgagcg cagaatggac atggatacct acactacagg
     4561 tgctaaccaa atgcaaacgg aggatttgaa ataatgacac aagcaatcct tgaaattaaa
     4621 cacctcaaaa aatcctatgg acaaaacgaa gtgctaaaag acatttctct cactgtccac
     4681 aagggagaag ttatttctat catcggaagc tctggaagtg ggaaatcaac cttcctacgc
     4741 tccattaacc tacttgaaac gccaactgat ggacaaatcc tttatcatgg acaaaacgtc
     4801 ctcgaaaaag gctatgacct cacgcaatac cgtgaaaagt tagggatggt tttccaatcc
     4861 tttaacctct ttgaaaatct caacgttctt gaaaacacaa tcgtcgctca gacaactgtc
     4921 cttaaacgcg aacgcacaga agctgaagaa attgccaaag aaaacctgga aaaggtcggc
     4981 atgggagaac gctactggca agcgagaccc aaacaactct caggtggtca aaaacaacgt
     5041 gtggccatcg ctcgtgccct ttcaatgaat cctgacgcca ttctctttga tgaaccaaca
     5101 tcagctctcg atccagaaat ggttggagag gtcctcaaaa tcatgcaaga tctggctcag
     5161 gaaggcttga ccatgattgt cgtaacccat gaaatggaat ttgcccgtga tgtctctcac
     5221 cgtgttatct ttatggataa gggtgtgatt gctgaagaag gtaaaccaga agacctcttc
     5281 actaatccta aagaagaccg tacaaaagaa tttcttcaac gttatctca
//
LOCUS       DBERAE010000074         5148 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.74, whole genome shotgun sequence.
ACCESSION   DBERAE010000074 DBERAE010000000
VERSION     DBERAE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.74"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            281..1826
                     /locus_tag="ACL70N_002074"
     rRNA            281..1826
                     /locus_tag="ACL70N_002074"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1878..1950
                     /locus_tag="ACL70N_002075"
     tRNA            1878..1950
                     /locus_tag="ACL70N_002075"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1911..1913,aa:Ala,seq:tgc)
     gene            2075..4976
                     /locus_tag="ACL70N_002076"
     rRNA            2075..4976
                     /locus_tag="ACL70N_002076"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5053..>5148
                     /gene="rrf"
                     /locus_tag="ACL70N_002077"
     rRNA            5053..>5148
                     /gene="rrf"
                     /locus_tag="ACL70N_002077"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1460 a         1042 c         1505 g         1141 t
ORIGIN      
        1 acacgggttc gaatcccgta cggactatgg tatgttgcgg ttggaacact tgatgaaaaa
       61 aagtttaaaa aaagcttaaa aatcttcaaa aaagtgttga caagtgaaag tggctgtgat
      121 atactaatat agttgtcgct tgagagaagc aagtgacaaa gacctttgaa aactgaacaa
      181 gacgaaccaa tgtgcagggc gctacaacat aagttgtagt actgaacaat gaaaaaaaca
      241 ataaatctgt cagtgacaga aatgagtaag aactcaaact tttaatgaga gtttgatcct
      301 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
      361 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
      421 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
      481 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
      541 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
      601 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
      661 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
      721 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
      781 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
      841 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
      901 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
      961 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1021 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1081 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1141 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1201 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1261 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt tccttcggga
     1321 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     1381 cccgcaacga gcgcaacccc tattgttagt tgccatcatt cagttgggca ctctagcgag
     1441 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     1501 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     1561 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     1621 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     1681 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     1741 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     1801 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     1861 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     1921 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     1981 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2041 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2101 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2161 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2221 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     2281 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     2341 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     2401 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     2461 acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     2521 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     2581 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     2641 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     2701 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     2761 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     2821 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     2881 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     2941 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3001 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3061 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3121 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3181 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3241 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     3301 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     3361 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     3421 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     3481 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     3541 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     3601 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     3661 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     3721 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     3781 aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc agtgaatagg
     3841 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     3901 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     3961 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4021 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4081 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4141 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4201 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4261 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     4321 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     4381 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     4441 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     4501 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     4561 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     4621 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     4681 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     4741 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     4801 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     4861 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     4921 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     4981 actgagaata tgaaagcgaa cggttttctt aaattgaata gatattcaat tttgagtagg
     5041 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     5101 gaagttaagc cctagaacgc cggaagtagt tgggggttgc cccctgtg
//
LOCUS       DBERAE010000075         4761 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.75, whole genome shotgun sequence.
ACCESSION   DBERAE010000075 DBERAE010000000
VERSION     DBERAE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.75"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(115..390)
                     /locus_tag="ACL70N_002078"
     CDS             complement(115..390)
                     /locus_tag="ACL70N_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGS0590811.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(496..1335)
                     /locus_tag="ACL70N_002079"
     CDS             complement(496..1335)
                     /locus_tag="ACL70N_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0590812.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1477..2325
                     /locus_tag="ACL70N_002080"
     CDS             1477..2325
                     /locus_tag="ACL70N_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS0590813.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFIFGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2418..3335)
                     /locus_tag="ACL70N_002081"
     CDS             complement(2418..3335)
                     /locus_tag="ACL70N_002081"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGS0590814.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3812..3960
                     /locus_tag="ACL70N_002082"
                     /pseudo
     CDS             3812..3960
                     /locus_tag="ACL70N_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            4309..>4761
                     /locus_tag="ACL70N_002083"
     CDS             4309..>4761
                     /locus_tag="ACL70N_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS0590815.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSRMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIDHQLSISTSTVIRKINDFHFKHDFSCLP"
BASE COUNT         1507 a          948 c          770 g         1536 t
ORIGIN      
        1 tacaatattt tcggaacatt caacttttta actctattta ttactagatt tcataattaa
       61 aaagcctact gaccaagcta gaaagcttga tacaataggc tttttaaaga ctgattattt
      121 aacagcgtct ttaagagctt taccagcttt gaatgctggt actttagaag ctgcaattgt
      181 catttcttta ccagtttgtg ggttgcgacc tttacgttct gcacgctcac gaacttcaaa
      241 gttaccaaaa ccgatcaatt gaactttttc accagctgca agatagtcag ctactgctgc
      301 aaatacagct tcaactgctg ctgctgagtc tttcttagtc aattctgtag cttctgctac
      361 tttagcgatc aaatcttgtt tgtttgccat gttaatgatt cctccagata atttctaatt
      421 aacaaatata atcatatcct aaaatccctt ttaggtcaag ttaaaaacgc tatttcttcc
      481 aattttattt attttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
      541 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
      601 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
      661 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
      721 agttccacga cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacaacacg
      781 gatattgaga agggagctca acaagccagt tacacggcca attcgtccac ctttgacaag
      841 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
      901 agataaaatt gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
      961 gaatttcagg gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag
     1021 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
     1081 aagaatctgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
     1141 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
     1201 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
     1261 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
     1321 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
     1381 ctaattatat caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa
     1441 tttgatataa tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt
     1501 tttaccattt tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc
     1561 catcatctct ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa
     1621 atccctgttt ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag
     1681 atctttggag ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg
     1741 ttagcttttt ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca
     1801 gcccttatag cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt
     1861 acaactggcg gaactgatat tctagctcgt attctcaaca aatacactca tatatccata
     1921 ggaaaactgc tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag
     1981 gatttgagat tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat
     2041 ttgattggtg aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac
     2101 caacttgcta aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttttggtcaa
     2161 ggctactata gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt
     2221 gtgaaaacga aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa
     2281 gcccatgaaa tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg
     2341 tgacctcaaa agttagacta aatcatctat cttttgggtt acagacaacc tcttttttgt
     2401 tttatttact caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga
     2461 tccactaatt ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa
     2521 accatgacgg tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt
     2581 gcttcttctc catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt
     2641 ctttgaatct caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa
     2701 agcactaaat tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc
     2761 atacctcttg atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct
     2821 aaaatagctt gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga
     2881 acaatgataa cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa
     2941 ccaaatgtat aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt
     3001 gcaaagaatt cttgtgcagt gagactagcg aattgactac taaaatcaag gagatataat
     3061 tcttctacac cttcgcgctt tagttttctt tcacgttcag cagggttcaa aatatgcaaa
     3121 aacaaatctg gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg
     3181 acgataggta ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc
     3241 cccttatgta tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata
     3301 tctttttggt tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc
     3361 tatttctgga acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca
     3421 aaaagcactt tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact
     3481 tgtaggacat cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg
     3541 tcatactatg cttatgtatg aaaaagcaat gcaactaact cctgagaact ttaaattact
     3601 aattggtgcc gaaaaggtag aatttagaat cgaggtacac ctatggctgt aaaatttaca
     3661 aaatgagaca acttgggcaa gatgtttgaa gaatttccta aactccctga tttgaagcaa
     3721 gtcactttcc ctgatgacaa aaaaagccaa agcagtaaag aaaaactaga tgactgcttt
     3781 ccaacaactt ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 gccattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcaaatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg gtatcaaaat aaaaaggctc tataatattt
     4201 gtagtgggta aatccactat agatattatg gagcctattt tgtgtagaaa aaaagtccca
     4261 tatgacctat aatgaaaagc gatcaaacaa ctcattagaa agattcatat ggaacaatta
     4321 cattttatca caaaattact agacattaaa gaccctaata tccagatttt agacatcatc
     4381 aataaggata cacacaagga aatcatcgcc aaactggact acgacgcccc atcttgccct
     4441 gagtgcggaa atcaattgaa gaaatatgac tttcaaaaac cttctaaaat tccttatctt
     4501 gaaacgactg gtatgcctac tagaattctc cttagaaagc gtcgtttcaa gtgctatcac
     4561 tgttcaagaa tgatggtcgc tgaaacttct atcgtcaaga agaatcacca aattcctcgt
     4621 attatcaacc aaaaaattgc gcaaaagttg attgagaaga tttctatgac cgacattgat
     4681 catcagttgt ctatttcaac ttcaactgtc attcgcaaga tcaatgattt tcactttaaa
     4741 catgattttt cttgtcttcc t
//
LOCUS       DBERAE010000076         4425 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.76, whole genome shotgun sequence.
ACCESSION   DBERAE010000076 DBERAE010000000
VERSION     DBERAE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.76"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            229..2730
                     /gene="leuS"
                     /locus_tag="ACL70N_002084"
     CDS             229..2730
                     /gene="leuS"
                     /locus_tag="ACL70N_002084"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGS0590816.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            3030..3722
                     /locus_tag="ACL70N_002085"
                     /pseudo
     CDS             3030..3722
                     /locus_tag="ACL70N_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            3734..4150
                     /locus_tag="ACL70N_002086"
                     /pseudo
     CDS             3734..4150
                     /locus_tag="ACL70N_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1338 a          831 c         1000 g         1256 t
ORIGIN      
        1 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcgtc
       61 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      121 catagtcatc aaaattaatg agatacagta tacagttttt tctttaaaca catttcaaat
      181 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttat
      241 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      301 acaggaacag atacatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      361 ggagttggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      421 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      481 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      541 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      601 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      661 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      721 gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg ctatccagtt
      781 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      841 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      901 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
      961 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtctt ggctcctgaa
     1021 catgaattag tagacgctat cacaagttca gagcaagcag aagctgtagc agactataaa
     1081 caccaagcca gccttaagtc tgacttggtt cgtacagacc ttgctaagga aaaaactggt
     1141 gtttggacag gtgcctatgc catcaaccct gtcaatggta aggaaatgcc aatctggatt
     1201 gcggactatg ttcttgctag ttatggaaca ggtgcggtta tggctgtgcc tgcccacgac
     1261 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1321 ggaaatgtcg aagaagctgc ctacacagag gatggcctgc atgtcaattc agacttccta
     1381 gatggattga ataaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1441 tgtggtcagg agaaggttac ctaccgcctc cgcgactggc tctttagccg tcaacgttac
     1501 tggggtgagc caattccaat cattcattgg gaagatggaa cttcaacagc tgttcctgaa
     1561 actgaattgc cgcttgtctt gcctgtaacc aaggatatcc gtccttcagg tactggtgaa
     1621 agtccactag ctaacttgac agattggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1681 cgtcgtgaaa ctaacaccat gccacaatgg gctggttcaa gctggtacta cctccgctat
     1741 attgacccgc acaatactga gaaattggct gatgaggacc tcctcaaaca atggttgcca
     1801 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta tgctcgtttc
     1861 tggcataaat tcctctatga cctcggtgtt gttccgacta aggaaccatt ccaaaaactc
     1921 tttaaccaag ggatgatttt gggaacaagc taccgtgacc accgtggtgc tcttgtggca
     1981 accgacaagg ttgaaaaacg tgatggttcc ttctttcatg tagaaacagg ggaagagttg
     2041 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgttaaccc agacgatgtg
     2101 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgtttatggg accactcgat
     2161 gcttcgattg cttggtcaga agaaggtttg gaaggaagcc gtaagttcct tgaccgagtt
     2221 taccgtttga ttacaagtaa agaaatcctt gcggaaaaca atggtgctct tgacaaggtt
     2281 tacaacgaaa cagtcaaagc tgttactgag caaattgagt ctctcaaatt caacacagct
     2341 attgcccaac ttatggtctt tgtcaatgct gctaacaagg aagataagct ttatgttgac
     2401 tatgccaaag gctttattca attgattgca ccatttgcac ctcacttggc agaagaactc
     2461 tggcaaacag tcgcagaaac aggtgagtca atctcttatg tagcttggcc aacttgggac
     2521 gaaagcaaat tggttgaaga tgaaattgaa attgttgtcc aaatcaaagg aaaagtccgt
     2581 gccaaactca tggttgctaa agatatatca cgtgaagaat tacaagaaat cgctttagct
     2641 gatgaaaaag tcaaagcaga aattgacggt aaggaaatcg tgaaagtaat tgcggtaccg
     2701 aataaactcg ttaatatcgt cgttaaataa cgagtttatt agctctatct gccaccttca
     2761 atagtccact ggactattga agccaactaa attagttaac attgttgtga aataagatag
     2821 gaatccttca gagtagaatc tggaggattt tttgaacctt cttatgaaag tatgatatat
     2881 agtagactga atctaaaata gtacgaaaca attgctaaaa catttataga aattaatttt
     2941 actttcccaa tcgatttgtt ctcatcttat ttcaatacgc tatactatgg gcaactataa
     3001 agtttgaaaa gcgaaacaag gagaaagtta taccagtaaa cgaatatggt cagatgattg
     3061 gtgagtcaat ggaaggttat acaccaggtg aactgacttt tattgatctc ttagaagggc
     3121 gttatgctag gatagaggct ctttcagtgg aaaagcatgc ggaggatttg ctagctgttt
     3181 atggtcctga tactcctcag gagatgtgga cctacctctt tcaggagcca gtagcagaca
     3241 ttgaggaact ggtcagcctt ttaaatcaga tgttggtcgt aaggaccgtt tttactatgc
     3301 aatcatagac aaggcaactg gtaaggcttt gggaactttt tctctcatgc gtattgacca
     3361 gtaacggagt aatagaagtg ggagctgtca ctttttctcc aaaactcagg gggacacgga
     3421 tagggacaga agcccagtat ctactggctc gctatgtctt tgaagagctt aactatcgtc
     3481 gttatgagtg gaaatgcgat gctcttaacc tgccatccag acgtgctgcg gagcgtttgg
     3541 gctttattta tgaaggaacc ttccgtcagg cagtggttta taaggggcgt acgagagata
     3601 tggattggtt gtctatgatt gataaggact ggcccaaagt caaagatcgt ttggaaacat
     3661 ggttgcgtcc tgaaaatttt gataaaaatg gacagcagta caagagcttg agagagtttt
     3721 aagaggtgtt gacatgatca ctattagaaa gcaagaaatc gtcaagttcg aggatgtttt
     3781 gcatctctat caggctgtcg gttggacaaa ttatacaaat caacctcaga tgctggagta
     3841 gaccttgtat cattcattaa taatttatct ggcacttgat ggtgatgctg ttgtgggctt
     3901 gattcgtttg gttggagatg gtttttcatc agtttttgta caggatttga ttgttttgtc
     3961 tagctatcag cgccaaggga ttggtagctc cttgatgaaa caggctttag gaaattttaa
     4021 agaggcctat caagtccagc tggcgacaga acagacagaa aaaaacgtgg gatttaatcg
     4081 ttctatgggc tttgaaatct tatccaccta taattggata gggatgactt ggatgaatcg
     4141 taaaaaataa caaaacttgt tttttcttaa gcaaaattta aggatggtct agtattatat
     4201 aatcattaaa taaagacctc ctaactttat ttaataaaat cctaaacttt tttcatcaca
     4261 atctcctaat gaagccaccc aatcaggtgg cttttttgcg tggtgaggtg ctggtgatag
     4321 aaattttttg caaaatagta aaattttaga aaagttaagc tagttttaag tttcgtcttg
     4381 tatcatgtag ttattaaata aagacctcct aactttattt aataa
//
LOCUS       DBERAE010000077         4185 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.77, whole genome shotgun sequence.
ACCESSION   DBERAE010000077 DBERAE010000000
VERSION     DBERAE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.77"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            74..319
                     /locus_tag="ACL70N_002087"
     CDS             74..319
                     /locus_tag="ACL70N_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590817.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            720..1712
                     /locus_tag="ACL70N_002088"
     CDS             720..1712
                     /locus_tag="ACL70N_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0590818.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="ACL70N_002089"
     CDS             1714..2532
                     /locus_tag="ACL70N_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590819.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="ACL70N_002090"
     CDS             2534..3319
                     /locus_tag="ACL70N_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0590820.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="ACL70N_002091"
     CDS             3417..3635
                     /locus_tag="ACL70N_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGS0590821.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3817
                     /locus_tag="ACL70N_002092"
     CDS             3620..3817
                     /locus_tag="ACL70N_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0590822.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
BASE COUNT         1161 a          719 c          907 g         1398 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggggagtt
     2821 tgacaagtat ttgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt tctcagctat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgccatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattattt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcttcgaa
     4141 aatctcttca aaccacgtca acgtcgcctt gccgtgcgta tggtt
//
LOCUS       DBERAE010000078         3395 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.78, whole genome shotgun sequence.
ACCESSION   DBERAE010000078 DBERAE010000000
VERSION     DBERAE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.78"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            4..77
                     /locus_tag="ACL70N_002093"
     tRNA            4..77
                     /locus_tag="ACL70N_002093"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38..40,aa:Asn,seq:gtt)
     gene            243..452
                     /locus_tag="ACL70N_002094"
                     /pseudo
     CDS             243..452
                     /locus_tag="ACL70N_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(487..1284)
                     /locus_tag="ACL70N_002095"
                     /pseudo
     CDS             complement(487..1284)
                     /locus_tag="ACL70N_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1549..1785
                     /gene="comW"
                     /locus_tag="ACL70N_002096"
     CDS             1549..1785
                     /gene="comW"
                     /locus_tag="ACL70N_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGS0590823.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            2016..3302
                     /locus_tag="ACL70N_002097"
     CDS             2016..3302
                     /locus_tag="ACL70N_002097"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGS0590824.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
BASE COUNT         1000 a          487 c          739 g         1169 t
ORIGIN      
        1 taatccgcca tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc
       61 gagtcctact ggcggagtaa tttagttaag aggtttagac ctcttttttg ttatgtaata
      121 ataatctatt tcgtgttata gtaaaatgaa ataagaatag gacaaatcga tcaggacagt
      181 aaaatcgaat tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact
      241 atattatgga caatgcaaga ttccatagaa tgggtaagct agaactcttg tgtgaagagt
      301 ttgggcataa acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
      361 catgggttca tatcaaaaag aaccccaaaa aggtattagc aagttgcaat accttttatg
      421 aggctctttt gtcttgttct tgtttcaatt gactatatta gaggcgagac atttttcggt
      481 tctttgtcaa ctgtagtggg ttgaagaaag cgaagatcta gaaaggacaa atttcgtcct
      541 ttcttttttg aagttttcaa agttcctaaa accaaaggca ttgtacttga taagtttgat
      601 gagattattg gtggcttcca gtttggcgtt ggaataaggt aattgaaggg cgttgacgat
      661 tttctcttta tctttgagga aggttttaaa cagagtctga aaaagaggtg gaaaagcaag
      721 agctgataga gattatagtg gtgtttcaag tcttcggaat agctcaaaag tttatctaga
      781 atttctttat tagtcaagtg catacgaaaa gtagggcgat aaaatcgttt atcactcagt
      841 ttctgactat cttgttgaat gagctttcag tatcgcttga tagccttgta ttcatgggat
      901 ttcggatgat ggcttgtgtt ctgctctcaa gaacagttat gatattgagc ttatcaaagt
      961 cttgagcaat aaagctcatc tccatctccc gattgaaaca gtcactcccc ggactgtttc
     1021 aacgtcctag gacataatct caggaagacg cgaaaaatca tgctcaaagt gaaaatcatt
     1081 gatcttgcga atgacagttg aagttgaaat agacaactga tgatcaatgt cggtcataga
     1141 agtcttttta attagcttct gagcaatctt ttggttgatg atacaaggaa tttgatgatt
     1201 cttcttgacg atagaagttt cagcgaccct catttttgaa cagtgatagc acttaaaacg
     1261 gccttttcta agaagaattc tagtttgaat tttttatact agaaaatcag aaccataata
     1321 cctatataaa aatattatag ttctaatagg atttacccaa aagttttaag gcggtctttt
     1381 tagaacttta atcgtttgaa atttaggtag caaatttgtt tctattctgt caacttttcc
     1441 tatttttatc ttgttgaggc tggtatttta acaattcagg aattgatagt gaatgtgtaa
     1501 aattttttgt tagaataagt ttataaaaaa gaaaaggagt atttgattat gttacaaaaa
     1561 atttatgagc agatggctaa tttctatgat agtattgaag aagagtatgg tcctacattt
     1621 ggtgataatt ttgactggga acatgttcat tttaaatttt taatttatta tttagtgaga
     1681 tatggcattg gttgtcgtaa ggattttatt gtttaccatt atcgtgttgc ttatcgtttg
     1741 tatcttgaaa aattggtaat gaatcggggt tttatttctt gttgaggtaa ttttagtaaa
     1801 tttccgaact aatttactct tttatggaaa gatgatagta aatagctagt aatttttcta
     1861 aatcattttt taatagttgg aaatagcaaa tctttctatt gtttcttctt gataaaaaga
     1921 cgatttttta ttataataaa ttgtaagata taattgcagg tgagagtcct gccatgtatg
     1981 tgagaaagga agagcctgag ggctcagaca agattatgac ttcagttgtt gttgtaggta
     2041 cccaatgggg tgatgaaggt aaagggaaga ttacagactt cctttcagcg aatgcagaag
     2101 tgattgcacg ttaccaaggt ggtgataatg ctggtcacac gattgtgatt gacggtaaga
     2161 aatttaagtt gcacttgatt ccatctggga ttttcttccc tgaaaaaata tctgtcattg
     2221 ggaatggtat ggttgtaaat cctaaatctc ttgtaaaaga gttgagctat cttcatgagg
     2281 aaggtgtaac aactgataac ttgcgtattt ctgatcgtgc gcatgttatt ttgccttatc
     2341 atatcgagtt ggatcgcttg caagaagaag ctaagggcga caataagatt ggtacgacaa
     2401 ttaagggaat tggtccagct tatatggaca aggctgctcg tgttggaatt cgtattgcag
     2461 atcttttaga taaagatatt ttccgtgagc gtttagaacg taaccttgct gaaaagaatc
     2521 gtctttttga aaaattgtat gacagtaaag cgattgtttt cgatgatatt tttgaagaat
     2581 attacgaata tggtcaacaa atcaagaaat acgtgataga tacatctgtt atcttgaatg
     2641 atgcgcttga taatggcaaa cgtgtgcttt ttgaaggtgc acaaggtgtt atgctagata
     2701 tcgaccaagg tacttatcca tttgttacgt catcaaaccc tgtagctggt ggtgtgacaa
     2761 ttggttctgg tgtcggtcca agcaagattg acaaggttgt aggtgtatgt aaagcttata
     2821 cgagtcgtgt aggagatggt cctttcccaa ctgagttgtt tgatgaagtg ggagaacgta
     2881 tccgtgaagt gggtcatgag tatggtacaa caactggtcg tccacgtcgt gtaggttggt
     2941 ttgactcagt tgtgatgcgt catagccgtc gtgtttctgg tattactaac ctttctttga
     3001 actctattga tgttttgagc ggtttggata ctgtgaaaat ctgtgtggcc tatgatcttg
     3061 acggtcaacg tattgactac tatccagcta gtcttgagca attgaaacgt tgcaagccta
     3121 tctatgaaga gttgccaggt tggtcagaag atattaccgg agttcgcaat ttggaagatc
     3181 ttcctgagaa tgcgcgtaac tatgttcgtc gtgtgagtga attggttggc gttcgtattt
     3241 ctactttctc agtaggtcct ggtcgtgaac aaacaaatat tttagaaagt gtttggtcct
     3301 aagagatttt taagatttgt ttaagatagg tcgggtatac tatagacggt tacaagaaga
     3361 cctcctaact tgttgtaaca aatatcctaa acttt
//
LOCUS       DBERAE010000079         3322 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.79, whole genome shotgun sequence.
ACCESSION   DBERAE010000079 DBERAE010000000
VERSION     DBERAE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.79"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(189..800)
                     /gene="rpsD"
                     /locus_tag="ACL70N_002098"
     CDS             complement(189..800)
                     /gene="rpsD"
                     /locus_tag="ACL70N_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGS0590825.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(995..2047)
                     /locus_tag="ACL70N_002099"
     CDS             complement(995..2047)
                     /locus_tag="ACL70N_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0590826.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2044..2742)
                     /locus_tag="ACL70N_002100"
     CDS             complement(2044..2742)
                     /locus_tag="ACL70N_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0590827.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2909..>3322)
                     /locus_tag="ACL70N_002101"
     CDS             complement(2909..>3322)
                     /locus_tag="ACL70N_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HGS0590828.1"
                     /translation="ATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPS
                     NSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLP
                     NTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          925 a          746 c          633 g         1018 t
ORIGIN      
        1 ccataaaaga ttataccaca ttgtgtacta tttttggttc attttactat atcactttgg
       61 actatatcgg tctagttatg tctaaacgat tatagctgga tactaagaga aatcaaaaaa
      121 gcactaaggg agaacgtccc aaagtgctta gtttcaaggc tttacagcct atcttattta
      181 ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg
      241 ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaatttttc agcgtcgaat
      301 gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc tggaactttc
      361 aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga tgggatatca
      421 acgcgtttcc cgtcaacaag gatgtgaccg tggtttacaa attgacgagc ttgacgacga
      481 gtagtcgcga gaccaagacg gtaaacaacg ttatccaaac gacgttccaa aagaagcata
      541 aagttgaaac ctaggattcc gcctttgatt tttgtagctt gtacaaacaa gttacggaat
      601 tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg
      661 tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt
      721 gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg tttccaagat
      781 ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt cggtggaaat
      841 agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt
      901 atcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac acaaaattca
      961 ttctaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca ctaccagaga
     1021 ggttgagaac gagagtaaag gtacttccta gaccgtactg gctgctgact gtgatttccc
     1081 cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct
     1141 tcatgttacg cgaagtttcg acacgataaa ggcgtttgaa aatattttcc aaatcctctg
     1201 gggcaatgcc ctgcccttca tcggtcacac tgattgaaag ctggcccttc tccagcttag
     1261 ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg accagattca
     1321 ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct gggattacct
     1381 gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc atgcactcaa
     1441 ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga tttctagctg
     1501 tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc gtctggcgtc
     1561 caatggttgc tagataatga gcttgctccg actccttgat aatcccatcc aaaatccctt
     1621 ctaccgtcgc ttggatcgaa gtgataggag tcttaatatc atgcgacaac tgagcaatca
     1681 tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc aaatcatggg
     1741 acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga acctccaaat
     1801 ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg cccaacgacg
     1861 taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg gcaacgatgg
     1921 tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga acagcccaaa
     1981 aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata taacttttta
     2041 gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa ctgtcttaat
     2101 agtgggcgtt tggtcactac tatattttgc cagctcctgt cgaagagcat ggatatgcac
     2161 attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat agaggtctgt
     2221 cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa atgatttaac
     2281 agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat tcatttttag
     2341 attgccaagg gaaatcagct ctgtttcgcc cccacgatga aggcggcgca aaatattgtg
     2401 gacacgcaaa actagctcac gtgggctaaa aggcttagca ataaaatcat ctgctcccaa
     2461 gctcaggccg taaatcttgt cctgctcact ggtcttagca gtaataaata ggaaaggctg
     2521 ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc gaggcatcat
     2581 gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg cttccagtcc
     2641 atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat gaatatctgt
     2701 gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct cctttgataa
     2761 aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga tgattttaat
     2821 ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct tagtcagccc
     2881 actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt ttcaaaccta
     2941 gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc attgatgttt
     3001 gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta tcagacatct
     3061 tgttagcaga agcagccata ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt
     3121 cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga gtcacgccag
     3181 aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct ttaacattta
     3241 tcttaatagt gactttttta gttgctacga tgttgtccaa gtctggttta ccgtctttgt
     3301 taccatagac attgactgta gc
//
LOCUS       DBERAE010000080         3290 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.80, whole genome shotgun sequence.
ACCESSION   DBERAE010000080 DBERAE010000000
VERSION     DBERAE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.80"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            607..1953
                     /gene="gdhA"
                     /locus_tag="ACL70N_002102"
     CDS             607..1953
                     /gene="gdhA"
                     /locus_tag="ACL70N_002102"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGS0590829.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2459..2629)
                     /locus_tag="ACL70N_002103"
     CDS             complement(2459..2629)
                     /locus_tag="ACL70N_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590830.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2642..3214)
                     /locus_tag="ACL70N_002104"
                     /pseudo
     CDS             complement(2642..3214)
                     /locus_tag="ACL70N_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT         1041 a          608 c          540 g         1101 t
ORIGIN      
        1 aaatcgttgt ttgattacag tctaaaagct ctataatctc tttataagat ttgcccatca
       61 gacgaaatat agtagattga aactagaata gtacacctct acttctaaaa cattgttaga
      121 aatcgatttg actgtcctga tcgatttgcc ctgttcttgt ttcgttttac tatagaacga
      181 tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggctt
      241 ggatttcttc tttagttgat ttcatatcac tattatataa tgctttttga ttttagtctg
      301 gtataaatat tgctttcctc caaaatggtc ataattttac tagcaaatct aacatatcac
      361 ggataaatta acaagtgatt tctgaattgc taaacatttt cttttcttat agcataccat
      421 actttaagat tttgtctttg agaaagatat ttccaagaaa aacgttcgtt tttttatcta
      481 ttttcaaaaa aaaccaaaaa ctgaattgaa agaattttta gaaaatttct gttttttctt
      541 tacagtgaaa aaaaattctg ctataatgtc ttatgtaata aaatatgaca ataaaaggag
      601 aacgatatga catctgctaa agaatatatc caaagcgtgt ttgaaactgt aaaagctcgt
      661 aacgggcacg aggctgaatt cctccaagct gttgaagaat ttttcaacac tttggaacct
      721 gtatttgaaa aacaccctga gtatatcgaa gaaaatatct tggcacgtat tactgagcct
      781 gagcgcgtga tttctttccg tgttccttgg gttgaccgtg atggaaaagt tcaagtaaac
      841 cgcggctacc gtgttcaatt caactcagct gttggaccat ataaaggcgg acttcgtttc
      901 cacccaactg taaaccaagg gattttgaaa ttcctcggat ttgaacaaat ctttaaaaac
      961 gtcttgactg gacttcctat cggtggaggt aaaggtggat cagacttcga tcctaaaggt
     1021 aaaacagatg ctgaagtgat gcgcttctgc caaagcttca tgactgaatt gcaaaaacac
     1081 atcggaccat cacttgacgt acctgctggt gatatcggtg ttggtggacg tgaaattggt
     1141 tacctttacg gtcaatacaa acgtcttaac caatttgatg ctggtgtctt gactggtaaa
     1201 cctcttggat ttggtggtag cttgattcgt ccagaagcaa ctggttacgg tttggtttac
     1261 tatactgaag aaatgctcaa agctaacggt aacagctttg ctggtaagaa agtcgttatt
     1321 tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag caactgaact cggtgcaact
     1381 gttatttctg tttctgactc aaatggttat gtcatcgatg aaaatggtat cgacttcgat
     1441 cttttggttg atgttaaaga aaaacgtcgt gctcgtttga ctgagtatgc agctgaaaaa
     1501 gcaactgcaa cctaccacga aggtactgta tggacttacg ctggaaacta tgacattgct
     1561 cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag ctaaacgttt ggttgctcaa
     1621 ggcgttatct gtgtatctga aggtgccaac atgccgagcg accttgatgc catcaaagtt
     1681 tacaaagaaa atggtatctt ctacggacct gcaaaagctg ccaacgctgg tggtgtagcc
     1741 gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct catggactcg tgaagaagtt
     1801 gatggccatc tcaaagacat catgacaaac atcttcaaca cagctaaaac gacttcagaa
     1861 acatacggtc ttgataaaga ctaccttgca ggagctaaca ttgctgcctt tgaaaatgta
     1921 gcaaatgcca tgattgcaca aggtattgtt taagatttat ttactcaatc ctcaatcact
     1981 acgattgggg atttttagct tgaattaaaa aattggaaaa tctaattaaa taaaatgaaa
     2041 tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac atacttctag
     2101 aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta ctatacttac
     2161 ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag ccgcaggctg
     2221 tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa gagtattaaa
     2281 caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta agctactact
     2341 gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag ctttttgtta
     2401 gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa aattatgctt
     2461 aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc aacaagccta
     2521 aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt ccaatcatca
     2581 cccctagtga ggctgttgtt aaaattacat attcattttc tttcttcatt ttctttacac
     2641 ctcatttcct ttttgtatat aagctgtagt actctccacc aagctccatt aagtacttat
     2701 gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc gcatccttaa
     2761 tcgttgacaa tctatgagct acaattattt gagtacagcc ctgacttttt atatactttg
     2821 ttattctttc ctcattaata gtgtctaaag cactagttgc ttcatctaaa attacaatac
     2881 taggattatt tattaatgca cgtgccagtg ctatccgttg tctttgacca cctgaaatat
     2941 ttgaacccat ctctgagatg atagtattaa atttcatcgg catagccatg atttcatcat
     3001 agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg ttctttaaag
     3061 ttatattatc aagaatactt cggttcaata aaaatgaatc ctgtggaact actcctaaat
     3121 tttgacttaa tattttttta tctatttgat taatatttat accatcaaat aaaacttttc
     3181 ctgtatcaat cttatataat cctgatggta tttttgataa tagacttcct gcaaaactag
     3241 aatcctagtt catgattgat aataccagca ctcaaattca ttcgtaatcc
//
LOCUS       DBERAE010000081         3211 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.81, whole genome shotgun sequence.
ACCESSION   DBERAE010000081 DBERAE010000000
VERSION     DBERAE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.81"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..1061
                     /locus_tag="ACL70N_002105"
     CDS             <1..1061
                     /locus_tag="ACL70N_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGS0590831.1"
                     /translation="IKSLEILSNQEVKLIDSKVFIDATGNATIASASGADVYEKNSSY
                     GCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLANRKYRATGAVLKDPVSYDH
                     APMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNELKKAVESGDFNFEIYHDD
                     KSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDESHANILSRKYNLTFLSFLK
                     KYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPMYTFKTMYSYQTPKEITYK
                     SIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAAKTIIEDKSNTLNINRDLF
                     KSNLDILFTWEFSNWITD"
     gene            1083..1538
                     /locus_tag="ACL70N_002106"
     CDS             1083..1538
                     /locus_tag="ACL70N_002106"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS0590832.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            1625..2031
                     /gene="cdd"
                     /locus_tag="ACL70N_002107"
                     /pseudo
     CDS             1625..2031
                     /gene="cdd"
                     /locus_tag="ACL70N_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008655 - pyrimidine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            2044..2493
                     /locus_tag="ACL70N_002108"
     CDS             2044..2493
                     /locus_tag="ACL70N_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0590833.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKVKI"
     gene            complement(2605..3211)
                     /locus_tag="ACL70N_002109"
                     /pseudo
     CDS             complement(2605..3211)
                     /locus_tag="ACL70N_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1143 a          426 c          562 g         1080 t
ORIGIN      
        1 atattaaaag tcttgaaatt ttaagtaatc aggaagttaa attgattgat tctaaagttt
       61 ttattgatgc tacagggaat gcaacaattg cttctgctag tggagctgat gtttatgaaa
      121 aaaattcttc ttacggttgt ttaatgagag ttggaggagt tgatatctca aagactatag
      181 aacatattga aaaaacaaag cagtggaact atatagaagg atataatcag tggttagaag
      241 aagtattagc aaatcgaaag tacagagcca ctggagcagt tttaaaagat ccagtttctt
      301 atgatcatgc ccctatgctt tcaaaagacg accattttat gaatgatgaa aaatggaatt
      361 acattaaaga aagatgggaa aaatttagat ttatttacac tttagaagta tcactattta
      421 ggaatgaatt aaaaaaagct gtagaatctg gggattttaa ttttgaaatt tatcatgatg
      481 ataaatctgg agtcactatg aatggcgacg gtataagcta tggttcatgg ggtcaaaatg
      541 tagcattaat taatgttgca aaagcatttg gattcaatcc caaatatatg gaagatgaat
      601 cacatgctaa tattctttct agaaaatata atttaacatt tttatctttt cttaaaaaat
      661 atgtaccagg ttttgaaaat tcttttatcc ttgatcaggg aactagagct actaacagat
      721 catgtaggca cattgataat tcatctatga tggacgaaat tcttgatttt ccaatgtata
      781 catttaagac tatgtatagc tatcaaactc ctaaagaaat aacgtacaaa tcaattgtag
      841 gtggaaaatt gaataatttg tttgtaatag gtaaaggtgc ttaccaatcc gaaagtttta
      901 gatcacaaat tagttgtatg ttaatgggga tatcatcagc agcagcggca aaaactatta
      961 ttgaagataa aagcaatact ctaaacatta atagagattt gtttaaatcg aacttagata
     1021 tattatttac atgggagttt tctaattgga ttactgatta acaaataata agggaatatt
     1081 aaatgaatga tactaataaa aatcaatact ttgtttatga atttgatact agctttgtag
     1141 aaatgtctta ttctcagttt tttgaaggat attgtattct tttttcaaaa gaaccctatc
     1201 cttctttatc tgatatgcca atggaattta gaaaagaatt tttaatggaa atgagtatat
     1261 taggtgatgc gatgcttgaa gtgttaaatg cctatagaat taattatgat atcttaggaa
     1321 attcaacacc tgtacttcat gctcatttat ttccgagata catgtgggaa gaggaagaga
     1381 gaagaaaaac tgtagttcat agatatgatt cttcagtttt tagcaatcct gagtttgaat
     1441 ttactataga aaagcatgga ccaattatta aaaaactgag gtctgctatt gatagacatt
     1501 atagagagta tcaacaatta ttagatgatt caaactgaac tccacatttt cgattagatt
     1561 taataccttg tatattacaa ctaggttgtg gatgatataa ttttttgaaa aatatatttt
     1621 aggaatgact tataaagcaa ttatatcaga ggctattaaa tcaatggcca aagcttatgc
     1681 tccttattct gattttaagg ttggagctgc gttagtaact gaagataaaa aattttttct
     1741 ggatgtaata tagaaaatgc tgctttttct cctacttgct gtgcagaacg agtatctttt
     1801 tataaagctg tatttaaagg agaacgttcg ttttcaagaa tatgtattgt aggtggaaaa
     1861 aatggtatct tatcatcttt tatagcacct tgcggagtgt gtcgccaggt aatgatagaa
     1921 ttttgtaatt ctgattcatt tgaagttata ttggctagtg atgttgatac ttataaagta
     1981 tataaactta aagaactact accagttagt tttaatcaag aaaatttata acaggaggga
     2041 actatggaat tagttgaatt taaaaatgga catgttaata cggttcatga gcatatcgca
     2101 ataacgaaag taaaagagtt tctaaataat catgatatac caaaagataa aggtggcata
     2161 cataaaattt ctactgattt cttttacaat ataattgata tggaaactac aactgaagag
     2221 aatagaccgt gggaaagtca taaggaatat tatgatgtcc attatctgtt aaatggagaa
     2281 gaaataattt tatataattt cttgtctcaa atggaattgt ctgaatataa agtagatgat
     2341 gattggcaac aaatgaatgg gacagcttta tttagtatta aattaaagaa agatatgtta
     2401 cttttgttgg aaccaaacga tgcacataaa acaggcctat tggttgaaga accacttaat
     2461 attaagaaag ttgtttttaa ggtaaaaatt taactgaaag tactttcggg gattaagaat
     2521 tttaaaatat ttaagaaatt gtattctaaa gttctaaaat tatagatatt taatttaaag
     2581 cttgttaaaa tagaatagta acactcatct gctttcaaaa agcattctag tccatctccg
     2641 attaacgatg gactttatca cctccttctc cagtccttgt atgacatctt gaagttgatt
     2701 catgacatct tccaaaattc gaaaggcttt attcttaaat ccacgtttac gaatctcttt
     2761 ccacacttgt tcaatggggt tcatctctgg tgtgtatgga ggaataaatg caaaaccaat
     2821 attagtcgga atctttaaga tacttgattt atgccatata gcattgtcca taacgagtaa
     2881 aaaataatca tctggataag cttgtgaaag ctcttctaaa aagacgttca tccactcagt
     2941 attacatcca ccagctctta agaaaaatga ttcgcctgta taggcatcaa cagctccata
     3001 acaatagcga aattctcgta tatagtgact atggacatgt ggacctactc ctattggaga
     3061 ccaacaagat cccagtttac tgattctacc gaaaccagcc tcatcttggt acatcaagcg
     3121 aaccttatga aaaggtctac tggttttaaa gcgctttctt gtcttcttga attgagattt
     3181 tatttttaga cgcgacaatg gtttgagcgt c
//
LOCUS       DBERAE010000082         2952 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.82, whole genome shotgun sequence.
ACCESSION   DBERAE010000082 DBERAE010000000
VERSION     DBERAE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.82"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(85..1026)
                     /locus_tag="ACL70N_002110"
     CDS             complement(85..1026)
                     /locus_tag="ACL70N_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS0590834.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL70N_002111"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL70N_002111"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGS0590835.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
BASE COUNT          859 a          697 c          591 g          805 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacataca tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcatgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accaacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggcattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgcttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tctttctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggttactga ct
//
LOCUS       DBERAE010000083         2943 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.83, whole genome shotgun sequence.
ACCESSION   DBERAE010000083 DBERAE010000000
VERSION     DBERAE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.83"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            61..777
                     /gene="ldcB"
                     /locus_tag="ACL70N_002112"
     CDS             61..777
                     /gene="ldcB"
                     /locus_tag="ACL70N_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGS0590836.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKAQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELLKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(817..954)
                     /locus_tag="ACL70N_002113"
     CDS             complement(817..954)
                     /locus_tag="ACL70N_002113"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590837.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEIADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            1086..1511
                     /gene="rplK"
                     /locus_tag="ACL70N_002114"
     CDS             1086..1511
                     /gene="rplK"
                     /locus_tag="ACL70N_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGS0590838.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1719..2408
                     /gene="rplA"
                     /locus_tag="ACL70N_002115"
     CDS             1719..2408
                     /gene="rplA"
                     /locus_tag="ACL70N_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGS0590839.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          987 a          550 c          657 g          749 t
ORIGIN      
        1 aagattagtc aaacgtttat cgttagaagt agataaacta ttagaaataa aggagtagaa
       61 atgaaaaaaa gatacctagt cttgacagct ttgctagcct tgagtctagc agcttgttca
      121 caagaaaaag caaaaaatga agatggagca gctaaaacag aacaaacagc taaagctgat
      181 ggaacagtag gaagtaaggc tcaaggagct gcccagaaaa aagcagaagt ggttaacaaa
      241 ggagactact acagcatcca agggaaatac gatgaaatca tcgtagccaa taaacactat
      301 ccattgtcta aagactacaa tccaggtgaa aatccgacag ccaaggcaga attgctcaaa
      361 ctcatcaaag caatgcaaga ggcaggtttc ccgattagcg atcattacag tggttttaga
      421 agttatgaaa ctcagaccaa gctctatcaa gattatgtta accaagatgg gaaggcagca
      481 gctgaccgtt actctgcccg acctggctat agtgagcacc agacaggctt ggcctttgat
      541 gtgattggga ctgatggtga tttggtgaca gaagaaaaag cagcccaatg gctcttggat
      601 catgcagctg attatggctt tgttgtccgt tatctcaaag gcaaggaaaa ggaaacaggc
      661 tatatggctg aggaatggca cctgcgttat gtaggaaaag aagctaaaga aattgctgca
      721 agtggtctca gtttggaaga atactatggc tttgaaggcg gagactacgt cgattaatac
      781 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac ctactgactg cgtcggttct
      841 attcacaacc tcaaaacagt gttttgagct gacttcgtca gttttatctg caatctcaaa
      901 gctgtacttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
      961 taaaaaataa acttttctct tgcaattcca gataaatagt gtataatgga tgggtatgtg
     1021 aaaaacatac ttgtgggagg taaaaatctc taattaccgc caaaaccaca aaggaggatt
     1081 taaaaatggc taaaaaagtc gaaaaacttg taaaattgca aatccctgct ggtaaagcta
     1141 caccagctcc accggttgga cctgctcttg gtcaagctgg tatcaacatc atgggattca
     1201 caaaagagtt caacgctcgt acagctgacc aagctggtat gatcattcca gttgttatct
     1261 cagtttacga agacaaatca tttactttcg ttacaaaaac accaccagct gctgttcttt
     1321 tgaaaaaagc tgcaggtgtt gaaaaaggat caggtacacc taataaaact aaagttgcta
     1381 cagttactcg tgcacaagta caagaaattg cagaaactaa gatgccagat ttgaacgcag
     1441 caaacgtaga gtctgcaatg cgtatgatcg aaggtactgc tcgttctatg ggattcactg
     1501 ttgttgacta atcaataaca cagtagaaaa tctcacagca gtctattagt tgcttttcat
     1561 actaggcaag tgactgagcc ttgtacttgg gtacagcaag ggagcttaag gccgtaggaa
     1621 gagaaaaata gtagactgaa aacccgcaag acttcatcat ttcgagaagt gacgtgggag
     1681 atgaaaatcg attgaaccac ttacaaggag aatagaaaat ggctaaaaaa agcaaacaac
     1741 ttcgtgctgc tcttgagaaa atcgacagca caaaagcata cagtgtagaa gaagctgtag
     1801 cacttgcaaa agaaactaac tttgcaaaat ttgacgcaac tgtagaagtt gcttacaact
     1861 tgaacatcga cgttaaaaaa gctgaccaac aaatccgtgg agcaatggta ttgccaaacg
     1921 gtactggtaa aacttcacgt gttcttgttt tcgcacgtgg tgcaaaagct gaagaagcaa
     1981 aagctgctgg tgcagacttt gttggtgaag atgaccttgt tgctaaaatc aacgacggtt
     2041 ggttggactt cgacgtagtt atcgctacac ctgatatgat ggctcttgtt ggacgtcttg
     2101 gacgtgtcct tggaccacgt aacttgatgc caaaccctaa aactggtact gtaacaatgg
     2161 atgttgctaa agcagttgaa gagtctaaag gtggtaaaat cacttaccgt gctgaccgtg
     2221 caggtaacgt tcaagcaatc atcggtaaag tatcatttga agctgaaaaa ttggttgaaa
     2281 actttaaagc tttcaacgaa acaatccaaa aagcaaaacc agctacagct aaaggaactt
     2341 acgtaacaaa cttgactatc acaactactc aaggtgttgg tatcaaagtt gacgtaaact
     2401 cactttaatc agtagttaaa gtaatgtaaa aaagttgaag acactatgtc tcaacttttt
     2461 ttgatgtacg acgggcatgt cgtatatctg aggtgtaagt cctcggtggg cacctactac
     2521 cggtgaaccc aatagcgatt cccaagtctg actatcgtga ggtagcggat taaaacggtc
     2581 tggggataga ccgttttaag tctgacgctg gaaataagaa tcgtcagagg aagggatagc
     2641 gaaatcgtgg ctctacgaac aggaacgtga taataaggcg tatatagcgg ataaggtatc
     2701 tggctggggc gaccactatc aattataata aaatgaaata agaataggac gaatcgttca
     2761 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
     2821 atctactata gtagctcaga agtcggtact taaacgtgct atatcaaaac cagtccttga
     2881 aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt taaaagttag
     2941 ttg
//
LOCUS       DBERAE010000084         2511 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.84, whole genome shotgun sequence.
ACCESSION   DBERAE010000084 DBERAE010000000
VERSION     DBERAE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.84"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            100..576
                     /locus_tag="ACL70N_002116"
     CDS             100..576
                     /locus_tag="ACL70N_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0590840.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            614..919
                     /locus_tag="ACL70N_002117"
     CDS             614..919
                     /locus_tag="ACL70N_002117"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0590841.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            967..2442
                     /locus_tag="ACL70N_002118"
     CDS             967..2442
                     /locus_tag="ACL70N_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGS0590842.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          759 a          482 c          496 g          774 t
ORIGIN      
        1 atataaaaaa agagacaaaa aagaacagaa agtaattgac aacggtttca tatagtgtta
       61 tacttatggc ataaagttaa tggaaagaag ggaaaactta tggtattaga ttatttcttt
      121 gacaaaaacc ttgtgttttg cttagaagcg gataatcaag aacaactctt tgatcaggtt
      181 gcaactttat tggaagaacg agaaattgtc actccaactt atcgtgaagc cttgatcacg
      241 cgtgaaaagt catttccaac tggtttagat atggaatttc taggaaagga cttgccaaat
      301 gtagcgattc ctcatacaga tattgttcat aatctagctg agaaagtggt ggttgttcga
      361 ttagaaaaac cagtaacttt tcacaatatg atagctcctg ataaggaagt agaagtatcc
      421 ttgctcttct ttatcatcaa taactcaagt tcaagtcaaa caaatattct ggctcagttg
      481 atggactttt tcacaggaaa tggacatctt gaagacctat caaaaatttc cgaaccagaa
      541 aaactttatg cttacattgc tgaaacaacc gcttaatctt gtctattaaa aaataaaatc
      601 ggaggaaatc taaatgatta aaattcttgc tgcctgcggt gcaggtgtta actcaagtca
      661 ccaaattaaa agtgctctag aagaagaact ttcaaaccgt ggttatgatg ttcactgtga
      721 tgcagtcatg gtgaaagatg taaacgaaga ccttatgaaa ggttacgata tctttacacc
      781 aatcgctgca acagaccttg gttttgaacc aggtatccca gttatcgaag ctggaccaat
      841 cttattccgt atcccagcaa tgagcgctcc agtatttgac aatattgaag cagctattaa
      901 agaacatgga ttaagctaat tctaatttgt taacattcat ataacataaa aaagggagga
      961 actgttatgg atgcaatctt tgacctaatc ggaaaggttt tcaatcccat cttagaaatg
     1021 ggtggacctg tcatcatgtt gatcattttg acagtattgg ctttactttt tggagtgaaa
     1081 ttctccaaag cgcttgaagg tggtatcaaa cttgccatcg ctcttacagg tatcggtgct
     1141 atcatcggta tgctaaatgg tgctttctca gcatcacttg caaaattcgt tgaaaacact
     1201 ggtatccaat tgagtattac agacgttggt tgggcaccac tcgcaacaat cacttggggt
     1261 tctgcttgga cactatactt cttgctcatc atgttgattg tcaacgtagt gatgcttgct
     1321 atgaagaaaa ccgatacact tgatgtcgat atctttgata tctggcactt gtctatcaca
     1381 ggtctcttga ttaaatggta tgctgataac aatggtgtga gtcaaggggt ttcactcttt
     1441 attgctacag cagctatcgt ccttgtcggt gtgttgaaaa ttatcaactc tgacttgatg
     1501 aaacctacat ttgatgacct tcttaacgcc ccaagttcat caccaatgac atcaactcac
     1561 atgaactaca tgatgaaccc agttatcatg gttttggata agatttttga aaaattcttc
     1621 ccaggccttg ataaatatga ctttgatgct gctaaattga acaagaaaat cggtttctgg
     1681 ggatctaaat tcttcatcgg tttcatcctt ggtatcgtta tcggtattat gggaactcca
     1741 catccaattg caggtgttgc agatgcagat aaatggcgtc ttgttatcaa aggatggttg
     1801 tctcttggtt tgactgccgg tgtatctttg gaactcttct cacttatcgg ttcatggttc
     1861 atcgcagccg tagaaccact atcacaaggt attacaaacg ttgctactaa acgtcttcaa
     1921 ggacgtaaat tcaatatcgg tcttgactgg ccattcatcg ctggtcgtgc tgaaatctgg
     1981 gcttgtgcca acgtacttgc accaatcatg ttgattgaag cagtgcttct ttcaaaagtt
     2041 ggaaatggta tcttgccact tgcaggtatc atcgctatgg gtgttactcc agctctcttg
     2101 gttgtaactc gtggtaaatt gctccgtatg attatcttcg gaacactctt gttgccactc
     2161 ttccttcttt caggtacact tattgcacca tttgcaacag aacttgctaa aggtgtaggt
     2221 gccttcccag aaggtgtgag ccaaactcaa ttgattactc actctactct tgaaggacca
     2281 atcgaaaaac ttcttggttg gacaattggt aacactacaa ctggtgatat caaagcaatc
     2341 cttggtgcag tagtcttcct tgtattctat atcggtatct ttgcttggta cagaaaacaa
     2401 atgatcaaac gtaacgaaga gtacgcagca aaagcaaaat aatgcgctcc tataaaatat
     2461 aaacttaatg aaaatcaaag agcaaactag gaagctagcc gcaggttgct c
//
LOCUS       DBERAE010000085         2188 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.85, whole genome shotgun sequence.
ACCESSION   DBERAE010000085 DBERAE010000000
VERSION     DBERAE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.85"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            15..1076
                     /gene="dinB"
                     /locus_tag="ACL70N_002119"
     CDS             15..1076
                     /gene="dinB"
                     /locus_tag="ACL70N_002119"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGS0590843.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILCAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(1223..2068)
                     /locus_tag="ACL70N_002120"
     CDS             complement(1223..2068)
                     /locus_tag="ACL70N_002120"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGS0590844.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT          727 a          446 c          440 g          575 t
ORIGIN      
        1 aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc
       61 atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag
      121 gaaaacctgt cattattgga agcgaccctc ggcaaacagg tggacgggga gtcgtttcta
      181 cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt
      241 atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg
      301 gactccagat tcgagctatt tttaagcgct atacagattt gattgaaccc atgagcattg
      361 acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg
      421 ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttct gccggtattt
      481 cctataacaa gttcttagct aaaatggcga gtgattatca aaaacctcat ggtttgacag
      541 tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg
      601 gagtaggaaa aaagacagta gaacgtcttc atcaaatggg cgtttttact ggtgctgatt
      661 tacttgaagt tcctgaggtg accctaatag accgttttgg tagactaggc tatgatctgt
      721 atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa
      781 tcggcaagga gaaaacctac gggaagattc tctgtgctga ggaagatatc aaaaaagagc
      841 tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa gctggaaaaa
      901 ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga aaaagtattg
      961 ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc tatgaagaat
     1021 taagtgagaa agaaagaggt gtccgcctat tggggattac catgactgga ttttaaagct
     1081 caatgaaaat caaagagcaa actaggaggc tagccgcagg ctgctcaaaa cactgttttg
     1141 aggttgcaga taaagctgac gcggtttgaa gagattttct aagagtataa aaccttgaag
     1201 agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa agtagcaaaa
     1261 cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc
     1321 tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc gcgaccaaga
     1381 gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg aaaatcttta
     1441 aggcactagc tccaaacata acaggaatcc caagatagaa ggtaaattct gtcacaactg
     1501 aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg ctagtccctg
     1561 gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa ggaagcttgt
     1621 ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc aaatagatga
     1681 aggcaacccc gtagataatc aacatgagag caactgaaac catgttatgg aagtgggtat
     1741 caaaccaatc atcaaattta aagacaccaa gtaaaggtaa agtagcaatc aagaccttca
     1801 accatagtct ccaagtctta cgaacttcct gtttgtcctt agtcggttta aaaggattga
     1861 gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc acgacattaa
     1921 acatggacat aaaggcttca ttttgatttt ggtattggat gaattcctct gctaaaatca
     1981 agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga
     2041 tagattttaa aatttcaata agatacatag attactccct atattataat tagcgcagtt
     2101 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc
     2161 ctccaatcgc ttgacgattt ccgaaagg
//
LOCUS       DBERAE010000086         2014 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.86, whole genome shotgun sequence.
ACCESSION   DBERAE010000086 DBERAE010000000
VERSION     DBERAE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.86"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            436..924
                     /locus_tag="ACL70N_002121"
                     /pseudo
     CDS             436..924
                     /locus_tag="ACL70N_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoD-type purine-nucleoside phosphorylase"
     gene            928..1155
                     /locus_tag="ACL70N_002122"
                     /pseudo
     CDS             928..1155
                     /locus_tag="ACL70N_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684207.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
     gene            complement(1178..1483)
                     /locus_tag="ACL70N_002123"
                     /pseudo
     CDS             complement(1178..1483)
                     /locus_tag="ACL70N_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
     gene            1531..>2014
                     /locus_tag="ACL70N_002124"
     CDS             1531..>2014
                     /locus_tag="ACL70N_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS0590845.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     F"
BASE COUNT          626 a          389 c          394 g          605 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttggtgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactagcgt tatcttaaat accgtggaaa agtcagagaa
      961 agtatggcgg cagattgccc tgaacgcttt gactgggagt ttatcagatg gattctttgg
     1021 gatggacgta gcaaaactca aaaagaaaat taccaaaaac tttgccaaga atattcacat
     1081 aaagtcacta ttcttcgaaa tcagagagag ctagatcaat ttctggataa gaaaaggaag
     1141 tcctacaatt cataaagggc ttcctttttg gctataatta ttctgcaatc aaggtttcca
     1201 aaccaacctt catcatatca gtgaaggtat tttgacgttc ttctgcagtt gtgtcttcgt
     1261 ctggattgac caagctatca gagatggtca tgatagctag cgcatcaaca tggtattggg
     1321 cagcaagata gtaaagagct gctgcttcca tttccacagc cttgactccc catttaccaa
     1381 gctcgatatt cttttcaaag taatttggct ctataatatt tgtagtgggt aaatccctta
     1441 tagatattat ggagcctatt tttgtgtaga aaaaaagtcc catatgacct ataatgaaaa
     1501 gcgacaaaac aactcattag aaagaatcat atggaacaat tacattttat cacaaaatta
     1561 ctagacatta aagaccctaa tatccagatt ttagacatca tcaataaaga tacacacaag
     1621 gaaatcatcg ccaaactgga ctacgacgcc ccatcttgcc ctgagtgcgg aagtcaaatg
     1681 aagaaatatg actttcaaaa accttctaaa attccttatc ttgaaacaac tggtatgcct
     1741 tctagaattc tccttagaaa acgccgtttc aagtgctatc actgttcaaa aatgatggtt
     1801 gctgagactc ccctggtaaa gaaaaatcac caaatccctc gtatcatcaa ccaaaaaatt
     1861 gctcaaaagt taattgaaaa aatttctatg actgatattg cccatcagct ggccatttca
     1921 acttcaactg tcattcgcaa gctcaatgac tttcactttg agcatgattt ttctcggctt
     1981 ccaaagatta tgtcttggga tgagtatgcc ttca
//
LOCUS       DBERAE010000087         1733 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.87, whole genome shotgun sequence.
ACCESSION   DBERAE010000087 DBERAE010000000
VERSION     DBERAE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.87"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            33..484
                     /locus_tag="ACL70N_002125"
                     /pseudo
     CDS             33..484
                     /locus_tag="ACL70N_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            649..948
                     /locus_tag="ACL70N_002126"
     CDS             649..948
                     /locus_tag="ACL70N_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGS0590846.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="ACL70N_002127"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="ACL70N_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0590847.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDDQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          578 a          335 c          308 g          512 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactctc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca aactgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcaac tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactaag cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaggt
     1201 attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtagcaaga
     1261 tagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
     1381 tttactggga tgatcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacacc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt
     1621 ttcattttac tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtcttt
     1681 aaaagtgttt tgatggtttg gatttcttct ttagttgatt tcatatcact att
//
LOCUS       DBERAE010000088         1722 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.88, whole genome shotgun sequence.
ACCESSION   DBERAE010000088 DBERAE010000000
VERSION     DBERAE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.88"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..821
                     /locus_tag="ACL70N_002128"
     CDS             <1..821
                     /locus_tag="ACL70N_002128"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0590848.1"
                     /translation="EKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPND
                     ESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRL
                     NDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRD
                     GDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPI
                     VQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            878..1675
                     /gene="psrA"
                     /locus_tag="ACL70N_002129"
     CDS             878..1675
                     /gene="psrA"
                     /locus_tag="ACL70N_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGS0590849.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          624 a          240 c          310 g          548 t
ORIGIN      
        1 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
       61 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
      121 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
      181 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
      241 gagatgataa ctcttattat gaggaagtac cttgtgaaat accagaaagt tgggagtggg
      301 tgaggttaaa cgatataacc tcctacattc aaagagggaa gtctccaaaa tattcaaata
      361 ttcctatata ccctgtgatt gctcagaaat gtaatcaatg gtctggcttt tctattgact
      421 tagcaagatt tattgatccc gaaacagttc atagttacca gaaagaaaga ttactaagag
      481 atggtgattt aatgtggaat tcaacaggtc taggtacgtt aggacgatta gctatttacc
      541 atgaaaataa aaatccttat ggctgggctg ttgcagatag ccatgttaca gttataagag
      601 tcttatcggg agttattaat tgccatttca tctataattt tctttcctct cctattgttc
      661 agtcagttat tgaagaaaaa gcgtcgggta gtacaaaaca aaaagaatta ttaacgaaaa
      721 ctataaaaga atatttaatc cccctcccac cccttcctga acaatccaga atcgttgata
      781 aaatcgaaca atttttcgcc catattgacg cactaattta gtataatagt tttacgtgcg
      841 gtggaatttc tatcaaacat aagataggag ttttacgttg aaagattttg aattacattt
      901 gaagaaagct ggtttagctg aaaatactgt gcgttcgtac ctttatggtg ttcgattttt
      961 cttggagaat tacgaactca aaatggaaga tttatttgaa tacaaaggat atttattaga
     1021 caattttaaa cctaaaactg tcaatttgcg actacaagga gtaaataaat atctggcttt
     1081 tattggtcat gatgatttga aattaaaatt tgtcaaagta cagcaaaaac cgtttttaga
     1141 agatgtcatt agccatgctg attacctttt tcttaaacgt agtttgaaaa aagatggtat
     1201 tttaaaatgg cattttgtcg tttggttttt aggtgcaact ggggctcgtg taagtgaact
     1261 tattaaacta aaagtagagc atgtagaaat cggttatttt gacatttact caaaaggtgg
     1321 taaaattcgt agactgtaca ttcctaaaaa attaagaaat agttgtctta gttggttaga
     1381 atcagaaaat cgccgaagtg gttatttatt tttgaataaa tttaacgaac caattacagc
     1441 aagaggagtt gctcaacagt taaaaaatta tgctgataaa tacaaaatga atcctaaagt
     1501 aatttaccct cattctttta gacatttatt tgctaagaat tttttagcga agtataatga
     1561 tattgccttg cttgcagatt tgatgggaca cgaaagtata gaaactactc gaatttatct
     1621 aaggaaaaca gctactgaac aacaaaatat tgtagataaa attgttaatt ggtaaaaaat
     1681 aacaggtggt caaactgact acctgctatt tttgtgatta tg
//
LOCUS       DBERAE010000089         1562 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.89, whole genome shotgun sequence.
ACCESSION   DBERAE010000089 DBERAE010000000
VERSION     DBERAE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.89"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>1562
                     /locus_tag="ACL70N_002130"
     CDS             <1..>1562
                     /locus_tag="ACL70N_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HGS0590850.1"
                     /translation="SSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQE
                     ILNATKDKASKSELTQTAEELSSKIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYTA
                     TIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYA
                     KANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQE
                     GTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSLEAGVNRLTEGLRTK
                     VDISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASK
                     SELTQTAEELASKIASVHLGRRNLLKGTKELARYKPVSEYNGFKVIRTVAGATRYQDS
                     YVERTVIPTAGTEYIAIFYARASENDYPVRCHFYNLNTVVSSENSSGYKSRSSDGLSI
                     IRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICAPAIFEGNLAGDW
                     SPAYEDQEDRVSA"
BASE COUNT          508 a          311 c          380 g          363 t
ORIGIN      
        1 agctcactca atgtgactgc tgaaaatatc cggcaatctg tgaagagtct tgagacagac
       61 acgcagaaca agctaaatca gaagttgagt caggctgaat ttgaggtgcg agctggctct
      121 atccgtcagg aaatcctgaa cgcaaccaag gataaagcca gcaagtcaga actcacgcag
      181 acagctgagg agctctctag taagatagcg agtgtgcagg catccggtcg aaatctattc
      241 ttgaactcac tattcaagca ggatattcca aaaacaggaa tttggacaac gagtacatat
      301 acggctacta tcgatagcga aagtaagtat cttggacata aggctcttaa aattataggt
      361 ctgaatccat ctggccgtga tggaggtaat cccaaggtta cttatccagc tctgggtcaa
      421 ttcgggaaag taattcccgg aagtacgact aatcaagatg taaccattag tttttatgct
      481 aaggcaaata aaaatggaat aatgctgaga tctcgattag ggaatatcgg atataaaact
      541 ggaaatgtga cattgtcgac agaaattaag cgatatgttg tccatattcc aaaaggttgg
      601 acaaacgaat ccaagcagac cacaaatgaa tggttgttca atttcaacca ggaaggaacc
      661 atttggattt ggatgccgaa gtttgaaata agcgatgtag atacttctta ttcagaagct
      721 cctgaagata tagaaggtca gatttcaaca gtagaatcga ccttcaaaca acgagccaac
      781 tcgctcgaag ctggtgtgaa tcgtctgact gaagggctta gaaccaaagt agatatcagc
      841 gcactcaatg tgactgctga aaatatccgg caatctgtga agagtcttga gacagacacg
      901 cagaacaaac taaatcagaa gttgagtcag gctgaatttg aggtgcgagc tggctctatc
      961 cgtcaggaaa tcctgaatgc aaccaaagat aaagccagca agtcagaact cacgcagaca
     1021 gctgaggagc tagctagtaa gatagcgagt gtgcacttag ggcgcagaaa tctgctgaaa
     1081 ggcacaaaag agcttgcgag atacaagccg gttagtgaat ataatggttt taaagttatc
     1141 agaacagtcg caggagcaac tagatatcag gatagctatg tggaaagaac cgttatacca
     1201 acggctggga cagagtatat agctatcttt tatgcacgag ccagtgaaaa tgactatcct
     1261 gtgcgctgtc atttttacaa tcttaatacg gttgtatcat cagaaaacag cagcggatat
     1321 aagtcaaggt cgtcagatgg cttgtctatt atccgtctct cgacagactg gcagttgtgc
     1381 tgggttaaat ggacccaaac cgcaacagat caagccaaga cggtcatcat tggccgccat
     1441 ggccctcaag taggcggtaa agagggggta tgggttgaaa tctgcgcccc tgccattttt
     1501 gagggaaatc ttgcaggtga ctggtcacca gcatacgaag accaagaaga ccgtgtctca
     1561 gc
//
LOCUS       DBERAE010000090         1063 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.90, whole genome shotgun sequence.
ACCESSION   DBERAE010000090 DBERAE010000000
VERSION     DBERAE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.90"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            333..584
                     /locus_tag="ACL70N_002131"
     CDS             333..584
                     /locus_tag="ACL70N_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGS0590851.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            572..862
                     /locus_tag="ACL70N_002132"
     CDS             572..862
                     /locus_tag="ACL70N_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0590852.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT          396 a          153 c          199 g          315 t
ORIGIN      
        1 gacttcgtca gttctatcca caacctcaaa acagtgtttt gagctgactt cgtcagtctt
       61 atctactacc tcaaaacagt gttttgagca acctgtggct agtttcctag tttgctcttt
      121 gattttcatt gagtacaaag agcttggcaa caggctcttt ttgtattgcg tttattaaga
      181 aaaacaaaaa acatcgatat acatttaact aaaaattatt gtatgttatc tcccttaatt
      241 aggaatgata agggaataac tagaaagatt tgtgaataca aactatttct gatatacaaa
      301 atatacagta ataatgaatg atgggagatg ggatgaaaga atttcaattt gagagaaagc
      361 agcgtttttc tttgaggcca tatgcaatag gagcttgttc ggtcttgcta ggaacgagtt
      421 tattttttgc tggtatgggt gctcagcctg tacaggatac agaaacgagt tcagcactaa
      481 tttcaagtca ttatttggat gagcaggatt tatctgaaaa gctgaaatct gagttgcaat
      541 ggtttgaatt agaaaacaag cttttgaact tatgggagca ttaggttact atgaaggatt
      601 tgttccttat gtttcaaatc aatacaaaaa ccaagctgaa gaagaaggca aaccgctatc
      661 tgataaatat attttcgaaa aaatcttagg aaaaacatat gcagccttca aaaaagatca
      721 aattaatgag cgtgtcgaga aattaggtaa gttaaaacct attacaataa attacaacgg
      781 aaaatcagaa gtaattgata gtaaagaaaa attacaagag cttatgaata aagccgttaa
      841 agacgaagtg gctcaaatat agtaaaatga aataagaaca ggataaatcg atcaggacag
      901 tcaaatcgat ttctaaaaat gttttagaag tagaggtgta ctattctagt ttcaatatac
      961 tataaaatca ggcaatacca cggctaaaaa gtttgagttt atcgaaacac cagtgcaaaa
     1021 actgaaaaaa gcgatttata aagctcatct caaagattca gat
//
LOCUS       DBERAE010000091         1044 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.91, whole genome shotgun sequence.
ACCESSION   DBERAE010000091 DBERAE010000000
VERSION     DBERAE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.91"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..550
                     /locus_tag="ACL70N_002133"
     CDS             <1..550
                     /locus_tag="ACL70N_002133"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0590853.1"
                     /translation="ETTSYPIYEIPKAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(498..>1044)
                     /locus_tag="ACL70N_002134"
     CDS             complement(498..>1044)
                     /locus_tag="ACL70N_002134"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0590854.1"
                     /translation="PMNWVVIKIKDIFSINTGLSYKKGDLSINKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          373 a          167 c          152 g          352 t
ORIGIN      
        1 cgaaacaacc tcttatccta tatatgaaat cccaaaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccctgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgcttagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgctc agaggagatg aattgtgtgt caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 atgcttaaat cgcccttctt gtaagaaaga cctgtattta ttgaaaaaat atcttttatt
     1021 tttataacaa cccaattcat aggt
//
LOCUS       DBERAE010000092          990 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.92, whole genome shotgun sequence.
ACCESSION   DBERAE010000092 DBERAE010000000
VERSION     DBERAE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.92"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            146..310
                     /locus_tag="ACL70N_002135"
     CDS             146..310
                     /locus_tag="ACL70N_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0590855.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            307..711
                     /locus_tag="ACL70N_002136"
     CDS             307..711
                     /locus_tag="ACL70N_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS0590856.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          294 a          153 c          176 g          367 t
ORIGIN      
        1 atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta tgatttgagt
       61 gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc aactaagata
      121 aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt tcgttctgta
      181 tctaatcatg tccatctttc tatatccgct tagggagagt gcttggtatc agctatttta
      241 taccatagcc tatgtgattg cagttatgat ctattttgct atcaataaaa agaaaggaga
      301 aaagaaatga aaacttttct tgctaaaaaa cggaacatct tccttgcgag attgttctta
      361 ggtcagttgc ccttgcttgt ttctacttat ctatttctat ctcgtcagtt tttaaatttt
      421 tccgtagttt tccaatttct tttagtagtt attaacttgg cttctatttt ggttactgtt
      481 tatctcacta gggaaatgag gataagagag tttgaagatg atgatttggt tagtcctaga
      541 accaatcaac ttatgttcat cggcttgaca ggttttatgt ctattatttg tttgtataga
      601 ggtatcacag caggagaatc ctaccaacaa ataatcgctt atattggcgc tgttctctgc
      661 ttaatcatca tgcttctgct catgtggggc ttgaagtatt ataaaaagta gagcttaatg
      721 aagtataaaa gaaaagggta agtgtttttg caatacttac ccttttataa tagattccct
      781 gcgaaacaaa atatggtata gtatagtaga ttgaaactag aatagtacgc ctctatttct
      841 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tatcctgttc ttatttcatt
      901 ttactatagt tctatgaatt atgaagcaag taaacaacta accgatgcac gatttaagcg
      961 tcttgttggt gttcagcgta ccacttttga
//
LOCUS       DBERAE010000093          662 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.93, whole genome shotgun sequence.
ACCESSION   DBERAE010000093 DBERAE010000000
VERSION     DBERAE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.93"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            77..439
                     /locus_tag="ACL70N_002137"
     CDS             77..439
                     /locus_tag="ACL70N_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGS0590857.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          220 a           81 c          121 g          240 t
ORIGIN      
        1 aacttcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt
       61 cattgagtat aacagattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt
      121 taccttcgat atattatatc ccatagttaa ggttggtcat acagatgatt atagtcatgg
      181 agccgtaaaa cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac
      241 tgtaatagga tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa
      301 tggtactgct attctttatc attatttacg ttctattgtt tcaatagttt cggcaattga
      361 tagcagtgaa gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca
      421 accttttgaa gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaatc
      481 agtaagaaaa atgtcttgca ttatacagca accttttggg aatgagtaga tggattgaat
      541 aaaattttat taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa
      601 gtagtctaag aattaggtta taatcagtag aatccttgct aataatgagg aggttagttt
      661 at
//
LOCUS       DBERAE010000094          528 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.94, whole genome shotgun sequence.
ACCESSION   DBERAE010000094 DBERAE010000000
VERSION     DBERAE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.94"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>528)
                     /locus_tag="ACL70N_002138"
     CDS             complement(<1..>528)
                     /locus_tag="ACL70N_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGS0590858.1"
                     /translation="FDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPY
                     YDLAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQ
                     DSRKLSDKRFYRPTFRIHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFF
                     GLIEDNLKQVHPIFQT"
BASE COUNT          170 a           83 c          112 g          163 t
ORIGIN      
        1 agtctgaaaa ataggatgaa cctgcttcag attgtcctca atgagtccga aaaatttctc
       61 agggtctttg ttctgaaagt gaaaaagtaa gagttgatag atctgatagt ggtgtttcaa
      121 gtcttctgaa tagcttaaaa tcttgtcaag aatttcttta tttgttaagt gtatgcgaaa
      181 agtagggcga taaaaacgtt tatcgctgag tttacgacta tcctgttgga tgagtttcca
      241 gtaacgcttg atagccttgt attcatgaga ttttcgttca aactgattca taatttgaac
      301 acgaaaacga ctcatggcac ggctgagatg ttggataata tggaaacgat ctagaacgat
      361 tttagcacac ggaaaaagct gtttagccaa gtcatagtaa ggactaaaca tatccatcgt
      421 aatgattttc acttgacaac gaacggctct atcgtagcga agaaagtgat ttcggatgac
      481 agcttgtgtt ctgccttcaa gaacagtgat aatattaaga ttatcaaa
//
LOCUS       DBERAE010000095          504 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.95, whole genome shotgun sequence.
ACCESSION   DBERAE010000095 DBERAE010000000
VERSION     DBERAE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.95"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>504
                     /locus_tag="ACL70N_002139"
     CDS             <1..>504
                     /locus_tag="ACL70N_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0590859.1"
                     /translation="TQEIDVPYDIPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDG
                     INWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGA
                     IHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLP
                     PLSEQQRI"
BASE COUNT          173 a           72 c           89 g          170 t
ORIGIN      
        1 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggttttct
       61 acattggttg aaattgtcag aggtggctct ccacgaccaa tcaaagatta tcttacttct
      121 gaagtagatg gaataaattg gataaaaata ggtgatactg aaaagggtga aaagtatata
      181 aataatgtta aagaaaaaat caaaaaatca gggcttaaca aaactagatt tgtaaaaaaa
      241 ggtacatttt tgttaactaa ttctatgagt tttggtagac cttatatttt gaatgttgat
      301 ggtgcaatac acgatggatg gttggctatt tcgaactatg aaaactcatt aaataaagat
      361 tatctattct atattctttc atcaaatgta gtttattctc aatttctatc tctaattagt
      421 ggagctgttg tgaaaaactt gaatagtgat aaagttgctt ctattcttat ccctctcccc
      481 ccactatccg aacaacaacg cata
//
LOCUS       DBERAE010000096          499 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.96, whole genome shotgun sequence.
ACCESSION   DBERAE010000096 DBERAE010000000
VERSION     DBERAE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.96"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>499
                     /locus_tag="ACL70N_002140"
     CDS             <1..>499
                     /locus_tag="ACL70N_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS0590860.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMP
                     YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPN
                     ERPHS"
BASE COUNT          161 a          104 c          113 g          121 t
ORIGIN      
        1 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
       61 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      121 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      181 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      241 caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg ccacttgatc
      301 gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta atcatacctc
      361 attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt tatgaggcac
      421 ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc gaacatccaa
      481 acgaacgtcc gcattcaga
//
LOCUS       DBERAE010000097          486 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 466184
            SAMN38107327-rid24764943.denovo.97, whole genome shotgun sequence.
ACCESSION   DBERAE010000097 DBERAE010000000
VERSION     DBERAE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107327
            Sequence Read Archive: SRR26673679
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570899.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570899.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:19:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,095
            Genes (coding)                    :: 1,957
            CDSs (with protein)               :: 1,957
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 68 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 43 of 138
            Pseudo Genes (multiple problems)  :: 36 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107327-rid24764943.denovo.97"
                     /strain="GPSC19"
                     /isolate="466184"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>486
                     /locus_tag="ACL70N_002141"
     CDS             <1..>486
                     /locus_tag="ACL70N_002141"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0590861.1"
                     /translation="TQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTSSID
                     RKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIAST
                     AFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQ
                     RI"
BASE COUNT          177 a           75 c           71 g          163 t
ORIGIN      
        1 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggataaaa
       61 tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta tatagatacg
      121 tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata tctttcacct
      181 gaacaagcgc cttcccgtgc tagaaaatta gtttcgcaga atagtgtctt attttcaaca
      241 gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta tttgatagct
      301 agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa atattattta
      361 ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag ttatcctgca
      421 atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc cgaacaacaa
      481 cgaata
//
